bioRxiv preprint doi: https://doi.org/10.1101/467522; this version posted November 11, 2018. The copyright holder for this preprint (which was not certified by peer review) is the author/funder. All rights reserved. No reuse allowed without permission. Potassium channel regulators are differentially expressed in hippocampi of Ts65Dn and Tc1 Down syndrome mouse models Shani Stern1, Rinat Keren2, Yongsung Kim3 and Elisha Moses4 Affiliations: 1. Laboratory of Genetics, Gage Salk Institute for Biological Studies 10010 N Torrey Pines Rd La Jolla, CA 92037, USA Email:
[email protected] 2. Department of Physics of Complex Systems Weizmann Institute of Science P.O. Box 26, Rehovot 76100 Israel Email:
[email protected] 3. Laboratory of Genetics, Gage Salk Institute for Biological Studies 10010 N Torrey Pines Rd La Jolla, CA 92037, USA Email:
[email protected] 4. Department of Physics of Complex Systems Weizmann Institute of Science P.O. Box 26, Rehovot 76100 Israel Email:
[email protected] Postal address: Herzl St 234, Rehovot, 76100, Israel Corresponding Author: Elisha Moses Tel: +972-8-934-3139 Fax: +972-9-934-4198 Email:
[email protected] Keywords Down syndrome, Ts65Dn, Tc1, KCNE1, KCNE2, M-type, KCNQ2, KCNQ3, KCNJ6, KCNJ15, ion channels, hippocampus, qPCR, correlation in expression Abstract Background: bioRxiv preprint doi: https://doi.org/10.1101/467522; this version posted November 11, 2018. The copyright holder for this preprint (which was not certified by peer review) is the author/funder. All rights reserved. No reuse allowed without permission. Down syndrome remains the main genetic cause of intellectual disability, with an incidence rate of about 1 in 700 live births.