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Lexapro® (LEX-A-Pro) Escitalopram Oxalate (ES-Sigh-Talo-Pram OX-A-Late) Consumer Medicine Information (CMI)

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Lexapro® (LEX-A-Pro) Escitalopram Oxalate (ES-Sigh-Talo-Pram OX-A-Late) Consumer Medicine Information (CMI) Lexapro® (LEX-a-pro) Escitalopram oxalate (ES-sigh-talo-pram OX-a-late) Consumer Medicine Information (CMI) What is in this leaflet sleep, often waking up early, loss of sex drive, lack of energy and feeling guilty over nothing. This leaflet contains answers to some Before you take it common questions about Lexapro. Lexapro corrects this chemical It does not contain all the information imbalance and may help relieve the symptoms of depression. When you must not take that is known about Lexapro. It does it not take the place of talking to your Lexapro may also be used to treat doctor or pharmacist. patients who may avoid and/or are Do not take Lexapro if you are All medicines have risks and fearful of social situations. allergic to it, to any medicine benefits. Your doctor has weighed Lexapro may also be used to treat containing escitalopram, or any of the risk of you using this medicine patients who have excessive anxiety the ingredients listed at the end of against the benefits he/she expects it and worry. this leaflet. will have for you. Lexapro may also be used to treat Symptoms of an allergic reaction If you have any concerns about irrational fears or obsessional may include shortness of breath, using this medicine, ask your behaviour (obsessive-compulsive wheezing or difficulty breathing, doctor or pharmacist. disorder). Obsessive-compulsive swelling of the face, lips, tongue or other parts of the body, or rash, Keep this leaflet with the medicine. disorder involves having both obsessions and compulsions. itching or hives on the skin. You may need to read it again. Obsessions are unwanted thoughts Do not take Lexapro at the same that occur over and over again. time as the following other Compulsions are the ongoing need to medicines: repeat certain actions as a result of • pimozide, a medicine used to What Lexapro is used these thoughts. for treat mental disorders Your doctor, however, may prescribe • monoamine oxidase inhibitors it for another purpose. Lexapro is used to treat depression. (MAOIs), such as phenelzine, Ask your doctor if you have any tranylcypromine and It belongs to a group of medicines questions about why it has been moclobemide which are also used called selective serotonin reuptake prescribed for you. for the treatment of depression. inhibitors (SSRIs). They are thought to work by their actions on brain This medicine is only available with One day must elapse after you chemicals called amines which are a doctor's prescription. have finished taking involved in controlling mood. Lexapro is not addictive. However, if moclobemide before you start taking Lexapro. If you have taken Depression is longer lasting or more you suddenly stop taking it, you may any other MAOI you will need to severe than the "low moods" get side effects. wait 14 days. After stopping everyone has from time to time due Tell your doctor if you get any side Lexapro, you must allow 14 days to the stress of everyday life. It is effects after stopping Lexapro. before taking any MAOI thought to be caused by a chemical including moclobemide. imbalance in parts of the brain. This imbalance affects your whole body Taking Lexapro with MAOIs and can cause emotional and physical may cause a serious reaction with symptoms such as feeling low in a sudden increase in body spirit, loss of interest in activities, temperature, extremely high being unable to enjoy life, poor blood pressure and severe appetite or overeating, disturbed convulsions. Your doctor will LEXAPRO 1 know when it is safe to start 3. you are breast-feeding or The effects of Lexapro in elderly Lexapro after the MAOI has been planning to breast-feed. patients are similar to that in other stopped. Do not take Lexapro if you are patients. Do not take it after the expiry date breast-feeding unless you and If you have not told your doctor printed on the pack. your doctor have discussed the about any of the above, tell them If you take it after the expiry date has risks and benefits involved. It is before you use Lexapro. passed, it may not work as well. The not recommended that you breast- expiry date refers to the last day of feed while taking Lexapro as it is Taking other medicines excreted in breast milk. the month. Tell your doctor if you are taking Do not take it if the packaging is 4. you have, or have had, the any other medicines, including any torn or shows signs of tampering. following medical conditions: that you buy without a • a tendency to bleed or bruise prescription from your pharmacy, Before you start to take easily supermarket or health food shop. it • diabetes Some medicines and Lexapro may interfere with each other. These Tell your doctor if: • heart disease, especially long QT include: 1. you have allergies to any other syndrome or other conduction • bupropion, a medicine helping to substances such as foods, disorders treat nicotine dependence preservatives or dyes. • conditions causing changes in the • medicines used to treat reflux and 2. you are pregnant or intend to levels of sodium, potassium or ulcers, such as cimetidine, become pregnant. magnesium in the blood (electrolytes) omeprazole, esomeprazole and Medicines like Lexapro have been lansoprazole shown to reduce the quality of sperm • kidney disease • medicines known to prolong in animal studies. Theoretically, this • liver disease could affect fertility but impact on bleeding, e.g. aspirin or other • bipolar disorder (manic non-steroidal anti-inflammatory human fertility has not been observed depression) drugs (NSAIDs) as yet with Lexapro. • a history of seizures or fits • ticlopidine and warfarin, Do not take Lexapro if you are medicines used to prevent blood pregnant unless you and your doctor • restlessness and/or a need to have discussed the risks and benefits move often clots involved. • eye problems, such as certain • mefloquine, an anti-malaria Make sure your doctor and/or kinds of glaucoma (increased medicine midwife know you are on Lexapro. pressure in the eye). • sumatriptan, used to treat When taken during pregnancy, migraines particularly in the last three months 5. you are receiving • tramadol, used to relieve pain of pregnancy, medicines like electroconvulsive therapy. • medicines affecting the chemicals Lexapro may affect the general in the brain condition of your newborn baby and If you have any of the above medical • medicines that reduce the level of may increase the risk of a serious conditions, your doctor may perform sodium, potassium or magnesium condition in babies, called persistent additional tests, such as an ECG to in the blood, e.g. diuretics ('fluid pulmonary hypertension of the check your heart and blood tests to tablets') newborn (PPHN), making the baby check sodium, potassium and/or magnesium levels. breathe faster and appear bluish. • some heart medications, e.g. These symptoms usually begin flecainide, propafenone, Do not give Lexapro to a child or during the first 24 hours after the metoprolol adolescent. baby is born. If this happens to your • Antiarrhythmic medicines, used There is no experience with its use in baby, you should contact your doctor to treat irregular heartbeats, e.g. children or adolescents under 18 and/or midwife immediately. amiodarone, disopyramide, years old. If used during pregnancy Lexapro sotalol Lexapro can be given to elderly should never be stopped abruptly. • Antifungal medicines e.g. patients over 65 years of age with a Ask your doctor or pharmacist for fluconazole, voriconazole reduced dose. advice before taking any medicine. • Some antibiotics, e.g. azithromycin, clarithromycin, LEXAPRO 2 erythromycin, roxithromycin, It is recommended that patients with The underlying illness may persist amphotericin, gentamicin liver disease receive an initial dose of for a long time and if you stop your • Antihistamine medicines, used to 5 mg daily for the first two weeks. treatment too soon, your symptoms relieve the symptoms of allergy Your doctor may increase the dose to may return. (such as hay fever) or colds and 10 mg daily. Do not stop taking this medicine 'flu, e.g. terfenadine, loratadine, Your doctor may have prescribed a suddenly. diphenhydramine different dose. If Lexapro is stopped suddenly you • tryptophan, an amino-acid Ask your doctor or pharmacist if may experience mild, but usually • lithium used to treat mood swings you are unsure of the correct dose temporary, symptoms such as and some types of depression for you. dizziness, pins and needles, electric shock sensations, sleep disturbances • antipsychotics, a class of They will tell you exactly how much (vivid dreams, inability to sleep), medicines used to treat certain to take. feeling anxious or agitated, mental and emotional conditions, Follow the instructions they give headaches, feeling sick (nausea), e.g. risperidone, thioridazine and you. vomiting, sweating, tremor (shaking), haloperidol If you take the wrong dose, Lexapro feeling confused, feeling emotional • tricyclic antidepressants, e.g. may not work as well, and your or irritable, diarrhoea, visual imipramine, desipramine condition may not improve. disturbances, or fast or irregular • St John's Wort (Hypericum heartbeats. perforatum), a herbal remedy How to take it When you have completed your • any other medicines used to treat Swallow the tablets whole with a course of treatment, the dose of seizures, depression, anxiety, full glass of water. Lexapro is gradually reduced over a couple of weeks rather than stopped obsessive-compulsive disorder or Do not chew them. pre-menstrual dysphoric disorder abruptly. These medicines may be affected by When to take it Your doctor will tell you how to reduce the dosage so that you do not Lexapro or may affect how well it Take Lexapro as a single dose get these unwanted effects. works. You may need to use different either in the morning or in the amounts of your medicines or take evening.
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