Hoarseness : Hoarseness Is It Serious?

Total Page:16

File Type:pdf, Size:1020Kb

Hoarseness : Hoarseness Is It Serious? HOARSENESS : HOARSENESS IS IT SERIOUS? IS IT SERIOUS ? Hoarseness is a symptom of dysfunction of the vocal folds! It is a very common symptom UNIVERSITY OF KENTUCKY It affects most of us somewhere Chandler Medical Center throughout our lives Sanford M. Archer, M.D. Professor of Surgery & Pediatrics OtolaryngologyOtolaryngology––HeadHead & Neck Surgery DISORDERS OF VOICE LISTENING TO YOUR PATIENT PRODUCTION Is there a weak or damped voice? Pulmonary disorders - Lungs Is the voice barely perceptible? Hoarseness - Laryngeal Are the lungs or pulmonary tree restricted in Art icu lat ion disord ers - OlOral movement? Does the patient have difficulty in articulating Resonance disorders - words? Oropharyngeal, Nasal Is the voice hyper/hypohyper/hypo--nasal?nasal? Are the sounds muffled? Are the words dysarthric? ETIOLOGY OF HOARSENESS The most common cause of hoarseness in my practice is NOT maliggy,ynancy, yet ... All adults who use tobacco and have persistent hoarseness of greater than 3 weeks duration have a malignancy until proven otherwise! Page 1 ETIOLOGY OF HOARSENESS Congenital causes Inflammatory causes Tumors Trauma Neurologic disorders Psychogenic disorders Other causes CONGENITAL CAUSES Congenital glottic webs Cysts Laryngomalacia Cri du chat TUMORS Benign Laryngeal papilloma Hemangioma Malignant Squamous cell carcinoma Thyroid carcinoma Others Page 2 Page 3 TRAUMA Vocal abuse External trauma Cho king Neck trauma (MVA, fisticuffs) Page 4 NEUROLOGIC DISORDERS Spasmodic dysphonia Benign essential tremor Vocal cord ppyaralysis Myasthenia gravis Muscular dystrophy CVA ALS Functional dysphonia/aphonia PSYCHOGENIC VOCAL CORD PARALYSIS VOICE DISORDERS Emotional Stress - (musculoskeletal tension ) Iatrogenic (neck, chest surgery) Voice Disorders w/o 2° Laryngeal Pathology Thyroid malignancy Voice Disorders w/ 2° Laryngeal Pathology Vocal nodule Thoracic lesions Contact ulcer Skull base tumors Psychoneurosis Conversion Reaction CV anomalies Mutism Laryngeal intubation/trauma Aphonia Dysphonia CNS anomalies Psychosexual Conflict Idiopathic Iatrogenic OTHER DISORDERS INFLAMMATORY CAUSES Smoking Hypothyroidism Foreign bodies Hormonal disorders Allergic angioneurotic edema Rhidhiiheumatoid arthritis Acute laryngitis (URI) Chronic laryngitis SLE Laryngopharyngeal reflux Polychondritis Contact ulcers, vocal nodules & polyps Dysphonia plicae ventricularis Amyloidosis Granulomatous diseases of the larynx Page 5 CHRONIC LARYNGITIS Smoking Vocal abuse Poor vocalhil technique Laryngopharyngeal reflux WORKUP OF PERSISTENT HOARSENESS LISTEN to the voice Nasal exam (signs of allergy, sinus) Oral(l exam (PND, pa late & tongue mobility) LOOK at the vocal folds Neck exam (muscle tension, masses, tracheal deviation, thyroid enlargement) ACUTE ONSET OF ONSET OF HOARSENESS HOARSENESS Acute URI Vocal abuse Chronic, intermittent IflInflamma tion Chronic, progressive Hemorrhage Page 6 CHRONIC, PROGRESSIVE SYMPTOMS Tumors Vocal nodules Vocal ppypolyps Spasmodic dysphonia Functional dysphonia Aging changes CHRONIC, RECURRING SYMPTOMS Neurologic disorders Tumors Laryngophlflharyngeal reflux Postnasal discharge (PND) REFLUX : REFLUX: Pathophysiology Pathophysiology – Critical Factors Normal Defensive Normal Aggressive LES tone Factors Factors Frequency and duration of transient LES tone Gastrin LES relaxations Anatomic factors Pepsin Esophageal clearing Bile acids Acidity of the gastric contents Mucosal resistance Pancreatic enzymes Amount of time acid is in the Gastric emptying Gastric acid esophagus/pharynx/larynx Volume of gastric material Page 7 RELAXATION OF THE LES MUCOSAL INJURY & pH Drugs Foods pH < 4.0 correlates highly with Calcium channel Caffeine severity of mucosal injury blockers Fatty foods pH > 4. 0 correlates with leveling off Anticholinergic Chocolate agents of symptoms Peppermint Narcotics Alcohol pH < 4.0 results in reduced ability for Estrogens mucosa to heal +/or repair itself Nitrates Others Smoking GASTROESOPHAGEAL REFLUX: GASTROESOPHAGEAL REFLUX : Symptoms Epidemiology Nighttime, supine symptoms are most common: Heartburn present in 11% of people daily Dyspepsia or indigestion - Most common symptom Symptoms present in 1/3 of population Heartburn everyyy 3 days Dysphagia 2/3 of people experience dyspepsia at some point in their lives Chest pain Prevalence of GERD-GERD-relatedrelated symptoms increases with age LARYNGOPHARYNGAL REFLUX: LARYNGOPHARYNGAL REFLUX : Symptoms Epidemiology Daytime, upright symptoms are most common: Incidence of 4 - 10% of patients Hoarseness - most common symptom Globus pharyngeus presenting to ORL practice Frequent throat clearing Incidence of 1% of pppatients presenting to Chronic cough primary care practice Dysphagia Frequent sore throats 2/3 of patients with laryngeal & voice Paroxysmal laryngospasm disorders have GERD as primary cause or Prolonged vocal warmwarm--upup significant cofactor Asthma 80% do not have dyspepsia ! Koufman, 1996 Page 8 LARYNGOPHARYNGAL REFLUX: Laryngeal Examination Mild to moderate vocal fold edema (reflux laryngitis) Laryngeal granulomas & contact ulcerations Vocal nodules Paroxysmal laryngospasm Hyperplasia of the interarytenoid space Erythema of the posterior larynx or pharynx Larygeal/subglottic stenosis LARYNGOPHARYNGAL REFLUX: Evaluation Videostroboscopy Barium esophagram Motility & peristalsis problems Tumors, diverticula , strictures Esophagitis Spontaneous reflux Hiatal hernia LES integrity 24 hr ambulatory pH monitoring of esophagus & pharynx Acid suppressive therapy TREATMENT OF CHRONIC LARYNGITIS & LPR LARYNGOPHARYNGEAL REFLUX 182/233 consecutive patients with chronic Lifestyle modifications laryngitis LPR Dietary restrictions Symptoms of persistent sore throat, PND Avoid late night snacks or meals w/ throat clearing, hoarseness, cough w/o pulmonary disease Tobacco use cessation Reduction of alcohol intake 96% of patients experienced relief of symptoms w/ treatment preventing reflux Elevation of head of bed of gastric acid Medical therapy Hanson et al, Ann Otol Laryngol 104; 1995 Page 9 OUTCOMES OF TREATMENT FOR LPR Outstanding results by those who recognize LPR and treat it effectively Need to educate other physicians and patients about LPR Must develop better methods to document causality of GER-GER-relatedrelated laryngeal disease GOOD VOCAL CARE SPEECH THERAPY Humidification Useful for : Warm mist vaporization Functional disorders Mucolytic agents Inflammatory disorders TtTreatmen tfllit of allergies Neurologic disorders Treatment of reflux laryngitis PrePre--surgicalsurgical evaluation Cessation of smoking and tobacco use Avoidance of vocal abuse such as yelling, screaming, and whispering Often, a course of vocal rest may be worthwhile REFERRAL TO OTOLARYNGOLOGIST Abnormal finding on physical exam Normal laryngeal exam with persistent hoarseness Inability to visualize the vocal folds or larynx Page 10 WHAT CAN WE DO? Mirror exam A smoker with persistent Flexible fiberoptic exam hoarseness of greater than Videostro boscopy* 3 weeks duration has a Recommend a Neurology referral malignancy until proven Early, quick feedback on YOUR otherwise. patient HOARSENESS IS IT SERIOUS? IT CERTAINLY CAN BE! Page 11.
Recommended publications
  • 1 British Thoracic Society Guidelines Recommendations for The
    Thorax Online First, published on September 28, 2007 as 10.1136/thx.2007.077370 Thorax: first published as 10.1136/thx.2007.077370 on 28 September 2007. Downloaded from British Thoracic Society Guidelines Recommendations for the assessment and management of cough in children MD Shields, A Bush, ML Everard, S McKenzie and R Primhak on behalf of the British Thoracic Society Cough Guideline Group Michael D Shields Dept. of Child Health, Queen’s University of Belfast, Clinical Institute, Grosvenor Road, Belfast, BT12 6BJ Email: [email protected] Andrew Bush Royal Brompton Hospital, Sydney Street, London, SW3 6NP Email: [email protected] Mark L Everard Dept of Paediatrics, Sheffield Children’s Hospital, Western Bank, Sheffield, S. Yorkshire, S10 2TH. Email: [email protected] Sheila McKenzie Queen Elizabeth Children’s Services, http://thorax.bmj.com/ The Royal London Hospital, Whitechapel, London, E1 1BB Email: [email protected] Robert Primhak Dept. of Paediatrics, Sheffield Children’s Hospital, on September 29, 2021 by guest. Protected copyright. Western Bank, Sheffield, S. Yorkshire, S10 2TH. Email: [email protected] “the Corresponding Author (Michael D Shields) has the right to grant on behalf of all authors and does grant on behalf of all authors, an exclusive licence (or non exclusive for government employees) on a worldwide basis to the BMJ Publishing Group Ltd and its Licensees to permit this article (if accepted) to be published in [THORAX] editions and any other BMJPG Ltd products to exploit all subsidiary rights, as set out in our licence 1 Copyright Article author (or their employer) 2007.
    [Show full text]
  • Complications of Different Ventilation Strategies in Endoscopic Laryngeal
    Anesthesiology 2006; 104:52–9 © 2005 American Society of Anesthesiologists, Inc. Lippincott Williams & Wilkins, Inc. Complications of Different Ventilation Strategies in Endoscopic Laryngeal Surgery A 10-year Review Yves Jaquet, M.D.,* Philippe Monnier, M.D.,† Guy Van Melle, M.D., Ph.D.,‡ Patrick Ravussin, M.D.,§ Donat R. Spahn, M.D., F.R.C.A.,࿣ Madeleine Chollet-Rivier, M.D.# Background: Spontaneous ventilation, mechanical controlled tracheal tube offers adequate airway protection and ventilation, apneic intermittent ventilation, and jet ventilation gas exchange, but the endotracheal tube prevents are commonly used during interventional suspension micro- optimal vision and access to the larynx. Furthermore, laryngoscopy. The aim of this study was to investigate specific 1–4 complications of each technique, with special emphasis on endotracheal fire may still be encountered with transtracheal and transglottal jet ventilation. the use of carbon dioxide laser despite the develop- Methods: The authors performed a retrospective single-insti- ment of nonflammable endotracheal tubes.5–7 tution analysis of a case series of 1,093 microlaryngoscopies 2. Spontaneous ventilation offers a free access to the performed in 661 patients between January 1994 and January larynx, but with a moving surgical field and a risk of 2004. Data were collected from two separate prospective data- bases. Feasibility and complications encountered with each inhalation of anesthetic gases and laser fumes by the technique of ventilation were analyzed as main outcome mea- patient
    [Show full text]
  • Diagnosis and Therapy for Airway Obstruction in Children with Down Syndrome
    ORIGINAL ARTICLE Diagnosis and Therapy for Airway Obstruction in Children With Down Syndrome Ron B. Mitchell, MD; Ellen Call, MS, CFNP; James Kelly, PhD Objectives: To document the causes of upper airway children had subglottic stenosis. Laryngomalacia was the obstruction in a population of children with Down syn- primary diagnosis in 10 children (43%), 8 of whom were drome and to highlight the role of associated comorbidi- younger than 1 month. Obstructive sleep apnea was the ties. primary diagnosis in 11 children (48%), 8 of whom were older than 2 years. All children with obstructive sleep ap- Design and Setting: Review of 23 cases involving chil- nea and 4 children with laryngomalacia had a second- dren with Down syndrome who were referred for upper ary ear, nose, and throat disorder. Gastroesophageal re- airway obstruction over a 21⁄2-year period to the Pediat- flux was a comorbidity in 14 children (61%). ric Otolaryngology Service of the University of New Mexico, Albuquerque. Conclusions: The causes, severity, and presentation of upper airway obstruction in children with Down syn- Methods: Data on the following variables were ob- drome are related to the age of the child and to associ- tained: reason for referral, demographics, diagnosis, sur- ated comorbidities. The treatment of comorbidities and gical procedures, complications, and comorbidities. secondary ear, nose, and throat disorders is an integral component of the surgical management of upper airway Results: The children ranged in age from 1 day to 10.2 obstruction in such cases. years (mean age, 1.8 years; median age, 6 months). Thir- teen children were male and 10 were female.
    [Show full text]
  • Supraglottoplasty Home Care Instructions Hospital Stay Most Children Stay Overnight in the Hospital for at Least One Night
    10914 Hefner Pointe Drive, Suite 200 Oklahoma City, OK 73120 Phone: 405.608.8833 Fax: 405.608.8818 Supraglottoplasty Home Care Instructions Hospital Stay Most children stay overnight in the hospital for at least one night. Bleeding There is typically very little to no bleeding associated with this procedure. Though very unlikely to happen, if your child were to spit or cough up blood you should contact your physician immediately. Diet After surgery your child will be able to eat the foods or formula that they usually do. It is important after surgery to encourage your child to drink fluids and remain hydrated. Daily fluid needs are listed below: • Age 0-2 years: 16 ounces per day • Age 2-4 years: 24 ounces per day • Age 4 and older: 32 ounces per day It is our experience that most children experience a significant improvement in eating after this procedure. However, we have found about that approximately 4% of otherwise healthy infants may experience a transient onset of coughing or choking with feeding after surgery. In our experience these symptoms resolve over 1-2 months after surgery. We have also found that infants who have other illnesses (such as syndromes, prematurity, heart trouble, or other congenital abnormalities) have a greater risk of experiencing swallowing difficulties after a supraglottoplasty (this number can be as high as 20%). In time the child usually will return to normal swallowing but there is a small risk of feeding difficulties. You will be given a prescription before you leave the hospital for an acid reducing (anti-reflux) medication that must be filled before you are discharged.
    [Show full text]
  • Stridor in the Newborn
    Stridor in the Newborn Andrew E. Bluher, MD, David H. Darrow, MD, DDS* KEYWORDS Stridor Newborn Neonate Neonatal Laryngomalacia Larynx Trachea KEY POINTS Stridor originates from laryngeal subsites (supraglottis, glottis, subglottis) or the trachea; a snoring sound originating from the pharynx is more appropriately considered stertor. Stridor is characterized by its volume, pitch, presence on inspiration or expiration, and severity with change in state (awake vs asleep) and position (prone vs supine). Laryngomalacia is the most common cause of neonatal stridor, and most cases can be managed conservatively provided the diagnosis is made with certainty. Premature babies, especially those with a history of intubation, are at risk for subglottic pathologic condition, Changes in voice associated with stridor suggest glottic pathologic condition and a need for otolaryngology referral. INTRODUCTION Families and practitioners alike may understandably be alarmed by stridor occurring in a newborn. An understanding of the presentation and differential diagnosis of neonatal stridor is vital in determining whether to manage the child with further observation in the primary care setting, specialist referral, or urgent inpatient care. In most cases, the management of neonatal stridor is outside the purview of the pediatric primary care provider. The goal of this review is not, therefore, to present an exhaustive review of causes of neonatal stridor, but rather to provide an approach to the stridulous newborn that can be used effectively in the assessment and triage of such patients. Definitions The neonatal period is defined by the World Health Organization as the first 28 days of age. For the purposes of this discussion, the newborn period includes the first 3 months of age.
    [Show full text]
  • Laryngomalacia: Disease Presentation, Spectrum, and Management
    Hindawi Publishing Corporation International Journal of Pediatrics Volume 2012, Article ID 753526, 6 pages doi:10.1155/2012/753526 Review Article Laryngomalacia: Disease Presentation, Spectrum, and Management April M. Landry1 and Dana M. Thompson2 1 Department of Otolaryngology, Head and Neck Surgery, Mayo Clinic Arizona, Phoenix, AZ 85054, USA 2 Division of Pediatric Otolaryngology, Department of Otorhinolaryngology, Head and Neck Surgery, Mayo Clinic Children’s Center and Mayo Eugenio Litta Children’s Hospital, Mayo Clinic Rochester, 200 First Street SW, Gonda 12, Rochester, MN 55905, USA Correspondence should be addressed to Dana M. Thompson, [email protected] Received 10 August 2011; Accepted 23 November 2011 Academic Editor: Jeffrey A. Koempel Copyright © 2012 A. M. Landry and D. M. Thompson. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Laryngomalacia is the most common cause of stridor in newborns, affecting 45–75% of all infants with congenital stridor. The spectrum of disease presentation, progression, and outcomes is varied. Identifying symptoms and patient factors that influence disease severity helps predict outcomes. Findings. Infants with stridor who do not have significant feeding-related symptoms can be managed expectantly without intervention. Infants with stridor and feeding-related symptoms benefit from acid suppression treatment. Those with additional symptoms of aspiration, failure to thrive, and consequences of airway obstruction and hypoxia require surgical intervention. The presence of an additional level of airway obstruction worsens symptoms and has a 4.5x risk of requiring surgical intervention, usually supraglottoplasty.
    [Show full text]
  • Series of Laryngomalacia, Tracheomalacia, and Bronchomalacia Disorders and Their Associations with Other Conditions in Children
    Pediatric Pulmonology 34:189-195 (2002) Series of Laryngomalacia, Tracheomalacia, and Bronchomalacia Disorders and Their Associations With Other Conditions in Children I.B. Masters, MBBS, FRACP,1* A.B. Chang, PhD, FRACP,2 L. Patterson, MBBS, FANZCAC,1 С Wainwright, MD, FRACP,1 H. Buntain, MBBS,1 B.W. Dean, MSC,1 and P.W. Francis, MD, FRACP1 Summary. Laryngomalacia, bronchomalacia, and tracheomalacia are commonly seen in pediatric respiratory medicine, yet their patterns and associations with other conditions are not well-understood. We prospectively video-recorded bronchoscopic data and clinical information from referred patients over a 10-year period and defined aspects of interrelationships and associations. Two hundred and ninety-nine cases of malacia disorders (34%) were observed in 885 bronchoscopic procedures. Cough, wheeze, stridor, and radiological changes were the most common symptoms and signs. The lesions were most often found in males (2:1) and on the left side (1.6:1). Concomitant malacia lesions ranged from 24%forlaryngotracheobronchomalaciato 47% for tracheobronchomalacia. The lesions were found in association with other disorders such as congenital heart disorders (13.7%), tracheo-esophageal fistula (9.6%), and various syndromes (8%). Even though the understanding of these disorders is in its infancy, pediatricians should maintain a level of awareness for malacia lesions and consider the possibility of multiple lesions being present, even when one symptom predominates or occurs alone. Pediatr Pulmonol Pediatr Pulmonol. 2002; 34:189-195. © 2002 wiiey-Liss. inc. Key words: laryngomalacia; tracheomalacia; bronchomalacia; malacia disorders; syndromes. INTRODUCTION The aim of this report is to describe an extensive experience of various forms of laryngomalacia, tracheo­ Tracheomalacia, bronchomalacia, and laryngomalacia malacia, and bronchomalacia and explore some of the disorders are commonly seen in tertiary pediatric respira­ interrelationships that exist between these conditions with tory practice.
    [Show full text]
  • ATS Technical Standards: Flexible Airway Endoscopy in Children
    AMERICAN THORACIC SOCIETY DOCUMENTS Official American Thoracic Society Technical Standards: Flexible Airway Endoscopy in Children Albert Faro, Robert E. Wood, Michael S. Schechter, Albin B. Leong, Eric Wittkugel, Kathy Abode, James F. Chmiel, Cori Daines, Stephanie Davis, Ernst Eber, Charles Huddleston, Todd Kilbaugh, Geoffrey Kurland, Fabio Midulla, David Molter, Gregory S. Montgomery, George Retsch-Bogart, Michael J. Rutter, Gary Visner, Stephen A. Walczak, Thomas W. Ferkol, and Peter H. Michelson; on behalf of the American Thoracic Society Ad Hoc Committee on Flexible Airway Endoscopy in Children THESE OFFICIAL TECHNICAL STANDARDS OF THE AMERICAN THORACIC SOCIETY (ATS) WERE APPROVED BY THE ATS BOARD OF DIRECTORS,JANUARY 2015 Background: Flexible airway endoscopy (FAE) is an accepted and Results: There is a paucity of randomized controlled trials in frequently performed procedure in the evaluation of children with pediatric FAE. The committee developed recommendations based known or suspected airway and lung parenchymal disorders. predominantly on the collective clinical experience of our committee However, published technical standards on how to perform FAE in members highlighting the importance of FAE-specific airway children are lacking. management techniques and anesthesia, establishing suggested competencies for the bronchoscopist in training, and defining areas Methods: The American Thoracic Society (ATS) approved the deserving further investigation. formation of a multidisciplinary committee to delineate technical standards for
    [Show full text]
  • Respiratory Concerns in Children with Down Syndrome
    Respiratory Concerns in Children with Down Syndrome Paul E. Moore, M.D. Associate Professor of Pediatrics and Pharmacology Director, Pediatric Allergy, Immunology, and Pulmonary Medicine Vanderbilt University School of Medicine Respiratory Concerns in Children with Down Syndrome • Overview • Respiratory infections • Airway issues • Sleep issues • Pulmonary vascular issues Respiratory Concerns in Children with Down Syndrome: Overview • Most common reason for children to be admitted to the hospital. • Respiratory infections can be more severe, and hospitalization often results in admission to the intensive care unit. Anatomical features in DS that contribute to respiratory concerns • Craniofacial features – Narrowed nasopharynx – Flattened mid-face – Macroglossia • Adenotonsillar hypertrophy • Airway size Other features of DS that contribute to respiratory concerns • Low tone (hypotonia) – Upper airway muscles: dysphagia – Airway: malacia • Gastroesophageal reflux – Contribution to adenotonsillar hypertrophy – Contribution to airway inflammation • Cardiac disease • Obesity Pearl #1: Anatomical features and physiologic contributors specific to Down Syndrome result in malacia • Definition: softening or loss of consistency in any of the organs or tissues • Origin: Greek malakía softness, tenderness, weakness • Laryngomalacia, tracheomalacia, bronchomalacia, airway malacia Respiratory Concerns in Children with DS: Respiratory Infections • Respiratory infection is a significant burden. – Bronchiolitis – URI/LRTI: upper respiratory infection and lower respiratory tract infection – Pneumonia Respiratory Concerns in Children with DS: Respiratory Infections • The specific defect in the immune system is not clear, although a number of studies suggest developmental delay. • Chronic aspiration is a significant contributor. Pearl #2: Developmental delay in Down Syndrome can refer to more than the nervous system. • Coordination of swallow • Immune development Pearl #3: Water (reflux) damage can be significant in children with DS.
    [Show full text]
  • Laryngomalacia
    Laryngomalacia Laryngomalacia (LAYR inn go mah LAY shah) is also called laryngeal stridor. It results from a weakness of parts of the voice box (larynx) that is present at birth. This condition can cause a high-pitched sound called stridor (STRI der). You may hear this sound when your child breathes in. Cause of Laryngomalacia Laryngomalacia means “soft larynx.” It is caused by floppiness of the tissue above the vocal cords (called the supraglottic larynx). When a person breathes in (inspiration), these tissues fall in towards the airway and cause the airway to be partly blocked. This blockage at the area of the voice box creates noisy breathing (called stridor). Picture 1 What laryngomalacia looks like in the body. Laryngomalacia is the most common cause of noisy breathing in infants. More than half of infants have noisy breathing during the first week of life. Most other babies have it within 2 to 4 weeks of birth. It is rare, but laryngomalacia can happen in older children or adults, usually those with other medical problems. HH-I-332 Revised 3/15 Copyright 2011, Nationwide Children’s Hospital Laryngomalacia Page 2 of 2 Signs and Symptoms The main symptom of laryngomalacia is noisy breathing when your child breathes in. This is called inspiratory stridor. Stridor may: . Change with activity. It may be louder when your child is upset, crying, or is excited. Be louder when your child has a cold. Usually it will be louder when your child is lying on his or her back, and quieter when he is lying on his stomach.
    [Show full text]
  • Chest Wall Abnormalities and Their Clinical Significance in Childhood
    Paediatric Respiratory Reviews 15 (2014) 246–255 Contents lists available at ScienceDirect Paediatric Respiratory Reviews CME article Chest Wall Abnormalities and their Clinical Significance in Childhood Anastassios C. Koumbourlis M.D. M.P.H.* Professor of Pediatrics, George Washington University, Chief, Pulmonary & Sleep Medicine, Children’s National Medical Center EDUCATIONAL AIMS 1. The reader will become familiar with the anatomy and physiology of the thorax 2. The reader will learn how the chest wall abnormalities affect the intrathoracic organs 3. The reader will learn the indications for surgical repair of chest wall abnormalities 4. The reader will become familiar with the controversies surrounding the outcomes of the VEPTR technique A R T I C L E I N F O S U M M A R Y Keywords: The thorax consists of the rib cage and the respiratory muscles. It houses and protects the various Thoracic cage intrathoracic organs such as the lungs, heart, vessels, esophagus, nerves etc. It also serves as the so-called Scoliosis ‘‘respiratory pump’’ that generates the movement of air into the lungs while it prevents their total collapse Pectus Excavatum during exhalation. In order to be performed these functions depend on the structural and functional Jeune Syndrome VEPTR integrity of the rib cage and of the respiratory muscles. Any condition (congenital or acquired) that may affect either one of these components is going to have serious implications on the function of the other. Furthermore, when these abnormalities occur early in life, they may affect the growth of the lungs themselves. The followingarticlereviewsthe physiology of the respiratory pump, providesa comprehensive list of conditions that affect the thorax and describes their effect(s) on lung growth and function.
    [Show full text]
  • 18Th International Congress of Pediatric
    PEDIATRIC PULMONOLOGY PEDIATRIC ISSN 8755-6863 VOLUME 54 , SUPPLEMENT 1 , JUNE 2019 PEDIATRIC PULMONOLOGY Volume Volume 54 • Supplement 18th International Congress of Pediatric Pulmonology Tokyo Chiba, June 27 – 30, 2019 1 • June 2019 2019 June Pages S1–S156 S1–S156 ONLINE SUBMISSION AND PEER REVIEW http://mc.manuscriptcentral.com/ppul PEDIATRIC PULMONOLOGY Volume 54 • Supplement 1 • June 2019 Proceedings S5 Foreword S6 Keynote Lecture S7 Plenary Sessions S22 Topic Sessions S75 Young Inves gator’s Oral Communica ons S81 Poster Sessions S149 Symposium Satellite OM Pharma S152 Index PEDIATRIC PULMONOLOGY Editor-in-Chief: THOMAS MURPHY, Boston, MA USA Deputy Editor: TERRY NOAH, Chapel Hill, NC USA Associate Editors: RICHARD AUTEN, Chapel Hill, NC USA ANNE CHANG, Brisbane, Queensland, Australia STEPHANIE DAVIS, Chapel Hill, NC USA HENRY DORKIN, Boston, MA USA BEN GASTON, Cleveland, OH USA ALEXANDER MOELLER, Zurich, Switzerland CLEMENT REN, Indianapolis, IN USA KUNLING SHEN, Beijing, China RENATO STEIN, Porto Alegre, Brazil PAUL STEWART, Chapel Hill, NC USA STEVEN TURNER, Aberdeen, Scotland, United Kingdom Topic Editors: JUDITH VOYNOW, Richmond, VA USA HEATHER ZAR, Cape Town, South Africa Managing Editor: MICHELLE BAYMAN, Hoboken, NJ USA Editorial Board Steven Abman Michael Fayon Larry Lands Francesca Santamaria Denver, CO USA Bordeaux, France Montreal, Canada Naples, Italy Avi Avital Shona Fielding Min Lu Gregory Sawicki Jerusalem, Israel Aberdeen, Scotland Shanghai, China Boston, MA USA Ian Balfour-Lynn Monika Gappa George B. Mallory, Jr.
    [Show full text]