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Drug Conjugates for Directed Therapy” General Information Arrival 5th Int. CeBiTec Research Conference MAGICBULLET consortium and scientific committee of By car, you can take the A2 Dortmund - Hannover, the 5th International CeBiTec Research Conference: exit at "Bielefeld-Zentrum", follow the street signs towards the center ("Zentrum"), and from there Cesare (Universitá degli Studi di Milano, IT) Gennari follow the signs to "Werther". From the "Werther- Pirjo (University of Helsinki, FI) Laakkonen straße", the ZiF is on the left side on the slope of Gábor (Eőtvős Loránd University Budapest, HU) Mező the hill. The entrance is signposted. Drug Conjugates Ines (University of Cologne, DE) Neundorf Bielefeld can be reached from any major town by Andreas (Heidelberg Pharma GmbH, Ladenburg, DE) Pahl trains running on an hourly schedule (Eurocity train for Jan (Heidelberg Pharma GmbH, Ladenburg, DE) Anderl system: marked EC, IC, or ICE on the train schedu- Umberto (Universitá degli Studi dell’ Insubria, IT) Piarulli le). From Bielefeld's main station you can either Directed Therapy Norbert (Bielefeld University (Co-ordinator), DE) Sewald take a taxi to the ZiF (approx. EUR 10,-) or take the Christian (Exiris, Rome, IT) Steinkühler underground tram line 4 (destination "Universität" József Tóvári (National Institute of Oncology, Budapest, HU) or "Lohmannshof"). From the tram stop "Universi- Registration tät" you can reach the ZiF by walking up the hill For details regarding registration please visit behind the main building of the university (the way www.magicbullet.de is signposted). Location Center for Interdisciplinary Research (ZiF) Methoden 1, 33615 Bielefeld http://www.uni-bielefeld.de/ZiF Accommodation You are encouraged to book your accommodation in the Park Inn conference hotel, which provide special rates for conference participants. Please make your reservations mentioning group reference 24421 at Park Inn by Radisson Bielefeld Telephone: +49 521 9238-0 Fax: +49 521 9238-250 Email: [email protected] September 20th – 23rd, 2015 Center for Interdisciplinary Research (ZiF) Further Information Bielefeld University, Germany For further information please contact [email protected] www.magicbullet.de www.magicbullet.de www.magicbullet.de Invitation Programme Programme The Center for Biotechnology (CeBiTec) of Bielefeld Confirmed plenary speakers Hans-Georg Lerchen Bayer, DE University cordially invites you to attend the 5th Inter- Targeted drug conjugates: Challenges in the interface between Heidelberg Pharma, DE national Bielefeld-CeBiTec Research Conference on Jan Anderl small molecules and proteins Antibody-Drug Conjugates targeting RNA polymerase II "Drug Conjugates for Directed Therapy”. The con- Marilena Manea University of Konstanz, DE University College London, UK ference will be held at the Center for Interdisciplinary James Baker Drug delivery systems containing GnRH-III peptide as a targeting The Next Generation Maleimide platform for the construction of Research (ZiF) of Bielefeld University from moiety September 20th to 23rd, 2015. homogeneous protein conjugates Gábor Mező MTA-ELTE, HU Annette Beck-Sickinger Leipzig University, DE Dual targeting with cyclic NGR peptides CeBiTec Research Conferences are annual events Targeted cancer diagnosis and therapy with peptide conjugates with thematic focus on a challenging topic in the life Ines Neundorf University of Cologne, DE sciences. The 2015 conference Drug Conjugates for Ravi J. Chari ImmunoGen, Waltham, US Organometallic bioconjugates: synthesis, cellular uptake and Directed Therapy is being organized by the Marie Antibody-Drug Conjugates: Pathway from a concept to the clinic biological activity Skłodowska-Curie European Training Network Donald M. Engelman Yale University, US Umberto Piarulli Università degli Studi dell'Insubria, IT MAGICBULLET (www.magicbullet.de), which is current- pHLIP® targeting and delivery of PNA in vivo to silence microRNA Synthesis and biological evaluation of integrin and dual integrin- ly being funded by the EU in the Horizon 2020 in acidic tumor cells VEGFR ligands for tumor targeting therapy Framework Programme for Research and Inno- Cesare Gennari Universitá degli Studi di Milano, IT Tel Aviv University, IL vation. Doron Shabat Tumor targeting via integrin ligands: Synthesis and biological tba evaluation of RGD peptidomimetic-Paclitaxel conjugates The scope of the CeBiTec Research Conference József Tóvári National Institute of Oncology, HU will include: Ulf Grawunder NBE Therapeutics, CH Application of peptid-drug conjugates in animal tumor/metastasis SMAC-Technology – generation of site-specifically conjugated models ADCs by highly efficient enzymatic conjugation • Antibody-Drug Conjugates Fred Valeriote Henry Ford Health System, Detroit, US • Peptide-Drug Conjugates Nicolas Joubert Université de Tours, FR Discovery of anticancer leads as potential drug conjugates A new chemical platform for the modular construction of homoge- • Targets and Specificity Acknowledgements • New Drugs neous Antibody-Drug Conjugates This project has received funding from the European Union’s • Linker Technologies Horst Kessler TU München, DE Horizon 2020 research and innovation programme under the • Applications Selective addressing integrin subtypes for drug research, molecular Marie Sklodowska-Curie grant agreement No 642004. • Process Development imaging and biophysical studies Felix Kratz CytRx Corporation, DE The meeting will feature plenary lectures, poster Albumin-based drug delivery systems in oncology: From bench to presentations and short presentations. bedside We look very much forward to welcome you in Biele- Pirjo Laakkonen Biomedicum Helsinki, FI feld! Peptide-based tumor targeting Maxime Lampilas Sanofi, Vitry sur Seine, FR The conference committee Process development of SPDB/DM4 conjugates www.magicbullet.de www.magicbullet.de www.magicbullet.de.
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