CAMPUS HIGHLIGHT chicago

THE CHICAGO CAMPUS THE UNIVERSITY OF ILLINOIS COLLEGE OF AT GLANCE MEDICINE CHICAGO

Fewer than ten medical school The Department of Medical Education on the Chicago Campus is campuses in the country include the oldest continually operating university department devoted to the full range of health sciences scholarship in health professions education techniques. colleges, as does our Chicago Seven Chicago Campus departments of the College of Medicine Campus. The UIC colleges of rank within the top 30 departments nationally, within their discipline, medicine, public health, nursing, by amount of NIH funding—anesthesiology, biomedical engineering, dentistry, pharmacy, applied health emergency medicine, ophthalmology, pharmacology, psychiatry, and sciences, and social work are all urology. located here.

There are more than 800 residents THE CLINICAL EXPERIENCES AND ASSETS and fellows in training at the University of Illinois at Chicago and The College of Medicine provides students with extensive clinical its affiliated clinical institutions. experience early. Students on the Chicago campus train with patients beginning their first year at one of the eight teaching hospitals nearby. A new learning center devoted Students and residents experience a varied range of clinical to medical student educational opportunities and patient populations at the University of Illinois programming opened in 2015, Hospitals and Clinics, the Jesse Brown VA Medical Center, John H. following a $15 million renovation Stroger Hospital of Cook County, and several major local private of three floors of the historic affiliates including the hospitals of Advocate Health, the largest health College of Medicine West Tower. system in the metropolitan area. The Graham Clinical Performance Center, founded in 1957, was among the first facilities in the world WHY CHOOSE CHICAGO? to focus on performance-based clinical skills assessment. It will be The Chicago Campus serves a wide range of diverse and under-served replaced in 2019 by an $11 million patients from the neighborhoods near the Illinois Medical District, as simulation institute, now under well as other surrounding neighborhoods such as Little Italy, located construction. between the east and west campuses of UIC. The campus is located in proximity to various unique neighborhoods, such as Humboldt Park that The College of Medicine is offer distinguishing character to urban living. consistently ranked within the top The College of Medicine campus is also situated just two miles from 1/3 of US medical institutions the city’s downtown area, which offers restaurants of every style, cutting based on the amount of NIH edge music, concerts and events at Millennium Park on Chicago’s funding; UIC is one of only lakefront, State Street and Michigan Avenue shopping, esteemed art three universities in Illinois to be and science museums and so much more. considered a “highest intensity research” university by the Carnegie Convenient transportation makes it easy for students to become part Foundation for the Advancement of of this friendly, easy to adopt city; the perfect combination of big city Education. opportunity and small neighborhood quality of life. CAMPUS HIGHLIGHT peoria

THE PEORIA CAMPUS THE UNIVERSITY OF ILLINOIS COLLEGE OF AT A GLANCE MEDICINE PEORIA

About 240 medical students Known among students for its small class sizes and hands-on annually clerkships, the Peoria campus is located in Downtown Peoria’s Medical District within six blocks of more than 900 patient beds About 290 MDs and DOs in at its two primary clinical affiliate hospitals. 20 residency and fellowship programs Students in Peoria train within and have access to the world-class Two large healthcare systems Jump Trading Simulation & Education Center, a joint collaboration with a patient population of more with OSF HealthCare. Jump Simulation is a state-of-the-art than 2 million people medical training organization, research hub, and an international leader in simulation and innovation. World-class simulation center Diverse research opportunities: basic science and clinical THE CLINICAL EXPERIENCES AND ASSETS research, health outcomes and health economics, education, and Students in Peoria receive clinical training at two major affiliate simulation hospitals, OSF HealthCare Saint Francis Medical Center and UnityPoint Health—Methodist. Innovations in Rural & Global Medicine—an optional longitudinal, four-year track WHY CHOOSE PEORIA? Rural Student Physician Program—an optional Students say the small classes give you the chance to know the longitudinal, integrated clerkship faculty and attending physicians, and for them to know you. The classes are close-knit—peer education and peer mentoring is Engineering Internship for strong. You get the chance to experience hands-on medicine students interested in problem- across many specialties and subspecialties, often one-on-one solving and device development with attending physicians and resident physicians. The patient population is large and diverse, from urban to rural and across all Low cost-of-living ethnicities. The campus and affiliate hospitals offer a supportive Individualized social and learning environment for medical students. The city is big with professional support structure many amenities but easy to navigate and the cost of living is very affordable. Multidisciplinary research is supported and Numerous student groups and encouraged. Volunteer opportunities and student activities are activities plentiful. There’s a family-friendly feeling. CAMPUS HIGHLIGHT rockford

THE ROCKFORD THE UNIVERSITY OF ILLINOIS COLLEGE OF CAMPUS AT GLANCE MEDICINE ROCKFORD

Established in 1971, the College University of Illinois College of Medicine at Rockford offers medical education, of Medicine at Rockford has residencies and graduate education in eight departments. From biomedical since graduated more than science to surgery, each department boasts top faculty and groundbreaking 1,800 physicians, practicing in research that attract some of the best scientists and physicians in the country. The Rockford campus also takes pride in its world-renowned National Center all major specialties throughout for Rural Health Professionals which focuses on a clearly defined mission and Illinois and around the country. serves to broaden our ability to accomplish goals which would be more difficult The campus is particularly to tackle within the confines of a single department. well known as home to The National Center for Rural Health THE CLINICAL EXPERIENCES AND ASSETS Professions and the Rural The college of Medicine at Rockford offers the most extensive longitudinal Medical Education (RMED) ambulatory experience of any medical school in the country. Starting in the M2 Program. RMED trains medical year, our students are assigned to clinics for intensive, hands-on clerkships, students to meet the specific where they work closely with patients in a clinical setting. needs of rural communities. Through the National Center for Rural Health Professions (NCRHP) the The faculty based in Rockford College of Medicine works to improve health care in rural communities through numbers more than 470, in all education, evaluation and research. Students in our Rural Medical Education (RMED) Program are exposed to a cutting-edge, interdisciplinary curriculum major clinical specialties as well that prepares them to meet the needs of this underserved population. as educators and researchers in the biomedical sciences. WHY CHOOSE ROCKFORD? In the fall of 2017, the University of Illinois College of Medicine at Since 1971, the College of Medicine at Rockford has focused on building an Rockford (UI-COMR) expanded academic medical institution committed to education and advocacy, dedicated to research and continuous innovation, and centered on clinical service in the to provide all four years of surrounding communities. medical education in Rockford. The college transformed the The faculty at the College of Medicine at Rockford has pioneered cutting- edge contributions to the practice of medicine through groundbreaking curriculum, recruited new research, from studies on cancer and neuroendocrinology in the Department faculty and staff, and renovated of Biomedical Sciences to investigations of community-based health initiatives facilities. The impact of the M1 by the National Center for Rural Health Professions and the Division of Health capital project spending from Policy & Social Science Research. Our Office of Research offers extensive 2016–2035 resulted in added research support to faculty and students by mentoring and connecting revenue of about $33.9 million— students to researchers, consultation on study design, grant writing assistance, equivalent to creating 475 new statistical assistance, guidance with IRB applications and approvals and jobs. resources for potential funding mechanisms. Today, the College is a regional health sciences center. The campus is home to the regional College of Pharmacy program, the UIC College of Nursing advanced degree program, the master’s in medical biotechnology program, a public health certificate and Health Systems Research. RESEARCH

Our research goals are broad and ambitious, as are the needs and hopes of our patients. We aim to advance treatment now, and health in the future, by pursuing both fundamental insights and their application to the practice of medicine. Investigators across the College of Medicine are doing cutting-edge research in clinical medicine, in basic biomedical science, and in the translation of basic findings into clinical practice and societal health. Focus areas include cancer, women’s health, neurosciences, cardiac and vascular medicine, infectious disease, and obesity and diabetes.

STUDENTS’ RESEARCH The College of Medicine has (2013–2018) OVER 500 ENDOWED FUNDS to support its education, research, and patient care mission.

The College of Medicine RANKS IN THE TOP 1/3 of NIH-ranked institutions by research funding.

The University of Illinois College of Medicine is 1 OF 4 Basic Science Illinois universities boasting Biomedical Carnegie Foundation’s highest designation for research Outcomes/Health Services productivity. Policy

Epidemiology/Behavioral Studies FACES OF UNIVERSITY OF ILLINOIS COLLEGE OF MEDICINE

NANCY RODRIGUEZ THERESE KORNDORF (CHICAGO) WOODRING (PEORIA)

Urban Medicine (UMED) Program Center for Clinical and Translational AACAP Jeanne Spurlock Clinical Science Summer Fellowship at UIC Fellowship in Child and Adolescent Medical Research Scholars Psychiatry Program at the NIH Psychiatry Student Interest Group— Student Promotions Committee Class representative University of Illinois Urbana- American Medical Women’s Champaign College of Medicine Association - Junior Medical Research Symposium Student Mentor

FRANK EBAI AMER RASHEED (CHICAGO) (ROCKFORD)

Global Medicine (GMED) Program Society of Interventional Radiology Student National Medical Coordinator for the SIR-RFS Association (SNMA) Journal Club Post baccalaureate Admission Diagnostic and Interventional Program (PAP) Scholar Radiology Interest Group “Dreams don’t work, unless you do” College Committee of Admissions College Committee on Instruction and Appraisal Task Force on Assessment

JONATHAN JOU MARITZA ESTRADA- (PEORIA) O’BRIEN (ROCKFORD)

Jump Simulation Medical Latino Medical Student Engineering Internship Association—Copresident Music In Medicine—Cofounder Bridge Clinic Spanish Language Neurosurgery Interest Group— Interpreter President Family Medicine Interest Group— Peoria Student Government Class Representative Association American Medical Women’s University Medical Student Association Member Council—President Rural Medical Education Program Loaves and Fish Community Urban Health Program Medical Clinic volunteer PIONEERING CARE INSPIRED

MEDICINE The University of Illinois Hospital & Health Sciences System (UI Health) combines the resources of 7 health science colleges, a hospital, an urgent care center open evenings and weekends, an outpatient care center with 22 primary and specialty care clinics, and 13 Federally Qualified Health Centers (Mile Square Health Center) with locations throughout Chicago to provide a distinctive continuum of care. UI Health contains the largest and oldest continuously operating medical school in the country, which is why one out of every six physicians practicing in Illinois is trained at UI Health.

Patients at all of the campuses receive the highest level of care and attention medicine can provide. We offer everything from preventive medicine and routine check-ups to sophisticated surgeries and cutting-edge treatments. Our superbly trained medical teams are equipped with state-of-the-art technology to provide accurate diagnoses, effective treatments and cures.

University of Illinois College of Medicine educated physicians RANKED #1 in the 8th Annual Vitals Patients’ Choice Awards

The University of Illinois Hospital is RANKED IN THE TOP 10 hosptials in the Chicago Metro area and in Illinois for 2016–17 by USNWR

OSF Healthcare St. Francis Medical Center in Peoria is RANKED #6 in Illinois Fall Term Spring Term Summer Term Fall Term Spring Term

UI COM BLOCK 1 BLOCK 2 BLOCK 3 BLOCK 4 BLOCK 5 BLOCK 6 BLOCK 7 BLOCK 8 Phase 1 Body Systems Pathogenesis Skin, Muscle, Circulation & Digestion & Brain & Regulation & Synthesis Curriculum & & Movement Respiration Homeostasis Behavior Reproduction Homeostasis 1 2 Break – 8 weeks – 8 Break Synthesis – 1 week – 1 Synthesis week – 1 Synthesis week – 1 Synthesis week – 1 Synthesis week – 1 Synthesis week – 1 Synthesis

# of Weeks 7 Weeks 8 Weeks 5 Weeks 9 Weeks 7 Weeks 10 Weeks 5 Weeks 6 Weeks

Doctoring and Clinical Skills (doCS) Course Medical Colloquia Course THEMES Wellness, Personal Growth, and Reflective Practice Professional Career Development Development Professional Identity Formation I I I I Population Health Health, Illness, Vulnerable Populations and Society Health Humanities Lifestyle Medicine

Basic Science Oversight weeks+ – 6 1 Study Step Human Growth & Development Functional Evidence-Based Medicine Knowledge Diagnostic Tools Therapeutic Tools

Health Care Delivery Systems & Sciences Health Care Interprofessional Collaboration Systems Improvement, Innovation & Implementation

Clinical Skills Clinical Practice Doctor and Patient of Medicine Test Utilization and High Value Care CURRICULUM PHASE 2 AND PHASE 3* Our new curriculum integrates classroom and clinical learning

YR AUG I SEP I OCT I NOV I DEC JAN I FEB I MAR I APR I MAY JUN I JUL AY 2016–17 The order in which M3 and M4 experiences are scheduled varies for each student. Listed below are the required rotations and weeks of credit for each.

Essentials of Clinical Practice PEDIATRICS OB/GYNE PSYCHIATRY FAMILY MEDICINE SURGERY MEDICINE NEUROLOGY Option to fulfill and Professionalism 1 M3 M4 6 Weeks 6 Weeks 6 Weeks 6 Weeks 6 Weeks 8 Weeks 4 Weeks Weeks 2 Weeks

PATHWAY ELECTIVES TRANSITION COURSES 16 Weeks 4 Weeks (Choose one Pathway) SUB- Hospital-Based Medical Surgical Pathway Essentials of Clinical Practice & INTERNSHIP Pathway Pathway OPEN ELECTIVES M4 Professionalism 2 (1) 14 Weeks 4 Weeks Radiology (4) Radiology (4) Radiology [Surgery/Anatomy] (4) Laboratory Medicine (2) Emergency Medicine (4) Emergency Medicine (4) Anesthesiology (4) Longitudinal Career Medical Selective (4) Dermatology (4) Cardiopulmonary Selective (4) Development (1) Surgical Selective (4) Medical Selective (4) Surgical Selective (4)

*SOME ELEMENTS OF THE M3 AND M4 ACADEMIC YEARS OF THE NEW ILLINOIS MEDICINE CURRICULUM HAVE NOT BEEN FINALIZED, SUCH THAT DETAILS OF THIS DIAGRAM ARE SUBJECT TO CHANGE Aug SPECIAL CURRICULAR PROGRAMS Jul I 3 / F CLINICIAN EXECUTIVE MEDICINE (CE-MED) 2 2 C Jun e 1 This program is available at all sites m, ftos ft,c P' P CE-MED trains students in the skills and knowledge essential to addressing the complex leadership challenges resulting from healthcare organizational and health policy changes that impact the way clinicians provide care. terms) 4 ( l May

L GLOBAL MEDICINE (GMED) M4 M3

(3 Available at the Chicago campus only - of

Aug GMED trains students to be global health leaders. With an emphasis on addressing global health equity, students Ma, as will gain skills and knowledge to develop careers as global clinicians, educators, policy makers, or researchers. Apr E., late

as INNOVATION MEDICINE (IMED) or Available at the Chicago campus only Step1 USMLE Mar re11uir..menis B I( IMED provides a systematic approach to innovation in clinical practice through co-curricular and interdisciplinary terms), 1 1 E J 2H

Curriculum activities related to medical product design. The program seeks to develop innovators who draw from advances in technology and clinical expertise to solve real-world problems. degree {thr'ee Feb M3 RURAL GLOBAL MEDICINE (IRGMED)

".ir Available at the Peoria campus only Structure as rn•1ed M3

1 IRGmed offers medical students the opportunity to experience health care and health care delivery models in nol Jan early Medicine 1(A)(18weeks)

Ma- low resource settings. Students accepted into the program grain a deep understanding of the barrier as as haw Term 2 PATIENT-CENTERED MEDICINE (PCM) who ei!ffy Phase

Dec Available at the Chicago campus only as ,hose plete

Illinois PCM affords students selected as PCM Scholars a unique opportunity to work with culturally and exceplforPhaGe begin fo, socioeconomically diverse patients, from the M1 through the M4 years. This educational endeavor is an L corr

can outstanding example of a curricular innovation that draws upon the passions and motivations of students, the Nov A

l'Tlil'.f knowledge and expertise of our multi-faceted faculty, and creates learning experiences that directly benefit 1e,m The 1 D J patients. I 2G e 3 16weeks, o• ft partial curriculum siudent P

3 RURAL MEDICINE (RMED)/RURAL STUDENT PHYSICIAN PROGRAM (RSPP) Oct tennis RMED—available at the Rockford campus only/RSPP available at the Peoria campus only gr.en Each Fhase A Opliooal RMED and RSPP were developed to train and support physicians in rural Illinois and beyond. The curriculum focuses on developing the interprofessional knowledge, skills, and attitudes required of rural health professionals. Sept URBAN MEDICINE (UMED) Available at the Chicago campus only

Aug UMED is for students who plan, upon completion of residency training, to practice in urban communities in specialties needed by those communities. This unique program integrates special UMED activities with the medical school curriculum. M1 M2 M3 M4 Health Care Systems Clinical Practice of Health, Illness Development Foundational Professional and Society Knowledge program. throughout the is emphasized and clinical sciences integration of basic sciences; thus the physical, and behavioral the basic biological, understanding of solving based on an and clinical problem rational decision making stressesThe curriculum Medicine THEMES CURRICULUM - PHASE I Body SystemsBody and Homeostasis 1 7 Weeks Block 1 Block

Fall Term medicine.uic.edu Synth. 1 wk Pathogenesis 8 Weeks Block 2 Block

Synth. 1 wk Skin, Muscle and Movement 5 Weeks Block 3 Block Spring TermSpring Wellness, Personal Growth and Reflective Practice Improvement, Innovation and Implementation Synth. 1 wk Health Care Systems and Sciences Delivery Doctoring and Clinical Skills (DoCS) Course and Clinical Skills (DoCS) Doctoring Contact Information Circulation and Respiration Test Utilization and High Value Care Human Growth and Development 9 Weeks Professional Identity Formation Block 4 Block Interprofessional Collaboration M3 M4 YR CURRICULUM - PHASE II & III The order in which M3 and M4 experiences are scheduled varies for each student. Listed below are the required rotations and weeks of credit for each. Evidence-Based Medicine Evidence-Based Medical ColloquiaMedical Course Basic Science Oversight Science Basic Vulnerable Populations Central Admissions Regional Student Affairs Offices Career Development ESSENTIALS OF CLINICAL ESSENTIALS OF CLINICAL Health Humanities Doctor and PatientDoctor Lifestyle Medicine Lifestyle Population Health Therapeutic Tools PROFESSIONALISM 1 Diagnostic ToolsDiagnostic AUG SUB-INTERNSHIP Clinical Skills PRACTICE AND University of Illinois Chicago Rockford 4 Weeks 2 Weeks College of Medicine Admissions Office 1853 W. Polk (MC 785) 1601 Parkview Avenue

E C O E A E A APR MAR FEB JAN DEC NOV OCT SEP Synth. 1 wk 808 South Wood Street (MC-783) Chicago, IL 60612-7332 Rockford, IL 61107 Homeostasis 2 Digestion and Digestion mrec eiie()EegnyMdcn 4 Anesthesiology (4) Medicine (4) Emergency Medicine (4) Emergency PEDIATRICS Surgical Selective (4) Medical Selective (4) Surgical Selective (4) Surgical Selective (4) Selective Medical (4) Surgical Selective Medical Selective (4) Dermatology (4) Cardiopulmonary Selective (4) Selective Cardiopulmonary Dermatology (4) (4) Selective Medical 7 Weeks 6 Weeks Block 5 Block Summer TermSummer

HOSPITAL-BASED Room 165 CME P: (312) 996-2450 P: (815) 395-0600 Radiology (4) Radiology PATHWAY Chicago, IL 60612-7302 I-LINE 815-395-5842 Peoria P: (312) 996-5635 OB/GYNE 6 Weeks 1 Illini Drive F: (312) 996-6693 Peoria, IL 61605 16 Weeks (Choose Pathway) One Synth. 1 wk Email: [email protected]

MEDICAL PATHWAYMEDICAL P: (309) 671-8411

BreakBrain and Behavior 8 wk PATHWAY ELECTIVES IMPASSIONED • INSPIRED • INNOVATIVE Radiology (4) Radiology PSYCHIATRY 6 Weeks 10 Weeks Block 6 Block MEDICINE 6 Weeks FAMILY MEDICINE Fall Term [Surgery/Anatomy] (4) SURGICAL PATHWAYSURGICAL Synth. 1 wk Radiology Radiology Regulation and Reproduction SURGERY 8 Weeks Together we will shape the future of medicine. 5 Weeks Block 7 Block MEDICINE Essentials of Clinical Practice 8 Weeks and Professionalism 2 (1) Laboratory Medicine (2) TRANSITION COURSES Longitudinal Career Development (1) MAY 4 Weeks Spring TermSpring

Synthesis medicine.uic.edu 6 Weeks Block 8 Block NEUROLOGY (Optional) 2 Weeks U JUL JUN

ELECTIVES ELECTIVES 14 Weeks OPEN Option toOption fulfill M4 Weeks Step 1 Study - 6 Weeks+

P1801306 COM Admissions Brochure.indd 1 1/31/18 5:22 PM THE UNIVERSITY OF ILLINOIS COLLEGE OF MEDICINE SHAPING THE BEST AND BRIGHTEST MINDS

HAS ONE OF THE MOST DIVERSE STUDENT BODIES INTO THE MEDICAL LEADERS OF TOMORROW THE ENVELOPE PLEASE... OF ANY MEDICAL SCHOOL IN THE U.S. MAKING THE MATCH Our mission is to produce new knowledge in the medical sciences, develop best practices in health NATIONAL RESIDENCY MATCHING PROGRAM care delivery, and educate the next generation of physicians and biomedical scientists committed Four years of training, In anticipation of that very to serving the needs of Illinois and the nation. fours years of waiting for important day, we prepare the one moment that will our graduates to provide chart the course to the rest compassionate patient care, to of their career. That’s the demonstrate leadership and life of a medical student. advocacy in health care, to Their fate is determined by provide care for underserved one small envelope on one urban and rural populations, CAMPUSES very special day, Match Day. and to translate research Our The day's results determine discoveries into clinical practice. welcoming where they will complete environment and diverse their residency training. student body engender deeper learning and provide new perspectives on life. Come 2017 MATCH DAY FAST FACTS experience the strength of multiple voices, races, cultures, beliefs, TOP 5 STATES TOP 5 SPECIALTIES CHICAGO CAMPUS PEORIA CAMPUS ROCKFORD CAMPUS identities, orientations and points of view. 1. Illinois (29%) 1. Internal Medicine (21%) 137 307 2. California (9%) Match 2. Emergency Medicine (10%) • Located in the heart of • Located in a 900-plus • Intensive academic and Programs Participants 3. Missouri (6%) Represented 3. Family Medicine (8%) one of the largest urban hospital bed medical comprehensive clinical 4. Massachusetts (5%) 96% 4. Pediatrics (8%) medical districts in the U.S. district in downtown training for students 5. Tie: Michigan, Minnesota, 5. Anesthesiology (6%) RANKINGS & Match Peoria New York (5%) Rate 28 • As early as the first year, • Home to the National Specialties FAST FACTS Represented medical students have • Early longitudinal clinical Center for Rural Health access to an extraordinary immersion experience Professions and the science education, as Rural Medical Education Ranked “Top 100 Producers” in 2008, • Small class sizes and Ranked third for graduation of Asian well as extensive clinical Program RANKED by Diverse Issues in Higher Education SPECIALIZED PROGRAMS exceptional facilities American students in 2013 by Diverse exposure to a diverse 3RD TOP 100 • #1 for Hispanic graduates and • Expanded health science Issues in Higher Education CLINICIAN EXECUTIVE GLOBAL MEDICINE INNOVATION MEDICINE RURAL MEDICINE URBAN MEDICINE and underserved patient • Students train in Jump • #5 for African American graduates campus —the recently MEDICINE (CE-MED) (GMED) (IMED) (RMED)/RURAL (UMED) population at one of the Simulation, a world leader completed $26 million Learn a systematic STUDENT PHYSICIAN Gain the skills and Learn how to be a global Cultivate the skills district’s eight teaching in medical simulation and health leader. With an approach to innovation PROGRAM (RSPP) renovation and expansion knowledge essential to needed to practice in hospitals innovation Hispanic Business magazine ranked us emphasis on addressing in clinical practice, Develop the specialites needed by project, established a new Ranked third for graduation of addressing the complex • Clinical experience at two among the “top 10 medical schools for through co-curricular and interprofessional • Medical Scientist Training Master’s Degree program RANKED Hispanic students in 2013 by Diverse leadership challenges global health equity, urban communities upon TOP 10 Hispanic students” in it’s 2008 annual interdisciplinary activities major affiliate hospitals 4TH Issues in Higher Education students will gain skills knowledge, skills and completion of residency Program, a combined in medical biotechnology, rankings resulting from healthcare related to medical product attitudes required of MD/PhD program that with a patient base and partnership with the organizational and health and knowledge to develop training. This program design through advances population of 2 million careers as global clinicians, rural health professionals integrates special UMED prepares students for Colleges of Pharmacy, policy changes that in technology and clinical educators, policy makers in Illinois and beyond. activities with the people and 20 residency impact the way clinicians expertise to solve real- careers in academic Nursing, and Public Health 1 of 6 physicians in Illinois have received a medical degree or resident training from the College of Medicine. and fellowship programs provide care. or researchers. world problems. medical curriculum. medicine and research

P1801306 COM Admissions Brochure.indd 2 1/31/18 5:22 PM A publication of the University of Illinois College of Medicine volume 21 number 1 spring 2018 ILLINOIS MEDICINE Inspired Education. Innovative Research. Impassioned Patient Care.

MEDICINE’S NEXT FRONTIER Brain health the focus for researchers around COM, across UIC

COM changes culture of education, emphasizing resilience | Educational leaders flow from pipeline at COM, UIC Cancer foe Emil Freireich named Pioneer in Medicine | Alumni reunite while Gala ignites fundraising campaign Our mission is to enhance the health of the citizens of Illinois by educating physicians, biomedical scientists and innovators, advancing knowledge of health and disease, and providing health care in a setting of education and research.

Education We are committed to our educational strategies and to the enhancement of student achievement and leadership. We provide an innovative active-learning educational environment for our diverse body of students, and we are implementing plans to achieve the convergence of engineering and medicine as well as modernize the physical T educational spaces in the historic College of Medicine building.

Research The College of Medicine will further focus research endeavors on fostering interdisciplinary collaborations in clinical and basic science departments, incorporate engineering-based medical research, and translate this research into clinical applications, including those that address unmet medical needs.

Clinical Care We strive to provide value-based, personalized medical care as well as accessible, affordable technological advances to our community in coordination with the University of Illinois Hospital & Health Sciences System as we expand our academically distinct clinical and translational programs. dean’s message III

HE HUMAN BRAIN IS A CENTRAL ORGAN that governs much of our physical and mental well- being, yet it remains one of the most mysterious biological structures. Although medicine has made significant discoveries in the last 30 years about how the brain functions, we have only just scratched the surface of understanding its complexity. Our cover story this issue takes an in- depthT look at how researchers both within the COM and across the University are collaborating to chart new paths and gain insight into this next frontier of medicine—through such diverse areas as anatomy and cell biology, neurology and rehabilitation, neurosurgery, advanced imaging, and psychiatry. Additionally, while the College of Medicine has been implementing a broad curricular update starting with our incoming class of first-year medical students this year, we have also taken a closer look at the well-being and resiliency of our students. The modern medical student encounters a variety of PHOTO: DIANE SMUTNY stressors and pressures to understand and achieve in the profession. One aspect of our new curriculum aims to address burnout, anxiety, depression and social isolation by encouraging and teaching coping strategies. We know that students who practice self-care are equipped with the tools to become effective and impactful physicians who care for the health of others. In training the next generation of medical education experts domestically and internationally, the College of Medicine offers a master of health professions education (MHPE) degree, while the Chicago campus of the University of Illinois provides an executive master of health administration (EMHA) program. Graduates of these programs are based across the U.S. and beyond pursuing careers that influence the way we teach the practice of medicine to not only medical students, but also the teachers and leaders in medicine. The impact of our gold-standard department of medical education goes far beyond the walls of our college—it influences medical schools around the globe. This past fall, we also celebrated our tradition of excellence with our many outstanding alumni and donors. During our annual reunion, visitors heard about the many changes to the college’s facilities and curriculum as well as groundbreaking faculty research. Visitors also attended the Illinois Medicine Gala, where they feted Root Society members and the 2017 Illinois Medicine Award winners: Emil Freireich as Pioneer in Medicine, Terry Mason as Distinguished Alumnus, Janet Lin as Emerging Innovator, Bruce Gillis as Innovator of Today, and James and Marion Grant for the Spirit of Medicine, all of whom are profiled in this issue. The Gala also launched the fundraising campaign for the COM as part of “IGNITE: The Campaign for UIC,” as we celebrated the exciting future of medicine that happens here. We hope that all of our alumni and friends will participate in this campaign because you are truly the spark that ignites our future. As UIC Chancellor Michael Amiridis said as he quoted Greek philosopher Plutarch: “A mind is not a vessel to be filled, but a fire to be kindled.” f Charles E. Ray Jr., MD, PhD, MS Interim Dean, Professor of Radiology

ILLINOIS MEDICINE | 1 COLLEGE OF MEDICINE ADMINISTRATION

INTERIM DEAN Charles E. Ray Jr., MD, PhD, MS

REGIONAL DEAN, PEORIA Sara L. Rusch, MD, Res ’81, FACP

REGIONAL DEAN, ROCKFORD Alex Stagnaro-Green, MD, MHPE ’05, MHA ’17

ACTING REGIONAL DEAN, URBANA-CHAMPAIGN Janet A. Jokela, MD, MPH

SENIOR ASSOCIATE DEAN FOR EDUCATION Raymond H. Curry, MD, FACP

ASSOCIATE DEAN FOR DIVERSITY AND INCLUSION Gloria Elam, MD, MPH

ASSOCIATE DEAN FOR COLLEGE STRATEGIC INITIATIVES Patricia Finn, MD

ASSOCIATE DEAN FOR ADMISSIONS Jorge A. Girotti, PhD

PRESIDENT OF WOLCOTT, WOOD AND TAYLOR, INC. AND CBO OF MEDICAL SERVICE PLAN Frank Goldberg, PhD

ASSOCIATE DEAN FOR DEVELOPMENT AND VP, UIF Stephanie Grinage

ASSOCIATE DEAN FOR STRATEGIC COMMUNICATION Ilene Harris, PhD

SENIOR ASSOCIATE DEAN FOR STUDENTS Kathleen Kashima, PhD

ASSOCIATE DEAN FOR EXECUTIVE DEVELOPMENT Jay Noren, MD, MPH

ASSOCIATE DEAN FOR TECHNOLOGICAL INNOVATION AND TRAINING Bellur Prabhakar, PhD

SENIOR ASSOCIATE DEAN FOR RESEARCH Larry Tobacman, MD ASSOCIATE DEAN FOR CLINICAL AFFAIRS AND EXECUTIVE DIRECTOR OF MEDICAL SERVICE PLAN Patrick A. Tranmer, MD

ASSOCIATE DEAN FOR ADMINISTRATION Todd Van Neck, MPP

ASSOCIATE DEAN FOR FACULTY AFFAIRS William Walden, PhD

ASSOCIATE DEAN FOR EDUCATIONAL PLANNING AND QUALITY IMPROVEMENT Sandra Yingling, PhD

ILLINOIS MEDICINE EDITORIAL STAFF

PUBLISHER Todd Van Neck, MPP

EDITOR IN CHIEF Michael J. Wesbecher, MPH features EDITORIAL BOARD Stephanie Grinage; Ilene Harris, PhD

MANAGING EDITOR HOLISTIC MEDICAL EDUCATION Ed Finkel COPY EDITOR A Curricular Prescription for Well-Being 12 Maria Mooshil

CONTRIBUTING WRITERS As the College of Medicine institutes an innovative and updated curriculum, it is also focused on Richard Asa, Dan Baron, Carla Beecher, changing the culture of medical education to foster resilience and guard students against anxiety, Melissa Maleske, Ian Murphy, Alice Patenaude, Susan Reich, Rose Shilling, depression, burnout and social isolation Daniel Smith, Cheryl SooHoo DESIGN COVER STORY Anne Boyle, Boyle Design Associates

PHOTOGRAPHY Lloyd DeGrane, Diane Smutny, Daryl Wilson, Maximizing Brain Health 16 UIC News Services Researchers from the COM and around the UIC campus are collaborating to uncover the mysteries COVER: Man x-ray by Adimas, Adobe Stock of the human brain and discover cures, in such diverse disciplines as anatomy and cell biology, Illinois Medicine is a publication of the University neurology and rehabilitation, neurosurgery, and psychiatry of Illinois College of Medicine Office of the Dean. ©2018 All rights reserved. TEACHING LEADERS All inquiries should be addressed to: Illinois Medicine Office of Medical Advancement (MC 792) Educating Medical Educators 21 1747 W. Roosevelt Road, Suite 302 WROB Chicago, Illinois 60608-1203 The COM’s Master of Health Professions Education (MHPE) program and UIC’s broader Executive Phone: (312) 996-4470 Email: [email protected] Master of Health Administration (EMHA) program are training the next generation of medical www.medicine.uic.edu education experts in the U.S. and beyond Volume 21, Number 1 Spring 2018 ILLINOIS MEDICINE departments

GALA AND CAMPAIGN LAUNCH 1 Dean’s Message Igniting a New Future in Medicine 24 4 Campus News Gala honors Root Society members, Illinois Medicine Award winners—and lights the spark for the 10 Faculty News College of Medicine’s piece of UIC’s IGNITE fundraising campaign 32 Alumni Engagement COM REUNION 34 Class Notes

Alumni Reminisce, Reflect 26 41 In Memoriam COM alumni from the 50th reunion class and others return to reminisce with one another and reflect on the many changes to the college, its facilities and curriculum; they also hear about some 48 Five Questions recent faculty research during IL Med Talks

ILLINOIS MEDICINE AWARDS COM Honors Cancer Pioneer Emil Freireich 28 Freireich (Pioneer in Medicine), Terry Mason (Distinguished Alumnus), Janet Lin (Emerging Innovator), Bruce Gillis (Innovator of Today), and James and Marion Grant (Spirit of Medicine) received Illinois Medicine Awards for 2017

ILLINOIS MEDICINE | 3 campus news

CHICAGO PEORIA ROCKFORD URBANA-CHAMPAIGN

LAUNCHING A NEW ERA OF MEDICAL EDUCATION COM begins updated curriculum and welcomes M1s in Peoria and Rockford

OR THE FIRST TIME IN DECADES, the University of Illinois own knowledge and address their individual interests and needs based upon their College of Medicine is ushering in a dramatic change to the way aptitudes and intended pursuits.” medical students are taught across all campuses. The 2017-2018 academic year marked this phasing in of the new curriculum, After many months of assessment and preparation, faculty, starting with the new M1s in the class of 2021 in Chicago, Peoria and Rockford. administrators and students this school year have launched A process the COM started formulating in 2015, the redesigned approach to the updated Illinois Medicine Curriculum, which has brought medical education is more tightly focused on clinical relevance and integrates consistency and standardization across the multiple COM sites perspectives on basic, clinical and social sciences alongside themes of health as the Peoria and Rockford campuses also welcomed first year care systems, health and society, and professional development to allow students medical students, expanding their programs to become full four- to contextualize how these aspects influence the delivery of modern health care. year medical school curricula. The updated curriculum offers earlier clinical experience to students, thematically “Our innovative approach to medical education is based on the idea blocked information, and a more holistic approach that includes such topics as Fof evolving the one-size-fits-all method of teaching that has been used student wellness and resilience (see p. 12). for decades,” says Raymond Curry, MD, FACP, senior associate dean for Peoria Regional Dean Sara Rusch, MD, Res ’81, underscores that this new educational affairs. “The updated curriculum will ensure that students are approach better positions the school among peers and within the wider medical proficient in all learning objectives, while also allowing students to assess their community. “We are phasing in a new curriculum that is more clinically relevant,

ROCKFORD (this page) The College of Medicine and Rockford communities came together to celebrate the updated facilities on the Rockford Health Sciences Campus in August 2017. The 56 first-year medical students who started in Rockford later that month have started using updated spaces such as the virtual anatomy lab and clinical skills simulation areas.

PEORIA (opposite page) To welcome 58 new first- year students last fall, Peoria opened 10,000 square feet of newly renovated educational spaces including a technology-rich Learning Studio, a new anatomy wing and a “student oasis.” The updated spaces were dedicated during an open house celebration that welcomed alumni and the Peoria community last July. PHOTOS: LLOYD DEGRANE AND CARRIE HERMANSON LAUNCHING A NEW ERA OF MEDICAL EDUCATION COM begins updated curriculum and welcomes M1s in Peoria and Rockford

provides greater clinical experiences, incorporates broader areas of health, uses impact study, the coming of these M1 students will also add $2.2 million in innovative educational methodologies, and focuses on student wellness and annual economic impact to the community.” resilience,” she says. “Whether they want to become a primary care physician in In addition to updated educational offerings across the college, Peoria a rural community, a neurosurgeon or an academic, we are preparing them with and Rockford needed to modernize and build teaching and learning spaces to the skill sets they need.” accommodate the additional first-year medical students. During the fall of 2017, Students are taught by employing thematically blocked content, including Peoria welcomed 58 first-year students whille Rockford had 56 first-year medical pathogenesis, circulation and respiration, and brain and behavior, among other students at orientation. themes. Each blocked sequence is then capped with a synthesis week that In Peoria, new educational spaces include a technology-rich Learning offers students the opportunity to reflect and see where they need additional Studio, a new anatomy wing and a “student oasis,” which totaled about 10,000 understanding of concepts. This approach offers greater ownership and direction square feet of renovations. Similarly, in Rockford, the educational spaces were of the learning process to students themselves. updated to also include an anatomy lab and additional group work areas. Given “These first-year students receiving all four years of medical education in that the new Illinois Medicine Curriculum is designed around the concept of Rockford will allow them to become more involved with the community, pursue team-based learning, these spaces needed to offer the flexibility for large and long-term research projects and create lifelong ties to Rockford,” says Rockford small-group learning. Regional Dean Alex Stagnaro-Green, MD, MHPE. “Based on our economic — Michael Wesbecher

PHOTOS: DARYL WILSON PHOTOGRAPHY

ILLINOIS MEDICINE | 5 LEADERS IN EMERGENCY FORM SIREN COM joins national emergency medicine network

HE COLLEGE OF MEDICINE HAS JOINED a newly formed national network that will T collaborate to conduct clinical trials aimed at improving outcomes for emergency room patients. The network, called SIREN (Strategies to Innovate EmeRgENcy Care Clinical Trials Network), will pool resources and boost patient numbers for emergency medicine clinical trials. “The SIREN network enables us to COM Unveils recruit patients across dozens of hospitals CELLS THAT and lets us focus on determining the best Regenerative ways we can care for vulnerable patients,” Medicine, Stem ‘GO OUT WITH says Marina del Rios, MD, assistant professor of emergency medicine at Cell Center the COM and co-principal investigator A BANG’ on SIREN. THE COLLEGE OF MEDICINE HAS Trials that tap into SIREN will have LAUNCHED a new center to focus on ‘Exploding’ cells access to minority and underserved understanding tissue regeneration and contribute to high death populations that have traditionally been pioneering future developments in stem rate in bloodstream left out of clinical trials. Patients enrolled cell biology to repair diseased organs and in SIREN clinical trials will be tracked after tissues. The University of Illinois Center infections they leave the ER to follow outcomes. for Stem Cell and Regenerative Medicine SIREN is a nationwide network is the first in Chicago dedicated to these COM RESEARCHERS have found that of emergency departments led by 11 topics with a focus on basic biology and cells lining blood vessels in the lungs clinical centers called hubs. COM is part translational science. exposed to bacterial toxins called of the Mid-America SIREN Hub, which Researchers in the new center are lipopolysaccharides don’t die easily— also includes Northwestern Medicine, investigating the molecular signals that instead, an explosive form of cell death University of Chicago, Indiana University, drive stem cells to mature into different known as pyroptosis occurs. And this the University of Texas Southwestern, and cell types, as well as studying the epigenetic contributes to a high death rate among the Medical College of Wisconsin. regulation of stem cells; the best approaches those who experience acute lung injury. to transplant engineered cells, tissues “There are multiple ways a cell can and organs; and methods to efficiently die,” says Jalees Rehman, MD, associate produce the regenerative cells needed professor of medicine and pharmacology for novel treatments. in the COM and co-lead author on the “The center will use a team-oriented, paper, published in the Journal of Clinical multidisciplinary approach that incorporates Investigation. “In pyroptosis, cells go out experts in biochemistry, biophysics, with a bang.” bioengineering and the clinical sciences Acute lung injury, experienced by to investigate stem cell biology and tissue approximately 200,000 people in the regeneration,” says Asrar Malik, PhD, the U.S. every year, can be fatal in 30 to 40 Schweppe Family Distinguished Professor percent of cases. The current standard and head of pharmacology, who is guiding treatment is supportive care, such as the effort. artificial ventilation. The current program in stem cell “Our work shows that pyroptosis of biology and regenerative medicine already endothelial cells that line blood vessels includes seven faculty members, most may be one of the reasons why bacterial within the department of pharmacology, infections can cause such severe injury who together have more than $10 million in to the lung in some patients,” says research grants from the National Institutes Asrar Malik, PhD, Schweppe Family of Health. Three new faculty members have Distinguished Professor and head of joined the center in the last two years, and pharmacology, and co-lead author on Malik expects to add more. the paper.

6 | SUMMER 2017 NARROWING HEALTH DISPARITIES New health equity research center established on Chicago campus

he University of Illinois at Chicago has received $6.75 million from the National Institutes of Health to establish a specialized Center of Excellence in minority health and health disparities research. The Center for Health Equity Research (CHER) will investigate how social determinants impact the health of marginalized groups. “The vast majority of preventable disease in the U.S. happens in a small group of minority communities,” says TRobert Winn, MD, associate vice chancellor for community- based practice on the Chicago campus and director of the University of Illinois Cancer Center, who is corresponding INNOVATIONS principal investigator. “These groups are socially disadvantaged due to geography, poverty or IN MEDICAID discrimination based on race, ethnicity, gender or sexual COM collaboration with orientation.” CHER will focus initially on MeridianHealth wins ‘best three research projects, one of which will be led by COM assistant professor of medicine Lisa Tussing-Humphreys, PhD, MS, RD, a fellow of the Institute practice’ award for Health Research and Policy, who along with colleagues will study how colorectal cancer risk in the black community correlates to experiences of HE COLLEGE OF MEDICINE’S COORDINATED HEALTH racism. CARE FOR COMPLEX KIDS (CHECK) program, a “The end goal is to get to a point where my health and your health is collaborative effort with MeridianHealth, has received not determined by the color of our skin, where we live, or who we live with,” the “2017 Most Innovative Best Practice” award in the says Jesus Ramirez-Valles, PhD, professor and director of community health Children’s Health category from the Institute for Medicaid sciences in the UIC School of Public Health. Innovation. Martha Daviglus, MD, PhD, associate vice chancellor for research at The partners have focused on Medicaid-enrolled UIC, says a second goal of CHER is to invest in the career development of children with complex medical conditions and chronic minority researchers. UIC is one of 12 centers nationwide and the only one in diseasesT to fill the gaps in service that this population faces. The joint the Midwest to be funded by the NIH’s Health Disparities’ Center of Excellence submission, “A Model of Care: Care Coordination for Complex Kids,” program. The COM is one of seven entities at the university to participate. is a program focused on reducing healthcare costs, absentee school rates, and fostering better patient and family engagement in care UIC faculty and administrators (from left) Jesus Ramirez-Valles, Martha Daviglus and management. Robert Winn are pleased with the $6.75 million NIH grant the campus received to establish The CHECK program focuses on four main conditions: diabetes, the Center for Health Equity Research, which will examine how social determinants impact sickle cell disease, asthma and prematurity, says Pamela Roper, MD, the health of marginalized groups. MPH, pediatrician at the University of Illinois Hospital & Health Sciences System. But it goes beyond simple treatment. “CHECK is a program R HICAGO 0 CHER CHICAGO that focuses on the non-medical barriers to healthcare,” she says. Adds Andrea Pappalardo, MD, another pediatrician and an allergist-immunologist at UI Health, “We’re making people feel ,GO empowered to take charge of their own health care by maybe finding transportation to the pharmacy, if they don’t have it, [or] maybe helping with a three-way call, navigating through the ridiculous amount of prompts in making an appointment.” Benjamin Van Voorhees, MD, MPH, head of pediatrics for UI Health, says the system chose the four conditions because they’re difficult to manage, result in missing school days and thus can lower likelihood of high school graduation, and also they’re very costly to the health system. “[Providers] work seamlessly together to understand the unique situation of every particular child,” he says. “This keeps the communication flowing better. It’s a way to use each one’s skills more efficiently.” PHOTO: UI CANCER CENTER

ILLINOIS MEDICINE | 7 DOES CHRONIC INFLAMMATION CONTRIBUTE TO OVARY DYSFUNCTION? PHOTO: LLOYD DEGRANE NIH-funded study will look at effects of anti-inflammatory drug COM Peoria Professor Ken-ichiro Fukuchi has received a nearly $440,000 grant to expand a study that has examined the possible connection between eating a high-fat diet and contracting Alzheimer’s disease. on polycystic ovary syndrome

HE COLLEGE OF MEDICINE CHICAGO HAS RECEIVED A DIET AND RISK $3 MILLION FEDERAL GRANT to COM-Peoria receives two-year NIH grant study the effects of inflammation on polycystic ovary syndrome. to study Alzheimer’s disease Affecting one in seven women, TPCOS is an endocrine system disorder that disrupts the menstrual cycle and impedes T’S WELL-KNOWN THAT THE FOOD WE EAT can have a short-term impact on our waistline, but ovulation. longer term it can have implications for our brain health, according to COM researchers. The study, funded by the National The latter will be the focus of a nearly $440,000, two-year grant that Ken-ichiro Fukuchi, MD, Institutes of Health, will look at the role PhD, a professor in cancer biology and pharmacology at the COM Peoria, has received from the of inflammation in 90 women with PCOS. National Institutes of Health. He will expand a study examining a link between a high-fat diet and Principal investigator Frank González, MD, greater risk for Alzheimer’s disease. says the goal is to understand the underlying Fukuchi’s research focuses on a specific molecule, a type of microRNA, that’s elevated in the mechanisms of the syndrome. blood of animal models with Alzheimer’s disease and with Type 2 diabetes. “These increased levels “While we have made great strides induce brain endothelial cell dysfunction, or a dysfunctional blood-brain barrier, which lead to an in helping women with PCOS, we need increased risk or early onset and accelerated progression of Alzheimer’s disease,” Fukuchi says. “More more research to understand exactly what Iimportantly, we believe this microRNA may provide new strategies for therapies or prevention against happens in the body to cause the ovaries Alzheimer’s disease.” to malfunction,” says González, associate A high-fat diet is strongly associated with obesity, insulin resistance, and Type 2 diabetes, professor of obstetrics and gynecology, and while sustained alterations in blood glucose levels caused by obesity and Type 2 diabetes promote director of the laboratory for reproductive vascular inflammation and blood-brain barrier impairment. The latter, in turn, is believed to lead to endocrine and inflammation research. the accumulation of toxic plaques, neuroinflammation, neuronal dysfunction, neurodegeneration, and González and his research team will ultimately dementia and Alzheimer’s disease. randomize patients into two groups. The Determining the role microRNA plays in the inflammation and dysfunction in the blood-brain barrier control group will receive a placebo, and could stop this domino effect and halt the progression of Alzheimer’s disease, which affects more than 5 the study group will receive a nonsteroidal million people in the U.S. “An urgent need exists to identify the molecular mechanisms that increase the anti-inflammatory drug called salsalate. “We risk of Alzheimer’s disease and to develop preventive and therapeutic measures,” Fukuchi says. expect that women with PCOS receiving salsalate treatment will exhibit evidence of ovulation, decreased ovarian androgen secretion and reduced inflammation,” González says.

8 | SPRING 2018 UI HEALTH JOINS SUPPORTIVE Renewed Grant for Rockford ONCOLOGY COLLABORATIVE Health Education Program HE NATIONAL CENTER FOR RURAL HEALTH PROFESSIONS, NIVERSITY OF ILLINOIS HOSPITAL & HEALTH SCIENCES part of the College of Medicine Rockford, has received five SYSTEM HAS JOINED A ONE-OF-A-KIND PARTNERSHIP to bring additional years of competitive grant funding totaling nearly supportive oncology tools and resources to cancer-care providers $6.9 million from the U.S. Health Resources and Services in the Chicago area. Administration. UI Health physicians and medical staff, including Mary The HRSA grant will go for the continuation of the Illinois Pasquinelli, NP; Ana Gordon, LSW; Eileen Knightly, RN, BSN, MHA; Area Health Education Center (IL AHEC) Network Program, UKent Hoskins, MD; Khari Reed, MHSA; Larry Feldman, MD; Marisa Carpinelli, Testablished in 2010, which has eight regional centers throughout the state, AM, LCSW; Nilofer Kidiwala, DO; Oana Danciu, MD; and research technician including one jointly based Zane Deliu, are among 135 providers from 35 Chicago-area health systems at the COM Chicago working with the Supportive Oncology Collaborative. campus and the UIC The SOC, established and funded by The Coleman Foundation in School of Public Health. 2014, designs and tests process improvements, creates screening tools The centers serve and training, and advocates with payers to cover supportive oncology care both rural and urban services. Aimed to address cancer patients’ psychological, social, physical underserved residents and practical concerns, these services are delivered by multidisciplinary teams through access to of oncologists, physician assistants, social workers and clergy. health professions “University of Illinois Hospital & Health Sciences System is proud to be education, health careers a part of this unique partnership,” Pasquinelli says. “Their work has created development, and evidence-based tools and resources that are available to all cancer-care community and public providers so their patients may have access to the physical, emotional and health promotion activities. psychological support they need.” The grant funding will allow for the continuation and expansion of these programs and the establishment of a ninth regional AHEC center serving the suburban counties around Chicago. Through previous network efforts, more than 60,000 participants have The Supportive been a part of Illinois AHEC-supported programs, which are part of the Coleman National AHEC Organization developed by Congress in 1971. Oncology Collaborative --·----

PROVIDING AID FOR HIV/AIDS POPULATION Peoria HIV/AIDS program receives $1.25 million renewal from HUD for low-income sufferers

HE COLLEGE OF MEDICINE “There’s a lot of additional expenses with PEORIA WILL RECEIVE $1.25 this disease that makes it hard to make MILLION over the next three ends meet.” years from the U.S. Department A stable home is critical to the well- of Housing and Urban being of those living with HIV/AIDS and Development to assist low- results in better health outcomes and Tincome people living with HIV/AIDS and reduced transmission of the disease, their families. HUD says. The grant will provide rental The local grant, aimed at those assistance, including case managers and in central Illinois, is a small slice of $37 social service coordinators, for up to 55 million in nationwide awards announced people living in central Illinois during each in December by HUD to provide a of the three years. The grant also will combination of housing assistance and provide permanent housing placement supportive services for this vulnerable services for up to 75 people over the population. three-year period. “This is designed to provide Briggs says there is a waiting list at assistance to individuals living with HIV and to help establish stable housing,” says the moment, but she adds that as people become more stable, they hopefully Pam Briggs, director of administrative operations at Positive Health Solutions, a will be able to transition to private housing and no longer need the funding program based at the COM Peoria that has provided comprehensive medical care assistance, allowing others living with HIV to receive grant funding. Similar and services to persons living within a 15-county area in central Illinois since 1994. assistance was provided in a previous three-year grant from 2014 to 2017.

ILLINOIS MEDICINE | 9 . sl 'J. faculty news

The latest accomplishments of our distinguished faculty

AZAR RESIGNS AS EXECUTIVE DEAN; cognition and mood. Maki’s studies and the founder of have identified female-related risk the International RAY BECOMES INTERIM DEAN factors for brain aging and dementia School of Robotic Dimitri Azar, MD, MBA, stepped down as in healthy women and women living Surgery, which executive dean of the College of Medicine on with HIV. She is past president of the since 2003 has March 15, and Charles Ray, MD, PhD, MS— North American Menopause Society, trained more than acting dean since Azar took a leave of absence chair of the Society for Women’s 750 surgeons from Health Research Interdisciplinary 24 countries. in July 2017—was named interim dean. The Pier Giulianotti College dean since 2011, Azar will continue as Network on Alzheimer’s Disease, senior director of ophthalmologic innovation and immediate past head of the ALTER RECEIVES SEE at Verily Life Sciences while remaining on Neurocognitive Working Group of the the COM faculty on a part-time basis as Women’s Interagency HIV Study. Maki HUMANITARIAN OF THE professor of ophthalmology, bioengineering has won numerous NIH awards for YEAR AWARD and pharmacology, as well as B.A. Field Chair her research and service. She serves in Ophthalmologic Research. An internationally as a research Daniel Alter, MD ’92, PhD ’93, has recognized ophthalmic surgeon, Azar joined Dimitri Azar and career received a 2017 Humanitarian of the the COM in 2006 as head of the department mentor to Year Award from SEE International, of ophthalmology & visual sciences. During his tenure as dean, the College myriad students in honor of World Sight Day, and to made significant advances across all of its campuses in areas like learner- and junior recognize the outstanding dedication centered education, clinically relevant translational research and high-quality faculty, sits and achievement of volunteer patient care. Previously, Azar served as a tenured professor of ophthalmology on executive ophthalmologists committed to ending at Harvard Medical School, director of the Cornea Service at Massachusetts committees for avoidable blindness worldwide. Alter Eye & Ear Infirmary, senior scientist at Schepens Eye Institute, and a faculty several women’s Pauline Maki has traveled to Haiti 12 times over member at Johns Hopkins School of Medicine. Before Ray became acting health advisory the past two years to assist citizens dean, he served as head of the department of radiology at the COM for more boards, and appears frequently as an of the poorest country in the Western than four years, and he is an accomplished clinician and researcher with more international and national speaker on Hemisphere, and one that has been than 18 years of administrative experience. A pioneer in translational research menopause and women’s cognitive devastated by natural disasters over focusing on oncologic interventions and pain management, Ray served as and mental health. Maki received her the past decade. The country’s public president of the Society of Interventional Radiology from 2016-17 and has PhD from the University of Minnesota health care system been on the executive council of the society for 12 years. and postdoctoral training at the Johns has suffered as a Hopkins University School of Medicine result, and access and the National Institute on Aging. to basic vision care is extremely GIULIANOTTI limited, yet Haiti DAVIS WINS LIEBER PRIZE data; his group published the has the highest second meta-analysis overall and APPOINTED VISITING prevalence of FOR SCHIZOPHRENIA the first in the field of psychiatry. PROFESSOR AT blindness in Latin Daniel Alter RESEARCH The results indicated that patients America and the with schizophrenia were less likely CHINESE UNIVERSITY Caribbean. With a practice in Des John Davis, MD, Gilman Professor to have relapses if they took their Pier Cristoforo Giulianotti, MD, Plaines, Illinois, for more than 20 years, of Psychiatry and anti-psychotic medications for the a pioneer and world-renowned Alter has affiliations at both Advocate Research in the long term, a concept now well known surgeon in robotic-assisted surgery, Lutheran General Hospital and Amita COM, has won as maintenance therapy. Currently, has been appointed as a visiting Health Elk Grove Village. He interned the Lieber Prize Davis is studying gene expression professor at Guangxi Medical at MacNeal Hospital, did residency at in Outstanding abnormalities in schizophrenia and University in China for a three-year the University of Illinois Eye and Ear Achievement in conducts clinical trials addressing term. The university recognized Infirmary, and returned to the COM Schizophrenia the disease. his professional achievements and for fellowship. Research also wished to promote mutual from the Brain John Davis MAKI RECOGNIZED exchange in medical education, FIGUEROA WINS & Behavior research and training. Chief of the Research Foundation. A giant in WITH AMWA WOMAN IN division of general, minimally invasive, HMPRG HEALTH & the field, Davis and his colleagues SCIENCE AWARD and robotic surgery at UI Health, MEDICINE AWARD introduced the notion that major Giulianotti was the first surgeon in mental illness may be caused by Pauline Maki, PhD, senior research the world to perform a significant Evelyn Figueroa, MD ’99, has won biochemical abnormalities, and director of the Center for Research series of complex robotic procedures a 2017 HMPRG Award from Health his group was among the first to on Women and Gender at the COM and has personally performed more & Medicine Policy Research Group study the pharmacodynamics and Chicago, has received the Woman than 2,000 robot-assisted surgeries. for her service as a leader in policy, pharmacokinetics of psychotropic in Science Award from the American Giulianotti, who also serves as Lloyd public health, medicine, research, and drugs. Davis also helped develop the Medical Women’s Association. Her Nyhus Chair in Minimally-Invasive and advocacy whose work exemplifies statistical method known as meta- research over the last 20 years has Robotic Surgery, is the director of the Health & Medicine’s mission to analysis as a way to pool scientific focused on menopause, sex steroids, Robotic Clinical Fellowship Program promote social justice and challenge

10 | SPRING 2018 - J_ __

inequities in health and health care. A professor of clinical family medicine HOLTERMAN EARNS INNOVATIVE RESEARCH AWARD who serves as assistant dean for Mark Holterman, MD, PhD, a professor of surgery and pediatrics clinical affairs, outpatient in the COM at the COM Peoria, has earned an Innovative Research Award from Chicago, Figueroa the American Diabetes Association for groundbreaking research has developed conducted through the Core Research Program. Previously honored innovative with the same award from ADA, Holterman has spent more than programs to help 20 years as a practitioner at OSF St. Francis Medical Center. The learners better American Diabetes Association has supported more than 5,000 understand research initiatives in the field of diabetes over the past 60 years, how to care funding research work in diabetes etiology and addressing the for vulnerable challenges faced by researchers in studies that use humans as Evelyn Figueroa populations. A research subjects. A specialist in pediatric surgery, Holterman’s faculty member research interests include novel cancer treatment, stem cell Mark Holterman at the COM since 2005, she practices therapy and regenerative medicine. He earned his MD and PhD traditional family medicine, caring from University of Virginia and undertook a fellowship in pediatric surgery at the University of Washington and Seattle for patients of all ages, and she has Children’s Hospital. Holterman previously worked at Rush University Medical Center as an attending pediatric surgeon. additional expertise in women’s health and maternity care.

MICHEL EARNS RIFKIN NAMED CHAIR OF MEDICINE IN ROCKFORD FULBRIGHT, WILL Gary Rifkin, MD, has been named chair of the department of COLLABORATE WITH medicine at the College of Medicine Rockford. A professor of CRISTANCHO clinical medicine and infectious diseases, Rifkin joined the faculty of the COM in 1978 and has served in various roles in teaching, Joanna Michel, PhD ’06, instructor administration and clinical practice, including the vice chair and of medical education at the COM acting chair for the department of medicine. Rifkin has won several Chicago and associate director of university awards, including three Golden Apple Teaching Awards, the University of Illinois at Chicago the Distinguished Service Award, Distinguished Teaching Award Urban Medicine Program, has and two Council for Excellence in Teaching and Learning Awards. received a Fulbright U.S. Scholar A graduate of the Albert Einstein College of Medicine in New York, Program award to study how women Rifkin completed an internship and residency in internal medicine displaced from rural to urban areas in and an infectious disease fellowship at the University of Michigan Gary Rifkin Medellin, Colombia, use medicinal and Medical Center. He is board-certified in internal medicine and nutritional plants infectious diseases and is a fellow of the American College of Physicians and the Infectious Diseases Society of America. in their health care He maintained a clinical practice with Rockford Infectious Disease Consultants and served as physician epidemiologist at practices. Also an several area medical centers from 1978 until 2012. affiliate professor in the UIC School of Public Health, Michel is one of 800 faculty and LEOW CO-LEADS WINNING MOOD DISORDER RESEARCH TEAM Joanna Michel professionals who are Alex Leow, MD, PhD, an associate professor of both psychiatry traveling abroad during the 2017- and bioengineering, has co-led a team of researchers that has won 2018 academic year through the the Mood Challenge for ResearchKit. That’s a contest launched program, the flagship international by the Robert Wood Johnson Foundation to come up with new educational exchange sponsored by ways to study mood disorders using Apple’s ResearchKit, an open- the U.S. government. Her four-month source platform for creating iOS apps. The team of researchers at research project is a collaboration with the University of Illinois at Chicago, also co-led by Peter Nelson, Sergio Cristancho, PhD, assistant PhD, professor of computer science and dean of the College of professor at the COM Rockford and Engineering, along with collaborators at the University of Michigan professor of public health at the and Sage Bionetworks, developed a mobile app called BiAffect. Universidad de Antioquia in Medellin. The app unobtrusively monitors device usage, including keyboard Alex Leow The project will center on how dynamics such as typing speed, to predict manic and depressive dramatic migration to urban areas episodes in people with bipolar disorder. The BiAffect team will receive the $200,000 grand prize to continue to refine caused by ongoing armed conflict in and launch its app in the App Store. “The vision for BiAffect is for it to serve as a kind of ‘fitness tracker’ for the brain,” Colombia has changed women’s use Leow says. “The Mood Challenge helped us to realize this vision, and the finished app will be a first-of-its-kind tool for of plants for medicinal and nutritional researchers to study mood disorders and even cognitive disorders such as Parkinson’s and Alzheimer’s disease.” BiAffect purposes. also will help researchers determine the efficacy of different treatments for bipolar and other mood disorders.

ILLINOIS MEDICINE | 11 holistic medical education

by Susan Reich

A Curricular Prescription for WELL-BEING As the College of Medicine rolls out its innovative new curriculum, first-year students are already reaping the benefits of a wellness-oriented approach to medical education

concluded that medical students need the tools to heal themselves as It’s three months into Aisha Bhatti’s they prepare for a lifetime of caring for others. first year at the College of Medicine’s Educational evolution Rockford campus. But Bhatti isn’t in IN 2015, THEN-COM EXECUTIVE DEAN DIMITRI AZAR, MD, MBA, class or hitting the books at the moment. invited administrative leaders, faculty, staff and students across the Surrounded by a handful of other medical students seeking a college’s campuses to brainstorm how to change the culture of medical temporary respite from the rigors of preclinical coursework, she’s education to support higher levels of student well-being and resilience. dipping her brush into a vivid green glob of paint and dabbing it onto It was a synergistic moment to initiate such a conversation. the nature scene taking shape on her canvas. Totally absorbed in the Raymond Curry, MD, FACP, senior associate dean for educational act of creation, she hasn’t thought about her upcoming block exam for affairs, had just launched the college’s first curriculum redesign in a full 45 minutes. more than three decades. “I have a background in art, so I was excited when I first heard “We believe that our students should thrive, not just survive,” Iabout these art therapy workshops,” recalls the 23-year-old Glenview says Abbas Hyderi, MD ’01, MPH, associate dean for curriculum. “Our native a few months later. “Of course, like every other medical student, objectives were to promote individual well-being while sustaining my first thought was, ‘I should study instead.’ But I decided to go for academic performance; address student anxiety, depression and it, and I was so glad that I did. I came out of that workshop feeling burnout; and train future physicians to serve as role models while relaxed and happy. It was very cathartic to use a different part of my supporting the well-being of their patients and peers.” brain.” Geri Fox, MD ’83, MHPE ’04, associate dean for wellness and Bhatti’s art therapy experience is just one of the new programs resilience, studied medical student well-being and mapped out a designed to foster medical student resilience and well-being at the robust wellness curricular approach that would help students manage COM’s Chicago, Peoria and Rockford medical campuses. It’s also a the demands of medical school while taking better care of themselves. sign of the changing culture of medical education as the University This undertaking would lead Fox, a professor of clinical of Illinois and other top schools mobilize to address medical student psychiatry, and the members of the Task Force on Student Well-Being stress, depression and burnout. and Resilience deep into the inner workings of the medical student Although the depression rate for students entering medical psyche. They explored the debilitating effects of fatigue and social school is roughly comparable to that of their nonmedical peers, the isolation, the divisive nature of a competitive class ranking system, prevalence of depression increases disproportionately among medical and the feelings of futility and burnout arising from the preclinical students over the course of their education and training, according to a firehose of information students must master. study published in The New England Journal of Medicine. “Our overall goal as we mapped out this curricular approach A Mayo Clinic study of more than 4,200 students at seven was to help medical students learn how to help themselves and their U.S. medical schools found that roughly half (49.6 percent) of RIGHT: Although she keeps her nose to the medical school grindstone most of the time, student medical students were suffering from burnout, and 11.2 percent had Aisha Bhatti has found short breaks for wellness activities like art therapy workshops to be experienced suicidal ideation within the past year. The COM has reinvigorating both personally and academically.

12 | SPRING 2018 PHOTO: LLOYD DEGRANE As the College of Medicine rolls out its innovative new curriculum, first-year students are already reaping the benefits of a wellness-oriented approach to medical education

PHOTO: LLOYD DEGRANE ILLINOIS MEDICINE | 13 THE POETRY OF MEDICINE

s there a place for poetry in medical school? Kristi Kirschner, MD, thinks so. I When first-year medical students were learning about anatomy, in came the Poetry Foundation to conduct a small group activity about the body that involved writing poems about cadavers, says Kirschner, a visiting clinical professor in the College of Medicine’s department of medical education and the leader of the Health Humanities Curriculum task force in the new COM curriculum. Kirschner and her fellow task-force members—who represent the fields of medical PHOTOS: DIANE SMUTNY history, philosophy and ethics, First-year medical students at the COM have been the first cohort to experience and provide sociology, disability studies feedback about the updated Illinois Medicine Curriculum, which was rolled out in August and integrates and literature in medicine— a wellness framework in a variety of ways. have spent nearly two years integrating experiences Kristi Kirschner patients make better choices that support health and happiness,” says like this into the new Illinois Fox, who oversees the wellness and resilience curricular components Medicine Curriculum. Tied into curricular themes, these new at the three COM campuses. “We recognize that advocacy is needed on health humanities experiences range from philosophical many fronts to improve the national health care system’s inadequate discussions about professional ethics, to a conversation with a support for physician wellness. The wellness curriculum is intended to disabled artist about using art to hone observation skills about help our highly competent students stay resilient in the face of these the body. challenges.” Students also have a chance to sample a variety of elective The new Illinois Medicine Curriculum, which was rolled out to health humanities experiences through medical colloquia. Students can choose to participate in such activities as a writing first-year students in August 2017, represents a radical departure from group, a graphic medicine session (a relatively new field that the traditional—or “classic” medical school curriculum (see Campus uses comics in health care education), a panel discussion with News, p. 4). patients talking about living “We’ve integrated wellness into this new framework in a variety with illness or disabilities, or of ways,” explains Fox. “For instance, if the students have a case BODY EI.EC::TRI<:: engagement with a medical study about a patient with panic attacks, we may include relevant ,_.,._.._,~ ..-~ ..- historian about the way information for medical students about anxiety. During each synthesis medicine has treated bodily week [immediately after exams], the students have two hours set aside differences over time. COM for a wellness plenary, which is followed by small group discussions.” artists have also re-energized These have covered topics such as recognizing burnout, sleep hygiene Body Electric, a journal of literary and visual arts and the importance of self-compassion. Fox emphasizes that medical created by medical students students are invited to suggest other areas in which the COM also can with support from faculty improve support. members in the department Gerald Wickham, MA, EdD, assistant dean for medical education of medical education. and evaluation in Peoria, surveyed M1 students midway through the “Our students spend a current academic year to gather data about the wellness programming lot of time in medical school in general and the plenaries in particular. Of the 67 percent of first- studying diseases and drugs years who responded to the survey, nearly all (92 percent) said the and cells, but to apply all of that knowledge in the context of a curriculum on wellness was an important part of their medical human life requires an understanding of the patient experience school experience, 71 percent felt they had gained new insights about at the human level,” Kirschner says. “Things don’t always wellness, and 66 percent believed that the synthesis week wellness present clearly or neatly in medicine. We believe that working with different modalities in the arts and humanities can help plenaries had improved their well-being. students understand how to deal with ambiguity and uncertainty, The survey results are heartening to Meenakshy Aiyer, MD, which is a very large part of medicine.” — Susan Reich FACP, associate dean for academic affairs in Peoria. “This positive

14 | SPRING 2018 PHOTO: DIANE SMUTNY

Cory Reiter, an MD/PhD candidate in the Medical Scientist Training Program, has helped lead efforts to survey students on their wellness going into board exams, organize peer-to-peer support, launch an online mental health screening tool with the Counseling Center, and bring mental health to the west campus by making a counselor available weekly to medical students. But most important, she says, have been efforts to encourage students to talk about wellness, both to remove stigma and to underscore the fact that caring for oneself is a skill set that requires training and persistence to refine. feedback shows that we are making progress as we work together to support the well-being of their peers in a variety of ways, from bringing build a community of competent and caring future physicians who in massage therapists, to organizing events to relieve student stress, to demonstrate self-compassion and have a sense of work-life balance. advocating for the installation of a Farmer’s Fridge vending machine on This will help them to provide high-quality, compassionate care for the medical campus, which fuels students around the clock with salads, their patients while caring for themselves as well,” she says. fruits and other healthy offerings. Kathleen Kashima, PhD, senior associate dean of students in Chicago, sees the teaching of wellness as self-perpetuating. “If our A new culture of well-being students learn the fundamentals of personal well-being during medical school, they will pass on that knowledge when they become residents ALTHOUGH IT REMAINS A WORK IN PROGRESS, the holistic and faculty and start teaching the next class of medical students,” wellness and resilience program is already sparking a culture change. she says. “We need to promote and empower wellness in our patients,” says Connie Vitali, MD, assistant dean for medical education and evaluation Student-led support in Rockford. “But, to do this, shouldn’t physicians be well themselves? By intentionally teaching our students how to take care of themselves, EACH CAMPUS IS ALSO DEVELOPING its own extracurricular we are laying the groundwork for a culture change that will profoundly wellness programs, an endeavor that has benefited greatly from the affect not only physicians but also their patients. There’s some hidden commitment and enthusiasm of a committed corps of student leaders. gold here that we are not going to see until these students hit their third One of these leaders is Cory Reiter, an MD/PhD candidate in the and fourth years and move into their internships.” Medical Scientist Training Program in Chicago. Reiter, who helped “We know that stress is inevitable in medical school,” reflects Terri develop the new curriculum as member of both the Student Curricular Blevins, MA, EdD, Rockford assistant dean for student and alumni Board and the Student Wellness and Resilience Committee, is now affairs. “But we are already seeing signs that we are helping our students helping to expand extracurricular wellness programs as chair of learn how to deal with this stress in a healthy way. The students love the latter. the small group discussions about different aspects of well-being and A passionate advocate for student wellness, Reiter’s sense of report that they feel very supported and connected to the faculty and mission grew out of personal experience. “When I was a pre-med one another. They’ve already orchestrated a number of extracurricular student, I had a sick mom, and that was a priority that I couldn’t activities amongst themselves, from a murder mystery dinner to a compromise on,” she confides. “So I compromised on other things, potluck night and a barn dance. As I watch this class, I’m seeing some such as going out with friends, or going to the gym, or cooking healthy real moments of joy.” food. What I learned is that you can only push yourself like that for Bhatti credits the new culture of wellness with helping her maintain so long before it begins to have an impact on your cognitive acuity or a better school/life balance. “The new curriculum not only facilitates your emotional stability.” learning and makes the first-year experience less stressful, but gives me Reiter and her fellow wellness committee members continue to some time to engage in pursuits that help me recharge,” she says.

ILLINOIS MEDICINE | 15 clinical impact

by Alice Patenaude

MAXIMIZING BRAIN HEALTH 16 | SPRING 2018 Understanding the complexities of How Illinois the human brain, and expanding the possibilities to prevent or treat the sometimes-devastating diseases that Medicine affect brain health, are among the elusive pieces of a complex medical puzzle. College of Medicine researchers are working with colleagues from around the University of Illinois at Chicago campus and beyond to is unraveling crack the code, attempting to understand the structure and Ufunction of the brain itself by using big data to decipher cures for degenerative diseases; de- one of veloping quantitative tools that optimize treatment for stroke patients; and finding the most effective treatments to improve medicine’s mental-health issues. Energized by the priority placed on brain health research by UIC Chancellor Michael D. Amiridis, PhD, faculty from biggest such diverse disciplines as biology, bioengineering, psychology, neurology, neurosurgery, psychiatry, and anatomy and cell biology are collaborating across campus with one focus: creating discoveries and advancements in the areas of brain health that will most directly mysteries benefit patients. They are making progress on all fronts. Anatomy and cell biology: Deciphering degenerative diseases

TO GET TO THE ROOT OF BRAIN DISEASE, the depart- ment of anatomy and cell biology begins with the basics: trying to understand the structure and capabilities of the human brain. “The brain is the most complicated machine of which we are aware on this planet,” says Simon Alford, PhD, department head and the Mary & Raymond Nester Sweeney Professor of Basic Sciences. “In the last 30 years, we’ve discovered more about the brain than mankind had previously learned throughout history, and we’re still just scratching the surface.” Alford and others in his department, such as Scott Brady, PhD, are expanding the fundamental knowledge of how the brain works—necessary to address the diseases that impact it—through research that bridges cellular biology and neuroscience. Their research focuses on the mechanisms and effects of synaptic plasticity, meaning changes that occur at synapses, the junc- MAXIMIZING BRAIN HEALTH tions between neurons that allow them to communicate. “We need to ILLINOIS MEDICINE | 17 understand the basic science of department are tackling the elusive cure for Alzheimer’s disease. LaDu how the brain works in order has developed animal models that accelerate degeneration in mice to fully address the diseases brains, focusing on the properties and interactions between two pro- that affect brain health,” Al- teins that are genetically, pathologically and biochemically linked to ford says. Alzheimer’s disease: amyloid-β (Aβ) and apolipoprotein E (apoE). The Research in the anatomy models also provide a testing ground for compounds that may prevent and cell biology labs already or even reverse the damage and provide insight into the gender-related has yielded discoveries that risk of developing the disease. could change the course of Other researchers in anatomy and cell biology, such as Sarah Lutz, some of the most devastating PhD, and Leon Tai, PhD, are investigating whether inflammation in degenerative diseases in future the blood-brain barrier might be involved in a number of neurodegen- clinical applications. For erative diseases of the mind; while Kuei Tseng, MD, PhD, is collabo- example, Ernesto Bongarzone, rating with colleagues in psychiatry to assess whether cannabinoids PhD, and Maria Givogri, PhD, comprise one of only a dozen research modify developmental changes in rat models as they go through groups in the nation to receive a 2017 Catalyst Award from the Dr. adolescence. Ralph and Marian Falk Medical Research Trust Awards program. “In our department, we’re working with a range of disciplines as a The $300,000, one-year award will further their research on bridge between fundamental and clinical science,” says Alford. turning naturally occurring extracellular vesicles—tiny “bubbles” given off by a range of cell types—into targeted delivery vehicles for Neurology and rehabilitation: drugs to treat multiple sclerosis. The team is also working on a genet- Tackling brain disease with big data ic modification model for Krabbe disease, a disorder that destroys the protective coating (myelin) of nerve cells in the brain and throughout TO STIMULATE INNOVATIVE RESEARCH and help scientists uncover the nervous system. “Bongarzone is using animal models to inject a new cures for diseases like epilepsy, ALS (Lou Gehrig’s disease) and virus that carries a replacement gene for the faulty gene in the brain,” brain tumors, the neurology and rehabilitation department last year says Alford. “The process temporarily cures Krabbe disease in ani- launched the NeuroRepository, a one-of-a-kind human brain tissue mals and holds hope for the future.” bank and research database. Researchers such as Mary Jo LaDu, PhD, and others in the Located at the NeuroPsychiatric Institute, which is celebrating its 75th anniversary this year, the NeuroRepository houses tissue specimens linked to clinical, radiological, physiological, histological and molecular/genomic data—“big data” that requires advanced computing hardware and software. “The tissue plus its data set provide a basis for discovery not available through any other regular tissue bank or data warehouse and is available not only to Illinois Medicine researchers, but also to those across the country,” says Jeffrey Loeb, MD, PhD, John S. Garvin Endowed Chair and head of neurology and rehabilitation. The NeuroRepository has already yielded some transformational insights. “Using MRI technology, we have a new way to see epilepsy in the human brain by identifying a unique metabolic signature that’s associated with the epileptic brain tissue, which causes seizures,” says Loeb. “One of the biggest challenges in epilepsy is in diagnosis. With this new biomarker, we should be able to detect very small regions of epileptic activity—smaller than a single square centimeter—and we can do it noninvasively.” Loeb and his colleagues also have used the NeuroRepository to uncover a new kind of micro- “The brain is the most complicated machine of which we lesion present in epilepsy. “Using mathematical models, we were are aware on this planet. In the last 30 years, we’ve able to predict and then confirm discovered more about the brain than mankind had the existence of the lesions, which previously learned throughout history, and we’re still just will help us understand why some scratching the surface.” areas of the brain become epileptic and some don’t,” says Loeb. — Simon Alford, department head and the The department is working to Mary & Raymond Nester Sweeney Professor of Basic Sciences turn newfound knowledge about

18 | SPRING 2018 .,,

human brain disorders into state-of-the-art technology patient treatments. For example, to patients with acute and Michael Carrithers, MD, PhD, severe emergencies such as and Charles Abrams, MD, PhD, strokes, aneurysms, brain are tackling treatment advances tumors and head injuries, for multiple sclerosis and nerve as well as those suffering and muscle diseases. “We also from degenerative spinal have a drug in development that disease and chronic pain. we’re hoping can slow neurode- “We are one of very generation in ALS,” says Loeb. few centers in the world “Fei Song (MD, PhD) is conduct- that is capable of per- ing tests in animal models, and forming certain therapies “The University of Illinois we’re hoping to take the drug to related to diseases of the clinical trials.” blood vessels, such as aneurysms and vascular malformation of is the go-to place for For patients afflicted with the brain,” says Fady Charbel, MD, department head and the Dr. patients with complex brain tumors, the University Richard L. Fruin and Gertrude W. Fruin Professor of Neurosurgery. brain disorders. We are of Illinois Brain Tumor Center, For example, Charbel collaborated with the university’s engineer- making discoveries we didn’t headed by Kelly Nicholas, MD, ing department to develop the Noninvasive Optimal Vascular PhD, offers treatment that may Analysis (NOVA), a software program that quantitatively measures dream of because we’re able not be available to patients blood flow to the brain using standard MRI equipment without to generate and test new anywhere else. “Every patient any contrast. hypotheses here, most of deserves to be in a clinical trial,” In a landmark, eight-year, National Institutes of Health- which come from our clinical says Loeb. “Our drug studies are funded, multi-site study called Veritas, for which the COM served programs, which are second UIC-specific and are coupled as the lead site, NOVA was used to determine which patients are with the highest level of and at risk for recurrent stroke in the vertebrobasilar system, which to none.” most compassionate patient supports the critical functions of the brain stem and cerebellum.

— Jeffrey Loeb, John S. Garvin care.” “Prior to Veritas, treatment was determined by a picture of a nar- Endowed Chair and head of In addition to research rowed blood vessel,” says Charbel. “Using NOVA, we are able to neurology and rehabilitation and treatment, the neurology determine which patients need department is also working to treatment. Patients who help patients better understand had low blood flow accord- and monitor diseases, such as epilepsy, through education. Loeb and ing to our algorithm had his colleagues, such as Dilip Pandey, MD, PhD, have pioneered a self- 5.5 times the risk of stroke. management education program called Personalized Internet-Assisted We were able to develop Underserved Self-management of Epilepsy (PAUSE to Learn About Your precise therapies to suit Epilepsy). patient needs.” “Epilepsy is a very complex disease, and some of the roadblocks for To measure blood flow patients of different socio-educational backgrounds are lack of accessi- during surgery, Charbel bility to care and information overload,” says Loeb. “Through a CDC- also has developed Flow funded grant, we are able to send computer tablets home with patients Assisted Surgical Technol- so they can review information on managing their epilepsy at their own ogy, a probe that is now pace, even if they don’t have Internet access.” part of the lexicon of PAUSE is customized in an office visit for each patient’s learning neurosurgery around the ““We are one of very few needs. Tablets also have a real-time video conferencing capability with world. Next, the depart- centers in the world that an educator to help patients reduce emergency room visits. ment is looking to apply the “The University of Illinois is the go-to place for patients with data from Veritas to new is capable of performing complex brain disorders,” says Loeb. “We are making discoveries we therapeutic devices. “We certain therapies related didn’t dream of because we’re able to generate and test new hypotheses are working to launch a to diseases of the blood here, most of which come from our clinical programs, which are second new clinical trial where we vessels, such as aneurysms to none.” will do everything inside and vascular malformation of the MRI, treating patients Neurosurgery: just enough to optimize the the brain.” A data-driven approach to care blood flow,” says Charbel. — Fady Charbel, department One faculty member head and the Dr. Richard L. AS AN IMPORTANT THERAPEUTIC ARM of the neurosciences, Illinois actively involved in those Fruin and Gertrude W. Fruin Medicine’s internationally known department of neurosurgery provides clinical trials is Sepideh Professor of Neurosurgery

ILLINOIS MEDICINE | 19 Amin-Hanjani, MD. “As the department’s co-clinical director and Other physician scientists residency program director, Sepideh has also been working on such as Olusola Ajilore, MD, guidelines for stroke at a national level,” says Charbel. PhD, and Alex Leow, MD, In fact, the University of Illinois Hospital & Health Sciences PhD (see p. 10), are using System has been designated by The Joint Commission and the connectomics, mathematical American Heart Association/American Stroke Association as a models to study connectivity Comprehensive Stroke Center, a recognition of its status as an in- in the brain, while Scott dustry leader in setting the national agenda for highly specialized Langenecker, PhD, is a stroke care. cognitive neuroscientist Illinois Medicine is also taking a quantitative approach to working to understand the aneurysms. “Just as we did with Veritas, we are working with mechanisms of depression and engineering at UIC and other universities, studying the walls of mood disorders. To support the estimated aneurysms to see what makes one more prone to rupture than an- “We are in a unique other,” says Charbel, who has personally treated more than 6,000 14.8 million U.S. adults affected position of training the aneurysms. “We then want to investigate what we can develop to by depression, the University of help us determine a rupture before it occurs.” next generation and are Illinois Center for Depression In addition, the department is working on strategies to use at the cutting edge of and Resilience (UICDR) was magnetically guided nanoparticles that deliver therapeutic agents conducting research launched in 2014. This multi- disciplinary initiative, modeled directly to tumors in the spinal cord, without patients suffering that brings meaningful from systemic toxicity. Such work is spearheaded by Ankit Mehta, after the collaborative approach change into the lives of MD, who also has been screening for depression with spine dis- of the National Cancer Institute, ease, investigating how it could affect patient outcomes. patients that are often brings together clinicians, edu- “We believe in a data-driven approach to care and are never underserved. We’re tackling cators and researchers in a team satisfied with the way things are today,” says Charbel. “We can brain health as it’s never science approach to address always do better tomorrow.” mental illness and disease. been done before.” The UICDR is part of the National Network of Depression Psychiatry: At the forefront — Anand Kumar, MD, of addressing mental health needs department head and the Centers, a nonprofit research Lizzie Gilman Professor consortium located in 26 sites ILLINOIS MEDICINE’S DEPARTMENT OF PSYCHIATRY is of Psychiatry across the country. “We are the uniquely positioned as the top-ranked NIH-funded department only NNDC site in Chicago of its kind in the Chicago area to pursue its quest for brain health focused on the clinical and advancements. And the need has never been greater. According to research aspects of mood disor- the National Alliance on Mental Health, approximately one in five ders,” says Kumar. adults experiences mental illness in a given year. The collaborative work of the UICDR is already showing promise. “Our Alcohol Research Center, directed by Subhash Pandey For example, Phan is leading the effort for Repetitive Transcranial [PhD] is the only alcohol center funded by the NIH in Illinois Magnetic Stimulation, a noninvasive form of brain stimulation that and the only one to focus on epigenetics, the field of molecular uses magnetic coils to treat depression. “RTMS provides another science that looks at the connection between environmental modality for patients who have not responded well to other types of stressors and molecular mechanisms of gene expression in the treatment,” says Kumar. brain,” says Anand Kumar, Whether through translational research or clinically, the depart- MD, department head and ment is committed to delivering new mental health strategies and Lizzie Gilman Professor of treatments across the human lifespan. For example, the Institute Psychiatry. for Juvenile Research, headed by Marc Atkins, PhD, is focused on The department is also identifying, preventing and treating behavioral, social or emotional using neuroimaging tech- difficulties among children and adolescents. niques, such as functional On a national level, the department is aligned with The Kennedy and structural MRIs, to Forum, a public interest organization that fights the stigma of mental understand brain function, illness, but it also has a pervasive local presence. “We are proud of connectivity and neural our strong commitment to improving mental health in underserved networks. For example, K. communities,” says Kumar. Luan Phan, MD and Heide “At Illinois Medicine, we have integrated research, patient care Klumpp, PhD, are using the and education,” he says. “We are in a unique position of training the technology to measure brain next generation and are at the cutting edge of conducting research changes that occur in post-traumatic brain disorders and anxiety, that brings meaningful change into the lives of patients that are particularly in response to treatment through medication or cog- often underserved. We’re tackling brain health as it’s never been nitive behavioral therapy. done before.” B

20 | SPRING 2018 teaching leaders

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EDUCATING MEDICAL LEADERS COM excels as an incubator of leaders in medical education

Better teaching and better learning go hand in hand, perhaps never more so than when educating future physicians to be capable of delivering the best of care. The College of Medicine Chicago’s department of medical education has long set itself apart by training prominent influencers in a field responsible for developing competent doctors able to function in an ever-evolving health care landscape. By offering graduate and undergraduate programs uniquely designed to enhance the leadership and scholarship skills of health professionals and promote lifelong learning, the college’s department of medical education and its co-curricular partners have made a Bprofound impact in shaping many of today’s medical education leaders—around the world and close to home.

ILLINOIS MEDICINE | 21 The Department of Medical Education remains the oldest department in the U.S. dedicated to the study and improvement of medical education.

North of the border and community sites and develop models of interprofessional education. He credits his training at UIC for his upward career “GOOD DOCTORS AREN’T AUTOMATICALLY good teachers,” trajectory. “The brand of the master’s program gave me instant says Salvatore Spadafora, MD, MHPE ’01, a graduate of the credibility as a medical educator,” he says. “While I worked hard, COM’s master of health professions education (MHPE) program no doubt my rigorous training afforded me many opportunities designed to develop educational leaders. Currently the vice dean that have put me in the position I am in today.” of postgraduate medical education and continuing professional development at the University of Toronto, Spadafora came to this Ensuring quality realization as a young anesthesiology resident at the University of education Western Ontario in his native Canada. Although his specialty training would prepare him well for ACHIEVING AND MAINTAINING clinical practice, he felt his own ACCREDITATION status plays a residency experience cried out significant role in motivating medical for more structure in terms of colleges to meet quality standards. formal teaching training. “It Yet the precise impact of accreditation could be hit or miss, what you on the quality of medical education learned,” he recalls of his time remained relatively amorphous until as a trainee. “While the ‘see Danielle Blouin, MD, MHPE ’03, one, do one, teach one’ method PhD ’16, professor in the Faculty of is still applicable in medicine, Health Sciences and in the Faculty of 2015 you can also get formal training Education at Queen’s University in Executive to become a better teacher and Salvatore Spadafora Kingston, Ontario, Canada, made it Masters of improve on what you see is the core of her research. lacking in medical education.” The first graduate of COM’s Healthcare With that in mind, Spadafora enrolled in COM’s master’s collaborative doctoral program in Administration program as soon as he completed residency training in 1995. He health professions education and soon acquired the modern educational methodology tools he was curriculum studies with the University (EMHA) program seeking to become a better medical educator. Thinking he would of Illinois College of Education, established help enhance the education system on a sporadic basis while this Canadian emergency medicine providing care as a small-town doctor, he physician wrote her thesis on the at UIC quickly found his COM education and the influence of accreditation processes on MHPE’s global reputation propelling him the culture of quality improvement in toward a more influential leadership path. Canadian medical schools. Spadafora started down this road by “There was no scholarly work serving as program director of Western on the subject when I started my graduate studies in 2013,” says Ontario’s anesthesia and family-medicine Blouin, who at the time had just taken a post as assistant secretary anesthesia residency programs in 2002 and of the Committee for the Accreditation of Canadian Medical then, six years later, becoming associate Schools and the Committee on Accreditation of Continuing dean of postgraduate medical education for Medical Education in Canada. “It gave me a niche.” the university’s Schulich School of Medicine In 2014, Blouin was tapped to head both key organizations 1959 and Dentistry. charged with ensuring the quality Today, as a leading medical educator and integrity of medical school George E. Miller, at one of Canada’s oldest and most programs across Canada via MD, founded esteemed medical schools, Spadafora rigorous monitoring and review. oversees the education and training of In addition to her leadership COM Office 3,600 medical residents and fellows. With responsibilities, she continues to of Research the added responsibility and oversight of build on the research she launched continuing medical education conferences at the COM. “I am still writing in Medical and programs, he also ensures the lifelong papers based on the novel ideas Education (which education of some 42,000 additional generated during my PhD studies,” learners attracted to the University of Danielle Blouin Blouin says. A globally renowned later became Toronto’s CME offerings. scholar, she remains focused on the department Applying his knowledge from the program evaluation as it relates to accreditation. Her current work of medical COM to benefit patients in Canada’s involves defining and assessing markers of quality in medical single-payer system, Spadafora has education to better connect the dots between accreditation status education) worked to integrate education in urban and the ability to educate high-performing future physicians.

22 | SPRING 2018 The Department of Medical Education remains the oldest department in the U.S. dedicated to the study and improvement of medical education.

Blouin remains grateful for “The EMHA program exposed me to the many challenges the leadership and scholarship that frustrate and discourage practitioners in the delivery of skills she honed through care, especially to the economically disadvantaged,” says Girotti. the department of medical “Tweaks to our curriculum could include the concept and education’s MHPE and PhD importance of physician leadership in working more effectively programs. “UIC opened my within organizations and overcoming obstacles to better serve the eyes to new horizons in medical underserved.” education,” she says. “My initial goal was only to become Nurturing future physician leaders a better teacher, but I soon PREPARING TOMORROW’S PHYSICIANS means educating found myself part of a greater them for a future of nonstop change. medical education community 2017 “The current health care landscape is chaotic at best,” says that I wanted to become more Clinical Michele Mariscalco, MD, EMHA involved in.” Executive ’16, associate dean for systems- Close to home based practice at the COM and Medicine assistant vice chancellor for health AFTER 36 YEARS AT THE (CEMED) sciences academic affairs. “How COLLEGE OF MEDICINE, do we best raise our students improving the education of program to find their place as medical medical students remains launched professionals and clinician leaders energizing for Jorge Girotti, in a constantly changing health PhD ’90, EMHA ’17, an assistant at COM care world?” professor in the department Michele Mariscalco To that end, the COM of medical education, director launched the Clinician Executive of the Hispanic Center of Medicine program (CEMED) Excellence and associate dean for admissions and special last fall to provide budding physician leaders with the insights curricular programs. After completing the University of Illinois at required to navigate the complex organizational and health policy Chicago’s Executive Master of Healthcare Administration program changes that often impact delivery of care. in December 2017, he plans to use this most recent training to A key faculty member of the new four-year program enhance education at the COM. for students in Chicago, Peoria “The program illuminated for me the delivery side of health and Rockford, Mariscalco became care and what our graduates face beyond clinical competency, passionate about instilling business from dealing with health policy issues to organizational and savvy in medical students after her leadership challenges,” says Girotti. “It’s prompted me to think own experience completing the EMHA about what we can do earlier in program. Earning the degree gave her a the educational pipeline to better much greater understanding for the need prepare our students.” to nurture clinician leaders at the outset UIC added the EMHA of their medical careers. program to its educational “Clinician leadership comes in offerings in 2015, and at its genesis many forms,” she says. “From managing the program was established as peers in a small group practice to a collaborative effort between directing a clinical service in a large 433 the College of Medicine and the health enterprise, physicians can’t School of Public Health to expand think of themselves as widgets in a big Number of leadership and knowledge of the worker wheel. They must learn to take Masters Jorge Girotti business of health systems. Similar ownership. That’s what we can impart to of Health to an executive MBA program, but our students early on.” broader in scope and intention, A seasoned educator, Mariscalco Professions EMHA integrates the clinical and administrative aspects of embraced the chance to acquire new Education managing and working within healthcare organizations. knowledge via the EMHA program Girotti sees several opportunities to incorporate what he to enrich her career. In fact, she was alumni learned into the COM curriculum. For example, as director of one of a half-dozen COM leaders who the college’s Urban Medicine program, Girotti believes students participated in the program’s first cohort could benefit from a deeper understanding of the socioeconomic of students. “Lifelong learning always provides additional insights forces that influence the ability of urban health systems to address that you can choose to use or expand upon if you need more. It’s healthcare disparities. what education is about, after all.”

ILLINOIS MEDICINE | 23 gala & campaign launch

by Ed Finkel

GALA IGNITES COM FUNDRAISING CAMPAIGN Celebration sparks inspired in support of education, research, medical care that happens here

he annual Illinois Medicine Gala, held in the University of Illinois Foundation. for coming to “celebrate the success “Philanthropy plays an important role and impact of the crown jewel of October at The Geraghty in Chicago, in this pursuit and the achievement of UIC—the College of Medicine—and to recognized major donors with the College our bold vision for the future of medical start the launching activities of a new education and healthcare.” university-wide fundraising campaign.” of Medicine’s William W. Root Society, as Robert Barish, MD, MBA, vice Amiridis recalled the Greek philosopher well as the recipients of the 2017 Illinois chancellor for health affairs, welcomed Plutarch, who once declared that “a TMedicine Awards in five categories. the several hundred alumni, faculty, mind is not a vessel to be filled but a students and friends of the college fire to be kindled.” Added Amiridis, But what truly lit the spark at already had been raised by mid-October. in attendance. “UIC, UI Health and “Here at UIC, we celebrate the flame this year’s gala was the College of “The campaign for medicine at the College of Medicine stand on the inside each one of us; the spark that Medicine’s launch of its part in the UIC will firmly distinguish our college threshold of great achievement in is determined to reach excellence not campus-wide University of Illinois at among the premier destinations for advanced medical education models, bound by circumstance.” Chicago IGNITE fundraising campaign. medical education in the world and biomedical discovery and community- The IGNITE campaign will help The multi-year effort to raise a goal of elevate our already stellar reputation based patient care,” he said. “The work UIC and the COM light the spark of $280 million for the COM will support in research and community- that happens here inspires careers and their ambitious agendas, Amiridis said. scholarships, endowed chairs, faculty centric healthcare delivery to new ignites new futures—for our students This includes the threefold mission “to research, impassioned medical care, heights,” said Stephanie Grinage, and patients alike.” make UIC’s educational experience technological innovation and more. associate vice chancellor for medical UIC Chancellor Michael accessible to the next generation Nearly half of the goal, $125 million, advancement and vice president of Amiridis, PhD, thanked attendees of global citizens; build and expand

24 | SPRING 2018 1 2 GALA IGNITES COM FUNDRAISING CAMPAIGN Celebration sparks inspired in support of education, research, medical care that happens here

upon the work and reputation of our to the COM’s scholarship fund and people are all mentors to us. This outstanding faculty; and transform plans to give more “when the time opportunity is just unbelievable.” our neighborhoods by tackling the comes.” Student Anna Brzezinski, a toughest challenges that face our Rosa Berardi, program officer member of the Innovation Medicine 3 communities,” he said. at The Coleman Foundation, said the Program, expressed her gratitude Researchers at the COM have COM is one of 10 medical centers in a toward the COM’s supporters and developed life-saving transplant collaborative her institution funds that’s admiration for Illinois Medicine surgery techniques and HIV drugs, looking at redesigning the process and awardees. “The people we will honor brought national awareness to the reformulating the services provided to tonight demonstrate the iconic hazards of BPA, increased access to those who have recently received the qualities of our college and the healthy foods in urban areas, led the devastating diagnosis that they have impact that each of us can have on world in high-performance computer cancer. the future of medicine,” she said. visualization and validated the first cure Coleman has provided support for Those receiving Illinois Medicine for sickle cell disease, Amiridis said. In the psychosocial aspects of oncology awards for 2017 (see pages 28-31

process are the development of cures for the past 25 years and has been for profiles) were:Emil J. Freireich 4 for diabetes and Alzheimer’s disease. promulgating principles and ideas ’47, MD ’49, Pioneer in Medicine; “And at the core of our mission is aligned with recommendations from the Terry Mason, MD ’78, Distinguished seeking out new ways to reduce and National Academy of Medicine, Berardi Alumnus; Janet Lin, MD ’99, eliminate health disparities,” he said. said. “It’s a process improvement MPH ’04, Emerging Innovator; Gala attendees all had their own project to look at how services are Bruce Gillis ’69, MD ’74, MPH, reasons for supporting the College of delivered,” she said. “University Innovator of Today; and Marion and Medicine and feeling their flames lit by of Illinois [COM] is putting these James Grant ’52, MD ’54, Spirit its mission. For Bruno Pasquinelli, processes in place.” of Medicine. a Root Society donor, the spark was Student Drew Ormseth, Inducted as lifetime members kindled after he needed a doctor and who serves as student alumni in the Root Society, for cumulative was referred to UI Health. “They have representative, said he and his contributions of at least $100,000, were probably the best doctors in the world classmates found the Gala to be an Dr. Robert and Marika Panton, and here,” he said. “The doctors here have outstanding opportunity to meet and Peoria Regional Dean Dr. Sara Rusch a passion.” He gives to the school hear from alumni, which had taken and Dr. Thomas Cusack. Inducted and urges others to do so, to support him away from the day-to-day grind of as annual Root Society members, faculty research in areas like robotic medical school and reminded him what for contributions of at least $10,000 5 surgery. ignited his spark to attend the COM. during the current fiscal year, were Vice Alumna Eslyn Garb, Pharm “In medical school, you can Chancellor Dr. Robert Barish and ’81, MD ’87, built her bond with an fall into a hole of studying and lose Jenny Barish, Dr. Raymond Curry institution that has a deep commitment track of why you wanted to come in and Dr. Kristi Kirschner, Susan to admit people of all ethnic groups the first place,” he said. “The videos Donahue, Dr. Thomas and Elaine and socioeconomic statuses. “They they showed were very inspirational Layden, Dr. Richard and Luci took me in. I was not rich. I was hard- and reminded me why I wanted to go Nora, Dr. Mark Rosenblatt and working,” she said. “They educated into medicine. Getting this alumni- Jean Tsai, and Mary Bert and me, and I am grateful.” She has given to-student interaction is huge. These Dr. Richard Wolf.

OPPOSITE PAGE: UIC Chancellor Michael Amiridis (center, at podium) welcomes COM alumni, faculty, students and friends to the launch of the college’s portion of IGNITE: The Campaign for UIC. He’s joined by (at left) Robert Barish, vice chancellor for health affairs, and (at right) 6 Stephanie Grinage, associate dean for development, and Dimitri Azar, who recently resigned as executive dean.

RIGHT, TOP TO BOTTOM: During the COM Gala and Campaign Launch event: 1 Professor of Medicine Subhash Kukreja congratulates Distinguished Alumnus Award recipient Terry Mason; 2 attendees enjoy the celebration• following the campaign launch, which highlighted the COM’s programs and achievements in Urban Medicine,• Rural Medicine, Global Medicine and Healthy Communities; 3 Robert Barish, vice chancellor of health at UIC, presents the Innovator of Today Award to Bruce Gillis; 4 Dean Emeritus Joseph Flaherty •(center) shares smiles with Root Society members Bruno and Sallie Pasquinelli; 5 Spirit of Medicine Award winner• Marion Grant (center, pink dress) joins then-Executive Dean Dimitri Azar (left) and a group of current medical• students; 6 an attendee test-drives one of the virtual reality innovations used in educational modules at the COM Peoria; 7 department of medicine• faculty members and their spouses celebrating a new future with the IGNITE campaign include (left to right) professor •David Perkins, Anil Oroskar, Asha Oroskar, department of medicine head Patricia Finn, Angela Layden, and associate professor Brian Layden.

ILLINOIS MEDICINE | 31

7 reunion

by Dan Baron

REUNION 2017: Alumni Reminisce, Reflect on COM’s Evolution

S THEY GATHERED TO CELEBRATE and reminisce last October, members of the 50th Reunion class were especially struck with the updates to the COM. “One of the things that has always impressed me about UIC is how it has integrated classroom learning and patient care early in the medical curriculum,” said Melissa Dianovsky- Hoeppner, MD ’88, a pediatrician at Pediatric Associates in ArlingtonA Heights, Illinois. “Now I’m also seeing even more student-to-student collaboration as part of team- based learning.” Olga Wasile, MD ’92, traveled to the reunion from Chugiak, Alaska, where she has a family practice. Wasile was a nurse and had four children before she started medical school at the COM; she also has experience in the Army Nurse Corps and the Air Force Medical Corps. “I’ve been kind of busy,” said Wasile, who is also a grandmother, with a smile. While walking through the College of Medicine’s West Tower en route to an Illinois Med Talk presentation, she said the medical buildings and facilities are “a lot brighter than they were. They are bright and modern.” Stephen Aprill, MD ’67, a longtime specialist in internal medicine and oncology in Washington state who now lives in Santa Monica, California, attended the event with his sister and daughter. Aprill reflected on his time at the COM and noted how it has changed. “The school did well by me,” Aprill said. “Now I am struck by the facilities and the growth of this place,” he added, noting that UI Health, the university’s hospital, hadn’t even opened when he graduated from medical school. “It’s really amazing.” Ethelyn Williams-Neal, MD ’67, is a pediatrician in Memphis who also teaches in clinical environments at Methodist Hospitals of Memphis. Moments before the Illinois Med Talk presentations during the reunion, she marveled at a classroom with more than a dozen large LCD screens that broadcast educational content—an example of advanced technology that has become an integral part of how today’s students learn. “I have fond memories of UIC, and the medical education I got here has served me well,” Williams-Neal said, adding that she was also pleased to see “how diverse the school is these days.” Williams-Neal, who has devoted much of her career to serving children in the Memphis area, also noted the emphasis the COM places on serving underserved communities and the belief that health care is for all. “I’ve been in this field for 50 years now,” she said, “and I still strongly believe that health care should be a right.”

26 | SPRING 2018 27

| illinois med talks in to ILLINOIS MEDICINE Pier Giulianotti Jennifer Lim Curry Raymond Active learning in medical education MD, senior associate Raymond Curry, talked dean for educational affairs, about how the new Illinois Medicine several trends curriculum reflects medical education, including a greater emphasis on team-based active learning, a longitudinal, developmental approach student assessment, and the integration of clinical perspectives and experience of medicine and medical medical school. A professor throughout types of courses education, Curry also discussed the different students will take, including a new format of block courses, and 12). John Groth, (see p. courses that focus on wellness and resilience augmented Curry’s of clinical pathology, MD, assistant professor thoughts by noting how the new curriculum has been constructed to want “We In the end, he said, focused and less redundant.” be “more about critical thinkers. Curriculum change is really to help create active learning.” surgeryAdvances in robotic Pier Giulianotti, MD, a pioneer in the field, on the a passionate presentation delivered in general surgery. potential of robotics growing at the COM can “go beyond our Researchers limits,” said Giulianotti, chief of the division of surgery at general, minimally invasive and robotic than 3,000 UI Health, who has performed more minimally invasive surgeries and 2,000 robot- he assisted surgeries. During his presentation, surgery and described how of robotic emphasized the precision array of potential applications for surgery has an increasing robotic kidneys and many other organs. liver, surgeries on the pancreas, surgery is a cultural “Supporting the development of robotics of the investment,” said Giulianotti, who serves as honorary president about achieving what really Clinical Robotic Surgery Association. “It’s be able to do otherwise.” we wouldn’t ILLINOIS MED TALKS FEATURED CURRENT COM FACULTY as they as they FACULTY CURRENT COM FEATURED ILLINOIS MED TALKS to education and innovative approaches showcased the inspired presentations that continue to happen on campus. The clinical care of modern insight into applications held on October 13 provided in in ophthalmology and surgery, technology to novel therapies of medical education and its application addition to the new model curricular update. to the COM’s research retinal on Reflections service of retina Jennifer Lim, MD, director the Sweeney Society at UI Health, delivered and of Distinguished Faculty Presentation visuals that demonstrated how she shared has worked to halt the impact of age-related macular degeneration and various other diseases and to potentially blinding retinal She emphasized her visual acuity. improve inspiring vision, goals of “restoring career-long the story of one learning and passing on knowledge.” Lim related him with she provided patient who gained measurable eyesight after the once legally blind man to see shapes implant that allowed a retinal nice to this patient said to a grandchild, ‘It’s and light. “I remember thus she said. Reflecting on her career tall,’” pretty see that you’re ride.” a great been she exclaimed, “It’s far, Illinois Med Talks Talks Med Illinois LifelongRekindle Learning pioneer in medicine award

by Richard Asa

A TRUE G PIONEER IN THE CURE FOR CANCER Emil J Freireich ’47, MD ’49

28 | SPRING 2018 pioneer in medicine GROWING UP IN CHICAGO’S HUMBOLDT PARK neighborhood offered plenty of a paper on that subject. “It’s a citation classic.” struggles and challenges for Emil J Freireich, but it also built resilience. Through By 1958, Freireich and colleagues proved they could cure childhood leukemia persistence and dedication to his education, Freireich persevered to become one in many cases by combining four drugs. of the pioneers of cancer treatment at a time when the multi-drug approach he But this development wasn’t without controversy. Prominent researchers at took was ridiculed, and even condemned. the time discredited the approach, particularly because children got sicker from the For all of the groundbreaking research he conducted and treatment he drugs’ side effects before they got better. The grit Freireich developed in childhood provided, Freireich ’47, MD ’49, was honored with the 2017 Pioneer in served him well. Eventually his critics would come to understand the benefits of GMedicine award at the Illinois Medicine Gala in October (see p. 24). this treatment. And today, the therapies he developed for cancer treatment are The son of Hungarian immigrants who ran a restaurant but lost it to the Great standard practice. Depression, Freireich was just 2 when his father died. He rarely saw his mother, By the mid-1960s, Freireich was enticed to join the nascent MD Anderson who worked grueling hours at a millinery workshop. Cancer Center, which at the time was a tertiary hospital with 100 beds and no “When you grow up on the streets, all you want to do is survive,” he says. research facility. He was at first hesitant to leave the well-established National Freireich was a diligent student, however, and he even graduated high school Cancer Institute. But once he and a handful of prominent researchers came to a year early. He hadn’t thought past a career as a typist or secretary until a physics Houston, the center was on its way to becoming a top cancer treatment and teacher encouraged him to attend the University of Illinois. research mecca in the U.S. After completing his bachelor’s degree, he returned to Chicago to attend Today, nearly all successful cancer chemotherapy follows his approach of medical school at the COM, as part of a class of 188 students at a time when only multiple drugs being used together. few applicants were admitted. At 91, Freireich looks back on the roots of his medical career with fondness “The College of Medicine was the most exciting period of my life,” Freireich and gratitude. says. “I did very well in the basic sciences, and when I got to the clinical sciences, I “Well, I don’t have any comparison. I only went to one school,” he says. really enjoyed it.” “But the University of Illinois has created a whole generation of scholars in all As a medical student, he pursued a rotation at Cook County Hospital, the disciplines. I mean it’s just a great institution, a public institution that has adjacent to the medical school. Freireich’s first rotation was with tuberculosis transformed the nation in a way. Every state has institutions that do that. But Illinois patients, at a time when the disease was rampant. He then rotated to infectious is a star in my universe. disease. He says both were “horrible” for the impact they had on patients. “It made me a doctor,” he adds. “I could have gone to a hundred medical Freireich’s training continued at Presbyterian Hospital, where he became the schools, probably, and I don’t know if the result would be the same. But my chief resident. That was where he met his wife, Haroldine, who was the head nurse experiences at County and Presbyterian made me the investigator who went to at the time. Washington to cure leukemia. After his formal training, Freireich’s path took him to Boston College, where “They transformed me from a typist to a physician who has cured patients he published a significant paper early in his career, and then he was hired by the with cancer. What else can a university expect? That’s great.” National Cancer Institute in Washington, where he was tasked with “finding a cure Freireich saw his last patients in 2015, but he continues to work on research for leukemia.” By then, he had treated leukemia and was well-versed in drugs that to advance cancer treatment including stem cell transplantation and maintains were being used. In 1955, there were three drugs shown to induce temporary contact with doctors and trainees on the staff. remissions in children with acute lymphoblastic leukemia. A fourth was added a Freireich is modest about the Pioneer in Medicine award, saying that he is few years later. grateful, but that he believes the College’s importance to the community and the From day one at the cancer institute, Freireich was in charge of a ward full state outweighs any individual recognition he could achieve. of children who had leukemia. He soon observed that the greatest obstacle to “Being a pioneer in anything is a real honor,” Freireich says. “It means that successful treatment was hemorrhage. The disease produced horrific symptoms you have the ability to break through the darkness and create light. And what at that time; kids would bleed from their ears, mouth and nose. Desperate parents the medical school does is gives you the tools to peek into the darkness and to were willing to try new treatments. discover new things.” Freireich began to concentrate on how to stop the hemorrhaging and noted His message to prospective students? Medicine is humanity’s “highest calling. a direct relationship between the concentration of platelets and the possibility If you can become a physician, you have the privilege of extending life and relieving of bleeding. The higher the platelet count, the more likely there would be active pain and suffering. And that’s a very high calling,” Freireich says. “I’m excited to be bleeding. a physician, and I think that academic medical communities are a major part of the “Platelets were obviously important,” Freireich says. He and others published culture of any advanced society.”

Emil J Freireich ’47, MD ’49 pioneer in medicineILLINOIS MEDICINE | 29 illinois medicine awards

by Carla Beecher

SPIRITAWARD OF MEDICINE INNOVATORAWARD OF TODAY

James and Marion Grant Bruce Gillis BUILDING SIDE BY SIDE FIGURING OUT

HE LATE JAMES “DOC” GRANT ’52, MD ’54, and FIBROMYALGIA his wife, Marion, spent their lives finding new and better ways to help those in need. Their legacy continues RUCE GILLIS ’69, MD ’74, MPH, credits his mother to fuel the passion of today’s students by supporting for pointing him on the path to become a physician: the mission of the College of Medicine and student She wanted her son to be a doctor. He became that achievement. and much more as a research scientist, innovator and “He embodied the Spirit of Medicine Award with entrepreneur. This diligent practice and his unending concern for and devotion to Honored with the 2017 Innovator of Today Award, patients,” Marion Grant says of her late husband. “He helped them, Gillis founded Los Angeles-based EpicGenetics healed them and gave them hope.” BLaboratory Inc. in 2013, a biomedical company that developed a ® After serving as a Marine in World War II, James Grant completed conclusive fibromyalgia blood screening tool, the FM/a Test. Used an engineering degree at the Urbana campus of the University of worldwide, the test identifies immune system biomarkers unique to Illinois before starting a construction company. A few years later, he the disease. went on to pursue a career in medicine and never looked back. Always intellectually curious, Gillis finished his medical studies At the College of Medicine, Grant’s ability to communicate across at the College of Medicine in just three years, which allowed him to disciplines helped the hospital’s physicians work with engineers to spend an elective fourth year earning a master’s in public health at develop its first heart-lung machine in 1952. His diverse background, Harvard University, graduating from both institutions in 1974. combined with an entrepreneurial spirit, continued to enable Grant to As a student at the college, he recalls a faculty member build successful businesses throughout his career. predicting that his schooling would only supply him with about 10 After graduation, the Arizona native left the chill of Chicago percent of his medical knowledge. Reflecting, he says that “science winters for sunny San Diego where he opened the Pacific Beach has changed drastically over my career.” Medical Clinic in 1956. Grant met and married Marion, who has After medical school, he completed two medical residencies a background in education. By 1975, the couple sold his family- and two fellowships before embarking on a career that has seen him medicine practice in San Diego and moved to Newport Beach, use his entrepreneurial skills to start his own laboratory and hold a California, where Marion served as a high school principal. James prestigious faculty position at the University of California at then opened yet another successful family medicine practice in nearby Los Angeles. Irvine, which the couple sold in 1985. Gillis never thought he would be a prototypical physician. He With still more to accomplish and much too restless to retire, started out in academics and then began investigating disease the Grants began looking for their next venture. In 1990, when James processes that were still being evaluated. Grant was 70, they opened the country’s first two private, free- “I went into medicine to make a difference in the well-being of standing plasma centers in Texas. In addition to being one of the others and to advance science,” he says. largest plasma centers in the country at the time, Austin-Bio-Med Lab “For years, fibromyalgia was dismissed by the medical Inc. transformed the industry by shipping plasma worldwide. community as a bogus affliction. But I’m willing to poke and prod Although James Grant passed away in 2016 at the age of 96, into regions that not only have been ignored, but also looked down Marion continues his legacy by supporting students and medical upon. Our breakthrough has proven that this disease, which affects 6 education through philanthropic gifts. percent of the world’s population, is real.”

30 | illinoisSPRING 2018 medicine awards EMERGINGAWARD INNOVATOR DISTINGUISHEDAWARD ALUMNUS

Janet Lin Terry Mason LEADER IN PUBLIC HEALTH A PUBLIC FACE INITIATIVES FOR PUBLIC HEALTH

ANET LIN, MD ’99, MPH ’04, has orchestrated INCERE, KNOWLEDGEABLE AND AMBITIOUS, 2017 multidisciplinary teams of nurses, public health professionals, Distinguished Alumnus honoree Terry Mason, MD ’78, physicians, business leaders, engineers and others to effect who now leads the Cook County Department of Public change on a global scale in areas ranging from HIV diagnosis Health, became a doctor to address the health challenges to natural disaster field work. In recognition of her innovation of African-Americans. and drive, she received the 2017 College of Medicine The “death rates were higher and every indicator Emerging Innovator Award. was worse,” he says. “So I became a physician to improve J As an associate professor of emergency medicine, director of health Sthose numbers.” systems development in the Center for Global Health, and an affiliate After completing residencies in general surgery and urology and associate professor of community health sciences in the UIC School of working in private practice for a time, Mason began hosting “Doctor in Public Health, Lin has combined her interests to tackle societal medical the House” for Chicago’s WVON-FM in 1992. Believing that food was problems. Her insightfulness has pioneered a way to identify HIV during the most important driver of disease prevention, he founded the Center emergency room exams. And her innovative approach to natural-disaster for New Life in 1994 to treat chronic diseases with diet modification field work in other countries has given caregivers worldwide new ways to and exercise. “We could put a clinic on every corner in America, but it bridge health disparities. wouldn’t make much difference in outcomes,” Mason says. “Stroke, Until recently, Lin served as director of the International Emergency obesity and cancer are all driven by eating the right or the wrong foods.” Medicine and Global Health Fellowship at UIC, a post she held for 11 Ten years later, he launched Restart4Health, a weekly program that years. During that time, she worked extensively in Latin America, Africa met at various Chicago locations to provide information and support that and Asia to increase access to quality health care in areas with limited encouraged Chicagoans to adopt healthy eating and lifestyle habits. resources. Her ability to coordinate people, organizations and resources With a community-outreach background and a public voice from helped create a disaster-risk re-education training program for the people his radio show, he was tapped by Mayor Richard M. Daley in 2005 to of Haiti, who have been affected by hurricanes and earthquakes. become commissioner of the City of Chicago Department of Public Closer to home, Lin serves as the principal investigator of a Health, a role where he oversaw the city’s food protection, environmental program, Project HEAL, that works to increase HIV and hepatitis C permitting, immunization, and prevention efforts for communicable vaccination education, awareness, testing and linkage to care. diseases. With more than 1,200 employees and an annual budget “What she’s done with HIV screening in the emergency department of $200 million, Mason’s department also studied the root causes of is remarkable. It’s identified many people who did not know they were community health issues, including poverty, housing and transportation. HIV positive. Their lives will forever be affected in a very empowering Four years later he assumed the role of chief medical officer and way,” says Terry Vanden Hoek, MD, head of the department of chief operating officer for the Cook County Department of Public Health, emergency medicine. a post he holds today. Lin received the University’s Excellence in Teaching Award in 2013 “With a solid understanding of both the clinical delivery and the and served as chair of the International Section of the American College public health sides of health care, Dr. Mason has been the best choice of Emergency Physicians. She is currently the secretary/treasurer of the for these important roles,” says Jay Noren, MD, MPH, associate dean Illinois Chapter of the College of Emergency Physicians. for leadership development. illinois medicine awardsILLINOIS MEDICINE | 31 the ambassador network

by Michael Wesbecher

ENGAGED ALUMNI AMBASS ADORS COM Ambassador Network offers range of opportunities to stay involved

Last year, the COM launched the Get involved with the COM Ambassador Network today! There are several possibilities: Ambassador Network to provide a pathway for alumni engagement. Giving Reunion Class HOST Program Volunteers Volunteers back to the College of Medicine can take Are you celebrating a reunion year The HOST Program (Help Our Students many forms. Individuals can give of their soon? We’re already planning for the Travel—see volunteer profile on facing 2018 and 2019 College of Medicine page) is committed to helping match time, expertise, or network connections, Reunions. If your graduation year ends fourth-year medical students with in an 8, 3, 9 or 4, we want to hear alumni from across the United States or through philanthropic contributions. from you. You can help us connect as these students travel for residency with lost classmates, plan your reunion placement interviews. Our alumni The Ambassador Network has designed celebration or reach out to classmates volunteers provide students with a a framework for and let them know that you’re returning place to stay during the interview to campus for the celebration. process as well as additional advice members of the about the community and, if possible, the organization with which the student Illinois Medicine is interviewing. Even if you are unable community about to host a student in your home, there are options to meet students the available for dinner or provide guidance and counsel from afar via phone or email volunteer correspondence. For more information, opportunities email [email protected]. that support the mission and activities of the COM. Supporting the mission of our inspired medical education, innovative research program and insightful patient care is important as we continue to ignite a new future in medicine in the coming years. Individuals have given their time in support of departmental initiatives, lent their expertise as career mentors for current medical students, hosted students who travel to their locales for residency interviews, and helped to interview the next generation of medical students as they go through the admissions process. We encourage members of the Illinois Medicine community to get involved and stay connected, as the enthusiasm and support of our alumni and friends help to promote a sense of community and pride in the work that happens here.

32 | SPRING 2018 ENGAGED ALUMNI AMBASS ADORS COM Ambassador Network offers range of opportunities to stay involved

Get involved with the COM Ambassador Network today! There are several possibilities:

Event Sponsors Interview Volunteers This year, the COM will be planning The Office of Admissions is seeking events in suburban Chicago to volunteers to help interview medical Edward and Kathleen Chien bring together alumni, community school applicants and would partners and donors to discuss like your support. Volunteers will opportunities to advance the help faculty and staff to interview HOSTING AN ALUMNI- mission of the college, UIC and prospective candidates for the 2018- UI Health. Event sponsors play an 2019 academic year. Interviews STUDENT CONNECTION important role in making sure that take place on the Chicago campus we can host events in convenient but include prospective students Edward Chien ’84, MD ’88, MBA locations and are sustainably for all of our campuses. For more funded. information, contact the Office of RIGINALLY INSPIRED TO PURSUE MEDICINE by his mother, a Admissions at (312) 996-5635 or public health nurse, Edward Chien ’84, MD ’88, MBA, has [email protected]. been living and working in Cleveland for more than five years as the division director of maternal fetal medicine, fellowship director, professor of obstetrics/gynecology and study center director of the Eunice Kennedy Shriver, NICHD Maternal Fetal Medicine Unit Network at MetroHealth Medical Center, Case OWestern Reserve University. Two years ago, Chien became an active volunteer for the College of Medicine’s HOST Program (Help Our Students Travel). Designed to connect current medical students who are pursuing residency interviews across the country with COM alumni who live near students’ potential destinations, the HOST Program is celebrating another successful year of pairing students with alumni hosts who provided accommodations to visiting students, or insight into the programs with which they may be interviewing. Chien was moved to give back to the College of Medicine, and the HOST Program offered a unique way to stay connected and meet current medical students. He notes that although he interacts with medical students in his current position, the HOST Program “gave some insight and allowed me to see various perspectives of medical students I would not otherwise be able to get in my current job.” His wife, Kathleen Chien, BSN ’86, helps with the hosting duties when students visit them in Cleveland. Having hosted three students in the past two years, they first connected with then-student Vanessa Nienhouse to talk about Cleveland-area programs and met for dinner when she visited for her residency interview. This past year, the couple hosted two students, Rachel Payne and Ashley Patel, which eased the burden of their costly interview processes. The Chiens try to offer a homestay that fits the needs of the student guests, and they offer the flexibility and insight needed during the busy interview season. “My wife usually greets them, and they often head out to the pre-interview dinner, meet and greet,” Chien notes. “We get to speak with them when they get back and make sure that we have what they need for the next day. This year our student and another interviewee from another program went to dinner with us. We had a great conversation!” For more information about any of these programs, or to share Looking forward, Chien plans to continue to participate as an alumni an idea of how you would like to be involved with the COM, please contact host. He says, “It keeps me grounded and it’s an important way to give the Office of Medical Advancement at (312) 996-4470 or [email protected]. back to the institution.”

ILLINOIS MEDICINE | 33 class notes

News and Updates From University of Illinois College of Medicine Alumni

Donald Gore ’58, MD Presbyterian-St. Luke’s Medical Center David Mayer ’78, salt-based solution to help the patient ’60, MS, was named (now Rush University Medical Center) MD ’82, received the with weight and portion control. Board- a 2017 Top Doctor in and at the COM Chicago. Berent holds Humanitarian Award certified in gastroenterology, Gaston ’60 Wisconsin in recognition dual certification from the American ’82 from the Patient Safety is a Fellow of the American College of of his extensive expertise and clinical Boards of Psychiatry and Neurology, Movement Foundation, which identifies Gastroenterology and the American excellence. Retired since 2013, Gore and he provides a wide variety of the most influential advocates in College of Physicians. He is also a served as an orthopaedic surgeon, psychiatric treatments including patient safety and recognizes leaders member of the American Society for researcher and clinical professor at the family psychotherapy, dynamic who have made significant progress Gastrointestinal Endoscopy and the Medical College of Wisconsin. After psychotherapy, psychopharmacology, in eliminating preventable patient Association for Bariatric Endoscopy. medical school, holographic memory resolution and deaths. Mayer is vice president of Gaston completed his residency at St. he completed heart-centered hypnotherapy. A Life quality and safety for MedStar Health, Joseph Hospital in Chicago and his an internship at Fellow of the American Psychiatric the largest health fellowship in gastroenterology at Cook Milwaukee County Association, an award given for his care provider in County Hospital. General Hospital humanitarian service, Berent has a the mid-Atlantic and served as national reputation as a specialist in the region. In his Adrienne Fregia, a captain in the treatment of attention deficit disorder position, he MD ’88, was elected United States Air (ADD) and pediatric bipolar disorder. oversees the trustee of the Illinois Donald Gore Force, gaining infrastructure for ’88 State Medical Society extensive training in general surgery clinical quality and (ISMS) and re-elected as chair of the Daniel Hoffman ’74, David Mayer and all aspects of orthopaedic MD ’78, Res ’81, is its operational board of trustees during its 2017 annual surgery. He then completed a six- a physician at SSM efficiency, and he designs and directs meeting. A board-certified internist month biomechanics fellowship ’78 Health Medical Group system-wide activity for patient safety specializing in gastroenterology, she is at the University of California, San in Mount Vernon, Illinois. Board- and risk-reduction programs. Under in solo medical practice in Flossmoor, Francisco. In addition to teaching certified in internal Mayer, MedStar has been at the Illinois. An ISMS member since 1993, orthopaedic residents and medical medicine and vanguard of embracing transparency Fregia held the position of secretary- students, Gore also was involved geriatrics, Hoffman in communications with patients and treasurer and simultaneously served in clinical and basic research at the is interested in families when something goes wrong on the Finance and Medical College of Wisconsin and the chronic disease in treatment. MedStar worked with the Medical Benevolence former Wood Veterans Administration management, U.S. Agency for Healthcare Research Committee. In Medical Center, now known as the health-risk and Quality (AHRQ) to develop and addition, she served Clement J. Zablocki VA Medical Center, assessments, pilot a toolkit for their Communication on the Council on Daniel Hoffman located in Milwaukee. Board-certified and preventive and Optimal Resolution (CANDOR) Education and Health in orthopaedic surgery, Gore has medicine. After receiving his medical program. Workforce. She also received numerous awards, including a degree from the COM Peoria, he holds membership Adrienne Fregia Distinguished Service Award from the completed an internship and residency Darrien Gaston, MD in the American department of orthopaedic surgery, and at the University of Illinois at St. Francis ’84, was designated as Medical Association, the American two Teacher of the Year Awards from Medical Center in Peoria. a 2017 Premium Care College of Physicians, the American orthopaedic residents at the Medical ’84 Physician by United Gastroenterological Association, and the College of Wisconsin. Gore and his Gregory Gabliani, MD Healthcare, the highest of its four American Society for Gastrointestinal wife, Jacqueline, have established ’79, is a cardiologist designations. The Endoscopy. Fregia has been a member the Robert Jason Gore Scholarship, at SSM Health Medical United Healthcare of the Chicago Medical Society since a fund with the Wisconsin Medical ’79 Group in Troy, Missouri. Premium Program 1993. A California native, Fregia Society Foundation, in memory of their Gabliani completed his residency at assesses more completed her residency and fellowship grandson, Robert. Duke University Medical Center, then than 350,000 at Rush-Presbyterian-St. Luke’s Medical served a clinical physicians Center (now Rush University Medical Philip Berent, MD cardiology fellowship across the U.S. A Center) in Chicago. ’66, Res ’73, was at Parkland Hospital gastroenterologist Darrien Gaston recognized as a 2017 in Dallas and for the past 25 Aimen Shaaban, MD ’66 Top Doctor in Park an angioplasty years, Gaston opened Metropolitan ’91, has joined Ann & Ridge, Illinois, an award that honors fellowship at Gastroenterology Consultants in the Robert H. Lurie Children’s health care practitioners who have Harvard’s Beth Israel Beverly area of Chicago 18 years ’91 Hospital of Chicago as demonstrated clinical excellence while Hospital in Boston. Gregory Gabliani ago. The facility is accredited by the director of The Chicago Institute for delivering the highest standards of Board-certified Joint Commission with the Gold Seal Fetal Health and as patient care. An expert pediatric and in cardiology and internal medicine, of Approval. Gaston provides the professor of surgery adolescent psychiatrist, Berent has Gabliani taught at St. Louis University SlimSmart Balloon, a non-surgical, at Northwestern received several Top Doctor Awards for two years and practiced in St. Louis temporary weight loss procedure, as University Feinberg in his 40-year career. After receiving and Alton, Illinois. He later moved his well as the ORBERA© Managed Weight School of Medicine. his MD, he completed an internship practice to Troy, where he can focus Loss System, an FDA-approved Since 2012, at Illinois Masonic Hospital (now on what he truly enjoys: developing procedure in which a balloon is Shaaban had been Advocate Illinois Masonic Medical long-term relationships with patients to placed in a patient’s stomach using a fetal surgeon and Center), and residencies at Rush- improve their cardiac health. endoscopy and then filled with a safe, the director of the Aimen Shaaban

34 | SPRING 2018 COMMITTED TO SAFETY NET CARE research contributions relate to the Alumnus helped transform medical diagnosis and treatment of congenital services in Chicago community, diseases such as spina bifida, congenital diaphragmatic hernia, now works citywide sacrococcygeal teratoma, congenital pulmonary airway malformation, RT JONES, MD ’79, has transformed the health gastroschisis, omphalocele, twin- infrastructure of Chicago, first at the neighborhood twin transfusion syndrome, and fetal level and more recently citywide. bladder outlet obstruction. He receives Jones teamed with a pastor, Wayne Gordon, support for his basic science research whom he met his third year of medical school, program from the National Institutes to bring quality care to a hardscrabble Chicago of Health. Shaaban completed his general surgery residency at the neighborhoodA that badly needed it. Jose Zamudio They founded Lawndale Christian University of Iowa Hospitals and Health Center in 1984, and Jones Clinics, and his pediatric surgical Cancer Society, the Border AIDS helped build it from a shoestring clinic residency and post-doctoral fellowship Foundation, and Polo with a Mission. into a safety net for North Lawndale, in fetal surgery research at Children’s Zamudio completed his residency in the community where he lived for 35 Hospital of Philadelphia. obstetrics and gynecology at Texas years. Tech School of Medicine in El Paso. The health center, which Michael Wack launched thanks to countless volunteer ’87, MD ’91, Res Richard Makowiec, hours in a former Cadillac dealership ’96, practices MD ’94, has joined building, has grown to serve 164,800 with Seacoast Franciscan Physician visits annually, providing a wide range Orthopedics & ’94 Network Orthopedic Art Jones of services, various satellite clinics, a Sports Medicine Specialists in Indianapolis. He fitness center, a café and dental offices. in Newburyport, previously was associated with Jones, now a principal at Health Management Associates Massachusetts. Michael Wack Northwestern Medicine Surgery consulting, has continued his focus on improving Medicaid- In addition Center in Warrenville, Illinois. Board- based services by helping found a collective of 23 hospitals and to general orthopaedic surgery, certified in orthopaedic surgery with an more than 300 primary-care providers, called the Medical Home Wack has a special focus on knee, additional certified qualification in hand Network, who work together to improve basic care in Chicago. shoulder and foot conditions, as surgery, Makowiec Partners in the nonprofit network share information well as sports-related injuries. is a Diplomate through an Internet portal, giving medical staff a more complete Board-certified in orthopaedic with the National picture of patients’ health history with alerts, historical data surgery, he is a member of the Board of Medical and behavioral and social determinants of their health. Care American Academy of Orthopaedic Examiners and the coordinators contact patients who receive emergency room Surgeons, the Massachusetts American Board treatment to connect them with primary care physicians and any Orthopaedic Association and the of Orthopaedic needed specialists for follow-up visits and routine care. Massachusetts Medical Association. Surgery. A Fellow Richard Makowiec “Having access to real-time information and up-to-the- He has been practicing in the state of with the American minute details pertaining to each patient’s health care utilization Massachusetts since completing his Academy of is invaluable,” says Jones, who serves as the collective’s chief residency in 1996. Orthopaedic Surgeons, he has held medical officer. various academic appointments with Participants have experienced financial savings, declines Jose Zamudio, MD Northwestern University Feinberg in hospital readmissions, and increases in timely follow-up ’92, has been named School of Medicine and Chicago appointments with primary care doctors. And Jones has shared as a top 10 doctor in El Medical School. In 1999, Makowiec his expertise by speaking across the country about how to ’92 Paso, Texas, by Rate was a member of the medical staff redesign care in low-income and underinsured communities. MDS.com. Board-certified in obstetrics for the Chicago Cubs. He completed and gynecology, Zamudio has his internship in general surgery and — Rose Shilling consistently been voted America’s Top an orthopaedic surgical residency at OB/GYN by the Consumers’ Research Northwestern and a fellowship in hand Council of America. Castle Connolly surgery at the Indiana Hand Center Medical Ltd. has also named him a (now the Indiana Hand to Shoulder Center for Fetal Cellular and Molecular at the University of Iowa Carver Top Doctor. Zamudio is a Fellow of the Center) in Indianapolis. Makowiec also Therapy at Cincinnati Children’s College of Medicine, and as assistant American College of Obstetricians and served in the U.S. Navy Medical Corps Hospital Medical Center, as well as professor of surgery at the University Gynecologists and a member of the from 1992 to 2004. professor of surgery at the University of Wisconsin Medical School (now the American College of Obstetrics and of Cincinnati College of Medicine. Prior School of Medicine and Public Health). Gynecology, and the Robotic Surgery Raj Chandwaney to his work in Cincinnati, he served Shaaban has lectured nationally Council at Las Palmas Hospital in El ’90, MS ’92, MD ’96, as an associate professor of surgery and internationally and is among the Paso. He is passionate about outdoor was named chief of with tenure and as director of the most well-respected fetal intervention activities and uses his favorite sport, ’96 cardiology and director of Laboratory for Fetal Cellular Therapy surgeons in the world. His clinical polo, to raise funds for the American the chest pain center and cardiology

ILLINOIS MEDICINE | 35 telemetry unit at the role of natural killer cells in combating in orthopaedic surgery, Carreira has Oklahoma Heart recurrent viral infections. He also been practicing with a focus in the Institute in Tulsa. serves as co-director of the university’s areas of hip preservation and foot He has practiced Oliver Langenberg Pediatric Physician- and ankle surgery for more than 10 as an interventional Scientist Training Program and as years. He has served as a surgical cardiologist and director of the pediatric rheumatology instructor in both served as the fellowship program. An elected hip and foot/ STEMI program Raj Chandwaney member of the American Society for ankle arthroscopy medical director Clinical Investigation and the Society of on more than 30 at the Oklahoma Heart Institute Pediatric Research, French completed occasions for Ari Levy for more than 14 years. During his his pediatric residency at the Mayo ... organizations tenure, he helped the program Clinic School of Graduate Medical .J including the Levy started a workplace wellness transition from a 12-physician Education. He finished his fellowship Arthroscopy Dominic Carreira consulting firm and was previously one cardiology group to a state-of-the-art in pediatric rheumatology in 2003 at Association of of the Blackhawks’ team internists. cardiovascular tertiary referral center Washington University before joining North America and the International of excellence that now employs more the faculty. Society of Hip Arthroscopy. Carreira Jonathan Shepherd, MD ’05, Res than 45 cardiovascular specialists. has provided medical coverage for ’09, was named a 2017 Top Doctor Chandwaney is board-certified in Traci Powell ’94, many college and pro sports teams, in Woodlawn, Maryland, an award internal medicine, cardiovascular MD ’99, Res ’03, including the Miami Dolphins, Miami that honors clinical excellence and the disease, interventional cardiology and has earned Certified Marlins, Denver Broncos, U.S. Men’s highest standards of patient care. A endovascular medicine. He previously ’99 Physician Executive and Women’s Ski Teams, and the child, adolescent and adult psychiatrist, served as president of the American certification, a designation that Chicago Sky WNBA team. He also Shepherd is the chief medical director Heart Association’s Tulsa chapter, indicates a physician has achieved has served as a consultant for Cirque within Hope Health Systems Inc. He and more recently he was a member superior levels du Soleil and the Fort Lauderdale also has earned the titles of Diplomate of the American Heart Association’s of professional Strikers. He was an orthopaedic in Child and Adolescent Psychiatry Southwest Affiliate Regional Board excellence and surgery resident at Rush University and Diplomate in Psychiatry by the of Directors. After receiving his MD, management Medical Center in Chicago, and he American Board of Psychiatry and Chandwaney completed his internship education while completed three fellowships including Neurology. In addition to his clinical and residency at Baylor College of also demonstrating one in sports medicine and hip work, Shepherd is active within his Medicine in Houston, and fellowships effective healthcare arthroscopy at Steadman-Hawkins church and has participated in volunteer in clinical cardiology and interventional industry knowledge (now The Steadman Clinic) in Vail, Traci Powell mission trips. After completing his MD cardiology at Northwestern University and leadership Colorado. and residency, Shepherd completed Feinberg School of Medicine. skills. The designation is awarded by an additional residency in child and The American Association for Physician Liawaty Ho, MD, Res adolescent psychiatry at Johns Hopkins Anthony French MS Leadership®, the nation’s largest and ’02, has joined Nevada University School of Medicine. ’93, PhD ’95, MD ’97, only organization solely focused on Cancer Specialists, was named director leadership education and management ’02 specializing in oncology. Nathan Stitziel, ’97 of the division of training of physicians. Powell is the Ho completed her medical training at MD ’06, PhD ’06, pediatric rheumatology at Washington behavioral health medical director of the University of Indonesia Faculty of published research in the University School of Medicine in St. Harmony Health Plan in Chicago. Medicine in Depok City, Indonesia, ’06 Journal of the American Louis. An associate professor of and her residency at the COM College of Cardiology indicating that pediatrics, pathology, immunology, Dominic Carreira, Peoria. She also held a fellowship at individuals with two rare mutations of and biomedical engineering, French is MD ’00, has joined Montefiore Einstein Center for Cancer the ANGPTL3 genes have levels of noted for his research, funded by the Peachtree Orthopedics in Care in the Bronx, New York. triglycerides that are far below normal, National Institutes of Health, on the ’00 Atlanta. Board-certified protecting them from coronary disease Ari Levy, MD ’05, MBA, was listed in Crain’s Chicago ’05 Business’ “40 under 40.” He is the founder and CEO of SHIFT, a concierge medical practice in Chicago that provides a fully integrated approach to health care by bringing together board-certified doctors, dedicated coaches, fitness trainers, nutritionists and recovery specialists under one roof. Since the startup launched in March 2017, it has grown to more than 315 members. Levy, who worked as a personal trainer to help pay for college and medical school tuition, also serves members as one of their primary care Anthony French physicians. Before launching SHIFT, Nathan Stitziel

36 | SPRING 2018 HONING THE CRAFT OF MEDICAL IMAGING even if they have other risk factors. Radiologist a prominent contributor as an associate professor at the He went on to lead an international of ideas to improve the field University of California, Irvine in the group of researchers who looked for division of hematology oncology, mutations that destroyed the gene, where she received the prestigious finding that it occurred in just one 1 in AMES BORGSTEDE ’70, MD ’74, has taken a C. Ronald Koons, MD Humanitarian 309 people. But he and his colleagues leadership role in helping radiologists do their jobs well. Award for service and compassion to discovered the mutation reduced heart Alongside his clinical practice and professorship patients. attack risk by a third. As a result of at the University of Colorado in Denver, Borgstede Stitziel’s research, along with that of has committed himself for years to the mission of James Cheon, MD others, two pharmaceutical companies the Radiological Society of North America. Now, he’s ’11, has joined Allied are now testing drugs based on the Jboard chair of the organization, which Anesthesia, a Southern genetic mutations in hopes of finding provides a forum for conversations about ’11 California medical group the next blockbuster heart disease incorporating advances and providing that provides adult and pediatric treatment. Stitziel is the director of the the best possible care. services to several area hospitals. Center for Cardiovascular Genetics, An RSNA member since 1976, Board-certified in anesthesiology, the director of the McDonnell Genome Borgstede lectures, gives scientific Cheon practices at Institute, and assistant professor presentations and publishes articles Children’s Hospital of medicine and genetics at the about issues such as safety standards of Orange County, Washington University School of and the dramatic increase in diagnostic St. Joseph Hospital, Medicine in St. Louis. After receiving imaging—and when it’s truly warranted. and the Orthopaedic his MD and PhD in bioinformatics He has presented at more than 100 James Borgstede Institute for Children from the COM, Stitziel completed scientific and educational meetings in Los Angeles. After his residency at the University of around the world. receiving his MD, James Cheon Chicago, a cardiology fellowship at International service has long been part of his career, Cheon completed the Brigham and Women’s Hospital with projects in the Philippines, Cameroon and Haiti, where he his residency at the University and Harvard Medical School, and traveled multiple times with the American College of Radiology of Chicago. He was a pediatric a combined postdoctoral research to provide radiology services and education at Grace Children’s anesthesia fellow at Children’s Hospital fellowship in cardiovascular genetics Hospital in Port-au-Prince. Los Angeles. at Massachusetts General Hospital, A reviewer for the Journal of the American College Broad Institute, and Brigham and of Radiology and past president of the group’s Board of Krista Childress, MD ’11, has Women’s Hospital. He joined the Chancellors, Borgstede received the organization’s highest joined Children’s Healthcare of Atlanta faculty at Washington University in honor in 2009, the peer-nominated Gold Medal for distinguished and Emory University School of fall 2012. and extraordinary service to the discipline. It’s one of many Medicine as an assistant professor awards he has received through years of affiliations with of obstetrics and gynecology. Nitin Kumar, MD numerous professional groups, including the International Board-certified in obstetrics and ’07, has joined the Society of Radiology, where he formerly served as president. gynecology, Childress is a member HSHS Medical Group Borgstede also has been an active presenter at the RSNA’s of a number of professional societies ’07 in Effingham, Illinois. A yearly assembly. “The RSNA annual meeting is the venue for including Alpha Omega Alpha, the gastroenterologist, Kumar is skilled in education and research presentations and for radiologists American Society for Reproductive colonoscopies, endoscopy, intragastric around the world to meet face to face and discuss issues Medicine, the American Congress of balloon placement, and specialization relevant to the future of our specialty for the benefit of our Obstetricians and Gynecologists, the in obesity medicine. patients,” he says. American Association of Gynecologic After earning his — Rose Shilling Laparoscopists, the North American MD, he completed Society for gastroenterology Pediatrics and and advanced Adolescent endoscopy Gynecology, and fellowships at Group and Verity Health System primary investigator for 20 oncology the Pediatric Harvard Medical in southern California. A nationally trials, Seery has research experience Initiative Network- School’s Brigham Nitin Kumar renowned medical oncologist who in neoadjuvant chemotherapy, The Oncofertility and Women’s specializes in treating cancers of intraoperative chemotherapy for Consortium. Hospital. Board-certified in internal the pancreas, pancreatic cancer, and treatments She received Krista Childress medicine, gastroenterology and obesity esophagus, for neuropathic pain. A dedicated an Outstanding medicine, Kumar is a member of the colon, rectum, teacher, Seery was featured at the Teacher Award from Northwestern American Society for Gastrointestinal anus and Hematology/Oncology Fellowship University Feinberg School of Endoscopy, the American Pancreatic liver, Seery Annual Lecture Series. After receiving Medicine, and her Mental Health Association and the Association for has extensive her medical degree from University PG Prize Paper was selected by the Bariatric Endoscopy. experience in College Dublin School of Medicine, Scientific Program Committee of the researching she did her residency and fellowship American Society of Reproductive Tara Seery Tara Seery MD, Fel pancreatic training in hematology/oncology Medicine in 2014. After receiving ’08, has been appointed cancer, with multiple scientific at Caritas St. Elizabeth Medical her MD, Childress completed her director of the newly publications. She is one of the Center in Boston and completed residency at Northwestern University ’08 established pancreatic nation’s highest enrollers in early her fellowship training at the COM Feinberg School of Medicine and a cancer program at Verity Medical phase pancreatic cancer trials. The Chicago. Most recently, she served fellowship in pediatric and adolescent

ILLINOIS MEDICINE | 37 LOYOLA GETS NEW LEADERSHIP College of Medicine alumnus promoted to president

HAD WHELAN, MD ’93 has been promoted from senior vice president Columbia University and the staff of and chief medical officer to president of Loyola University Medical Center New York-Presbyterian, respectively, in Maywood, Illinois. The new role will expand Whelan’s influence on as an assistant professor of clinical improving quality of care at the Chicago-area hospital. dermatology and the director of After receiving his MD at the COM, Whelan completed his residency Milstein and Allen Hospitals inpatient at the University of Minnesota and launched his career at the University consultation. Gallitano is active with Cof Michigan before spending almost a decade as a physician with University of the Women’s Dermatologic Society, the Chicago Medicine. Whelan joined Loyola as director of its division of hospital Society of Dermatology Hospitalists medicine in 2009, and he returned to the University of Chicago in 2011 as chief and the American Academy of associate medical officer for performance improvement and innovation. Chad Whelan Dermatology. After receiving her MD, Whelan rejoined Loyola University Medical Center in 2015 to serve as senior she completed her medical internship vice president and chief medical officer. “Dr. Whelan has exhibited tremendous skill in leading our quality at New York University Hospital and initiatives as chief medical officer,” says Larry Goldberg, president and CEO of Loyola parent company her dermatology residency at SUNY Trinity Health Illinois. “He is a talented and experienced healthcare leader who will guide Loyola into the Downstate Medical Center, where she future with a focus on providing highly coordinated and high-value care across the continuum.” served as chief resident. Whelan is board-certified by the American Board of Internal Medicine and is also a professor in the department of medicine at Loyola University Chicago Stritch School of Medicine. Michael Plachta ’09, MD ’13 has — Ian Murphy joined the Colorado Springs Health Partners (CSHP) after completing his residency in family medicine at the University of South gynecology at Baylor College during her highly successful career Georgina Aldridge, Carolina School of of Medicine Education at Texas at the MD Anderson Cancer Center. PhD ’11, MD ’13, Medicine, Palmetto Children’s Hospital. During her tenure, she founded the is on staff at the Health Richland in PA Oncology Fellowship Program ’13 University of Iowa Columbia, South Maura Polansky, PA-C, MS, MHPE and directed PA education for more Hospitals and Clinics. She earned Carolina. CSHP is Michael Plachta ’11, has been named chair and than a decade. She has also been her medical degree part of the DaVita associate professor in the department engaged in medical education and and her PhD at the Medical Group based in Colorado of physician assistant (PA) studies at research, with extensive publications University of Illinois Springs. Plachta is a member of the El the George Washington University focused on PA training and practice. and completed Paso County Medical Society. School of Medicine and Health Polansky is a PhD candidate in a residency in Sciences. She previously served the School of Health Professions neurology at the Matthew McKnight, as program director for curriculum Education at Maastricht University University of Iowa DDS ’11, MD ’14, is on staff at Advocate Christ development in the department of in the Netherlands. She received her Hospitals and Clinics Georgina Aldridge clinical education at the University of Master of Health Profession Education in Iowa City. ’14 Medical Center in Oak Texas MD Anderson Cancer Center (MHPE) from the COM Chicago, and Lawn, Illinois. McKnight earned both in Houston. Over the past 22 years, her master of science degree and PA Stephanie Gallitano, MD ’13, his doctorate in dental surgery and Polansky has served in several clinical training from the Baylor College of has joined the faculty of the College his MD from the University of Illinois. and administrative leadership roles Medicine. of Physicians and Surgeons at He also has completed advanced

NEW LEADERSHIP FOR ISMS College of Medicine alumna assumes one-year term as president in April

ATHERINE TYNUS, MD ’93, has been elected to a one-year term as president-elect of the Illinois State Medical Society (ISMS). Tynus has been active with ISMS since 2006, and she currently serves on its Executive Committee and Committee on Finance and Medical Benevolence; previously, she served on the society’s Medical Legal Council and its Council on Membership and Advocacy. A Chicago native, Tynus attended Resurrection College Prep High School, Northwestern University and the College of Medicine Rockford before completing a residency in internal medicine at Loyola University Medical KCenter in Maywood, Illinois. She then moved to MacNeal Hospital in Berwyn, Illinois, to serve as chief resident in internal medicine, eventually becoming program director of the hospital’s Transitional Year Residency Program. During her tenure at MacNeal, the American Medical Association honored Tynus with an AMA Physician’s Recognition Award. Board-certified in internal medicine, Tynus now practices at Northwestern Medicine in Chicago and is a clinical Katherine Tynus associate professor at Northwestern University Feinberg School of Medicine. A fellow of the American College of Physicians and a member of the Association for Hospital Medical Education, Tynus serves on the executive committee of the Council of Transitional Year Program Directors, and she has lectured extensively on residency training issues such as career planning, patient safety and quality improvement. Tynus is also active in the Chicago Medical Society, where she served as president in 2015–2016. In addition to educating future medical professionals, Tynus continually strives to teach the public about diabetes, heart disease, osteoarthritis and other topics by participating in community health fairs and events. — Ian Murphy

38 | SPRING 2018 training in oral and maxillofacial surgery at the University of Illinois, as well as training at Northwestern, Christ Advocate, Jesse Matthew McKnight Brown VA, and the University of Illinois Hospital & Health Sciences System. McKnight uses the newest techniques and state-of-the-art virtual planning for all types of surgical cases including 2019 Illinois Medicine dental implants, orthognathic, trauma and benign pathology. McKnight is a member of the American Dental Association, the Illinois State Dental Award Nominations Society, the Chicago Dental Society, the American Medical Association and the American College of Surgeons. Now OPEN! He is board-eligible for the American Board of Oral and Maxillofacial Surgery and American College of Surgeons. Our Illinois Medicine Awards celebrate leaders, alumni and friends who have made important contributions to the College Vivek Upadhyay, MD ’15, married of Medicine and have advanced the field of academic medicine, Salina S. Bakshi, MD, medical research or clinical practice; or who through their character ’15 on Aug. 26, 2017, in Rockleigh, New Jersey. Upadhyay is and accomplishments have given extraordinary service to patients, a resident physician students and communities, especially the underserved. in internal medicine at Massachusetts General Hospital Nominate a classmate, colleague or peer in one of the five categories: in Boston and is pursuing a fellowship in hematology/ PIONEER IN MEDICINE oncology. He Vivek Upadhyay received an MD with INNOVATOR OF TODAY honors from the COM. The bride is a resident physician in internal medicine EMERGING INNOVATOR at Brigham and Women’s Hospital in Boston. She received a medical degree DISTINGUISHED ALUMNUS from the Icahn School of Medicine at Mount Sinai in New York. SPIRIT OF MEDICINE

For more information on each of the award categories or to make a nomination go online here: go.uic.edu/COMawards or contact the office of Alumni Engagement at [email protected] or (312) 996-4470.

TELL US what you’re up to! Your classmates are curious about what you are doing. Send your latest news and accomplishments via e-mail to [email protected], and we’ll be sure to include them in the next issue of Illinois Medicine.

ILLINOIS MEDICINE 39 REUNION 2018 Join us October 11-13 to Celebrate Illinois Medicine THURSDAY, OCTOBER 11 • Golden Alumni Dinner Honoring the 50th Reunion Class of 1968

FRIDAY, OCTOBER 12 • College of Medicine Tours and Open House • All Reunion Class Reception – Honoring Golden Alumni Society Members and All Reunion Classes from Graduating Years Ending In 3 and 8

SATURDAY, OCTOBER 13 • Explore UIC & Chicago - An open day for alumni to gather with their classes, explore the city’s attractions or participate in UIC programming (more information to come). Get Involved If you are interested in becoming a class volunteer or have additional questions, please contact the Office of Alumni Engagement, at (312) 996-6815 or [email protected].

A block of hotel rooms will be reserved for Oct. 11-13. Booking and discount information will be posted in the reunion section of our website when it becomes available.

For the latest up-to-date information visit: http://go.uic. edu/ILMedReunion2018

40 | SPRING 2018 in memoriam INTERNIST, HEALTHCARE LEADER HAD JUST CELEBRATED INVESTITURE

Michael Anthony Werckle, MD ’66, died on March 28, 2018, after returning home from an investiture ceremony in his honor FACULTY at the College of Medicine Rockford, which had created the

Michael A. Werckle, MD, Endowed Professorship in Biomedical John Erickson, MD ’51, Res ’57, Sciences. died on Sept. 27, 2017, in Sterling, The day of celebration was a highlight of his lifework and serves as an ongoing tribute to Illinois. A mentor to senior medical Werckle’s legacy as a compassionate physician, respected educator and dedicated public servant. students and an instructor at the Born in Peoria on August 10, 1939, and raised in Rockford, Werckle planned to be a doctor College of Medicine from 1957 until from an early age. He worked to pay his way through Cornell College in Mount Vernon, Iowa, where 1970, Erickson was in private practice he graduated in 1962, and COM in Chicago. He completed his internship and residency through the at the Sterling Rock Falls Clinic for University of Michigan at Wayne County General Hospital, where he quickly rose to become director 36 years until his retirement in 1993. of the outpatient department and long-term care facility. During the Korean War, he served in In 1973, Werckle returned to Illinois to serve as associate director of the Illinois Department of the Navy as a physician with the 1st Public Health, where he was instrumental in the effort to vaccinate school children during the 1976 Marine Division. A Diplomate of the outbreak of swine flu. In 1977, he moved back to his hometown of Rockford, where he joined the American Board of Internal Medicine faculty of the then-newly formed COM campus there as assistant clinical professor of medicine, a and a Fellow of the American College position he held until his passing. of Physicians, Erickson mentored In 1980, Werckle opened North Alpine Medical Clinic (later Rockford Clinic on North Alpine) in medical students who joined him an area that had been underserved. He practiced internal medicine there, specializing in geriatrics, for 12-week sessions in which they until his retirement in 2006. Werckle loved his work there, often commenting that it didn't feel like participated in office appointments, work because he spent all day visiting with his friends. house calls, and daily hospital The investiture was the last of many awards and honors Werckle received during his life, inpatient care at CGH Medical Center including two Golden Apple Awards, a Faculty Distinguished Service Award, and the Arnold P. Gold in Sterling. He served nine years on Foundation Humanism in Medicine Award. The Endowed Professorship in Biomedical Sciences in the Sterling Elementary Board of his name was made possible by a grant from the Blazer Foundation. Education and terms on the alumni He was also a physician leader: Werckle served on the boards of Rockford Health System, boards of both Augustana College Lifescape Community Services, Wesley Willows, Visiting Nurses Association, and many others. He and the University of Illinois. Erickson served as president of medical staff at Rockford Memorial Hospital and was medical director of and his wife, Marian, were married many organizations, including Rockford Clinic, Fairhaven Christian Retirement Center, Willows on for 66 years. Together, they enjoyed Main, Alpine Fireside Health Center, and In Home Medical Group. In 2017, Werckle became majority prized nightly family dinners, school owner of Hospice Care of America, where he had served as medical director since 2006. and church activities, vacations Werckle will be remembered for his warmth of spirit and caring nature. He believed in the in Wisconsin and extensive travel healing power of simply listening compassionately to people. Recalling his working-class roots, he throughout the U.S. Among his never refused care to anyone for the inability to pay. hobbies, Erickson enjoyed tennis, Werckle is survived by his wife Patricia Ann (Petzinger) Werckle of Rockford; children Michael golf, reading and singing in his church David Werckle of Rockford, Elizabeth Ann Werckle of Machesney Park, Illinois, and Sarah Kathryn choir. The couple had three children, (Matthew) Rip of Coal Creek Canyon, Colorado; grandchildren Anne Lee Harris, Dashiell Michael eight grandchildren and five great- Rip and Lincoln Russell Rip; sister Jacqueline (Werckle) White; and brothers W. David Werckle grandchildren. (Sara), and Richard L. (Linda) Werckle. He was predeceased by his parents and a sister, Patricia Werckle Zeller. Lawrence Frohman, MD, died in March, 2018. Professor emeritus and Michael Anthony Werckle and his family enjoy the investiture ceremony in his honor at the College of Medicine former Edmund F. Foley Chairman Rockford that officially created the Michael A. Werckle, M.D. Endowed Professorship in Biomedical Sciences. of Medicine at the COM from 1992 to 2001, Frohman had recently received the Outstanding Leadership in Endocrinology Award from the Endocrine Society for his long and distinguished career as a scientific and clinical leader, accomplished basic and clinical mentor, as well as for his outstanding teaching, service and administrative achievements. He successfully led research, education and clinical programs, and he directed fellowship training programs for MDs and PhDs, many of whom are now in leadership positions throughout the world. In the wider field of endocrinology, Frohman served as

ILLINOIS MEDICINE | 41 LEADER IN ANESTHESIOLOGY Korean War, eventually retiring as a lieutenant colonel. After the Korean War, The once longtime head of Haley established a private practice in Lakewood, Washington, but also treated anesthesiology at the College of Medicine patients in Bolivia, Rwanda and Pakistan. Chicago, Ronald F. Albrecht ’59, Pursuing a career in politics, he was elected to represent the 28th district in MD ’61, Res ’66, led a distinguished Washington’s House of Representatives career in the field of anesthesiology. in 1974 and re-elected for two additional terms. He was subsequently elected to He touched the lives of countless the Washington State Senate in 1979 to students, residents and colleagues fill a partial term and then elected to a four-year term in 1981. Former President across five decades and leaves a legacy Gerald Ford campaigned for Haley of professionalism and service after his during his run to unseat U.S. Rep. Norm Ronald F. Albrecht Dicks in 1996, but he lost that election. passing in September 2017. Haley advocated for the legalization The Chicago native earned his undergraduate degree in psychology and composition from the of medical marijuana and was one of University of Illinois in 1959 before pursuing his medical degree from the College of Medicine Chicago. the prominent endorsers of the 1997 After an internship at Cincinnati General Hospital, Albrecht returned to Chicago for a residency in measure that did so in Washington state. anesthesiology at the University of Illinois Research and Education Hospital. In 2003, Haley became an associate professor of surgery at the COM. A lover Though Albrecht would subsequently leave Chicago for a stint at the National Institutes of Health of mountaineering and skiing, Haley in Bethesda, Maryland, his hometown soon lured him back. He accepted an academic appointment passed along his passion for outdoor at the COM and began practicing and teaching at Illinois Masonic Hospital before becoming head of sports to his children and grandchildren. anesthesiology at Michael Reese Hospital in 1971. His grandson, Colin Haley, is a With the 1989 merger of Michael Reese and the UI Hospital (which would later become the professional mountaineer. Haley’s first University of Illinois Hospital & Health Sciences System, or UI Health), Albrecht was named chair of wife, Margaret Shaw Haley, died in 1972. the department of anesthesiology, where he helped to define both the medical school curriculum and He is survived by his second wife, Rosel the anesthesia residency educational program. Upon his retirement in 2007, he was named professor Haley. emeritus of anesthesiology. Over the decades, Albrecht trained more than 500 anesthesiology residents and published more Thomas Henderson, MD, PhD, died than 200 articles in peer-reviewed journals, including research related to the actions of anesthetics in 2017. A scholar, dedicated teacher on the cardiovascular system and the effects of anesthesia drugs on brain ischemia. He also served and administrator, Henderson joined in leadership positions with UI Health medical staff, the Illinois Society of Anesthesiologists, and the the College of Medicine in 1968 as a Association of Academic Anesthesiology Chairs. professor of biochemistry and molecular biology. A native of North Carolina, he — Daniel Smith remained in his home state until he received his doctorate in microbiology and nutritional biochemistry. Henderson undertook several demanding postdoctoral roles at the University of president of the Pituitary Society University of Michigan College of from Columbia University in New York Chicago before being recruited to the and the Central Society for Clinical Medicine, Frohman was married for and was the chairman of the division of COM. Throughout his long career, he Research, and he also served on more than 60 years to Barbara (nee urology at Cook County Hospital (now was accorded nearly every teaching the Endocrinology Study Section Hecht) and had four children and Stroger Hospital) from 1975 to 1985. award offered by the University of Illinois and chaired the Endocrinology eight grandchildren. Guinan also served as chairman of the colleges of Medicine and Dentistry in Program Advisory Group, the NIH’s Hektoen Institute of Medicine, which Chicago. Not only that, Henderson was National Hormone and Pituitary Patrick Guinan, MD, MPH, died partners with institutions, community also involved in the work of more than 70 Program. Frohman served on the on Sept. 8, 2017. A former chair organizations and investigators working committees or task forces that shaped VA Endocrinology Merit Review of urology and clinical associate to improve care and resources for the the institution’s direction and policies, all Board, the FDA Endocrine- professor of urology at the College underserved. while carrying a heavy teaching schedule Metabolism Review Committee, of Medicine Chicago, Guinan and conducting a productive NIH-funded and he chaired the USP Expert was the co-editor of “A History of Ted Haley, MD, died on Oct. 1, 2017. research program. Over the years, Advisory Endocrinology Committee. Surgery at Cook County Hospital.” A surgeon, politician and educator, Henderson also took an active role in The former head of endocrinology After completing his internship Haley was an associate professor of managing units that were undergoing and metabolism at SUNY Buffalo, and urology residency at Cook surgery at the College of Medicine. changes, ensuring smooth transitions in Frohman also served at Michael County, he became the director He received his medical degree from important administrative areas as both Reese Hospital in Chicago and the of urology for the City of Chicago the University of Rochester School acting dean of the Graduate College as University of Cincinnati College Department of Health. He earned of Medicine and served as a doctor well as acting associate vice chancellor of Medicine. A graduate of the a master’s degree in public health with an Army MASH unit during the for research.

42 | SPRING 2018 writing appeared in high-impact what is now Loyola University Chicago journals. He also enjoyed steady Stritch School of Medicine. After a research funding and trained many two-year internship at the former young investigators. In 2017 he was Cook County Hospital, Saletta served named a Fellow of the American two years as an Air Force captain at Society of Clinical Oncology for Whiteman Air his dedication and service to the Force Base in field of cancer. “In my 37 years in Missouri. He oncology and hematology, I’ve been came back to able to witness and participate in Cook County clinical trials that cure and ameliorate Hospital in many different kinds of tumors, 1965 for a four- and save may patients’ lives,” he year surgical said upon receiving the fellowship. residency, “To be recognized in this fashion followed by a by the American Society of Clinical fellowship in John Saletta Oncology, whose membership was surgery at the responsible for so many of these Lahey Clinic in Boston. Saletta then advances, is truly an honor.” returned to Cook County for a six-year Ted Haley campaigns for Congress with former President Gerald Ford stint as an attending surgeon and John Roger Powell ’58, MD also served as chief of the division of Frank Lesko, MD ’45, died on Howard Ozer, MD, PhD, died ’59, died on Oct. 4, 2017. A clinical general surgery and program director Aug. 15, 2017. A radiologist in the on April 6, 2018. Ozer served as associate professor at the COM, for surgical residents. Saletta later Champaign, Illinois, area, Lesko also chief of the division of hematology/ Powell will be remembered for his became an attending surgeon at Holy held a number of appointments, oncology at the COM Chicago from Illini spirit, Irish heritage and affinity Cross and left in 1982 for what is now including clinical associate professor 2010-12, director of the UIC Cancer for helping others both personally Advocate Lutheran General Hospital in at the College of Medicine, lecturer for Center from 2012-14, and as Eileen and professionally. After receiving his Park Ridge, Illinois, where he served as the University of Illinois speech and Lindsay MD, Powell completed his residency chairman of the division of surgery until hearing departments, consultant in Heidrick at Cook County Hospital. Certified 1989. On staff at Lutheran General radiology to the University of Illinois Professor of by the National Board of Medical for nearly 35 years, Saletta led the Veterinary School, and consultant to Oncology. Examiners and the American Board department of surgery and promoted the department of radiology at the Ozer’s of Obstetrics and Gynecology, he the hospital’s efforts to become a Level Veterans Affairs Illiana Health Care passion for delivered more than 10,000 babies I trauma center. Saletta and his wife of System in Danville, Illinois. After research throughout his career. From 1963 more than 50 years, Suzanne, had five receiving his MD from the COM, he and clinical to 2002, Powell practiced at Carle children and 11 grandchildren. did residency in radiology at Indiana studies also Foundation Hospital in Urbana, University Medical Center and led him to Illinois, and he served as courtesy Howard Ozer then served as a radiologist at St. become a staff at Mercy Hospital, McKinley Elizabeth Hospital in Danville. Lesko senior leader of the Gastrointestinal Health Center and Paris Community ALUMNI was president and medical director Cancer Working Group at UIC and Hospital. Powell also was the of Champaign Radiology Associate the director of the UI Health Tumor medical director and vice president Bernard Greenwald, Inc. and Midwest Nuclear Inc., which Registry. Prior to joining the COM, at Carle Clinic Association from MD ’43, died on Aug. provide radiology services to Urbana- Ozer served as division chief of 1980 to 1991. Powell was preceded 1, 2017. Among the area hospitals. Lesko, who served in medical oncology at the University in death by his first wife, JoAnn ’43 first to bring fathers the U.S. Army Medical Corps in World of North Carolina; chairman and Winterhalter, and he is survived into the delivery room, Greenwald was War II and the Korean War, received a director of the Winship Cancer by his second wife, Kathleen, instrumental in proactive health care letter of commendation for the role he Center, Emory University School of three children, four stepchildren, to aid in the early detection of cervical played in the evacuation of an airman Medicine, Atlanta; director of the five grandchildren, and five step- cancer and an who was seriously injured in a fall down cancer center of MCP Hahnemann grandchildren. early adopter the slope of Mount Fuji, Japan. The University, Philadelphia; and both of natural first Eagle Scout in Westville, Indiana, chief of the section of hematology/ John Saletta, MD, died on June childbirth he also received the “Wall of Fame” oncology, and director of the OU 19, 2017. A longtime professor at the techniques. award from Westville High School for Cancer Center at the University COM, Saletta helped establish the He delivered his lifetime achievements in 2013. of Oklahoma. He obtained his first Level 1 trauma center at Cook more than Lesko enjoyed golfing, tennis, fishing, MD and PhD degrees from Yale County Hospital and championed 10,000 babies, UI sports, gardening and reading. University and did his residency at the trauma center at Lutheran affectionately He is survived by his wife, Dorothy, Massachusetts General Hospital General. Born at Holy Cross Hospital known as Bernard Greenwald four children, two stepdaughters, five in Boston. In addition to playing a in Chicago, where his father was “Bernie grandchildren, four step-grandchildren, leadership role in multiple prestigious once chief of surgery, Saletta grew Babies,” during his 56-year medical two great-grandchildren and one step- institutions, Ozer undertook up in the Beverly neighborhood. He career. Greenwald served as the chief great-grandchild. innumerable clinical trials and his received his medical degree from of OB/GYN department at Lutheran

ILLINOIS MEDICINE | 43 LONGEST-SERVING DEAN IN ROCKFORD, CREATOR OF RMED

Bernard “Buz” Salafsky,

General Hospital in the 1960s and PhD, the longest serving started the OB/GYN department at dean of the College of Skokie Valley Hospital, now known as NorthShore University HealthSystem- Medicine Rockford, joined Skokie Hospital. A Naval Officer the campus in 1977 as a during World War II, Greenwald served in the Pacific Theater. He was biomedical sciences faculty an accomplished photographer, avid member and went on to world traveler, animal lover and lifelong learner. He was the beloved husband serve as the regional dean of Betty Koenig Greenwald and the late from 1983 to 2004. Edna Greenwald, the father of three, Among his contributions to the College of stepfather of one and grandfather of nine. Medicine was the creation of the Rural Medical Education Program (RMED), which he developed Bernard “Buz” Salafsky Glenn Chamberlin with an eye toward expanding access to health ’50, MD ’52, died care in underserved communities. Since 1993, on Dec. 10, 2017. more than 200 students have participated in the curriculum, and 70 percent of RMED’s graduates ’52 Chamberlin served the now practice primary care medicine in rural Illinois. The program underscores a legacy of patient- community of Monmouth, Illinois, for centric, primary care-focused education that Salafsky built at the College of Medicine. 35 years as a physician. A World War Born in 1935, Salafsky received his doctorate from the University of Washington and II veteran, Chamberlin was part of the worked internationally before landing in Rockford, where he made his mark on the community. In Army Specialized Training Program and addition to his leadership at the College of Medicine, Salafsky also researched tropical diseases. participated in the Battle of Okinawa Remembered as a leader, innovator and gifted communicator in his professional life, Salafsky lived in the Pacific Theater. He was one of modestly and loved books, The Economist magazine, plants and storytelling. the soldiers assembled on the island Salafsky is survived by his wife Marilyn; brother Ira; sons Joshua, Daniel and David (Yissel); of Ie Shima and grandchildren Ethan, Isaac, Madeline and Phoebe. A celebration of his life was held last awaiting September at the COM Rockford. His family suggested donations to the College of Medicine in lieu orders to of flowers. invade Japan when — Melissa Maleske President Truman ordered the atomic Burton Fink ’51, practice he started in the San States Navy bombing of MD ’53, died on Fernando Valley grew to five partners following the Glenn Chamberlin Hiroshima and Dec. 20, 2017. Likely and thrives today, continuing his Korean War Nagasaki. Chamberlin then served in ’53 the first pediatric traditions of patient-centered and as a ship’s Korea before being discharged from cardiologist in the San Fernando academic care. Fink’s membership doctor on the the service in 1946. After receiving his Valley, California, area, Fink was a in the SAGE (Study, Activity, Growth, USS General MD, he completed an internship at the World War II veteran and lifelong Enrichment) Society brought new H.B. Freeman, University of Indiana Medical Center in learner. He served for more than a interests and community. He traveled stationed Indianapolis and worked for a general half-century at Cedars-Sinai Medical the world and loved photography, in Oakland, medical practice in Seneca, Illinois, Center as opera, fine art, nature’s wonders and Leo Green California, for two years before establishing his head of the best of wines. He is survived and Seattle. He fulfilled his mission in practice in Monmouth. A secretary of pediatric by his cherished companion, June life of becoming a family practitioner, the Warren County Medical Society cardiology, Adler, two daughters and one launching his successful medical for 35 years, Chamberlin was also a vice chief grandson. He was preceded in practice in 1956. Then, for almost Diplomate of the American Board of and chief death by his youngest daughter; the 10 years after he had retired from Family Physicians and a board member of staff. mother of his daughters, Diana Goss practice in 1995, Green served in an of the Monmouth Community Memorial Many (nee Diane Gossman); and second administrative role as vice president Hospital. He also served two terms as consider wife, Flo Truitt Fink. of medical affairs at Alton Memorial his Hospital. He was a longtime member president of the Warren Achievement Burton Fink School Board, a school for people handbook Leo Green ’51, MD ’53, died of St. Ambrose Parish in Godfrey, with disabilities that he helped found. on diagnosing congenital heart March 2017. A family practitioner for Illinois. A lover of horses, Green was A loyal Cubs fan, he was an also an disease to be indispensable for 39 years, Green had a lasting impact a lifelong fan of thoroughbred racing avid reader who enjoyed taking a daily medical students and physicians. on many Alton, Illinois, area medical and frequented the Kentucky Derby one-hour walk and playing bridge. After medical school, Fink took an facilities. To put himself through and Keeneland race track in Lexington, Chamberlin and his wife, Patricia, were internship at Los Angeles County medical school, he worked as an Kentucky. He and his wife of 65 years, married for 67 years. They had three Hospital, then fellowships at both elevator operator. After receiving his Eulalia, had six children—including a children and five grandchildren. County and UCLA. The private degree, Green served in the United son, Chris, who followed in his father’s

44 | SPRING 2018 MEMORIAL A NEONATOLOGY GIFTS

PIONEER To make a memorial gift Alvin Miller ’51, MD ’53, spent to the college, please more than 60 years as a pediatrician contact the Office of in the Los Angeles area, setting a Gardener. Medical Advancement at high bar for energy and longevity He was also a history (312) 996-4470 while emerging a trusted expert in buff and neonatal care. loved music. or [email protected]. Funk was Miller began his career as married to a pediatric physician at Kaiser his late wife, Permanente Medical Center in Mildred, for Panorama City, California. Sparked Donald Funk more than 50 America. After his military service, by the premature birth and years. They had two sons and Hamilton returned to his practice in respiratory distress of his own son, many grandchildren and great- Urbana and served as team physician Miller became particularly attentive grandchildren. for Urbana High School football to the treatment of premature and University of Illinois football for babies and helped to establish Norman Halfpenny ’54, MD ’56, several years. He temporarily “retired” the neonatal intensive care unit at died on Nov. 4, 2017. Halfpenny was to Sarasota, Florida, in 1983, but Kaiser Panorama City. Other Los Alvin Miller a Salinas, California, physician for then established two urgent care Angeles area hospitals soon turned 48 years. After receiving his MD on centers. Deciding that retirement to him for help caring for their premature newborns and, later, the Peoria campus, he served as wasn’t for him, Hamilton returned as a resource to help establish their own NICUs. the flight surgeon on the USS Bon to Urbana and resumed his work in Eventually, Miller took his expertise abroad. He traveled Homme Richard (CV-31). While in the family practice, in the occupational to Romania in 1991 to teach perinatal and neonatal care Navy, Halfpenny visited Salinas, fell in medicine department at Christie to clinicians in a country seeking stability after the fall of love with the town and arrived there a Clinic. In 2010, he finally did retire to communism. That experience led Miller to develop Project short while later with his first wife and Birmingham, Alabama, where he was NEWSTART, which has provided comprehensive neonatal care five children in 1957. After completing active in the First Christian Church. instruction to healthcare workers throughout Eastern Europe. his residency at the Natividad Throughout his life he was involved For that work, Miller was awarded the University of Illinois Medical Center in musical activities, including band Alumni Humanitarian Award in 2012. in Salinas, and orchestras in high school and After 38 years with Kaiser, Miller bypassed retirement and he began college as well as church choirs. ventured into private practice before Simi Valley Hospital in Simi his private Hamilton also enjoyed University of Valley, California, recruited him to spearhead the creation of its practice. Illinois sports, camping, his annual NICU in 2008. Miller, then in his early 80s, served as the unit’s Halfpenny fishing trip to Canada with family first medical director. joined the and friends, and telling jokes. He “I don’t have money to buy a hospital, so giving of my Salinas Valley was preceded in death by a son knowledge is what I do,” Miller said of his commitment to Memorial and is survived by three daughters educating others. Healthcare from his first marriage, as well as Norman Halfpenny A Renaissance man whose initial email address started System’s his wife, Linda, a stepdaughter, with “hyperAl,” Miller also played the violin and was a founding medical staff in 1961 and went to 10 grandchildren and eight great- member of the Los Angeles Doctors Symphony Orchestra. “Dr. emeritus status in 2003. He retired grandchildren. Al,” as many knew him, also devoted his summers to Camp from practice in 2005. Halfpenny’s Hess Kramer in Malibu, California, where he served as camp two great pastimes were golf Jules Shapiro ’59, physician. and flying. He owned a low-wing MD ’61, Res ’66, — Daniel Smith Comanche airplane that he and his died on Aug. 19, second wife of 38 years, Suzen, used ’61 2017. Shapiro was to fly to Chicago. an orthopaedic surgeon, educator, inventor and sculptor. He specialized footsteps as a physician—as well he began a long and distinguished David Hamilton in surgery of the hand, serving as as 15 grandchildren and nine great- career specializing in anesthesiology, ’57, MD ’59, onetime an orthopaedic surgeon at Rush- grandchildren. serving as associate professor, physician for the Presbyterian-St. Luke’s Medical emeritus at Northwestern University ’59 University of Illinois Center for 31 years. The author of Donald Funk ’51, Feinberg School of Medicine. He football team, died on Nov. 1, 2017. A several scientific papers, he was a MS ’52, MD ’56, was active in the Boy Scouts of lover of music and an accomplished professor of orthopaedics at Rush died on Aug. 10, 2016, America for 75 years, serving in upright bass player, Hamilton and also inventor of the 3M Shapiro ’56 in Boynton Beach, many capacities, and he received interned in Fresno, California, Stapilizer, a machine that stapled Florida. An anesthesiologist, educator, the National Outstanding Eagle before returning to Urbana to begin bone to bone. Upon retirement, he master gardener and proponent Scout award in 2012. The 2012- his family practice with Gernon turned his love of working with his of the Boy Scouts, Funk went into 2013 Northeast Illinois Council Eagle Hesselschwerdt, MD. Hamilton hands into sculpting bronze and private practice in Walnut, Illinois, after Scout class was named in his honor. served as a flight surgeon in the U.S. stone. He lived his life by the credo: serving in the U.S. Navy, where he A volunteer at the Chicago Botanic Army, stationed in South Carolina humor, humility, humanity. Shapiro was stationed in Jacksonville, Florida. Garden, Funk became a certified and Panama, and he traveled and his wife of 42 years, Marian, had Funk later relocated to Chicago, where University of Illinois Extension Master extensively in Central and South one daughter and three grandsons.

ILLINOIS MEDICINE | 45 FOUNDING DIRECTOR OF COM NEURO- PSYCHIATRIC UNIT Moises Gaviria, MD, enjoyed a groundbreaking, three-decades- long academic career at the College of Medicine, where he established the first affective disorder clinic at the Chicago campus and served as its founding director, and he led the fellowship program in neuropsychiatry. Gaviria was a “consummate clinician and educator,” says Henry W. Dove, MD, professor of clinical psychiatry and associate dean for graduate medical education at the COM Chicago. “He Moises Gaviria taught and mentored a generation of students, residents and fellows, building bridges that they too might cross with confidence and ease,” Dove says. A founder of the International Neuropsychiatric Association, Gaviria taught locally, nationally and internationally. He worked with the Peruvian American Medical Society and numerous other organizations to enhance mental health care and education across Latin America. He was also a prolific researcher and writer, publishing more than 150 papers and co-authoring four textbooks. Gaviria was born in 1943 in Chiclayo, Peru, and attended medical school at National San Marcos University in Lima before completing his residency at the University of Connecticut and a fellowship at the Illinois State Psychiatric Institute. After retiring from the University of Illinois in 2004, he was named a Distinguished Professor of Psychiatry. Gaviria continued to teach and see patients as a member of the department of psychiatry at Advocate Christ Medical Center in Oak Lawn, Illinois, and in 2014 he moved to private practice. At the time of his death he was a faculty member at the Loyola University Medical Center in Maywood. Gaviria loved international travel with his family, spicy food, symphony concerts and The New York Times. Gaviria passed away on Sept. 9, 2017, surrounded by family and friends, due to complications of brain cancer. He is survived by his wife, Nancy; his sons, Boris, Ivan and Alex; his daughters-in-law Heidi and Terra; and his four grandchildren.

— Melissa Maleske

46 | SPRING 2018 It all starts with a single spark

Innovative

We are Illinois’ premier, public College of Medicine and we are poised like few other institutions in the nation to deliver on the promise of leadership to advance medical education, research and healthcare delivery into the future. Today, we stand at the confluence of technology, medicine, bioinformatics and engineering. The opportunities to leverage these domains to advance medicine are limited only by our imagination and investments from our philanthropic partners. Our campaign will accelerate us into a new age of medicine that is developed and delivered in every community, urban or rural, wealthy or financially-strapped, under-served or advantaged communities around Illinois and world-wide.

JOIN US AND MAKE A GIFT TODAY!

To make your gift today and start your own spark of inspiration, return a check using the enclosed return envelope OR make a gift online at www.medicine.uic.edu/givenow. Questions? Call the Office of Medical Advancement (312) 996-4470. 5 QUESTIONS

QJoe Geraghty, MD/PhD student and president of the Chicago Medical Student Council, talked to Illinois Medicine about what broughtA him here, his work in the lab of Jeffrey Loeb and Fernando Testai in the UI NeuroRepository, and his experience this year as student council president.

1 What motivated you to attend medical school and to apply for the MD/PhD program at the COM? • Growing up, I always knew I wanted to be a doctor, and I wanted to teach. As an undergraduate at SUNY Geneseo, I did research in an organic chemistry lab, synthesizing organic compounds that had different medicinal applications. It was my first opportunity to fall in love with science for the sake of science. When I visited the College of Medicine, it seemed like the program was really invested in recruiting applicants. I was encouraged by the sense of collaboration I saw. I knew it would be supportive and allow me to excel.

2 What got you interested in neurosciences, and what has your work in Dr. Loeb’s lab and the NeuroRepository involved? • Neurological diseases are so debilitating. During my second year of medical school, I met with Dr. Loeb and was immediately impressed by his enthusiasm and passion, and how his research translates to the diseases that affect his patients. Our lab studies a broad range of neurological diseases, from epilepsy, to ALS, to stroke. For my thesis project, I’m studying the role of neuroinflammation in long-term impairments after a particular type of stroke called subarachnoid hemorrhage, which occurs when aneurysms in the brain rupture. We are looking at seizure activity and cognitive dysfunction, as well as testing immunomodulatory therapies to prevent these impairments. The UI NeuroRepository has been a great addition to our lab’s research program, as we now have access to a tremendous amount of patient data, including both tissue and clinical data from patients with epilepsy, stroke and ALS.

3 What are your priorities as president of the Chicago Medical Student Council? • I’ve been able to help establish an organization known as the Student Curricular Board, a unique collaboration between student government and the Office of Curricular Affairs. I have been advocating for my peers, bringing issues regarding curriculum and student services to the attention of the administration. My central goal this year has been to take these issues and synthesize them in a solutions-oriented fashion—like through “Dialogues with the Deans” events. We have created several brand-new committees on topics like wellness and resilience, diversity and inclusion, and preparation for licensing exams.

4 How has the revived focus on the student in the revamped curriculum improved your experience and that of your classmates? • I am thrilled with the new medical curriculum (see p. 4). The integrated, systems-based approach they’re taking is going a long way. Ultimately, that’s what you need to do as a third- and fourth- year medical student: When someone comes in with swelling in their limbs, it’s not just one organ in the body that’s potentially the culprit. The other thing that’s really unique is the addition of medical colloquia and synthesis, which allows students a degree of individualization in their learning that cultivates their interests and passions.

5 What makes you most proud to be a COM medical student? My answer is pretty much the same every time I get this question: It’s really the people. The • people here are really outstanding. There’s a strong sense of community, and a strong sense of collaboration. When I interviewed here, I knew I was going to learn, grow, and be surrounded by inspiring peers and mentors who would push me to my greatest potential. PHOTO: DIANE SMUTNY

48 | SPRING 2018 SHARE YOUR SPARK Inspired, innovative, impassioned, inclusive and insightful medicine happens here. It’s always happened here.

Illinois Medicine has a proud history and a noble mission because of the contributions made by our students, professors, researchers, clinicians, alumni and donors. Your story is part of our narrative of impact and achievement. As we ignite a new future for medicine, we want to hear your own spark stories of inspiration to pursue medicine or a specialty, achievement in your career, your passion to give back, or your unconventional success in your personal or professional life.

Share with us your own spark by email at [email protected] or post your spark story to our social media pages on Facebook http://go.uic.edu/COMFacebook LinkedIn http://go.uic.edu/COMLinkedIn Twitter http://go.uic.edu/COMTwitter Nonprofit Org. THE U.S. Postage PAID UNIVERSITY OF Chicago, IL ILLINOIS Permit No. 4860 COLLEGE OF MEDICINE CHICAGO PEORIA ROCICFOllD URIIAIIA

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UIC The University of Illinois at Chicago Strategic Priorities Leveraging Our Strengths to Shape the Future

The University of Illinois at Chicago (UIC) is an acclaimed research university that supports and inspires students in an urban environment. Our strength derives from our devoted top-tier faculty and staff who share a commitment to the promise of public education, the advancement of knowledge in their scholarly fields, and the imperatives of social justice and civic engagement. Furthermore, our entire university community embraces an ethic of care for the well-being of those we serve.

While there are many public research universities, none is, like UIC, so quintessentially positioned at the intersection of research and urban life. Located in the heart of Chicago, we are on the cutting edge of scholarship and service for a rapidly urbanizing world. We also hold the distinction of being one of Illinois’ leading health care providers, with an expansive health care education and services enterprise throughout the state. We benefit from the deep relationships we have with the neighborhoods we serve, and in turn we give back by helping build and support just and sustainable communities.

Today, UIC must look ahead even as we face a widening disjuncture between contemporary demands and our institutional capacity to respond. Limited state support, increasing demands, and an ever-changing economic and demographic environment require that we become a more entrepreneurial university – an institution positioned to fulfill its public purpose despite external constraints. To do so we must leverage our strengths to shape the future, while our commitment to education, scholarship, community engagement, and social justice will continue to be our guiding principle driving UIC forward.

The following set of strategic priorities provide fresh thinking for how, over the next five years, we can leverage our strengths to shape the future by supporting our students, enhancing our reputation on a national and international stage, engaging Chicago and its communities, and operating in new ways to foster and advance innovation. While the University has always excelled, we can, and will, do even better. By pursuing these priorities, we will continue to provide our students with a high-quality public education, support the efforts of our faculty and staff, and better serve the people of our city and our state.

2 UIC STRATEGIC PRIORITIES Student Experience and Success National and International Impact and Visibility Chicago and Community Engagement Entrepreneurial University

3 4 STUDENT EXPERIENCE Students are at the center of UIC’s mission and its success. Diversity, equity, opportunity, an ethic of care, and a global AND outlook are the hallmarks of our University. As Chicago’s only public research university, we honor our commitment to SUCCESS high-quality education for all by preparing our students to be successful professionals, lifelong learners, active citizens and caring persons.

ACCESS EXCELLENCE The University’s world-class faculty mentors our students in and beyond the classroom, advances our economy and culture, and .. improves the lives of people in our surrounding communities and beyond. To ensure student access to that excellence we will promote a culture that values and rewards high-quality, innovative teaching and advances critical thinking; recognition of injustices; collaboration; and entrepreneurial mindsets among students and faculty. We will facilitate open lines of communication among students, faculty, staff, and the administration. We will enhance and coordinate resources dedicated to teaching and mentoring.

FOSTER DIVERSITY Diversity is a hallmark of the UIC experience. Life on campus will continue to reflect and celebrate human differences and affirm that diversity can make us all smarter and stronger. We will continue to cultivate an inclusive culture of diversity and a welcoming campus climate, to enhance enrollment of historically underrepresented students, and to enlist the knowledge and creativity of all students.

.... - • 6 PROMOTE SUCCESS The University’s success is defined by the success of all our students. We will continue to support students’ identities and strengths and address their individual needs. We will support and guide students during key turning points in their educational careers, and we will provide advice and guidance that is consistent and meaningful by promoting greater collaboration between academic and support services. We will promote the efficient and equitable use of technologies and facilities, from labs to common areas.

CULTIVATE POTENTIAL Identifying goals, and pathways to achieve those goals, is critical to student success on campus and beyond. We will help students identify their academic and career goals and provide them with the support they need to succeed. We will align curriculum and course scheduling to facilitate timely graduation for all students, and we will provide hands-on learning and wide-ranging career- development opportunities, including a variety of internships. We will raise private funds to continue providing financial aid to those in need. ADVANCE TEACHING Attention to the strengths and needs of a new generation of learners is critical to the experience and success of our students. We will enhance and further develop teaching practices and adopt the most successful advances in face-to-face and online pedagogy. We will encourage and reward faculty efforts to innovate teaching. We will modernize our physical and technological infrastructure to support these efforts.

ENHANCE CAMPUS VIBRANCY Student experience is also strengthened by a safe and vibrant campus environment to provide opportunities for personal and professional growth. We will maintain a safe, healthy and nurturing environment for our students to learn, live and play. We will create programs and support independent student organizations to advance opportunities for student leadership and community and civic engagement. We will upgrade and modernize our existing residence halls and build new residential capacity as needed. We will strive for excellence in our intercollegiate athletics. 8 NATIONAL AND UIC is a hub of innovation with an international reputation for excellence. As a world-class university embedded in the INTERNATIONAL civic fabric of a global city, UIC is uniquely positioned to address contemporary urban issues; to be a critical resource IMPACT for leaders seeking solutions to complex 21st century problems; and to spur social, scientific and technological AND progress. PROMOTE EXCELLENCE Increased national and international recognition of the VISIBILITY outstanding work conducted at UIC can contribute significantly to further growth of the University. We will intentionally and strategically communicate the unique contributions and success of our faculty, staff and students. We will promote our mission of deep and reciprocal community engagement and its contribution to the health and well-being of Chicago residents and regions around the state. We will promote our status as a hub of cutting- edge research and innovation that advances the University’s public purpose. We will encourage faculty and administrators to take strategic risks in order to build a culture of excellence. We will advance the standards of teaching and research of the American Association of Universities.

ENHANCE REPUTATION As a leading research institution, a minority-serving university and a statewide health care provider, UIC is a powerhouse. We will continue to work at the cutting edge of scholarship and practice for a rapidly urbanizing world. We will achieve National Cancer Institute designation and Carnegie classification for an engaged university. We will promote and support international research and collaboration, especially in the fields of global health, environmental stewardship, and economic development. As Chicago’s only public research university, we will continue to stress the importance and impact of community engagement in our mission and research.

10

SUPPORT FACULTY UIC’s continued excellence in teaching and research depends on the work and success of our faculty. We will intensify our efforts to retain and recruit top-tier faculty members committed to the mission of our University. We will continue to nurture an open and friendly environment that celebrates diversity and promotes excellence. We will improve our facilities and physical infrastructure until they are at the level that our faculty deserve. We will eliminate bureaucratic obstacles that prevent the faculty from reaching its full potential.

INSPIRE DISCOVERY UIC is diverse in ideas, people, and professions. We will foster an inclusive environment and create opportunities for our scholars, students, clinicians, and support staff from diverse disciplines to interact daily to create the serendipity that launches new ideas, inventions and advances. We will continue to promote cross- disciplinary and cross-campus collaboration to spur innovation, advance social justice and create new knowledge. We will strengthen professional advancement opportunities for staff and faculty and increase institutional support for doctoral and post-doctoral scholars. We will create new opportunities for the engagement of more undergraduate students in scholarship, creative activity and research. We will increase our international partnerships and exchanges to raise the standards and expectations of scholarly excellence across all disciplines.

CULTIVATE GROWTH The University can remain vital by continuing to expand and improve. We will increase the size of the tenure-track faculty to achieve growth in research while maintaining quality in teaching. We will create the necessary infrastructure to encourage and support large multidisciplinary scholarship and research efforts. We will consider establishing a law school grounded in multidisciplinary approaches that emphasize social justice, public policy, and diversity. We will support entrepreneurial faculty members in their commercial and economic development work.

13 CHICAGO AND Civic and community engagement are at the heart of UIC. As a university created for and by the people of Chicago COMMUNITY and Illinois, we have learned from and been transformed by the rich diversity of our surrounding communities and their ENGAGEMENT people, and we embrace our mission to transform lives.

EMBRACE COMMUNITY UIC can build upon a rich history of successful community engagement. We will continue to expand the meaning of engagement by striving for equitable, transparent, and reciprocal relationships. We will develop new collaborations between the University and communities in Chicago and regions throughout the state for the mutually beneficial exchange of knowledge and resources to create opportunities for the engagement of students at all levels. We will collect and measure the impact of community engagement, listen to our partners, conduct needs assessments and broadly communicate our results. We will exceed the criteria for the highest Carnegie classification for university community engagement. We will strive to be the most engaged public university in the nation by creating incentives both internally and in Illinois’ communities to support wider access to education.

16 CREATE PARTNERSHIPS The University can benefit significantly from new collaborations with state and city agencies, as well as the business, cultural, and arts communities in Chicago and throughout the state. We will pursue opportunities to increase engagement with the state and the city and to inform public policy and economic development through our research and scholarly work. We will extend our collaborations with and increase our presence in the Chicago Public Schools and the City Colleges of Chicago. We will explore the creation of joint academic, research and creative achievement programs with the top cultural and art institutions in Chicago. We will develop new partnerships with the business community to facilitate faculty research and student placement for internships and professional positions.

EXPAND CARE UIC is committed to continuing to provide top quality health care to all, regardless of socioeconomic status. We will promote greater alignment of the health science colleges with the UI health care delivery system to better address the needs of the communities UIC serves and increase research in the health sciences. We will expand our clinical care delivery network to more areas and create new collaborations with safety net hospitals and clinics throughout Chicago to support their operations. UI Health 0

18 ENTREPRENEURIAL UNIVERSITY Due to reduced state financial support and an ever-changing economic and demographic environment, UIC faces a widening disjuncture between contemporary demands and our institutional capacity to respond. Preparing for the future, UIC needs to adapt and change to become more entrepreneurial and build a sustainable infrastructure, while maintaining an acute focus on our mission.

INSPIRE INNOVATION The University can maintain its leading edge only if it utilizes new social, financial, and technological approaches to its own operations. We will create and support a culture of innovation within all academic, student, clinical and support operations. We will establish mechanisms for new ideas to be heard, evaluated and tested in a timely fashion to ensure that the University is primed and able to respond to emerging opportunities. We will increase incentives for faculty and staff to pursue new and expanded grant and contract funding for all aspects of research and entrepreneurship. We will expand alumni and corporate connections to take innovative ideas to scale and secure resources to sustain them.

20 DIVERSIFY FUNDING UIC can no longer depend on state support or increases in tuition revenue to secure the necessary resources for the fulfillment of its mission. We will clearly align resource allocation with institutional priorities, reduce costs, and build new public-private partnerships to address capital infrastructure needs and improve support services. We will develop new and effective strategies to increase philanthropic support.

INCREASE EFFICIENCY Innovation and excellence cannot thrive in the face of bureaucracy and without state-of-the-art support services, systems and staff. We will foster a culture of customer service and timely results in all of our internal operations. We will become even more efficient and transparent in the utilization of our resources by reducing administrative costs. We will streamline administrative, personnel, financial and support services, and reduce redundancies in our staffing structure. We will modernize the technology currently used by introducing new IT tools where needed. We will optimize the use of existing space.

21 Office of the Chancellor University of Illinois at Chicago 601 South Morgan Street (MC 102) Chicago, Illinois 60607

UIC is an equal opportunity educator and employer and does not engage in discrimination or harassment. For more information, visit uic.edu/depts/oae strategicpriorities.uic.edu

OVCR Mission… facilitating excellence in research at UIC. “The investments we have made have helped grow the research enterprise at UIC and have built a platform for collaboration and innovation in the future.”

The tradition of research excellence continues at the University of Illinois at Chicago, despite increased competition for fewer dollars. UIC ranks 66th in the most recent NSF compilations Mitra Dutta, of federal funding among US universities. Over the past five Vice Chancellor for Research Distinguished Professor, Electrical and years, the Office of the Vice Chancellor for Research has Computer Engineering been focused on transforming the research enterprise. From [email protected] strengthening our research infrastructure through improvements to facilities; decreasing administrative burden for faculty by developing a strong electronic research administration platform that includes the myResearch Portal, OPRS Live, an online IRB submission system, myDisclosures, and myPropoals which will allow online submission of funding proposals; and strengthening our Research Development Services unit to provide support to faculty in crafting competitive proposals, the OVCR has overseen numerous initiatives to help enhance our research portfolio and to pave the way for both seasoned and emerging researchers.

UIC is proud of our diversity both in our student body and our faculty but also in the types of research being conducted on our campus and throughout the world. Personalized medicine has helped us focus on the individual while a focus on social justice and community disparities has allowed our researchers to examine the communities that surround our campus and make up our University.

2 | OFFICE OF THE VICE CHANCELLOR FOR RESEARCH OVERVIEW OF RESEARCH INITIATIVES

In 2014, The Office of the Vice Chancellor for Research reviewed the research strengths available across the breadth of our campus, and, with support from the larger community, and shaped by inclusive and robust discussion, grouped those strengths into six emergent cohesive initiatives. While each of these areas alone constitutes a major research initiative, potential synergistic activities make them well suited to be aligned strategic thrusts.

Introducing these six strategic initiatives supports UICs mission objectives of addressing challenges and opportunities facing not only Chicago, but all Great Cities of the 21st century, supporting scholarship and research opportunities for underrepresented students, engaging with our communities, and creating knowledge that transforms our view of the world, and through sharing and application, transforms the world.

These six strengths are:

• Big Data • The Brain • Functional and Regenerative Materials • Personalized Medicine/Genomics • Social Justice and Community Disparities • Urban Infrastructure

Annual Report 2017 | 3 AREAS OF RESEARCH STRENGTHS

The Brain Our focus in this area is broad ranging, from identifying factors contributing to addiction and depression to providing foundational science for researchers seeking new ways to treat, cure and prevent brain disorders. Fundamental to this initiative is research focusing on neurobiological mechanisms at genetic, molecular, synaptic and systems levels. Research at these stages is crucial to identifying the pathophysiology that underlies social, cognitive and affective deficit. Our programs working at the molecular level have identified overlooked nervous system pathways which may lead to new treatments for debilitating neurological diseases including Alzheimer’s, MS, and Parkinson’s Disease. Information on nervous signal transmission may identify new treatments for stroke, heart disease as well as mental health initiatives. Our goal is to better understand the biological bases of brain disorders while developing new and effective treatments for clinical practice.

4 | OFFICE OF THE VICE CHANCELLOR FOR RESEARCH Big Data Beyond the expected predictive data analytics focus, new methods of capturing, curating, transferring, storing, sharing and visualizing data will contribute to initiatives within, outside, as well as across, these strategic thrust areas. UIC, with its well-established programs spanning health sciences, computation, bioengineering and urban infrastructure is ideally situated to seize these emerging opportunities. Our ability to use our data science tools to extract value from data is a powerful force integrating experimental studies of multiple dimensions leading to better understanding of what aggregated data can tell us. Key to this initiative is systems computation modeling used to integrate experimental studies across multiple dimensions, affecting every area of society from healthcare to business to activities of daily life. Areas ranging from genomics and systems biology through energy production and storage to cybersecurity and physical infrastructure will be impacted and improved by our ability to harvest data for new uses.

Annual Report 2017 | 5 AREAS OF RESEARCH STRENGTHS

Personalized Medicine/ Genomics Our unique, diverse community affords us the opportunity to explore the emerging field of ‘designer’ medicine across a broad range of diseases and conditions impacting both the general and the underserved populations. Bringing together our strengths in basic life sciences, bioengineering, computation and health education, coupled with our unique world class centers including The UICenter for Drug Discovery, the Biospecimen Shared Resource (Tissue Bank) and the Biomedical Informatics Core, UIC has an opportunity to support translational medical research and build a bench to bedside stream of discoveries leading to truly personalized health. This initiative will foster the transformation of diagnostic and treatment approaches, development of new technologies, delivery systems and therapies to achieve the goal of individualized healthcare.

6 | -OFFICE OF THE VICE CHANCELLOR FOR RESEARCH 0 Functional and Regenerative Materials Comprising faculty from multiple disciplines, including our nationally recognized health sciences colleges coupled with our strong engineering and liberal arts & science programs, our objective is to establish interdisciplinary teams focused on translational and applied research in systems biology, imaging science and nanotechnology. This thrust will align our broad campuswide strengths, affording us a unique opportunity to identify the next generation of medical, as well as electronic, devices or novel, more efficient energy-conversion devices. This strategic initiative leverages collaborations to develop new bio- and nanomaterials by capitalizing on UIC’s leadership role in materials/tissue synthesis and our wide range of state of the art characterization instrumentation. These materials have the potential to be used in developing better drug delivery systems, novel approaches to power generation and to build biomedical devices with the goal of improving quality of life.

Annual Report 2017 | 7 AREAS OF RESEARCH STRENGTHS

Social Justice and Community Disparities In support of our mission as a public research university centered in a diverse global city, this broad ranging initiative brings together UIC scholars engaged in promoting greater equity, inclusion, justice and sustainability. Our broad strengths in research, healthcare education and clinical practice, outreach and community engagement afford us the opportunity to focus on identifying, reducing and preventing disparities in healthcare, education, economic opportunity and civic participation. Our national prominence in providing a voice addressing societal issues including racial and gender bias, immigration, violence prevention and treatment, health outcomes research, and our world class community engagement programs have the promise to bring together researchers to address many of the problems impacting the health, education and productivity of our citizens.

8 | OFFICE OF THE VICE CHANCELLOR FOR RESEARCH Urban Infrastructure Over 80% of Americans now live within urbanized areas of 50,000 or more people. The quality of life in these regions is tied to the ability of the urban system to respond to environmental, infrastructural, organizational and human challenges of the global arena. Responsiveness to unanticipated events, including economic dislocations, natural disasters, and terrorist threats, as well as the ability to maintain our environmental standards, secure our energy needs, support economic growth and maintain our structure in competitive globalized markets are keys to our ability to survive as well as to thrive. UIC’s Great Cities Initiative provides us with the basis for commitment to supporting, expanding and improving our urban infrastructure, as well as fostering scholarship and practices reflecting and responding to the increased diversity of the US in a rapidly globalizing world. “Resilient” urban areas, will be best positioned to address environmental issues including water scarcity and security, climate change, alternative energy and food security.

Annual Report 2017 | 9 Strategic Strength Highlights:

• Convened a speed networking for the Functional • UIC partnered with the CURRENT water project, and Regenerative Materials Group to bring together a non-profit group, to coordinate city and over 25 researchers from East and West campus county resources with university researchers to begin a conversation and identify ways they may linking water research, technology development, work together to develop new materials. This event commercialization and deployment in industry resulted in 7 concept papers identifying potential and infrastructure. Significant recent efforts of this new research focus areas. initiative include: a delegation to Israel to initiate collaborations with Technion - (Israel Institute of • Planning has begun for a workshop to continue Technology) seeking solutions to global water to explore collaborations in the Functional and challenges. UIC hosted a follow-up workshop Regenerative Medicine space with the goal of to explore innovations in water technology and identifying and targeting larger program projects conservation in March 2018. for funding proposals. Many of these topics have also been featured as • The Social Justice and Community Disparities part of the East Meets West Research Mixer Series Group is pursuing a campus-wide book project and involved faculty from all disciplines across envisioned as an innovative anthology focusing on campus. how we see, understand, explain and participate in the city of Chicago. We see this collective effort as a way for UIC to reshape the “Chicago School” for the 21st century.

10 | OFFICE OF THE VICE CHANCELLOR FOR RESEARCH 0 STUDENT RESEARCH FORUM

“Companies are constantly looking, so it’s important for applicants to know and watch what they’re posting.”

Neuroscience major Maribel Heredia studied how hormones like estrogen mediate the effect of anoxic depolarization in strokes. “Males and females are affected differently by strokes,” she said. “That’s why we’re looking at whether estrogen is implicated in this process. Maybe because of estrogen, females More than 300 students filled the UIC people,” said Allen, a junior in the have a better outcome than males do.” Forum April 3 to communicate — in College of Engineering. Her research just a few minutes — the importance showed how acoustic metamaterial Senior Yazan Issa said he was of their months and years of work to could be used to better monitor the proud to present his research on the faculty, alumni, staff and community structural health of pipelines. “It’s presence of Thioflavin S plaques in members. been an interesting process, going the twitcher mouse model of Krabbe through everything that I’ve worked disease — a fatal and degenerative The Student Research Forum allows on.” disorder — with a focus on the spinal undergraduate, professional and cord and the peripheral nervous graduate students to talk about their “Such beautiful diversity in system. research experiences. This year, it backgrounds and research topics. was combined with UIC Impact Day, The world looks brighter for me today “I love the research, I love solving the an event that celebrates students knowing that such wonderful young puzzle and finding the data,” he said. and their scholarly pursuits in and “It’s a way to do work that means a people will be in charge.” outside of the classroom. A total of lot to you, and, at the same time, you –Alumni judge 435 faculty, alumni and others served know that it can really benefit a lot of as judges. people.” Amaalyah Wilson, a student in Margaret Allen said presenting any business management, shared her research or other impactful student findings on how social media affects experience is important. recruitment and selection of job candidates in the hiring process. “It’s nice being able to show something that sounds pretty “Seventy percent of applicants don’t complicated and trying to explain it in get hired based on their social ways that make more sense to other networking websites,” she said.

Annual Report 2017 | 11 GRANTS AND CONTRACTS JOINS OVCR

In July 2017, the Office of Grants and Contracts officially became part of the Office of the Vice Chancellor for Research. The Office of Grants & Contracts (GCO) at UIC supports University faculty and their departments in the administration and expenditure of sponsored project awards by developing and disseminating policies and procedures, managing the financial interactions with sponsors, and assuring compliance with University and sponsor policies, while minimizing the administrative burden on faculty and protecting the interests of the faculty and the University.

The primary services of the UIC Office of Grants & Contracts include:

• Sponsored project post-award financial management – setting up and closing out awards, submitting reports and bills to sponsors, and reviewing sponsored project expenditures

• Audit and compliance – responding to audit requests and ensuring awards are managed according to applicable policies, procedures, and laws

• Cash and receivable management – collecting outstanding payments from sponsors for expenses incurred

• Costing, training and analysis – developing F&A (indirect cost) and fringe benefit rates and calculating and/or reviewing service center rates to ensure compliance with Federal guidelines; training and outreach activities; and financial analyses, surveys and reviews

12 | OFFICE OF THE VICE CHANCELLOR FOR RESEARCH • AAALAC AND AAHRPP

AAALAC UIC’s Biologic Resources Laboratory (BRL) has been continuously accredited by the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) since 1970.

The following items were recognized by the site visit team visit as program strengths:

1). An engaged and knowledgeable IACUC and IACUC office.

2). Excellent institutional communication between the animal care staff, veterinary staff, research staff, IACUC and IO.

3). The cleanliness of the facilities including both animal rooms and support areas.

4). The high level of veterinary care the animals receive.

5). The institution’s peri-operative care program and post- operative monitoring program.

A successful AAALAC site visit does not occur in a vacuum, but represents the hard work of many individuals including the animal care staff, the veterinary technical staff, the research community and the IACUC. AAHRPP The UIC Human Subject Protection Program (HSPP) has received full Association for the Accreditation of Human Research Protection Programs, Inc. (AAHRPP) reaccreditation. This accreditation is an important designation that reflects the highest quality by which the UIC OPRS and HSPP operates. The purpose of engaging in the accreditation process is to evaluate the ethical, regulatory and quality standards for human research. The AAHRPP seal places UIC among the world’s most respected, trustworthy research organizations. AAHRPP site visitors were very complementary of the research knowledge and commitment of UIC investigators and support staff to conduct high quality human research.

Annual Report 2017 | 13 GET STARTED WITH START myRESEARCH

Over the past three years, OVCR, in partnership with submission and approval process, ultimately making AITS and UIUC and UIS, as well as through in-house the overall proposal submission process more effective development, has worked to develop electronic systems and modernized. The START project team is making designed to reduce the administrative burdens of modifications to open source Kuali Research to better fit managing faculty research and increase productivity. As the needs of research administration across the University we have grown in complexity as a multi-campus research of Illinois System. institution, our technology environment was not adequately fulfilling the needs of our faculty, administrators, and myResearch Portal displays a variety of sponsored support personnel. Regulatory requirements, financial research information in a clean, user-friendly interface that pressures, and operating constraints increased the allows faculty and business managers to easily view or administrative burden for faculty and staff, and the download data to aid in their grant management activities. supporting infrastructure had not adequately kept pace. In Research administrators and principal investigators order to alleviate these burdens, a number of applications can download helpful current and pending support have been developed. information, use advanced searching and filtering to quickly get to data, and view the up-to-date status of START myResearch Applications negotiations and attachments. The myResearch Portal will This project’s efforts are towards modernizing and be getting an updated user interface, coordinating with streamlining the research enterprise at University of the release of myProposals in 2018. Illinois and reducing the administrative burden for faculty and business office staff, ultimately saving the University START myDisclosures is the electronic conflict of interest money and ensuring that we are fulfilling our financial, (COI) application that replaced paper-based RNUA and legal, and ethical obligations. The START myResearch Sponsor Specific COI disclosures. We have converted the related applications include myResearch Portal, START nearly 16,000 annual RNUA paper submissions to online myDisclosures, and use of myProposals. submissions with automatic electronic routing for approval. We have also converted the paper-based significant Sponsored Programs leverages open source Kuali financial interest (SFI) and management plan to a web Research for pre-award and grant management. Central based system. offices currently take proposal information in through the existing manual process and enter data into myProposals myFCOI Checklist is a newly released application, to more effectively manage and report on sponsored grant developed by U of I System Office AITS, that allows users data. The upcoming release of myProposals (Routing and to create checklists that will look at START myDisclosures Aproval) will streamline the manual process of submitting applications to provide the status of the checklist key proposals electronically to the central office and reduce personnel’s financial conflicts of interest (FCOI) and overhead of manually entering data into the system. training. The myFCOI checklist is also unique in that it will allow affiliates (i.e. non-University personnel) myProposals will allow investigators and business to access checklists as well as training and sponsor managers to submit sponsored proposals electronically specific questionnaire through the START myDisclosures for central office review and route them electronically application. for approvals. This will help to streamline the proposal

14 | OFFICE OF THE VICE CHANCELLOR FOR RESEARCH 0 001 \;~in~',\!' myResearch Portal [;} [ID ? Q. Loo romouo EOOI[ Rf PORTS HUF SU.ml

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OPRS Live Electronic submissions of IRB protocols These online tools not only save time for researchers became a reality in 2016 when OPRS Live was rolled out but encourages them to work with colleagues in other to the campus. This application was developed by OVCR fields and to establish multidisciplinary collaborations by IT staff in collaboration with OPRS staff members along working together on proposals. with feedback from investigators and coordinators. We continue to roll out enhancements to the system based on feedback from users to make the system as user friendly as possible. To date, over 8000 applications have been submitted through OPRS Live and turnaround times continue to decrease.

IACUC/BRL Systems in Development – The OVCR IT team is currently developing an on-line IACUC submission process which will allow investigators to submit animal protocols electronically. In conjunction with this, we are working with the Biologic Resources Laboratory (BRL) to create an on-line system that will include animal census, ordering and billing, allowing investigators to access all information via one portal.

Annual Report 2017 | 15 $4.2 MILLION FEDERAL GRANT ESTABLISHES CENTER FOR WORKER HEALTH AT UIC

The University of Illinois at Chicago School of Public Health center is one of six NIOSH Centers of Excellence for Total received a five-year, $4.2 million federal grant to establish Worker Health. the UIC Center for Healthy Work. Center investigators expect their work will contribute to Funded by the National Institute for Occupational Safety changes in local, state, and national policies and laws that and Health, the Center for Healthy Work will focus promote jobs with healthier working conditions and more on improving the health of people in low-wage, often people having fair employment and decent work. hazardous, precarious employment situations. The UIC

Dr. Martha Daviglus Jesus Ramirez-Valles Dr. Robert Winn

16 | OFFICE OF THE VICE CHANCELLOR FOR RESEARCH • RESEARCH SNAPSHOT

$8 million grant to reduce tobacco use in high-use countries

Bloomberg Philanthropies awarded the University of Illinois at Chicago $8 million to accelerate the development of effective tobacco tax systems in low- and middle- income countries.

As a new core partner, UIC joins six other global health organizations in the Bloomberg Initiative to Reduce Tobacco Use, a nearly $1 billion program to reduce the worldwide demand for tobacco through comprehensive, evidence-based policy reform and public awareness campaigns. The Bloomberg Initiative has made significant progress over the past 10 years in many areas, such as smoke-free air policies and graphic health warning labels.

Frank Chaloupka

Annual Report 2017 | 17 RESEARCH SNAPSHOT

Naked mole-rats turn into plants when found that they released large amounts of fructose into the bloodstream. The fructose, the scientists found, was oxygen is low transported into brain cells by molecular fructose pumps that in all other mammals are found only on cells of the UIC researchers have discovered that, deprived of oxygen, intestine. naked mole-rats can survive by metabolizing fructose just as plants do. The naked mole-rat is the only known mammal to use suspended animation to survive oxygen deprivation. The Understanding how the animals do this could lead scientists also showed that naked mole-rats are protected to treatments for patients suffering crises of oxygen from another deadly aspect of low oxygen – a buildup deprivation, as in heart attacks and strokes. of fluid in the lungs called pulmonary edema that afflicts mountain climbers at high altitude. In the new study, the researchers exposed naked mole- rats to low oxygen conditions in the laboratory and 18 | OFFICE OF THE VICE CHANCELLOR FOR RESEARCH • Soon, there were seven such clinics “Newly diagnosed people could have around the city, including some picked up the virus from someone that operated out of the School of who has been in treatment and had Public Health’s Community Outreach developed resistance to certain drugs, Intervention Projects (COIP) clinics. so it’s crucial that people get tested Together, the clinics serve more than so that we can prescribe the most 1,200 people each year. effective therapies,” Novak said. “Before these trials, medication was prescribed Novak was also a site principal without consideration of resistance, but investigator on several landmark these practices could actually worsen national trials that changed the outcomes. Screening for resistance way physicians thought about HIV remains the standard of care today. transmission and care. The SMART trial, With more and more treatment options which looked at giving HIV therapy coming onto the market, resistance has continuously versus periodically become less of a problem.” interrupting treatment to prevent the Changing how doctors development of resistance, found Novak continues to focus on preventing think about HIV that continual treatment was more the spread of HIV and has recently transmission, care effective at keeping viral counts low. begun recruiting participants for a The START trial found that starting clinical trial to compare the efficacy of antiviral treatment right away was a newly developed injectable drug to Richard Novak has been working to better at preventing the development prevent new infections of the HIV virus identify therapies and vaccines for HIV of both HIV-related disease as well as versus Truvada, the only FDA-approved since the 1980s, when the infection non-AIDS complications, such as heart drug currently available to prevent the first started making the news as it disease and cancer. spread of HIV. spread among the gay community. “Without these important studies, we He’s also begun to focus on another Novak was a young assistant professor would not have realized the importance sexually-transmitted infection: syphilis. of infectious disease at UIC when of early, consistent treatment in “We’re seeing an explosion in the he pushed for the hospital to open preventing worsening of disease,” said number of syphilis cases, in part a dedicated HIV clinic because the Novak. because men are more comfortable general infectious disease department having unprotected sex now that they wasn’t able to handle the influx of He was site lead investigator on are taking medications to prevent HIV HIV patients. That clinic opened in another study that highlighted the infection, so other diseases that we 1989, and just a few years later, importance of testing newly diagnosed haven’t seen in a long time are making Novak received funding to open UIC’s patients for drug resistance before a comeback.” first dedicated HIV treatment and starting them on antivirals. prevention clinics in the community in 1992.

Annual Report 2017 | 19 RESEARCH SNAPSHOT

adults — cancer, cardiovascular and advance the use of precision medicine respiratory outcomes related to various by gathering data from at least 1 levels of arsenic.” million people in the United States. Any adult who has received care at She’s also studying the early life health UI Health’s hospital or clinics can effects of arsenic exposure in children participate in the study and so far, more who live in Bangladesh. than 300 patients have enrolled at the site, Argos said. “We are following them into the future to look at patterns with blood pressure, “We have a very diverse patient diabetes-related markers, growth and population that has been engaged other measures,” she said. and interested in participating, which Another of Argos’s studies on toxic very much aligns with the national metals found that people who eat a goals of the program to make sure gluten-free diet may be at risk underrepresented populations have the for increased exposure to arsenic opportunity to participate in the study,” and mercury, which can lead to she said. Examining health effects cardiovascular disease, cancer and of toxic metals in drinking neurological effects. Gluten-free diets Argos joined the UIC School of Public often substitute rice flour for wheat, Health in 2014 after working as a water rye and barley flours, and arsenic research assistant professor at the bioaccumulates in rice. University of Chicago. What are the health effects of arsenic from drinking water and other sources? “These results indicate that there could Argos teaches genetic epidemiology be unintended consequences of eating to master’s and doctoral students That’s a question that Maria Argos aims a gluten-free diet,” Argos said. “But until and advises Honors College to answer in her research studies. we perform the studies to determine undergraduates for their capstone if there are corresponding health projects. Argos examines the levels of arsenic in consequences that could be related drinking water primarily in Bangladesh, to higher levels of exposure to arsenic Students who are considering research and the associated health effects for and mercury by eating gluten-free, careers should get involved as early as people who live there. more research is needed before we possible, she said. can determine whether this diet poses “There are naturally occurring elevated a significant health risk.” “Start meeting with faculty members levels of arsenic in drinking water in and work with different faculty to many areas of Bangladesh,” said Argos, Argos is also co-investigator and get as much exposure as possible to associate professor of epidemiology program director for UIC and UI different research areas and projects,” and biostatistics. “Much of my work Health’s role in the All of Us Research Argos said. has focused on the health effects in Program, a historic national effort to

20 | OFFICE OF THE VICE CHANCELLOR FOR RESEARCH 0 believed to play a significant role in the development of Alzheimer’s disease and other neuroinflammatory disorders. Fish oil capsules are marketed based on the idea that supplementing DHA by taking the capsules will replace DHA lost or degraded in the brain. But Subbaiah has found that the form of DHA in these supplements does not cross the blood-brain barrier.

“DHA in fish oil can be absorbed by other organs of the body where it is beneficial, such as the heart and liver, but it can’t get into the brain to have any neurological or neurocognitive effects,” Subbaiah said. “There is another form of DHA called lyso-PC that can cross the blood-brain barrier, and we have shown in mice that we can increase DHA in the brain by about 100 percent when we feed mice Does fish oil improve diseases, atherosclerosis and lyso-PC for one month at low tolerable metabolism. doses.” mood, cognitive function? But he is most excited about the direction of his current research, which Subbiah’s mice fed lyso-PC also “I’m a lipid biochemist,” said Papasani suggests that the fish oil capsules performed better on tests of memory. Subbaiah, professor of medicine in the many people take to improve cognitive He hopes to determine the effects department of diabetes/endocrinology function and mood may not provide the of lyso-PC in a mouse model of and metabolism in the UIC College of benefits promised. Alzheimer’s disease. Medicine. The main active ingredient in fish oil “This isn’t a drug,” said Subbaiah. “It’s Subbaiah’s career has focused on capsules is omega-3 fatty acids, which a dietary fat that represents a novel analyzing the role of lipids — the can take two different forms, one of way to get DHA into the brain, and it molecules that make up fat in the which is docosahexaenoic acid, or could have a big impact on preventing body — for more than 40 years. His DHA. DHA is present in the brain and or treating Alzheimer’s and other brain contributions have added to knowledge acts as a powerful anti-inflammatory disorders.” in several fields including Alzheimer’s agent, but over time its function disease and other neuroinflammatory wanes. This deterioration in function is

Annual Report 2017 | 21 RESEARCH SNAPSHOT

While protein-protein interactions may breast cancer growth using stapled be more challenging drug targets, “they peptides in vitro —in petri dish cells. are ubiquitous throughout the cell, and targeting them may be more impactful Moore and his collaborators are also if we can develop ways to manipulate studying another protein in vivo—in their activity,” Moore said, “especially living organisms. This protein, called when it comes to conditions that lack Nrf2, controls expression of protective adequate pharmaceutical treatment enzymes of cells and is an important options or for conditions that are drug target for many different known to become resistant to small conditions; Moore is investigating ways molecule drug therapies.” to activate Nrf2 for chronic wound healing. For example, Moore’s lab is investigating a protein-protein “Chronic, non-healing wounds of the interaction to treat estrogen receptor- skin are serious medical complications positive breast cancer. that affect over 6.5 million Americans,” Designing a new class of Moore said. “While there are surgical prescription drugs “Estrogen receptor-positive breast and topical treatments for these cancer is known to become resistant to wounds, which include pressure sores Terry Moore is a medicinal chemist the endocrine therapy drugs currently and diabetic foot ulcers, there are focused on discovering new drugs to used, like tamoxifen,” Moore said. “When almost no pharmaceutical therapies, improve the lives of men and women that happens, physicians have very few and the high number of lower-limb living with chronic health conditions, treatment options left to offer patients. amputations each year arising from like cancer and diabetes. “Our approach targets a different these wounds provides undeniable surface of the estrogen receptor with evidence that new treatments are Unlike many drug discovery labs, a novel design strategy,” said Moore, needed.” Moore’s lab investigates the way that whose lab has created a series of new proteins interact with one another in “stapled peptides.” Stapled molecular Moore hopes that, by studying protein- diseases. structure causes these peptides to protein interactions and developing degrade at slower rates, not unlike the tools needed to harness their “Proteins interact over large surface many small molecules, and more easily therapeutic potential, his lab will pave areas, usually much larger than the permeate the cell to affect the function the way for the development of a new interactions of proteins and small of the estrogen receptor. class of drugs. molecule drugs, like statins or corticosteroids,” said Moore, assistant Already, the stapled peptides have “We want to create something new,” professor of medicinal chemistry in the worked in biochemical models. Moore Moore said. “Something that may help UIC College of Pharmacy. “This makes and his collaborators are now studying people.” these protein-protein interactions more inhibition of estrogen receptor-positive difficult to target.”

22 | OFFICE OF THE VICE CHANCELLOR FOR RESEARCH 0 person,’ and it really washes kids out of Her research—which has garnered the pipeline before they really get in it,” more than $30 million in grants and Lawless said. contracts during her time at UIC and has led to more than 50 referred Among her current research projects, journal articles and book chapters she is serving as the principal in the past 10 years alone—focuses investigator on two collaborative on educational technology with an projects between UIC and the emphasis on seventh-grade and University of Connecticut that focus on eighth-grade students. using technology mediated, problem- based learning simulations to capitalize While many in the United States believe on the multidisciplinary nature of social that as a nation, not enough students studies to learn and apply science. are going into the fields of science, technology, engineering and math The project calls for students to use (STEM), Lawless believes we have a technology to communicate and work Giving middle school secondary and potentially more critical with each other to come up with students the tools for issue facing our nation —the need for a solutions to real issues threatening scientifically literate citizenry. the world, including global climate success change as well as water and food “I want all kids to walk away with some scarcity issues. The project, which Kimberly Lawless, associate dean for fundamental principles of scientific has influenced the learning of 7,000 research in the College of Education, literacy and being able to argue from students as well as their teachers, has believes that science literacy is a evidence and being able to ascertain led to benefits to all the students, but tool, and like any tool, be it a hammer, the difference between real data and especially among students in urban screwdriver or wrench, you need to opinion data,” Lawless said. settings. learn what it is, what it does and when to use it. Her research focuses on leveraging “I want kids to love learning again and technology to integrate science I want them to understand that having “If you go through the world thinking education into the humanities, such the fundamental tools of scientific that you only have a hammer, the only as social studies. She focuses much literacy are tools that they can leverage thing you can do is hammer,” said of her research on how teachers can for their use in their lives,” said Lawless. Lawless, professor of educational use technology and real-life examples psychology. “But if you go through life from their communities to keep their “Knowing that this community that with a complement of tools and you students interested in science. I work in values what I do and sees are able to fluidly mix and match those that it’s supporting the mission of the tools to the job that’s in front of you, “Something around upper middle university, makes my everyday job even you’re going to better accomplish the school happens and then they’re, ‘I’m better than it already is.” job.” not a math person, I’m not a science

Annual Report 2017 | 23 RESEARCH SNAPSHOT

“I have been able to watch it grow Davis, a distinguished professor in LAS, into something that now is not says most people grow up thinking of only nationwide, but getting to be disability as a problem other people international,” said Davis, professor have, rather than as part of the life of English, disability and human cycle. development, and medical education. “It is one of those fields where activism “It’s a word they want to stay as and intellectual work go hand-in-hand.” far away from as possible and the experience of disability,” he said. “Most His 2015 book, Enabling Acts: The people are not that familiar with it and Hidden Story of How the Americans yet it doesn’t take long to get people with Disability Act Gave the Largest up to speed.” US Minority Its Rights, which detailed the landmark legislation’s history and Inspired by the interaction between far-reaching influence, was nominated disability and poverty, he has been for the Pulitzer Prize and the National working on a project about the Enhancing public Book Award. representation of poverty in literature, knowledge of disability film and culture. His contributions to the field were also studies recognized when Davis was among “In general, of all the identity groups, a select group of scholars, activists poor people really don’t have an Lennard Davis began his career and legislators invited to join former opportunity to represent themselves,” 40 years ago, studying the history President Barack Obama at the White he said. “Almost everything we have is and origin of the novel, but later House’s 25th anniversary celebration written by people who are not poor. transitioned to an underdeveloped area of the act’s passage. Some disabilities are still kind of like of work called disability studies. that, too.” Overall, his impressive scholarly Since then, his renowned research, production includes six books, seven Whether it’s at the British Library, the books and essays have elevated the edited collections, two memoirs, a Wellcome Library or Newberry Library, field, enhanced public knowledge novel and a monograph on 18th- Davis enjoys conducting archival and made society reconsider its century literature. research and calls it a crucial part of assumptions about normalcy, including humanities work. issues of race, class, gender and His editorship of The Disability Studies sexuality. Reader, now in its fifth edition, has “It’s important for us to remember established the advanced collection our history and delve into it because Today the Guggenheim and Fulbright of essays by scholars from multiple it’s so easy in this era to forget about award-winner is widely considered disciplines as an essential classroom facts and just go with whatever you are one of the founders and leaders of text. thinking or feeling,” he said. disability studies.

24 | OFFICE OF THE VICE CHANCELLOR FOR RESEARCH 0 to happen next,” she said. “What makes rates may be affected by multiple this possible is having a lot of data.” factors including the location of health Cruz is collaborating with the Chicago centers, temperature, rainfall, type of Department of Information Technology landscape and population distribution.” to help implement the “OpenGrid” initiative. She’s helping to integrate She developed her interest in large datasets published on the city’s databases while in graduate school at online portal. the University of Toronto, where she received her Ph.D. in 1994. “Chicago has been a leader in making data public and publishing it online “I was fascinated by data modeling,” —and that’s no minor achievement,” she said. “What brought me to big data she said. “The next step is how to put was that it involved a lot of practical Finding patterns to make together different datasets.” research — real projects like working sense of complex data with the city. While in graduate school, The city publishes, for example, data on I developed the first graph query Isabel Cruz makes sense of complex health inspections at establishments languages, a subject that is of great data. that serve food—restaurants, day cares, importance now because of social and other businesses. “They will revisit networks. That work still gets many “One of the aspects I work on is businesses that have failed previous citations.” heterogeneous data—for example, how inspections so it is very important to to make sense of data that is collected put the data together so that we can She joined UIC as an associate with different spatial and temporal see if the businesses have had other professor in 2001. She became a full granularities,” said Cruz, professor of registered names, how long have professor in 2009. computer science. they been there,” she said. “There are thousands of businesses in the city What has kept her at UIC for 17 years? The U.S. Census, for example, collects and there are all kinds of aliases for data every 10 years, but other businesses. Putting all this together “I love working with my students. They population data within a city may be helps inspectors know where to go are the best and really keep me going,” taken every month or year. next.” she said.

Her job is to use semantics so that Last summer, Cruz was named a Grand “What brought me to UIC was the data make sense when put together. Challenges Explorations winner, an strength of its research, especially in initiative funded by the Bill & Melinda database and information systems. Through her research, Cruz extracts Gates Foundation. It had and it has very well-known patterns from big data to perform researchers, and now it’s an even predictive analytics. “In order to eliminate malaria, we need stronger group in terms of big data and to be able to accurately monitor the data science.” “If you understand patterns, then you changing patterns of infection across may be able to predict what is going an entire region,” Cruz said. “Infection Annual Report 2017 | 25 RESEARCH SNAPSHOT

Incorporating regulated by or held accountable to Pharmacy. “This is about advocating any of the groups that provide checks for accountability that reduces health pharmacies, essential and balances for other essential health disparities and prevents harm to the medicine in policy services, like care in hospitals and public.” clinics. For more than 10 years, Dima Qato For example, Qato’s research has worked as a retail pharmacist and Through research, Qato wants to draw found that people living on the South witnessed countless examples of the attention to the significant public and West Sides of Chicago are more vital role pharmacies play in the public health risks associated with unchecked likely than others in Chicago to live in health system, particularly when it retail pharmacy practices and the a pharmacy desert, which she defines comes to access to and safe use of potential for pharmacies to help as living more than one mile away from medications. provide solutions. a pharmacy or, in cases where there is no access to public or other means However, while many like Qato “This is not a criticism of pharmacies,” of transportation, a half-mile from a consider pharmacies to be an essential said Qato, assistant professor of pharmacy. part of our health care system, the pharmacy systems, outcomes independent and chain retailers are not and policy in the UIC College of 26 | OFFICE OF THE VICE CHANCELLOR FOR RESEARCH • “For many people, medication is Pharmacies also play a significant role challenge is that this is not a regulated essential to maintain health — both in helping patients to manage their practice,” she said. physical and mental — and the ability medication and use it safely – or at to go about daily life,” Qato said. “But least they should, Qato said. Qato hopes her research provides the in many communities, people simply evidence needed for the creation and cannot get the medication they need, “I also study national population-based evaluation of potential public policies not only because of money, which is, medication data,” she said, “to identify at local, state or federal levels. and has always been, the focus of most common medication combinations, or policy efforts to make prescription medication-supplement combinations, “My research is about ensuring people, drugs affordable, but because their that might put patients at risk of regardless of where they live or who local pharmacy has closed or there is experiencing an adverse event due to they are, have access to essential no local pharmacy.” the interaction of drugs.” medicines. It’s about understanding and improving the safe use of Qato said that despite the growing Findings from Qato’s research, which medications. It’s also about making number of pharmacy deserts in has received significant national news sure pharmacies are not ignored in Chicago, the number of pharmacies media and hospital emergency room the development and implementation has not changed in recent years. attention, provides evidence that older of policies aimed at improving public adults are not only increasingly using health and reducing health disparities,” “There are plenty of pharmacies in prescription drugs, but that many are Qato said. Chicago, they are just not equitably also using them in potentially deadly distributed,” Qato said, noting that combinations. Qato received a bachelor’s degree in pharmacy deserts exist primarily in biological sciences from the University poor, minority communities. Perhaps in the future, she said, of Illinois at Urbana-Champaign, a pharmacies can improve dispensing PharmD from the UIC College of “The government targets and practices and help mitigate the use of Pharmacy, a master’s degree in public funds the development of federally these dangerous combinations. health from Johns Hopkins School of qualified health centers in medically Public Health, and a Ph.D. from the UIC underserved areas, but there are no “Prescriptions often come from School of Public Health. rules or incentives in place to ensure more than one physician,” Qato said. that all communities have access to “Therefore, the prescribing doctor, pharmacies,” Qato said. “Pharmacies when making a treatment decision, may open and close largely based on not be aware of all the medications or business profitability, not local needs supplements a patient is taking. and, until there is public accountability, such business decisions should not be “As pharmacists, identifying surprising.” adverse medication combinations is an important part of our job. The

Annual Report 2017 | 27 ARMY RESEARCH LABORATORY

The Army Research Laboratory, (ARL) the Army’s Corporate Research Lab has decided to form extended and open campuses on university locations at four places. These include ARL West based in Los Angeles; ARL South in the University of Texas schools, ARL Central in Chicago and ARL Northeast in Boston. UIC is a partner in the ARL-Central initiative with University of Chicago, Northwestern, UIUC, University of Wisconsin and Purdue. Their criteria for picking these locations was a critical mass of first class research talent & infrastructure; proximity to innovation centers and potential to transition to industry; potential to use or enhance critical infrastructure; willingness of partners to host ARL staff & their collaborators; locations beyond ARL’s current regions and Ribbon cutting ceremony at University of Chicago with (from left center to right) attractiveness to potential ARL recruits. ARL Mayor Rahm Emmanuel, Senator Dick Durbin, entrepreneur Michael Polsky and Central plans to recruit a mix of Government & Army Undersecretary Hon. Ryan McCarthy ( Acting secretary then). The VCR/ non-Government people locally, including ARL VPRs of the six partner institutions or their representatives are present. staff, students, professors, and contractors. They also plan to partneras with other Government organizations.

The ARL Central Laboratory had its ribbon cutting in November of 2017 with Mayor Emanuel and Senator Durbin as well as the acting Secretary of the Army, Ryan McCormick, in attendance. The VCRs and VPRs of the partner institutions were in attendance. As the partnerships are forming the ARL scientists and engineers are visiting the universities, meeting UIC faculty and working out joint collaborative agreements for projects; the umbrella collaborative agreements and faculty, student, and postdoctoral support are being worked on. UIC – ARL Collaborative with Dr. Birdwell, (left), Dr. Amirtharaj (Right) Sensors and Electronics Directorate and Dr. Mark Tschopp, Regional Director, ARL Central (middle). 28 | OFFICE OF THE VICE CHANCELLOR FOR RESEARCH • UIC is an integral part of Chicago, a world-class city. With a student population of 30,000 students representing the diverse demographics that mark Chicago as a major contemporary urban center, UIC is Chicago’s largest university. Within UIC, the OVCR operates to enable faculty, research staff and students to conduct programs of research and inquiry of the highest standards to meet our mission as a public research university.

OVCR Resources…for faculty and research staff

CONFLICT OF COMMITMENT AND INTEREST (COCI) External activities can lead to conflicts of commitment or interest with regard to one’s university responsibilities, the non-university activities must be measured and monitored. The COI office will help you to disclose and manage conflicts arising from your non-University activities. In FY17, the COCI office processed 7351 reports of non-university activities and 1313 sponsor specific disclosures. Contact: [email protected]

OFFICE OF ANIMAL CARE AND INSTITUTIONAL BIOSAFETY (OACIB) OACIB provides regulatory oversight, education and guidance on the use of animals, recombinant DNA, and infectious agents. OACIB assists investigators in complying with governmental and university policies regarding the use of animals in research, testing or teaching and in research that involves the use of recombinant DNA and infectious agents. In FY 2017, there were approximately 300 protocols submitted and reviewed. There are currently almost 800 active protocols involving animals used in research, testing, or teaching and 200 active protocols involving rDNA and/or infectious agents or toxins. Contact: [email protected]

OFFICE OF GRANTS AND CONTRACTS (GCO) The Grants and Contracts office is responsible for supporting University faculty and their departments in the post-award administration and expenditure of sponsored projects by developing and disseminating policies and procedures, managing the financial interactions with sponsors, and assuring compliance with University and sponsor policies, while minimizing the administrative burden and protecting the interests of the faculty and the University. In FY 2017, there were 2902 Chicago grants with expenditures. Contact: [email protected]

OFFICE FOR THE PROTECTION OF RESEARCH SUBJECTS (OPRS) The Office for the Protection of Research Subjects (OPRS) provides administrative support for the review and approval of research protocols (experiments) involving humans and human embryonic stem cells (hES). OPRS helps ensure that regulations are adhered to for the protection and welfare of subjects, investigators, and the University. In FY 2017, there were greater than 7,900 submissions. There are currently 3,200 active protocols. Contact: [email protected]

Annual Report 2017 | 29 OFFICE OF RESEARCH DEVELOPMENT SERVICES (RDS) RDS disseminates funding opportunity information to the UIC community and provides expertise for Community of Science. RDS offers policy guidance and assistance in seeking external grants, provides training and assistance for center and program grants, and facilitates the Campus Research Board and other seed grant initiatives. RDS coordinates the campus-wide selection of proposals for limited submission opportunities and enables efforts to develop new research initiatives. Contact: [email protected]

OFFICE OF RESEARCH SERVICES (ORS) ORS handles all pre-award and non-financial post-award activities. Pre-award activities include activities from the pre-proposal stage to the receipt of the award, up to the point of account set up. ORS assists faculty and staff in interpretation of sponsor guidelines, development, review and endorsement and submission of proposals. Non-financial post-award activities include the acceptance of the award, negotiation and execution of contracts, reporting, receipts and processing of the Notice of Awards (NOA), all communications with the sponsor of changes such as requests of no cost extensions, changes in scope or of investigator and transfers while ensuring compliance with both agency and University policies. ORS also develops and communicates institution-wide policies. ORS has processed over 3,800 research proposal applications and greater than 1,500 awards and contracts during FY 2017. Contact: [email protected]

RESEARCH INTEGRITY (RI) Research is a central and highly valued element of the mission of the University of Illinois at Chicago. As such, priority is placed protecting the integrity of the research conducted at UIC. In the event that allegations of research misconduct are reported, OVCR is responsible for implementing the established procedures for impartial fact finding that leads to the fair adjudication of the allegations. OVCR fosters Research Integrity campus-wide by contributing to those educational efforts of departments, colleges and schools related to the Responsible Conduct of Research. Contact: [email protected]

RESEARCH SERVICE UNITS

BIOLOGIC RESOURCES LABORATORY (BRL) BRL is the centralized animal facility at UIC. The staff of the BRL oversees the procurement, care, and maintenance of animals used in the research, teaching and testing programs conducted at UIC. This includes ensuring that the UIC animal care program meets federal regulations, the requirements of AAALAC, and currently accepted standards for providing adequate veterinary care and proper animal husbandry. The professional staff is also responsible for consulting with research and teaching staff, conducting graduate and technical courses, directing the postdoctoral training program, and supporting the protocol review system of the institution’s IACUC, the Animal Care Committee (ACC). The average daily census for the BRL in FY 2014 was 27,935, in FY15 it was 29,614 and in FY16 it was 38,694, and in FY17 it was 40,078. Contact: [email protected]

RESEARCH RESOURCES CENTER (RRC) RRC maintains and supports high-technology scientific equipment for use by research faculty and staff. RRC personnel provide user access to the instruments, training on use of the instruments, and their own service and expertise in the application of the equipment for the purpose of solving of a wide range of problems for chemical, biological and structural characterization. In addition, the availability of computational and statistical services for data handling, interpretation of experimental results and data transfer, together with the accessibility of electronic and mechanical shops further enhance the RRC’s mission of contributing to the research endeavor at UIC. Contact: [email protected]

30 | OFFICE OF THE VICE CHANCELLOR FOR RESEARCH 0 Total Sponsored Research Expenditures by Funding Source

State 4% Other Government <1%

Private 15%

Federal 81%

• Federal Other Government • State • Non Federal

Annual Report 2017 | 31 FY17 Program Expenditures Function

Instruction 3% Public Service Scholarships & 16% Fellowships 13%

Research 68%

• Research • Scholarships & Fellowships • Public Service Instruction

32 | OFFICE OF THE VICE CHANCELLOR FOR RESEARCH FY17 Program Expenditures Source

State 4%

Other Private Government 13% <1%

Federal 83%

• Federal • Private • State Other Government

Annual Report 2017 | 33 FY2017 Awards Received by College

Urban Planning and Public Affairs 2% COM at Peoria/Rockford Business Administration Dentistry 2% 0% 2% Other* 3% Pharmacy Architecture, Design Nursing and the Arts Social Work 5% 10% 0% 1% Library Engineering 0% 10% Education 2% Applied Health Sciences 4% School of Public Health COM Chicago 6% 48% Liberal Arts and Sciences 10%

D Architecture, Design and the Arts • Applied Health Sciences D Business Administration • COM at Peoria/Rockford • COM Chicago • Education • Engineering Dentistry Liberal Arts and Sciences D Library Nursing • Pharmacy • School of Public Health • Social Work • Urban Planning Public Affairs Other*

34 | OFFICE OF THE VICE CHANCELLOR FOR RESEARCH FY 2017 Awards Received by Sponsor Type

NON FEDERAL, $77,697,487.71

DHHS, $178,639,630.02

a OHHS

a NSF a OTHER FEDERAL

a NON FEDERAL

OTHE FEDERAL, $24,532,708.15 NSF, $22,165,264.00

Annual Report 2017 | 35 :;:'

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~ ·= UI HEALTH POINTS OF PRIDE 2018

,~ UI Health 0 OUR MISSION In collaboration with our academic partners, mission of UI Health is to advance healthcare to improve the health of our patients and communities, promote health equity, and develop the next generations of healthcare leaders.

IDENTITY STATEMENT UI Health provides comprehensive care, education, and research to train healthcare leaders and foster healthy communities in Illinois and beyond. A part of the University of Illinois at Chicago (UIC), UI Health is a clinical enterprise that includes a 465-bed tertiary care hospital, 21 outpatient clinics, and 11 federally qualified Mile Square Health Center locations. With campuses in Chicago, Peoria, the Quad Cities, Rockford, Springfield, and Urbana, the health system includes the academic and research activities of the seven UIC health science colleges: Applied Health Sciences, Dentistry, Medicine, Nursing, Pharmacy; the School of Public Health; and the Jane Addams College of Social Work.

The University of Illinois Hospital and Outpatient Care Center provide care for more than PATIENTS EACH 135K YEAR MEDICINE DENTISTRY NURSING PHARMACY ACADEMICS & RESEARCH UI Health is the only academic medical APPLIED HEALTH center in Illinois with research faculty across seven health sciences colleges: SCIENCES PUBLIC HEALTH SOCIAL WORK

In FY17, UIC health science colleges received more than $234 1,800 research awards totaling more than MILLION -

Pier C. Giulianotti, MD, FACS Division Chief, Robotic Surgery

~ UI Health ~ ,~ Enrico Benedetti, MD, FACS Head, Department of Surgery ROBOTIC SURGERY As the first Robotic Surgery Center of Excellence in the United States, UI Health surgeons have pioneered more than 30 robotic surgical procedures.

TRANSPLANT SURGERY The only active center in Illinois performing small bowel transplants. The Division of Transplantation’s kidney and liver transplant programs are among the best solid-organ transplant programs in the United States.

BARIATRIC SURGERY An MBSAQIP-accredited Comprehensive Center with Adolescent Qualifications — one of just three in Illinois. NEUROLOGY & NEUROSURGERY Certified by The Joint Commission as a Comprehensive Stroke Center, providing the highest level of emergency stroke care 24/7.

BREAST CANCER A comprehensive program combining Radiology, Oncology, Obstetrics & Gynecology, and Surgery to deliver complete care from diagnosis through survivorship, with programs dedicated to genetic risk and fertility preservation. Ali Alaraj, MD Section Chief, Endovascular Neurosurgery

Jennifer Lim, MD Director, Retina Service

OPHTHALMOLOGY One of 15 sites worldwide and the only in Illinois to offer the Argus II Retinal Prosthesis to restore sight in patients blind from hereditary retinal diseases.

DIABETES The Diabetes Center & Endocrinology Clinic is recognized by the American Diabetes Association for Quality Self-Management Education and Support. H. Steven Sims, MD Director, Chicago Institute for Voice Care

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OTOLARYNGOLOGY–HEAD & NECK SURGERY The only academic health center in Chicago to offer the Flex Robotic System for head, neck, and colorectal surgeries.

HEMATOLOGY & ONCOLOGY The Comprehensive Sickle Call Center provides a functional cure for sickle cell disease through stem cell transplantation. Advancements in stem cell transplant have led to new treatments for other rare congenital anemias

ORTHOPAEDICS Home to some of Chicago’s top experts in orthopaedic surgery and sports medicine, including United State Olympic Committee team physicians.

Virginie Achim, MD [ Microvascular Reconstructive Surgeon

Barry Wenig, MD, FACS Interim Head, Department of Otolaryngology– Head & Neck Surgery Director, Head & Neck Surgery Program Hospital Welcome Atrium Ambulatory Surgery Center Ambulatory Surgery Center

CAPITAL INVESTMENTS AT UI HEALTH

An 18- to 24-month transition to a new electronic health record platform was begun in 2018. The multimillion-dollar project will align clinical delivery, patient communications, and billing infrastructures.

Construction of a new Ambulatory Surgery Center and Hospital Welcome Atrium are additional priorities for the health system that are underway. A11M1111 aan Hurt A II a1ln'tlo11 AIINlftHn ..... All a Dlllloll ca!ITIPICATION ---CompnbNIIM 9trok.e Cen•

PROGRAM ACCOLADES UI Health has been honored with several awards that recognize quality care, treatment expertise, and better patient outcomes.

Since 2015, UI Health has been Certified by The Joint Commission as a Comprehensive Stroke Center — the highest level of stroke certification for Joint Commission-accredited hospitals. The University of Illinois Hospital is one of four medical centers in Chicago and just 10 in the state to receive this designation.

The Bariatric Surgery Program is an MBSAQIP-accredited Comprehensive Center with Adolescent Qualifications — one of just three in Illinois.

UI Health is recognized by the American Heart Association/American Stroke Association “Get With The Guidelines” program for excellence in stroke care and heart failure treatment, and by the Blue Cross & Blue Shield “Blue Distinction Center” program for quality care, treatment expertise, and patient outcomes in Bariatric Surgery, Maternity Care, and Transplant Surgery.

The 5 East Med-Surg Team has twice been honored the PRISM Award from the Academy of Medical-Surgical Nurses. Blue Blue Distinction~ Distinction~ Center+ Center

- ~~rJJlfr'd. Premier Recm\nilion In the Specialty of Med-Surg UIHealth.Care UI HEALTH GOALS & INITIATIVES

ii~ UI Health 0 2019 2020 2021 2022 FY19–FY22 & BEYOND

FY19–21 INITIATIVES CONTINUED GROWTH & OPTIMIZATION • Implementation of FY19 PERFORMANCE GOALS CRITICAL OPERATIONAL PREREQUISITE INFRASTRUCTURE Unifying Strategic Plan • Ongoing Process Improvements MANAGEMENT PERFORMANCE • 3i Project IMPROVEMENT MEASUREMENT • Surgery Center & Specialty Clinics • Welcome Atrium QUALITY • Strategic Plan Development • Reduce Sepsis Mortality Index and Implementation • Improve Postoperative Blood Clots • Access Optimization • Reduce 30-Day Readmission Rate • Improve Patient Flow • Meet Minimum Surgery Volumes • Patient Experience • Meet ICU Physician Sta ng • Focused Quality Performance SAFETY Improvement Initiatives • Enforce Two Patient Identifiers • Documentation and • Reduce Patient Safety Events Coding Performance • Reduce Employee Safety Events SERVICE • Improve Inpatient HCAHPS • Improve Outpatient CAHPS • Improve Practitioner Engagement • Improve Employee Engagement UI HEALTH ACCESS/OPERATIONAL EXCELLENCE GOALS & INITIATIVES • Reduce No-Show Rate • Reduce LOS • Improve ED Throughput GROWTH/FUNDING OUR FUTURE PLANNING CONSTRUCT • Improve Net Revenue • Reduce Operating Cost

UI Health’s Goals & Initiatives — both for FY19 and It is our commitment to be concise about our This spring, a Planning Construct was introduced to respective operational responsibilities. In addition, beyond — are vital to our long-term capabilities and immediate goals while keeping a focus on the help clearly express what will be our focus for longer-term initiatives already underway — shown as future success. longer-term infrastructure initiatives that will be activities this year and in the coming years. Critical Operational Prerequisite Infrastructure and essential to our long-term success. Continued Growth & Optimization — will require Our annual goals provide foundational support for This construct now shows the three components specific focus during and beyond FY19. Please share fulfilling our mission to advance healthcare, improve the The organizational goals have become a part of our of our planning horizon: these with your sta as we address the coming years’ health of our patients and communities, promote health FY19 Key Responsibility Areas (KRAs) and will cascade • Management Performance Improvement activities. equity, and develop the next generation of healthcare to everyone in the organization, making them pertinent Measurement leaders. Goal setting also assists us to bring focus on to the work we do every day. • Critical Operational Prerequisite Infrastructure It also is important to note that we are beginning a improving outcomes in quality, safety, service, • Continued Growth & Optimizations strategic planning process. This will be accomplished operational access/throughput, and financial Understanding and embracing the UI CARE Values — during FY19. The results of this process certainly will performance. Compassion, Accountability, Respect, and Excellence The items shown as Management Performance impact goals in the coming fiscal years. However, this — will continue to be the expectation of how we Improvement Measurement will be a part of our FY19 planning process will not change any of the items we accomplish our daily work and interactions with KRAs. These describe how we accomplish our are designating above as vital to our ongoing • UI Health 0 patients and fellow employees. day-to-day management of the organization and our performance.