Course Catalog 2019-2020
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Fas Ligand, Bcl-2, Granulocyte Colony-Stimulating Factor, and P38
Fas Ligand, Bcl-2, Granulocyte Colony-Stimulating Factor, and p38 Mitogen-activated Protein Kinase: Regulators of Distinct Cell Death and Survival Pathways in Granulocytes By Andreas Villunger,* Lorraine A. O’Reilly,* Nils Holler,‡ Jerry Adams,* and Andreas Strasser* From *The Walter and Eliza Hall Institute, Melbourne, Victoria 3050, Australia; and the ‡Institute of Biochemistry, University of Lausanne, Epalinges CH-1066, Switzerland Abstract The short life span of granulocytes, which limits many inflammatory responses, is thought to be influenced by the Bcl-2 protein family, death receptors such as CD95 (Fas/APO-1), stress-acti- vated protein kinases such as p38 mitogen-activated protein kinase (MAPK), and proinflamma- tory cytokines like granulocyte colony-stimulating factor (G-CSF). To clarify the roles of these various regulators in granulocyte survival, we have investigated the spontaneous apoptosis of granulocytes in culture and that induced by Fas ligand or chemotherapeutic drugs, using cells from normal, CD95-deficient lpr, or vav-bcl-2 transgenic mice. CD95-induced apoptosis, which required receptor aggregation by recombinant Fas ligand or the membrane-bound ligand, was unaffected by G-CSF treatment or Bcl-2 overexpression. Conversely, spontaneous and drug-induced apoptosis occurred normally in lpr granulocytes but were suppressed by G-CSF treatment or Bcl-2 overexpression. Although activation of p38 MAPK has been implicated in granulocyte death, their apoptosis actually was markedly accelerated by specific inhibitors of this kinase. These results suggest that G-CSF promotes granulocyte survival largely through the Bcl-2–controlled pathway, whereas CD95 regulates a distinct pathway to apoptosis that is not required for either their spontaneous or drug-induced death. -
To Professor Suzanne Cory AC
Citation for the Award of the Doctor of Laws (Honoris Causa) to Professor Suzanne Cory AC When Suzanne Cory graduated from the Science Faculty at the University of Melbourne molecular biology was in its infancy. In her enthusiasm for this new science she pursued a PhD in Cambridge at the Medical Research Council’s famed Laboratory of Molecular Biology. Immersed in a culture of discovery, her pioneering PhD studies determined the sequence of a transfer RNA, utilising new technology developed by Fred Sanger, one of the three Nobel Laureates in the institute. After three years’ post‐doctoral work at the University of Geneva, Suzanne Cory returned to Australia with her husband, Jerry Adams, to the Walter and Eliza Hall Institute of Medical Research where they helped to introduce gene‐cloning technology to Australia. Since then, her long association with the Institute, including thirteen years as Director, and with the University of Melbourne, has been instrumental in building the international reputation of both institutions and the strength of the Parkville biomedical research network. Suzanne Cory has made major contributions to advancing the science of immunology, cancer and genetics, in a lifelong dynamic research partnership with Adams. Her work is published widely and cited frequently. The positions held by the many PhD candidates and Post‐Doctoral Fellows she has supervised demonstrate her intergenerational influence in developing scientific leaders for the future. The list of accolades and awards Suzanne Cory has received in recognition of her contributions to science is long and distinguished. She was elected a Fellow of the Australian Academy of Science in 1986 and since has been elected to numerous sister organisations across the globe. -
Huzzah to the Double Helix! It's International DNA Day | Lifehacker
Huzzah To The Double Helix! It’s International DNA Day | L... http://www.lifehacker.com.au/2013/04/huzzah-to-the-double-h... Business Insider Gizmodo Kotaku Lifehacker PopSugar BellaSugar FabSugar ShopStyle Log In Register Life Work IT Pro RECENTLY ON KOTAKU RECENTLY ON KOTAKU Robin Has A Point In These Hilarious Conference Or Not, We’ll Cherish Superhero Texts These E3 Nintendo Memes Forever HOME Huzzah To The Double Helix! It’s International DNA Day CHRIS JAGER YESTERDAY 9:30 AM Share 5858 Discuss 22 Today is International DNA Day, which this year commemorates 60 years since the scientific paper A Structure for Deoxyribose Nucleic Acid was first published. Here’s what some of Australia’s leading scientists SUBSCRIBE have to say about the importance of the discovery… CONTACT DNA picture from Shutterstock Sixty years ago to the day, James Watson and Francis Crick published a revolutionary paper on the Like Lifehacker Australia 5,616 Followers structure of Deoxyribonucleic acid; the molecular key to all living things otherwise known as DNA. A Follow Lifehacker Australia 11,734 Followers century after Gregor Mendel first began messing about with peas, the final piece of the genetic puzzle had been slotted into place. Subscribe to all stories 15,269 Followers To mark this historic occasion, several Australian scientists have released statements in which they Australian stories 1,859 Followers basically wax lyrical about the wonders of DNA — what better way to start your morning? (And if you’re wondering what the Lifehacker angle is, the answer is quite simple: when someone smarter than you has something to say, it’s usually worth listening!) REGULARS LIFE Professor Suzanne Cory, President of the Australian Academy of Science: Sell Your Stuff And Get Some Extra Cash This Weekend The discovery of the structure of DNA by James Watson and Francis Crick was an epic moment in the history of science. -
Member Colleges
SAGE Scholars, Inc. 21 South 12th St., 9th Floor Philadelphia, PA 19107 voice 215-564-9930 fax 215-564-9934 [email protected] Member Colleges Alabama Illinois Kentucky (continued) Missouri (continued) Birmingham Southern College Benedictine University Georgetown College Lindenwood University Faulkner Univeristy Bradley University Lindsey Wilson College Missouri Baptist University Huntingdon College Concordia University Chicago University of the Cumberlands Missouri Valley College Spring Hill College DePaul University Louisiana William Jewell College Arizona Dominican University Loyola University New Orleans Montana Benedictine University at Mesa Elmhurst College Maine Carroll College Embry-Riddle Aeronautical Univ. Greenville College College of the Atlantic Rocky Mountain College Prescott College Illinois Institute of Technology Thomas College Nebraska Arkansas Judson University Unity College Creighton University Harding University Lake Forest College Maryland Hastings College John Brown University Lewis University Hood College Midland Lutheran College Lyon College Lincoln College Lancaster Bible College (Lanham) Nebraska Wesleyan University Ouachita Baptist University McKendree University Maryland Institute College of Art York College University of the Ozarks Millikin University Mount St. Mary’s University Nevada North Central College California Massachusetts Sierra Nevada College Olivet Nazarene University Alliant International University Anna Maria College New Hampshire Quincy University California College of the Arts Clark University -
A Null C-Myc Mutation Causes Lethality Before 10.5 Days of Gestation in Homozygotes and Reduced Fertility in Heterozygous Female Mice
Downloaded from genesdev.cshlp.org on October 6, 2021 - Published by Cold Spring Harbor Laboratory Press A null c-myc mutation causes lethality before 10.5 days of gestation in homozygotes and reduced fertility in heterozygous female mice Ann C. Davis, 1 Marie Wims, 1 Gerald D. Spotts, 2 Stephen R. Hann, 2 and Allan Bradley 1 tlnstitute for Molecular Genetics, Baylor College of Medicine, Houston, Texas 77030 USA; ~Department of Cell Biology, Vanderbilt University, School of Medicine, Nashville, Tennessee 37232-2175 USA To directly assess c-myc function in cellular proliferation, differentiation, and embryogenesis, we have used homologous recombination in embryonic stem cells to generate both heterozygous and homozygous c-myc mutant ES cell lines. The mutation is a null allele at the protein level. Mouse chimeras from seven heterozygous cell lines transmitted the mutant allele to their offspring. The analysis of embryos from two clones has shown that the mutation is lethal in homozygotes between 9.5 and 10.5 days of gestation. The embryos are generally smaller and retarded in development compared with their littermates. Pathologic abnormalities include the heart, pericardium, neural tube, and delay or failure in turning of the embryo. Heterozygous females have reduced fertility owing to embryonic resorption before 9.5 days of gestation in 14% of implanted embryos, c-Myc protein is necessary for embryonic survival beyond 10.5 days of gestation; however, it appears to be dispensable for cell division both in ES cell lines and in the the embryo before that time. [Key Words: c-myc; gene targeting; null mutation~ embryonic lethal] Received November 25, 1992; revised version accepted January 25, 1993. -
2020 Bullitteast High School Senior Awards Ceremony
2020 Bullitt East High School Senior Awards Ceremony Work Ethic Certification Seniors had to submit an application, have 2 or less unexcused absences, zero behavior incidents, no grades lower than a C on a report card, and be involved in 2 or more school sponsored or approved activities to meet certification requirements. ● Michael Allen ● Sawyer Kelty ● Olivia Smith ● Macie Brown ● Valerie King ● Carsyn Spears ● ● Hailey Stivers ● Jacob Bullock Shelby Knieriem ● Emily Moats ● Lexi Taylor ● Russell Dennis ● Montrell Page ● ● Reece Tomlinson Andrea Foley ● Logan Parrish ● Cameron Waddle ● Kennedy Griffin ● Connor Phelps ● Elizabeth Woods ● Molly Hill ● Caroline Scott ● Evan Wright ● Nathaniel ● Brianna Shannon Hoagland-Richardson Tara Alexander Royal Holloway, University of London ● Future Leaders 2020 Bullitt East Senior Scholarships Natalie Allen Carson Armstrong University of Louisville University of Louisville ● Spalding University ● Academic University of Louisville Trustees’ 2020 Bullitt East Senior Scholarships Olivia Armstrong Catie Bacon University of Louisville University of Pikeville ● University of ● Louisville Henry University of Vogt Scholarship Pikeville Academic ● ● Chick-fil-A University of Remarkable Futures Pikeville Athletic (soccer) ● Bullitt County Soil & Conservation ● Campbellsville University Academic 2020 Bullitt East Senior Scholarships Meredith Bass Samuel Brangers University of Kentucky University of Kentucky ● University of ● Kentucky Provost BEHS Athletic ● BEHS National Honor Booster Club Society ● Western Kentucky -
Education Job Search Guide
EDUCATION JOB SEARCH GUIDE Jennifer Pickerell, M.A. Katie Schuetz, M.A. Director Assistant Director 618.537.6806 618.537.6805 [email protected] [email protected] www.mckendree.edu/careerservices McKendree University Career Services Follow us at @McKCareers McKendree University Career Services TABLE OF CONTENTS Beginning a Job Search in Education Page 1 Networking Page 2 Designing a Résumé Page 3 Transferable Skills Checklist Page 4 Basic Contents of an Education Résumé Page 6 Alternative Headings Page 7 What Makes Me Different Page 8 Action Verbs Page 9 Example Résumés Page 11 Résumé Checklist Page 28 Reference Page Page 29 Cover Letters Page 30 Internet Job Posting Resources Page 34 REAP Introduction Page 35 Interviews Page 36 Preparing for an Interview Page 37 Common Interview Questions Page 38 Behavior-Based Questions Page 41 Illegal Interview Questions Page 43 Career Fair Tips Page 44 Interview Attire Page 46 Thank You Letters Page 47 Job Acceptance Letters Page 48 Assistance from Career Services Page 49 BEGINNING A JOB SEARCH IN EDUCATION 1) Prepare and tailor all materials needed to apply for each position: Prepare your cover letter, résumé, references, 30-second commercial, interview skills, interview attire, questions to ask the employer, and thank you letters. Many schools require an application with a writing section in addition to your résumé and other credentials. 2) Begin your search before the last semester of your program. Districts hire at different times. Many start to interview as early as January for the fall, or during the fall and winter months for January start dates. Maternity leave, medical leave, retirement, non- renewed contracts, and other circumstances impact vacancies. -
Graduate School
Make Your Mark Make Your 2012 / 2013 graduate catalog GRADUATE SCHOOL 2012 / 2013 graduate catalog 701 College Road Lebanon, IL 62254 618-537-4481 www.mckendree.edu Courses of Study i GRADUATE SCHOOL 2012 / 2013 graduate catalog 701 College Road Lebanon, IL 62254 618-537-4481 1-800-BEARCAT www.mckendree.edu Make Your Mark ii Mc.KENDREE UNIVERSITY — 2012/2013 Accreditations Approvals & Associated Colleges of Illinois (ACI) Higher Learning Licenses Commission of the North Illinois Board Association for Black Central Association of of Higher Education Culture Centers (ABCC) Colleges and Schools 431 East Adams Association for the 230 South LaSalle St. 2nd Floor Assessment of Learning Suite 7-500 Springfield, IL 62701-1404 in Higher Education Chicago, IL 60604-1413 217-782-2551 (AALHE) 800-621-7440 Illinois Department Association of American Commission on Collegiate of Veterans’ Affairs Colleges and Universities Nursing Education (CCNE) 833 South Spring Street (AAC&U) One Dupont Circle NW P.O. Box 19432 Council for the Advance- Suite 530 Springfield, IL 62794-9432 ment and Support of Washington, DC 20036 217-782-6641 Education (CASE) 202-887-6791 Illinois State Board Council of Independent International Assembly of Education Colleges (CIC) for Collegiate Business 100 N. 1st Street Education (IACBE) Springfield, IL 62777 Federation of Independent P.O. Box 3960 866-262-6663 Illinois Colleges and Universities (FIICU) Olathe, KS 66063 Kentucky Approving Agency 913-631-3009 for Veterans’ Education Illinois Campus Compact National Council for 300 -
2017-2018 Undergraduate Catalog
TE CATALOG TE A U MAKE YOUR MARK MAKE YOUR UNDERGRAD 2017 / 2018 2017/2018 UNDERGRADUATE CATALOG 701 College Road Lebanon, IL 62254 618-537-4481 www.mckendree.edu i Admissions 2017 / 2018 UNDERGRADUATE CATALOG ON THE COVER: 701 College Road MCKENDREE UNIVERSITY Lebanon, IL 62254 GONFALON 618-537-4481 1-800-BEARCAT Gonfalons originated in medieval Italy as a signal of state www.mckendree.edu or office, but has been adopted by universities around the world as insignias of schools or colleges. Our gonfalons, or academic banners, designate the University, the College of Arts and Sciences, the School of Business, the School of Education, and the School of Nursing and Health Professions. ii McKendree University 2017/2018 UndergraduateT Cataloghe University Mission ..................... 5 Admission .........................................13 Student Services ..............................23 Academic Policies ............................25 General Education Program ..........51 ACCREDITATIONS MEMBERSHIPS Courses of Study Higher Learning Commission American Association College of Arts and Sciences ....59 230 South LaSalle St. of Colleges for Teacher Suite 7-500 Education (AACTE) Art • Art History • Art Education • Chicago, IL 60604-1413 Biochemistry • Biology • Chemistry American Association 800-621-7440 • Computing (Computer Science, of Colleges of Nursing (AACN) Computer Information Systems, Commission on Accreditation American Council on of Athletic Training Education Computational Science, and Education (ACE) (CAATE) Information Technology) -
Information Pertinent to COVID-19 Responses/Actions for the Following Illinois Colleges and Universities Is Linked Below
Information pertinent to COVID-19 responses/actions for the following Illinois colleges and universities is linked below. Illinois Public Universities Illinois Community Colleges Chicago State University Black Hawk College Eastern Illinois University Carl Sandburg College Governors State University City Colleges of Chicago Illinois State University College of DuPage Northeastern Illinois University College of Lake County Northern Illinois University Danville Area Community College Southern Illinois University Carbondale Elgin Community College Southern Illinois University Edwardsville Harper College University of Illinois at Chicago Heartland Community College University of Illinois at Springfield Highland Community College University of Illinois at Urbana-Champaign Illinois Central College University of Illinois System Illinois Eastern Community Colleges Western Illinois University Illinois Valley Community College John A. Logan College John Wood Community College Joliet Junior College Kankakee Community College Kaskaskia College Kishwaukee College Lake Land College Lewis & Clark Community College Lincoln Land Community College McHenry County College Morton College Oakton Community College Parkland College Prairie State College Rend Lake College Richland Community College Rock Valley College Sauk Valley Community College Shawnee Community College South Suburban College Southeastern Illinois College Southwestern Illinois College Spoon River College Triton College Waubonsee Community College Moraine Valley Community College Created on -
2010-2011 Annual Report
Annual Report 2010-2011 Mastery of disease through discovery | www.wehi.edu.au Contents 1 About the institute 3 Director’s and Chairman’s report 5 Discovery 8 Cancer and Haematology 10 Stem Cells and Cancer 12 Molecular Genetics of Cancer 14 Chemical Biology 16 Molecular Medicine 18 Structural Biology 20 Bioinformatics 22 Infection and Immunity 24 Immunology The Walter and Eliza Hall Institute 26 Autoimmunity and Transplantation of Medical Research 28 Cell Signalling and Cell Death 1G Royal Parade 30 Inflammation Parkville Victoria 3052 Australia Telephone: (+61 3) 9345 2555 32 Molecular Immunology Facsimile: (+61 3) 9347 0852 34 Publications WEHI Biotechnology Centre 36 Awards 4 Research Avenue 37 Translation La Trobe R&D Park Bundoora Victoria 3086 Australia Translating our research 38 Telephone: (+61 3) 9345 2200 40 Developing our research Facsimile: (+61 3) 9345 2211 42 Patents www.wehi.edu.au www.facebook.com/WEHIresearch 43 Education www.twitter.com/WEHI_research 46 2010-11 graduates ABN 12 004 251 423 47 Seminars Acknowledgements 48 Institute awards Produced by the institute’s Community Relations department 49 Engagement Managing editor: Penny Fannin Editor: Liz Williams 51 Strategic partners Writers: Liz Williams, Vanessa Solomon and Julie Tester 52 Scientific and medical community Design and production: Simon Taplin Photography: Czesia Markiewicz and Cameron Wells 54 Public engagement 57 Engagement with schools Cover image 58 Donor and bequestor engagement Art in Science finalist 2010 Vessel webs 59 Sustainability Dr Leigh Coultas, Cancer and Haematology division 60 The Board This image shows the delicate intricacy in the developing eye of a transient population of web-like blood vessels. -
Expression of the Other in T Cells Bim and Bcl-2 Mutually Affect
Bim and Bcl-2 Mutually Affect the Expression of the Other in T Cells Trine N. Jorgensen, Amy McKee, Michael Wang, Ella Kushnir, Janice White, Yosef Refaeli, John W. Kappler and This information is current as Philippa Marrack of September 25, 2021. J Immunol 2007; 179:3417-3424; ; doi: 10.4049/jimmunol.179.6.3417 http://www.jimmunol.org/content/179/6/3417 Downloaded from References This article cites 54 articles, 22 of which you can access for free at: http://www.jimmunol.org/content/179/6/3417.full#ref-list-1 http://www.jimmunol.org/ Why The JI? Submit online. • Rapid Reviews! 30 days* from submission to initial decision • No Triage! Every submission reviewed by practicing scientists • Fast Publication! 4 weeks from acceptance to publication by guest on September 25, 2021 *average Subscription Information about subscribing to The Journal of Immunology is online at: http://jimmunol.org/subscription Permissions Submit copyright permission requests at: http://www.aai.org/About/Publications/JI/copyright.html Email Alerts Receive free email-alerts when new articles cite this article. Sign up at: http://jimmunol.org/alerts The Journal of Immunology is published twice each month by The American Association of Immunologists, Inc., 1451 Rockville Pike, Suite 650, Rockville, MD 20852 Copyright © 2007 by The American Association of Immunologists All rights reserved. Print ISSN: 0022-1767 Online ISSN: 1550-6606. The Journal of Immunology Bim and Bcl-2 Mutually Affect the Expression of the Other in T Cells1 Trine N. Jorgensen,2* Amy McKee,2*ʈ Michael Wang,2† Ella Kushnir,*ʈ Janice White,*ʈ Yosef Refaeli,** John W.