Funded by the National Institute on Drug Abuse Third National Conference Stress and Addiction: From Molecule to Neighborhood Wyndham Miami Beach Resort 4833 Collins Avenue Miami Beach, FL 33140 October 2-4, 2003 Funded by the National Institute on Drug Abuse Third National Conference Stress and Addiction: From Molecule to Neighborhood Wyndham Miami Beach Resort 4833 Collins Avenue Miami Beach, FL 33140 October 2-4, 2003 National Hispanic Science Network on Drug Abuse Mission Statement he National Hispanic Science Network on TDrug Abuse is dedicated to improving the health of Hispanics by: 1) Increasing the amount and quality of interdisciplinary translational research on drug abuse; and, 2) Fostering the development of Hispanic scientists in drug abuse research. 2 National Steering Committee José Szapocznik, Ph.D. Patricia Molina, M.D., Ph.D. Chair, NHSN Associate Professor Professor & Director Department of Psychology Center for Family Studies Louisiana State University Department of Psychiatry & Behavioral Sciences University of Miami School of Medicine J. Bryan Page, Ph.D. Professor and Chair Hortensia Amaro, Ph.D. Department of Anthropology Distinguished Professor & Director University of Miami Institute on Urban Health Research Bouvé College of Health Sciences Northeastern University Rafaela R. Robles, Ed.D. Professor Department of Community Health Ana Mari Cauce, Ph.D. Universidad Central del Caribe Professor and Chair Department of Psychology University of Washington Daniel Santisteban, Ph.D. Associate Professor Department of Psychiatry & Behavioral Sciences Alexander Kopelowicz, M.D. University of Miami School of Medicine Associate Professor Department of Psychiatry University of California at Los Angeles Avelardo Valdéz, Ph.D. Professor Graduate School of Social Work Joe L. Martínez, Ph.D. University of Houston Ewing Halsell Professor of Neuroscience Department of Biology University of Texas at San Antonio William A. Vega, Ph.D. Professor Department of Psychiatry UMDNJ/ Robert Wood Johnson Medical School 3 Thursday, October 2, 2003 Scientific Program 8:00 a.m. - 5:30 p.m. Registration Grand Promenade Foyer, Lobby Level 12:00 p.m. - 1:30 p.m. Opening Luncheon Grand Promenade Room, Lobby Level Welcoming José Szapocznik, Ph.D. Remarks: Chair, NHSN University of Miami School of Medicine Ana Anders, L.I.C.S.W. Senior Advisor, Special Populations Office National Institute on Drug Abuse Conference William A. Vega, Ph.D. Overview: Chair, NHSN 2003 Conference Planning Subcommittee UMDNJ/ Robert Wood Johnson Medical School Featured Andrea Barthwell, M.D., F.A.S.A.M. Speaker: Deputy Director for Demand Reduction White House Office of National Drug Control Policy 1:30 p.m. - 1:45 p.m. BREAK *** All presentations in Regency Ballroom, Lobby Level*** 1:45 p.m. - 3:30 p.m. Putative Social and Biologic Mechanisms Affecting the Stress Relationship to Drug Abuse Chair & Joe L. Martínez, Ph.D. Discussant: University of Texas at San Antonio Presenters: Patricia Molina, M.D., Ph.D. Louisiana State University “Neurobiology of the Stress Response” William A. Vega, Ph.D. UMDNJ/ Robert Wood Johnson Medical School “Stress and Cultural Adaptation: Why are Latino Drug Use Rates Higher in the U.S. than in Nations of Origin?” Avelardo Valdéz, Ph.D. University of Houston “Social Capital, Substance Use and Stress” 4 Thursday, October 2, 2003 Scientific Program 3:30 p.m. - 3:45 p.m. BREAK 3:45 p.m. - 5:30 p.m. Predisposing Factors and Neurobiologic Substrates Chair & George A. Ricaurte, M.D., Ph.D. Discussant: Johns Hopkins University Presenters: Jon Kar Zubieta, Ph.D. University of Michigan “Brain Circuits in Addiction“ Kathleen Ries Merikangas, Ph.D. National Institute of Mental Health ”Migrant Study of Substance Use Disorders in Puerto Rican Families“ María Elena Medina-Mora, Ph.D. National Institute of Psychiatry of Mexico “Differences in U.S.-Mexico Drug Use Patterns Based on the Results of the National Household Surveys on Addictions and Other Studies” 5:30 p.m. Adjourn Scientific Program 5:30 p.m. - 6:00 p.m. NHSN Membership Photo Session Grand Promenade Room, Lobby Level All NHSN Scientist and Student Members, please proceed to the Grand Promenade Room where group photographs will be taken. 6:00 p.m. - 7:00 p.m. BREAK 7:00 p.m. - 9:00 p.m. Dinner and Awards Ceremony Starlight Ballroom, 18th Floor Hortensia Amaro, Ph.D. Northeastern University William A. Vega, Ph.D. UMDNJ/ Robert Wood Johnson Medical School 9:00 p.m. - 11:00 p.m. Social Event Starlight Ballroom, 18th Floor 5 Friday, October 3, 2003 Scientific Program 8:00 a.m. - 9:00 a.m. Breakfast Grand Promenade Room, Lobby Level 8:00 a.m. - 5:30 p.m. Registration Grand Promenade Foyer, Lobby Level 8:00 a.m. - 5:30 p.m. Poster Session Mediterranean Room Center, Lobby Level Posters available for viewing all day. See pages 12 & 13 for Poster titles and authors. *** All presentations in Regency Ballroom, Lobby Level*** 9:00 a.m. - 10:00 a.m. Keynote Address Nora Volkow, M.D. Director, National Institute on Drug Abuse 10:00 a.m. - 10:15 a.m. BREAK 10:15 a.m. - 12:15 p.m. Prevention Science: Cultural Relevance from Molecular Mechanisms to Community Interventions Chair & Felipe González-Castro, Ph.D. Discussant: Arizona State University Presenters: William A. Carlezon, Ph.D. Harvard University “Biological Mechanisms of Aversive States in Drug Addiction” Hilda Pantín, Ph.D. University of Miami School of Medicine “Familias Unidas: A Preventive Intervention for Latino Adolescents and Families in Urban Environments” Charles Martínez, Ph.D. Oregon Social Learning Center “Adapting Preventive Intervention Models for Communities Undergoing Rapid Sociodemographic Shifts” 12:15 p.m. - 1:45 p.m. Mentoring Luncheon Grand Promenade Room, Lobby Level Seating for the Mentoring Luncheon has been pre-arranged based on information provided by the conference participants. Please refer to the seating chart in your registration packet for your assigned table. 6 Friday, October 3, 2003 Scientific Program 1:45 p.m. - 2:00 p.m. BREAK 2:00 p.m. - 4:00 p.m. Multiple Levels of Intervention Targets in Addiction Treatment and Relapse Prevention Chair & Daniel Santisteban, Ph.D. Discussant: University of Miami School of Medicine Presenters: Diana Martínez, M.D. Columbia University “Imaging the Neurobiology of Addiction” Hortensia Amaro, Ph.D. Northeastern University “Treatment Retention Among Hispanic Women: Findings and Questions for Future Research” Rafaela R. Robles, Ed.D. Universidad Central del Caribe “Effects of a Two-Facet Intervention to Reduce HIV Risk Behaviors Among Hispanic Drug Injectors in Puerto Rico: A Randomized Controlled Study” 4:00 p.m. Adjourn Scientific Program 4:00 p.m. - 5:30 p.m. Poster Session and Reception Mediterranean Room Center, Lobby Level Chair: Charles Martínez, Ph.D. Oregon Social Learning Center Co-Chair: Steve R. López, Ph.D. University of California at Los Angeles See pages 12 & 13 for Poster titles and authors. 7 Saturday, October 4, 2003 8:00 a.m. - 9:00 a.m. Breakfast Grand Promenade Room, Lobby Level 9:00 a.m. - 10:30 a.m. National Network Meeting: National Strategic Plan on Hispanic Drug Abuse Research Chair: Hortensia Amaro, Ph.D. Northeastern University 10:30 a.m. - 10:45 a.m. BREAK 10:45 a.m. - 12:00 p.m National Network Meeting: National Strategic Plan (Continued) 12:00 p.m - 12:45 p.m. Working Lunch - National Network Meeting: National Strategic Plan 12:45 p.m. Adjourn National Network Meeting 12:45 p.m. - 1:00 p.m. BREAK 1:00 p.m. - 3:00 p.m. Research Funding and Career Development Workshop Co-Chair: Angela Pattatucci-Aragón, Ph.D. University of Puerto Rico Co-Chair: Iván Montoya, M.D., M.P.H. National Institute on Drug Abuse New Funding Priorities and Initiatives Chair: Iván Montoya, M.D., M.P.H. National Institute on Drug Abuse Panelists: Jerry Flanzer, D.S.W. National Institute on Drug Abuse Eleanor McLellan-Lemal, M.A. Centers for Disease Control and Prevention Susan F. Newcomer, Ph.D. National Institute of Child Health & Human Development Tracy Enright Patterson, M.A. Wake Forest University School of Medicine Robert Wood Johnson Foundation Mónica S. Ruiz, Ph.D., M.P.H. National Institute of Allergy and Infectious Diseases 8 Saturday, October 4, 2003 3:00 p.m. - 3:15 p.m. BREAK 3:15 p.m. - 5:00 p.m. Research Funding and Career Development Workshop (Continued) Grant Review and Grant Post-Submission Issues Panel Chair: Eduardo Montalvo, Ph.D. Center for Scientific Review National Institutes of Health Panelists: Alexander N. Ortega, Ph.D., M.P.H. Ohio State University Jesús Ramírez Vallez, Ph.D. University of Illinois Mildred Vera, Ph.D. University of Puerto Rico María Cecilia Zea, Ph.D. George Washington University 5:00 p.m. Adjourn Research Funding and Career Development Workshop 9 ABSTRACTS Putative Social and Biologic Mechanisms Affecting the Stress Relationship to Drug Abuse Chair & Discussant: Joe L. Martínez, Jr., Ph.D. University of Texas at San Antonio Stress contributes to drug abuse in at least two ways: by influencing brain function directly, and through psychological mediation. Patricia E. Molina, M.D., Ph.D., will review evidence indicating that physical and psychological stress is associated with a higher incidence of drug abuse. In particular, the hippocampus is a sensitive target for the damage produced by the stress response. The challenge remains to understand how this structure may contribute to drug abuse in vulnerable individuals. Avelardo Valdéz, Ph.D., will illustrate how a measure of social capital may mediate the relationship of stress as an antecedent to substance use and other risk behaviors. William Vega, Ph.D., will review evidence for a "Hispanic paradox" in drug abuse, including epidemiologic findings that support a social stress and social assimilation explanation. Risk factors for immigrants and U.S.-born Latinos will be examined.