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Anti-SYT11 Antibody (ARG59976)

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Anti-SYT11 Antibody (ARG59976) Product datasheet [email protected] ARG59976 Package: 100 μl anti-SYT11 antibody Store at: -20°C Summary Product Description Rabbit Polyclonal antibody recognizes SYT11 Tested Reactivity Hu, Ms, Rat Tested Application ICC/IF, IHC-P, WB Host Rabbit Clonality Polyclonal Isotype IgG Target Name SYT11 Antigen Species Human Immunogen Recombinant fusion protein corresponding to aa. 37-200 of Human SYT11 (NP_689493.3). Conjugation Un-conjugated Alternate Names SYT12; sytXI; SytXI; Synaptotagmin XI; Synaptotagmin-11 Application Instructions Application table Application Dilution ICC/IF 1:50 - 1:100 IHC-P 1:50 - 1:100 WB 1:500 - 1:2000 Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. Positive Control Rat brain, Mouse brain and U251 Calculated Mw 48 kDa Observed Size 48 kDa Properties Form Liquid Purification Affinity purified. Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. Preservative 0.02% Sodium azide Stabilizer 50% Glycerol Storage instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. www.arigobio.com 1/3 Note For laboratory research only, not for drug, diagnostic or other use. Bioinformation Gene Symbol SYT11 Gene Full Name synaptotagmin XI Background This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that are known calcium sensors and mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. The encoded protein is also a substrate for ubiquitin-E3-ligase parkin. The gene has previously been referred to as synaptotagmin XII but has been renamed synaptotagmin XI to be consistent with mouse and rat official nomenclature. [provided by RefSeq, Apr 2010] Function May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. [UniProt] Cellular Localization Membrane; Single-pass membrane protein. Cell junction, synapse. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein. Note=In substantia nigra, observed in neuronal cell bodies and neurites. Found in the core of the Lewy bodies in the brain of sporadic Parkinson disease patients. [UniProt] Images ARG59976 anti-SYT11 antibody ICC/IF image Immunofluorescence: U2OS cells stained with ARG59976 anti-SYT11 antibody at 1:100 dilution. ARG59976 anti-SYT11 antibody IHC-P image Immunohistochemistry: Paraffin-embedded Human stomach stained with ARG59976 anti-SYT11 antibody at 1:100 dilution. www.arigobio.com 2/3 ARG59976 anti-SYT11 antibody WB image Western blot: 25 µg of Rat brain, Mouse brain and U251 cell lysates stained with ARG59976 anti-SYT11 antibody at 1:1000 dilution. ARG59976 anti-SYT11 antibody IHC-P image Immunohistochemistry: Paraffin-embedded Human liver injury stained with ARG59976 anti-SYT11 antibody at 1:100 dilution. www.arigobio.com 3/3 Powered by TCPDF (www.tcpdf.org).
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