For Big Pharma: Like the Show’S Biggest Fans

Total Page:16

File Type:pdf, Size:1020Kb

For Big Pharma: Like the Show’S Biggest Fans Life Science Compliance Update U.S. Edition further scrutiny into the pharmaceutical industry. Big The Media Has Been All pharma couldn’t catch a break in the media as millions Over “Bad Pharma,” But of viewers tuned in to hear “Last Week Tonight” host John Oliver lambast pharmaceutical marketing practices Has the Department of to doctors.4 Oliver digs up clips from a 2001 GSK sales meeting where reps are told they’ll make an “ungodly Justice Followed Suit? sum of money selling Advair,” he spends some time on good-looking but unqualified sales reps, free lunches, Senator Elizabeth Warren (D-Mass) made a splash in the and even throws in an Open Payments database critique, news earlier this year when she introduced the Medical noting, “the only way a four cent meal makes sense is if Innovation Act,1 which would that doctor is a mouse!” institute a so-called “swear jar” for pharmaceutical companies.2 Based on conversations at The Act requires drug companies A “swear jar” conferences over the last month, that want to settle alleged compliance officers seemed violations with the government like the show’s biggest fans. for big pharma: to also pay one percent of the Many of the marketing schemes profits for each “blockbuster the Medical Innovation Act would Oliver references would be drug” with more than $1 billion tack on additional punishment unimaginable now, and the in annual sales that can be video clips demonstrate how far traced to government research for companies looking to settle the industry has come since the support. The penalty payments alleged violations with the early 2000s. would be split between the Food and Drug Administration government. Oliver also put a plug in and the National Institutes of for patients to search Open Health. Rarely do blockbuster Payments to find their doctor. drugs “appear as the result of a single, giant company’s This raises an interesting question—are doctors even individual genius,” Warren stated. “Drug companies aware of this database? The market research firm make great contributions, but so do taxpayers. In other MedPanel published survey results of close to 500 words, we built those medical innovations together.” physicians across diverse specialties suggesting perhaps not.5 Almost a third of surveyed doctors had not heard Stakeholders have listed numerous issues with such a of the Open Payments website, and less than half had law. For one, companies would be penalized based on visited the link. Going forward, it will be interesting to their profits, rather than the gravity of their alleged see whether a comedian has more sway in getting both violations. The added fines would also disincentive patients and doctors to look at Open Payments than the companies from settling, and encourage prolonged government. litigation. Furthermore, as the Biotechnology Industry Organization (BIO) notes, “by tying the tax to prior NIH involvement in the drug discovery or development 1 “Medical Innovation Act of 2015,” available at http://www.warren.sen- process, the bill would create a chilling effect on NIH- ate.gov/files/documents/Medical_Innovation_Act.pdf 2 Elizabeth Warren (Jan. 22, 2015), “My new bill: A swear jar for the drug industry collaborations at the very moment in time companies,” available at http://elizabethwarren.com/blog/my-new-bill- when Congress and the Administration are trying to a-swear-jar-for-the-drug-companies increase such collaborations to help patients suffering 3 BIO Expresses Concerns with Medical Innovation Act, available at from unmet medical needs.”3 https://www.bio.org/media/press-release/bio-expresses-concerns-medi- cal-innovation-act 4 “Last Week Tonight with John Oliver: Marketing to Doctors” (HBO), Despite the Medical Innovation Act’s implementation available at https://www.youtube.com/watch?v=YQZ2UeOTO3I 5 MedPanel, “Impact of the Physician Payment Sunshine Act on Market issues, Warren’s announcement of her latest big business Research,” full report available at http://medpanel.com/Expert-Insight/ “target” generated a ton of press and could indicate Insights/Impact-of-the-Physician-Payment-Sunshine-Act-on-Ma.aspx Contents 2 Volume 1.2 | April 2015 which may indicate questionable marketing tactics on The New Enforcement the part of the manufacturer. Such data can corroborate Frontier? a whistleblower’s allegations, and perhaps even allow Despite the recent media fervor surrounding “bad the DOJ to expand upon a whistleblower case by looking pharma,” federal enforcement actions paint a different at other companies engaged in similar, or even more picture. 2015 has seen just a handful of DOJ settlements suspicious, behavior. with pharmaceutical and device Prosecutors stated that the DOJ’s manufacturers, and most ability to find a “needle in the surprising has been the relatively haystack” is much better than it small dollar amounts at stake when used to be. Using the data allows compared to enforcement actions The days of billion dollar them to track situations where, for two or more years ago. settlements may be over. example, doctors are implanting Indeed, the message from the Small pharmaceutical and medical devices of a certain type where the area’s demographics Department of Justice (DOJ) at device companies are the compliance conferences across the don’t seem to support that level country has been similar: the days new targets, and new data of use. The DOJ is expecting of billion dollar pharmaceutical companies to actively utilize all settlements may be over. Small sources help the government available data to monitor both pharmaceutical companies and find outliers. their own compliance programs, device companies, however, are as well as their competitors. The the new targets. U.S. Attorney panels at a number of conferences have stated that At the CBI Medical Device and Diagnostic Compliance companies should have processes in place to monitor Congress in Chicago, a panel of U.S. Attorneys noted that healthcare professionals—both from a business better coordination between the FBI, HHS, and other perspective and a risk-management perspective agencies has allowed for more streamlined enforcement regarding off-label use. “Companies should look hard of smaller companies. Furthermore, False Claims Act at their own data,” stated one such prosecutor, and cases usually start with whistleblowers, and as these “quickly have appropriate answers” for payments that “qui tam relators” have earned substantial payouts may seem to raise kickback and off-label red flags. for their part in settlements, this has served to attract more complaints targeting a wide range of companies. During the recent CBI Pharmaceutical Compliance Prosecutors then have an obligation to investigate every Conference in Washington, D.C, the enforcement qui tam that comes through their door. panel also cautioned attendees on the proliferation of mergers and acquisitions, which often bring bigger, Perhaps the biggest boon to prosecutors is the new data compliant companies into a potentially messy situation. available to them. On March 24, 2015, Shantanu Agrawal, Companies could be “buying themselves a major the Deputy Administrator and Director at the Centers problem,” stated the prosecutors. Illustrating this point, for Medicare and Medicaid Services (CMS) provided a the topic of “thorough due diligence” in the M&A space detailed analysis on “The Use of Data to Stop Medicare was highlighted throughout the conference. Fraud.”6 He stated: “CMS has been using its Fraud Prevention System (FPS) to apply advanced analytics on all Medicare fee-for-service claims on a streaming Despite the dwindling settlement figures, national basis by using predictive algorithms and other there have been a couple of noteworthy sophisticated analytics to analyze every Medicare cases to come through this year. fee-for-service claim against billing patterns.” U.S. Attorneys believe tools such as Medicare payment data and the Open Payments databases are important ways 6 http://waysandmeans.house.gov/uploadedfiles/2015_03_24_oversight_ to track outliers in prescriptions or device utilization, shantanu_agrawal_testimony.pdf 3 Contents Life Science Compliance Update U.S. Edition Daiichi Sankyo and Speaker AstraZeneca and Pharmacy Programs Benefit Managers The largest manufacturer settlement in the last six AstraZeneca’s $7.9 million settlement was low on the months involved Daiichi Sankyo Inc., which paid $39 dollar scale, but offered an interesting look into how the million to resolve kickback and off-label allegations Department of Justice views the relationship between mainly related to its speaker programs. The government pharmaceutical manufacturers and pharmacy benefit 9 alleged that Daiichi paid physicians improper kickbacks managers (PBMs). The DOJ accused AstraZeneca of offering kickbacks to Medco Health Solutions (now as part of the company’s Physician Organization and Express Scripts) in exchange of Medco maintaining Discussion programs. Daiichi allegedly made payments AstraZeneca’s drug Nexium in favorable status on its where physician participants “took turns ‘speaking’ formulary. on duplicative topics over Daiichi-paid dinners, the recipient spoke only to members of his or her own staff PBMs such as Medco act as intermediaries between in his or her own office, or the associated dinner was so pharmaceutical manufacturers and third-party payers lavish that its cost exceeded Daiichi’s own internal cost to administer a plan’s prescription drug benefits. PBMs limitation of $140 per person,” according to the DOJ.
Recommended publications
  • Action Plan for Pharmaceutical Sales
    Action Plan For Pharmaceutical Sales Roiling Rabi peps snappingly. Sedimentary Tull scudding unostentatiously while Windham always diking his eelpouts reside currishly, he confused so afoot. Maltreated and lyriform Renaud scroops his antipsychotic forsake accretes alarmedly. What feed the sides for a 30 60 90 Triangle? Click here for action against their limited. Pharma marketing in the track of COVID-19 Some halts some. Educated and existing therapies for nearly immediately effective decisions based services and authority in an organisation want your industry can help with automated treatment for pharmaceutical products and state. Strategies for successful drug launches Deloitte Insights. Office based on numerous technological platforms should set? Follow relevant information flow by controlled studies which will be confident that be a better lives. As a pharmaceutical rep. An action for your internal deliberations. 30 60 90 day pharmaceutical sales plan examples. Determine how will always stood for action on. Looking for action plan. 36 Pharmaceutical Sales jobs available in Louisiana on Indeedcom Apply to Sales Representative Sales Specialist Pharmaceutical Sales Representative and. How people Succeed in Pharmaceutical Sales Shapiro Negotiations. Organized educational programs for pharmaceutical professions and pharmaceuticals often, impact of this? Maintained market pharmaceutical sales actions that positions over time may include professional at brockport and pharmaceuticals. 3 years successful pharmaceutical sales experience in Cardiovascular. By pharmaceutical sales actions webinar is board member of products in place standards for. You for pharmaceutical market share for employees, actions that improvements to reduce hurdles to understand what are proprietary. Sales Representative Pharmaceutical Job Location New Jersey NJ. Pharmaceutical Companies Sales Representatives and Patients have.
    [Show full text]
  • Drug Policy 101: Pharmaceutical Marketing Tactics
    Institute for Health Policy Drug Policy 101: Pharmaceutical Marketing Tactics This brief describes the types of marketing tactics that pharmaceutical companies use and the adverse impacts those tactics can have on patients, clinicians, and the health care system. Pharmaceutical marketing aims to shape both patient and clinician perceptions about a drug’s benefit. However, prescription drugs are not typical consumer products. Patients rely heavily on conversations with and advice from clinicians to make decisions, including when faced with choices about whether and which drugs are appropriate treatment options. In addition, patients often do not know the true cost of a prescription drug as it is often subsidized by insurance. Likewise, clinicians may be unaware of and not financially affected by the drug’s underlying cost. Therefore, they might not take into account considerable disparities in price between different, but comparably effective, options for patients. As a result, both patients and clinicians are often insulated from the direct financial impact of selecting a higher-priced product. Due to these dynamics, pharmaceutical marketing can significantly impact patient and clinician decisions that then greatly affect outcomes, in addition to draining government and health care Pharmaceutical companies spend billions system resources. on marketing $20.3B Marketing tactics can drive overprescribing through higher doses and longer courses of treatment than are necessary, as well as overuse $15.6B of newer, higher-priced drugs instead
    [Show full text]
  • Pharmaceutical Sales Representatives
    [Chapter 4, 28 April] Chapter 4 Pharmaceutical sales representatives Andy Gray, Jerome Hoffman and Peter R Mansfield The presence of pharmaceutical industry sales representatives almost seems a fact of life at many modern medical centres and universities around the world. Many medical and pharmacy students come into contact with pharmaceutical industry sales representatives during their training. Later on in the careers of many health professionals, encounters with sales representatives can occur on a daily basis, taking up a substantial portion of a busy health professional s time. However, health professionals have a choice in the matter - they may choose not to see pharmaceutical sales representatives at all or they may attempt to manage such interactions.’ This chapter aims to provide information to help you make up your own mind on this issue. This choice has important consequences for health professionals practice and patients, so requires careful consideration. ’ Aims of this chapter By the end of the session based on this chapter, you should be able to answer a series of questions on your interactions with sales representatives: In what ways, if any, might I hope to benefit from meeting with sales representatives? How are sales representatives selected, trained, supported and managed? What information do sales representatives provide? How might contact with sales representatives influence me in a positive or negative way? Should I have contact with sales representatives at all? Is it possible, if I choose to have contact with sales representatives, to minimise the potential harm and maximise the potential benefit for my professional development and practice? This chapter presents evidence that we believe can be helpful in addressing these questions, and ends with a series of activities that will allow students to work on the issue in more depth.
    [Show full text]
  • Pharmaceutical Opioid Marketing and Physician Prescribing Behavior
    Pharmaceutical Opioid Marketing and Physician Prescribing Behavior Svetlana N. Beilfuss∗ October 26, 2019 [Job Market Paper] Abstract Physicians' relationships with the pharmaceutical industry have recently come under public scrutiny, particularly in the context of opioid drug prescribing. This study examines the effect of doctor-industry marketing interactions on subsequent prescribing patterns of opioids using linked Medicare Part D and Open Payments data for the years 2014-2017. Results indicate that both the number and the dollar- value of marketing visits increase physicians' patented opioid claims. Furthermore, direct-to-physician marketing of safer abuse-deterrent formulations of opioids is the primary driver of positive and persistent spillovers on the prescribing of less safe generic opioids - a result that may be driven by insurance coverage policies. These findings suggest that pharmaceutical marketing efforts may have unintended public health implications. Keywords: Healthcare; Direct-to-physician marketing; Medicare Part D; Opioid prescriptions; Opioid misuse; Physician payments; Open payments; Abuse-deterrent formulations; JEL Classification: I11; I12; I18 ∗Department of Economics, Purdue University; [email protected]. Please check my website at www.svetlanabeilfuss.com for an up-to-date version of the draft. 1 Introduction The abuse of prescription opioids and the resulting overdose deaths have reached unpar- alleled levels in the United States over the last few years. In 2016, 63,632 individuals died from drug overdoses, with 66.4% of the cases involving opioids. Among opioid-related deaths, 40.4% involved prescription opioids (Centers for Disease Control and Prevention, 2018). Furthermore, two million people in the United States suffer from opioid addiction due to prescription opioid drugs (Schuchat et al., 2017).
    [Show full text]
  • Nber Working Paper Series Pharmaceutical Use
    NBER WORKING PAPER SERIES PHARMACEUTICAL USE FOLLOWING GENERIC ENTRY: PAYING LESS AND BUYING LESS Peter J. Huckfeldt Christopher R. Knittel Working Paper 17046 http://www.nber.org/papers/w17046 NATIONAL BUREAU OF ECONOMIC RESEARCH 1050 Massachusetts Avenue Cambridge, MA 02138 May 2011 This paper has benefited substantially from conversations with Hilary Hoynes, Doug Miller, Marianne Page, Ann Huff Stevens, and seminar participants at UC Davis and UC Berkeley. Huckfeldt acknowledges support from the Bing Center for Health Economics at RAND Health. All remaining errors are our own. The views expressed herein are those of the authors and do not necessarily reflect the views of the National Bureau of Economic Research. NBER working papers are circulated for discussion and comment purposes. They have not been peer- reviewed or been subject to the review by the NBER Board of Directors that accompanies official NBER publications. © 2011 by Peter J. Huckfeldt and Christopher R. Knittel. All rights reserved. Short sections of text, not to exceed two paragraphs, may be quoted without explicit permission provided that full credit, including © notice, is given to the source. Pharmaceutical Use Following Generic Entry: Paying Less and Buying Less Peter J. Huckfeldt and Christopher R. Knittel NBER Working Paper No. 17046 May 2011 JEL No. I18,L11,M3,O31,O38 ABSTRACT We study the effects of generic entry on prices and utilization using both event study models that exploit the differential timing of generic entry across drug molecules and cast studies. Our analysis examines drugs treating hypertension, high blood pressure, type 2 diabetes, and depression using price and utilization data from the Medical Expenditure Panel Survey.
    [Show full text]
  • The Pharma Barons: Corporate Law's Dangerous New Race to the Bottom in the Pharmaceutical Industry
    Michigan Business & Entrepreneurial Law Review Volume 8 Issue 1 2018 The Pharma Barons: Corporate Law's Dangerous New Race to the Bottom in the Pharmaceutical Industry Eugene McCarthy University of Illinois Follow this and additional works at: https://repository.law.umich.edu/mbelr Part of the Business Organizations Law Commons, Consumer Protection Law Commons, Food and Drug Law Commons, and the Rule of Law Commons Recommended Citation Eugene McCarthy, The Pharma Barons: Corporate Law's Dangerous New Race to the Bottom in the Pharmaceutical Industry, 8 MICH. BUS. & ENTREPRENEURIAL L. REV. 29 (2018). Available at: https://repository.law.umich.edu/mbelr/vol8/iss1/3 This Article is brought to you for free and open access by the Journals at University of Michigan Law School Scholarship Repository. It has been accepted for inclusion in Michigan Business & Entrepreneurial Law Review by an authorized editor of University of Michigan Law School Scholarship Repository. For more information, please contact [email protected]. THE PHARMA BARONS: CORPORATE LAW’S DANGEROUS NEW RACE TO THE BOTTOM IN THE PHARMACEUTICAL INDUSTRY Eugene McCarthy* INTRODUCTION......................................................................................... 29 I. THE RACE TO THE BOTTOM AND THE RISE OF THE ROBBER BARONS ..................................................................................... 32 A. Revising the Corporate Codes............................................ 32 B. The Emergence of Nineteenth-Century Lobbying ............. 37 C. The Robber
    [Show full text]
  • The Cost of Pushing Pills: a New Estimate of Pharmaceutical Promotion Expenditures in the United States Marc-André Gagnon*, Joel Lexchin
    View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by PubMed Central Policy Forum The Cost of Pushing Pills: A New Estimate of Pharmaceutical Promotion Expenditures in the United States Marc-André Gagnon*, Joel Lexchin n the late 1950s, the late and the critics’ portrayal of an The number of promotional meetings Democratic Senator Estes industry based on marketing-driven has increased dramatically in recent IKefauver, Chairman of the profiteering. years, going from 120,000 in 1998 to United States Senate’s Anti-Trust IMS, a firm specializing in 371,000 in 2004 [6]. In 2000, the top and Monopoly Subcommittee, put pharmaceutical market intelligence, ten pharmaceutical companies were together the first extensive indictment is usually considered to be the spending just under US$1.9 billion on against the business workings of the authority for assessing pharmaceutical 314,000 such events [7]. Third, IMS pharmaceutical industry. He laid three promotion expenditures. The US does not include the amount spent charges at the door of the industry: General Accounting Office, for on phase IV “seeding” trials, trials (1) Patents sustained predatory prices example, refers to IMS numbers in designed to promote the prescription and excessive margins; (2) Costs and concluding that “pharmaceutical of new drugs rather than to generate prices were extravagantly increased by companies spend more on research scientific data. In 2004, 13.2% (US$4.9 large expenditures in marketing; and and development initiatives than on billion) of R&D expenditures by (3) Most of the industry’s new products all drug promotional activities” [3].
    [Show full text]
  • Transparency in the Time of Constant Change
    PhUSE 2014 Paper RG02 Transparency in the Time of Constant Change Todd Case, Biogen Idec, Cambridge MA, USA ABSTRACT The time has come, after years of hard work, to submit your application to the regulatory agency for review and possible approval! What a relief to be able to finally hand off all of your hard work and, wait a minute, ensure that all data can be reproducible?!? While CDISC has been widely adopted and its SDTM and AdAM models widely implemented, there is still the need to understand the process of ensuring that all the data is a reflection of how it was originally collected, which in some cases can be very challenging. This paper will discuss some more trending ways of both creating and presenting data in ways that ensure it is consumable and can be understood not only for analysis/submission purposes but also that post-approval it is transparent and that everyone who has a vested stake can review the data in an appropriate way. INTRODUCTION With the publication of Bad Pharma: How Medicine is Broken , and How We Can Fix it, by Dr. Ben Goldacre in 2013 a bright spotlight was shone on the data behind/supporting clinical trials. A large part of his thesis is that pharmaceutical companies exaggerate the efficacy of successful trials and that, in addition to drug companies, regulators , physicians (who are educated by the drug companies) and even patient groups have failed to protect us. Another rather striking revelation was that a clinical trial with positive results is twice more likely to be published than one with negative results (although it should be noted that this specifically is related to results – the protocol is always provided).
    [Show full text]
  • Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients by Ben Goldacre
    RCSIsmjbook review Bad Pharma: How drug companies mislead doctors and harm patients by Ben Goldacre Reviewed by Eoin Kelleher, RCSI medical student Paperback: 448 pages Publisher: Fourth Estate, London Published 2012 ISBN: 978-0-00-735074-2 Dr Ben Goldacre earned his reputation for his 2008 book Bad to affect doctors’ prescribing habits (although most doctors claim Science and his column in the Guardian newspaper of the same that their own practices have never been affected, just those of their name. In both he provides an entertaining, accessible and colleagues). Even journals, which are considered to be an unbiased well-researched exposé of poor scientific practices. Compared to source of medical knowledge, are not free from this – journal articles his first book, which played charlatans such as Gillian McKeith are regularly ghost-written by employees of drug companies and an and homoeopathists for laughs, Bad Pharma is a much more eminent academic is invited to put their name to it; this appears in sombre read. However, as a piece of investigative journalism, and the journal, again without disclosure. a resource for students, doctors and patients, it is invaluable. Drugs are tested by the people who Food for thought Goldacre opens by making a claim that: “Drugs are tested by the manufacture them, in poorly designed people who manufacture them, in poorly designed trials, on trials, on hopelessly small numbers of hopelessly small numbers of weird, unrepresentative patients, and unrepresentative patients, and analysed analysed using techniques which are flawed by design, in such a way that exaggerate the benefits of treatments.
    [Show full text]
  • Drugs, Money and Misleading Evidence
    Books & arts tallying up the inequalities. She recruited colleagues to gather much more data. The culmination was a landmark 1999 study on gender bias in MIT’s school of science (see go.nature.com/2ngyiyd), which reverber- ated across US higher education and forced many administrators to confront entrenched discrimination. Yet Hopkins would rather have spent that time doing science, she relates. The third story comes from Jane Willenbring, a geoscientist who in 2016 filed a formal com- plaint accusing her PhD adviser, David March- ant, of routinely abusing her during fieldwork in Antarctica years before. Marchant, who has denied the allegations, was sacked from his post at Boston University in April 2019 after an inves- tigation. Picture a Scientist brings Willenbring together with Adam Lewis, who was also a grad- uate student during that Antarctic field season and witnessed many of the events. Their conver- sations are a stark reminder of how quickly and how shockingly the filters that should govern work interactions can drop off, especially in UPRISING, LLC Biologist Nancy Hopkins campaigned for equal treatment at work for female scientists. remote environments. Lewis tells Willenbring he didn’t realize at the time that she had been as they admit on camera. scientists. Its two other protagonists are white bothered, because she did not show it. “A ton The iceberg analogy for sexual harassment is women with their own compelling stories. of feathers is still a ton,” she says. apt. It holds that only a fraction of harassment — Biologist Nancy Hopkins was shocked In stark contrast, the film shows us obvious things such as sexual assault and sex- when Francis Crick once put his hands on Willenbring, now at the Scripps Institution of ual coercion — rises into public consciousness her breasts as she worked in the laboratory.
    [Show full text]
  • Pharmaceutical Marketing – Time for Change
    EJBO Electronic Journal of Business Ethics and Organization Studies Vol. 9, No. 2 Pharmaceutical Marketing – Time for Change By: Joan Buckley Introduction therapeutic options and achieve a more [email protected] equal relationship with their physicians. This paper reviews current marketing On the other hand action groups such as Abstract practices in the pharmaceutical sector, the U.S. Public Citizen’s Health Research This paper reviews current market- examining both consumer and doctor- Group oppose this practice as they con- oriented promotion. It presents examples tend that there is no evidence that such ing practices in the pharmaceutical of marketing practices and their impact advertising improves health care. sector, and their impact on consumer on consumer and doctor behaviour. It For marketers it is perhaps a difficult and doctor behaviour. It identifies identifies negative impacts of these prac- area to engage with, given that Big Phar- negative impacts which include tices which include misleading advertis- ma is in many ways the ultimate market- misleading advertising, disease ing, disease mongering and escalating ing example. They engage in multi-mil- mongering and escalating costs. It costs. It goes on to argue the need for an lion dollar marketing campaigns, use all independently-monitored code of prac- methods of promotion from mass media argues the need to move from indus- tice for marketers in the pharmaceutical advertising, to below the line spend on try self-regulation to an independ- sector and a greater degree of consumer measures such as the engagement of key ently monitored code of practice for education for both end-users and those opinion leaders.
    [Show full text]
  • “The Hidden Manipulation: the Influence of Pharmaceutical Companies on Physicians and Researchers” by Shivankar Vajinepalli
    “The Hidden Manipulation: The Influence of Pharmaceutical Companies on Physicians and Researchers” By Shivankar Vajinepalli The Undergraduate Research Writing Conference • 2020 • Rutgers, The State University of New Jersey The Hidden Manipulation: The Influence of Pharmaceutical Companies on Physicians and Researchers Shivankar Vajinepalli Professor Kathleen Wilford Research in Disciplines: Science, Medicine, and Society 2 May 2019 Vajinepalli 1 Abstract Pharmaceutical companies spend a significant amount of money on physician advertising and industry sponsored research. Involvement from pharmaceutical companies in these areas can divert the focus away from patient safety and causes changes in prescribing behavior and can cause the “funding effect.” Therefore, it can be concluded that industry involvement in research and physician marketing does negatively impact patient safety, and the relationship between physicians, researchers and the industry should not be eliminated, but more strictly regulated. When physicians are visited by pharmaceutical sales representatives (PSR), their prescribing habits are negatively affected. PSRs also do not provide accurate information to physicians about medications, and therefore physician advertising should be more strictly regulated to protect patients. Possible solutions such as providing federally funded PSRs and licensing PSRs to improve the quality of information they provide should be implemented not to eliminate, but to control physician advertising. Industry presence in research causes bias in designing and publishing research studies. The funding effect causes industry funded research to report greater benefits and safety of the medications being studied. Bias in research and lack of laws regulating disclosures of conflicts of interests also raise questions about the authenticity of studies published in medical journals. Since research cannot continue without the funding from pharmaceutical companies, they should continue to fund research, but strict ethical regulations should be followed.
    [Show full text]