THURSDAY, FEBRUARY 7, 2019 PHOTONICS Brit Berry-Pusey walks away with it WEST• Avenda Health wins Startup Challenge SHOW DAILY Photo: George Nikitin

DON’T MISS Prism Awards celebrate the best of photonics THESE EVENTS Winners, categories The world’s first cloud AI-based handheld Smart Vision Lights’ NanoDrive TODAY. Raman spectrometer; a system that derives CloudMinds’ XI AI Raman Spectrometer (Light Sources) is an embedded technology accurate 3D measurements from 2D images; (Detectors & Sensors category) is the world’s that allows tens of amps to reach the LEDs INDUSTRY EVENTS a handheld defect gauge that sizes manufac- first cloud AI-based handheld Raman spec- of a light in 500 ns or less, resulting in a KEY LEGAL ISSUES: HAVE YOUR tured parts as easily as taking a picture on trometer with 785nm laser excitation. light that reaches its full LED power/light QUESTIONS ANSWERED, SIGN UP a phone; and the first frequency-modulat- Double Helix Optics’ SPINDLE intensity when strobing. FOR A FREE SESSION ed continuous CW lidar for smart vehicles. (Diagnostics & Therapeutics) provides un- Modular Photonics’ OMPlex (Optics & 8 AM-12 PM, So. Exhibit Level These were just some of the technologies paralleled precision 3D imaging and track- Optomechanics) devices are based on pas- PHOTONICS INDUSTRY AND that are today the proud bearers of 2019 ing, breaking through limitations in visibili- sive silica chips that increase data trans- PUBLIC POLICY UPDATE 9:15-9:45 AM, Rm. 21, No. Exhibit Prism Awards. ty to allow unprecedented study of inter- and mission rates and reach in optical fiber net- Level The eleventh annual Prism Awards took intra-cellular interactions. works. The chip multiplexes a data signal PHOTONICS WEST EXHIBITION place last night at a gala event at San Fran- Leica’s BLK3D (Imaging & Cameras) into one mode in highly multimode fiber. 10 AM-4 PM, North and South Halls cisco’s Marriott Marquis Hotel. looks like a smartphone, but under the hood, Toptica Photonics’ DLC TOPO STARTUP ALLEY Never before has the Prism Awards recog- it is a 3D measurement and documentation (Scientific Lasers) builds on years of com- 11 AM-12:30 PM, Hall E, Demo Area nized such a broad range of innovation from machine designed to deliver accurate 3D pany innovation to deliver wide tunability, For the full schedule, see the technical so many different companies from so many measurements derived from 2D images. narrow linewidth output, and hands-free program and exhibition guide or download the digital control over the 1.45μm to 4.00μm SPIE Conferences app. Some events require registration. Read daily news reports spectral range. from Photonics West online: 4D Technology’s 4D InSpec XL (Test spie.org/PWnews & Measurement) is a handheld, non-contact part defect gauge that measures manufac- tured parts as easily as taking a picture on Soft LED a phone. The device makes instant, quali- implants fying, 3D measurements of surface features p.33 on manufactured parts being evaluated. Blackmore Automotive’s Doppler Lidar System (Transportation) is the world’s first frequency-modulated CW lidar for au- tonomous vehicles. It gathers instantaneous velocity and long-range measurements of every detected point. Winners all. Wilhelm Kaenders, Toptica; Scott Keeney, nLIGHT; Alexandra Yang, CloudMinds. QD Laser’s Retissa Display (Vision countries around the world. nLIGHT’s Corona (Industrial Lasers) Technology) is a retinal projection laser eye- IN THIS ISSUE. The 2019 finalists, from small companies is a fiber laser with rapidly tunable beam wear—an optical see-through, head-mount- 04 Cassini’s success to large, are advancing technologies in the quality. The Corona provides optimum beam ed display device using a miniature laser 13 Hillenkamp winners areas of healthcare, security, transporta- characteristics for an unprecedented variety projector to draw images directly to the tion, manufacturing, scientific discovery, of processes and materials, addressing a key wearer’s retina. 23 Industry report research, and more. limitation of conventional fixed-beam lasers. MATTHEW PEACH 25 Lasers in space

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BOOTH 2151 Observe the latest developments in action at the OptoSigma Technology Demonstration Corner THURSDAY, FEBRUARY 7, 2019 | 03

Future shapes emerging CHALLENGES FACING SILICON PHOTONICS TECHNOLOGY from the quantum fog On Tuesday, industry experts gath- ly provides a lot of value in closing A leading expert in quantum technology weight, and power) is a challenge. “To have ered to discuss progress and chal- high-capacity optical links,” she said. markets is more cautious than most fu- good sensitivity, you need a big SWAP. At lenges in silicon photonics design and The industry is grappling with man- turologists, but says there’s still “plenty the cheaper scale, sensitivity is not good, fabrication. The technology, which in- ufacturing efficiency. Luxtera has been to dream about,” especially when he con- about the same as a quartz clocks. There’s tegrates infrared laser sources with able to automate much of their manu- siders telecom, atomic clocks, and R&D no big advantage,” Robin said. conventional electronics on silicon facturing processes, said Drew Guck- possibilities. “Further down the road, Atomic clocks now range from as low chips, accelerates data transmission enberger, who works at the company. there will be yet more apps for finance as $1,000 to the big ones at $1 million. to promise higher Internet speeds. After they started a new manufactur- and banking, online gaming, security, and That will form the first truly “huge market Data centers, for example, use these ing facility in China, they were able defense,” he predicts. for quantum technology … the only one chips. The chips could also serve a to match its production in their other Thierry Robin, a partner at TEMAT- that will be really commercial.” pivotal role in emerging technologies plants in just two weeks because the YS in France, serving companies like For encrypted communications, such as lidar in self-driving cars, for processes were so automated, he said. Coherent, Nikon, cryptographic key example, and as quantum computing In addition, the industry needs to Siemens, Thales, management and components. outfit chip-making machines with a and others in 18 sharing between However, technical challenges new capability to fabricate photon- countries, has re- remote parties is remain, as speakers pointed out at ics designs, which are generally less viewed current and another challenge. the panel. “In particular, no one has orderly than electronics ones. Global potential quantum “How do you figured out how to integrate a laser Foundries is incorporating free-form apps and markets. distribute the source onto the chip in a commercially design capabilities in which optical de- “Other studies key?” he asked. viable way,” said Philippe Absil of Bel- signers can draw arcs and circles that for quantum tech- Teams of human gium-based IMEC. are crucial to photonics, said Steve nology foresee bil- couriers can be His company sells photonics trans- Palmer, who works for the company. lions of dollars in employed to do ceivers that enable data rates of 50 gi- Companies are also experimenting Toptica Photonics’ Jürgen Stuhler stands the near future. We beside the DLC MDL pro, which powers key exchanges, gabytes per second and beyond. It’s with different manufacturing models. are more cautious quantum computing and optical clocks. By using tamper-re- difficult to engineer a laser based on Infinera uses a vertical integration than most. contrast he is holding a 1940s mechanical sistant hardware silicon, so companies have largely used model in which they design and fab- calculator. Photo: Matthew Peach There will not security mod- other materials, such as III-V semi- ricate everything in-house, including be many full commercial apps in the next ules, or HSM boxes, that can cost up to conductors, to make a laser. But this all hardware and software needed for 10 years, Robin told Tuesday’s Industry $80,000 each. Currently, quantum de- introduces a host of other problems, their product. In contrast, Luxtera Events audience. vices are used in time measurement and such as how to bond the different ma- uses a fabless model, in which the Huge funding is moving the sector, in synchronization systems, for example terials together while maintaining company designs chips in-house but North America, Europe, and especial- with GPS networks. cheap manufacturing costs. outsources the actual fabrication. ly China. He pointed to the 65 quantum In five years, there will be advances That’s why some companies are Speakers also pointed out that startups in the field, including PsiQ, which in measurement for integrated circuits, pursuing alternatives to silicon, such while many companies are pursuing recently raised $65 million. for currents in batteries, and for magne- as indium phosphide-based photon- monolithic integration—getting all the Main market areas are sensing, imag- tometers, gravimeters, and R&D testbeds. ics. Gloria Hoefler of Infinera, based in components on one chip—chip design ing, measurement, and communications. Robin’s full study of markets, “Na- California, talked about her company’s is extremely application-specific. Notable startups where sensors make noscale Quantum Optics,” will be available indium phosphide-based photonics, Other speakers included Doug Gill use of atomic vapors include Twinleaf and by late March on the website of the fund- where they have been able to integrate of IBM and Ashok V. Krishnamoorthy QuSpin, Robin said. ing agency, the European Commission. passive and active components onto of Axalume Inc. For atomic clocks, the SWAP (size, FORD BURKHART one chip. “Indium phosphide real- SOPHIA CHEN

In uncertain times, ‘keep your fingers crossed,’ say CEOs Four-executive panel counsels industry on how to prepare for China “softening” and tariff woes.

No strangers to stress, four top photonics Systèmes in France; and Andreas Nitze, serve, and stay ahead of the curve. market and the desires of our customers. executives told an Executive Panel how CEO of Berliner Glas Group in Germany. “In five minutes, I may be crying. It’s Third, keep a diversified customer base.” they are preparing for whatever 2019 “As CEO, a lot of my time is making not looking too good with the trade war Which market segments offer the most throws at them. sure people are feeling good, feeling like with China.” What will happen in 2019? “I potential for growth in 2019? Debbie Gustafson, CEO of Energetiq they are making a difference in the com- don’t know. I need to embrace uncertain- Said LeMaitre: “Security, safety, com- Technology, now owned by Hamamatsu, pany. That great guy who’s developing ty.” To laughter, he said: “I will give you my puter space, and gaming. And augmented said she works with SEMI, a group that everything – is he still happy?” prediction at next year’s Executive Panel.” reality is a big area for growth. There is a lobbies in Washington for settling trade Others echoed that principle. Said Le- On the China issue, LeMaitre said: sudden need for more information, and for issues with China. But how to really pre- Maitre: “Keep the really smart people at “China should be 30 to 40 percent of to- high bandwidth. Those are the top two.” pare? “You stay on top of things, you pre- your company and not going somewhere tal consumption of photonics. You can’t “As sensors get more complex, and lap- pare for growth, but act quickly as needed. else. Then you can be the disruptive one.” ignore what is going to happen there. We tops get more involved, testing is more “And we are keeping our fingers What’s the top issue you are facing? are very worried for the near future.” involved, So they will be spending more crossed,” she said with a laugh. Mottay replied: “Stay on top of inno- Asked for his key current issue, Ni- money on that side of equation. Sensors Other panelists were Yves LeMaitre, vation in photonics. We (Amplitude) are tze replied: “Cash. Make sure you have are everywhere. We see great potential chief strategy officer of Lumentum; Eric a very diversified company. I respect that enough cash in the bank. Second, is strat- in that sector.” Mottay, president and CEO of Amplitude and stay mindful of all the markets we egy: everything we do is in line with the FORD BURKHART

Photonics West: The world’s largest marketplace for photonics, optics, imaging, and industrial lasers #PhotonicsWest 04 | THURSDAY, FEBRUARY 7, 2019

High-power diode lasers One such technology is high-power diode lasers, which have seen tremendous progress as a workhorse laser in ac- ademia and industry, said Günther Tränkle of the Ferdinand Braun In- stitute (FBH) in the final plenary talk. Typically based on gallium arsenide, these lasers are the world’s most efficient, dominating materials processing. Diode

lasers, for example, pump the fiber and disk lasers used in cutting and welding. They are also crucial for the ultra- short-pulse high-energy lasers used in new particle accelerators. But such de- velopments demand better diode lasers with improved efficiency, peak power, Planets, plasmas, pulses brilliance, and emission spectrum, Trän- Photo: NASA/JPL-Caltech/ Photo: Space Science Institute kle told Show Daily. Recently, researchers at FBH have The LASE Plenary covered the whole spectrum, from Cassini’s survey of Saturn, through developed a triple asymmetric epitaxial reinforcing nuclear reactors and at-risk bridges, to powerful diode pulses. layer design for the diode structure, which provides low resistance, low optical loss, On September 15, 2017, the Cassini space- the relatively young age of Saturn’s rings; new one measures just 10 centimeters low power saturation, and a low threshold craft plunged into the clouds of Saturn, and the alignment of Saturn’s magnetic across, weighs less than one kilogram, current all at the same time. They reached completing a profoundly successful mis- poles and its rotational axis, which con- and costs ten times less, making laser record efficiencies that are 1.05 times sion that had been exploring Saturn for tradicts many theories of planetary mag- peening more accessible and affordable higher than similar, symmetric designs. more than a decade. netic fields. for a wider range of applications. Airbus, This design can be used to make more For most of the final six months before “We wrote and rewrote the books on for example, is planning to use this tech- efficient kilowatt laser bars. FBH is work- its scheduled demise, Cassini took a se- planetary systems,” Maize said. nology, Sano said. Such a device would ing with the German company Trumpf ries of risky dives between Saturn and its also be useful in factories and maintain- to design laser bars with ever increasing rings, venturing into an unexplored and Plasma peening ing infrastructure. efficiency and beam quality. potentially hazardous region – something On more Earthly matters, Yuji Sano of For example, the American Society of Researchers have also been develop- it was never designed to do. In the first the Japan Science and Technology Agency Structural Engineers said 9 percent of ing monolithically integrated gratings, LASE plenary lecture, Cassini project discussed recent advances in laser peen- the US’s more than 600,000 bridges were increasing the power per emitter by 10 manager Earl Maize highlighted the ef- ing, a technique to make materials more structurally deficient in 2017, requiring times, and doubling the efficiency. This forts to repurpose the mission. resistant to fatigue and stress. $123 billion to rehabilitate them. Cheaper technology enables diode lasers with a “We had to reconfigure a lot of the en- It works by using laser pulses to laser peening could bring that cost down, narrow and stable spectrum – suitable tire operating strategy for the mission in quickly heat the surface of a material, Sano told Show Daily. for solid-state laser pumping or sensing. the environment inside Saturn’s rings,” producing a rapidly expanding pocket of In another recent invention, Sano and Diode lasers can be combined to create Maize told Show Daily. “That was quite plasma. The sudden expansion generates his colleagues developed a laser peening powerful, efficient, and compact direct di- an engineering challenge.” shockwaves that propagate through the technique that does not require water. In ode laser systems. In one method, known Using Saturn’s moon, Titan, as a sling- material, creating permanent strain and conventional laser peening, water helps as wavelength beam combining, an ex- shot, Cassini flung itself between Saturn dislocations that strengthen the material. constrain the burst of plasma, ensuring ternal grating is used to merge multiple and its rings. A missed shot and a colli- Conventional laser peening requires sion with the rings would’ve been fatal, a special coating to prevent the intense Maize said. laser from melting or damaging the ma- Once behind the rings, Cassini flew at terial. The need for such a coating makes 75,000 miles per hour, so fast that collid- laser peening difficult for some cases – for ing with a grain of dust could destroy its example, to prevent surface stress corro- instruments. Mission operators turned the sion cracking in nuclear power reactors, spacecraft so that its antenna dish could which caused several accidents around shield it from such potential hazards. the world in the 1990s. On Cassini’s other side was Saturn’s Not only are nuclear reactors radio- atmosphere, which could disrupt the active, the reactions happen underwater, spacecraft or even pull it down. With the making it difficult for workers to coat the L-R: Yuji Sano, Japan Science and Technology Agency; Earl Maize, NASA Jet Propulsion Laboratory; Günther Tränkle, Ferdinand Braun Institute. Photos: Stacey Crockett aid of new atmospheric models, Cassini material. However, by reducing the en- managed to carefully graze the atmo- ergy and duration of laser pulses, Sano that the pressure is high enough to gener- diode lasers into a single beam. In a more sphere and take a sample. and his colleagues developed a method of ate the necessary shockwaves. By using a sophisticated technique, called coherent During the final descent, mission op- laser peening without any special coating. femtosecond laser, the researchers found beam combination, a laser is split into erators turned Cassini into a real-time This technique has been used for nuclear they could achieve high plasma pressure multiple beams that are then amplified. probe, capable of collecting and sending reactors in Japan since 1999, and is now even without water. As this kind of research continues to data simultaneously – even until its last used in some reactors in the US. Laser technology in general has been advance, Tränkle said, diode lasers will moments. More recently, in 2018, Sano and his developing so fast, many advances in laser become a part of ever improving tech- Cassini was a wild success with count- colleagues designed a handheld laser peening and other applications will likely nology, with applications in everything less discoveries: geysers erupting from system. The typical lasers used for la- be realized over the next several years, from medicine to the lidar systems used Saturn’s moon, Enceladus – which seems ser peening are about a meter wide and Sano said. “We can realize new technolo- for autonomous vehicles. to have the necessary ingredients for life; weigh several tens of kilograms; but the gies we couldn’t imagine at present.” MARCUS WOO

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BiOS Hot Topics: changing of the guard The photonics community this year marked the retirement The evening included the presentation of the 2019 of long-time BiOS co-chairs Rox Anderson and James Biophotonics Technology Innovator Award to Stephen Fujimoto from those roles. Boppart of the University of Illinois at Urbana-Cham- The near-capacity crowd at their ultimate session this paign. The award honors Boppart’s achievement in week broke into applause as Anderson opened with “This computational OCT and its applications to basic and is the largest meeting in the world for biomedical optics, clinical sciences. and that’s because of you!” He added that the reason BiOS The SPIE-Franz Hillenkamp Postdoctoral Fellowship has grown so popular is the diversity of the intellect and in Problem-Driven Biophotonics and Biomedical Optics specialties that are featured in the symposium, such was awarded to Jie Hui of the Boston University Pho- as those involved in medicine, bioscience, and physics. tonics Center and Dr. Andreas Wartak of the Wellman James Fujimoto introduced the new BiOS co-chairs, Center for Photomedicine at Massachusetts General Hos- Jennifer Barton of the University of Arizona and Wolf- pital. Hui’s research is focused on a light-based approach gang Drexler of the University of Vienna. Touching on to treat MRSA-caused diseases in the clinic. Wartak’s the impressive backgrounds of each, Fujimoto noted, research will target an earlier, cheaper, and less invasive “we know the conference diagnosis of eosinophilic will be in good hands.” esophagitis (EoE), a poor- “Rox and I would like ly understood allergic in- to take this opportunity to flammatory condition of thank SPIE, program track the esophagus. chairs, conference chairs, The final award presen- and all of you in the com- tation of the evening was munity for the opportunity the 2019 Britton Chance and the privilege to serve as Biomedical Optics Award co-chairs of BiOS all these to Samuel Achilefu of the years,” said Fujimoto. Washington University “We’d all like to honor School of Medicine in St. and thank Dr. James Fu- Louis. Presented each year jimoto and Dr. Rox An- L-R: Rox Anderson, James Fujimoto, Kent Rochford. Photo: for outstanding lifetime Stacey Crockett derson who have tirelessly contributions through de- served this community since 2004,” said new SPIE CEO velopment of innovative technologies that have facilitated Kent Rochford as he presented the pair with awards advancements in biology or medicine, the award honors for their service. “Their combined leadership has con- Achilefu’s work in optical and molecular imaging that tributed significantly to the growth and importance of enables cancer care and treatment. biomedical optics in the world and the BiOS symposium. Each has brought significant advances to how biomedical Cancer vision optics improve our healthcare.” Following his award presentation, Achilefu gave the eve- Rochford pointed out Fujimoto’s achievements as ning’s first technical presentation, “The Power of Light co-developer of optical coherence tomography (OCT), “a to See and Treat Cancer,” where he described his “Can- ubiquitous technology with many applications.” He noted cer Vision Goggles” – a headset that allows surgeons to that Fujimoto’s prolific career includes 15 patents, nine visualize cancer in the operating room. books, and more than 450 journal articles; and that he “We have developed a simple fluorescent molecule has received numerous awards for the development of for imaging solid tumors and a wearable head-mounted OCT, including the 2017 Russ Prize from the National device to visualize cancer in the operating room,” said Academy of Engineering – considered the Nobel Prize Achilefu. “These combined products synergistically im- of engineering. prove treatment outcomes. Now that we can visualize cancer in real time, we are using light from within the Humanitarian efforts cancer cells to treat them.” “An active researcher, Rox Anderson conceived and de- In conclusion, Achilefu acknowledged the many veloped treatments for birthmarks, lesions, and tattoo people who worked on the project: “surgeons, clini- removal among other innovations,” said Rochford, add- cians, students, engineers, physicists, chemists, biol- ing that Anderson, “brings the wonderful perspective of ogists – basically it takes a village to do what we are having degrees in science as well as in medicine.” He describing today.” noted Anderson’s more than 60 national and interna- Achilefu also acknowledged his friend and mentor tional patents, and the fact that he has co-authored over Britton Chance. “Through his inspiration and the les- 250 scientific books and papers. “We also applaud Dr. sons learned from his hard work ethic, we’ve been able Anderson for his humanitarian efforts to help children to push our technologies, not only to do the pre-clinical in the world who are scarred or disfigured in need of this model, but also work with actual patients, and today help,” Rochford added. we’re taking our technologies around the world to im- Anita Mahadevan-Jansen of Vanderbilt University prove healthcare,” he said. paid tribute to the late Warren S. Grundfest, professor of Long-time facilitator, Sergio Fantini of Tufts Univer- bioengineering and electrical and computer engineering sity,c opened the quick-fire Hot Topics presentations, at UCLA. “Grundfest was one of the founding fathers of which covered several new developments in biomedical BiOS, serving as symposium chair from 1998 to 2003,” optics, specifically diffuse optical imaging, spectroscopy, said Mahadevan-Jansen. He was a pioneer in the trans- fluorescence spectroscopy, optoacoustic tomography, lation of biomedical and biophotonics technology for multiphoton endoscopy, and OCT. improving patient care.” continued on page 34

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THURSDAY, FEBRUARY 7, 2019 | 09 Fiber Optic Components and Fiber Coupled Laser Sources polarization-maintaining for wavelengths 360 – 1800 nm Photonics21 digs in for next phase of continental R&D

Option: Building on some notable recent success stories, the European photonics Amagnetic (Titanium) Optional: Fiber Connectors and platform is anticipating a busy 2019 for innovation. with End Caps Fiber Optic Components

With more than 2500 members, the Photonics21 “technol- everyday life, revolutionizing society with so many differ- ogy platform” represents much of Europe’s photonics com- ent new and innovative applications far beyond obvious Polarization Analyzer munity, embracing industry and research organizations lighting products,” commented Anania and Schulte. “In Series SK010PA Multiple Wavelength Ranges 370 – 1660nm alike. Working closely with the European Commission the past few years alone, [photonics has] created exciting, (EC), its members develop and implement a common pho- game-changing products in terms of diagnostic tools for tonics strategy within the framework of a public-private our health practitioners, improving our environment, partnership (PPP) supported by Horizon 2020 funding and become a keystone component of Industry 4.0.” that is intended to use and develop photonics technology Looking to the future innovation program, they have special routines for PM- fiber evaluation and to spur innovation, growth and jobs in Europe. some lofty aspirations. “If we can maintain a strong polarization alignment determination of the state The past year saw a of polarization (SOP) with all significant change with- four Stokes parameters in the organization. Aldo Kamper arrived as Pho- SAN FRANCISCO, CALIFORNIA tonics21’s new president in 5 - 7 FEBRUARY 2019 January 2017, but around Visit us in North Hall, Booth 5080 18 months later the Osram Opto Semiconductors CEO Lasers for Machine Vision was recruited to head up Wavelengths 405 – 2050 nm the German cabling group Leoni, and departed his Photonics21 role. As a result, the group is currently under the joint care of its two vice presi- dents, Giorgio Anania and Bernd Schulte. They told Show Daily about their hopes and plans for the organization and the wider Line Scan Cameras Monochrome or color from 512 to 8160 pixels. industry through the com- The knitted fabric made by Texinov delivers laser light for photodynamic therapy to every part of a patient’s skin requiring treatment. Photo: Texinov Medical Systems. ing year, and highlighted • USB 3.0 Super Speed • Ruggedized connector some new initiatives as the Horizon 2020 funding period funding commitment, and strengthen the photonics PPP • No external power supply draws to a close. in Horizon Europe, then the instant diagnosis of major “Photonics21 remains in a strong position to foster diseases, the eradication of all road accidents, and the monochrome CAMERA European innovation and is committed to harnessing the creation of at least one million new jobs are some of the power of light to solve our greatest global challenges,” benefits that we expect will be generated by the photonics color Schulte and Anania stated. sector by 2030.” From early 2019 onwards, we can expect to see further announcements of PPP-funded projects, as well as the Microscope tackles sepsis return of the “#Next_photonics Prototype Your Idea” One primary example of that ongoing innovation is a contest. This is a dedicated innovation challenge to push proprietary interferometric, lens-free microscope that SMART CONTROL BOX for more entrepreneurship in photonics, targeting PhD is said to provide the fastest ever detection of sepsis. A The intelligent camera add-on or Masters students, as well as creators with an idea life-threatening condition, sepsis is an inflammatory im- • High-performing signal and image processing for a photonics-based product that can transform into mune response to infections caused by bacteria including • Compact form factor a real business. The competition, said to have proved E. coli and Staphylococcus, which can lead to conditions • Common industry interfaces very popular in 2018, offers a cash prize of €5000 and such as meningitis. On the rise with the emergence of an- • Client user interface for Windows 7/8/10 the opportunity to team up with the Brussels-based in- tibiotic-resistant pathogens, sepsis now kills over 20,000 novation incubator ACTPHAST EU. people every day worldwide – more than prostate cancer, Another important diary date coming up fast is Pho- breast cancer, and HIV/AIDS combined. tonics21’s annual meeting, taking place in Brussels at Approximately the size of a small book, the new mi- the end of March. This year’s host keynote speaker will croscope developed under the Photonics21 project en- be Carl Buhr, deputy head of cabinet within the “Digital titled “Scalable point-of-care and label free microarray Economy and Society” commission led by Mariya Ga- platform for rapid detection of sepsis”, or RAIS for short, briel. During the associated workgroup sessions, prior- has the potential to simultaneously detect more than ity topics for the first photonics-related calls under the one million biomarkers – the tell-tale signs of sepsis forthcoming “Horizon Europe” research and innovation and many other diseases. Whereas current techniques [email protected] www.SuKHamburg.com program – the follow-up to Horizon 2020 – will be of- can take as long as one day to perform a similar test, Schäfter+Kirchhoff develop and manu- ficially launched. the new method combines photonics, microfluidics, and facture laser sources, line scan camera “Photonics technologies have now become a part of continued on page 11 systems and fiber optic products for worldwide distribution and use.

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Photonics21 continued from page 09 what its developers describe as “the world‘s performed in a hospital under general an- ute session, thanks to a new wearable molecular biology techniques to produce first while-you-wait test for skin cancer”. esthesia to discover if it is spreading. This photonics technology. Under another a result in just 30 minutes. The imaging system, intended to can take weeks to perform, is very expen- Photonics21 project, scientists at Texi- Coordinated by ICFO, the Institute of eliminate discomfort and uncertainty sive and can be debilitating for a patient. nov Medical Textiles, based in La Tour Photonic Sciences in Barcelona, Spain, for patients, is able to fit every stage of “About 80% of the time, the biopsy pro- du Pin, France, led the development of RAIS is seen as a major success story disease identification within the short duces a negative result, with no sign of the “Fluxmedicare” – a knitted fabric that for the photonics PPP. Josselin Pello, a time of a single doctor’s appointment. cancer spreading. There has to be a better helps treat inflamed skin or lesions with senior researcher on the project at ICFO, Using a handheld scanner, they can peer way: our scanner may radically improve photodynamic therapy (PDT). explains: “Doctors need a quick, reliable beneath a patient’s skin to examine the the abilities of dermatologists to decide Described by some users as a “mira- way of detecting sepsis, and the stage microscopic landscape of a suspect lesion, on the nature of a melanoma, [although] cle cure” in clinical trials, the pain-free it has reached. Current methods approach is touted as offering the are too slow. They can only look at fastest way to eradicate the identi- a couple of parameters at a time, fied skin conditions, with no side and they will not tell the physician effects. The knitted fabric acts like what type of bacteria is present a waveguide to deliver therapeutic that is causing sepsis. A doctor laser light to the entire region of may not therefore prescribe the skin requiring treatment. correct treatment in time.” Nadege Boucard, general man- Pello points out that the RAIS ager of research and development microscope can simultaneously at Texinov, said: “Fluxmedicare detect many biomarkers, includ- is unprecedented in the field of ing micro-ribonucleic acids and treating skin conditions. Since interleukins. “[It] will let you know the lighting textile wraps around the bacteria source much earlier, the contours of a patient, the light allowing you to choose the correct emitted by our device is the same treatment sooner,” he says. The level at every part of the body un- RAIS project received a grant of der treatment, meaning the beams €3 million via the photonics PPP are homogeneous.” under the Horizon 2020 program, Under a photonics PPP project, the RAIS development team at ICFO has led development of a microscope Photonics21 said of the project: offering a much faster way to diagnose sepsis. Photo: ICFO. with the team estimating that a “This development is yet another commercial device based on its beta pro- in a process that takes just 20 seconds. further clinical trials will be needed to success for photonics technology. It has totype could potentially provide results at Based on optical coherence tomogra- conclusively prove the technology.” now been successfully tested in clinical a cost as low as €50 per patient. phy (OCT), a technique more commonly The ADVANCE project received a grant trials and is ready to go, meaning more used in retinal screening, the scanner cre- of €2.3 million under the Horizon 2020 sufferers of such skin conditions will find Laser pen for ‘while ates a 3D color image of microstructures funding period, and featured partners from new hope, quicker, easier, and in a pain- you wait’ cancer test and blood vessels under the skin – pro- Germany, Denmark, Italy, and Serbia. less appointment.” The Photonics21 team says that another viding a diagnosis without the need for Fluxmedicare was developed under successful PPP-related development has any invasive procedures. Fabric treats skin diseases the “PHOS-ISTOS” consortium, which been delivered by the Automatic Detection Project leader Jon Holmes, from the Other, less dangerous but debilitating secured EC grant support of €2.4 mil- of VAscular Networks for Cancer Evalua- UK company Michelson Diagnostics, ex- skin conditions such as actinic keratosis lion. The team comprised participants tion (ADVANCE) project team. They have plains: “Every melanoma above a certain (scaly spots on sun-damaged skin, often from across Europe, including the diode produced a portable laser scanner that can thickness could have spread to other parts pre-cancerous), psoriasis (autoimmune laser manufacturer and Photonics West diagnose a malignant melanoma in less of the body. At present, all patients with disease causing abnormal skin) and acne exhibitor Modulight. than one minute, promising to become such melanomas have to wait for a biopsy can now be treated in a single 150 min- MATTHEW PEACH

Acousto-optics | Electro-optics | Fiber optics | Precision optics | Systems Challenge us to show how our expertise can work for you © Courtesy of ESA

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THURSDAY, FEBRUARY 7, 2019 | 13

Specific treatment Fellowship winners tackle twin strategies “These findings are fascinating both to our research team and to the physicians we healthcare challenges have met,” Hui commented. “Clinical ap- Researchers supported by SPIE-Franz Hillenkamp Postdoctoral Fellowships are plications of our technology to benefit pa- tients would be even more exciting. Right developing photonics technologies to treat MRSA infections and diagnose esophageal now, we are working towards the clinical disease. Both projects could have significant impact in clinics. translation of this technology to treat spe- cific diseases, for example skin and uri- The challenge to healthcare posed by search team discovered that staphyloxan- source both reduces the potential photo- nary tract infections caused by MRSA. As MRSA is an enormous global concern, thin, an endogenous pigment produced by thermal effect when compared with con- it moves towards the clinic, we will cer- given the resistance to several widely used the bacteria and bound in its membrane, tinuous-wave light sources, and improves tainly face some technical challenges. One antibiotics that these bacterial infections is the specific molecular target for the blue photolysis efficiency and depth, subse- example is the light delivery system, where can possess. illumination.” quently killing MRSA A traditional first line of defense in Staphyloxanthin has an antioxidant ac- much more effective- hospitals and clinics has been stringent tion, a key element in the microbe’s defense ly,” said Hui. “We also controls on cleanliness, to limit the spread against the reactive oxidation process em- revealed the detailed of infection. But an optical technique un- ployed by some conventional antibacterial killing mechanism for der development at Boston University’s treatments. Weaken or damage the staphy- MRSA, which opens Photonics Center aims to eliminate the loxanthin, and you can deal a serious blow many opportunities for potentially deadly pathogens with a more to MRSA’s formidable toughness. clinical applications of targeted approach. In 2017, Hui’s project found that our technology. These Jie Hui, a member of Ji-Xin Cheng’s staphyloxanthin is prone to photobleach- findings are novel and group at Boston, is working on the use ing by blue light, which ruptures cell have high potential of blue laser light to disrupt the antibiot- membranes and kills the bacteria cells. for development into a ic-resistant bacteria, potentially allowing This effect was proved to work on MRSA therapeutic platform in the clinic.” “Staphyloxanthin, an endogenous pigment This project builds upon work that won Jie Hui (left), a researcher at the Boston University Photonics produced by the bacteria, is the specific the group a Transla- Center, is working on a blue laser treatment for MRSA. He is tional Research Award hopeful that the approach could find use in early-adopter molecular target for the blue illumination.” hospitals within two years. Photo: Boston University. at last year’s Photonics JIE HUI, BOSTON UNIVERSITY PHOTONICS CENTER. West, and Jie Hui is now a recipient of we may need to develop specific strategies a 2019 SPIE-Franz Hillenkamp Post- to match each application.” a treatment to be developed specifically cultures, MRSA-infected macrophage doctoral Fellowship in Problem-Driven This may in turn involve different pa- for MRSA-caused diseases. cells, bacterial biofilms, and a wound in- Biophotonics and Biomedical Optics. rameters for laser treatment in terms of “It has been well documented for fection model in mice. More recently, the This annual award, recognized during dosage, illumination area, and treatment more than a decade that blue light has project set out to address a long-standing Saturday’s BiOS Hot Topics session, is time, alongside the possible adoption of an antimicrobial effect, but its underlying question within the field: what is the best one of a pair of fellowships targeted at specific optical fibers for endoscopic and mechanism has been a mystery and the blue light source for killing MRSA? interdisciplinary problem-driven re- intravascular applications. The nature of treatment efficiency is limited, which has “My recent work, grounded in the search and opportunities for translating each individual infected site and the gen- blocked the translation of this approach physics of staphyloxanthin photolysis, new technologies into clinical practice for eral condition of a patient are also likely into clinics,” commented Hui. “Our re- demonstrated that a pulsed blue laser improving human health. continued on page 15

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Fellowship winners continued from page 13 lowed by histopathology analysis of the instance, movement mainly caused by From his perspective at the Wellman to play a role. Ultimately, each specific sample to examine the influx of a certain peristalsis (muscle contractions in the Center, Wartak recognizes that transla- disease may well require its own partic- type of white blood cell that character- digestive tract), which cannot be fully tion can be helped or hindered by a num- ular treatment strategy. izes the condition. But this is by nature corrected by computational methods. Im- ber of factors, and that optimizing the Successful translation of any new bio- invasive, expensive, requires sedation, age resolutions able to reveal the smallest performance of a new imaging modality photonics technology, whether for diagno- and is prone to high sampling variabil- details of the biological processes under is not the end of the story. Translation sis or therapy, needs to be grounded on ity. The Wellman also depends on successful collaboration solid scientific studies as well as strong Center project, between several different scientific de- collaboration among scientists, engineers, based in the lab of partments, medical clinics, and indus- and physicians. For medical devices in Guillermo Tear- try, as well as the funding and regulatory particular, it also requires significant in- ney, is developing agencies concerned. vestments to be put in place in order to a more attrac- Project teams incorporating all rele- bring them to market. tive optics-based vant stakeholders have the best chance “We are very positive on the clini- alternative. of eventually entering the clinical market cal translation of this particular tech- “We will apply a with their product, making it essential to nique,” Hui said. “Antibiotic resistance technique that has have an interdisciplinary field of experts is currently a serious public health issue, been recently de- on board from the start of the effort. and MRSA has been listed by the World veloped in our lab, Health Organization among its ‘priority’ termed tethered pathogens — the 12 families of bacteria capsule endomi- that pose the greatest threat to human croscopy (TCE), health. This means our technique occu- in which a pill de- pies a very valuable niche from the clini- scends down the Andreas Wartak’s optical coherence tomography “pill”, for cal point of view, as well as being simple, esophagus when diagnosing allergy-related inflammation of the esophagus. Photo: Andreas Wartak. safe, and effective.” swallowed and is The group is currently initiating a then withdrawn back up by means of a way in EoE are also essential, delivered proof-of-concept clinical study using tether,” explained Wartak. “This capsule in this case by exploiting recent advances the blue-light technology, likely to take will incorporate a sophisticated new form in light sources and camera technology. MRSA bacteria, as seen under the electron microscope. Image: The Wellcome Trust. place this year. After that, Hui is hopeful of optical coherence tomography (OCT), “The key challenge of this project is to of a smooth path through larger clinical for visualizing the inside of the esophagus merge specialized high-end equipment “Bench-to-bedside translation can trials and regulatory approval, with ear- at the cellular level.” and customized components developed be a long and winding road, and there ly-adopter hospitals perhaps able to deploy OCT’s ability to record depth scans of in-house, to build a high-speed and are definitely hurdles in the way of every the technology within the next two years. living samples from backscattered light is high-resolution instrument,” Wartak said. technology striving towards the clinical “We really appreciate that the SPIE well established, in particular for ophthal- “Since we only started recently, most of market,” he said. “I believe there is now community recognizes our research work mic imaging. But it is also well on its way the work still lies ahead, but I feel that we a clear trend of more biophotonic modal- in this direction, by award- have all the necessary build- ities, whether diagnostic or therapeutic, ing both the prestigious “I believe there is now a clear ing blocks available to make successfully making it into the clinic, and SPIE-Franz Hillenkamp this project a success. Our the drive towards translation now seems Postdoctoral Fellowship this trend of more biophotonic lab has the required techno- more pronounced. Nevertheless, there year and SPIE Translational modalities, whether diagnostic logical expertise and sophis- is always room for improvement and, in Research Award in 2018,” he tication, and has gathered particular, the need for suitable funding.” commented. “Both awards or therapeutic, successfully tremendous experience in As a researcher from Europe now are highly selective, and tar- advancing endoscopic OCT working in the US, Wartak has also ob- get the most promising bio- making it into the clinic.” over the last two decades, served some geographical differences in photonics technologies with while MGH offers an excep- the translational funding structures, with ANDREAS WARTAK, high translational potential. tional clinical environment. the more extensive private funding oppor- These awards have already WELLMAN CENTER FOR PHOTOMEDICINE. I am positive that we will tunities available in the US potentially drawn more attention to our reach our goals.” facilitating higher-risk proposals than the research findings, and will further accel- to becoming a major technology for intra- Wartak currently expects an initial more conservative public agencies might erate the translation of our technologies luminal diagnosis, especially in the car- animal study to be followed by a pilot opt to support. into the clinic and into the market. In the diovascular and gastrointestinal systems. clinical trial in humans, to demonstrate Wartak’s receipt of the SPIE-Franz long run, I think these awards will prove “Our project tries to further extend the safety and feasibility in both healthy Hillenkamp Postdoctoral Fellowship will to have benefited both the SPIE research portfolio of gastrointestinal diseases that subjects and EoE patients, adjusting the also now play a part, by allowing him to community, and patients in the clinic.” already profit from OCT’s tomographic instrument design by iteration during the focus entirely on the EoE research proj- imaging approach,” commented Wartak. process. After that, larger-scale clinical ect, increasing the chances of a successful Diagnosing esophageal “We will investigate epithelial tissue in- studies are planned at MGH before po- outcome. disease with OCT ‘pill’ flammation, as well as structural chang- tential multi-center studies. “I personally feel motivated by the fact At the Wellman Center for Photomedi- es and sub-epithelial remodeling in EoE. that my research not only seems mean- cine, located at Massachusetts General This complementary information will Diverse teams ingful to myself, but also to SPIE and thus Hospital (MGH), Andreas Wartak’s re- provide key insights into disease devel- ease translation to a wider general public,” he said. “Con- search into optical diagnosis of eosino- opment and progression over time, that Eventual translation of the technology gresses, meetings, and conferences such philic esophagitis (EoE) is paving the way should ultimately lead to an advance in from the laboratory to the clinic is another as Photonics West are essential. Research for earlier and less invasive treatment of research, diagnosis and therapy for EoE.” major consideration. The hurdles involved is all about sharing discoveries, inven- this allergic inflammatory condition of As with most in vivo imaging modal- in bringing a novel biophotonics tech- tions and results, but it is at conferences the esophagus, a disease whose exact na- ities, the obstacles facing the Wellman nique to its chosen clinical markets are a that scientists like us have the chance to ture is still not fully understood. Center project include the need for suffi- natural topic of discussion at Photonics experience research in a more personal Diagnosis of EoE normally involves a ciently fast imaging speeds to counteract West, which is once again addressing the and probably more relatable way.” biopsy performed with an endoscope, fol- the unavoidable sample motion. In this issue as part of the BiOS symposium. TIM HAYES

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pco-tech.com optics.org product focus SPIE Photonics West 2019 Edition

Photonics West is the premier photonics and laser event. With more than 1,250 companies, this exhibition continues to be the flagship event to find the latest products, tools, 23 and applications for your research or business needs.

The Moscone Center, Moscone North and South San Francisco, California, United States product focus 5th - 7th February 2019

Welcome to the optics.org Product Focus which we have published specifically for All this information and more can be found on the optics.org website. Photonics West 2019 in partnership with SPIE and the Photonics West Show Daily. Simply go to www.optics.org for all the latest product and application news. Here you will find an effective at-a-glance guide to some of the latest products available Alternatively, why not sign up to our free weekly newsletter on the market with booth numbers if available making it easy for you to check out the (www.optics.org/newsletter) and get the information delivered direct. products for yourself.

Bristol Instruments, Inc. Visit us at Booth #235 Nanoscribe GmbH Visit us at Booth #366

Wavelength Meters – Fast and Photonic Professional GT2: Accurate for CW and Pulsed Lasers Printer for 3D Microfabrication Bristol Instruments’ wavelength meters are used by Nanoscribe´s Photonic Professional GT2 is the world’s scientists and engineers who need to know the exact highest-resolution 3D printer. It shifts the boundaries wavelength of their lasers. of ultra-precise additive manufacturing for the fabrication of macroscale structures with millimeter Systems are available for CW and pulsed lasers that dimensions. operate at wavelengths from 375 nm to 12 µm. The two-photon polymerization driven systems These systems use proven interferometer-based combine the technology of two-photon technology to measure absolute wavelength to an Contact Details polymerization with a regular 3D printing workflow for Contact Details accuracy as high as ± 0.0001 nm and offer the fastest Bristol Instruments, Inc. additive manufacturing and maskless lithography. sustained measurement rate of 1 kHz. Nanoscribe GmbH 770 Canning Parkway New features, new tools, and new processes extend Hermann-von-Helmholtz-Platz 1 Continuous calibration with a built-in wavelength Victor, New York 14564 the microfabrication capabilities of Nanoscribe´s 3D D-76344 Eggenstein-Leopoldshafen standard guarantees the reliable accuracy required for www.bristol-inst.com printers and make them a valuable tool for scientific Germany the most meaningful experimental results. [email protected] and industrial applications like photonics, micro-optics, www.nanoscribe.de Tel: +1 (585) 924-2620 micro-fluidics, MEMS, or biomedical engineering. [email protected] Fax: +1 (585) 924-2623 https://www.nanoscribe.de/en/products/photonic- Tel: +49 721 60 82 88 40 professional-gt2/?pk_campaign=opticsorg

First Light Imaging Visit us at Booth #1059J, French Pavilion Oz Optics Ltd Visit us at Booth #4548

C-RED cameras, above and beyond: OCT components High Dynamic Range OZ Optics is introducing a new line of Fiber Optic Exclusively for Photonics West, C-RED 2 600 + HDR is a Components for OCT Applications: high dynamic range 640x512 VGA TEC2 InGaAs SWIR High Speed Polarization Controller/Scrambler, 330ps camera : ultra fast (600 FPS FF), very low noise (<30 Electrically/Manual Controlled Optical Delay Line, electrons), very low dark (300 e/p/s), and High Dynamic Collimators/Focusers, Electrical Controlled Variable (93dB linear dynamic range and true 16 bits image), all at Attenuators, Faraday Rotators/Mirrors, Isolators, Fiber the same time. Pigtailed Ultra Stable Laser Module, Fused Coupler, Designed for Scientific, Industrial or Surveillance Polarizers, Reflectors, Directional Fiber Optic Power Contact Details Contact Details applications where sensitivity, speed, dynamic and Monitors (Taps/Photodiodes), Miniature Inline resolution are crucial, easy as plug-and-play, C-RED First Light Imaging OZ Optics Ltd Polarization Maintaining Splitters/Taps/Combiners, Cameras are able to empower any system. Europarc Sainte Victoire, Bat 6 219 Westbrook Road, Ottawa, Route de Valbrillant, Le Canet Polarization Maintaining Fused Fiber Couplers/Splitters, Ontario, K0A 1L0 More information: www.first-light-imaging.com/ 13590 Meyreuil, FRANCE Optical Circulator, Voltage Controlled Tunable Filter, www.ozoptics.com products/ www.first-light-imaging.com Inline Fabry-Perot Tunable Filters. [email protected] [email protected] Tel: +1 613-831-0981 Tel : +33 (0) 4 42 61 29 20 Fax: +1 613-836-5089

Iridian Spectral Technologies Visit us at Booth #644 Voltage Multipliers Inc. Visit us at Booth #4589

Iridian optical filters – providing “More Signal, 10kV and 15kV High Voltage Less Background” for LiDAR applications Optodiodes LIDAR systems work with common laser wavelengths including 532nm and OZ100 and OZ150 families feature high voltage 1064nm with the wavelengths typically used in automotive applications being isolation in a small package. 905nm and 1550nm. Regardless of the wavelength employed, Iridian provides customized optical filter solutions for LIDAR applications providing “More Signal, Reverse current, in μA, is generated when with Less Background” from design and manufacture of initial prototypes through the diode junctions are exposed to light. The to high volume production in our ISO9001:2015 certified Canadian operation. response is linear, meaning the current level can • High transmission at the laser wavelength (>90%) be used to control and monitor isolated systems. Narrow bandwidths (<1nm to 20+nm dependent on the system The optically clear over-encapsulation preserves Contact Details Contact Details • requirements) light sensitivity, protects the device, and provides Iridian Spectral Technologies Voltage Multipliers, Inc. Deep blocking (OD3-5 or better over detector range) mechanical stability. • 2700 Swansea Crescent, Ottawa, 8711 W. Roosevelt Ave., • No maintenance/calibration needed; highly stable; environmentally robust ON, Canada K1G6R8 Applications include noisy industrial Visalia, CA, USA 93291 and reliable www.iridian.ca environments and sensitive instrumentation www.voltagemultipliers.com/Aliases/ Low sensitivity to angles of incidence (AOI) and temperature variation [email protected] where high isolation is needed, or in controlled LPs/OZ150_and_OZ100.html • feedback systems like high voltage opto-couplers Low cost, high volume manufacturing capabilities Tel: +1 (613) 741 4513 [email protected] • or voltage regulators. Link: https://www.iridian.ca/application-areas/optical-filters-lidar-applications/ Twitter: @IridianSpectral

optics.org: Contact Rob Fisher, Advertising Sales tel: +44 (0)117 905 5330 fax: +44 (0)117 905 5331 email: [email protected] follow us on twitter @opticsorg optics.org product focus SPIE Photonics West 2019 Edition

EKSMA OPTICS Visit us at Booth #1633 Navitar Visit us at Booth #245

Ultra High LIDT Laser Mirrors 4K HDR Lens/Camera Modules, at 1064 nm Large Format Imaging Systems EKSMA Optics offers ultra high damage threshold Navitar imaging technologies being showcased this laser mirrors for 1064 nm laser wavelength with year include: 4K HDR lens modules for UAV and AV reflection value R>99.9%. forward-facing camera systems, large format zoom Laser induced damage threshold of >40 J/cm2 and fixed Resolv4K imaging lens systems, Pixelink was measured for both s and p polarization pulses polarization cameras for broader visual detection at 1064 nm, 10 ns, 20 Hz, AOI=45° under ISO of material properties, and precision microscope standard 21254-2 1000-on-1 conditions. objectives. Contact Details Contact Details New ultra-high damage laser mirrors are produced We design, build, test and assemble optical solutions EKSMA OPTICS using advanced IBS coating technology. of the highest quality that are used in new emerging Navitar, Inc. Optolita UAB, Mokslininkų str. 11 markets. www.navitar.com Ultra high LIDT mirrors for other laser wavelengths LT-08412 Vilnius are available upon request. Lithuania Stop by booth #245 - Ask us about our lens-sensor www.eksmaoptics.com active alignment capabilities and talk with us about your next imaging technology application. [email protected] Tel: +370 5 272 99 00

Pixelink a Navitar Company Visit us at Booth #245 Ophir Visit us at Booth #927

New HDR and Polarization Camera Beam Profiling Camera with GigE Models with Sony IMX Pregius Interface for High-Speed Industrial CMOS Sensors Applications Pixelink has expanded their USB3 Vision industrial The Ophir® SP920G GigE Silicon CCD High Resolution Camera camera line with new HDR and polarization models. is designed for industrial laser beam profiling applications. Accurately captures and analyzes wavelengths from 190nm - The PL-D757 and PL-D753, featuring Sony 3rd 1100nm. generation IMX420 and IMX421 sensors, capture Features a compact design, wide dynamic range, unparalleled and combine dual ADC images into a single hybrid signal to noise ratio, and high-speed GigE (Gigabit Ethernet) HDR image directly on camera – making them ideal Contact Details interface. Contact Details for HDR imaging applications such as moving parts Delivers 1624 x 1224 pixel resolution with a 4.4µm pixel pitch for Ophir inspection. Pixelink www.pixelink.com measuring beam widths of 44μm - 5.3mm. 3050 North 300 West The PL-D755-POL polarization machine vision camera, Ideal for measuring CW and pulsed laser profiles in laser cutting of North Logan, UT 84341 USA featuring Sony’s IMX250MZR image sensor with pixel- medical devices or welding of dissimilar materials. www.ophiropt.com level quad polarization filter technology, offers broader Link: https://www.ophiropt.com/laser--measurement/beam- [email protected] visual detection and characterization capabilities of profilers/products/Beam-Profiling/Camera-Based-Beam-Profiling- Tel: +1 435 753 3729 material properties over conventional monochrome with-BeamGage/SP920G-Beam-Profiling-Camera sensors.

Synopsys Visit us at Booth #1259 Radiant Vision Systems, LLC Visit us at Booth #3113

Meet Optical Design Goals Faster NIR Intensity Lens measures near-infrared and Better with CODE V light sources used for 3D sensing Synopsys’ CODE V® has been leading optical design The Near-Infrared (NIR) Intensity Lens system from Radiant software innovation for over 40 years. combines a Fourier-optic lens with 16-megapixel CCD imaging radiometer for precise characterization of NIR- Extended formulations help optical designers emitting light sources used for facial recognition and other 3D meet stringent packaging and image resolution sensing applications. requirements for compact camera systems. The system captures angular data to ±70 degrees in a single Sophisticated algorithms and built-in expert tools image to efficiently measure radiant intensity across the enable the design of cutting-edge AR/VR systems. Contact Details distribution, and analyzes structured light patterns produced Contact Details Synopsys, Inc. by diffractive optical elements (DOE). Radiant Vision Systems, LLC Visit Synopsys in Booth 1259 at SPIE Photonics West Optical Solutions Group Measure near-IR LEDs and lasers 18640 NE 67th Court 2019 to get a demo or contact us today for a free www.synopsys.com/optical-solutions/ • Redmond, WA 98052 USA evaluation. codev/optical-design.html • Capture light across ±70 degrees www.RadiantVisionSystems.com [email protected] • Output extensive DOE statistics [email protected] Tel: +1 626-795-9101 • Qualify facial and gesture recognition technology Tel: +1 (425) 844-0152

ADIT Electron Tubes Visit us at Booth #1853 ALPhANOV Visit us at Booth #1059 F, French Pavilion

ADIT Electron Tubes introduces a MIR-PULS – ALPhANOV unveils a complete range of Photodetector new femtosecond laser tunable Modules: over 1800-2100nm. Photodetector modules are available in cylindrical and Part of the PULS family product, MIR-PULS delivers rectangular format for photon counting and analog signal 20mW of sub-300fs TFL pulses at 40Mhz, over the detection using 25mm and 30mm diameter photomultiplier spectral range of 1800-2100nm. tubes. It offers a unique solution for applications such as • Spectral range 170nm to 850nm available bioimaging, optogenetics, spectroscopy or seed Signal output – analog, TTL, USB source for Thulium/Holmium based amplifier Contact Details Contact Details • systems. • Dual TTL and USB available ADIT Electron Tubes, 300 Crane Street ALPhANOV Operates from +5 volts Sweetwater, TX 79556 This new laser oscillator developed by ALPhANOV Institut d’optique d’Aquitaine • illustrates its expertise in modeling, designing and Rue François Mitterrand, Dynamic range up to 100 Mcps www.electrontubes.com • prototyping innovative fiber laser sources. 33400 Talence, France Choice of 3 software configurable counting modes [email protected] • Tel: +1 325-235 1418 Always with the user in mind, ALPhANOV is also www.alphanov.com • HV and data retrieval controlled by dedicated application Toll free: 800-399 4557 ready to customize this laser upon request. [email protected] software Fax: 325-235 2872 Tel: +33 524 545 200 We welcome your inquiry for custom modules. Cell: 862-209 0653

optics.org: Contact Rob Fisher, Advertising Sales tel: +44 (0)117 905 5330 fax: +44 (0)117 905 5331 email: [email protected] follow us on twitter @opticsorg optics.org product focus SPIE Photonics West 2019 Edition

Ophir Visit us at Booth #927 Bristol Instruments, Inc. Visit us at Booth #235

Advanced Laser Power / Energy Meter Spectrum Analyzer— High Features Sophisticated Touch-Screen Resolution and High Accuracy Display The Laser Spectrum Analyzer from Bristol Instruments Ophir® Centauri is a compact, portable laser power / energy operates as both a high-resolution spectrum analyzer meter for precise measurements of laser performance over time. and a high-accuracy wavelength meter. Features a large, sophisticated touch-screen for visual review of These systems are for scientists and engineers who data using a wide range of display formats, such as Digital with need to know the spectral properties of their lasers Bargraph, Pulse Chart, and Real Time Statistics Displays. that operate from 375 nm to 12 µm. Advanced math functions include Density, Scale Factor, and With spectral resolution up to 2 GHz, wavelength Contact Details Normalize Against Baseline. Contact Details accuracy as high as ± 0.0001 nm, and an optical Ophir Bristol Instruments, Inc. Available in single and dual-channel versions. rejection ratio of more than 40 dB, this instrument 3050 North 300 West 770 Canning Parkway Compatible with all standard Ophir thermal, photodiode, and North Logan, UT 84341 USA provides the most complete analysis needed for the Victor, New York 14564 pyroelectric sensors, including the award-winning BeamTrack most demanding applications. power / position / size sensors. www.ophiropt.com www.bristol-inst.com [email protected] https://www.ophiropt.com/laser--measurement/laser-power-energy- [email protected] meters/products/laser-power-meters/centauri-dual-channel Tel: +1 435 753 3729 Tel: +1 (585) 924-2620 Fax: +1 (585) 924-2623

Diamond SA Visit us at Booth #4786 - North Hall Optikos Visit us at Booth #2151

DIAMOND announces innovative Lens Temperature Testing Module fiber optic interconnect solutions for for Automotive Applications demanding applications Following extensive testing and development in our Harsh Environmental surroundings can adversely affect the own IQ Lab, Optikos is pleased to announce the release operation of systems utilizing fiber optics. of a new line of configurable Temperature Testing To combat these conditions, Diamond has developed a Modules to be used with our OpTest® Lens Testing wide range of strong, reliable, and customizable optical Systems. interconnect solutions. Diamond’s unique Multipurpose DM This product line has been developed to meet insert combines unparalleled fiber core concentricity and increasing customer demand - particularly from test Contact Details Contact Details superior optical performance. engineers in the automotive camera market - to evaluate Diamond USA Inc. Optikos Corporation In addition, IP ratings are met through solid and unique the performance of lenses over extended temperature connector construction. 85 Rangeway Road, Bldg. 3 107 Audubon Rd., Bldg. 3 North Billerica, MA 01862 ranges. Wakefield, MA 01880 USA In addition to the optical connectors, electrical contacts can www.diausa.com www.optikos.com also be integrated. Visit us in Booth #4786 in the North Hall to [email protected] [email protected] see the new and innovative DM Insert. Tel: +1 978 256 6544 Tel: +1 617 354 7557

Ibsen Photonics Visit us at Booth #663 Phasics Visit us at Booth #4165

Ibsen offers highly efficient SID4 SWIR: High-resolution wavefront spectrometer platform specifically sensor from 0.9 to 1.7 µm for laser and targeting Optical Coherence optics metrology Tomography Phasics offers metrology and imaging solutions to laser The EAGLE platform comprises high resolution, engineers, lens manufacturers and cell biologists. compact, and robust spectrometers, suited for With a range covering UV to far infrared, our high resolution OEM integration into medical and industrial grade wavefront sensing solutions - based on the patented instruments for applications like Raman and SD-OCT. Quadriwave Lateral Shearing Interferometry technology - combine high accuracy, best-in-class dynamic range and ease The EAGLE OCT-S spectrometer is very compact due to Contact Details of use. Contact Details the use of Ibsen’s wide bandwidth transmission gratings. Ibsen Photonics Visit us to discover how our new range of SWIR sensors fully Phasics These unique gratings furthermore enable us to offer Ryttermarken 17, DK-3520 Farum characterizes laser sources, as well as assemblies and lenses used www.phasicscorp.com higher efficiency than any competing technology. Denmark in free space optical communications, aerospace instruments [email protected] The wavelength range of the standard version is 810 – www.ibsen.com and defense night vision. Tel: +1 415 650 8476 900nm, but can be customized to other ranges. EAGLE [email protected] OCT-S is supplied with Teledyne E2V OctoPlus camera Tel: +45 44 34 70 00 with 2048 tall pixels.

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optics.org: Contact Rob Fisher, Advertising Sales tel: +44 (0)117 905 5330 fax: +44 (0)117 905 5331 email: [email protected] follow us on twitter @opticsorg optics.org product focus SPIE Photonics West 2019 Edition

Diverse Optics Inc. Visit us at Booth #2538 Archer OpTx Inc. Visit us at Booth #333

Custom Polymer Optics An Optical Bench that won’t give Diverse Optics specialize in precision injection molding you the Blues! and single point diamond turning of custom polymer Archer OpTx will soon be offering an optical bench optics. representative of their optical quality at globally Reduce cost, trim weight, improve performance, and competitive pricing. This optical bench will be simplify your product design by implementing precision a turnkey, all-in-one solution to your metrology polymer optics! requirements. There is no need for purchasing We do it all; prototyping to series production of free- expensive upgrades or software. forms ,spheres, micro-optics, aspheres, domes, convex/ The new Archer OpTx optical bench will be concave, plano/convex, bi-convex, diffractives, Fresnels, Contact Details capable of measuring focal lengths of 3mm Contact Details prisms, light-pipes, lens arrays, collimators, combiners, Letty Trevino, Sales Engineer – 2300mm in reflection and transmission. Archer OpTx, Inc. toroids, CPC’s, TIR’s, parabolics, off-axis, ellipticals, and Diverse Optics Inc., 10310 Regis Court, Live measurement standards of EFL, BFL, FFL, 1208 Sigma Court more. Rancho Cucamonga, CA 91730 centration, radius of curvature, and MTF. Rockwall, TX 75087 USA www.archeroptx.com Whether its thousands of molded optics or a few www.diverseoptics.com MTF measurements with precision accuracy. diamond turned prototypes, we’ll show you how [email protected] [email protected] polymer optics are perfected! Tel: +1 (909) 593-9330 Tel: +1-972-722-1064 Fax: +1 (909) 596-1452 Fax: +1-972-722-1063

TOPTICA Photonics AG Visit us at Booth #641 SPI Lasers UK Ltd Visit us at Booth #1068, South Hall

Powerful 920 nm redENERGY Pulsed Fiber Laser Femtosecond Laser sets new levels of versatility! TOPTICA Photonics AG (based in Graefelfing/Munich, Our redENERGY G4 200W EP-Z Pulsed fiber laser Germany) has introduced a new high-power extends the power range of the G4 platform fiber laser system for microscopy applications with greater pulse energy, peak power and (neurosciences, 2-photon excitation). pulse repetition frequency. The 920 nm emitting laser delivers sub-100fs Combining these features with the G4’s range with more than 1 Watt average power at 80 MHz of pulses provide a high level flexibility across repetition rate. Contact Details a number of applications including high speed Contact Details The FemtoFiber ultra 920 represents the only TOPTICA Photonics AG welding, cleaning, cutting and drilling. SPI Lasers UK Ltd 6 Wellington Park, Tollbar Way, Hedge End, fiber laser currently on the market that combines Lochhamer Schlag 19, 82166 Graefelfing (Munich), Germany Southampton SO30 2QU shortest pulses with highest power levels in an www.toptica.com United Kingdom air-cooled design. [email protected] www.spilasers.com [email protected] [email protected] Tel: +49 89 85837-0 Tel: +44 (0)1489 779 696 – Option 1 Fax: +49 89 85837-200

Boston Micromachines Corp. Visit us at Booth #440 Zygo Corporation Visit us at Booth #1342

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optics.org: Contact Rob Fisher, Advertising Sales tel: +44 (0)117 905 5330 fax: +44 (0)117 905 5331 email: [email protected] follow us on twitter @opticsorg THURSDAY, FEBRUARY 7, 2019 | 21

Among the lidar companies high- Optics tech drives CES innovations lighting new advances at CES 2019 was Prism Award winner Blackmore, whose From smart glasses to autonomous vehicles, photonics technology and frequency-modulated multi-beam system the world of consumer electronics seem closer than ever. now boasts a remarkable range of 450 meters, alongside a wide field of view. Photonics innovation has a long associ- life), and contrast. hibitor Luminar Technologies on its Already available for pre-order and with ation with consumer electronics, right The Sunnyvale, California, firm’s new roof, alongside a radar system, numer- initial samples shipping now, Blackmore from the early days of liquid crystal dis- “DigiLens Crystal” platform is based ous cameras, and additional lidar sensors says that full systems will ship to cus- plays, through the emergence of optical around waveguides made under license positioned around its body. Everything tomers from Q2 this year. That high per- data storage in the 1980s, digital cam- by Taiwan-based Young Optics, and is motivated by improving safety and re- formance comes at a cost of “less than eras, Blu-ray discs and the like. But the leverages digital light processor (DLP) ducing the incidence of road collisions $20,000” to strategic partners. link has grown to such an extent in recent technology from Texas years that the topics under discussion at Instruments. Glass com- the annual CES event in Las Vegas and panies offering the kind Photonics West have become increasingly of high-precision wafers intertwined. needed for mass produc- At CES 2019 last month, that trend was tion of suitable waveguides once again in evidence. Photonics-based are also emerging as key technology themes included the latest players in the AR/VR/MR augmented, virtual, and mixed reality ecosystem, with Photonics (AR/VR/MR) headsets and glasses, new West exhibitors Corning micro-LED array displays, and a whole and Schott among those host of new lidar and camera systems de- involved. Vuzix was anoth- signed for today’s driver assistance and er AR smart glasses ven- tomorrow’s fully autonomous cars. dor to present on the topic The clearest link between the two of waveguide technology at events is AR/VR/MR, and with good rea- Photonics West. son. Perhaps the greatest challenge facing In recent years CES has the companies developing these technol- also become a key date in ogies is to improve their size, weight, and the calendar for the au- performance to make them truly immer- tomotive industry, with sive and portable. And that comes right car manufacturers using Augmented, virtual, and mixed reality (AR/VR/MR) technologies were again a huge trend at CES 2019, as well as the subject of a dedicated conference and expo at Photonics West earlier this week. Image: DigiLens. back to the fundamental optics involved, the post-holiday event to in particular the waveguides inside glass- launch the latest features in their increas- – nearly 40,000 lives are lost every year Also at CES 2019 was the car parts es and headsets. ingly tech-oriented vehicles. Among this on US roads alone, among 1.25 million supplier Valeo, whose “SCALA” scanner Among those to present at Photonics year’s major draws was Toyota, whose worldwide. And before unveiling the P4, is claimed to be the only mass-produced West’s dedicated AR/VR/MR confer- US-based subsidiary Toyota Research TRI’s CEO Gil Pratt showed footage of an automotive lidar system currently on alarming three-car crash the market. The France-based compa- collected by and involv- ny signed a deal with Intel subsidiary ing one of the company’s Mobileye to develop and promote a new earlier “Platform 3.0” test autonomous vehicle safety standard vehicles, at the time in combining a multitude of sensors, in- manual mode, on the I-80 cluding lidar, with Mobileye’s mathe- interstate road close to San matical safety model. Francisco. Set against the brave new worlds of “Luckily, despite the artificial intelligence, alternative reali- severity of the crash, no- ties, and self-driving vehicles, the hum- body was injured,” said ble television might seem rather outdated Pratt. “We show you this at CES these days. But that didn’t stop now, not to wow you with Samsung launching new models based technology, but because I on another emerging photonics technolo- want to take you through gy – micro-LEDs. The Korean company’s a question that we posed 75-inch screens rely on arrays comprising to ourselves that very day: myriad tiny emitters, claiming advantages could a Toyota Guardian in terms of brightness, modularity, lifes- [TRI’s driver assistance pan, and a bezel-free design. system] have prevented or “These transformative TV displays mitigated this crash?” are made up of individual modules of The answer, he said, self-emissive micro LEDs, featuring was yes. When TRI recre- millions of inorganic red, green, and blue Toyota’s latest “Guardian” test vehicle for autonomous driving is mobbed by the media at CES 2019 in ated the scenario on a test microscopic LED chips that emit their Las Vegas. The car features high-performance lidar units in its roof section, other lidar sensors around its track, sensors on board the own light to produce brilliant colors on chassis, radar, and numerous cameras. Photo: CES. car showed that in the real screen – delivering unmatched picture ence was DigiLens, which at CES 2019 Institute (TRI) rolled out its new “P4” test crash it could have accelerated safely away quality that surpasses any display tech- launched AR smart glasses said to offer vehicle on the Las Vegas stage. from the encroaching vehicles as they ap- nology currently available on the market,” a much-improved level of form-factor, op- The P4 features high-performance proached, creating more space on the road boasted Samsung. tical efficiency (meaning longer battery lidar systems from Photonics West ex- and a safer driving “envelope”. MIKE HATCHER

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take a larger share of the components SPIE updates enabled-markets report business. Figures show core components market growing at nearly 7% For more on these and other industry trends, together with a detailed look at the On Thursday morning after the Photon- investment in Asia. The investment value to Linda Smith of Ceres Technology Ad- photonics-enabled marketplace, join me ics West exhibitor breakfast, the SPIE of private placements in Asian targets is visors. As with the investment capital, and Jennifer Douris O’Bryan for the Pho- industry team releases the latest update of substantially higher concentration in the SPIE report shows a trend of pho- tonics Industry and Public Policy Update to its biennial Industry Report. The pre- the photonics segment than in all other tonics components revenues also shifting at 9.15 am, after the Exhibitor Breakfast. sentation will focus on gains in the pho- vertical segments combined, according towards Asia, as China-based enterprises STEPHEN G. ANDERSON tonics-enabled marketplace, examine trends across major market segments, and include a review of the core photon- ics components manufacturing business. SPIE and its industry team has been providing a benchmark study for quanti- fying this complex industry since its ini- tial analysis of the photonics components manufacturing industry was unveiled at Photonics West in 2013. Since then, its biennial studies have delivered industry metrics with a robust, consistent, and transparent methodology. As diverse and dynamic as ever, the photonics industry continues to exhibit impressive growth. The business com- prises a diverse set of technologies that INTRODUCING underpin nine major market segments OFS’ AcoustiSens Single-Mode Optical Fiber for Acoustic Sensing ranging from advanced manufacturing to consumer and entertainment. Glob- al revenues from all photonics-enabled businesses and services now account for more than a 13% share of the global economy – as measured by global gross domestic product (GDP) – and the pros- pects are for continued gains across mul- tiple segments. Underlying the nine end-use market segments is the global photonics com- ponents manufacturing industry. Valued at an annual $227 billion in 2016, this element of the photonics industry is also growing. The SPIE Industry Report has tracked core components manufacturing since 2012 and projects an overall com- AcoustiSens boosts Rayleigh backscatter while maintaining low fiber attenuation pound growth rate of 6.6% from 2016 through 2018. – enables significant improvement in Distributed Acoustic Sensing (DAS) SNR. Beyond revenue growth, the industry has also seen a positive change in per- AcoustiSens groundbreaking enhancements enable improvements spective by the investment community, at the same time as a change in geographical in DAS cables for many applications: upstream and midstream oil and gas, distribution of revenues. railroads, perimeters, borders, subsea, smart highway and smart city applications. Traditionally, firms that serve end-use markets like consumer, healthcare, or de- fense have created much of the value as- sociated with photonics commerce. They include the likes of Apple, Illumina, and Thales, and do not typically see them- selves as photonics companies. None- theless, photonics components are key to these companies’ success. More recently, the technology and component providers have been able to capture a larger share SPEAK WITH THE EXPERTS! of this value, and investment in photonics Booth #1559 and photonics-enabled firms has skyrock- eted since 2012. To learn more, visit us at www.ofsoptics.com As the overall investment in photon- ics and its vertical markets has grown, so has the concentration of photonics

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the Aeolus team – to make it fly.” Lasers make the grade in Earth In fact ESA set up two new labora- tories to solve its laser issues. It called in additional support from the German observation and space exploration Aerospace Center to produce entirely new Astronomers, weather forecasters, and Earth scientists are among those technical standards, which are now being applied to all subsequent laser missions. now benefiting from the application of solid-state lasers in space. “The commercial space industry by itself could not have gone to the lengths we Even by stellar historic standards, it has Last August, the European Space Agency globe and play a key role in our quest to took,” Armandillo pointed out. been a remarkable few months for space (ESA) finally launched its wind-monitor- better understand the workings of our at- The idea of flying a wind-surveying probes and their on-board optical instru- ing Aeolus satellite. The first wind lidar mosphere,” announced ESA following the lidar in orbit was nothing new. In fact it mentation. Late 2018 saw the erstwhile instrument in space, it is based around launch of the 1.4-tonne satellite aboard a had been explored as long ago as the early Voyager 2 probe – complete with inter- a UV laser and is set to provide far more Vega rocket last year. “Importantly, this 1980s, considered at one time for the ISS. ferometer, ultraviolet spectrometer, pho- accurate and detailed monitoring of wind novel mission will also improve weather And in fact the technology developed back to-polarimeter, and dual-camera imaging speeds than was previously possible. forecasting.” then is now used to help guide rendezvous science system – finally leave the solar Attempts to understand and docking operations system. We’ve also witnessed some ex- and forecast the wind date with ISS-supplying cargo traordinary imagery and data acquisition back as far as Aristotle in spacecraft. carried out by missions such as the Parker the 4th century BC. To- Initially a high-energy Solar Probe, the close encounter between day, wind profiles sampled carbon dioxide gas laser OSIRIS-REx and asteroid Bennu, and down through the atmo- was earmarked for the ozone monitoring by the Earth-observing sphere are needed for accu- lidar role, before the mid- Sentinel-5P satellite. rate medium- to long-term 1990s development of Just weeks before Photonics West weather forecasting, and space-worthy pump laser opened its doors the imaging instru- are critical for modelling diodes opened the door ments on NASA’s New Horizons mission climate change. But until to far more compact sol- captured the unusual “lumpy snowman” Aeolus, this information id-state designs. The Aeo- form of Ultima Thule, and a couple of days was not available from lus mission was pencilled later China’s Chang’e 4 probe touched direct measurement: the in for a launch some time down on the far side of the Moon. Recent best equivalent came from after 2000. months have also seen the launch of the ground sensors and bal- Based around a con- Bepi Colombo mission to Mercury, its loon monitors giving local- ventional Nd:YAG sol- payload featuring a laser altimeter and ized point measurements, id-state laser crystal, the an ultraviolet (UV) spectroscopy probe, followed by extrapolation The ATLAS laser, part of NASA’s much-delayed ICESat-2 mission, was UV wavelength selected a laser-cooled atom experiment delivered through cloud tracking launched in September 2018. It will provide high-precision profiles of ice is seen as essential for sheets and sea ice for climate studies. Photo: NASA. to the International Space Station (ISS), or computer simulations. achieving the high level and the deployment of laser terminals to Aeolus being in orbit changes that, and But the mission has also proved to of back-scatter from both molecular and quickly transmit huge data sets back to for the first time global wind fields can be one of ESA’s most technologically de- aerosol components to provide reliable li- Earth from imaging satellites. be mapped directly, in three dimensions. manding. Problems with the “Aladin” UV dar signals. But ESA saw the first signs of In terms of photonics equipment, per- laser, in particular the damage caused to trouble in NASA’s ICESat mission, which haps most satisfying of all has been the Challenging development its system optics over an extended op- was using a UV laser to map ice. Around recent arrival of a couple of solid-state “Using revolutionary laser technology, erating period, had delayed the original the same time, ground tests on Aladin lasers on board Earth-orbiting spacecraft. Aeolus will measure winds around the launch schedule by more than a decade. began to show laser-induced contami- Thanks in part to techni- nation of optics. cal breakthroughs made The key problem was then identified: with a similar source – the out-gassing of organic molecules from green laser at the heart of Aladin’s laser equipment was accumu- NASA’s similarly delayed lating on system lenses, before being ICESat-2 mission – the Ae- carbonized by the high-energy UV laser olus mission now looks set pulses. As they grew, those deposits fur- for major success. ther absorbed the laser’s heat, distorting A couple of weeks af- and darkening the optical components. ter launch, Aeolus sent It meant that the original perfor- back its first data, and mance of the UV laser within Aladin was in November Errico Ar- nowhere close to requirements. ESA says mandillo, the retired that when it ran a prototype version of head of ESA’s optoelec- the lidar system, its laser optics degrad- tronics section, reflected ed by 50% in less than six hours of op- on the development. “To- erations – not much use for a proposed day Aeolus is returning three-year mission. more wind data than all “The first solution was to take extreme ground-based measuring precautions to remove all organics,” Ar- systems put together,” he mandillo said. “But this did not prove remarked. “But it took the entirely possible. Even at just a few parts sustained efforts of ESA per billion of organics, contamination was Laser equipment for cooling atoms in space arrived at the International Space Station in July 2018 on labs and technical experts still introduced.” board a Cygnus supply vehicle – seen here being collected by robotic arm. Photo: NASA. – in close cooperation with continued on page 27

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Earth observation continued from page 25 to benefit a range of future missions. Ala- starting to return those initial wind pro- metrics represented a significant increase For more clues the team approached din’s development has yielded ESA some files from space, NASA launched its ‘ICE- in the complexity and reliability require- users of high-energy UV lasers in terres- world-leading optics and optoelectronics Sat-2’ satellite from California’s Vanden- ments for a space-based laser system. trial applications. That included working capability, along with a set of ISO-certi- berg Air Force Base. The optical design of ATLAS splits closely with two German optics compa- fied laser development standards for other Like Aeolus, the mission – compris- the laser source into three separate pairs nies, LaserOptik and LayerTec, as well laser-based missions – starting with the ing a single-instrument laser altimeter of beams that are fired towards Earth at as experts at France’s Mégajoule facil- “EarthCARE” mission for clouds and aero- payload – was delayed and significantly different angles, such that at ground level ity – where lasers are employed to ig- sol monitoring. Pencilled in for launch in over its original budget. But it has now there is a 3.3 km gap between the beam nite nuclear fusion reactions – and the 2021, this will carry an atmospheric lidar deployed its Advanced Topographic La- pairs. This contrasts with the approach semiconductor industry. In principle, the instrument based around a 355 nm laser ser Altimeter System (ATLAS), flying in used on the original ICESat mission that answer proved remarkably simple. Inject- source to profile aerosols flew between 2003 and ing a small amount of oxygen allowed the and thin clouds. 2009 but whose laser only contamination to burn up under the heat “It’s proved an extreme- operated at 40 Hz, and of the laser, in the process cleaning the ly complex mission, and provides much denser lens. In tests, the ESA team says it saw we’ve learnt an awful lot cross-track sampling. this approach work in a matter of minutes. about lasers,” concluded For Earth scientists and Rondin, with Aeolus’s in- studies of climate change, Laser breathing strument manager Denny the altimeter should yield a Rather than redesigning Aladin to Wernham adding: “The height measurement every work on a fully pressurized basis, small fact we have a high-power 70 cm along the orbiting amounts of oxygen are released from a UV laser instrument now track, with Fibertek saying pair of 30-liter tanks. The oxygen gas working in space is tes- that elevation estimates flows close to the optical surfaces that are tament to all of the hard in sloped areas and rough exposed to the UV laser, and gradually work, ingenuity, and in- surfaces around crevasses leaks out of the instrument enclosure. ventiveness of many ded- will be much improved. “Just like us, the laser has to breathe,” icated engineers in indus- According to the IC- explained laser engineer Linda Mondin in try, ESA, and elsewhere. ESat-2 team, only about This master-oscillator power-amplifier (MOPA) laser module was launched a report by ESA. “It’s very elegant because “Aeolus is a world-first on a sounding rocket in early 2017, to carry out the first laser-cooling a dozen of the approxi- the burnt-up contaminants flow out of the mission that will hopefully experiments in microgravity. In November 2018 the German consortium mately 20 trillion photons instrument along with this oxygen, in the lead to many active laser that built it reported that 110 experiments were completed during its six that leave ATLAS with minutes of space travel. Copyright: FBH/schurian.com. form of carbon dioxide and water.” Only missions in the future, and each laser pulse return to 25 Pascals of residual oxygen pressure shows the true value of close collaboration a polar orbit at an average altitude of 290 the satellite’s telescope after a round trip is needed – just one four-thousandth of between industry and ESA to find inno- miles. Its job is to monitor annual changes that takes around 3.3 milliseconds. To standard atmospheric pressure. vative solutions to very tough technical in the height of the Greenland and Antarc- detect those scarce returning photons, the Though contamination was the key challenges.” tic ice sheets, to a precision of just 4 mm. system is equipped with a 76 cm-diame- issue facing the Aladin team, it was far “There were so many ways it could go Developed by the Virginia-based pho- ter beryllium telescope. A series of filters from the only problem. Heat produced wrong, we were worried,” recalled Ar- tonics and engineering services company ensures that only light of precisely 532 within the volume of the laser transmit- mandillo following the 2018 launch. “And Fibertek, the two flight lasers aboard IC- nm reaches the detectors, eliminating any ter also needed removal. This was solved then it worked! Those first wind profiles ESat-2 emit millijoule-scale nanosecond reflected sunlight that might influence using ‘heat pipes’, which cool the laser felt like Christmas coming early, a really pulses at 532 nm and a repetition rate of the results. by evaporating liquid and moving it to a amazing gift.” 10 kHz. In continuous operation over the Just three months after launch, ICE- space-facing radiator. three years of the mission, that equates to Sat-2 was already exceeding scientists’ Solving the various problems has ulti- ICESat-2: up and running around a trillion pulses in all – with Fib- expectations. NASA said that the satellite mately created new technology that is set Just as Aeolus and its Aladin laser were ertek saying that the tough performance continued on page 28

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Earth observation continued from page 27 kilometers, before returning to the ground. Developed by had measured the height of sea ice to within an inch, Humboldt University Berlin’s optical metrology research traced the terrain of previously unmapped Antarctic group, initial results confirmed that it was possible to valleys, surveyed remote ice sheets, and peered through carry out research on laser-cooled atoms in space, and forest canopies and shallow coastal waters. in November 2018 the German consortium reported that “ICESat-2 is going to be a fantastic tool for research it had carried out a remarkable 110 experiments on BECs and discovery, both for cryospheric sciences and other during the six minutes of space travel that were possible. disciplines,” said Tom Neumann, ICESat-2 project scien- Another diode-pumped solid-state laser currently tist at NASA’s Goddard Space Flight Center in Greenbelt, traversing the solar system sits inside an altimeter setup Maryland. Neumann and others shared the first results destined for the planet Mercury. Launched by the ESA from the mission at the American Geophysical Union’s in October, the Bepi Colombo probe is a collaboration December 2018 meeting in Washington, DC. with the Japan Aerospace Exploration Agency (JAXA). “It’s spectacular terrain,” reported Benjamin Smith, Designed and built by a Swiss-German-Spanish team a glaciologist with the University of Washington, Seat- led by engineers at the University of Bern, the altimeter tle, and member of the ICESat-2 science team. “We’re kit will be used to map Mercury’s topography and sur- able to measure slopes that are steeper than 45 degrees, face morphology in unprecedented detail, and is said to and maybe even more, all through this [Transantarctic] be the first such instrument developed for a European mountain range.” The returning photons have shown high ice plateaus, crevasses in the ice 65 feet deep, and the sharp edges of ice shelves dropping into the ocean. Those first measurements will help fill in current gaps in maps of the Ant- arctic, Smith said, although the most critical science of the ICESat-2 mission is yet to come. As researchers refine their knowledge of exactly where the instrument is pointing, they can start to measure the rise or fall of ice sheets and glaciers. “Very soon, we’ll have measure- ments that we can compare to older measurements of surface elevation,” Smith said. “And after the satellite’s been up for a year, we’ll start to be able to watch the ice sheets change over the seasons.” Cold Atom Lab Not long before the launch of the Ae- The Aladin laser, seen here in ground tests before launch, is at the heart of olus and ICESat-2 sources, another the Aeolus satellite. It is now in polar orbit, providing direct measurements of global wind patterns for improved weather forecasting. Initial results are said laser system made its way to the ISS, to be excellent. Photo: Selex-ES. where it is now carrying out quantum research inside the orbiting Cold Atom Lab (CAL). Part interplanetary mission. Based around a Q-switched, of a scientific payload that arrived in May 2018, it is nanosecond-pulsed Nd:YAG source operating at 10 Hz, based around commercial laser equipment and capable it will fire relatively high-energy (50 mJ) bursts of 1064 of trapping potassium and rubidium isotopes. nm light at the planet, and collect reflections from the By July, the space lab had produced Bose-Einstein surface around 5 ms later using a silicon avalanche pho- condensates (BECs) of rubidium atoms in orbit for the todiode, via a narrowband filter. first time, controlled by scientists on the ground at NA- Elsewhere in the solar system, NASA’s OSIRIS-REx SA’s Jet Propulsion Laboratory (JPL) in California. Rob- mission has just completed its approach to the asteroid ert Thompson, CAL project scientist and a physicist at Bennu, where it is now in close orbit. Ultimately, it is set JPL, said at the time. “It’s been a long, hard road to get to grab a sample from the surface of the orbiting rock here, but completely worth the struggle, because there’s and bring it back to Earth, but before that Bennu had so much we’re going to be able to do with this facility.” to be mapped in considerable detail to ensure that the Although shrinking the BEC-making equipment spacecraft could be maneuvered into exactly the right to the size demanded for launch to the ISS has been a orbit to achieve the close fly-by. huge challenge, the advantages of the environment are That operation relied on another laser altimeter fea- enormous, from the point of view of quantum experi- turing a lidar scanner, to generate a detailed three-di- mentation. Unlike on Earth, the persistent microgravity mensional map of Bennu’s shape. Built by the Canadian allows scientists to observe individual BECs for 5-10 Space Agency, it will help the OSIRIS-REx team identify seconds at a time, and to repeat measurements for up the best location from which to grab a sample. Two lasers to six hours every day. are on board: a high-energy source to scan the asteroid In fact this was not quite the first cold atom experi- at distances between 7.5 km and 1 km from the surface, ment in space. In January 2017 the “MAIUS-1” sounding and a second low-energy emitter that can be used for rocket launched a diode laser system for laser cooling rapid time-of-flight imaging down to 225 m. and rubidium atom interferometry to an altitude of 243 MIKE HATCHER

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Changing how we see light On Tuesday, a panel of LED lighting Jay Shuler, Director of Product Mar- Nanoscribe’s experts provided examples of the inno- keting at Xicato, opened the session new Photonic vative applications that go well beyond talking about general trends in LED Professional GT2 3D the simple replacement of conventional lighting that are going “beyond on and system is changing the method of producing micro-optical sources with more efficient LEDs. The off.” As an example, he showed a quick components. This AM technology makes panel offered insights into the technol- case study being done at the Smithso- polymer masters for serial production. (Booth #366) Photo: Matthew Peach ogy innovations that are providing new nian’s National Portrait Gallery using benefits and capabilities that were never controlled lighting to “create a whole achievable with conventional sources. new viewing experience for visitors.” In his opening remarks, panel mod- Instead of constant bright light being ‘Speedier, smarter’ 3D world erator Robert V. Steele noted that the shown on each picture, the lights remain Faster speeds and more detail are must-do to go smaller, to 10 microns in diameter. lighting market is undergoing a trans- in dim lighting until someone walks in items for the future of 3D printing. Taking She admitted powder bed will remain formation of a magnitude not seen since front of the portrait, then the lighting six days to grind out a single part is unac- the standard. “It is necessary, and we the invention of the incandescent bulb. slowly increases to full light, boosting the ceptable, a panel of four 3D experts agreed. can make very complicated parts can be Energy efficiency and color as the picture comes Industry panelists saw the needed 3D made. But it’s just a step to whatever the cost savings have been into view. After the viewer evolution on the horizon. The 3D Print- future technologies will be. In 20 years, the main drivers of this walks away, the light slow- ing and Industry 4.0 panel included Ralf perhaps there will be technologies other transformation, but ly dims. “This makes for a Kimmel of Trumpf; Melissa Orme of than powder-bed fusion that will be faster, other factors, such as more interesting display,” Morf3D; Behrang Poorganji, of GE Ad- with better resolution, and finer details. light quality, color tun- said Shuler. “This also ditive; and Lynn Sheehan of Allagi Inc. “We need 3D to be able to make parts ing, and controllability, helps preserve the art.” Kimmel said that if 3D can achieve faster, at higher resolution, and cheaper. have become equally Benno Spinger from Lu- higher productivity, that will mean faster I’m certain new technologies will point important in moving mileds Germany discussed printing, “and the payoff will be a shorter the way to reach those goals.” the market forward. Lumiled’s work with adap- build time. Multiple lasers and better per- At GE Additive, Poorganji said 3D ad- LED technology em- tive headlighting enabled forming scanner systems are required for ditive manufacturing is “the new revolu- bodied in lamps and lu- by pixelating LED sources the next step,” Kimmel said. “We will see tion,” from medical to automotive apps. minaires have captured Benno Spinger of Lumileds – in particular, adaptive multiple lasers working on many scan- “We are expanding our inventories,” he more than 50% of the Germany discusses adaptive driving beam technology ners, well coordinated and synchronized, said, using power from 25-100 µm, and $80 billion worldwide driving beam technology. for road vehicles. “At the Photo: Adam Resnick with better control of the power over the 3D has created a $5 billion cost efficiency. lighting market, and moment, headlamps are beam path. GE analyzed an A-CT7 aircraft engine the near-complete penetration of this really complicated with the LEDs, it’s “Control over power distribution to- and found that 70 percent of the engine market with LED sources is in sight. more of an electro-mechanical system,” gether with scanner performance is key.” could be 3D printed. And they found that “Several technology companies are said Spinger. “These systems can make Today, if a scanner comes to an edge, engines with many parts made in a sin- now working on controls of various types a complex system much simpler.” it slows down, and then has to accelerate gle 3D printing have more durability, can to control light levels in buildings with The final speaker, Thor Scordalis, again, he explained. “You must correlate save fuel, and weigh less, with up to 60 occupancy sensors, daylight sensors, General Manager-Americas at Leo- all this, the speed, power, and movement percent reduction in time to market. etc.,” said Steele, a solid-state lighting tek LLC, talked about what he termed position. There is a lot to do. At Allagi, Sheehan said a hardware set consultant. “Lumileds and Osram are the “Non-Energy Benefits” of LED lighting. “It is happening, but we’re not on a per- called Opticus for monitoring additive major LED suppliers working on adaptive These included improved safety and fect level. To be more productive, you need manufacturing makes a digital twin of a lighting; European auto companies such health of the user, reduced operating and to add more operating systems.” part being created. It can stop the process as Audi and Mercedes are taking the lead maintenance costs, as well as increased For Orme, the current powder bed ap- and even fix the problem, he said. on incorporating automotive forward productivity and comfort for users. proach, now at 50 microns diameter, needs FORD BURKHART lighting technology into their cars.” KAREN THOMAS

IMPLANTED LEDs HELP MANAGE ORGAN DYSFUNCTION Optical mouse: New soft, wireless implants can mon- light to reduce the urge to urinate. That through a change in resistance, the ex- Soft implantable optoelectronics itor and modulate organ behavior approach, Rogers said, could treat in- tent of bladder filling at any given time. A allow closed-loop using LED light, a demonstration continence and an overactive bladder. battery-free control unit in the abdomen control of organ at Photonics West revealed. Im- The wireless systems provide closed- captures that data and sends it to an ex- function. Credit: Rogers Group / plants remove the tethers used in loop control over the nerves that gov- ternal PC for an assessment of bladder Northwestern other nerve-stimulation systems. ern organ function and “can eliminate activity using advanced data analytics. University. The technology will be useful in disease or dysfunction without drugs,” “If overactivity is identified, then a deep brain research, said John Rogers, Rogers said. signal is wirelessly passed back to the a professor of materials science and en- His approach uses thin, battery-free control unit, which then causes the LED gineering, biomedical engineering, and implants that control an overactive blad- to activate,” Rogers said. “The light in- neurological surgery at Northwestern der in animal models using a microscale hibits the activity of bladder nerve end- University and keynote speaker on wire- LED. It emits photons that illuminate ings, thereby preventing voiding.” less optoelectronics at the Optogenetics nerves in the bladder, where injected Rogers’ team has developed an app & Optical Manipulation Conference. proteins make the cells sensitive to light. that runs on a phone to display the data In one project, his system was used to Whenever the system detects fre- and the system’s recommendation, and send and receive signals from the blad- quent voiding events, the sensing relies can let users intervene in the decision der. The system detected an overactive on a soft band that wraps around the to stimulate or not. bladder in a lab animal, and used LED bladder to electronically determine, FORD BURKHART

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OUTSMARTING Frequency-modulated lidar sensor TUMORS: LASERS enhances control of autonomous vehicles BOOST T CELLS Insight LiDAR has developed Digital Co- ware-programmable waveforms that hanced by Insight’s proprietary true sol- To fight the toughest cancers – those in the herent LiDAR, a chip-scale, long-range have been used in FMCW radar for over id-state, fast-axis scan architecture. This pancreas – an evolving method combines lidar sensor targeted at the autonomous 40 years. Insight LiDAR’s FMCW sensor unique feature enables Insight LiDAR tumor-killing lasers to bolster the immune vehicle market. Digital Coherent LiDAR offers a factor of 10 to 100 higher sensi- to both precisely steer the beam and en- system by boosting T cells. is based on Frequency Modulated Con- tivity than ToF lidar while simultane- crypt the critical fast-scan axis through The strategy, called immunotherapy, tinuous Wave (FMCW) technology, which ously offering direct Doppler velocity software alone, with no moving parts. has been developed by Wei R. Chen of the offers certain advantages over the cur- measurement. “It’s an interesting time in this mar- University of Central Oklahoma. Since rent generation of Time-of-Flight (ToF) The higher sensitivity, enabled by ket,” commented Michael Minneman, 1995, Chen’s team has been developing a lidar sensors. This company is a spin- FMCW detection, drives Digital Coherent CEO of Insight Photonic Solutions. “Level combination of targeted laser photother- out of Insight Photonic Solu- 4 and 5 autonomy needs a apy and injection of an immune system tions, a developer of highly level of performance, range, stimulant that releases new antigens. linear, swept-wavelength la- resolution, frame rate, and “We needed to find a mechanism to ac- ser sources for imaging and immunity that legacy ToF tivate the immune system to fight against sensing applications. sensors just can’t deliver.” the cancer,” Chen said. “When a tumor ap- Autonomous vehicles re- Couple that to cost goals pears, antigens stimulate T cells to kill it. quire a variety of sensors to that can only be met with “But the tumor is very smart, and interpret the world around a true all-semiconductor sends out checkpoints to deactivate the them and to make accurate, solution and you see the T cells. Immunophotonics counters with timely decisions. While nine- challenge. “We’ve been de- a checkpoint inhibitor, to break down the ty-three percent of autono- signing and manufacturing checkpoint so T cells can be activated to mous vehicle experts inter- the core technology in this kill the cancer cells.” viewed by UBS investment FMCW lidar sensor for Pancreatic cancer, with few early symp- bank believe that lidar is a more than 10 years,” com- toms, has a low survival rate, leaving up to prerequisite for autonomous Screen saver: The long-range lidar sensor targeted at the mented Dr. Chris Wood, 80 percent of victims with low levels of T autonomous vehicle market. Photo: Joey Cobbs vehicles, today’s legacy lidar head of Insight LiDAR’s cells and hopeless as the tumor migrates. sensors either do not provide the perfor- LiDAR’s long-range capability; 200 m to development and technology. Chen’s approach gives the checkpoint in- mance or the price needed for wide-scale dim (<10 percent reflectivity) objects like “Lidar designers have long known the hibitor more T cells to work with. deployment. Legacy lidar either does not car tires, and 250 m or more to vehicle advantages of FMCW detection, but the His team has started a company called have the ability to see faint objects at a bodies, trees, and other obstacles. critical laser sources have been large and Immunophotonics Inc. in St. Louis, with distance, or it cannot meet industry cost Direct Doppler velocity measure- expensive. Over the past ten years, we’ve subsidiaries in China and Switzerland. targets, due to expensive laser sources ment enables much faster recognition developed and refined unique, patented The biotech company grew out of a meet- and fiber amplifiers. and classification of objects, especially methods to manufacture and control the ing of future partners at the 2009 SPIE Insight’s Digital Coherent LiDAR critical for safe level 4 and 5 autonomous laser sources driving world-class perfor- Photonics West meeting. Chen said get- was developed based on more sensitive vehicle operation. mance in a tiny chip-scale package.” ting the team’s approach to markets is FMCW detection techniques and soft- Digital Coherent LiDAR is further en- MATTHEW PEACH about five years down the road. FORD BURKHART

BiOS Hot Topics continued from page 07 Laboratory at the National University of Singapore with spectroscopic cancer de- BRIGHT ideas tection. He and his team have developed Clare Elwell of University College London an integrated Raman endoscopy and wide- opened the session with her research us- field imaging technique for real-time in ing new optical imaging techniques to un- vivo tissue Raman measurements during derstand the human brain, including the clinical endoscopy. PUBLISHED BY SPIE, 1000 20th Street Gates Foundation-funded BRIGHT (BRain “We developed an endoscope-based Bellingham WA 98225 USA Imaging for Global HealTh) project. She autofluorescence imaging and spectrosco- Tel: +1 360 676 3290 and her team use functional near infrared py system for in vivo tissue diagnosis and www.spie.org spectroscopy (fNIRS) to investigate the characterization,” said Huang. “Prelimi- Samuel Achilefu, Washington University EDITORIAL impact of malnutrition on infant brain de- nary results show that combining spec- School of Medicine, with Jim Oschmann. Original Content Ltd. velopment in The Gambia, and conducting troscopy with imaging techniques can Photo: Stacey Crockett Tel: +44 (0)117 939 4887 the first brain imaging of infants in Africa. improve both the diagnostic sensitivity mer’s disease, she noted. ADVERTISING SALES “We were using NIRS for decades in and specificity for discriminating early Alexander Vahrmeijer of Leiden Uni- Lucent Media high-resource areas, unaware of the need cancer from normal tissue.” versity Medical Center explained how Tel: +44 (0)117 905 5330 for it in a global health project,” said Elwell. “We’ve been to the moon, but still hav- targeted molecular imaging can facilitate PRODUCTION & PRINTING Elwell noted how NIRS studies of the en’t been able to see the lymphatics,” said precision surgery. “Optical imaging that Tradeshow Media Partners 200 Valley Drive, Suite 36 developing brain are paving the way for Eva Sevick-Muraca of University of Texas exploits invisible near infrared fluorescent Brisbane, CA 94005 early markers of autism. And following its Houston in her opening remarks on aging light has the potential to improve cancer Tel: +1 415 371 1525 successful implementation in resource- as seen through the lens of translational surgery, minimize the time patients are poor settings, NIRS is now finding biomedical optics. There is strong evi- under anesthesia, and lower health-care application as a brain-imaging tool in dence that chronic inflammation contrib- costs largely by way of its improved con- ©2019 Society of Photo-Optical global health studies. utes to a number of conditions prevalent trast and depth of tissue penetration rela- Instrumentation Engineers (SPIE). Zhiwei Huang discussed the work with aging, including peripheral vascular tive to visible light,” said Vahrmeijer. All rights reserved. of his group in the Optical Bioimaging disease, rheumatoid arthritis, and Alzhei- KAREN THOMAS

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