MATERIAL SAFETY DATA SHEET Diisobutylaluminium hydride, 1.0M solution in heptane
Section 1 Chemical Product and Company Identification
MSDS Name: Diisobutylaluminium hydride, 1.0M solution in heptane Catalog Numbers: 201050000, 201051000, 201058000 Synonyms: DIBALH, 1.0M solution in heptane Company Identification: Acros Organics BVBA Janssen Pharmaceuticalaan 3a 2440 Geel, Belgium Company Identification: (USA) Acros Organics One Reagent Lane Fair Lawn, NJ 07410 For information in the US, call: 800ACROS01 For information in Europe, call: +32 14 57 52 11 Emergency Number, Europe: +32 14 57 52 99 Emergency Number US: 2017967100 CHEMTREC Phone Number, US: 8004249300 CHEMTREC Phone Number, Europe: 7035273887
Section 2 Composition, Information on Ingredients
CAS# Chemical Name: % EINECS# Hazard Symbols: Risk Phrases: 142825 Heptane (n) 80 2055638 F N XN 11 38 50/53 65 67 1191157 Diisobutylaluminum hydride 20 2147299 F C 14/15 17 35 Text for Rphrases: see Section 16 Hazard Symbols: F C N
Risk Phrases: 11 14/15 35 50/53 65 67
Section 3 Hazards Identification
EMERGENCY OVERVIEW Highly flammable. Reacts violently with water liberating extremely flammable gases. Causes severe burns. Very toxic to aquatic organisms, may cause longterm adverse effects in the aquatic environment. Harmful: may cause lung damage if swallowed. Vapours may cause drowsiness and dizziness. Potential Health Effects Eye: Causes eye burns. Skin: Causes skin burns. Ingestion: Causes gastrointestinal tract burns. May cause lung damage. Inhalation: Causes chemical burns to the respiratory tract. Chronic:
Section 4 First Aid Measures
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Skin: Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Do not induce vomiting. Get medical aid immediately. Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Notes to Treat symptomatically and supportively. Physician:
Section 5 Fire Fighting Measures
General As in any fire, wear a selfcontained breathing apparatus in pressuredemand, Information: MSHA/NIOSH (approved or equivalent), and full protective gear. Will burn if involved in a fire. Water Reactive. Material will react with water and may release a flammable and/or toxic gas. Flammable liquid and vapor. Extinguishing Use dry sand or earth to smother fire. DO NOT USE WATER! Use dry chemical. Media:
Section 6 Accidental Release Measures
General Use proper personal protective equipment as indicated in Section 8. Information: Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Remove all sources of ignition. Use a sparkproof tool. Do not expose spill to water.
Section 7 Handling and Storage
Handling: Do not allow water to get into the container because of violent reaction. Use sparkproof tools and explosion proof equipment. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Do not allow contact with water. Use only in a chemical fume hood. Storage: Keep away from sources of ignition. Store in a cool, dry place. Store in a tightly closed container. Flammablesarea. Corrosives area. Water free area. Store under nitrogen.
Section 8 Exposure Controls, Personal Protection
Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local explosionproof ventilation to keep airborne levels to acceptable levels. Exposure Limits CAS# 142825: United Kingdom, WEL TWA: 500 ppm TWA United Kingdom, WEL STEL: 1500 ppm STEL United States OSHA: 500 ppm TWA; 2000 mg/m3 TWA Belgium TWA: 400 ppm VLE; 1664 mg/m3 VLE Belgium STEL: 500 ppm VLE; 2085 mg/m3 VLE France VME: 500 ppm VME; 2085 mg/m3 VME Germany: 500 ppm TWA; 2100 mg/m3 TWA Japan: 200 ppm OEL; 820 mg/m3 OEL Malaysia: 400 ppm TWA; 1640 mg/m3 TWA Netherlands: 400 ppm STEL; 1600 mg/m3 STEL Netherlands: 300 ppm MAC; 1200 mg/m3 MAC Spain: 500 ppm VLAED; 2085 mg/m3 VLAED CAS# 1191157:
Personal Protective Equipment Eyes: Wear chemical splash goggles. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Section 9 Physical and Chemical Properties
Physical State: Clear liquid Color: colorless Odor: solvent odor pH: 7 Vapor Pressure: Not available Viscosity: Not available Boiling Point: Not available Freezing/Melting Point: 70 deg C ( 94.00°F) Autoignition Temperature: Not available Flash Point: 1 deg C ( 30.20 deg F) Explosion Limits: Lower: Not available Explosion Limits: Upper: Not available Decomposition Temperature: Solubility in water: vigorous reaction Specific Gravity/Density: 0.700 Molecular Formula: C8H19Al Molecular Weight: 142.22
Section 10 Stability and Reactivity
Chemical Stability: Air sensitive. Reacts violently with water. Moisture sensitive. Conditions to Avoid: Incompatible materials, ignition sources, exposure to air, exposure to moist air or water, evaporating to near dryness, allowing solvents to evaporate, temperatures above 120°C. Incompatibilities with Water, acidic conditions, strong oxidizing agents, acids, alcohols, oxygen, Other Materials organic halides. Hazardous Carbon monoxide, carbon dioxide, aluminum oxide, aluminum fumes. Decomposition Products Hazardous Has not been reported. Polymerization
Section 11 Toxicological Information
RTECS#: CAS# 142825: MI7700000 CAS# 1191157: BD0710000 LD50/LC50: RTECS: CAS# 142825: Inhalation, rat: LC50 = 103 gm/m3/4H; . RTECS: CAS# 1191157:. Carcinogenicity: Heptane (n) Not listed as a carcinogen by ACGIH, IARC, NTP, or CA Prop 65. Diisobutylaluminum hydride Not listed as a carcinogen by ACGIH, IARC, NTP, or CA Prop 65. Other: The toxicological properties have not been fully investigated. See actual entry in RTECS for complete information.
Section 12 Ecological Information
Other: Harmful to aquatic life in very low concentrations.
Section 13 Disposal Considerations
Dispose of in a manner consistent with federal, state, and local regulations. Section 14 Transport Information
IATA IMO RID/ADR ORGANOMETALLIC SUBSTANCE, LIQUID, ORGANOMETALLIC ORGANOMETALLIC Shipping WATER SUBSTANCE, LIQUID, SUBSTANCE, LIQUID, Name: REACTIVE,FLAMMABLE* WATER WATER (forbidden to ship via REACTIVE,FLAMMABLE REACTIVE,FLAMMABLE passenger air) Hazard 4.3 (3) 4.3 (3) 4.3 (3) Class: UN 3399 3399 3399 Number: Packing I I I Group:
Section 15 Regulatory Information
European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: F C N Risk Phrases: R 11 Highly flammable. R 14/15 Reacts violently with water liberating extremely flammable gases. R 35 Causes severe burns. R 50/53 Very toxic to aquatic organisms, may cause long term adverse effects in the aquatic environment. R 65 Harmful: may cause lung damage if swallowed. R 67 Vapours may cause drowsiness and dizziness. Safety Phrases: S 6A Keep under nitrogen. S 16 Keep away from sources of ignition No smoking. S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 Wear suitable protective clothing, gloves and eye/face protection. S 43A In case of fire, use dry chemical (never use water). S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). WGK (Water Danger/Protection) CAS# 142825: 1 CAS# 1191157: 2 Canada CAS# 142825 is listed on Canada's DSL List CAS# 1191157 is listed on Canada's DSL List US Federal TSCA CAS# 142825 is listed on the TSCA Inventory. CAS# 1191157 is listed on the TSCA Inventory.
Section 16 Other Information
Text for Rphrases from Section 2 R 11 Highly flammable. R 14/15 Reacts violently with water liberating extremely flammable gases. R 17 Spontaneously flammable in air. R 35 Causes severe burns. R 38 Irritating to skin. R 50/53 Very toxic to aquatic organisms, may cause long term adverse effects in the aquatic environment. R 65 Harmful: may cause lung damage if swallowed. R 67 Vapours may cause drowsiness and dizziness. MSDS Creation Date: 3/09/2004 Revision #1 Date 1/04/2005 Revisions were made in Sections: General revision.
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