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1 International Symposium on Carcinogenic Spiral & 9 1st International Symposium on Carcinogenic Spiral & 9th International Conference on Protein Phosphatase February 1 (Tue) – 3 (Thu), 2011 Tetsumon Memorial Hall, The University of Tokyo, Japan Organizer Masanori HATAKEYAMA, M.D. Ph.D. 1 Welcoming Address Welcome to the Joint Meeting of the 1st International Symposium on Carcinogenic Spiral and the 9th International Conference on Protein Phosphatase. As the organizer, I am delighted to host many eminent scholars from Japan as well as overseas. During the Conference, you will be able to learn about exciting up-to-date discoveries in the field of protein phosphatase research. I also would like to emphasize that the second day of the conference will provide a unique scientific opportunity that admixes cutting-edge research on tyrosine phosphatases with cutting-edge research on infection, inflammation and cancer. This special session was made possible by the generous support from Scientific Research on Innovative Areas, a MEXT Grant-in Aid Project. I hope that all of the participants will benefit from valuable scientific information and fruitful discussions throughout the 3-day Conference. I would like to again express a warm-hearted welcome to all of you gathered here. I also express my special thanks to those who have taken time out of their busy schedule to be here. I hope that all of the participants enjoy the Conference and also enjoy Tokyo, a city with lots of fun and excitement. Best regards, Masanori Hatakeyama, M.D., Ph.D. Organizer 1st International Symposium on Carcinogenic Spiral 9th International Conference on Protein Phosphatase 2 General Information Congress 1st International Symposium on Carcinogenic Spiral & 9th International Conference on Protein Phosphatase Date February 1 (Tue) – 3 (Thu), 2011 Venue Tetsumon Memorial Hall Hongo Campus, The University of Tokyo 14th floor of Faculty of Medicine Experimental Research Bldg. 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan TEL: 81-3-5841-3408 FAX: 81-3-5841-3406 Oral Presentation Please bring a CD, a USB memory stick, or your own computer with a mini D-sub 15-pin connector. Please upload your file before your session starts. Poster Presentation A poster board, 200 cm in height and 90 cm in width, is available for each presenter. Pins are provided by organizers. Please set up your poster before the morning session and remove it after the poster session ends. Group Photo A group photo is scheduled from 12:05 following the morning session on February 2. Reception Reception will be held at Capo PELLICANO (13th floor of Faculty of Medicine Experimental Research Bldg.) from 18:30 on February 2. 3 Floor Map Faculty of Medicine Experimental Research Bldg., University of Tokyo 1st Floor Entrance Disaster Control Tetsumon Center Cafe EV EV EV EV Faculty of Medicine Bldg. 1 14th Floor Oral Presentation Poster Presentation Vaulted Ceiling (Capo PELLICANO) Front Desk TetsumonTetsumon Memorial HallHall EV EV EV EV 4 University of Tokyo, Hongo Campus Map Ikenohata Gate Faculty of Medicine Experimental Research Bldg. Asano South Gate Asano Main Gate Yayoi Gate Tatsuoka Gate Gate to Faculty Main Gate Akamon of Agriculture (Red Gate) 0 50 100 200 300 (m) Tetsumon Memorial Hall, Hongo Campus, University of Tokyo 14th floor of Faculty of Medicine Experimental Research Bldg. 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan 5 Access Map to University of Tokyo for Ohji for Toride Gate to Faculty Nezu of Agriculture Todaimae Ikenohata Gate Main The University of Tokyo Gate [Hongo Campus] Ueno Akamon Ueno for Ikebukuro (Red Gate) Tatsuoka Gate Ueno-hirokoji UNIVERSITY BUS 01 Okachimachi for Kasuga Hongo-sanchome for Kuramae UNIVERSITY Yushima Hongo-sanchome BUS 07 Ochanomizu for Meguro Ochanomizu for Chiba for Yotsuya Ochanomizu for Shinjuku Shin-ochanomizu Marunouchi Line TOKYO BUS 43 Oedo Line TOKYO Chiyoda Line for Yoyogi-uehara Namboku Line JR Line for Shinjuku Tetsumon Memorial Hall, Hongo Campus, University of Tokyo 14th floor of Faculty of Medicine Experimental Research Bldg. 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan Nearest Stations Hongo-sanchome Station (Subway Marunouchi Line) 10 min. walk Hongo-sanchome Station (Subway Oedo Line) 10 min. walk Yushima Station or Nezu Station (Subway Chiyoda Line) 15 min. walk Todaimae Station (Subway Namboku Line) 20 min. walk 6 Program February 1 (Tue) Opening Lecture Chair: !"#$#%"&!"'()*#+,$!!"#$%&'()*+,-./*0%./*)12/3*)456-78,%9 9:30-10:15 !"#($#&-,./$, !:828$#*(54;/3*<-7-59! “Regulation of Cellular Functions by PP2C Family Members” Session 1-1. Ser/Thr Phosphatase Part 1 Chairs: !"#($#&-,./$,!!:828$#*(54;/3*<-7-59! 0,%,1)&23,1,&!04%*(54;/3*<-7-59! 10:15-10:35 !,1)$/&0)4"#5,*!=#>->8?8*(54;/3*<-7-59! “Reciprocal Inhibition System between PP2A and CDK” 10:35-10:50 67/1,$)&8,9#",$,!!=#>->8?8*(54;/3*<-7-59! “Protein Phosphatase 6 Regulates Apoptosis via CaMKII and p27” * 10:50-11:05 Coffee Break 11:05-11:20 :)%"#$)&;"/.,(!!@8$$-4.8*(54;/3*<-7-59! “Suppression of Breast Cancer Cells Proliferation by Novel Inhibitor for p53-Inducible Protein Phosphatase PPM1D” 11:20-11:40 6'#+)&!/3#/$,!!=45$4*(54;/3*<-7-59 “A Powerful Genetic Strategy to Screen for Inhibitors of MAP Kinase Signalling and Its Application to Genomic Drug Discovery” Session 1-2. Dual Specific Phosphatase Chairs: <'(=!"'(3&>'(3!!(A)"3*()B9 ?#1)%"#&@,+,3,.,!!'-?C/*A-51%,*A%5?%,*D5E?/3*<-7-59! 11:40-12:00 ?#$)%"#&!"#.,!!04F-64*A-51%,*A%5?%,*G%E%-,12*D5E?/3*<-7-59! “Analysis of Protein Phosphatases in Human Glioma Patients” 12:00-12:15 !,5,1%/3/&2)+/.,!!04%*(54;/3*<-7-59! “Contribution of p38! in Blood Cells to the Regulation of Obesity and Blood Glucose Level” 12:15-13:30 Lunch / Organizing Committee 13:30-15:30 Poster Session 7 Session 1-3. Tyr Phosphatase Part 1 Chairs: A'(9,.#(&<&@''*!!H5?-,48*A-51%,*D5E?/3*A-5-.-9 -,+,%"#&0,1)B,+#&!=8I%*(54;/3*<-7-59* 15:30-16:05 0#4"'*&C&-$'.D*,7!!01+4CC*(54;/3*A-5-.-9 “Regulation and Oncogenic Activities of PTP1B” 16:05-16:20 8)%/+'&0,1%/)!!(A*"-;4E3*()B9* “Regulation of Brown Fat Adipogenesis by Protein Tyrosine Phosphatase 1B” 16:20-16:40 >,E,B&<&?,9!!(A*"-;4E3*()B9* “Differential Regulation of Endoplasmic Reticulum Stress by Protein Tyrosine Phosphatase 1B and T Cell Protein Tyrosine Phosphatase” 16:40-17:00 -B/=;"#(3&0'(3!!D5E?/*J48C8641-C*A2%>/*B1-.%>4-*)4541-3*:-4K-59 “S-Nitrosylation and Inactivation of PTPs Protects Cardiomyocytes Against Hypoxic Injury” 17:00-17:15 @,)1)&@,3,1,!!(A*"-;4E3*()B9! “Hepatic Src Homology Phosphatase 2 Regulates Energy Balance and Metabolism” 8 February 2 (Wed) Keynote Lecture Chair: 0,%,()$#&?,1,+'7,.,!!(54;/*:8$F83*<-7-59 9:00-9:45 @#4")*,%&8&-)(+%*!A8C.*)7,456*@-,I8,*L-I/3*()B9! “Functional Analysis of Protein Tyrosine Phosphatases” Session 2-1. Carcinogenic Spiral Part 1 Chairs: 0,%,)&0,1%/)+,!!=F8?8*(54;/3*<-7-59 8/(#1,5,&!"#.)1)"()!!A24I-*D5E?/*:%12/3*<-7-59! 9:45-10:20 0,%,()D/&2%"#.,!!=-5-M-K-*(54;/3*<-7-59* “Prostaglandin E2-Associated Inflammation and Bacterial Infection in Gastric Tumorigenesis” 10:20-10:55 F,G#5&0&H#$%"/I!!"#$%&'()*+,-./*0%./*)12/3*)456-78,%9 “Posttranslational Regulation of the Wnt Signaling Pathway” * 10:55-11:10 Coffee Break Session 2-2. Carcinogenic Spiral Part 2 Chairs: 8,B/(,$#&J+#7)%"#!!=F8?8*(54;/3*<-7-59 -,5,1%/3/&-,(#3/4"#!!(54;/*:8$F83*<-7-59! 11:10-11:45 8/(#1,5,&!"#.)1)"()!!A24I-*D5E?/*8N*:%1258C86F3*<-7-59 “Dys-regulation of Lipid Metabolism May Link to the Development of Hepatocellular Carcinoma” 11:45-12:20 0,%,)&0,1%/)+,*!=F8?8*(54;/3*<-7-59 “Immunological Dysregulation and Oncogenesis by Human T-Cell Leukemia Virus Type 1” 12:20-12:30 Group Photo 12:30-14:00 Lunch 9 Special Lecture Chair: F,G#5&0&H#$%"/I!!"#$%&'()*+,-./*0%./*)12/3*)456-78,%9 14:00-14:45 -,5,1%/3/&-,(#3/4"#*!(54;/*:8$F83*<-7-59 “Regulation of Immune Responses and Oncogenesis by the IRF Family of Transcription Factors and Their Partners” Session 2-3. Carcinogenic Spiral part 3 Chairs: 0,%,()D/&2%"#.,*!=-5-M-K-*(54;/3*<-7-59 -,+'%"#&JB/.,!!=8I%*(54;/3*<-7-59! 14:45-15:20 -%/+,%,&!'7,!!@8$$-4.8*(54;/3*<-7-59 “Functional Divergence of RNA-Sensing Systems in Dendritic Cells for Induction of Antitumor Effectors” 15:20-15:55 8,B/(,$#&J+#7)%"#&!=F8?8*(54;/3*<-7-59 “Polysaccharide Nanogel DDS for Cancer Immunotherapy” 15:55-16:10 Coffee Break Session 2-4. Carcinogenic Spiral Part 4 Chairs: @#4")*,%&8&-)(+%*!A8C.*)7,456*@-,I8,*L-I/3*()B9! -%/+,%,&!'7,!!@8$$-4.8*(54;/3*<-7-59* 16:10-16:45 A'(9,.#(&<&@''**!H5?-,48*A-51%,*D5E?/3*A-5-.-9 “Tyrosine Phosphatases in Health and Disease” 16:45-17:20 0,%,()$#&?,1,+'7,.,!!(54;/*:8$F83*<-7-59 “Role of SHP2 Tyrosine Phosphatase in Gastric Carcinogenesis” 17:20-17:55 <'(=!"'(3&>'(3!!(A)"3*()B9 “Identification of PTPN11/Shp2 as a Tumor Suppressor in Liver Cancer” 17:55-18:30 -,+'%"#&JB/.,*!=8I%*(54;/3*<-7-59 “Helicobacter pylori Infection and Gastric Cancer: Relationship between Gastric Cancer and Diversity of Helicobacter pylori” 18:30-20:30 Reception 10 February 3 (Thu) Session 3-1.Tyr Phosphatase Part 2 Chairs: 0#4"'*&C&-$'.D*,7!!01+4CC*(54;/3*A-5-.-9! -,+'%"#&-%/D,1,!!:8$F8*0%.41-C*O*"%5?-C*(54;/3*<-7-59* 9:00-9:35 -,+,%"#&0,1)B,+#&!=8I%*(54;/3*<-7-59 “Regulation of Intestinal Immunity by SAP-1, a Microvillus-Specific Receptor-Type Protein Tyrosine Phosphatase” 9:35-10:10 K#&L",(3!!(A)"3*()B9 “Beyond Insulin Secretion: Substrate Identification of a Mitochondrial Phosphatase” 10:10-10:25 0/('.,%,&0)$#!!+#5>-*(54;/3*<-7-59 “Shear Stress Regulates Cellular Localization of Vascular Endothelial–Protein Tyrosine Phosphatase (VE-PTP)” 10:25-10:45 -)%"#)&M,1,(,D'!!'-,-*P8>%5QE*(54;/3*<-7-59 “Phospho-Paxillin Is an Oncogenic in Vivo Target of the Tumor Suppressor Receptor Protein Tyrosine Phosphatase T” 10:45-11:00 Coffee Break Session 3-2.
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