2010 Final Program
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Autism Spectrum Disorder (ASD)
From: [email protected] To: [email protected] Subject: Condition Petition for Thomas Rosenberger Date: Tuesday, December 31, 2019 5:15:54 PM Attachments: Question 1 Autism.pdf Question 2 Autism.pdf Question 3 Autism.pdf Question 5 Autism.pdf This message was sent from the Condition page on medicalmarijuana.ohio.gov. Box was check regarding file size being too large to upload. Action needed! Name: Thomas Rosenberger Address: 815 Grandview Ave Suite 400, Columbus, OH, 43215 Phone: (614) 706-3782 Email: [email protected] Specific Disease or Condition: Autism Spectrum Disorder (ASD) Information from experts who specialize in the disease or condition. See attached file Question 1 Autism.pdf Relevant medical or scientific evidence pertaining to the disease or condition. See attached file Question 2 Autism.pdf Consideration of whether conventional medical therapies are insufficient to treat or alleviate the disease or condition. See attached file Question 3 Autism.pdf Evidence supporting the use of medical marijuana to treat or alleviate the disease or condition, including journal articles, peer-reviewed studies, and other types of medical or scientific documentation. File larger than 3MB Letters of support provided by physicians with knowledge of the disease or condition. This may include a letter provided by the physician treating the petitioner, if applicable. See attached file Question 5 Autism.pdf Question 1 Information from experts who specialize in the disease or condition Contents Overview – 3 Prevalence of Autism Spectrum Disorder Among Children Aged 8 Years — Autism and Developmental Disabilities Monitoring Network, 11 Sites, United States, 2014 – 4 Overview Autism spectrum disorder (ASD) is characterized by challenges with social skills, repetitive behaviors, speech and nonverbal communication. -
Promising Role for Gc-MAF in Cancer Immunotherapy: from Bench to Bedside
Caspian J Intern Med 2017; 8(4):228-238 DOI: 10.22088/cjim.8.4.228 Review Article Promising role for Gc-MAF in cancer immunotherapy: from bench to bedside Ehsan Saburi (PhD) 1, 2 Amin Saburi (MD) 3 Mostafa Ghanei (MD) *3 Abstract Immunotherapy has been used for years in many types of cancer therapy. Recently, cancer immunotherapy has focused on mechanisms which can enhance the development of cell- mediated immunity. Anticancer medications are administered to inhibit 1. Department of Cancer Research, Nastaran Center for Cancer immunosuppressive factors such as nagalase enzyme, which is produced by neoplastic Prevention, Mashhad, Iran. cells and destroys macrophage activating factor (Gc-MAF). Anti-neoplastics medications 2. Department of Molecular can also enhance immune-cell activity against tumors. Such medications show great Medicine, Zanjan University of potential in cancer immunotherapy using natural human mechanisms against neoplasms. Medical Sciences, Zanjan, Iran. 3. Chemical Injuries Research Keywords: Cancer, Immunotherapy, Macrophage activating factor, Gc-MAF, Vitamin D. Center, Baqiyatallah University of Medical Sciences, Tehran, Iran. Citation: Saburi E, Saburi A, Ghanei M. Gc-MAF promising role for cancer immunotherapy: From bench to bedside approach. Caspian J Intern Med 2017; 8(4): 228-238. * Correspondence: Mostafa Ghanei, Chemical Injuries Research Center, Baqiyatallah ancer is one of the most frequent and important causes of mortality and morbidity University of Medical Sciences, C Tehran, Iran. in humans. In developed countries, cancer imposes a huge cost in the health system. Although cancer therapy has advanced considerably in recent decades, the cancer mortality rate has continued to rise (1). Available cancer treatments vary and include chemotherapy (mitomysin, cisplatin), radiotherapy and biological-based medications (gene therapy, E-mail: [email protected] RNAi treatment, hormone treatment and immunotherapy) (2-4). -
(12) United States Patent (10) Patent No.: US 9,701.718 B2 Sullivan Et Al
US0097.01718B2 (12) United States Patent (10) Patent No.: US 9,701.718 B2 Sullivan et al. (45) Date of Patent: Jul. 11, 2017 (54) ADENOVIRUS SEROTYPE 26 AND (56) References Cited SEROTYPE 35 FILOVIRUS VACCNES U.S. PATENT DOCUMENTS (75) Inventors: Nancy J. Sullivan, Kensington, MD 6,852,324 B1* 2/2005 Nabel .................. CO7K 14f005 (US); Gary J. Nabel, Washington, DC 424,199.1 (US); Clement Asiedu, Olney, MD 7,094,598 B2 * 8/2006 Nabel et al. ............... 435/320.1 (US); Cheng Cheng, Rockville, MD 7,635,485 B2* 12/2009 Nabel .................... A61K 39,12 424,199.1 (US); Maria Grazia Pau, Leiden (NL); 7,635,688 B2* 12/2009 Nabel .................. CO7K 14f005 Jaap Goudsmit, Amsterdam (NL) 424.92 7,741,099 B2 6/2010 Havenga et al. (73) Assignees: Janssen Vaccines & Prevention B.V., 8,017,130 B2 * 9/2011 Nabel .................... A61K 39,12 424,199.1 Leiden (NL); THE UNITED STATES 8, 101,739 B2 1/2012 Sullivan et al. OF AMERICA, AS REPRESENTED 8, 106,026 B2 * 1/2012 Nabel .................. CO7K 14f005 BY THE SECRETARY, 424.92 DEPARTMENT OF HEALTH AND 8, 106,027 B2 * 1/2012 Nabel .................. CO7K 14f005 HUMAN SERVICES, THE OFFICE 424.92 OF TECHNOLOGY TRANSFER, 8,124,592 B2 * 2/2012 Nabel .................. CO7K 14f005 NATIONAL INSTITUTE OF 424.92 2004/0259825 A1 12, 2004 Nabel et al. HEALTH, Washington, DC (US) 2005/0196384 A1* 9/2005 Vogels et al. ................ 424.93.2 2006/0148087 A1 7/2006 Nabel et al. (*) Notice: Subject to any disclaimer, the term of this 2008/O1999.39 A1 8/2008 Havenga et al. -
Gcmaf: Our Next-Generation Immunotherapy
SPONSOR FEATURE SPONSOR FEATURE GcMAF: our next-generation immunotherapy Authors Saisei Mirai, based in Osaka, Japan, is a immunotherapy — such as dendritic cells, Yoshihiro Uto1, Hitoshi Hori1, Kentaro medical organization specializing in cancer autologous lymphocyte-activated killer Kubo2, Masamitsu Ichihashi3, Norihiro immunotherapy. The name Saisei Mirai is (LAK) cells, autologous NK cells, mono- Sakamoto3,4, Martin Mette5, Toshio Inui2,3,5 derived from the Japanese words for regen- clonal antibodies, cancer peptide vaccines, eration and future. It is our mission to cytokines, and biological response modifiers 1 Department of Life System, Institute provide cancer patients with the latest, most (BRM) — is rapidly advancing. However of Technology and Science, Graduate effective treatments while also ensuring the in a clinical setting, the results of cancer School, The University of Tokushima, 2-1 best possible quality of life. Cancer immu- immunotherapy are mixed. Minamijosanjima-cho, Tokushima, Japan. notherapy is the use of the immune system We therefore contend that cancer immu- to reject cancer. In particular, it involves notherapy should be customized to each 2 Saisei Mirai Cell Processing Center, stimulating the patient’s immune system individual patient based on their immune Nature21 Building 3F, 3-34-8 Okubo-cho, to locate and eliminate the cells that are status. We propose our next-generation Gc Moriguchi, Osaka, Japan. cancerous. This is achieved with immune protein-derived macrophage activating fac- cells such as Natural Killer cells (NK cells), tor (GcMAF) as a promising candidate for 3 Kobe Saisei Mirai Clinic, Kobe T Lymphocytes, Dendritic Cells (DC), and a patient-friendly cancer immunotherapy. Commerce Industry and Trade Center macrophages, among others.