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Alumni Directory 1992 ‐ 2021

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Alumni Directory 1992 ‐ 2021 Alumni Directory 1992 ‐ 2021 Updated, 4/2021 The Richard and Susan Smith Family Foundation is committed to effecting permanent positive change in the lives of the residents of Greater Boston, particularly individuals and families in economically disadvantaged communities. Today, three generations of the Smith family oversee the Foundation, stewarding approximately $15 million annually in grants aimed at promoting greater health, educational attainment, and economic mobility. In the area of health, the Foundation supports the advancement of biomedical research and the expansion of access to high‐quality health care at safety net institutions serving low‐income individuals and communities of Greater Boston. In 1991, the Smith Family Foundation contracted with The Medical Foundation at Health Resources in Action to create a grantmaking program that would identify and support promising junior faculty to find breakthroughs in such areas as AIDS/HIV, cancer, heart disease, diabetes or neuroscience. Since 2008, the Award has broadened to support newly independent faculty engaged in basic biomedical science as well as physics, chemistry and engineering with a focus on biomedicine. The Awards are currently in the amount of $300,000 over three years. Over the past 30 years, the Smith Family Awards Program for Excellence in Biomedical Research has helped launch the careers of 181 outstanding scientists with support totaling $38.3 million. The following is a listing of all Award Recipients in alphabetical order with current contact information as well as the title of the funded research project. The Smith Family is extraordinarily proud of the accomplishments of its Awardees and is honored to provide the critical support for their newly established research programs. 2 Cristina Aguayo‐Mazzucato, M.D., Ph.D. Jennifer Benanti, Ph.D. (2021 Award Recipient) (2011 Award Recipient) Targeting Beta‐Cell Senescence in Diabetes Mapping the Proteolytic Regulatory Network Joslin Diabetes Center that Controls Cell Division cristina.aguayo‐ University of Massachusetts Medical School [email protected] [email protected] Judith Agudo, Ph.D. Leslie J. Berg, Ph.D. (2019 Award Recipient) (1993 Award Recipient) Novel platform to increase dendritic cell Analysis of the Tsk tyrosine Kinase in function and antigen‐specific T cell responses Transgenic Mice to cancer University of Massachusetts Medical School Dana‐Farber Cancer Institute [email protected] [email protected] Sudha Biddinger, M.D., Ph.D. Mark L. Andermann, Ph.D. (2010 Award Recipient) (2012 Award Recipient) Regulation of the LDLR by Insulin and Cortical Networks Guiding Hunger‐Dependent Diabetes Attention to Food Cues Boston Children's Hospital Beth Israel Deaconess Medical Center [email protected] [email protected] Jonathan S. Bogan, M.D. Zolt P. Arany, M.D., Ph.D. (2000 Award Recipient) (2008 Award Recipient) Role of ARF Proteins in GLUT4 Trafficking Peroxisome Proliferator‐Activated Receptor Yale School of Medicine Gamma 1alpha (PGC‐1alpha) and Cardiac [email protected] Angiogenesis University of Pennsylvania Laurie A. Boyer, Ph.D. [email protected] (2009 Award Recipient) Non‐coding RNA as a Regulator of Cell Fate Scott A. Armstrong, M.D., Ph.D. through Functional Interaction with Polycomb (2004 Award Recipient) Group Proteins Multi‐step Pathogenesis of MLL‐rearranged Massachusetts Institute of Technology Leukemias [email protected] Memorial Sloan‐Kettering Cancer Center [email protected] James E. Bradner, M.D. (2010 Award Recipient) Emily Patricia Balskus, Ph.D. Chemical Inhibition of Bromodomains in (2011 Award Recipient) Cancer Understanding and Preventing the Production Novartis Institutes of BioMedical Resaerch of Disease‐Associated Metabolites by the [email protected] Human Gut Microbiota Harvard University [email protected] 3 David K Breslow, Ph.D. Abhishek Chatterjee, Ph.D. (2018 Award Recipient) (2013 Award Recipient) Deconstructing the Cellular Antenna: Primary A Chemical Toolset to Investigate and Cilium Disassembly and Control of Cell Engineer Viral Infection Growth Boston College Yale University [email protected] [email protected] Iain M. Cheeseman, Ph.D. Alan Brown, Ph.D. (2007 Award Recipient) (2018 Award Recipient) Proteomic and Functional Dissection of the Structural Basis of Intraflagellar Transport Human Kinetochore Harvard Medical School Whitehead Institute for Biomedical Research [email protected] [email protected] Jessica A Cardin, Ph.D. Jianzhu Chen, Ph.D. (2012 Award Recipient) (1995 Award Recipient) GABAergic Contributions to Neural and Molecular Analysis of Memory B Cell Cognitive Deficits in a Genetic Model of Differentiation Schizophrenia. Massachusetts Institute of Technology Yale University [email protected] [email protected] Jerry Lu Chen, Ph.D. William A. Carlezon, Ph.D. (2016 Award Recipient) (1999 Award Recipient) Circuit Mechanisms for Long‐Range Neural Substrates of Aversion to Addictive Communication in the Neocortex Drugs Boston University McLean Hospital jerry@chen‐lab.org [email protected] James Jeiwen Chou, Ph.D. Francis Ka‐Ming Chan, Ph.D. (2003 Award Recipient) (2003 Award Recipient) Structural Study of the Membrane‐Associated TNF‐Induced Programmed Cell Death in State of BID for Understanding BID‐Induced Immune Responses Damage of Mitochondrial Wall during University of Massachusetts Medical School Apoptosis [email protected] Harvard Medical School [email protected] Daniel L. Chase, Ph.D. (2006 Award Recipient) Damon Alistair Clark, Ph.D. Electrophysiological Analysis of Novel (2013 Award Recipient) Dopamine Signaling Mechanisms in C. Dissecting Motor Pattern Generating Circuits elegans in Walking Drosophila Central Connecticut State University Yale University [email protected] [email protected] 4 Steven Chuck, M.D. Alexei Degterev, Ph.D. (1997 Award Recipient) (2007 Award Recipient) Regulation of Apolipoprotein B Secretion Molecular Mechanism and Oncogenic Gilead Sciences Regulation of Cellular Necrosis [email protected] Tufts University School of Medicine [email protected] Andrew Connolly, M.D., Ph.D. (1998 Award Recipient) Walter E. Demkowicz, Ph.D. Endothelial Protease‐Activated Receptors (1995 Award Recipient) Stanford University School of Medicine Immunotherapy for AIDS: Transduction of [email protected] HIV‐1‐Specific T‐cell Receptor Genes University of Massachusetts Medical School Paul B. Cook, Ph.D. [email protected] (2000 Award Recipient) Modulation of Glycinergic Inhibition in the Li Deng, Ph.D. Vertebrate (1999 Award Recipient) Integrated Project Management A Chemical Approach Toward Understanding [email protected] DNA Modification Brandeis University David Daniel Cox, Ph.D. [email protected] (2013 Award Recipient) Learning How to See: a Biological and Stephanie Dougan, Ph.D. Computational Investigation of How Visual (2015 Award Recipient) Cortex Learns and Develops In Situ Delivery of Neoantigens and Targeted Harvard University Radiation in a Therapeutic Vaccine for [email protected] Pancreatic Cancer Dana‐Farber Cancer Institute Daniel H. Cox, Ph.D. [email protected] (2000 Award Recipient) Characterization of the Ca2+ Binding Sites of Elaine A. Elion, Ph.D. the Large‐Conductance Ca2+‐Activated K+ (1992 Award Recipient) Channel Mechanisms of Negative Growth Control in Tufts University School of Medicine Saccharomyces cerevisiae [email protected] Harvard Medical School [email protected] Michael Crickmore, Ph.D. (2015 Award Recipient) Patrick T. Ellinor, M.D., Ph.D. Molecular and Circuit Analyses of a (2003 Award Recipient) Motivational State The Genetics of Atrial Fibrillation: Exploration Boston Children’s Hospital of Endophenotypes [email protected] Massachusetts General Hospital [email protected] 5 Sean Elliott, Ph.D. Marc R. Freeman, Ph.D. (2004 Award Recipient) (2004 Award Recipient) Thioredoxins, Thioredoxin Reductase adn the Characterizing Core Components of the Glial Mechanisms of Oxidative Stress Cell Machinery Boston University University of Massachusetts Medical School [email protected] [email protected] Patrick Emery, Ph.D. Lillian Fritz‐Laylin, Ph.D. (2002 Award Recipient) (2019 Award Recipient) Circadian Rhythms and their Synchronization Defining Mechanisms of Pathogenesis of the in Drosophila “Brain‐eating Amoeba” University of Massachusetts Medical School University of Massachusetts Amherst [email protected] [email protected] Tamar Enoch, Ph.D. Robert C. Fuhlbrigge, M.D., Ph.D. (July 1993 Award Recipient) (1999 Award Recipient) Using Yeast to Identify New Tumor Regulation of CTCL Migration to Skin via CLA Suppressor Genes Brigham and Women's Hospital [email protected] Jerry Faust, Ph.D. (1992 Award Recipient) Jianmin Gao, Ph.D. Cloning and Initial Characterization of a Kidney (2007 Award Recipient) Specific Transporter for Mevalonic Acid Understanding Beta Sheet Structure within Tufts University School of Medicine the Membrane Bilayer [email protected] Boston College [email protected] Steven M. Finkbeiner, M.D., Ph.D. (1998 Award Recipient) Neil Joseph Ganem, Ph.D. Molecular Mechanisms of Huntington's (2014 Award Recipient) Disease Maintenance of Genome Stability by the Gladstone Institute of Neurological Disease Hippo Tumor Suppressor Pathway [email protected] Boston University School of Medicine [email protected] Matthew L. Freedman, M.D. (2006 Award
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