Direction de la recherche du CHU Sainte-Justine ÉTUDES MÉDIATISÉES DANS LES MÉDIAS ET SUR LE WEB Édition du 30 janvier 2013

September 28, 2012 Study of Dr. Gregor Andelfinger and Dr. Marc-Phillip Hitz Major genetic discovery explains 10 percent of aortic valve disease READ THE PRESS RELEASE Researchers at the Sainte-Justine University Hospital Center and University of have identified genetic origins in 10% of an important form of congenital heart diseases by studying the genetic variability within families. "This is more than the sum of the genes found to date in all previous studies, which explained only 1% of the disease, says Dr. Marc-Phillip Hitz, lead author of the study published in PLoS Genetics, under the direction of Dr. Gregor Andelfinger, pediatric cardiologist and principal investigator leading an international research team, who calls this study "a very important step towards a molecular catalog, which ultimately may explain the evolution of disease in individual patients and allow to influence the progression of the disease." MEDIA COVERAGE : Genome Québec Science Daily Continental News UdeMNouvelles Medical X Press AlphaGalileo Biospace Bioscholar Muckrack Healthfitnessok Breakthrough Digest Medical News Cours de médecine (5979 personnes suivent cette page sur Facebook)

October 31, 2012 Study of Dr. Grant Mitchell Confirmation of nitisinone efficacy for life-threatening liver disease READ THE PRESS RELEASE A consortium of Quebec researchers coordinated by the Medical Genetics Service of the Sainte- Justine UHC has just published the findings of a 25-year study on the treatment of tyrosinemia, a life-threatening liver disease of genetic origin, which is screened at birth in the province of Quebec, where it is much more frequent than anywhere else in the world. “After five years of treatment, no trace of the disease can be detected in the liver of newborns who were treated with nitisinone starting from the first month of life,” states Dr. Grant Mitchell of the Sainte- Justine UHC and the University of Montreal, who is the senior author of a study published in Molecular Genetics and in September 2012. MEDIA COVERAGE : Science Daily Doctor’s Guide News Medical Life Science Log Journal of Clinical Investigation Bio-Medicine Orphanet Journal of Rare Disease

November 15, 2012 Study of Dr. Gabriel Shapiro Eating more fish could reduce postpartum depression READ THE PRESS RELEASE Low levels of omega-3 may be behind postpartum depression, according to a review lead by Gabriel Shapiro of the University of Montreal and the Research Center at the Sainte-Justine Mother and Child Hospital. Women are at the highest risk of depression during their childbearing years, and the birth of a child may trigger a depressive episode in vulnerable women. Postpartum depression is associated with diminished maternal health as well as developmental and health problems for her child. “The literature shows that there could be a link between pregnancy, omega-3 and the chemical reaction that enables serotonin, a mood regulator, to be released into our brains,” Shapiro said. “Many women could bring their omega- 3 intake to recommended levels.” The findings were announced by the Canadian Journal of Psychiatry on November 15, 2012. MEDIA COVERAGE : Le Figaro The Huffington Post Herald Scotland Calgary Herald The Gazette Ottawa Citizen The Province The Vancouver Sun Agence Science-Presse The Times of India The Hindu New Kerala Windsor Star Lainformacion.com Europa Press Psych Central Mental Health Hub Medical Daily UPI.com Canada.com Yahoo! Actualités France MSN UK Yahoo! News India Techno-Science.net

November 19, 2012 Study of Dr. Marie-Claude Geoffroy, Dr. Jean Seguin and Dr. Sylvana Côté Daycare has many benefits for children, but researchers find mysterious link with being overweight READ THE PRESS RELEASE Young children who attend daycare on a regular basis are 50% more likely to be overweight compared to those who stayed at home with their parents, according to a study by researchers at the University of Montreal and the CHU Sainte-Justine Hospital Research Center. "We found that children whose primary care arrangement between 1.5 and 4 years was in daycare-center or with an extended family member were around 50% more likely to be overweight or obese between the ages of 4-10 years compared to those cared for at home by their parents,” said Dr. Marie-Claude Geoffroy, who led the study. “This difference cannot be explained by known risk factors such as socioeconomic status of the parents, breastfeeding, body mass index of the mother, or employment status of the mother.” MEDIA COVERAGE : CBC News Fox News Huffington Post New Zealand Herald Daily Mail Healthfinder.gov The Globe and Mail The Lindsay Post The Post The Star The Sudbury Star The Toronto Star HON News Sun News Toronto Sun Tucumán Noticias - Argentina Welland Tribune Beacon Herald Brantford Expositor Metro London Free Press MSN Canada Yahoo! News Canada Yahoo! News USA Medindia.net Medical news Canoe.ca 24hSanté.com Northumberlandtoday.com Simcoe Reformer Drugs.com Examiner.com Techno-science.net City News Deseret News KTAR Doctors Lounge Infobebes.com Magicmaman.com

December 17, 2012 Study of Dr. Julie Hussin and Dr. Philip Awadalla A genetic defect in sex cells may predispose to childhood leukemia READ THE PRESS RELEASE Researchers at the Sainte-Justine University Hospital Center and the University of Montreal have found a possible heredity mechanism that predisposes children to acute lymphoblastic leukemia (ALL), the most common type of blood in children. According to their findings published in Genome Research, the presence of a genetic defect in the egg or sperm that give rise to children with ALL may be a prerequisite for the disease to develop. A significant number of children with ALL are thought to inherit a rare PRDM9 gene variant responsible for the abnormal sex cells–a gene variant that puts their own children at risk of having ALL-predisposed offspring. MEDIA COVERAGE : Genome Québec Association québécoise d’établissements de santé et de services sociaux (AQESSS) Radio Canada International Journal de Montréal Medical News Today Synapse

January 14, 2013 Project leaded by Philip Awadalla Scientific Project Collects Health Data On 1 In 200 Quebecers READ THE PRESS RELEASE This is the largest recruitment in the general population for a scientific project on health that Quebec has ever known. Cartagene, the massive project which is currently building a bank of biological samples and detailed information on the health of Quebecers, is currently seeking 17,000 new candidates - men and women aged between 40 and 69 - in 6 regions of Québec: Gatineau, Montreal, Quebec City, Trois-Rivières, Saguenay and Sherbrooke. Participants will be asked to provide information about their health and their medical history and that of their family, as well as about their lifestyle. They will also be invited to provide a blood sample. All of this data will then be cataloged and stored at the Genome Quebec Chicoutimi Biobank. It will be used by researchers to support the discovery, amongst other things, of better diagnostics, treatments and prevention methods for chronic diseases known to be widespread in Quebec such as cancer, and . MEDIA COVERAGE : Le Soleil Le Devoir The Gazette La Presse/La Presse Canadienne /La Presse Canadienne La Tribune/La Presse Canadienne Le Nouvelliste Ottawa Citizen Huffington Post Journal Métro Le Journal de Montréal Le Journal de Québec Radio-Canada TV Radio-Canada TV - Téléjournal Radio-Canada International CBC News Montréal TVA Nouvelles 98.5 fm Montréal Yahoo! Québec - article MSN

Note : Les revues de presse ne sont pas exhaustives. Elles visent à donner un aperçu du type de couverture obtenue.

Nouvelle à médiatiser ? Adressez-vous à : Marise Daigle Conseillère en communications Centre de recherche du CHU Sainte-Justine [email protected] 514-345-4931, poste 3256 Bureau A-933

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