Annual Report 2020 2021 Table of Contents

Total Page:16

File Type:pdf, Size:1020Kb

Annual Report 2020 2021 Table of Contents ANNUAL REPORT 2020 2021 TABLE OF CONTENTS • Mission, vision and goals 3 • Platelet Immunobiology Working Party 26 • Foreword from the President 4 • Quality Management Working Party 27 • Foreword from the Secretary General 6 • Rare Donor Working Party 29 • Board of Directors 7 • Red Cell Immunogenetics and Blood Group Terminology 30 • Membership 2020-2021 8 Working Party • Report from the Young Professionals Council 9 • Transfusion Transmitted Diseases Working Party 32 • Financial Summary 10 • Reports from ISBT Standing Committees 35 • Congresses 11 • ISBT Standing Committee of the ISBT Academy 36 • Reports from ISBT Working Parties 12 • ISBT Standing Committee on Ethics 39 • Blood Supply Management Working Party 13 • ISBT Standing Committee on Jean Julliard Prize 40 • Cellular Therapy Working Party 15 • ISBT Standing Committee of Vox Sanguinis 42 • Clinical Transfusion Working Party 16 • Report from Vox Sanguinis 43 • Donors and Donation Working Party 18 • Report from the ISBT Science Series 45 • Global Blood Safety Working Party 19 • Report from ISBT Foundation 47 • Granulocyte Immunobiology Working Party 21 • ISBT Award and Prizes 48 • Haemovigilance Working Party 22 • Immunohaematology Working Party 24 • Information Technology Working Party 25 Corporate Partners ISBT is pleased to acknowledge the following Corporate Partners during 2020-2021 2 2020-2021 Annual Report MISSION, VISION AND GOALS The International Society of Blood Transfusion (ISBT) is a scientific society that was founded in 1935. Since that time the ISBT has grown in to an international society where transfusion medicine professionals from across the globe come together and do the one thing they do best: share knowledge to improve the safety of blood transfusion worldwide. STRATEGIC GOALS The new goals, agreed as part of a 5-year strategic plan for 2020-2024, are designed to keep, and build upon those things we do well and to address areas where we feel we can improve. Education & Knowledge Be the global ‘go to’ organisation for transfusion medicine education, and knowledge sharing VISION Training and implementation of knowledge Be the leader in transforming knowledge into practice A world of safe and sufficient blood International outreach Engage transfusion medicine professionals and institutions globally Congress Be the international congress of choice for transfusion medicine professionals MISSION Publications ISBT is a global community of professionals sharing Be respected for high-quality scientific and professional publications knowledge to enhance transfusion practice. We do this by: Digital Resources Providing opportunities for advancing knowledge and education & by advocacy for the welfare of blood donors and patients. Be a trusted ‘go to’ source for information and interaction in all aspects of transfusion medicine Working parties Support Working Party activities to achieve outputs aligned with the ISBT strategy Governance Be recognized for transparent and sustainable governance Advocacy Be the advocate for blood donors and patients 3 2020-2021 Annual Report FOREWORD FROM THE PRESIDENT It is a pleasure and a privilege to write this foreword to the ISBT Annual Report It was with great disappointment that we had to cancel the in person aspects for 2020-21. of the congresses planned for Barcelona and Milan due to the ongoing pan- demic. ISBT congresses are a highlight of our society, and keenly anticipated What an extraordinary year this has been! In large part due to the SARS- each year! CoV-2 pandemic, wherever we are around the world we have experienced ma- jor changes to our lives, activities and plans. Many people have been directly However, it was simply not safe or possible to continue with our previous affected by illness, with others taking care of people in their professional roles plans. I thank all the members of the local organising committees for their or by caring for family and friends. Many others have experienced separation hard work on our behalf, and we look forward to rescheduling our congresses due to ‘lockdowns’ and travel disruptions. We remember with fondness and in those cities. respect those we have lost during this time. We were very pleased with the successful ISBT congress held online in ISBT has responded to COVID-19 with provision of expertise at country level December 2020. This could not have happened without excellent teamwork and internationally, through our Working Parties and our members’ individual and cooperation from the ISBT Central Office team, MCI (our professional and institutional networks, supported by our team in the Central Office. congress organiser), our Scientific Secretary and two Vice-Presidents, and all the speakers, abstract presenters, sponsors and our Corporate Partners. We quickly developed new COVID-19 resources and hosted a wide range of reference materials on our website. Our educational webinars were well But what a huge achievement! It was a great pleasure to welcome participants attended and a great way to disseminate new information as it became avai- to this new experience for ISBT. lable. Our Working Parties took on new activities to share ideas, experiences The program was high-quality and diverse, and there was active discussion and results, and to facilitate international cooperation in donor management, through the platform, including an online closing party! Personal highlights for clinical and laboratory transfusion practice, and research. me included the virtual award presentations, the re-launch of “Beryl’s book These have been highly productive, including developing new collaborations Introduction to Blood Transfusion: From Donor to Recipient” and the and producing multiple peer-reviewed publications. I thank everyone who has Young Professionals “breakfast” session. contributed to these activities. Despite the impact of COVID-19, ISBT has maintained its core program of work, even as we have learned to do some things differently. We welcomed We have also seen an enormous surge of research activity, with remarkable mobilisation of resources for studies of the prevention and diagnosis of SARS- our new Board of Directors in June 2020, who are working very productively CoV-2 infection and the care of people with COVID-19. together. I thank the previous Board for all their contributions to the work of the Society, and particularly Martin Olsson, now ISBT Past-President, for his Many of our members have played central roles in these activities, including great leadership and ongoing support. During 2021 we have been focussed research investigating the potential role of convalescent plasma to treat this on delivering on our Strategic Plan and adapting as needed to meet our goals condition, and by providing advice to policy-makers in government and other in these challenging times. organisations. I thank you all for your amazing efforts. 4 2020-2021 Annual Report FOREWORD FROM THE PRESIDENT We are ably supported by our Executive Director, Jenny White, and our de- We are also very grateful for the support of our Corporate Partners, whose dicated Central Office team. We thank them all – especially given the extra commitments enable ISBT to continue our work on a solid foundation, and who challenges in working from home for over a year! We are investing in our contribute valuable scientific and technical expertise to a range of activities, team through improved pension arrangements and will prioritise professional including via the Working Parties. development opportunities as working arrangements permit in the coming year. Behind the scenes we are also investing in our operational IT platforms Our many collaborations are flourishing, including via activities conducted including for communication, education and membership management. We with ISBT affiliate members, professional societies, other organisations and will see these come to fruition over the next year. via our long-term partnership with the World Health Organization as a non-go- vernmental organisation in official relations since 1955. To highlight just a few, during 2020-21 we have contributed to haemovigilance workshops in Africa We have also expanded our social media presence, including on Twitter, Ins- in support of the African Blood Regulators Forum, and to development of tagram, LinkedIn and Facebook – so please get in touch online! educational modules on the clinical use of blood. In this extraordinary year, we have had some new opportunities and succes- ses, and as president I am grateful to be able to share them with you. I hope you will enjoy reading this Annual Report. The ISBT Academy, Working Parties, Standing Committees, ISBT Founda- tion, Young Professionals Council and Transfusion Practitioners network are all actively contributing to ISBT’s success, and I encourage you to read more about them in this report. I particularly thank the chairs of these groups for their enthusiasm and leadership of the ‘engine rooms’ of the society. Our publications are widely read and flourishing, and I thank Dana Devine as editor of Vox Sanguinis, and Pieter van der Meer, editor of ISBT Science Series, for their contributions. Dana Devine stepped down during this year, transferring Vox to the capable hands of Miquel Lozano. 5 2020-2021 Annual Report FOREWORD FROM THE SECRETARY GENERAL The unusual circumstances of the COVID 19 pan- tings and working from home. The financial contribution to ISBT by the journal demic resulted in postponement of the usual June remains strong. international congress and eventually, as the travel
Recommended publications
  • Transfusion Service, Massachusetts General Hospital, Harvard Medical School, Boston Editor, Transfusion Medicine Reviews Financial Disclosure
    The Present and Future of Medical Publication Sunny Dzik, MD Blood Transfusion Service, Massachusetts General Hospital, Harvard Medical School, Boston Editor, Transfusion Medicine Reviews Financial Disclosure: Stipend from Elsevier Publishing for my role as Editor of Transfusion Medicine Reviews. I have no other conflicts of interest to declare. For 20 centuries In the 15th Century Moveable type ! 1450 Source: wikipedia Henry Oldenburg 1st Scientific Editor Introduced the idea of scientific peer review Source: insights.uksg.org For 20 centuries In the 15th Century Now 1450 The Internet is changing all aspects of medical publication 1. Business model for publishers. 2. Metrics to ”rank” scientific publication. 3. Opportunity for fraud, plagiarism & the ability to catch it. 4. Dimensions of information transfer. 5. Sheer volume of information and importance of quality. 1. Business Models for Medical Publication Individual subscription model becoming extinct. Publishers sell a ‘bundle’ of journal titles to libraries. Users access individual articles on line. Packaging articles in “volumes” with “page numbers” may seem increasingly out-of-date.* *DOI = digital object identifier How Medical Libraries Used to Store Articles Medical College Library in Tanzania kcmuco.ac.tz/home/ ‘Open Access’ publishing . Article is made freely available to all online immediately after acceptance. Author, Institution, or Grant Funds pay an ‘article publication fee’. Some journals publish exclusively open access (PLOS, Biomed Central). Most journals are mix of subscription and open access options. Open access can offset subscription costs. Devised at the University of Leiden Vox Sanguinis: Open access $3300 Free self-archive access after 12 months Transfusion: Open access $3900 Free self-archive access after 12 months Transfusion Medicine Reviews: Open access $2500 Free self-archive access after 12 months Globally: Funders Embrace Open Access (but usually do not pay for it) Image courtesy of Elsevier 2.
    [Show full text]
  • Which Is the Preferred Blood Product for Fibrinogen Replacement in The
    SUPPLEMENT ARTICLE Which is the preferred blood product for fibrinogen replacement in the bleeding patient with acquired hypofibrinogenemia— cryoprecipitate or fibrinogen concentrate? Melissa M. Cushing ,1 Thorsten Haas,2 Keyvan Karkouti,3,4 and Jeannie Callum5,6,7 PRO FIBRINOGEN CONCENTRATE: The importance of the targeted treatment of acquired FIBRINOGEN CONCENTRATE IS THE hypofibrinogenemia during hemorrhage with a PREFERRED BLOOD PRODUCT FOR concentrated fibrinogen product (either cryoprecipitate or FIBRINOGEN REPLACEMENT IN THE fibrinogen concentrate) cannot be underestimated. BLEEDING PATIENT WITH ACQUIRED Fibrinogen concentrate is a pathogen inactivated, pooled HYPOFIBRINOGENEMIA product that offers a highly purified single factor concentrate. Cryoprecipitate is a pooled product that hrough this section of our debate, we will attempt comes with a spectrum of other coagulation factors to convince you to abandon cryoprecipitate (if you which may further enhance (additional procoagulant have not already done so) for the management of effect) or even disturb (prothrombotic risk) hemostasis. hemorrhage in the presence of acquired hypo- Tfibrinogenemia (fibrinogen level less than 1.5-2.0 g/L). It is The pros and cons of each product are discussed. crucial for the safety of future generations of transfusion recip- ients that all blood products transfused are pathogen inactivated (where available, safe, and effective).1 Although there are numerous hurdles to the implementation of pathogen-inactivation technologies across all manufactured blood products
    [Show full text]
  • 19 Respiratory Illness (CONCOR-1): Study Protocol for an International, Multicenter, Randomized, Open- Label Trial
    Convalescent plasma for adults with acute COVID- 19 respiratory illness (CONCOR-1): Study protocol for an international, multicenter, randomized, open- label trial Philippe Bégin Université de Montréal: Universite de Montreal Jeannie Callum University of Toronto Nancy Heddle McMaster University Richard Cook University of Waterloo Michelle P Zeller McMaster University Alan Tinmouth University of Ottawa Dean Fergusson Ottawa Hospital Research Institute Melissa M Cushing Weill Cornell Medicine Marshall J Glesby Weill Cornell Medical College: Weill Cornell Medicine Michaël Chassé Université de Montréal Dana V Devine Canadian Blood Services Nancy Robitaille Héma-Québec Renée Bazin Héma-Québec Nadine Shehata University of Toronto Andrés Finzi Université de Montréal Page 1/34 Allison McGeer University of Toronto Damon Scales University of Toronto Lisa Schwartz McMaster University Alexis F Turgeon Universit Laval Ryan Zarychanski University of Manitoba Nick Daneman University of Toronto Richard Carl n/a Luiz Amorim Hemorio Caroline Gabe McMaster University Martin Ellis Tel Aviv University Erin Jamula McMaster University Julie Carruthers McMaster University Joanne Duncan McMaster University Kayla Lucier McMaster University Chantal Armali Sunnybrook Health Sciences Centre Amie Kron Sunnybrook Health Sciences Centre Dimpy Modi Sunnybrook Health Sciences Centre Marie-Christine Auclair Centre de recherche du CHU Sainte-Justine Meda Avram Centre de recherche du CHU Sainte-Justine Donald M Arnold ( [email protected] ) Page 2/34 McMaster University https://orcid.org/0000-0003-0943-8853 Research Article Keywords: convalescent plasma, SARS-CoV-2, coronavirus, COVID-19 Posted Date: March 5th, 2021 DOI: https://doi.org/10.21203/rs.3.rs-268937/v1 License: This work is licensed under a Creative Commons Attribution 4.0 International License.
    [Show full text]
  • Featured Article Columbia Researchers United Against COVID-19
    Summer/Fall COLUMBIA PATHOLOGY 2020 AND CELL BIOLOGY REPORT Featured Article Columbia Researchers United Against COVID-19 Lab Snapshot Effects of COVID-19 on Histology Lab COVID-19 Response Departmental collection of the clinical response to the pandemic in this issue 3 From the Chair 4 Honors and Awards 9 Faculty Promotions 10 Grants Awarded 13 In Memoriam 15 New Administrative Staff 16 New Faculty 7 17 Research 18 COVID-related Research 20 Feature Article: Columbia Researchers United Build a COVID-19 Patient Biobank 27 Lab Snapshot: Impact of COVID-19 on Histology 28 New Residents & Fellows Columbia Pathology and Cell Biology Report Chairman Kevin A. Roth, MD, PhD Donald W. King, M.D. and Mary Elizabeth King, M.D. Professor of Pathology and Cell Biology Chair, Department of Pathology and Cell Biology Pathologist-in-Chief, CUIMC Department Administrator/CFO Joann Li, PA, MPH Editor and Layout Designer 20 Milan Fredricks Copy Editor and Webmaster Ping Feng Contributing Writers Alvaro Cuesta-Dominguez, Phd Annette Wu, MD Address correspondence to: PCB Reports, Editor c/o Milan Fredricks Columbia University Department of Pathology and Cell Biology 630 W. 168th St., Box 23 New York, NY 10032 E-mail: [email protected] Website: pathology.columbia.edu on the cover: Illustration, men and women wearing masks 24 (Source: graphics4u on envato elements) FROM THE CHAIR A Changing Landscape ARS -CoV-2 had, and world to advance studies of continues to have, a the virus and to develop novel Grants Awarded Sdevastating effect on our SARS-CoV-2 assays and therapies community. At its peak in mid- (https://www.pathology.columbia.
    [Show full text]
  • Development of a Quality Monitoring Program for Platelet Components: a Report of the first Four Years’ Experience At
    ORIGINAL ARTICLE Development of a quality monitoring program for platelet components: a report of the first four years’ experience at Canadian Blood Services_3402 1..9 Elena Levin, Craig Jenkins, Brankica Culibrk, Maria I.C. Gyöngyössy-Issa, Katherine Serrano, and Dana V. Devine ormal biologic differences among donors BACKGROUND: A quality monitoring program (QMP) mean that a degree of variation is inherent in for platelet concentrates (PCs) was implemented at blood components produced for transfusion.1 Canadian Blood Services (CBS) to improve standards Despite this, blood product providers strive to and to better understand platelet (PLT) products by Ngenerate components that are of high quality and are supplementing routine quality control (QC). optimally standardized to guarantee safety and effective- STUDY DESIGN AND METHODS: Annual surveys of ness.2,3 Quality control (QC) of components prepared from PCs from CBS production sites were conducted, with whole blood donations occurs at expiry and focuses on four completed to date (QMP Cycles 1-4) spanning two the product’s safety and compliance with regulatory stan- different PC production methods: PLT-rich plasma dards. For platelet concentrates (PCs), standards include (PRP) and buffy coat (BC). Randomly selected PCs pH, platelet (PLT) count per unit, sterility, and residual were sent to a central laboratory and tested 1 day after white blood cell count if the product is leukoreduced,4,5 all expiry. An expanded panel of tests including CD62P of which are monitored by routine QC at Canadian Blood expression by flow cytometry, mean PLT volume, PLT Services (CBS). Although production of blood compo- count and morphology, extent of shape change, and nents for transfusion purposes has increasingly adopted a PLT metabolic parameters, were applied.
    [Show full text]
  • Collaborative Study on the First WHO Repository of Red Blood Cell
    WHO/BS/2019.2377 ENGLISH ONLY EXPERT COMMITTEE ON BIOLOGICAL STANDARDIZATION Geneva, 21 to 25 October 2019 Collaborative Study on the First WHO Repository of Red Blood Cell Transfusion-Relevant Bacterial Reference Strains Marcel Prax, Kay-Martin Hanschmann and Oleg Krut* and the Collaborative Study Group** *Division of Microbiology, Head Prof Isabelle Bekeredjian-Ding Paul-Ehrlich-Institut,Paul-Ehrlich-Straße 51-59, D-63225 Langen, Germany **ISBT WP Transfusion Transmitted Infectious Diseases Subgroup on Bacteria Chairs: Carl P McDonald and Sandra Ramirez-Arcos See Appendix 1 NOTE: This document has been prepared for the purpose of inviting comments and suggestions on the proposals contained therein, which will then be considered by the Expert Committee on Biological Standardization (ECBS). Comments MUST be received by 27 September 2019 and should be addressed to the World Health Organization, 1211 Geneva 27, Switzerland, attention: Technologies, Standards and Norms (TSN). Comments may also be submitted electronically to the Responsible Officer: Dr Ivana Knezevic at email: [email protected]. © World Health Organization 2019 All rights reserved. This draft is intended for a restricted audience only, i.e. the individuals and organizations having received this draft. The draft may not be reviewed, abstracted, quoted, reproduced, transmitted, distributed, translated or adapted, in part or in whole, in any form or by any means outside these individuals and organizations (including the organizations' concerned staff and member organizations) without the permission of the World Health Organization. The draft should not be displayed on any website. Please send any request for permission to: Dr Ivana Knezevic, Technologies Standards and Norms, Department of Essential Medicines and Health Products, World Health Organization, CH-1211 Geneva 27, Switzerland.
    [Show full text]
  • ACBTSA Weighs What Is Tolerable Risk in the U.S. Blood Supply And
    2018 #31 September 14, 2018 INSIDE: ACBTSA Weighs What Is Tolerable Risk in the U.S. Blood Supply AABB, ABC, ARC Submit and How That May Inform Decision-making a Joint Perspective on Tolerable Risk in Blood The 49th Meeting of the U.S. Department of Health and Human Services (HHS) th Safety at 49 ACBTSA Advisory Committee on Blood and Tissue Safety and Availability (ACBTSA) took Meeting ........................ 3 place in Arlington, Va. on Thursday, September 13th., New Chair Jackie Fredrick, AABB Interorganizational Task Force on Domestic MBA, the former Versiti CEO, lead a one-day meeting to begin an exploration of Disaster and Acts of risk in the blood supply that will eventually result in recommendations to the As- Terrorism Urges sistant Secretary of Health and Human Services (ASH). The meeting focused on Americans to Donate risks from infection from a patient perspective including presentations from patient ahead of Hurricane Florence ....................... 4 advocacy groups and public comments. Its purpose was to inform the committee in Upcoming ABC Webinars advance of formulating specific recommendations to the ASH on how HHS should – Don’t Miss Out! .......... 4 consider a department-wide approach to decision making in this space. 2018 ABC Financial Ratio Survey .......................... 5 Jay Menitove, MD, the past chair of ACBTSA, presented updates from the Sustain- SMT Journal Club ability Workgroup, similar in content to that presented at the ABC Annual Meeting Recording Available ..... 5 in March 2018. He noted that BARDA analyses of the fiscal stability of the blood REGULATORY NEWS .... 6 community, including data from ABC centers, are in progress and should be avail- BRIEFLY NOTED ...........
    [Show full text]
  • 27Th Regional Congress of the ISBT
    27th Regional Congress of the ISBT June 17 - 21, 2017 Copenhagen, Denmark In conjunction with Final Programme The Organisation of Transfusion Centres in Denmark Tab_1 27th Regional Congress of the International Society of Blood Transfusion, Copenhagen, Denmark June 17 - 21, 2017 Tab_2 Tab_3 Tab_4 Tab_5 Acknowledgements Table of Contents Corporate Partners ISBT is pleased to acknowledge the following Corporate Partners Introduction: - Words of Welcome 5 - Future Congresses 7 GOLD - Committees 8 - Reviewers 10 - Congress Organisers 13 ISBT 14 ISBT Working Party & other Meetings 17 General Scientific Information 19 Congress General Information 21 Programme at a Glance 24 Scientific Programme 29 Speaker Index 84 Posters 89 Other Information 93 General Information 94 BRONZE: Social Programme 96 Floor Plans 100 Exhibition 2 3 Introduction Introduction Word of Welcome Congress President and Chairman of the Local Organizing Committee Dear Friends and Colleagues, We – the local organizing and scientific committees – are looking forward to seeing you at the 27th Regional Congress of the International Society of Blood Transfusion in Copenhagen, Denmark, June 17-21, 2017. With the help from multiple international reviewers and through a scientific meeting with the participation of recognized international experts the final educational and scientific programme with invited speakers, oral and poster presentations has been put together. We are happy that it seems to fulfill our aims for the congress so it will confront you with the frontiers of research and knowledge in transfusion medicine and related fields. We also hope to see you at Saturday’s local sessions to get the Scandinavian angle of our field. However, the success of the congress depends on you! We hope you will challenge the invited speakers and presenters with intriguing questions and comments to secure lively discussions.
    [Show full text]
  • Proceedings of the Food and Drug Administration Public Workshop on Pathogen Reduction Technologies for Blood Safety 2018
    CONFERENCE REPORT Proceedings of the Food and Drug Administration public workshop on pathogen reduction technologies for blood safety 2018 Chintamani Atreya ,1 Simone Glynn,2 Michael Busch,3 Steve Kleinman,4 Edward Snyder,4 Sara Rutter,5 James AuBuchon,6 Willy Flegel,7 David Reeve,8 Dana Devine,9 Claudia Cohn ,9 Brian Custer,3 Raymond Goodrich,10 Richard J. Benjamin,11 Anna Razatos,12 Jose Cancelas,13 Stephen Wagner,8 Michelle Maclean,14 Monique Gelderman,15 Andrew Cap,16 and Paul Ness17 n November 29, 2018, experts in the field of mitigate these risks in the United States including the introduc- infectious diseases, pathogen reduction technol- tion of increasingly sensitive laboratory screening testing ogies (PRTs) and other participants from blood platforms and PRTs for PLTs and plasma products. In a first centers, academia, and industry gathered at the part, the session includes a general overview of the evolution OFood and Drug Administration (FDA) White Oak Campus in of responses to established, emerging, and reemerging Silver Spring, Maryland, for a 2-day public workshop entitled transfusion-transmitted infectious diseases in the past 50 years. “ ” Pathogen Reduction Technologies for Blood Safety. The Further, it addresses the need for ongoing surveillance for and workshop opened with welcome remarks from Dr. Nicole systematic responses to emerging infectious diseases (EIDs), fi Verdun, Director, Of ce of Blood Research and Review optimally with sensitive metagenomics, multiplexed nucleic (OBRR), Center for Biologics Evaluation and Research acid amplification technology (NAT) and serologic testing (CBER), FDA, followed by introductory remarks from strategies in sentinel global donor populations. This is followed Dr.
    [Show full text]
  • The Centre for Blood Research Presents…
    The Centre for Blood Research presents… Live Webcast: https://tinyurl.com/2017NBS-Webcast For registration information visit www.cbr.ubc.ca Each registered participant will be able to claim 6.5 MOC Section 1 credits by attending all sessions. 7:15 – 7:50 Registration and Breakfast 7:50 – 8:00 Dana Devine, PhD, UBC, Opening Remarks 8:00 – 8:35 Peter Newman, PhD, BloodCenter of Wisconsin, “CRISPR-mediated generation of antigeni- cally-distinct platelet progenitors from human iPS cells” 8:35 – 9:10 Heather Pidcoke, MD, PhD, Terumo BCT, “Refrigerated (4°C) Platelets: New Opportunities for Improving the Care of Bleeding Patients” 9:10 – 9:45 Shibani Pati, MD, PhD, Blood Systems Research Institute, “Regulation of Organ Injury in Trau- ma and Critical Care Medicine by Plasma and Platelet Transfusion” 9:45 – 10:25 Coffee break and posters 10:25 – 10:45 Selected Abstract Presentations - Andrew Wei-Yeh Shih, Emel Islamzada 10:45 – 10:55 Hugh Kim, DMD, PhD, FRCD(C), UBC, “Platelet signaling from an oral health perspective” 10:55 – 11:30 Mohandas Narla, DSc, New York Blood Centre, “Insights into Erythropoiesis and Red Cell Biol- ogy relevant to Transfusion Medicine” 11:30 – 12:05 James Piret, ScD, FCIC, UBC, “Raman Spectroscopy as a Process Analytical Technology for Cellular Therapy Applications” 12:05 – 12:35 “Shot-gun" talks 12:35 - 1:35 Buffet lunch and posters 1:35 – 2:10 Jean Wang, MD, PhD, FRCPC, Princess Margaret Cancer Centre, “A Social History of Transfu- sion Medicine” 2:10 – 2:25 Krista Klokeid, “Transfusion medicine through the eyes of
    [Show full text]
  • Pathogen Reduction Technologies for Blood Safety; Public Workshop Part 2
    UNITED STATES FOOD AND DRUG ADMINISTRATION PATHOGEN REDUCTION TECHNOLOGIES (PRT) FOR BLOOD SAFETY PUBLIC WORKSHOP Silver Spring, Maryland Thursday, November 29, 2018 2 1 PARTICIPANTS: 2 Welcome: 3 NICOLE VERDUN, M.D.. OBRR, CBER 4 Food and Drug Administration 5 Opening Remarks: 6 PETERS MARKS, M.D., Ph.D. CBER 7 Food and Drug Administration 8 SESSION 1: Blood-Borne Infectious Agents and Their Impact on Blood Safety: 9 SIMONE GLYNN, M.D., MPH, Moderator 10 NHLBI National Institutes of Health 11 Risks to Blood Safety From Infectious Agents: 12 MICHAEL BUSCH, M.D., Ph.D. 13 Vitalant Research Institute 14 Pathogen Reduction: An Overview of Policy Issues: 15 STEVE KLEINMAN, M.D. University of British Columbia 16 Pathogen Reduction Technologies for Platelets: 17 Current Status in the United States: 18 EDWARD SNYDER, M.D., FACP Yale University, Yale New Haven Hospital 19 PRT for Plasma in the United States: 20 JAMES AUBUCHON, M.D., FACAP, FRCP (Edin) 21 Bloodworks Northwest, University of Washington 22 3 1 PARTICIPANTS (CONT'D): 2 Panel Discussion: 3 MICHAEL BUSCH, M.D., Ph.D. Vitalant Research Institute 4 STEVE KLEINMAN, M.D. 5 University of British Columbia 6 EDWARD SNYDER, M.D., FACP Yale University, Yale New Haven Hospital 7 JAMES AUBUCHON, M.D., FACAP, FRCP (Edin) 8 Bloodworks Northwest, University of Washington 9 SESSION 2: Implementation of Pathogen Reduction Technology for Blood Products in the U.S.: 10 BILL FLEGEL, M.D., Moderator 11 NIH Clinical Center 12 Experience Implementing PRT: 13 DAVID REEVE, MBA, MHA American Red Cross 14 PRT Implementation in a Hospital-Based Blood 15 Center & Acceptance by Hospital Staff: 16 BILL FLEGEL, M.D., Moderator NIH Clinical Center 17 Impact of PRT on Platelet Quality, Count, and 18 Clinical Implications: 19 DANA DEVINE, Ph.D.
    [Show full text]
  • The Effect of Timing of Gammairradiation on Hemolysis And
    Vox Sanguinis (2013) © 2013 International Society of Blood Transfusion SHORT REPORT DOI: 10.1111/vox.12112 The effect of timing of gamma-irradiation on hemolysis and potassium release in leukoreduced red cell concentrates stored in SAGM K. Serrano,1,2,3 D. Chen,2,3 A. L. Hansen,4 E. Levin,1,2,3 T. R. Turner,4 J. D. R. Kurach,4 J. P. Acker4 & D. V. Devine1,2,3 1Canadian Blood Services, Centre for Innovation, Vancouver, BC, Canada 2Centre for Blood Research, University of British Columbia, Vancouver, BC, Canada 3Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada 4Canadian Blood Services, Centre for Innovation, Edmonton, AB, Canada While irradiation of red cell concentrates (RCC) prevents graft-versus-host disease in susceptible transfusion recipients, it also damages red blood cells (RBC). To understand the ability of irradiation regulations to prevent transfusion of inferior units, we irradiated 980 RCC in saline-adenine-glucose-mannitol (SAGM) using various combinations of pre-irradiation age and post-irradiation storage times, and measured hemolysis and extracellular potassium levels. We observed unac- ceptably high hemolysis (>0Á8%) in some RCC and elevated extracellular potas- sium levels in all gamma-irradiated RCC. This suggests that more restrictive Received: 19 August 2013, revised 8 October 2013, storage times should be considered for RCC in SAGM. accepted 10 October 2013 Key words: blood components, component production, quality control. Introduction possible, but no later than 14 days after irradiation and, in any case, no later than 28 days after collection.’ The Gamma-irradiation of red cell concentrates (RCC) reduces British Committee for Standards in Haematology (BCSH) the risk of graft-versus-host disease in immunocompro- has even more restrictive standards, stating ‘Red cells may mised transfusion recipients [1].
    [Show full text]