Services Or Infrastructure: Why We Need a Network Service Model
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Genomics As a Service: a Joint Computing and Networking Perspective
1 Genomics as a Service: a Joint Computing and Networking Perspective G. Reali1, M. Femminella1,4, E. Nunzi2, and D. Valocchi3 1Dept. of Engineering, University of Perugia, Perugia, Italy 2Dept. of Experimental Medicine, University of Perugia, Perugia, Italy 3Dept. of Electrical and Electronic Engineering, UCL, London, United Kingdom 4Consorzio Interuniversitario per le Telecomunicazioni (CNIT), Italy Abstract—This paper shows a global picture of the deployment intense research. At that time, although the importance of of networked processing services for genomic data sets. Many results was clear, the possibility of handling the human genome current research and medical activities make an extensive use of as a commodity was far from imagination due to costs and genomic data, which are massive and rapidly increasing over time. complexity of sequencing and analyzing complex genomes. They are typically stored in remote databases, accessible by using Internet connections. For this reason, the quality of the available Today the situation is different. The progress of DNA network services could be a significant issue for effectively (deoxyribonucleic acid) sequencing technologies has reduced handling genomic data through networks. A first contribution of the cost of sequencing a human genome, down to the order of this paper consists in identifying the still unexploited features of 1000 € [2]. Since the decrease of these costs is faster that the genomic data that could allow optimizing their networked Moore’s law [4], two main consequences are expected. First, it management. The second and main contribution is a is easy to predict that in few years a lot of applicative and methodological classification of computing and networking alternatives, which can be used to deploy what we call the societal fields, including academia, business, and public health Genomics-as-a-Service (GaaS) paradigm. -
A DATA-ORIENTED NETWORK ARCHITECTURE Doctoral Dissertation
TKK Dissertations 140 Espoo 2008 A DATA-ORIENTED NETWORK ARCHITECTURE Doctoral Dissertation Teemu Koponen Helsinki University of Technology Faculty of Information and Natural Sciences Department of Computer Science and Engineering TKK Dissertations 140 Espoo 2008 A DATA-ORIENTED NETWORK ARCHITECTURE Doctoral Dissertation Teemu Koponen Dissertation for the degree of Doctor of Science in Technology to be presented with due permission of the Faculty of Information and Natural Sciences for public examination and debate in Auditorium T1 at Helsinki University of Technology (Espoo, Finland) on the 2nd of October, 2008, at 12 noon. Helsinki University of Technology Faculty of Information and Natural Sciences Department of Computer Science and Engineering Teknillinen korkeakoulu Informaatio- ja luonnontieteiden tiedekunta Tietotekniikan laitos Distribution: Helsinki University of Technology Faculty of Information and Natural Sciences Department of Computer Science and Engineering P.O. Box 5400 FI - 02015 TKK FINLAND URL: http://cse.tkk.fi/ Tel. +358-9-4511 © 2008 Teemu Koponen ISBN 978-951-22-9559-3 ISBN 978-951-22-9560-9 (PDF) ISSN 1795-2239 ISSN 1795-4584 (PDF) URL: http://lib.tkk.fi/Diss/2008/isbn9789512295609/ TKK-DISS-2510 Picaset Oy Helsinki 2008 AB ABSTRACT OF DOCTORAL DISSERTATION HELSINKI UNIVERSITY OF TECHNOLOGY P. O. BOX 1000, FI-02015 TKK http://www.tkk.fi Author Teemu Koponen Name of the dissertation A Data-Oriented Network Architecture Manuscript submitted 09.06.2008 Manuscript revised 12.09.2008 Date of the defence 02.10.2008 Monograph X Article dissertation (summary + original articles) Faculty Information and Natural Sciences Department Computer Science and Engineering Field of research Networking Opponent(s) Professor Jon Crowcroft Supervisor Professor Antti Ylä-Jääski Instructor(s) Dr. -
Architecture Overview
ONAP Architecture Overview Open Network Automation Platform (ONAP) Architecture White Paper 1 Introduction The ONAP project addresses the rising need for a common automation platform for telecommunication, cable, and cloud service providers—and their solution providers—to deliver differentiated network services on demand, profitably and competitively, while leveraging existing investments. The challenge that ONAP meets is to help operators of telecommunication networks to keep up with the scale and cost of manual changes required to implement new service offerings, from installing new data center equipment to, in some cases, upgrading on-premises customer equipment. Many are seeking to exploit SDN and NFV to improve service velocity, simplify equipment interoperability and integration, and to reduce overall CapEx and OpEx costs. In addition, the current, highly fragmented management landscape makes it difficult to monitor and guarantee service-level agreements (SLAs). These challenges are still very real now as ONAP creates its fourth release. ONAP is addressing these challenges by developing global and massive scale (multi-site and multi-VIM) automation capabilities for both physical and virtual network elements. It facilitates service agility by supporting data models for rapid service and resource deployment and providing a common set of northbound REST APIs that are open and interoperable, and by supporting model-driven interfaces to the networks. ONAP’s modular and layered nature improves interoperability and simplifies integration, allowing it to support multiple VNF environments by integrating with multiple VIMs, VNFMs, SDN Controllers, as well as legacy equipment (PNF). ONAP’s consolidated xNF requirements publication enables commercial development of ONAP-compliant xNFs. This approach allows network and cloud operators to optimize their physical and virtual infrastructure for cost and performance; at the same time, ONAP’s use of standard models reduces integration and deployment costs of heterogeneous equipment. -
ISTORE: Introspective Storage for Data-Intensive Network Services
ISTORE: Introspective Storage for Data-Intensive Network Services Aaron Brown, David Oppenheimer, Kimberly Keeton, Randi Thomas, John Kubiatowicz, and David A. Patterson Computer Science Division, University of California at Berkeley 387 Soda Hall #1776, Berkeley, CA 94720-1776 {abrown,davidopp,kkeeton,randit,kubitron,patterson}@cs.berkeley.edu Abstract ware [8][9][10][19]. Such maintenance costs are inconsis- Today’s fast-growing data-intensive network services place tent with the entrepreneurial nature of the Internet, in heavy demands on the backend servers that support them. which widely utilized, large-scale network services may be This paper introduces ISTORE, a novel server architecture operated by single individuals or small companies. that couples LEGO-like plug-and-play hardware with a In this paper we turn our attention to the needs of the generic framework for constructing adaptive software that providers of new data-intensive services, and in particular leverages continuous self-monitoring. ISTORE exploits to the need for servers that overcome the scalability and introspection to provide high availability, performance, manageability problems of existing solutions. We argue and scalability while drastically reducing the cost and that continuous monitoring and adaptation, or introspec- complexity of administration. An ISTORE-based server tion, is a crucial component of such servers. Introspective monitors and adapts to changes in the imposed workload systems are naturally self-administering, as they can moni- and to unexpected system events such as hardware failure. tor for exceptional situations or changes in their imposed This adaptability is enabled by a combination of intelligent workload and immediately react to maintain availability self-monitoring hardware components and an extensible and performance goals. -
Framework for Path Finding in Multi-Layer Transport Networks
UvA-DARE (Digital Academic Repository) Framework for path finding in multi-layer transport networks Dijkstra, F. Publication date 2009 Document Version Final published version Link to publication Citation for published version (APA): Dijkstra, F. (2009). Framework for path finding in multi-layer transport networks. General rights It is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright holder(s), other than for strictly personal, individual use, unless the work is under an open content license (like Creative Commons). Disclaimer/Complaints regulations If you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the Library know, stating your reasons. In case of a legitimate complaint, the Library will make the material inaccessible and/or remove it from the website. Please Ask the Library: https://uba.uva.nl/en/contact, or a letter to: Library of the University of Amsterdam, Secretariat, Singel 425, 1012 WP Amsterdam, The Netherlands. You will be contacted as soon as possible. UvA-DARE is a service provided by the library of the University of Amsterdam (https://dare.uva.nl) Download date:29 Sep 2021 Frame Framework for w ork f or Path Finding in Multi-La Path Finding in Multi-Layer Transport Networks Quebec Amsterdam y er T ranspor StarLight t Netw orks CAnet StarLight MAN LAN NetherLight Fr eek Dijkstra Freek Dijkstra Framework for Path Finding in Multi-Layer Transport Networks Academisch Proefschrift ter verkrijging van de graad van doctor aan de Universiteit van Amsterdam op gezag van de Rector Magnificus Mw. -
Network‐Based Approaches for Pathway Level Analysis
Network-Based Approaches for Pathway UNIT 8.25 Level Analysis Tin Nguyen,1 Cristina Mitrea,2 and Sorin Draghici2,3 1Department of Computer Science and Engineering, University of Nevada, Reno, Nevada 2Department of Computer Science, Wayne State University, Detroit, Michigan 3Department of Obstetrics and Gynecology, Wayne State University, Detroit, Michigan Identification of impacted pathways is an important problem because it allows us to gain insights into the underlying biology beyond the detection of differ- entially expressed genes. In the past decade, a plethora of methods have been developed for this purpose. The last generation of pathway analysis methods are designed to take into account various aspects of pathway topology in order to increase the accuracy of the findings. Here, we cover 34 such topology-based pathway analysis methods published in the past 13 years. We compare these methods on categories related to implementation, availability, input format, graph models, and statistical approaches used to compute pathway level statis- tics and statistical significance. We also discuss a number of critical challenges that need to be addressed, arising both in methodology and pathway repre- sentation, including inconsistent terminology, data format, lack of meaningful benchmarks, and, more importantly, a systematic bias that is present in most existing methods. C 2018 by John Wiley & Sons, Inc. Keywords: systems biology r pathway r topology r gene network r survey r pathway analysis How to cite this article: Nguyen, T., Mitrea, C., & Draghici, S. (2018). Network-based approaches for pathway level analysis. Current Protocols in Bioinformatics, 61, 8.25.1–8.25.24. doi: 10.1002/cpbi.42 INTRODUCTION this gap is the fact that living organisms are With rapid advances in high-throughput complex systems whose emerging phenotypes technologies, various kinds of genomic are the results of multiple complex interactions data have become prevalent in most of taking place on various metabolic and signal- biomedical research. -
Architecture of Low Duty-Cycle Mechanisms Nadjib Aitsaadi, Paul Muhlethaler, Mohamed-Haykel Zayani
Architecture of low duty-cycle mechanisms Nadjib Aitsaadi, Paul Muhlethaler, Mohamed-Haykel Zayani To cite this version: Nadjib Aitsaadi, Paul Muhlethaler, Mohamed-Haykel Zayani. Architecture of low duty-cycle mecha- nisms. 2014. hal-01068788 HAL Id: hal-01068788 https://hal.archives-ouvertes.fr/hal-01068788 Submitted on 26 Sep 2014 HAL is a multi-disciplinary open access L’archive ouverte pluridisciplinaire HAL, est archive for the deposit and dissemination of sci- destinée au dépôt et à la diffusion de documents entific research documents, whether they are pub- scientifiques de niveau recherche, publiés ou non, lished or not. The documents may come from émanant des établissements d’enseignement et de teaching and research institutions in France or recherche français ou étrangers, des laboratoires abroad, or from public or private research centers. publics ou privés. GETRF delivrable 4: Architecture of low duty-cycle mechanisms Nadjib Aitsaadi, Paul M¨uhlethaler, Mohamed-Haykel Zayani Hipercom Project-Team Inria Paris-Rocquencourt February 2014 1 Contents 1 Introduction 4 2 Principlesofthearchitecture 5 2.1 Routingprotocols......................... 5 2.2 MACrendezvousprotocols. 6 2.2.1 Sender-oriented rendezvous algorithm . 6 2.2.2 Receiver-oriented rendezvous algorithms . 9 2.3 Building a low duty-cycle protocol in multihop wireless networks 9 3 Descriptionofourcontributions 10 3.1 Receiver-orientedproposal . 10 3.1.1 Description ........................ 10 3.1.2 Analyticalmodel . 12 3.1.3 Simulationresults. 15 3.2 Sender-orientedproposal . 24 3.2.1 Description ........................ 24 3.2.2 Analyticalmodel . 27 3.2.3 Simulationresults. 28 3.3 Comparisonanddiscussion . 32 4 Conclusion 34 2 3 1 Introduction A Wireless Sensor Network (WSN) is composed of sensor nodes deployed within an area to monitor predefined phenomena (e.g. -
Lesson 5: Web Based E Commerce Architecture
E-COMMERCE LESSON 5: WEB BASED E COMMERCE ARCHITECTURE Topic: other over the internet. This protocol is called the Hypertext Transfer · Introduction Protocol (HTTP). · Web System Architecture Uniform Resource Locator · Generation Of Dynamic Web Pages To identify web pages, an addressing scheme is needed. Basically, a Web page is given an address called a Uniform Resource Locator · Cookies (URL). At the application level, this URL · Summary provides the unique address for a web page, which can be treated · Exercise as an internet resource. The general format for a URL is as follows: Objectives protocol://domain_name:port/directory/resource After this lecture the students will be able to: The protocol defines the protocol being used. Here are some · Understand web based E Commerce architecture examples: All of you might have understood that web system together with · http: hypertext transfer protocol the internet forms the basic infrastructure for supporting E · https: secure hypertext transfer protocol Commerce. In this lecture we will discuss in detail what are the · ftp: file transfer protocol components a web bases system is consist of assuming that you have a knowledge of basic network architecture of the internet · telnet: telnet protocol for accessing a remote host (i.e. Layered model of the Internet) The domain_name, port, directory and resource specify the domain Web System Architecture name of the destined computer, the port number of the connection, the corresponding directory of the resource and the Figure 5.1 gives the general architecture of a web-based ecommerce requested resource, respectively. system. For example, the URL of the welcome page (main.html) of our Basically, it consists of the following components: VBS may be writ-ten as http://www.vbs.com/welcome/ · Web browser: It is the client interface. -
The Network Access Machine
NAT'L INST . OF STAND 4 TECH AlllOS T73fl?b ference National Bureau of Standards MBS Library, E-01 Admin. Bidg. Publi - cations JUN 13 1979 Q1"7 CO 186377 -&f. NBS TECHNICAL NOTE 51 I / US163 U.S. DEPARTMENT OF COMMERCE/ National Bureau of Standards A Review of Network Access Techniques with a Case Study: The Network Access Machine r~- NATIONAL BUREAU OF STANDARDS 1 The National Bureau of Standards was established by an act of Congress March 3, 1901. The Bureau's overall goal is to strengthen and advance the Nation's science and technology and facilitate their effective application for public benefit. To this end, the Bureau conducts research and provides: (1) a basis for the Nation's physical measurement system, (2) scientific and technological services for industry and government, (3) a technical basis for equity in trade, and (4) technical services to promote public safety. The Bureau consists of the Institute for Basic Standards, the Institute for Materials Research, the Institute for Applied Technology, the Institute for Computer Sciences and Technology, and the Office for Information Programs. THE INSTITUTE FOR BASIC STANDARDS provides the central basis within the United States of a complete and consistent system of physical measurement; coordinates that system with measurement systems of other nations; and furnishes essential services leading to accurate and uniform physical measurements throughout the Nation's scientific community, industry, and commerce. The Institute consists of the Office of Measurement Services, the Office of Radiation Measurement and the following Center and divisions: Applied Mathematics — Electricity — Mechanics — Heat — Optical Physics — Center " for Radiation Research: Nuclear Sciences; Applied Radiation — Laboratory Astrophysics " " = — Cryogenics — Electromagnetics — Time and Frequency . -
Intent NBI for Software Defined Networking
Intent NBI for Software Defined Networking Intent NBI for Software Defined Networking 1 SDN NBI Challenges According to the architecture definition in Open Networking Foundation (ONF), a Software Defined Network (SDN) includes three vertically separated layers: infrastructure, control and application. The North-Bound Interface (NBI), located between the control plane and the applications, is essential to enable the application innovations and nourish the eco-system of SDN by abstracting the network capabilities/information and opening the abstract/logic network to applications. Traditional NBI used to pay more attention on the function layer. The Functional NBI is usually designed by the network domain experts from the network system point of view. The network capabilities are abstracted and encapsulated from bottom up. This kind of design does not take care of the requirement from user side, but expose network information and capability as much as possible. In this way, applications can get maximum programmability from the functional NBI. The examples of functional NBI include: device and link discovery, ID assignment for network interfaces, configuration of forwarding rules, and management of tens of thousands of network state information. However, let’s look from the application developer’s point of view, and assume that they are not familiar with the complex network concepts and configurations. The application developers want to focus on the functionality of the application and the friendly interaction with application users. The network service is required to be used as easy and automatic as the cloud services. The network function is required to be flexible, available and scalable. All this requires the network to have a set of service oriented, declarative, and intent based NBI. -
Research on Network Architecture of the E-Commerce Platform and Optimization of the System Performance
Send Orders for Reprints to [email protected] 2266 The Open Cybernetics & Systemics Journal, 2015, 9, 2266-2271 Open Access Research on Network Architecture of the E-commerce Platform and Optimization of the System Performance Zhanwei Chen* College of Computer Science and Technology, Zhoukou Normal University, Zhoukou 466001, Henan, China Abstract: With the rapid development of computer technology, especially the rapid development of network technology and the acceleration of global economic integration, electronic commerce has been used more and more widely. This also puts forward a new standard for the enterprise application computer to business activities. On one hand, we should take into account the advanced nature of the electronic commerce platform, on the other hand, we should make the existing business system of the enterprise more smoothly into the new business platform. Aiming at the problem of resource bot- tleneck in current e-commerce system, the application model of grid based electronic commerce system is put forward to be based on the application background of grid technology. How to make full use of the existing software and hardware resources, to obtain the largest data processing capacity has become an important part of the electronic commerce plat- form application system. Keywords: Electronic commerce, framework, grid, system optimization. 1. INTRODUCTION network transactions and online electronic payment and a variety of business activities, trading activities, financial With the rapid development of economic globalization activities and comprehensive service activities without the and the rapid development of Internet technology, e- meeting between the buyers and sellers, in a wide range of commerce which is a new business model has been the commercial and trading activities around the world, in the world's attention and recognition. -
Designing Cisco Network Service Architectures (ARCH)
Data Sheet Learning Services Cisco Training on Demand Designing Cisco Network Service Architectures (ARCH) Overview Designing Cisco® Network Service Architectures (ARCH) Version 3.0 is a Cisco Training on Demand course. It enables you to perform the conceptual, intermediate, and detailed design of a network infrastructure that supports desired network solutions over intelligent network services to achieve effective performance, scalability, and availability. It also enables you to provide viable, stable enterprise internetworking solutions by applying solid Cisco network solution models and recommended design practices. By building on the Designing for Cisco Internetwork Solutions (DESGN) Version 3.0 course, you learn additional aspects of modular campus design, advanced addressing and routing designs, WAN service designs, enterprise data center, and security designs. Interested in purchasing this course in volume at discounts for your company? Contact [email protected]. Duration The ARCH Training on Demand is a self-paced course based on the 5-day instructor-led training version. It consists of 40 sections of instructor video and text totaling more than 28 hours of instruction along with interactive activities, 7 hands-on lab exercises, content review questions, and challenge questions. Target Audience This course is designed for network engineers and those preparing for the 300-320 ARCH exam. © 2016 Cisco and/or its affiliates. All rights reserved. This document is Cisco Public Information. Page 1 of 4 Objectives After completing