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Annual Report 2014 - 2015 Our Mission

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Annual Report 2014 - 2015 Our Mission ANNUAL REPORT 2014 - 2015 Our Mission By integrating the fields of medicine, science, engineering and technology into translational knowledge and making the resulting biomedical innovations accessible to public health, to improve the health of the most disadvantaged people in India and throughout the world. Our Vision As a networked organization linking many centers of excellence, THSTI is envisaged as a collective of scientists, engineers and physicians that will effectively enhance the quality of human life through integrating a culture of shared excellence in research, education and translational knowledge with the developing cohorts and studying the pathogenesis and the molecular mechanisms of disease to generate knowledge to complement the processes of designing interventions and technology development. CONTENTS 3 THE ORGANIZATION Society Governing Body Leadership From the Executive Director’s Desk 11 RESEARCH PROGRAMS Vaccine and Infectious Disease Research Centre Pediatric Biology Centre Centre for Biodesign and Diagnostics Policy Center for Biomedical Research Drug Discovery Research Centre Centre for Human Microbial Ecology Population Science Partnership Centre Clinical Development Services Agency 178 ACADEMIA 184 ADMINISTRATION Organization INTRAMURAL CENTRES Vaccine & Infectious Disease Research Centre (VIDRC) Pediatric Biology Centre (PBC) Centre for Biodesign & Diagnostics (CBD) Centre for Human Microbial Ecology (CHME) Policy Centre for Biomedical Research (PCBR) Drug Discovery Research Centre (DDRC) PARTNERSHIP CENTRE Population Science Partnership Centre (PSPC) EXTRAMURAL CENTRE Clinical Development Services Agency (CDSA) THSTI Society 1 2 3 4 5 6 7 8 9 10 11 12 1. Dr. G. Padmanaban 5. Dr. T.S. Rao 9. Dr. J. Gowrishankar Distinguished Professor, Nodal Officer, THSTI, Sr. Advisor, Director, IISc Bangalore Department of Biotechnology, Centre for DNA Fingerprinting President New Delhi & Diagnostics, Member Ex-officio Hyderabad 2. Dr. K. VijayRaghavan Member Secretary, 6. Dr. Chandrima Shaha Department of Biotechnology Director, 10. Dr. B. Ravindran Govt. of India, National Institute of Director, Institute of Life New Delhi Immunology, Sciences, Bhubaneshwar Member Ex-officio New Delhi Member Member Ex-officio 3. Dr. V.M. Katoch 11. Dr. G.C. Mishra Secretary, DHR and DG ICMR, 7. Dr. M. Radhakrishna Pillai Eminent Scientist, National New Delhi Director, Centre for Cell Sciences, Pune Member Ex-officio Rajiv Gandhi Centre for Member Biotechnology, 4. Mrs. Anuradha Mitra 12. Dr. G.B.Nair Thiruvananthapuram Joint Secretary and Financial Executive Director, Translational Member Advisor, Health Science and Technology Department of Biotechnology, 8. Dr. Ashok Jhunjhunwala Institute, Gurgaon New Delhi Professor, Member-Secretary Member Ex-officio Indian Institute of Technology, Chennai Member 4 THSTI Governing Body 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 1. Dr. K. VijayRaghavan 5. Dr. G. Padmanaban 9. Dr. K. Srinath Reddy 13. Mrs. Anuradha Mitra Secretary, Distinguished President, Public Joint Secretary and Department of Professor, Indian Health Foundation of Financial Advisor, Biotechnology, Institute of Science, India, Department of Government of India, Bangalore New Delhi Biotechnology, Government New Delhi Member Member of India, New Delhi Chairperson Member 6. Dr. P. N. Tandon 10. Dr. M.S. Ananth 2. Dr. V.M. Katoch President, National Ex-Director, 14. Dr. Shinjini Bhatnagar Secretary, Brain Research Centre, Indian Institute of Dean, Clinical Research, Department of Health Manesar, Gurgaon Technology, Chennai Translational Health Research & Director Member Member Science & Technology General ICMR, Institute, Gurgaon 7. Dr. T. S. Balganesh 11. Dr. Ashutosh Sharma New Delhi Member Distinguished Institute Chair Member Scientist and Head of Professor, Indian 15. Dr. Sudhanshu Vrati 3. Dr. Dinakar M. OSDD, CSIR, Institute of Dean, Academics, Salunke New Delhi Technology, Kanpur Translational Health Executive Director, Member Member Science and Technology Regional Centre Institute, Gurgaon 8. Dr. Balram Bhargava 12. Dr. T.S. Rao of Biotechnology, Member Professor, All India Nodal Officer, Gurgaon Institute of Member THSTI, Sr. Advisor, 16. Dr. G.B.Nair Member Medical Sciences, Department of Executive Director, 4. Dr. Subrata Sinha New Delhi Biotechnology, Translational Health Director, National Member Government of India, Science and Technology Brain Research Centre, New Delhi Institute, Gurgaon Manesar, Gurgaon Member Member-Secretary Member 5 THSTI Leadership G. Balakrish Nair is the Executive Director of THSTI. His prior assignment, spanning over two decades, was at the National Institute of Cholera and Enteric Diseases (NICED), Kolkata, culminating as the Institute’s Director. The tenure at NICED was bridged with a seven year stint as Director, Laboratory Sciences Division, International Centre for Diarrhoeal Diseases Research, Dhaka, Bangladesh. His contributions to the discovery of Vibrio cholerae O139 Bengal, earned him the prestigious Shanti Swarup Bhatnagar award for Medical Sciences in 1998. In his role as the head of the organization, he has brought a unique culture of gentle reshaping of scientific minds towards translational research at THSTI. He also leads the Centre for Human Microbial Ecology at THSTI. Dr. Sudhanshu Vrati did his MSc in Microbiology from G. B. Pant University of Agriculture and Technology in Pantnagar, DIIT in Biochemical Engineering from Indian Institute of Technology Delhi, and PhD in Biochemistry from the Australian National University in Canberra. He did his postdoctoral research at CSIRO Molecular Sciences in Sydney. Dr. Vrati is the Dean of THSTI responsible for its academic program and the Head of its Vaccine and Infectious Disease Research Centre. He is a virologist with research interests spanning the RNA virus replication, antivirals, and vaccine development. Dr. Vrati has won several distinctions including the National Bioscience Award, the NASI-Reliance Industries Platinum Jubilee Award, the Tata Innovation Fellowship Award, and the fellowship of the Indian Academy of Sciences and the National Science Academy of India. Professor Shinjini Bhatnagar is the Dean of Clinical Research at THSTI. She served as Senior Research Scientist and Pediatric Gastroenterologist at the Department of Pediatrics, AIIMS. She is the Head of Pediatric Biology Centre and also the co-ordinator of Centre for Biodesign and Diagnostics and the National Biodesign Alliance. In her role as the Clinical research Dean, she has brought in an innovative approach of amalgamating clinical research into biological sciences to enhance translational capacity of THSTI. Dr. Kanury Rao is the Head of Drug Discovery research Centre at THSTI. He is a faculty in the International Centre for Genetic Engineering and Biotechnology (ICGEB). A Fellow of several academies, Dr. Rao was awarded The Shanti Swarup Bhatnagar Award for Biological Sciences, in 1997. As an Adjunct Faculty in THSTI and the head of a focused product and pipeline development team of scientists, he leads the major drug discovery research program at THSTI. Dr. Sudhakar Bangera joined CDSA with experience of 21 years in diverse areas of healthcare (Hospitals and Medical Schools), global Contract Research Organisations (CRO), Academic Research Organisation (ARO), Site Management Organisation (SMO), Medical Imaging, Clinical Bioavailability and Bioequivalence (BA-BE), and a global pharmaceutical company. He is a multifaceted, dynamic healthcare and clinical research professional leading the CDSA team at THSTI. Mr. M.V. Santo is a HR and IR professional with a substantial blend of public and private enterprise experience. A specialist in organization building, his contributions to THSTI are in the multiple facets of administrative functions. He has built a team which contributes significantly to ensure seamless support to all aspects of scientific and academic activities at the Institute. 6 From the Executive Director’s Desk During the year under report, several interesting developments have taken place at THSTI. Early in February 2015, the Institute shifted en masse from its interim location in Gurgaon to the brand new magnificent campus in Faridabad. The shift is now completed and THSTI and the Regional Centre for Biotechnology are functioning from the new campus. The laboratories and all associated equipment have been installed and we are back to the bench and to our area of work. THSTI has six intramural centres, one partnership centre and an extramural centre. Two of the centres of THSTI namely Vaccine and Infectious Diseases Research Centre (VIDRC) and Pediatric Biology Centre (PBC) have completed five years and after rigorous DBT conducted evaluation followed the path as chartered by the Governing body at its 8th meeting on 18th June, 2013. One more centre namely the Centre for Biodesign and G. B. Nair in vitro Diagnostics (CBD) will be evaluated by a DBT conducted review in the course of a year. Two other centres namely Drug Discovery Research Centre (DDRC) and Centre for Human Microbial Ecology (CHME) have just completed 2 years and their performance is being reviewed. The sixth Centre of THSTI, the Policy Centre for Biomedical Research (PCBR) has been recently reviewed by the Central Advisory Board and continues to be The core constitution of the part of THSTI. Collaborations with the Partnership Institute is an amalgam of Centre are escalating and the effectiveness of the extramural Clinical Development Services Agency disciplines and among our (CDSA)
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