MMP17 Rabbit Pab

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Leader in Biomolecular Solutions for Life Science MMP17 Rabbit pAb Catalog No.: A3030 Basic Information Background Catalog No. This gene encodes a member of the peptidase M10 family and membrane-type A3030 subfamily of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as Observed MW embryonic development, reproduction, and tissue remodeling, as well as in disease 75kDa processes, such as arthritis and metastasis. Members of this subfamily contain a transmembrane domain suggesting that these proteins are expressed at the cell surface Calculated MW rather than secreted. The encoded preproprotein is proteolytically processed to 57kDa/66kDa generate the mature protease. This protein is unique among the membrane-type matrix metalloproteinases in that it is anchored to the cell membrane via a Category glycosylphosphatidylinositol (GPI) anchor. Elevated expression of the encoded protein has been observed in osteoarthritis and multiple human cancers. Primary antibody Applications WB, IHC Cross-Reactivity Human, Mouse, Rat Recommended Dilutions Immunogen Information WB 1:500 - 1:2000 Gene ID Swiss Prot 4326 Q9ULZ9 IHC 1:50 - 1:200 Immunogen A synthetic peptide of human MMP17 Synonyms MMP17;MMP-17;MT4-MMP;MT4MMP;MTMMP4 Contact Product Information www.abclonal.com Source Isotype Purification Rabbit IgG Affinity purification Storage Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. Validation Data Western blot analysis of extracts of various cell lines, using MMP17 Rabbit pAb (A3030) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. Immunohistochemistry of paraffin- Immunohistochemistry of paraffin- embedded Human colon using MMP17 embedded Mouse brain using MMP17 Rabbit pAb (A3030) at dilution of 1:100 Rabbit pAb (A3030) at dilution of 1:100 (40x lens). (40x lens). Antibody | Protein | ELISA Kits | Enzyme | NGS | Service For research use only. Not for therapeutic or diagnostic purposes. Please visit http://abclonal.com for a complete listing of recommended products..

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Smooth Muscle-Specific MMP17 (MT4-MMP) Defines the Intestinal ECM Niche 2 3 Mara Martín-Alonso1*, Håvard T
bioRxiv preprint doi: https://doi.org/10.1101/2020.06.18.147769; this version posted June 18, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder. All rights reserved. No reuse allowed without permission. 1 Smooth muscle-specific MMP17 (MT4-MMP) defines the intestinal ECM niche 2 3 Mara Martín-Alonso1*, Håvard T. Lindholm1,# , Sharif Iqbal2,3,#, Pia Vornewald1#, Sigrid Hoel1, 4 Mirjam J. Damen4, A.F.Maarten Altelaar4, Pekka Katajisto2,3,5, Alicia G. Arroyo6,7, Menno J. 5 Oudhoff1* 6 7 1CEMIR – Centre of Molecular Inflammation Research, Department of Clinical and Molecular 8 Medicine, NTNU – Norwegian University of Science and Technology, 7491 Trondheim, 9 Norway 10 2Institute of Biotechnology, HiLIFE, University of Helsinki, Finland 11 3Molecular and Integrative Bioscience Research Programme, Faculty of Biological and 12 Environmental Sciences, University of Helsinki, Helsinki, Finland 13 4Biomolecular Mass Spectrometry and Proteomics, Utrecht University, Utrecht, The 14 Netherlands 15 5Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden 16 6Centro de Investigaciones Biológicas Margarita Salas (CIB-CSIC), Madrid, Spain 17 7Vascular Pathophysiology Area, Centro Nacional de Investigaciones Cardiovasculares 18 (CNIC), Madrid, Spain.CNIC, Madrid, Spain 19 20 #These authors contributed equally to this work 21 *corresponding authors, e-mail: [email protected], [email protected] 22 bioRxiv preprint doi: https://doi.org/10.1101/2020.06.18.147769; this version posted June 18, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder. All rights reserved. No reuse allowed without permission.
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Koch Shrna Gene Webpage
Symbol SEPT9 ADAM30 AEN AMBP ARHGEF12 ATG16L2 BCAS3 A1CF ADAM32 AFF3 AMBRA1 ARHGEF17 ATG2A BCKDK AAK1 ADAM33 AGAP2 AMHR2 ARHGEF2 ATG3 BCL10 AATK ADAM7 AGER AMPH ARHGEF4 ATG4B BCL11A ABCA1 ADAM8 AGK ANAPC2 ARHGEF6 ATG4C BCL11B ABCA3 ADAM9 AGL ANG ARHGEF7 ATG4D BCL2 ABCB1 ADAMDEC1 AGPAT9 ANGPT2 ARID1A ATG5 BCL2L1 ABCB4 ADAMTS1 AGR3 ANGPTL4 ARID1B ATG7 BCL2L11 ABCC1 ADAMTS10 AHR ANKK1 ARID2 ATM BCL2L2 ABCC10 ADAMTS12 AIMP2 ANKRD30A ARID3A ATMIN BCL3 ABCC2 ADAMTS13 AIP ANO1 ARID3B ATP1B3 BCL6 ABCG2 ADAMTS14 AJAP1 ANXA1 ARID4B ATP2B4 BCL7A ABI1 ADAMTS15 AK1 ANXA2 ARID5A ATP7A BCL9 ABL1 ADAMTS16 AK2 ANXA6 ARID5B ATP7B BCR ABL2 ADAMTS17 AK3 ANXA7 ARL11 ATR BECN1 ACIN1 ADAMTS18 AK4 APAF1 ARNT ATRX BFAR ACP1 ADAMTS19 AK5 APC ARSB ATXN1 BIK ACPP ADAMTS2 AK7 APCDD1 ARSG ATXN2 BIN1 ACSL4 ADAMTS20 AK8 APEX1 ASAP1 AURKA BIN2 ACTN1 ADAMTS3 AKAP1 APOBEC1 ASAP3 AURKB BIRC2 ACVR1 ADAMTS4 AKAP13 APOBEC2 ASB15 AURKC BIRC3 ACVR1B ADAMTS5 AKAP3 APOBEC3G ASCC1 AXIN1 BIRC5 ACVR1C ADAMTS7 AKAP8L AQP1 ASCC3 AXIN2 BIRC7 ACVR2A ADAMTS8 AKR1B10 AQP5 ASCL1 AXL BLCAP ACVR2B ADAMTS9 AKR1C1 AQP7 ASCL2 AZGP1 BLK ACVRL1 ADAR AKR1C3 AR ASF1A BACE1 BLM AD026 ADARB1 AKT1 ARAF ASH1L BAD BMI1 ADAM10 ADARB2 AKT2 AREG ASH2L BAG1 BMP2 ADAM11 ADAT2 AKT3 ARF1 ASNS BAG4 BMP2K ADAM12 ADCK1 ALCAM ARF4 ASPH BANF1 BMP2KL ADAM15 ADCK2 ALDH18A1 ARF5 ASPSCR1 BAP1 BMPR1A ADAM17 ADCK3 ALK ARF6 ASS1 BARD1 BMPR1B ADAM18 ADCK4 ALKBH2 ARHGAP12 ASTE1 BAX BMPR2 ADAM19 ADCK5 ALKBH3 ARHGAP22 ASXL1 BAZ1A BMX ADAM2 ADCY6 ALKBH8 ARHGAP25 ATF1 BAZ1B BNIP3 ADAM20 ADK ALOX15 ARHGAP26 ATF2 BAZ2A BPTF ADAM21
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