United States Patent Office Patented Aug
3,338,906 United States Patent Office Patented Aug. 29, 1967 1. 2 3,338,906 ples of alkylating agents are methyl iodide, butyl bromide, QUATERNARY AMMONIUM SALTS OF SUBSTI dimethyl sulfate. These alkylating agents result in a prod TUTED PHENANTHROLINES uct in which the anion is a halogen or sulfate. Other an Francis Patrick Dwyer, deceased, late of Griffith, New ions may be substituted by standard procedures using for South Wales, Australia, by Lola Mary Dwyer, execu example ion exchange resins or double decomposition re trix, Griffith, New South Wales, Australia, and Roy actions, for example, the saccharate anion may be im Douglas Wright, Parkville, Victoria, and Albert Shul posed as it has value in increasing the water-solubility of man, Prahran, Victoria, Australia, assignors to The Australian National University, Acton, Canberra, New the compounds; alternatively, anions such as stearate, South Wales, Australia, a corporation of Australia oleate, and the like may be imposed in order to decrease No Drawing. Filed May 24, 1963, Ser. No. 283,110 water-solubility of the compounds. A representative list Claims priority, application Australia, Jan. 26, 1960, of anions include sulfate, chloride, bromide, iodide, phos. 56,849/60 phate, nitrate, acetate, sulfamate, citrate, lactate, maleate, 8 Claims. (Cl. 260-286) malate, succinate, tartrate, cinnamate, benzoate, gluco nate, ascorbate, saccharate, stearate and oleate. This application is a continuation-in-part of application 15 Compounds in accordance with the invention are useful Ser. No. 84,533, filed Jan. 24, 1961. as therapeutic agents for the treatment of animal and This invention relates to new mono N-alkylated de plant diseases induced by a wide variety of organisms.
[Show full text]