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Geoffrey Wilkinson
THE LONG SEARCH FOR STABLE TRANSITION METAL ALKYLS Nobel Lecture, December 11, 1973 by G EOFFREY W ILKINSON Imperial College of Science & Technology, London, England Chemical compounds in which there is a single bond between a saturated car- bon atom and a transition metal atom are of unusual importance. Quite aside from the significance and role in Nature of the cobalt to carbon bonds in the vitamin B 12 system and possible metal to carbon bonds in other biological systems, we need only consider that during the time taken to deliver this lec- ture, many thousands, if not tens of thousands of tons of chemical compounds are being transformed or synthesised industrially in processes which at some stage involve a transition metal to carbon bond. The nonchemist will pro- bably be most familiar with polyethylene or polypropylene in the form of do- mestic utensils, packaging materials, children’s toys and so on. These materials are made by Ziegler-Natta* or Philipps’ catalysis using titanium and chro- mium respectively. However, transition metal compounds are used as catalysts in the synthesis of synthetic rubbers and other polymers, and of a variety of simple compounds used as industrial solvents or intermediates. For example alcohols are made from olefins, carbon monoxide and hydrogen by use of cobalt or rhodium catalysts, acetic acid is made by carbonylation of methanol using rhodium catalysts and acrylonitrile is dimerised to adiponitrile (for nylon) by nickel catalysts. We should also not forget that the huge quantities of petroleum hydrocarbons processed by the oil and petrochemical industry are re-formed over platinum, platinum-rhenium or platinum-germanium sup- ported on alumina. -
Goverdhan Mehta Chemistry - a 21St Century Science for Global Sustainability: Is It Future Ready?
Goverdhan Mehta Chemistry - A 21st Century Science for Global Sustainability: Is it future ready? Goverdhan Mehta A ‘selfie’ with theSchool chemical of Chemistry world…… University of Hyderabad National Geophysical Research Institute, CSIR Foundation Day, Sept. 27, 2019 Introducing Chemistry through the Lens of Earth's Systems: What Role Can Systems Thinking Play in Developing Chemically and Environmentally Literate Citizens? J. Kornfeld, S. Stokoe. J. Chemical Education 2019, 96, 2910-2917 A bouquet of ‘matters’ that matter New symbols Passion Sustainability Legacies Ethics & values Responsible Connections Systems Directions Humility Ideas & icons Inspirations Un mélange de beaucoup de choses “Chemistry ought not to be for chemists alone” - Miguel de Unamuno ‘…Life, Universe and Everything’ Chemistry – a source of happiness…. Chem -Connectome ‘...I feel sorry for people who don’t know anything about chemistry. They are missing an important source of happiness....’ - Linus Pauling 1901-1994 S.A. Matlin, G. Mehta, H. Hopf. Chemistry Embraced by All. Science 2015, 347, 1179 Chemistry is in everything. and everything is in it, it is the basis of life, without it we wouldn't exist. Green tea has ~ 200 chemicals Coffee has ~ 1000 chemicals Wine has >1000 chemicals Light cigarette ~ 4000 chemicals Chemistry is ubiquitous/omnipresent Chemistry – Tracing the roots and to the present BCE Art & craft of mixing substances A giant knowledge leap Alchemy to modern science Evidence based science Discipline in a Table - systematization Mendeleev’s Periodic Law ‘Molecularization’ of chemical matter 20th Century A century of evolutionary march of chemistry 20h Century Value added products from almost anything “Utility science” and everything Molecular understanding of life processes and “Core Science” chemical matter Interdisciplinarity in forefront “Integrative Science” Resource stressed planet “Sustainability Science” 21st Century S. -
Chemistry in Italy During Late 18Th and 19Th Centuries
CHEMISTRY IN ITALY DURING LATE 18TH AND 19TH CENTURIES Ignazio Renato Bellobono, CSci, CChem, FRSC LASA, Department of Physics, University of Milan. e-mail add ress : i.bell obon o@ti scali.it LASA, Dept.Dept. ofPhysics, Physics, University of Milan The birth of Electrochemistry Luigi Galvani, Alessandro Volta, and Luigi Valentino Brugnatelli From Chemistry to Radiochemistry The birth of Chemistry and Periodic Table Amedeo Avogadro and Stanislao Cannizzaro Contributions to Organic Chemistry LASA, Dept.Dept. ofPhysics, Physics, University of Milan 1737 At the Faculty of Medicine of the Bologna University, the first chair of Chemistry is establishedestablished,,andandassigned to Jacopo Bartolomeo BECCARI (1692-1766). He studied phosphorescence and the action of light on silver halides 1776 In some marshes of the Lago Maggiore, near AngeraAngera,, Alessandro VOLTA ((17451745--18271827),),hi gh school teacher of physics in Como, individuates a flammable gas, which he calls aria infiammabile. Methane is thus discovereddiscovered.. Two years laterlater,,heheis assignedassigned,,asas professor of experimental phihysicscs,,toto the UiUniversi ty of PiPavia LASA, DtDept. of PhPhys icscs,, University of Milan 1778 In aletter a letter to Horace Bénédict de Saussure, aaSwissSwiss naturalist, VOLTA introduces, beneath that of electrical capacitycapacity,, the fundamental concept of tensione elettrica (electrical tension), exactly the name that CITCE recommended for the difference of potential in an electrochemical cell. 17901790--17911791 VOLTA anticipatesanticipates,,bybyabout 10 yearsyears,,thethe GAYGAY--LUSSACLUSSAC linear de ppyendency of gas volume on tem pp,erature, at constant pressurepressure,,andandafew a fewyears later ((17951795)) anticipatesanticipates,,byby about 6years 6 years,,thethe soso--calledcalled John Dalton’s rules ((18011801))ononvapour pressure LASA, Dept.Dept. -
EXPLORING NEW ASYMMETRIC REACTIONS CATALYSED by DICATIONIC Pd(II) COMPLEXES
EXPLORING NEW ASYMMETRIC REACTIONS CATALYSED BY DICATIONIC Pd(II) COMPLEXES A DISSERTATION FOR THE DEGREE OF DOCTOR OF PHILOSOPHY FROM IMPERIAL COLLEGE LONDON BY ALEXANDER SMITH MAY 2010 DEPARTMENT OF CHEMISTRY IMPERIAL COLLEGE LONDON DECLARATION I confirm that this report is my own work and where reference is made to other research this is referenced in text. ……………………………………………………………………… Copyright Notice Imperial College of Science, Technology and Medicine Department Of Chemistry Exploring new asymmetric reactions catalysed by dicationic Pd(II) complexes © 2010 Alexander Smith [email protected] This publication may be distributed freely in its entirety and in its original form without the consent of the copyright owner. Use of this material in any other published works must be appropriately referenced, and, if necessary, permission sought from the copyright owner. Published by: Alexander Smith Department of Chemistry Imperial College London South Kensington campus, London, SW7 2AZ UK www.imperial.ac.uk ACKNOWLEDGEMENTS I wish to thank my supervisor, Dr Mimi Hii, for her support throughout my PhD, without which this project could not have existed. Mimi’s passion for research and boundless optimism have been crucial, turning failures into learning curves, and ultimately leading this project to success. She has always been able to spare the time to advise me and provide fresh ideas, and I am grateful for this patience, generosity and support. In addition, Mimi’s open-minded and multi-disciplinary approach to chemistry has allowed the project to develop in new and unexpected directions, and has fundamentally changed my attitude to chemistry. I would like to express my gratitude to Dr Denis Billen from Pfizer, who also provided a much needed dose of optimism and enthusiasm in the early stages of the project, and managed to arrange my three month placement at Pfizer despite moving to the US as the department closed. -
The Correspondence of Julius Haast and Joseph Dalton Hooker, 1861-1886
The Correspondence of Julius Haast and Joseph Dalton Hooker, 1861-1886 Sascha Nolden, Simon Nathan & Esme Mildenhall Geoscience Society of New Zealand miscellaneous publication 133H November 2013 Published by the Geoscience Society of New Zealand Inc, 2013 Information on the Society and its publications is given at www.gsnz.org.nz © Copyright Simon Nathan & Sascha Nolden, 2013 Geoscience Society of New Zealand miscellaneous publication 133H ISBN 978-1-877480-29-4 ISSN 2230-4495 (Online) ISSN 2230-4487 (Print) We gratefully acknowledge financial assistance from the Brian Mason Scientific and Technical Trust which has provided financial support for this project. This document is available as a PDF file that can be downloaded from the Geoscience Society website at: http://www.gsnz.org.nz/information/misc-series-i-49.html Bibliographic Reference Nolden, S.; Nathan, S.; Mildenhall, E. 2013: The Correspondence of Julius Haast and Joseph Dalton Hooker, 1861-1886. Geoscience Society of New Zealand miscellaneous publication 133H. 219 pages. The Correspondence of Julius Haast and Joseph Dalton Hooker, 1861-1886 CONTENTS Introduction 3 The Sumner Cave controversy Sources of the Haast-Hooker correspondence Transcription and presentation of the letters Acknowledgements References Calendar of Letters 8 Transcriptions of the Haast-Hooker letters 12 Appendix 1: Undated letter (fragment), ca 1867 208 Appendix 2: Obituary for Sir Julius von Haast 209 Appendix 3: Biographical register of names mentioned in the correspondence 213 Figures Figure 1: Photographs -
Former Fellows Biographical Index Part
Former Fellows of The Royal Society of Edinburgh 1783 – 2002 Biographical Index Part Two ISBN 0 902198 84 X Published July 2006 © The Royal Society of Edinburgh 22-26 George Street, Edinburgh, EH2 2PQ BIOGRAPHICAL INDEX OF FORMER FELLOWS OF THE ROYAL SOCIETY OF EDINBURGH 1783 – 2002 PART II K-Z C D Waterston and A Macmillan Shearer This is a print-out of the biographical index of over 4000 former Fellows of the Royal Society of Edinburgh as held on the Society’s computer system in October 2005. It lists former Fellows from the foundation of the Society in 1783 to October 2002. Most are deceased Fellows up to and including the list given in the RSE Directory 2003 (Session 2002-3) but some former Fellows who left the Society by resignation or were removed from the roll are still living. HISTORY OF THE PROJECT Information on the Fellowship has been kept by the Society in many ways – unpublished sources include Council and Committee Minutes, Card Indices, and correspondence; published sources such as Transactions, Proceedings, Year Books, Billets, Candidates Lists, etc. All have been examined by the compilers, who have found the Minutes, particularly Committee Minutes, to be of variable quality, and it is to be regretted that the Society’s holdings of published billets and candidates lists are incomplete. The late Professor Neil Campbell prepared from these sources a loose-leaf list of some 1500 Ordinary Fellows elected during the Society’s first hundred years. He listed name and forenames, title where applicable and national honours, profession or discipline, position held, some information on membership of the other societies, dates of birth, election to the Society and death or resignation from the Society and reference to a printed biography. -
Synthesis and Applications of Derivatives of 1,7-Diazaspiro[5.5
Synthesis and Applications of Derivatives of 1,7-Diazaspiro[5.5]undecane. A Thesis Submitted by Joshua J. P. Almond-Thynne In partial fulfilment of the requirements for the degree of Doctor of Philosophy Department of Chemistry Imperial College London South Kensington London, SW7 2AZ October 2017 1 Declaration of Originality I, Joshua Almond-Thynne, certify that the research described in this manuscript was carried out under the supervision of Professor Anthony G. M. Barrett, Imperial College London and Doctor Anastasios Polyzos, CSIRO, Australia. Except where specific reference is made to the contrary, it is original work produced by the author and neither the whole nor any part had been submitted before for a degree in any other institution Joshua Almond-Thynne October 2017 Copyright Declaration The copyright of this thesis rests with the author and is made available under a Creative Commons Attribution Non-Commercial No Derivatives licence. Researchers are free to copy, distribute or transmit the thesis on the condition that they attribute it, that they do not use it for commercial purposes and that they do not alter, transform or build upon it. For any reuse or redistribution, researchers must make clear to others the licence terms of this work. 2 Abstract Spiroaminals are an understudied class of heterocycle. Recently, the Barrett group reported a relatively mild approach to the most simple form of spiroaminal; 1,7-diazaspiro[5.5]undecane (I).i This thesis consists of the development of novel synthetic methodologies towards the spiroaminal moiety. The first part of this thesis focuses on the synthesis of aliphatic derivatives of I through a variety of methods from the classic Barrett approach which utilises lactam II, through to de novo bidirectional approaches which utilise diphosphate V and a key Horner-Wadsworth- Emmons reaction with aldehyde VI. -
Milestones and Personalities in Science and Technology
History of Science Stories and anecdotes about famous – and not-so-famous – milestones and personalities in science and technology BUILDING BETTER SCIENCE AGILENT AND YOU For teaching purpose only December 19, 2016 © Agilent Technologies, Inc. 2016 1 Agilent Technologies is committed to the educational community and is willing to provide access to company-owned material contained herein. This slide set is created by Agilent Technologies. The usage of the slides is limited to teaching purpose only. These materials and the information contained herein are accepted “as is” and Agilent makes no representations or warranties of any kind with respect to the materials and disclaims any responsibility for them as may be used or reproduced by you. Agilent will not be liable for any damages resulting from or in connection with your use, copying or disclosure of the materials contained herein. You agree to indemnify and hold Agilent harmless for any claims incurred by Agilent as a result of your use or reproduction of these materials. In case pictures, sketches or drawings should be used for any other purpose please contact Agilent Technologies a priori. For teaching purpose only December 19, 2016 © Agilent Technologies, Inc. 2016 2 Table of Contents The Father of Modern Chemistry The Man Who Discovered Vitamin C Tags: Antoine-Laurent de Lavoisier, chemical nomenclature Tags: Albert Szent-Györgyi, L-ascorbic acid He Discovered an Entire Area of the Periodic Table The Discovery of Insulin Tags: Sir William Ramsay, noble gas Tags: Frederick Banting, -
RSC Branding
Royal Society of Chemistry National Chemical Landmarks Award Honouree Location Inscription Date The Institute of Cancer Research, Chester ICR scientists on this site and elsewhere pioneered numerous new cancer drugs from 10 Institute of Cancer Beatty Laboratories, 237 the 1950s until the present day – including the discovery of chemotherapy drug December Research Fulham Road, Chelsea carboplatin, prostate cancer drug abiraterone and the genetic targeting of olaparib for 2018 Road, London, SW3 ovarian and breast cancer. 6JB, UK The Institute of Cancer ICR scientists on this site and elsewhere pioneered numerous new cancer drugs from 10 Research, Royal Institute of Cancer the 1950s until the present day – including the discovery of chemotherapy drug December Marsden Hospital, 15 Research carboplatin, prostate cancer drug abiraterone and the genetic targeting of olaparib for 2018 Cotswold Road, Sutton, ovarian and breast cancer. London, SM2 5NG, UK Ape and Apple, 28-30 John Dalton Street was opened in 1846 by Manchester Corporation in honour of 26 October John Dalton Street, famous chemist, John Dalton, who in Manchester in 1803 developed the Atomic John Dalton 2016 Manchester, M2 6HQ, Theory which became the foundation of modern chemistry. President of Manchester UK Literary and Philosophical Society 1816-1844. Chemical structure of Near this site in 1903, James Colquhoun Irvine, Thomas Purdie and their team found 30 College Gate, North simple sugars, James a way to understand the chemical structure of simple sugars like glucose and lactose. September Street, St Andrews, Fife, Colquhoun Irvine and Over the next 18 years this allowed them to lay the foundations of modern 2016 KY16 9AJ, UK Thomas Purdie carbohydrate chemistry, with implications for medicine, nutrition and biochemistry. -
Early Russian Organic Chemists and Their Legacy
SpringerBriefs in Molecular Science Early Russian Organic Chemists and Their Legacy Bearbeitet von David Lewis 1. Auflage 2012. Taschenbuch. xii, 136 S. Paperback ISBN 978 3 642 28218 8 Format (B x L): 15,5 x 23,5 cm Gewicht: 237 g Weitere Fachgebiete > Chemie, Biowissenschaften, Agrarwissenschaften > Chemie Allgemein > Geschichte der Chemie Zu Inhaltsverzeichnis schnell und portofrei erhältlich bei Die Online-Fachbuchhandlung beck-shop.de ist spezialisiert auf Fachbücher, insbesondere Recht, Steuern und Wirtschaft. Im Sortiment finden Sie alle Medien (Bücher, Zeitschriften, CDs, eBooks, etc.) aller Verlage. Ergänzt wird das Programm durch Services wie Neuerscheinungsdienst oder Zusammenstellungen von Büchern zu Sonderpreisen. Der Shop führt mehr als 8 Millionen Produkte. Chapter 2 Beginnings 2.1 Introduction At the start of the twentieth century, organic chemistry was not yet 75 years old as a separate and legitimate sub-discipline of the science. Considerable progress had been made in these first seven decades, and the stage was set for the dramatic advances in the science to come in the following century. Most practicing organic chemists are familiar with many of the great German, French and English organic chemists whose work helped the fledgling discipline grow, but few are familiar with the role that Russian organic chemists of the nineteenth and early twentieth century played in the development of the science. And this is in spite of the fact that many of the named rules and reactions that one studies in the first course in organic chemistry are, in fact, of Russian origin. It is the intent of this book to help rectify that deficiency. -
NATURE 591 ACOUSTICAL QUANTA and the Zontalline at the 'Epoch' T
No. 4044 May 3, 1947 NATURE 591 ACOUSTICAL QUANTA AND THE zontalline at the 'epoch' t. These are extreme cases. In general, signals cannot be represented by lines ; THEORY OF HEARING but it is possible to associate with them a certain characteristic rectangle or 'cell' by the following By DR. D. GABOR process, which at first sight might perhaps appear British Thomson-Houston Co. Research Laboratory, Rugby somewhat complicated. Consider a given signal described as s(t) in 'time N popular expositions of wave mechanics, acoustical language' and by its Fourier transform S(f) in I illustrations have been used by several authors, 'frequency language'. If s(f) is real, S(j) will be in with particular success by Lande1 • In a recent paper general complex, and the spectrum will extend over on the "Theory of Communication"• I have taken both ppsitive and negative frequencies. This creates the opposite course. Acoustical phenomena are dis an unwelcome asymmetry between the two repre cussed by mathematical methods closely related to sentations, which can be eliminated by operating those of quantum theory. While in physical acoustics with a complex signal ljl(t) = s(t) + icr(t), where cr(t) a new formal approach to old problems cannot be is the Hilbert transform of s(t), instead of with the expected to reveal much that is not already known, real signals(t). This choice makes the Fourier trans the position in subjective acoustics is rather different. form 'P(f) of ljl(t) zero for all negative frequencies. In fact, the new methods have already proved their Next we define the 'energy density' of the signal as heuristic value, and can be expected to throw more ljlljl*, where the asterisk denotes the conjugate com light on the theory of hearing. -
Streamlining Alloy Design and Thermo-Mechanical Processing Parameters for High Strength Line Pipe Steels and Hot Rolled Microall
University of Texas at El Paso DigitalCommons@UTEP Open Access Theses & Dissertations 2018-01-01 Streamlining Alloy Design And Thermo- Mechanical Processing Parameters For High Strength Line Pipe Steels And Hot Rolled Microalloyed Steels: Process - Structure - Property Paradigm Venkata Vignesh Natarajan University of Texas at El Paso, [email protected] Follow this and additional works at: https://digitalcommons.utep.edu/open_etd Part of the Materials Science and Engineering Commons, and the Mechanics of Materials Commons Recommended Citation Natarajan, Venkata Vignesh, "Streamlining Alloy Design And Thermo-Mechanical Processing Parameters For High Strength Line Pipe Steels And Hot Rolled Microalloyed Steels: Process - Structure - Property Paradigm" (2018). Open Access Theses & Dissertations. 129. https://digitalcommons.utep.edu/open_etd/129 This is brought to you for free and open access by DigitalCommons@UTEP. It has been accepted for inclusion in Open Access Theses & Dissertations by an authorized administrator of DigitalCommons@UTEP. For more information, please contact [email protected]. STREAMLINING ALLOY DESIGN AND THERMO-MECHANICAL PROCESSING PARAMETERS FOR HIGH STRENGTH LINE PIPE STEELS AND HOT ROLLED MICROALLOYED STEELS: PROCESS – STRUCTURE – PROPERTY PARADIGM VENKATA VIGNESH NATARAJAN Doctoral Program in Materials Science and Engineering APPROVED: Devesh Misra, Ph.D., Chair Srinivasa Rao Singamaneni, Ph.D. Guikuan Yue, Ph.D. Charles Ambler, Ph.D. Dean of the Graduate School Copyright © by Venkata Vignesh Natarajan 2018 DEDICATION