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Appendix G ECOTOX Literature

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Appendix G ECOTOX Literature Accepted ECOTOX Data Table……………………………………………………………...2 Explanation of OPP Acceptability Criteria and Rejection Codes for ECOTOX Data….44 Papers Acceptable for ECOTOX and OPP………………………………………………...45 Papers Acceptable for ECOTOX but not OPP…………………………………………….76 Papers Excluded…………………………………………………………………………….187 Open Literature Review Summaries………………………………………………………313 G-1 APPENDIX G: Accepted ECOTOX Data Table The code list for ECOTOX can be found at: http://cfpub.epa.gov/ecotox/blackbox/help/codelist.pdf Conc Conc Value2 Conc Effect Dur Unit Dur Dur Unit Value1 Preferre Units Chemical Name Genus Species Common Name Group Effect Meas Endpt1 Endpt2 Orig Preferred Preferred Preferred d Preferred % Purity Ref # 2,4-D Rattus norvegicus Norway rat ACC ACC RSDE NOAEL d 30 d 100 ppm 100 93410 2,4-D Rattus norvegicus Norway rat ACC ACC RSDE NOAEL d 30 d 50 ppm 100 93410 2,4-D dimethylamine salt Rattus norvegicus Norway rat ACC ACC GACC LOAEL h 4.17E-02 d 200 ppm 100 93633 2,4-D Tetrahymena pyriformis Ciliate BEH AVO STIM EC50 h 4.17E-02 d 158.3 mg/L 100 60864 2,4-D Myriophyllum sibiricum Water milfoil BCM BCM CHLA LOAEL d 14 d 1.47 mg/L 100 74985 2,4-D Myriophyllum sibiricum Water milfoil BCM BCM CHLA LOAEL d 14 d 1.47 mg/L 100 74985 2,4-D Myriophyllum sibiricum Water milfoil BCM BCM CHLA NOEC LOEC d 14 d 0.0543 0.163 mg/L 100 74985 2,4-D Myriophyllum sibiricum Water milfoil BCM BCM CHLA IC25 d 14 d 0.1662 mg/L 100 74985 2,4-D Myriophyllum sibiricum Water milfoil BCM BCM CHLA IC50 d 14 d 0.3137 mg/L 100 74985 2,4-D Myriophyllum sibiricum Water milfoil BCM BCM CHLB NOEC LOEC d 14 d 0.0543 0.163 mg/L 100 74985 2,4-D Myriophyllum sibiricum Water milfoil BCM BCM CHLB IC25 d 14 d 0.1523 mg/L 100 74985 2,4-D Myriophyllum sibiricum Water milfoil BCM BCM CHLB IC50 d 14 d 0.2537 mg/L 100 74985 2,4-D Myriophyllum sibiricum Water milfoil BCM BCM CARC NOEC LOEC d 14 d 0.0543 0.163 mg/L 100 74985 2,4-D Myriophyllum sibiricum Water milfoil BCM BCM CARC IC25 d 14 d 0.1461 mg/L 100 74985 2,4-D Myriophyllum sibiricum Water milfoil BCM BCM CARC IC50 d 14 d 0.3085 mg/L 100 74985 2,4-D Myriophyllum sibiricum Water milfoil BCM BCM CHLA NOEC LOEC d 14 d 0.0181 0.0543 mg/L 100 74985 2,4-D Myriophyllum sibiricum Water milfoil BCM BCM CHLA IC25 d 14 d 0.0426 mg/L 100 74985 2,4-D Myriophyllum sibiricum Water milfoil BCM BCM CHLA IC50 d 14 d 0.1238 mg/L 100 74985 2,4-D Myriophyllum sibiricum Water milfoil BCM BCM CHLB NOEC LOEC d 14 d 0.0543 0.163 mg/L 100 74985 2,4-D Myriophyllum sibiricum Water milfoil BCM BCM CHLB IC25 d 14 d 0.0672 mg/L 100 74985 2,4-D Myriophyllum sibiricum Water milfoil BCM BCM CHLB IC50 d 14 d 0.1413 mg/L 100 74985 2,4-D Myriophyllum sibiricum Water milfoil BCM BCM CARC NOEC LOEC d 14 d 0.0181 0.0543 mg/L 100 74985 2,4-D Myriophyllum sibiricum Water milfoil BCM BCM CARC IC25 d 14 d 0.0345 mg/L 100 74985 2,4-D Myriophyllum sibiricum Water milfoil BCM BCM CARC IC50 d 14 d 0.1096 mg/L 100 74985 2,4-D Fundulus heteroclitus Mummichog BCM BCM PRTL LOAEL d 14 d 0.01 mg/L 100 93400 2,4-D Scenedesmus quadricauda Green algae BCM BCM CHLA NOAEL LOAEL stg NA stg 0.98 9.8 mg/L 49 55720 Mediterranean 2,4-D Mytilus galloprovincialis mussel BCM BCM CAMP LOAEL d 15 d 0.03 mg/L 100 93394 2,4-D Salvelinus fontinalis Brook trout BCM BCM PLSC LOAEL d 7 d 5 mg/L 97 to 72745 ae 2,4-D Canis familiaris Domestic dog BCM BCM NCON NOAEL LOEL wk 91 d 1 3.75 mg/kg/d 96.7 48144 ae 2,4-D Canis familiaris Domestic dog BCM BCM CRTN NOAEL LOEL wk 91 d 0.5 1 mg/kg/d 96.7 48144 2,4-D Canis familiaris Domestic dog BCM BCM CREA NOAEL LOAEL wk 28 d 1 5 ppm 96.7 48144 2,4-D Canis familiaris Domestic dog BCM BCM CREA LOAEL wk 28 d 1 ppm 96.7 48144 2,4-D Rattus norvegicus Norway rat BCM BCM PRCO LOAEL d 90 d 100 ppm 100 90486 2,4-D Eisenia fetida Earthworm BCM BCM SERP NOAEL LOAEL h 2 d 3.5 18 ug/cm2 100 40121 2,4-D Mus musculus House mouse BCM BCM ANTO NOAEL LOAEL d 9 d 0.1 100 ppm 100 93603 2,4-D Mus musculus House mouse BCM BCM ANTO NOAEL LOAEL d 9 d 0.1 100 ppm 100 93603 2,4-D Rattus norvegicus Norway rat BCM BCM 5HAA LOAEL h 0.1458333 d 47.5 mg/kg >95 93598 2,4-D Rattus norvegicus Norway rat BCM BCM 5HAA LOAEL h 0.1458333 d 47.5 mg/kg >95 93598 2,4-D Rattus norvegicus Norway rat BCM BCM GNGL LOAEL d 18 d 100 mg/kg 100 93629 2,4-D Rattus norvegicus Norway rat BCM BCM GNGL LOAEL d 18 d 70 mg/kg 100 93629 mg/kg 2,4-D Rattus norvegicus Norway rat BCM BCM FECO LOAEL d 16 d 70 bdwt 100 85545 G-2 Conc Conc Value2 Conc Effect Dur Unit Dur Dur Unit Value1 Preferre Units Chemical Name Genus Species Common Name Group Effect Meas Endpt1 Endpt2 Orig Preferred Preferred Preferred d Preferred % Purity Ref # mg/kg 2,4-D Rattus norvegicus Norway rat BCM BCM FECO LOAEL d 16 d 70 bdwt 100 85545 2,4-D Plankton Plankton NR BCM BCM GBCM EC50 h 0.125 d 33 mg/L 100 13724 2,4-D Plankton Plankton NR BCM BCM GBCM EC50 h 0.125 d 33 mg/L 100 13724 2,4-D Plankton Plankton NR BCM BCM GBCM EC50 h 0.125 d 33 mg/L 100 13724 2,4-D Chlorella pyrenoidosa Green algae BCM BCM CHLO LOEC h 3 d 50 mg/L 100 15189 2,4-D Chlorella pyrenoidosa Green algae BCM BCM CHLO NOEC h 3 d 5 mg/L 100 15189 2,4-D Daphnia magna Water flea BCM BCM GBCM NOEC d 21 d 32 mg/L 100 16782 2,4-D Daphnia magna Water flea BCM BCM GBCM LOEC d 21 d 56 mg/L 100 16782 2,4-D Rattus norvegicus Norway rat BCM BCM TRIG NOAEL mo 180 d 0.05 % 100 94239 2,4-D Mus musculus House mouse BCM BCM MCPR LOAEL d 4 d 100 ppm 100 93403 mg/kg 2,4-D Rattus norvegicus Norway rat BCM BCM CHOL NOAEL wk 14 d 150 TO 200 bdwt 100 93402 mg/kg 2,4-D Rattus norvegicus Norway rat BCM BCM PHST LOAEL d 14 d 200 bdwt 100 93542 2,4-D Rattus norvegicus Norway rat BCM BCM GD1A LOAEL d 18 d 70 mg/kg 100 93434 2,4-D Rattus norvegicus Norway rat BCM BCM GGT1 LOAEL d 13 d 70 mg/kg 100 93434 2,4-D Rattus norvegicus Norway rat BCM BCM HVLA NOAEL d 96 d 70 ppm 100 93509 2,4-D Rattus norvegicus Norway rat BCM BCM HVLA LOAEL d 96 d 70 ppm 100 93509 2,4-D Rattus norvegicus Norway rat BCM BCM FFTA LOAEL d 15 d 14.7 ppm 98 93522 2,4-D dimethylamine salt Cyprinus carpio common carp BCM BCM MLDH NOAEL h 4 d 87 mg/L 100 73377 2,4-D dimethylamine salt Tilapia nilotica Nile tilapia BCM BCM MLDH NOAEL h 4 d 87 mg/L 100 73377 2,4-D dimethylamine salt Cyprinus carpio common carp BCM BCM MLDH NOAEL h 4 d 87 mg/L 100 93395 2,4-D dimethylamine salt Tilapia nilotica Nile tilapia BCM BCM MLDH NOAEL h 4 d 27 mg/L 100 60050 2,4-D dimethylamine salt Eichhornia crassipes Water-hyacinth BCM BCM PCON LOAEL d <=17 d 0.25 kg/ha 50 71785 2,4-D dimethylamine mg/kg salt Bos taurus Domesticated cattle BCM BCM HMCT NOAEL h 1 d 600 bdwt 100 93405 2,4-D dimethylamine ae salt Canis familiaris Domestic dog BCM BCM NCON LOEL wk 91 d 1 mg/kg/d 66.7 48144 2,4-D dimethylamine ae salt Canis familiaris Domestic dog BCM BCM CREA LOEL wk 91 d 1 mg/kg/d 66.7 48144 2,4-D dimethylamine mg/kg salt Rattus norvegicus Norway rat BCM BCM GLUC LOAEL h 0.2083333 d 600 bdwt 100 40139 2,4-D dimethylamine salt Salvinia natans Floating moss BCM BCM CHLO EC50 wk 28 d 0.3 mg/L 100 13738 2,4-D dimethylamine salt Salvinia natans Floating moss BCM BCM CHLO EC50 wk 28 d 0.3 mg/L 100 13738 2,4-D dimethylamine AI mg/kg salt Rattus norvegicus Norway rat BCM BCM GLUC LOAEL h 0.2083333 d 600 bdwt/d 100 40128 2,4-D dimethylamine AI mg/kg salt Rattus norvegicus Norway rat BCM BCM ALBM LOAEL d 30 d 200 bdwt/d 100 40128 2,4-D dimethylamine AI mg/kg salt Rattus norvegicus Norway rat BCM BCM GLUC LOAEL d 180 d 200 bdwt/d 100 40128 G-3 Conc Conc Value2 Conc Effect Dur Unit Dur Dur Unit Value1 Preferre Units Chemical Name Genus Species Common Name Group Effect Meas Endpt1 Endpt2 Orig Preferred Preferred Preferred d Preferred % Purity Ref # 2,4-D dimethylamine mg/kg salt Bos taurus Domesticated cattle BCM BCM UREA LOAEL h 0.1666667 d 100 bdwt 100 40111 2,4-D dimethylamine mg/kg salt Gallus domesticus Domestic Chicken BCM BCM URIC NOAEL LOAEL h 8.33E-02 d 100 300 bdwt 100 87186 2,4-D dimethylamine Rainbow salt Oncorhynchus mykiss trout,donaldson trout BCM BCM VITE LOAEL d 7 d 1.64 mg/L 100 80643 2,4-D dimethylamine Rainbow salt Oncorhynchus mykiss trout,donaldson trout BCM BCM VITE LOEC NOEC d 7 d 0.164 0.0164 mg/L 100 80643 2,4-D dimethylamine mg/kg salt Rattus norvegicus Norway rat BCM BCM PHST NOAEL wk 14 d 200 bdwt 100 72915 2,4-D dimethylamine salt Gallus domesticus Domestic Chicken BCM BCM PRCO LOAEL d 5 d 0.72 ul/kg 40 91304 2,4-D sodium salt Rattus norvegicus Norway rat BCM BCM 5HAA LOAEL h 4.17E-02 d 200 mg/kg 100 93387 2,4-D sodium salt Rattus norvegicus Norway rat BCM BCM 5HAA NOAEL LOAEL h 8.33E-02 d 10 30 mg/kg 100 93387 2,4-D Rattus norvegicus Norway rat BEH BEH NMVM NOAEL d ~35 d 50 TO 70 ppm 100 93507 2,4-D Rattus norvegicus Norway rat BEH BEH NMVM LOAEL d ~35 d 50 TO 70 ppm 100 93507 2,4-D Rattus norvegicus Norway rat BEH BEH NMVM LOAEL d ~35 d 50 TO 70 ppm 100 93507 2,4-D Rattus norvegicus Norway rat BEH BEH NMVM LOAEL d ~35 d 50 TO 70 ppm 100 93507 2,4-D Rattus norvegicus Norway rat BEH BEH RRSP LOAEL d 4 d 100 mg/kg 100 93629 2,4-D Rattus norvegicus Norway rat BEH BEH GBHV LOAEL d 11 d 70 mg/kg 100 93629 2,4-D Rattus norvegicus Norway rat BEH BEH VMVT LOAEL d 18 d 100 mg/kg 100 93629 2,4-D Rattus norvegicus Norway rat BEH BEH VMVT LOAEL d 18 d 70 mg/kg 100 93629 Dungeness or edible 2,4-D Cancer magister crab BEH BEH EQUL EC50 h 4 d 100 mg/L 98 6793 2,4-D Rattus norvegicus Norway rat BEH BEH NGRX LOAEL d 7 d 70 mg/kg 100 93507 2,4-D Rattus norvegicus Norway rat BEH BEH ACTV LOAEL h 0.25 d 100 ug 100 93508 2,4-D Rattus norvegicus Norway rat BEH BEH ACTV LOAEL h 0.25 d 100 ug 100 93508 2,4-D Rattus norvegicus Norway rat
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