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page numbers in bold type relate to monograph titles Index A769 Index Page numbers in bold type relate to monograph titles. Pages – Vol I: i – xxviii, (Preliminaries and Introduction) 1 – 1172, (General Notices and Monographs) Pages – Vol II: xxix – xxxvi, (Preliminaries) 1173 – 2252, (General Notices and Monographs) Pages – Vol III: xxxvii – xliv, (Preliminaries) 2253 – 3794, (General Notices and Monographs) Pages – Vol IV: xlv – lii, (Preliminaries) 3795 – 3828, (General Notices) S1 – S134, (Spectra) A1 – A768, (Appendices; Supplementary Chapters) page numbers in bold type relate to monograph titles Index A771 Acetate–edetate Buffer Solution pH 5.5, Aciclovir Tablets, 2341 A A141 Aciclovir Tablets, Dispersible, 2341 Abbreviated, A519 Acetates, Reactions of, A239 Acicular, A449 Adjectives, A519 Acetazolamide, 52,S5 Acid Blue 92, A19 Anions, A519 Acetazolamide Tablets, 2336 Acid Blue 92 Solution, A19 Cations, A519 Acetic Acid, A17 Acid Blue 83, A19 Preparations, A519 Acetic Acid (6 per cent), 54 Acid Blue 93 Solution, A19 Titles of Monographs, A519 Acetic Acid (33 per cent), 55 Acid Blue 90, A19 Abbreviated Titles, Status of, 7, 1179, Acetic Acid, Anhydrous, A18 Acid Gentian Mixture, 3585 2259, 3801 Acetic Acid, Deuterated, A46 Acid Gentian Oral Solution, 3585 Abnormal Toxicity, Test for, A354 Acetic Acid, Dilute, A18 Acid Potassium Iodobismuthate About, definition of, 5, 1177, 2257, Acetic Acid, Dilute, see Acetic Acid Solution, A100 3799 (6 per cent) Acid Value, A275 Absolute Alcohol, see Ethanol Acetic Acid, Glacial, 54, A18 Acid/base Indicators, A764 Absolute Ethanol, A56 Acetic Acid in Synthetic Peptides, Acid-base titrations, A763 Absolute Ethanol R1, A56 Determination of, A267 Acidified Chloroform, A38 Absolute viscometers, A228-229 Acetic Acid VS, A130 Acidified Dichloromethane, A48 Absorbable Braided Sutures, Sterile Acetic Acid, see Acetic Acid (33 per cent) Acidified Methanol, A78 Synthetic, 3453 Acetic Anhydride, A18 Acidified Methylene Chloride, see Absorbable Monofilament Sutures, Acetic Anhydride Solution R1, A18 Acidified Dichloromethane Sterile Synthetic, 3455 Acetic Anhydride–Dioxan Solution, A18 Acid-insoluble Ash, Determination of, Absorbent Cotton, 3449 Acetic Anhydride–Sulphuric Acid A291 Absorbent Viscose Wadding, 3450 Solution, A18 Acid-washed Diatomaceous Support, Absorption spectrophotometry, infrared, Acetic Bromine Solution, A32 A47 A149 Acetone, 55, A18 Acitretin, 66 Absorption Spectrophotometry, Acetone, Deuterated, A46 Acknowledgements, xxiii Ultraviolet and Visible, A155 Acetone Solution, Buffered, A141 Acrylamide, A19 Acacia, 39, A17 Acetone-dried Ox Brain, A90 Acrylamide/bisacrylamide (29:1) Acacia Solution, A17 Acetonitrile, A18 Solution, 30 per cent, A19 Acacia, Spray-dried, 40 Acetonitrile for Chromatography, A18 Acrylamide/bisacrylamide (36.5:1) Acamprosate Calcium, 41 Acetonitrile R1, A18 Solution, 30 per cent, A19 Acarbose, 42 Acetoxyvalerenic Acid, A18 Acrylic Acid, A19 Acarbose, Chromatogram, A645 Acetyl Chloride, A18 Acteoside, A19 Accuracy, A587 Acetyl groups (O) in Polysaccharide Action and Use Statement, Status of, 16, Acebutolol Capsules, 2335 Vaccines, A398 1188, 2268, 3810 Acebutolol Hydrochloride, 44, S4, A17 Acetyl Groups, Reactions of, A239 Activated Acid Aluminium Oxide, A21 Acebutolol Tablets, 2335 Acetyl Value, Determination of, Activated Attapulgite, 196 Aceclofenac, 46 A275-287 Activated Charcoal, 454, A37 Acemetacin, 48 Acetylacetamide, A18 Activated coagulation factors, A365 Acenocoumarol, 50,S5 Acetylacetone, A18 Activated protein C chromogenic Acenocoumarol Tablets, 2336 Acetylacetone Reagent R1, A18 substrate, A370 Acesulfame Potassium, 51 4-Acetylbiphenyl, A18 Activated Zinc, A129 Acetal, A17 N-Acetyl-e-caprolactam, A18 Active Moiety, A564 Acetaldehyde, A17 Acetylcholine Chloride, 56, A18 Active Substances, 37, 1209, see also Acetaldehyde Ammonia Trimer Acetylcysteine, 57,S6 Substances for Pharmaceutical Use Trihydrate, A17 Acetylcysteine Injection, 2337 Additions, List of, xxiv Acetaldehyde Standard Solution Acetyldigoxin, 59 Additions, List of Monographs, xx (100 ppm C2H4O), A136 b-Acetyldigoxin, Chromatogram, A646 Additives, Plastic, A513 Acetaldehyde Standard Solution b-Acetyldigoxin, see Acetyldigoxin Adenine, 67, A19 (100 ppm C2H4O) R1, A136 Acetyleugenol, A18 Adenosine, 68, A19 Acetamide, A17 N-Acetylglucosamine, A18 Adenovirus Vectors for Human Use, Acetaminophen, see Paracetamol Acetyl-11-keto-b-boswellic Acid, A18 A747 Acetate Buffer pH 2.8, A141 N-Acetyl-L-cysteine, A18 Adipic Acid, 70, A19 Acetate Buffer pH 2.45, A140 N-Acetylneuraminic Acid, A19 Adrenaline, 71, A19 Acetate Buffer pH 3.4, A141 Acetylsalicylic Acid Tablets, see Aspirin Adrenaline Acid Tartrate, 72, A19 Acetate Buffer pH 3.5, A141 Tablets Adrenaline and Cocaine Intranasal Acetate Buffer pH 3.7, A141 Acetylsalicylic Acid, see Aspirin Solution, 2345 Acetate Buffer pH 4.4, A141 N-Acetyltryptophan, 61, A19 Adrenaline (Epinephrine), S6 Acetate Buffer pH 4.6, A141 N-Acetyltryptophan, see Acetyltryptophan Adrenaline Eye Drops, Acetate Buffer pH 5.0, A141 Acetyltyrosine, 63 Neutral/Epinephrine Eye Drops, Acetate Buffer pH 6.0, A141 Acetyltyrosine Ethyl Ester, A19 Neutral, 2342 Acetate Buffer Solution pH 4.4, see Acetyltyrosine Ethyl Ester, 0.2M, A19 Adrenaline Eye Drops/Epinephrine Eye Acetate Buffer pH 4.4 N-Acetyltyrosine, see Acetyltyrosine Drops, 2342 Acetate buffer solution pH 4.6, see Aciclovir, 64 Adrenaline Injection, Bupivacaine and, Acetate Buffer pH 4.6 Aciclovir Cream, 2338 2437 Acetate Buffer Solution pH 6.0, see Aciclovir Eye Ointment, 2339 Adrenaline Injection, Dilute (1 in Acetate Buffer pH 6.0 Aciclovir Intravenous Infusion, 2339 10,000), 2344 Acetate Buffer Solution pH 4.5, A141 Aciclovir Oral Suspension, 2340 Adrenaline Injection, Lidocaine and, Acetate Buffer Solution pH 4.7, A141 Aciclovir Sodium for Intravenous 2843 Acetate Buffer Solution pH 5.0, A141 Infusion, 2339 A772 Index Adrenaline Injection/Epinephrine Agarose for Chromatography R1, Cross- Aldehydes, Determination of, A279 Injection, 2343 linked, A20 Aldrin, A20 Adrenaline Solution/Epinephrine Agarose for Electrophoresis, A20 Aleuritic Acid, A20 Solution, 2344 Agarose/Cross-linked Polyacrylamide, Alexandrian Senna Fruit, 3721 Adrenaline Tartrate A20 Alexandrian Senna Pods, see Alexandrian Injection/Epinephrine Tartrate Agarose-DEAE for Ion Exchange Senna Fruit Injection, 2343 Chromatography, A20 Alfacalcidol, 81 Adrenaline Tartrate Agglomerate, A450 Alfadex, 82 Solution/Epinephrine Tartrate Aggregate, A450 Alfentanil Hydrochloride, 84 Solution, 2344 Agnus Castus Fruit, 3468 Alfuzosin Hydrochloride, 85 Adrenaline Tartrate, see Adrenaline Acid Agrimony, 3470 Alginate Antacid Oral Suspension, Tartrate Air, Medical, 74 Compound, 2347 Adrenalone Hydrochloride, A19 Air Permeability, Specific Surface Area Alginate Oral Suspension, Raft-forming, Adsorbed Diphtheria and Tetanus by, A433 2348 Vaccine for Adults and Adolescents, Air, Synthetic, 76 Alginate Raft-forming Oral Suspension, see Diphtheria and Tetanus Vaccine Air, Synthetic Medicinal, see Synthetic Air 2348 (Adsorbed, Reduced Antigen(s) Content) Airtight Container, A471 Alginic Acid, 87 Adsorbed Diphtheria and Tetanus Airtight container, Definition of, 27, Alimemazine, S7 Vaccine, see Diptheria and Tetanus 1199, 2279, 3822 Alimemazine Oral Solution, Paediatric, Vaccine, Adsorbed Alanine, 77, A20 2348 Adsorbed Diphtheria, Tetanus and ß-Alanine, see 3-Aminopropionic Acid Alimemazine Tablets, 2349 Pertussis (Acellular Component) Albendazole, 78 Alimemazine Tartrate, 88 Vaccine, see Diphtheria, Tetanus and Albendazole Oral Suspension, Spectrum, Alizarin S, A20 Pertussis (Acellular Component) Vaccine, A710 Alizarin S Solution, A20 (Adsorbed) Albendazole Oral Suspension with Alkaline Corallin Solution, A43 Adsorbed Diphtheria, Tetanus and Minerals, Spectrum, A710 Alkaline Eye Drops, see Hypromellose Eye Pertussis Vaccine, 3258 Albumin, Bovine, A20 Drops Adsorbed Diphtheria, Tetanus, Pertussis Albumin, Human, A20 Alkaline Gentian Mixture, 3586 (Acellular Component) and Albumin Injection, Iodinated [125I], 3378 Alkaline Gentian Oral Solution, 3586 Haemophilus Type b Conjugate Albumin Solution, 3197 Alkaline Hydroxylamine Solution, A68 Vaccine, see Diphtheria, Tetanus, Albumin Solution, Human, A20 Alkaline Hydroxylamine Solution R1, Pertussis (Acellular Component) and Albumin Solution R1, Human, A20 A68 Haemophilus Type b Conjugate Vaccine, Albumin, see Albumin Solution Alkaline Impurities, Fixed Oils, A280 (Adsorbed) Alchemilla, 3471 Alkaline Potassium Mercuri-iodide Adsorbed Diphtheria, Tetanus, Pertussis Alcohol (20 per cent), 830 Solution, A100 (Acellular Component) and Hepatitis Alcohol (25 per cent), 830 Alkaline Potassium Tetraiodomercurate B (rDNA) Vaccine, see Diphtheria, Alcohol (45 per cent), 830 Solution, A101 Tetanus, Pertussis (Acellular Component) Alcohol (50 per cent), 830 Alkaline Pyrogallol Solution, A103 and Hepatitis B (rDNA) Vaccine, Alcohol (60 per cent), 830 Alkaline Sodium Picrate Solution, A114 (Adsorbed) Alcohol (70 per cent), 830 Alkaline Tetrazolium Blue Solution, Adsorbed Diphtheria, Tetanus, Pertussis Alcohol (80 per cent), 830 A120 (Acellular Component) and Alcohol (90 per cent), 830 Alkali-washed Diatomaceous Support, Inactivated Poliomyelitis Vaccine, see Alcohol, Aldehyde-free, see Ethanol A47 Diphtheria, Tetanus, Pertussis (Acellular (96%), Aldehyde-free Alkaloids, Complete Extraction of, A290 Component) and Poliomyelitis Alcohol, see Ethanol (96%) Alkaloids, Reactions of, A239 (Inactivated) Vaccine, (Adsorbed) Alcoholic Calcium Standard Solution
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    Epinephrine versus tramazoline to reduce nasal bleeding during nasotracheal intubation. A double- blind randomized trial Aiji Sato(Boku) ( [email protected] ) Aichi Gakuin University Yoshiki Sento Nagoya City University Yuji Kamimura Nagoya City University Eisuke Kako Nagoya City University Masahiro Okuda Aichi Gakuin University Naoko Tachi Aichi Gakuin University Yoko Okumura Aichi Gakuin University Mayumi Hashimoto Aichi Gakuin University Hiroshi Hoshijima Tohoku University Fumihito Suzuki Akita National Hospital Kazuya Sobue Nagoya City University Research Article Keywords: Nasotracheal intubation, Epinephrine, Tramazoline, Nasal bleeding Posted Date: February 10th, 2021 DOI: https://doi.org/10.21203/rs.3.rs-148779/v1 Page 1/14 License: This work is licensed under a Creative Commons Attribution 4.0 International License. Read Full License Page 2/14 Abstract BACKGROUND Nasal bleeding is the most common complication during nasotracheal intubation (NTI). To reduce nasal bleeding, the nasal cavity is treated with vasoconstrictors (epinephrine [E] or tramazoline [T]) prior to NTI. This study aimed to determine whether E or T is more effective and safe for reducing nasal bleeding during NTI. METHODS This study was preregistered on UMIN-CTR after being approved by the IRB of the School of Dentistry at Aichi Gakuin University. Written consent was received from all the patients. Total 206 patients aged 20–70 years and classied as 1–2 on American Society of Anesthesiologists-physical status were scheduled to undergo general anesthesia with NTI. Patients with a narrowed nasal cavity observed during preoperative CT test (n = 3), patients with hypertension (n = 3), patients undergoing antithrombotic therapy, and patients who did not give consent (n = 3) were excluded from the study.
  • List of Union Reference Dates A

    List of Union Reference Dates A

    Active substance name (INN) EU DLP BfArM / BAH DLP yearly PSUR 6-month-PSUR yearly PSUR bis DLP (List of Union PSUR Submission Reference Dates and Frequency (List of Union Frequency of Reference Dates and submission of Periodic Frequency of submission of Safety Update Reports, Periodic Safety Update 30 Nov. 2012) Reports, 30 Nov.
  • Application and Review of Pediatric Pharmacotherapy, Sample Chapter

    Application and Review of Pediatric Pharmacotherapy, Sample Chapter

    Application and Review of Pediatric Pharmacotherapy Chapter No. 1 Dated: 29/7/2010 At Time: 16:16:4 Section 1 Neonatal intensive care “Luck is where preparation meets opportunity.” This section consists of 16 medication orders followed by corresponding patient profiles representing pharmacotherapy associated with patients admit- ted to a neonatal intensive care unit. Each patient profile is followed by multiple-choice questions pertaining to the medication order and profile infor- mation. Choose the one best-lettered response to each item. The correct answers are provided at the end of this section. The reader is encouraged to attempt all questions for each case or for the entire section prior to referring to the answers. Moreover, where appropriate, the answer key provides a thor- ough explanation of the correct response and should serve as an additional learning tool for the reader. Application and Review of Pediatric Pharmacotherapy Chapter No. 1 Dated: 29/7/2010 At Time: 16:16:4 2 | Application and Review of Pediatric Pharmacotherapy Medication orders Physician order Patient weight: 2.5 kg Aminophylline 10 mg iv load, then begin 2.5 mg iv q 12 h Obtain theophylline concentration 1 h postinfusion of loading dose Date/time: 12/01/2100 Patient name: Baby Boy Turner Physician: John Craver Patient ID: 111222 Medical profile Patient: Baby Boy Turner Patient weight: 2.5 kg Age: 1d/o Present illness: Apneic episodes Allergies: None Medical history: 33 weeks gestation, Apgar 7 and 9 Labs: pending Medication profile Questions Q1 Which of the following is an acceptable definition of apnea of prematurity? 1 o cessation of breathing for less than 20 s 2 o cessation of breathing for at least 20 s 3 o cessation of breathing for less than 20 s when accompanied by bradycardia A o 1 only B o 3 only C o 1 and 3 only Application and Review of Pediatric Pharmacotherapy Chapter No.
  • Caffeine in the Treatment of Pain

    Caffeine in the Treatment of Pain

    Rev Bras Anestesiol ARTIGOS DE REVISÃO 2012; 62: 3: 387-401 ARTIGOS DE REVISÃO Cafeína para o Tratamento de Dor Cristiane Tavares, TSA 1, Rioko Kimiko Sakata, TSA 2 Resumo: Tavares C, Sakata RK – Cafeína para o Tratamento de Dor. Justificativa e objetivos: A cafeína é uma substância amplamente consumida com efeitos em diversos sistemas e que apresenta farmacoci- nética e farmacodinâmica características, causando interações com diversos medicamentos. O objetivo deste estudo é fazer uma revisão sobre os efeitos da cafeína. Conteúdo: Nesta revisão, são abordados a farmacologia da cafeína, os mecanismos de ação, as indicações, as contraindicações, as doses, as interações e os efeitos adversos. Conclusões: Faltam estudos controlados, randomizados e duplos-cegos para avaliar a eficácia analgésica da cafeína nas diversas síndromes dolorosas. Em pacientes com dor crônica, é necessário ter cautela em relação ao desenvolvimento de tolerância, abstinência e interação medi- camentosa no uso crônico de cafeína. Unitermos: ANALGESIA; DOR; DROGAS, Alcaloide/cafeína. ©2012 Elsevier Editora Ltda. Todos os direitos reservados. INTRODUÇÃO Estrutura química A cafeína foi isolada em 1820, mas a estrutura correta des- A cafeína é um alcaloide presente em mais de 60 espécies ta metilxantina foi estabelecida na última década do século de plantas 4. Sua estrutura molecular pertence a um grupo XIX. Os efeitos não foram claramente reconhecidos até 1981, de xantinas trimetiladas que incluem seus compostos inti- quando o bloqueio de receptores adenosina foi correlacio- mamente relacionados: teobromina (presente no cacau) e nado às propriedades estimulantes da cafeína e de seus teofilina (presente no chá) 1. Quimicamente, esses alcaloides análogos 1. Provavelmente a cafeína é uma das substâncias são semelhantes a purinas, xantinas e ácido úrico, que são psicoativas mais utilizadas no mundo, promovendo efeitos compostos metabolicamente importantes 4.