Aug. 24, 1965 B. HONNET ETA 3,202,324 PLASTIC FOR INJECTABLE SOLUTIONS Filed Oct. 5, 962

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INVENTORS AEA/WAAPA) A/OW/WE7 A/EA2A2E MAA/E S/MOWE7 3,202,324 United States Patent Office Patented Aug. 24, 1965

2 material and comprises a top portion 1 wtih a tongue 2 3,202,324 PLASTC BAGS FOR NJECTABLE SOLUTIONS and an eyelet 3 (see FIG. 3), which fit into suspension Bernard Honnet and Pierre Marie Simonet, Paris, France, devices (not shown on the drawing), a main body 4 on assignors to Societe Francaise des Laboratoires Labaz which is shown the volume graduations 5, a lower por Societe Anonyme, Paris, France tion formed of rounded portions 6 and the plug device Filed Oct. 5, 1962, Ser. No. 228,575 7 into which are introduced the utilization and perfusion Claims priority, application France, Oct. 6, 1961, apparatus (not shown). A transverse section of the 875,220, Patent 1,310,582 may be circular, elliptical or oval, or may have a shape Claim. (Cl. 222-18) such as that shown in FIG. 2 in which a rectangular sec 0. tion is provided with semi-circular edge portions to de The present invention relates to bags made of synthetic fine a flattened cross-section. or so-called plastic materials which during the last few The bag according to the invention has the charac years have tended to replace the employed teristic feature that it is possible, by virtue of the changes for intravenous solutions, by reason of their advantages in radius of curvature of the lower portion 6, to obtain in respect of weight, volume, economy and safety. On 5 a bottom which is sufficiently deformable to be invagi the other hand however, these plastic bags have a num nated, i.e. able to be pushed back towards the interior, ber of drawbacks as compared with glass bottles: they as shown in FIG. 4. This arrangement enables the bag lack Stability and cannot remain standing upright; it is to rest on its bottom on a flat base and have the same difficult to add to the solution a substantial quantity of stability as a glass . medicinal solution; and it is impossible to read the quan 20 The bag is filled in this position with a predetermined tity injected because the bag flattens during use. quantity: 500 ml. or 1,000 ml. It can therefore be seen The invention has for its object to overcome these that in utilization it is possible to push back the concave drawbacks by means of a number of improvements which bottom 6 (FIG. 4) towards its convex or projecting posi may be applied conjointly or separately, if it is only re tion shown in FIG. 1; the displacement of the bottom quired to remedy one or other of the drawbacks referred 25 thus provides an increase in volume. It is then possible, to. either by means of the plug device 7 or by a special de A first improvement in accordance with the invention vice 8 described later, to add a quantity of solution equal consists in providing the bag of plastic material with a to the increased volume obtained by the deformation of base which is domed but which is sufficiently deformable the bottom of the . to be invaginable, i.e. able to be pushed back into the 30 The invention provides that this deformable wall, interior of the bag. In the first place, the bag can thus which has been described for the lower portion of the be placed on its bottom like a glass bottle, and secondly bag and in the vicinity of the plug device, may equally the increase in internal volume caused by the return of well be provided at the upper portion 9 of the bag in the the bottom to its domed position enables an equal vol vicinity of the neck 1 on which are fixed the Suspension ume of medicinal solution to be added to the original 35 members (not shown) as shown in FIG. 5. In the solution. invaginated position, the tongue 2 is folded back together A second improvement in accordance with the inven with the upper portion 1, on to the top 9. tion consists in providing the bag of plastic material with The bag in accordance with the invention may of a domed top which is similarly invaginable, thereby pro course be simultaneously provided with a deformable viding the same utilization of the increase in internal vol 40 ume when the top is returned to the domed position. bottom 6 (FIG. 4) and a deformable top 9 (FIG. 5). A third improvement according to the invention con The bag according to the invention may be provided, sists in providing the bag of plastic material with a de preferably at the upper portion, with a device 8 giving vice providing access to the interior space. This access access to the interior of the container. FIG. 1 shows this device is preferably provided at the upper portion, for device at the upper portion. The device comprises a example on the top, and is constituted by a spout used 45 spout which is projecting or recessed with respect to the on the one hand for the introduction of medicaments wall of the bag. This spout will preferably be employed into the bag and employed on the other hand so as to for the introduction of medicaments to the interior of permit the entry of air during utilization by means of a the bag, and also for the positioning of an air-inlet needle provided for that purpose. The bag is of course needle. In this latter , the interior of the bag during provided with a volumetric graduation, known perse, for 50 the course of perfusion of the solution will be in equilib direct reading of the quantities employed. rium with atmospheric pressure and will regain its geo The invention will be described with reference to FIGS. metrical form, even if part of the solution has passed out 1 to 5 of the accompanying drawings, given by way of through the spout 7. This method of ensuring perfusion example only and not in any limitative sense. In these - thus permits precise reading of the graduation 5 of the drawings: 5 5 bag. - - - FIG. 1 is a view in elevation of the bag in the position What we claim is: of use. A bag of flexible plastic material for containing a solu FIGS. 2 and 3 are cross-sections taken along the lines tion, said bag being constituted by a single piece of ma II-II and III-III of FIG. 1. terial defining a tubular body of flatted section with a FIG. 4 is a view in elevation of the bag with the bottom 60 base at each of opposite ends of said body, at least one invaginated. of said bases having curved surfaces and sufficient flexi FIG. 5 is a view in elevation of the bag with the top bility for being deformable between an invaginated posi invaginated. tion within said tubular body and a protruding position, As shown in FIG. 1, the bag in accordance with the said one base in the invaginated position thereof permit invention is constituted of a sheet of plastic synthetic ting the bag to be self standing, a sealed tongue on the 3,202,324 3 4. other of said bases including suspension means, said 1,663,664 3/28 Loomis ------222-92 X tongue being originally open and adapted for permitting 2,858,051 10/58 Cunningham ------222-105 X the introduction into said bag of said solution, said tongue 2,897,826 8/59 DiVito ------222-158 X being sealed after the solution has been introduced into 3,078,017 2/63 Waskonig et al. ------222-181 said bag, and discharge means on said one base for re 3,081,002 3/63 Tauschinski et al. ----- 222-105 moving the solution from said bag. LOUIS J. DEMBO, Primary Examiner. References Cited by the Examiner RAPHAEL M. LUPO, Examiner. UNITED STATES PATENTS Re. 24,251 12/56 Kaplan et al. ------222-107