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(DMT), Harmine, Harmaline and Tetrahydroharmine: Clinical and Forensic Impact
pharmaceuticals Review Toxicokinetics and Toxicodynamics of Ayahuasca Alkaloids N,N-Dimethyltryptamine (DMT), Harmine, Harmaline and Tetrahydroharmine: Clinical and Forensic Impact Andreia Machado Brito-da-Costa 1 , Diana Dias-da-Silva 1,2,* , Nelson G. M. Gomes 1,3 , Ricardo Jorge Dinis-Oliveira 1,2,4,* and Áurea Madureira-Carvalho 1,3 1 Department of Sciences, IINFACTS-Institute of Research and Advanced Training in Health Sciences and Technologies, University Institute of Health Sciences (IUCS), CESPU, CRL, 4585-116 Gandra, Portugal; [email protected] (A.M.B.-d.-C.); ngomes@ff.up.pt (N.G.M.G.); [email protected] (Á.M.-C.) 2 UCIBIO-REQUIMTE, Laboratory of Toxicology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal 3 LAQV-REQUIMTE, Laboratory of Pharmacognosy, Department of Chemistry, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal 4 Department of Public Health and Forensic Sciences, and Medical Education, Faculty of Medicine, University of Porto, 4200-319 Porto, Portugal * Correspondence: [email protected] (D.D.-d.-S.); [email protected] (R.J.D.-O.); Tel.: +351-224-157-216 (R.J.D.-O.) Received: 21 September 2020; Accepted: 20 October 2020; Published: 23 October 2020 Abstract: Ayahuasca is a hallucinogenic botanical beverage originally used by indigenous Amazonian tribes in religious ceremonies and therapeutic practices. While ethnobotanical surveys still indicate its spiritual and medicinal uses, consumption of ayahuasca has been progressively related with a recreational purpose, particularly in Western societies. The ayahuasca aqueous concoction is typically prepared from the leaves of the N,N-dimethyltryptamine (DMT)-containing Psychotria viridis, and the stem and bark of Banisteriopsis caapi, the plant source of harmala alkaloids. -
The Science of Mediumship and the Evidence of Survival
Rollins College Rollins Scholarship Online Master of Liberal Studies Theses 2009 The cS ience of Mediumship and the Evidence of Survival Benjamin R. Cox III [email protected] Follow this and additional works at: http://scholarship.rollins.edu/mls Recommended Citation Cox, Benjamin R. III, "The cS ience of Mediumship and the Evidence of Survival" (2009). Master of Liberal Studies Theses. 31. http://scholarship.rollins.edu/mls/31 This Open Access is brought to you for free and open access by Rollins Scholarship Online. It has been accepted for inclusion in Master of Liberal Studies Theses by an authorized administrator of Rollins Scholarship Online. For more information, please contact [email protected]. The Science of Mediumship and the Evidence of Survival A Thesis Submitted in Partial Fulfillment of the Requirements for the Degree of Master of Liberal Studies by Benjamin R. Cox, III April, 2009 Mentor: Dr. J. Thomas Cook Rollins College Hamilton Holt School Master of Liberal Studies Winter Park, Florida This project is dedicated to Nathan Jablonski and Richard S. Smith Table of Contents Introduction ............................................................................................... 1 The Science of Mediumship.................................................................... 11 The Case of Leonora E. Piper ................................................................ 33 The Case of Eusapia Palladino............................................................... 45 My Personal Experience as a Seance Medium Specializing -
Historical Perspective
Journal of Scientific Exploration, Vol. 34, No. 4, pp. 717–754, 2020 0892-3310/20 HISTORICAL PERSPECTIVE Early Psychical Research Reference Works: Remarks on Nandor Fodor’s Encyclopaedia of Psychic Science Carlos S. Alvarado [email protected] Submitted March 11, 2020; Accepted July 5, 2020; Published December 15, 2020 DOI: 10.31275/20201785 Creative Commons License CC-BY-NC Abstract—Some early reference works about psychic phenomena have included bibliographies, dictionaries, encyclopedias, and general over- view books. A particularly useful one, and the focus of the present article, is Nandor Fodor’s Encyclopaedia of Psychic Science (Fodor, n.d., circa 1933 or 1934). The encyclopedia has more than 900 alphabetically arranged entries. These cover such phenomena as apparitions, auras, automatic writing, clairvoyance, hauntings, materialization, poltergeists, premoni- tions, psychometry, and telepathy, but also mediums and psychics, re- searchers and writers, magazines and journals, organizations, theoretical ideas, and other topics. In addition to the content of this work, and some information about its author, it is argued that the Encyclopaedia is a good reference work for the study of developments from before 1933, even though it has some omissions and bibliographical problems. Keywords: Encyclopaedia of Psychic Science; Nandor Fodor; psychical re- search reference works; history of psychical research INTRODUCTION The work discussed in this article, Nandor Fodor’s Encyclopaedia of Psychic Science (Fodor, n.d., circa 1933 or 1934), is a unique compilation of information about psychical research and related topics up to around 1933. Widely used by writers interested in overviews of the literature, Fodor’s work is part of a reference literature developed over the years to facilitate the acquisition of knowledge about the early publications of the field by students of psychic phenomena. -
Effects of Ayahuasca on Psychometric Measures of Anxiety, Panic-Like and Hopelessness in Santo Daime Members R.G
Journal of Ethnopharmacology 112 (2007) 507–513 Effects of ayahuasca on psychometric measures of anxiety, panic-like and hopelessness in Santo Daime members R.G. Santos a,∗, J. Landeira-Fernandez b, R.J. Strassman c, V. Motta a, A.P.M. Cruz a a Departamento de Processos Psicol´ogicos B´asicos, Instituto de Psicologia, Universidade de Bras´ılia, Asa Norte, Bras´ılia-DF 70910-900, Brazil b Department of Psychiatry, University of New Mexico School of Medicine, Albuquerque, NM 87131, USA c Departamento de Psicologia, Pontif´ıcia Universidade Cat´olica do Rio de Janeiro, PUC-RJ, Brazil Received 21 December 2006; received in revised form 16 April 2007; accepted 18 April 2007 Available online 25 April 2007 Abstract The use of the hallucinogenic brew ayahuasca, obtained from infusing the shredded stalk of the malpighiaceous plant Banisteriopsis caapi with the leaves of other plants such as Psychotria viridis, is growing in urban centers of Europe, South and North America in the last several decades. Despite this diffusion, little is known about its effects on emotional states. The present study investigated the effects of ayahuasca on psychometric measures of anxiety, panic-like and hopelessness in members of the Santo Daime, an ayahuasca-using religion. Standard questionnaires were used to evaluate state-anxiety (STAI-state), trait-anxiety (STAI-trait), panic-like (ASI-R) and hopelessness (BHS) in participants that ingested ayahuasca for at least 10 consecutive years. The study was done in the Santo Daime church, where the questionnaires were administered 1 h after the ingestion of the brew, in a double-blind, placebo-controlled procedure. -
Dissociation and the Unconscious Mind: Nineteenth-Century Perspectives on Mediumship
Journal of Scientifi c Exploration, Vol. 34, No. 3, pp. 537–596, 2020 0892-3310/20 HISTORICAL PERSPECTIVE Dissociation and the Unconscious Mind: Nineteenth-Century Perspectives on Mediumship C!"#$% S. A#&!"!'$ Parapsychology Foundation [email protected] Submitted December 18, 2019; Accepted March 21, 2020; Published September 15, 2020 https://doi.org/10.31275/20201735 Creative Commons License CC-BY-NC Abstract—There is a long history of discussions of mediumship as related to dissociation and the unconscious mind during the nineteenth century. A! er an overview of relevant ideas and observations from the mesmeric, hypnosis, and spiritualistic literatures, I focus on the writings of Jules Baillarger, Alfred Binet, Paul Blocq, Théodore Flournoy, Jules Héricourt, William James, Pierre Janet, Ambroise August Liébeault, Frederic W. H. Myers, Julian Ochorowicz, Charles Richet, Hippolyte Taine, Paul Tascher, and Edouard von Hartmann. While some of their ideas reduced mediumship solely to intra-psychic processes, others considered as well veridical phenomena. The speculations of these individuals, involving personation, and di" erent memory states, were part of a general interest in the unconscious mind, and in automatisms, hysteria, and hypnosis during the period in question. Similar ideas continued into the twentieth century. Keywords: mediumship; dissociation; secondary personalities; Frederic W. H. Myers; Théodore Flournoy; Pierre Janet INTRODUCTION Dissociation, a process involving the disconnection of a sense of identity, physical sensations, and memory from conscious experience, has been related to mediumship due to the latter’s sensory and motor automatism and changes of identity. In recent years there have been some conceptual discussions of dissociation and mediumship (e.g., Maraldi et al., 2019) as well as empirical studies exploring their 538 Carlos S. -
In the Supreme Court of the United States
No. 04-1084 In the Supreme Court of the United States ALBERTO R. GONZALES, ATTORNEY GENERAL, ET AL., PETITIONERS v. O CENTRO ESPIRITA BENEFICIENTE UNIAO DO VEGETAL, ET AL. ON WRIT OF CERTIORARI TO THE UNITED STATES COURT OF APPEALS FOR THE TENTH CIRCUIT JOINT APPENDIX (VOLUME 1) PAUL D. CLEMENT NANCY HOLLANDER Solicitor General Freedman Boyd Daniels Department of Justice Hollander & Goldberg P.A. Washington, D.C. 20530-0001 20 First Plaza, Suite 700 (202) 514-2217 Albuquerque, NM 87102 (505) 842-9960 Counsel of Record Counsel of Record for Petitioners for Respondents PETITION FOR A WRIT OF CERTIORARI FILED: FEB. 10, 2005 CERTIORARI GRANTED: APR. 18, 2005 TABLE OF CONTENTS Page Court of appeals docket entries ........................................ 1 District court docket entries ............................................. 10 Plaintiffs’ original complaint (Nov. 21, 2000) .................. 17 Answer to plaintiffs’ original complaint (Feb. 1, 2001) ............................................................................... 37 Declaration of Jeffrey Bronfman (Nov. 17, 2000) (Plaintiffs’ Exh. A) ....................................................... 49 Human Psychopharmacology of Hoasca, etc. (Vol. 184, No. 3, 1996) (Plaintiffs’ Exh. G) ............... 75 District court order (May 31, 2001) .................................. 102 Index and mailing list of churches (Defendants’ Exh. D) ........................................................................... 105 Expert Report of Dr. Sander G. Genser (undated) (Defendants’ Exh. ZZ) -
Ii an INVESTIGATION of PERSONAL TRANSFORMATIONS AND
AN INVESTIGATION OF PERSONAL TRANSFORMATIONS AND PSYCHOACTIVE PLANT USE IN SYNCRETIC RITUAL CEREMONIES IN A BRAZILIAN CHURCH by Michael Cougar Copyright © Michael Cougar 2005 All Rights Reserved ii Abstract An Investigation of Personal Transformations and Psychoactive Plant Use in Syncretic Ritual Ceremonies in a Brazilian Church by Michael Cougar Fifty-two North American and European participants in syncretic Brazilian church religious ceremonies were assessed for indications of personality and clinical disorders, and tendencies towards chemical dependency and addiction. Research participants attended at least 6 syncretic ceremonies and consumed a psychoactive tea, Daime, which is made from 2 Amazon Basin rainforest plants, the rainha and jagube. The research sample completed the Clinical Analysis Questionnaire (CAQ), a standardized assessment designed to reveal tendencies toward clinical and personality disorders and chemical dependence. Subgroups of the research sample (based upon age, gender, length of time associated with the Santo Daime Church, number of Festivals attended, average number of ceremonies per Festival, and preexisting diagnoses for clinical disorders) also were assessed. The norm population scores initially were compared to the research sample scores, and then compared to sample subgroup scores for each subgroup. Statistical analyses of the assessment scales scores were performed using t tests and ANOVA. Statistical analyses generally revealed no tendencies toward psychopathology or chemical dependence within the research sample. This study reveals the benefits of ethological analyses of psychoactive substance use. iii Dedication This project is dedicated to the past and present indigenous peoples of the world whose intuitive knowledge made exploration of the benefits of plant medicines possible. iv Preface While on an extended vacation several years ago, traveling on a tributary of Brazil’s Purus River, the motorized canoe in which I was riding was hit by a speed boat. -
Road to Spiritism
THE ROAD TO SPIRITISM By MARIA ENEDINA LIMA BEZERRA A DISSERTATION PRESENTED TO THE GRADUATE SCHOOL OF THE UNIVERSITY OF FLORIDA IN PARTIAL FULFILLMENT OF THE REQUIREMENTS FOR THE DEGREE OF DOCTOR OF PHILOSOPHY UNIVERSITY OF FLORIDA 2002 Copyright 2002 By Maria Enedina Lima Bezerra To my beloved parents, Abelardo and Edinir Bezerra, for all the emotional and spiritual support that they gave me throughout this journey; and to the memory of my most adored grandmother, Maria do Carmo Lima, who helped me sow the seeds of the dream that brought me here. ACKNOWLEDGMENTS My first expressions of gratitude go to my parents for always having believed in me and supported my endeavors and for having instilled in me their heart-felt love for learning and for peoples and lands beyond our own. Without them, I would not have grown to be such a curious individual, always interested in leaving my familiar surroundings and learning about other cultures. My deepest gratitude goes to the Spiritists who so warmly and openly welcomed me in their centers and so generously dedicated their time so that 1 could conduct my research. With them I learned about Spiritism and also learned to accept and respect a faith different from my own. It would be impossible for me to list here the names of all the Spiritists I interviewed and interacted with. In particular, I would like to thank the people of Grupo Espirita Paulo e Estevao, Centra Espirita Pedro, o Apostolo de Jesus, and Centro Espirita Grao de Mostarda. Without them, this study would not have been possible. -
2. the Notion of Cure in the Brazilian Ayahuasca Religions
T Transworld Research Network 37/661 (2), Fort P.O. Trivandrum-695 023 Kerala, India The Ethnopharmacology of Ayahuasca, 2011: 23-53 ISBN: 978-81-7895-526-1 Editor: Rafael Guimarães dos Santos 2. The notion of cure in the Brazilian ayahuasca religions Sandra Lucia Goulart Assistant Professor at Cásper Líbero College, São Paulo, Brazil and researcher in NEIP (Psychoactives Interdisciplinary Study Group), São Paulo, Brazil Abstract. This article discusses concepts and practices of healing in Brazilian religions which have in common the use of a psychoactive beverage mainly known by the names of Daime, Vegetal and Ayahuasca. These religions are elaborated from the same set of cultural traditions which nonetheless unfolds in different ways. All of them originate in the Brazilian Amazon region and in some cases, these processes expand to other parts of Brazil and abroad. We compare here the ways in which the healing is experienced and explained in these religions, emphasizing the representations concerning this beverage used in all of them. The case of these religions points to the complexity of the relation between both scientific and religious medicines. 1. Introduction In this article we intend to develop an analysis of the therapeutic concepts present in some religious cults emerged in the Brazilian Amazon region Correspondence/Reprint request: Dr. Sandra Lucia Goulart, Assistant Professor at Cásper Líbero College, São Paulo, Brazil and researcher in NEIP (Psychoactives Interdisciplinary Study Group), São Paulo, Brazil E-mail: [email protected] 24 Sandra Lucia Goulart starting from 1930. All these cults have in common the use of the same psychoactive beverage, made by brewing a combination of two plants, a liana whose scientific name is Banisteriopsis caapi and the leaves of a bush, Psychotria viridis1. -
Health Status of Ayahuasca Users Paulo Cesar Ribeiro Barbosa,A,B*Suelymizumoto,C Michael P
Drug Testing Review and Analysis Received: 6 February 2012 Revised: 15 May 2012 Accepted: 15 May 2012 Published online in Wiley Online Library (www.drugtestinganalysis.com) DOI 10.1002/dta.1383 Health status of ayahuasca users Paulo Cesar Ribeiro Barbosa,a,b*SuelyMizumoto,c Michael P. Bogenschutzc and Rick J. Strassmanb Ayahuasca is a psychedelic brew originally used for magico-religious purposes by Amerindian populations of the western Amazon Basin. Throughout the last four decades, the use of ayahuasca spread towards major cities in all regions of Brazil and abroad. This trend has raised concerns that regular use of this N,N-dimethyltryptamine- and harmala-alkaloid-containing tea may lead to mental and physical health problems associated typically with drug abuse. To further elucidate the mental and physical health of ayahuasca users, we conducted a literature search in the international medical PubMed database. Inclusion criteria were evaluation of any related effect of ayahuasca use that occurred after the resolution of acute effects of the brew. Fifteen publications were related to emotional, cognitive, and physical health of ayahuasca users. The accumulated data suggest that ayahuasca use is safe and may even be, under certain conditions, beneficial. However, methodological bias of the reviewed studies might have contributed to the preponderance of beneficial effects and to the few adverse effects reported. The data up to now do not appear to allow for definitive conclusions to be drawn on the effects of ayahuasca use on mental and physical health, but some studies point in the direction of beneficial effects. Additional studies are suggested to provide further clarification. -
The Purposes of History? Curriculum Studies, Invisible Objects and Twenty- first Century Societies
This may be the author’s version of a work that was submitted/accepted for publication in the following source: Baker, Bernadette (2013) The purposes of history? Curriculum studies, invisible objects and twenty- first century societies. Journal of Curriculum Theorizing, 29(1), pp. 25-47. This file was downloaded from: https://eprints.qut.edu.au/89916/ c The authors Individual non-commercial use only. Notice: Please note that this document may not be the Version of Record (i.e. published version) of the work. Author manuscript versions (as Sub- mitted for peer review or as Accepted for publication after peer review) can be identified by an absence of publisher branding and/or typeset appear- ance. If there is any doubt, please refer to the published source. http:// journal.jctonline.org/ index.php/ jct/ article/ view/ 409 FEATURE ARTICLE The Purposes of History? Curriculum Studies, Invisible Objects and Twenty- first Century Societies BERNADETTE BAKER University of Wisconsin-Madison N DECONSTRUCTING HISTORY, Alun Munslow (2006, p. 1) articulates what is now I commonplace, that “It is generally recognised that written history is contemporary or present orientated to the extent that we historians not only occupy a platform in the here-and-now, but also hold positions on how we see the relationship between the past and its traces, and the manner in which we extract meaning from them. There are many reasons, then, for believing we live in a new intellectual epoch – a so-called postmodern age – and why we must rethink the nature of the historical -
Downloaded Their Wisdom from the Ancient Sunken Library of the Atlantians
CHAPTER 13 THE BRIGHT DARKNESS-PERSO AL INSIGHTS INTO THE ENTHEOGENIC USE OF KETAMINE Julian Vayne My entheogenic explorations with the substance known as ketamine began when I was four years old. At that age, I suffered from an astigmatism af- fecting my left eye. This led to a planned admission to the hospital and an operation to correct the problem. The anesthetic used on me was ketamine, a drug commonly employed for surgery on children and the elderly (Couper et al., 2013). Ketamine is a very safe, reliable medicine (Jansen, 2004, p. 267) and also a medicine that can provoke strange visions, distortions of space and time, and even, 1 later discovered, open the door to peak spiritual experiences (Jansen, 2004<,p. 267). For years after this operation, two things haunted me: The first was a vision, a nightmare. Something that I'd see in dreams when under stress (1 was something of a worrisome child), during fevers, and sometimes in the hypnagogic or hypnopompic states. The vision was of an egg. Not a realistic object but a stylized black-and-white ovoid shape in a 2D space that filled my entire visual field. Bisected at the widest part of the figure, this egg would appear on a background of black and white. As the top of the egg shape was filled with black, so the field behind that part of the shape would switch to white, and vice versa, for the bottom of the egg. Then the picture would shift, the monochromatic shades switching around, faster and faster until the black seemed white and the white dark.