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Atsuto Suzuki
Atsuto Suzuki (KEK : High Energy Accelerator Research Organization) 1 2 1. Quark Flavor Project 2. Lepton Flavor Project 3. Energy Frontier Project 4. Non-Accelerator Project 5. Summary 3 In 2008 4 Quest for International Linear Collider Quest for Unifying Birth-Evolution (ILC) Matter and Force of Universe Scientific Activities Beyond Standard Physics Lepton CP Asymmetry Technology Innovations Power-Upgrade Talented Human Resources SuperKEKB J-PARC KEK-B Quark CP Asymmetry LHC [Origin of Matter] nt Quest for Neutrinos nm Quest for 6 Quarks ne [Origin of Force] Higgs Particle [Origin of Mass] e-/e+ Collider KEKB -> SuperKEKB SCC RF(HER) Belle Detector 8 GeV e- 3.5 GeV e+ 1036 SuperKEKB Ares RF ) 1 - 50 times higher s cavity 2 - luminosity e+ source Peak Luminosity Luminosity (cm Peak TRISTAN 6 15 countries, 400 collaborators # of papers : 315 # of citations : 13,309 CPV: caused by a single phase of CKM matrix7 Standard Model X(3872) Z(4430) SM quar k lept on Bgdg transition BgD*tn Upgrade KEKB to SuperKEKB with x 50 performance 8 KEKB upgrade to SuperKEKB Colliding bunches IR with by*=0.3mm SC final focus system e-(2.6A) SuperKEKB Low emittance lattice Add RF systems for e+(3.6A) higher beam current Damping ring for low emittance positron injection Positron NEG pumps capture section LER beampipe to suppress photoelectron instability Beam SR Target: L = 8x1035/cm2/s 9 Belle II Detector (in comparison with Belle) EKLM Module 0 @ITEP Aerogel- RICH Bell SVD: 4 DSSD lyrs g 2 DEPFET lyrs + 4 DSSD lyrs CDC: small cell, long lever arm Bell II ACC+TOF g TOP+A-RICH ECL: waveform sampling (+pure CsI for end-caps) KLM: RPC g Scintillator +MPPC(end-caps) Inconsistency in unitarity triangle? B -> fKs J-PARC Facility (KEK/JAEA) Linac 3 GeV RCS Neutrino Beams (to Kamioka) Materials and Life Experimental Facility (n, m) Hadron Exp. -
Huda Y. Zoghbi, MD, Howard Hughes Medical Institute, Jan and Dan Duncan Neurological Research Institute at Texas Children’S Hospital and Baylor College of Medicine
Investigator Spotlight: Huda Y. Zoghbi, MD, Howard Hughes Medical Institute, Jan and Dan Duncan Neurological Research Institute at Texas Children’s Hospital and Baylor College of Medicine It is hard to believe that the 7th World Rett Syndrome Congress has come and gone with great success! Now with summer upon us, IRSF continues to move the spotlight to the committed scientists who have made the World Congress an impressive, high quality meeting with outstanding presentations and discussions. This month we are honored to focus on Dr. Huda Zoghbi who had co-chaired the Basic Research Symposium at the World Congress along with Dr. Gail Mandel. Together, they had produced an exciting lineup of speakers who were encouraged to present new, unpublished data in an effort to foster new ideas that will help chart the course for Rett syndrome research. Dr. Zoghbi is a Howard Hughes Medical Institute (HHMI) Investigator, the Director of the Jan and Dan Duncan Neurological Research Institute at Texas Children’s Hospital, and Professor of the Baylor College of Medicine in Houston, TX. She received her medical degree from Meharry Medical College and completed residency training in pediatrics and neurology at Baylor College of Medicine where she encountered her first Rett syndrome patient in 1983. Dr. Zoghbi was inspired to receive additional research training in the area molecular genetics and upon completion she joined the faculty of Baylor College of Medicine. In 1999, Dr. Zoghbi and collaborators including research fellow Ruthie Amir made a major breakthrough for Rett syndrome. They had discovered that mutations in MECP2, the gene encoding methyl-CpG-binding protein 2, causes Rett syndrome. -
UC San Diego UC San Diego Electronic Theses and Dissertations
UC San Diego UC San Diego Electronic Theses and Dissertations Title Spinocerebellar Ataxia Type 7 is Characterized by Defects in Mitochondrial and Metabolic Function Permalink https://escholarship.org/uc/item/02b7m809 Author Ward, Jacqueline Marie Publication Date 2016 Supplemental Material https://escholarship.org/uc/item/02b7m809#supplemental Peer reviewed|Thesis/dissertation eScholarship.org Powered by the California Digital Library University of California UNIVERSITY OF CALIFORNIA, SAN DIEGO Spinocerebellar Ataxia Type 7 is Characterized by Defects in Mitochondrial and Metabolic Function A dissertation submitted in partial satisfaction of the requirements for the degree Doctor of Philosophy in Biomedical Sciences by Jacqueline Marie Ward Committee in charge: Professor Albert La Spada, Chair Professor Eric Bennett Professor Lawrence Goldstein Professor Alysson Muotri Professor Miles Wilkinson 2016 Copyright Jacqueline Marie Ward, 2016 All rights reserved The Dissertation of Jacqueline Marie Ward is approved, and it is acceptable in quality and form for publication on microfilm and electronically: Chair University of California, San Diego 2016 iii DEDICATION This work is dedicated to my grandfather, Dr. Wayne Ward, the kindest person I’ve ever known. His memory inspires me to be a better person daily. iv TABLE OF CONTENTS SIGNATURE PAGE .......................................................................................... iii DEDICATION .................................................................................................. -
Program Book
PARKINSON’SDISEASE2014 ADVANCING RESEARCH, IMPROVING LIVES PROGRAM MATERIALS Sponsored by: January 6 – 7, 2014 Natcher Conference Center National Institutes of Health Bethesda, MD About our cover: The program cover image is a stylized version of the Parkinson’s Disease Motor-Related Pattern (PDRP), an abnormal pattern of regional brain function observed in MRI studies which shows increased metabolism indicated by red in some brain regions (pallidothalamic, pontine, and motor cortical areas), and decreased metabolism indicated by blue in others (associated lateral premotor and posterior parietal areas). Original image used with permission of David Eidelberg, M.D. For further information see: Hirano et al., Journal of Neuroscience 28 (16): 4201-4209. Welcome Message from Dr. Story C. Landis Welcome to the National Institute of Neurological Disorders and Stroke (NINDS) conference, “Parkinson’s Disease 2014: Advancing Research, Improving Lives.” Remarkable new discoveries and technological advances are rapidly changing the way we study the biological mechanisms of Parkinson’s disease, identify paths to improved treatments, and design effective clinical trials. Elucidating mechanisms and developing and testing effective interventions require a diverse set of approaches and perspectives. The NINDS has organized this conference with the primary goal of seeking consensus on, and prioritizing, research recommendations spanning clinical, translational, and basic Parkinson’s disease research that we support. We have assembled a stellar and dedicated group of session chairs and panelists who have worked collaboratively to identify emerging research opportunities in Parkinson’s research. While we have divided our working groups into three main research areas, we expect each will inform the others over the course of the next two days, and we look forward to both complementary and unique perspectives. -
Huda Zoghbi: Taking Genetic Inquiry to the Next Level
Spectrum | Autism Research News https://www.spectrumnews.org NEWS, PROFILES Huda Zoghbi: Taking genetic inquiry to the next level BY RACHEL ZAMZOW 25 JUNE 2021 Listen to this story: Most mornings, Huda Zoghbi, 67, climbs a glass-encased, curling staircase to reach her lab on the top and 13th floor of the Jan and Dan Duncan Neurological Research Institute in Houston, Texas. The twisting glass tower, which she designed with a team of architects, echoes the double helix of DNA — a structure that has been central to her career-long quest to uncover genes underlying neurological conditions. As the institute’s director — and as a scientist— she is known for going beyond the standard job description. Genetics researchers often cast a wide net and sequence thousands of genes at a time. But in her prolific career, Zoghbi has focused on a handful of genes, methodically building up an understanding of their function one careful step at a time. Thanks to that approach, Zoghbi has made a number of landmark discoveries, including identifying the genetic roots of Rett syndrome, an autism-related condition that primarily affects girls, as well as the genetic mutations that spur spinocerebellar ataxia, a degenerative motor condition. She has authored more than 350 journal articles. Her accomplishments have earned her almost every major biology and neuroscience research award, including the prestigious Breakthrough Prize in 2017 and the Brain Prize in 2020. “She’s clearly the international leader in the field,” said the late Stephen Warren, professor of human genetics at Emory University in Atlanta, Georgia. Zoghbi never set out to lead a large research center, she says — her heart is in the lab. -
2016 Joint Meeting Program
April 15 – 17, 2016 Fairmont Chicago Millennium Park • Chicago, Illinois The AAP/ASCI/APSA conference is jointly provided by Boston University School of Medicine and AAP/ASCI/APSA. Meeting Program and Abstracts www.jointmeeting.org www.jointmeeting.org Special Events at the 2016 AAP/ASCI/APSA Joint Meeting Friday, April 15 Saturday, April 16 ASCI President’s Reception ASCI Food and Science Evening 6:15 – 7:15 p.m. 6:30 – 9:00 p.m. Gold Room The Mid-America Club, Aon Center ASCI Dinner & New Member AAP Member Banquet Induction Ceremony (Ticketed guests only) (Ticketed guests only) 7:00 – 10:00 p.m. 7:30 – 9:45 p.m. Imperial Ballroom, Level B2 Rouge, Lobby Level How to Solve a Scientific Puzzle: Speaker: Clara D. Bloomfield, MD Clues from Stockholm and Broadway The Ohio State University Comprehensive Cancer Center Speaker: Joe Goldstein, MD APSA Welcome Reception & University of Texas Southwestern Medical Center at Dallas Presidential Address APSA Dinner (Ticketed guests only) 9:00 p.m. – Midnight Signature Room, 360 Chicago, 7:30 – 9:00 p.m. John Hancock Center (off-site) Rouge, Lobby Level Speaker: Daniel DelloStritto, APSA President Finding One’s Scientific Niche: Musings from a Clinical Neuroscientist Speaker: Helen Mayberg, MD, Emory University Dessert Reception (open to all attendees) 10:00 p.m. – Midnight Imperial Foyer, Level B2 Sunday, April 17 APSA Future of Medicine and www.jointmeeting.org Residency Luncheon Noon – 2:00 p.m. Rouge, Lobby Level 2 www.jointmeeting.org Program Contents General Program Information 4 Continuing Medical Education Information 5 Faculty and Speaker Disclosures 7 Scientific Program Schedule 9 Speaker Biographies 16 Call for Nominations: 2017 Harrington Prize for Innovation in Medicine 26 AAP/ASCI/APSA Joint Meeting Faculty 27 Award Recipients 29 Call for Nominations: 2017 Harrington Scholar-Innovator Award 31 Call for Nominations: George M. -
A Profile of Maharashtra S V Kogekar
THE ECONOMIC WEEKLY SPECIAL NUMBER JUNE 1960 plus. It is here that her policy of been distributed among all sec to launch a movement for the Pun non-alignment is an essential pre tions of the middle-class; at any rate jabi Suba, the vote in Calcutta's condition for India's democracy. For it cart never be so distributed as to South West Constituency or the Mani- non-alignment is another name for be considered "fair"' by all. Certain pur People's struggle for responsi alignment with both the Big Powers. sections of the middle-class due to ble government are ominous signs In fact, the role of the elite the early English education or their pro of the dangers inherent in building technique of development and foreign ximity to the political and financial up a middle-class-dominated society. policy are closely inter-connected capitals of India have attained a While, therefore, India may have and together hold the structure of higher standard among the middle- politics in India. It is not possible class. They now demand the conti ample breathing time, thanks to a to hold on to one and dispense with nuation of those privileges as a combination of circumstances, it the others. matter of right while new sections would be both risky and futile to are coming up to press for their sta postpone agrarian reorganisation un CONFLICT WITHIN MIDDLE CLASS tus as is evident from the acrimo duly long. The present advantages Two questions, however, still re nious Hindi-English controversy. afford us the opportunity to intro main to be answered. -
An Eye to the Future Advances in Imaging Are Accelerating the Pace of Biological Discovery
fall 2007 An Eye to the Future Advances in imaging are accelerating the pace of biological discovery. A new cellular imaging initiative at the University has researchers seeing small and thinking big. story on page 8 p r o f i l e s college News c l a s s N o t e s from the dean Where curiosity- and solution- driven science meet ome scientists are driven by a curiosity to under- As a curiosity-driven college, it’s CBS’ job to keep S stand how life works—from molecules to eco- adding to the foundation of knowledge that supports systems—and to add to the world’s collective body of translational and solution-driven science in other col- knowledge. Others are searching for a puzzle piece leges. As such, we are the stewards of the foundational that may yield a better way to treat cancer, produce disciplines in the biological sciences: biochemistry, food or create renewable forms of energy. molecular biology, genetics, cell biology and develop- ment, ecology, plant biology, etc. Both are essential, and there is plenty of overlap Robert Elde, Dean between the two. Curiosity-driven research often turns In order to keep fueling translational and solution- up a bit of information that has immediate applications driven research, we need to infuse foundational disci- in medicine, agriculture or engineering. By the same plines with new technologies and other opportunities token, solution-driven research can add to knowledge. as science evolves. And some scientists travel between these two worlds. Fall 07 Vol. 5 No. 3 Cellular imaging, the subject of our cover story, is one As a whole, College of Biological Sciences faculty of those opportunities. -
Annual Plan 2009-10
INDEX ANNUAL PLAN 2014-15 PART-I Chapter Subject Page No. No. Section – I General 1 Annual Plan 2014-15 – At a Glance 1-3 2 Economic Outline of Maharashtra 4-6 3 Planning Process 7-12 4 Central Assistance/Institutional Finance External Aided 13-17 Projects 5 Decentralization of Planning (District Planning) 18-20 6 Schedule Caste Sub-Plan 21-24 7 Tribal Sub Plan 25-28 8 Statutory Development Boards and Removal of Backlog 29-35 9 Woman and Child Development 36-42 10 Western Ghat and Hilly Area Development Programme 43-47 11 Human Development Index 48-50 Section 2 Sector wise 1 Agriculture and Allied Services 1-55 2 Rural Development 56-62 3 Special Area Development Programme 63 4 Water Resources and Flood Control 64-65 5 Power Development 66-79 6 Industry and Mining 80-94 7 Transport and Communication 95-102 8 Science, Technology and Environment 103-111 9 General Economic Services 112-125 10 Social and Community Services 126-237 11 General Services 238-246 ANNUAL PLAN 2014-15 AT A GLANCE Introduction: 1.1.1 Preparation and implementation of Five Year Plans and Annual Plans is one of the most important instruments for General Economic Development of the State. The main objective of planning is to create employment opportunities, improve standard of living of the people below the poverty line, and attain self-reliance and creation to infrastructure. 1.1.2 Size of Eleventh Five Year Plan (2007-12) was determined at Rs.1,27,538/- crore. However, sum of the Annual Plans from year 2007-08 to 2011-12 sanctioned by the Planning Commission arrived actually at Rs.1,61,124/- crore. -
14. Formation of State of Maharashtra
14. Formation of State of Maharashtra After India gained independence, there was demand on large scale for the reconstruction of states on linguistic basis. In Maharashtra also the demand for state of Marathi speaking people led to ‘Samyukta Maharashtra Movement’ from 1946 onwards. Through various changing circumstances the movement progressed and finally on 1 May 1960 the state of Maharashtra came to be formed. Background : From the beginning of 20th century, many scholars had begun to express the thoughts on unification of Marathi speaking people. In 1911, the British Government had to suspend the partition of Bengal. On this background, N.C.Kelkar wrote that ‘the entire Marathi speaking poulation should be under one dominion’. In 1915, Lokmanya Tilak had demanded the reconstruction of a state based on language. But during that period the issue of independence of India was more important, hence this issue remained aside. On 12 May 1946, in the Sahitya Sammelan at Belgaon, an important resolution regarding Samyukta Maharashtra was passed. Samyukta Maharashtra Parishad : On 28 July, ‘Maharashtra Ekikaran Parishad’ was called at Mumbai. Shankarrao Dev was its president. It passed a resolution that all Marathi speaking regions should be included in one state. This should also include Marathi speaking regions of Mumbai, Central provinces as well as Marathwada and Gomantak. Dar Commission : On 17 June 1947, Dr. Rajendra Prasad, the President of Constituent Assembly established the ‘Dar Commission’ under the chairmanship of Justice S.K.Dar, for forming linguistic provinces. On 10 December 1948, the report of Dar Commission was published but the issue remained unsolved. -
Self Study Report of SHREEMATI NATHIBAI DAMODAR THACKERSEY ARTS and COMMERCE COLLEGE for WOMEN, PUNE
Self Study Report of SHREEMATI NATHIBAI DAMODAR THACKERSEY ARTS AND COMMERCE COLLEGE FOR WOMEN, PUNE- SELF STUDY REPORT FOR 3rd CYCLE OF ACCREDITATION SHREEMATI NATHIBAI DAMODAR THACKERSEY ARTS AND COMMERCE COLLEGE FOR WOMEN, PUNE- SNDT ARTS AND COMMERCE COLLEGE FOR WOMEN, MAHARSHI KARVE VIDYA VIHAR, KARVE ROAD, PUNE 411038 www.sndtarts.ac.in Submitted To NATIONAL ASSESSMENT AND ACCREDITATION COUNCIL BANGALORE November 2020 Page 1/116 20-05-2021 04:11:24 Self Study Report of SHREEMATI NATHIBAI DAMODAR THACKERSEY ARTS AND COMMERCE COLLEGE FOR WOMEN, PUNE- 1. EXECUTIVE SUMMARY 1.1 INTRODUCTION The SNDT Arts and Commerce College for Women is the first women's college in South-East Asia. It was founded by Bharatratna Maharshi Dhondo Keshav Karve on 5 July 1916, with five students. This College is the Parent Institution of the SNDT Women’s University, Mumbai. Today, it functions as a Constituent College of this University. It is situated in the Pune campus of SNDT Women's University at Karve Road, Pune. The vision of the great social reformer, Bharatratna Maharshi Dhondo Keshav Karve, was translated into reality by the foundation of this College. With this College, he founded Indian Women's University. With generous support from Sir Vitthaldas Thackersey, an industrialist with social orientation, this University was named as Shreemati Nathibai Damodar Thackersey (SNDT) Women’s University, in the year 1920. The head office of the University was shifted to Mumbai in 1936. In the year 1951, the University acquired statutory recognition from the Government of Maharashtra along with the rare privilege of jurisdiction across the country. -
Submitted Proposal
Trimmed version of the CNAP PFC proposal to the NSF (page numbers refer to those in the upper right-hand corners) 1 NSF coverpage 2 Project Summary 3 Executive Summary 6 Prior Accomplishments 11 Major Activities Introduction 13 MA1: Neutrino Phenomenology 21 MA2: Neutrino Technology 31 MA3: Neutrino Frontier 41 Education, Development and Outreach 44 Shared Facilities 47 Collaboration with other sectors 49 International Collaboration 50 Seed Funding and Emerging Areas 51 Management 55 Institutional and Other Commitments 56 NSF Summary Table 57 References 64 Abbreviated Biographical Information 73 Center Budget Justification 81 Letter from NC Museum of Natural Sciences 82 List of Supporting Letters 1 COVER SHEET FOR PROPOSAL TO THE NATIONAL SCIENCE FOUNDATION PROGRAM ANNOUNCEMENT/SOLICITATION NO./CLOSING DATE/if not in response to a program announcement/solicitation enter NSF 08-1 FOR NSF USE ONLY NSF 07-567 01/30/08 NSF PROPOSAL NUMBER FOR CONSIDERATION BY NSF ORGANIZATION UNIT(S) (Indicate the most specific unit known, i.e. program, division, etc.) PHY - PHYSICS FRONTIER CENTER DATE RECEIVED NUMBER OF COPIES DIVISION ASSIGNED FUND CODE DUNS# (Data Universal Numbering System) FILE LOCATION 003137015 EMPLOYER IDENTIFICATION NUMBER (EIN) OR SHOW PREVIOUS AWARD NO. IF THIS IS IS THIS PROPOSAL BEING SUBMITTED TO ANOTHER FEDERAL TAXPAYER IDENTIFICATION NUMBER (TIN) A RENEWAL AGENCY? YES NO IF YES, LIST ACRONYM(S) AN ACCOMPLISHMENT-BASED RENEWAL 546001805 NAME OF ORGANIZATION TO WHICH AWARD SHOULD BE MADE ADDRESS OF AWARDEE ORGANIZATION, INCLUDING