Animal Worker Health & Safety
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Airborne Allergens--Something in the Air Cover Illustration
Airborne Allergens SOMETHING IN THE AIR U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute of Allergy and Infectious Diseases Airborne Allergens SOMETHING IN THE AIR U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute of Allergy and Infectious Diseases NIH Publication No. 03-7045 April 2003 www.niaid.nih.gov Contents 1 Introduction 4 Symptoms 6 Pollen Allergy 10 Mold Allergy 14 Dust Mite Allergy 16 Animal Allergy 17 Chemical Sensitivity 18 Diagnosis 20 Prevention 25 Treatment 28 Allergy Research 32 Glossary 34 More Information Introduction Sneezing is not always the symptom of a cold. Sometimes, it is an allergic reaction to something in the air. Health experts estimate that 35 million Americans suffer from upper respiratory tract symptoms that are allergic reactions to airborne allergens. Pollen allergy, commonly called hay fever, is one of the most common chronic diseases in the United States. Worldwide, airborne allergens cause the most problems for people with allergies. The respiratory symptoms of asthma, which affect approximately 11 million Americans, are often provoked by airborne allergens. Overall, allergic diseases are among the major causes of illness and disability in the United States, affecting as many as 40 to 50 million Americans. The National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health (an agency of the U.S. Department of Health and Human Services) supports and conducts research on allergic diseases. The goals of this research are to provide a better understanding of the causes of allergy, to improve methods for diagnosing and treating allergic reactions, and eventually to prevent allergies. -
Animal Model of Allergy and Asthma; Protocol for Researches
Animal model of allergy and asthma; protocol for researches Seyyede Masoume Athari Entezar Mehrabi Nasab Seyyed Shamsadin Athari ( [email protected] ) Department of Immunology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran https://orcid.org/0000-0002-6355-6378 Method Article Keywords: Allergic diseases, Asthma, Immune system, Model, Animal Posted Date: September 11th, 2019 DOI: https://doi.org/10.21203/rs.2.13928/v1 License: This work is licensed under a Creative Commons Attribution 4.0 International License. Read Full License Page 1/17 Abstract Allergic diseases and asthma are an important problem in health system and effects large amounts of people in the worlds. Exposure to outdoor and indoor allergens promote the sensitization towards these allergens. Th2 cytokines are main stimulators allergic diseases initiation. Allergic diseases similar to other diseases have been studied in animal for understanding of pathophysiology and treatments. Animal models provide a potential approach to investigation of the pathophysiology, mechanism and drugs designing for allergy and asthma. Physicians and veterinarians with collaboration in this eld could improve best animal model. In this review, it will be discussed the various models (especially in mouse) and protocols by focusing on the allergic diseases. Animal models in allergy eld, are applicable for important goals. Moral discussion in all procedures should be remarkable. Introduction 1. Introduction Allergic diseases are a common problem in all countries and effects large amounts of people in the worlds (1). Allergic diseases and asthma affect up to 20% of the Western countries populations (2). Allergic disease are relapsing in nature and allergen exposure is associated with exacerbations frequently. -
The Facts About Protein Our Bodies and Those of Companion Animals Are Orchestrated by Cellular Machinery, Which Is Directed Acco
The Facts About Protein Our bodies and those of companion animals are orchestrated by cellular machinery, which is directed according to blueprints of DNA. To do so, DNA is transcribed into RNA and then further translated into functional proteins or enzymes. These proteins or enzymes are present in all living cells, are critical for growth and maintenance of the body, and are essential to the well being of both humans and animals. For example, vital body functions, such as blood clotting, fluid balance, visual processes, hormone balance, enzyme activity as well as energy production, all involve proteins or enzymes. Proteins are also important structural constituents of muscle, hair, bone and organs. Our survival relies on constant adjustments to the cellular machinery, which is accomplished by fine-tuning the conversion of DNA into functional proteins. The translation of functional proteins and their ability to perform optimally require a readily available supply of amino acids, which are the building blocks of protein. Although proteins are considered essential for healthy dogs and cats, it is not actually dietary proteins that are utilized by the body, but rather the constituent amino acids, which make up dietary protein. Proteins are made up of hundreds of amino acids. The body utilizes twenty (in dogs) or 21 (in cats) common amino acids in various combinations. While each of these amino acids are important for growth, maintenance and health of the body, some of are considered essential amino acids and others non- essential. Essential amino acids cannot be manufactured by the body from precursors and, therefore, must be provided by the diet. -
Laboratory Animal Allergy: an Update
Laboratory Animal Allergy: An Update Robert K. Bush and Gregg M. Stave Abstract Key Words: allergens; allergy; animal allergy; asthma; laboratory animal allergy; laboratory animals; occupational Allergic reactions are among the most common conditions health affecting the health of workers involved in the care and use of research animals. Between 11 and 44% of the individuals Epidemiology of Laboratory Animal working with laboratory animals report work-related aller- Allergy (LAA1) gic symptoms. Of those who become symptomatic, 4 to 22% may eventually develop occupational asthma that can stimates of the number of individuals exposed to labo- persist even after exposure ceases. Allergic symptoms con- ratory animals in their occupation vary considerably. sist of rashes where animals are in contact with the skin, EBland and colleagues (1987) estimated that 90,000 nasal congestion and sneezing, itchy eyes, and asthma individuals were exposed to laboratory animals in the (cough, wheezing, and chest tightness). The generation of United States, and 32,000 workers were similarly exposed immunoglobulin E (IgE) antibodies is a prerequisite for the in the United Kingdom. Seward (1999) estimated that production of allergic symptoms. The mechanism by which 40,000 to 125,000 individuals are exposed to laboratory IgE antibodies develop is becoming clearer. The propensity animals in the United States. to produce IgE is genetically determined, and pre-existing The existence of different definitions of LAA used in allergy may be a risk factor for the development of labora- published studies (reported symptoms vs. laboratory evi- tory animal allergy (LAA). However, exposure to animal dence of immunoglobulin E [IgE1]-mediated sensitivity) allergens is the major risk factor for the development of leads to significant variability in the reported prevalence LAA. -
Airborne Allergens--Something in the Air Cover Illustration
Airborne Allergens SOMETHING IN THE AIR U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute of Allergy and Infectious Diseases Airborne Allergens SOMETHING IN THE AIR U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute of Allergy and Infectious Diseases NIH Publication No. 03-7045 April 2003 www.niaid.nih.gov Contents 1 Introduction 4 Symptoms 6 Pollen Allergy 10 Mold Allergy 14 Dust Mite Allergy 16 Animal Allergy 17 Chemical Sensitivity 18 Diagnosis 20 Prevention 25 Treatment 28 Allergy Research 32 Glossary 34 More Information Introduction Sneezing is not always the symptom of a cold. Sometimes, it is an allergic reaction to something in the air. Health experts estimate that 35 million Americans suffer from upper respiratory tract symptoms that are allergic reactions to airborne allergens. Pollen allergy, commonly called hay fever, is one of the most common chronic diseases in the United States. Worldwide, airborne allergens cause the most problems for people with allergies. The respiratory symptoms of asthma, which affect approximately 11 million Americans, are often provoked by airborne allergens. Overall, allergic diseases are among the major causes of illness and disability in the United States, affecting as many as 40 to 50 million Americans. The National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health (an agency of the U.S. Department of Health and Human Services) supports and conducts research on allergic diseases. The goals of this research are to provide a better understanding of the causes of allergy, to improve methods for diagnosing and treating allergic reactions, and eventually to prevent allergies.