ABIM Pulmonary Disease Certification Exam Blueprint
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A Comparative Study of Pneumomediastinums Based on Clinical Experience
ORIGINAL ARTICLE A comparative study of pneumomediastinums based on clinical experience Ersin Sapmaz, M.D.,1 Hakan Işık, M.D.,1 Deniz Doğan, M.D.,2 Kuthan Kavaklı, M.D.,1 Hasan Çaylak, M.D.1 1Department of Thoracic Surgery, Gülhane Training and Research Hospital, Ankara-Turkey 2Department of Pulmonology, Gülhane Training and Research Hospital, Ankara-Turkey ABSTRACT BACKGROUND: Pneumomediastinum (PM) is the term which defines the presence of air in the mediastinum. PM has also been described as mediastinal emphysema. PM is divided into two subgroups called as Spontaneous PM (SPM) and Secondary PM (ScPM). METHODS: A retrospective comparative study of the PM diagnosed between February 2010 and July 2018 is presented. Forty patients were compared. Clinical data on patient history, physical characteristics, symptoms, findings of examinations, length of the hospital stay, treatments, clinical time course, recurrence and complications were investigated carefully. Patients with SPM, Traumatic PM (TPM) and Iatrogenic PM (IPM) were compared. RESULTS: SPM was identified in 14 patients (35%). In ScPM group, TPM was identified in 16 patients (40%), and IPM was identified in 10 patients (25%). On the SPM group, the most frequently reported symptoms were chest pain, dyspnea, subcutaneous emphysema and cough. CT was performed to all patients to confirm the diagnosis and to assess the possible findings. All patients prescribed pro- phylactic antibiotics to prevent mediastinitis. CONCLUSION: The present study aimed to evaluate the clinical differences and managements of PMs in trauma and non-trauma patients. The clinical spectrum of pneumomediastinum may vary from benign mediastinal emphysema to a fatal mediastinitis due to perforation of mediastinal structures. -
Pulmonary Microscopic Polyangiitis Presenting As Acute Respiratory Failure from Diffuse Alveolar Hemorrhage
Case report SARCOIDOSIS VASCULITIS AND DIFFUSE LUNG DISEASES 2015; 32; 372-377 © Mattioli 1885 Pulmonary microscopic polyangiitis presenting as acute respiratory failure from diffuse alveolar hemorrhage Katharine K. Roberts1, Michael M. Chamberlin2, Allen R. Holmes3, Jonathan L. Henderson4, Robert L. Hutton3, William N. Hannah1, Michael J. Morris4 1 Internal Medicine Residency, Department of Medicine, San Antonio Military Medical Center; 2 Internal Medicine, United States Army Health Clinic, Vilseck, Germany; 3 Pathology Residency, Department of Pathology, San Antonio Military Medical Center; 4 Pulmonary/ Critical Care Service, Department of Medicine, San Antonio Military Medical Center Abstract. MicrMicroscopicoscopic polyangiitis and granulomatosis with polyangiitis are rare anti-neutrophilic cytoplas-cytoplas- mic antibody-associated systemic vasculitides that predominantly affect small to medium sized vessels of the lungs and kidneys. These syndromes are largely confined to older adults and often present sub-acutely follow- ing weeks to months of nonspecific prodromal symptoms. While both diseases often manifest within multiple organ systems concurrently, the disease spectrum of microscopic polyangiitis almost always includes the kidneys, while granulomatosis with polyangiitis is most commonly associated with pulmonary disease. We present two cases of rapid onset respiratory failure secondary to diffuse alveolar hemorrhage in young active duty military personnel. After serological testing and surgical lung biopsy, both patients were -
Tuberculosis Mediastinal Fibrosis Misdiagnosed As Chronic Bronchitis for 10 Years: a Case Report
1183 Letter to the Editor Tuberculosis mediastinal fibrosis misdiagnosed as chronic bronchitis for 10 years: a case report Wei-Wei Gao, Xia Zhang, Zhi-Hao Fu,Wei-Yi Hu, Xiang-Rong Zhang, Guang-Chuan Dai, Yi Zeng Department of Tuberculosis of Three, Nanjing Public Health Medical Center, Nanjing Second Hospital, Nanjing Hospital Affiliated to Nanjing University of Traditional Chinese Medicine, Nanjing 211132, China Correspondence to: Dr. Yi Zeng. Department of Tuberculosis of Three, Nanjing Public Health Medical Center, Nanjing Second Hospital, Nanjing Hospital Affiliated to Nanjing University of Traditional Chinese Medicine, No. 1, Kangfu Road, Nanjing 211132, China. Email: [email protected]. Submitted Feb 27, 2019. Accepted for publication Jun 19, 2019. doi: 10.21037/qims.2019.06.13 View this article at: http://dx.doi.org/10.21037/qims.2019.06.13 Background over previous 2 months. All vital signs at presentation were normal (temperature: 37.6 , heart rate: 97/min, blood Mediastinal fibrosis (MF, or fibrosing mediastinitis) is a rare pressure: 155/95 mmHg, saturation: 95%). Clinical physical condition characterized by rapid increase of fibrous tissues in ℃ examination revealed a lip purpura and reduced breath the mediastinum and is often associated with granulomatous sound in the right lung. diseases such as histoplasmosis, tuberculosis, sarcoidosis, and other fibroinflammatory and autoimmune diseases (1-3). It can cause compression and obliteration of vital mediastinal Laboratory tests structures, e.g., trachea, esophagus, and great vessels (4,5). Blood test results were as follows: blood cell count and Given that the disease is rare and its clinical symptoms liver and kidney function normal. -
Mediastinitis and Bilateral Pleural Empyema Caused by an Odontogenic Infection
Radiol Oncol 2007; 41(2): 57-62. doi:10.2478/v10019-007-0010-0 case report Mediastinitis and bilateral pleural empyema caused by an odontogenic infection Mirna Juretic1, Margita Belusic-Gobic1, Melita Kukuljan3, Robert Cerovic1, Vesna Golubovic2, David Gobic4 1Clinic for Oral and Maxillofacial Surgery, 2Clinic for Anaesthesiology and Reanimatology, 3Department of Radiology, 4Clinic for Internal Medicine, Clinical hospital, Rijeka, Croatia Background. Although odontogenic infections are relatively frequent in the general population, intrathoracic dissemination is a rare complication. Acute purulent mediastinitis, known as descending necrotizing mediastin- itis (DNM), causes high mortality rate, even up to 40%, despite high efficacy of antibiotic therapy and surgical interventions. In rare cases, unilateral or bilateral pleural empyema develops as a complication of DNM. Case report. This case report presents the treatment of a young, previously healthy patient with medias- tinitis and bilateral pleural empyema caused by an odontogenic infection. After a neck and pharynx re-inci- sion, and as CT confirmed propagation of the abscess to the thorax, thoracotomy was performed followed by CT-controlled thoracic drainage with continued antibiotic therapy. The patient was cured, although the recognition of these complications was relatively delayed. Conclusions. Early diagnosis of DNM can save the patient, so if this severe complication is suspected, thoracic CT should be performed. Key words: mediastinitis; empyema, pleural; periapical abscess – complications Introduction rare complication of acute mediastinitis.1-6 Clinical manifestations of mediastinitis are Acute suppurative mediastinitis is a life- frequently nonspecific. If the diagnosis of threatening infection infrequently occur- mediastinitis is suspected, thoracic CT is ring as a result of the propagation of required regardless of negative chest X-ray. -
Asphyxia Neonatorum
CLINICAL REVIEW Asphyxia Neonatorum Raul C. Banagale, MD, and Steven M. Donn, MD Ann Arbor, Michigan Various biochemical and structural changes affecting the newborn’s well being develop as a result of perinatal asphyxia. Central nervous system ab normalities are frequent complications with high mortality and morbidity. Cardiac compromise may lead to dysrhythmias and cardiogenic shock. Coagulopathy in the form of disseminated intravascular coagulation or mas sive pulmonary hemorrhage are potentially lethal complications. Necrotizing enterocolitis, acute renal failure, and endocrine problems affecting fluid elec trolyte balance are likely to occur. Even the adrenal glands and pancreas are vulnerable to perinatal oxygen deprivation. The best form of management appears to be anticipation, early identification, and prevention of potential obstetrical-neonatal problems. Every effort should be made to carry out ef fective resuscitation measures on the depressed infant at the time of delivery. erinatal asphyxia produces a wide diversity of in molecules brought into the alveoli inadequately com Pjury in the newborn. Severe birth asphyxia, evi pensate for the uptake by the blood, causing decreases denced by Apgar scores of three or less at one minute, in alveolar oxygen pressure (P02), arterial P02 (Pa02) develops not only in the preterm but also in the term and arterial oxygen saturation. Correspondingly, arte and post-term infant. The knowledge encompassing rial carbon dioxide pressure (PaC02) rises because the the causes, detection, diagnosis, and management of insufficient ventilation cannot expel the volume of the clinical entities resulting from perinatal oxygen carbon dioxide that is added to the alveoli by the pul deprivation has been further enriched by investigators monary capillary blood. -
Acute (Serious) Bronchitis
Acute (serious) Bronchitis This is an infection of the air tubes that go down to your lungs. It often follows a cold or the flu. Most people do not need treatment for this. The infection normally goes away in 7-10 days. We make every effort to make sure the information is correct (right). However, we cannot be responsible for any actions as a result of using this information. Getting Acute Bronchitis How the lungs work Your lungs are like two large sponges filled with tubes. As you breathe in, you suck oxygen through your nose and mouth into a tube in your neck. Bacteria and viruses in the air can travel into your lungs. Normally, this does not cause a problem as your body kills the bacteria, or viruses. However, sometimes infection can get through. If you smoke or if you have had another illness, infections are more likely to get through. Acute Bronchitis Acute bronchitis is when the large airways (breathing tubes) to the lungs get inflamed (swollen and sore). The infection makes the airways swell and you get a build up of phlegm (thick mucus). Coughing is a way of getting the phlegm out of your airways. The cough can sometimes last for up to 3 weeks. Acute Bronchitis usually goes away on its own and does not need treatment. We make every effort to make sure the information is correct (right). However, we cannot be responsible for any actions as a result of using this information. Symptoms (feelings that show you may have the illness) Symptoms of Acute Bronchitis include: • A chesty cough • Coughing up mucus, which is usually yellow, or green • Breathlessness when doing more energetic activities • Wheeziness • Dry mouth • High temperature • Headache • Loss of appetite The cough usually lasts between 7-10 days. -
Evaluation of Metal and Noise Exposures at an Aircraft Powerplant Parts Manufacturer
Evaluation of Metal and Noise Exposures at an Aircraft Powerplant Parts Manufacturer HHE Report No. 2018-0001-3349 April 2019 Authors: Karl D. Feldmann, MS, CIH David A. Jackson, MD Analytical Support: Jennifer Roberts, Maxxam Analytics Desktop Publisher: Jennifer Tyrawski Editor: Cheryl Hamilton Industrial Hygiene Field Assistance: Scott Brueck, Jessica Li, Kevin Moore Logistics: Donnie Booher, Kevin Moore, Mihir Patel Medical Field Assistance: Deborah Sammons, Miriam Siegel Statistical Support: Miriam Siegel Keywords: North American Industry Classification System (NAICS) Code 336412 (Aircraft Engine and Engine Parts Manufacturing), Oregon, Welding, Tungsten Inert Gas, TIG Welding, Inconel, Stainless Steel, Chromium, Hexavalent Chromium, Hex Chrome, Chrome Six, Chrome 6, Chrome IV, Crvi, Cr(VI), Nickel, Cobalt, Biomonitoring, BEI, Noise Disclaimer The Health Hazard Evaluation Program investigates possible health hazards in the workplace under the authority of the Occupational Safety and Health Act of 1970 [29 USC 669a(6)]. The Health Hazard Evaluation Program also provides, upon request, technical assistance to federal, state, and local agencies to investigate occupational health hazards and to prevent occupational disease or injury. Regulations guiding the Program can be found in Title 42, Code of Federal Regulations, Part 85; Requests for Health Hazard Evaluations [42 CFR Part 85]. Availability of Report Copies of this report have been sent to the employer and employee representative at the facility. The state and local health department and the Occupational Safety and Health Administration Regional Office have also received a copy. This report is not copyrighted and may be freely reproduced. Recommended Citation NIOSH [2019]. Evaluation of metal and noise exposures at an aircraft powerplant parts manufacturer. -
Octreotide Treatment of Idiopathic Pulmonary Fibrosis: a Proof-Of-Concept Study
drugs, while two patients underwent surgery in addition to Roncaccio 16, 21049, Tradate, Italy. E-mail: giovannibattista. chemotherapy. [email protected] As in other reference centres, the E. Morelli Hospital needs to transfer out all admitted cases to the hospitals referring them for Support Statement: This study was supported by the current specialised treatment, when culture conversion and clinical research funds of the participating institutions. For this stability have been achieved. Patients were transferred out after publication, the research leading to these results has received a median (IQR) hospital stay of 75.5 (51.5–127.5) days; 12 (100%) funding from the European Community’s Seventh Framework out of 12 and nine (75%) out of 12 achieved sputum-smear and Programme (FP7/2007-2013) under grant agreement FP7- culture conversion, after a median (IQR) time of 40.5 (24–64) and 223681. 70 (44–95) days, respectively. As of June 2011, one patient was cured, two had died and nine were still under treatment. Statement of Interest: None declared. Four (33.3%) cases reported adverse events, two being major (16.7%; neuropathy and low platelet count, needing temporary REFERENCES interruption of linezolid) and two minor (neuropathy and mild 1 Villar M, Sotgiu G, D’Ambrosio L, et al. Linezolid safety, anaemia). All adverse events were reversible. tolerability and efficacy to treat multidrug- and extensively drug-resistant tuberculosis. Eur Respir J 2011; 38: 730–733. In conclusion, despite the intrinsic difficulty of evaluating the 2 World Health Organization. Multidrug and extensively drug safety and tolerability of linezolid (administered within different resistant TB (M/XDR-TB): 2010 global report on surveillance and regimens including multiple anti-TB drugs guided by drug response. -
Respiratory and Gastrointestinal Involvement in Birth Asphyxia
Academic Journal of Pediatrics & Neonatology ISSN 2474-7521 Research Article Acad J Ped Neonatol Volume 6 Issue 4 - May 2018 Copyright © All rights are reserved by Dr Rohit Vohra DOI: 10.19080/AJPN.2018.06.555751 Respiratory and Gastrointestinal Involvement in Birth Asphyxia Rohit Vohra1*, Vivek Singh2, Minakshi Bansal3 and Divyank Pathak4 1Senior resident, Sir Ganga Ram Hospital, India 2Junior Resident, Pravara Institute of Medical Sciences, India 3Fellow pediatrichematology, Sir Ganga Ram Hospital, India 4Resident, Pravara Institute of Medical Sciences, India Submission: December 01, 2017; Published: May 14, 2018 *Corresponding author: Dr Rohit Vohra, Senior resident, Sir Ganga Ram Hospital, 22/2A Tilaknagar, New Delhi-110018, India, Tel: 9717995787; Email: Abstract Background: The healthy fetus or newborn is equipped with a range of adaptive, strategies to reduce overall oxygen consumption and protect vital organs such as the heart and brain during asphyxia. Acute injury occurs when the severity of asphyxia exceeds the capacity of the system to maintain cellular metabolism within vulnerable regions. Impairment in oxygen delivery damage all organ system including pulmonary and gastrointestinal tract. The pulmonary effects of asphyxia include increased pulmonary vascular resistance, pulmonary hemorrhage, pulmonary edema secondary to cardiac failure, and possibly failure of surfactant production with secondary hyaline membrane disease (acute respiratory distress syndrome).Gastrointestinal damage might include injury to the bowel wall, which can be mucosal or full thickness and even involve perforation Material and methods: This is a prospective observational hospital based study carried out on 152 asphyxiated neonates admitted in NICU of Rural Medical College of Pravara Institute of Medical Sciences, Loni, Ahmednagar, Maharashtra from September 2013 to August 2015. -
9.1 Appendix a Minimum Respiratory Protection for Cutting and Welding Processes
Safety Policy and Procedure Policy Number 015 Authorized By: The Cianbro Companies Alan Burton Title: Welding and Cutting Hazard Assessment Program Effective Date: 09/16/95 Page 1 of 12 1 Status 1.1 Update of existing policy, effective 06/03/11. 2 Purpose 2.1 To provide guidelines and requirements to protect team members from the hazards associated with welding, cutting, and burning operations. 3 Applicability 3.1 This policy applies to all subsidiary companies and departments of the Cianbro Companies. 3.2 All organizations are required to comply with the provisions of this policy and procedure. Any deviation, unless spelled out specifically in the policy, requires the permission of the Safety Director or designee. 4 Definitions 4.1 Adequate Ventilation: Used in this policy means any of the following: Local exhaust ventilation is used to capture fumes or in open area with adequate air movement or adequate dilution ventilation with directional air flow away from team member. 4.2 Air Arc (Carbon Arc): A cutting process by which metals are melted by the heat of an arc using a carbon electrode. Molten metal is forced away from the cut by a blast of forced air. 4.3 Bug-O BUG-O Systems Inc.: A manufacturer of a system of drives, carriages, rails and attachments designed to automate welding guns, cutting torches and other hand held tools. 4.4 Cad Welding: An exothermic (gives off heat) welding process that fuses conductors together to form a molecular bond with a current-carrying capacity equal to that of the conductor. Typically used in grounding systems. -
Fibrosing Mediastinitis, Severe Pulmonary Hypertension, And
Vascular Diseases and Therapeutics Case Report ISSN: 2399-7400 Troublesome triad: fibrosing mediastinitis, severe pulmonary hypertension, and pulmonary vein stenosis Gregory W Wigger*1 and Jean Elwing2 1Resident Physician, Department of Internal Medicine, University of Cincinnati Medical Center, Cincinnati, OH 45267, USA 2Associate Professor of Medicine, Department of Pulmonary, Critical Care, and Sleep Medicine, University of Cincinnati Medical Center, Cincinnati, OH 45267, USA Abstract Fibrosing mediastinitis is a disorder of invasive and proliferative fibrous tissue growth in the mediastinum. Its occurrence is rare and cause unknown, though it has been associated with several infections. The fibrosis of mediastinal structures, particularly vasculature, results in common symptoms of cough, dyspnea and hemoptysis due to pulmonary hypertension, pulmonary edema, and parenchyma fibrosis. Progression of disease carries a high mortality rate and causes of death are typically due to cor pulmonale,pulmonary infections and respiratory failure. Several medical treatments and surgical procedures have been unsuccessful; however the use of endovascular stenting is showing promising results. Early recognition and diagnosis are essential to provide patients with the best chance of survival and management options.We review the case of a 43 year-old female diagnosed with fibrosing mediastinitis and sequelae of pulmonary vein stenosis and pulmonary hypertension. Unfortunately, she was a poor candidate for pulmonic vein stenting due to her unstable condition. Without treatment of the stenosis, her clinical status and pulmonary hypertension worsened. Pulmonary vasodilators resulted in pulmonary edema and diuresis resulted in hypotension. Ultimately her condition was untreatable. This case illustrates the devastating effects of advanced fibrosing mediastinitis. Clinical presentation/Course The patient’s family elected to withdraw care and the patient passed after extubation. -
Endotracheal Adrenaline Use a Newborn with Pulmonary Hemorrhage: a Case Report
J Surg Med. 2018;2(2):174-176. Case report DOI: 10.28982/josam.396931 Olgu sunumu Endotracheal adrenaline use a newborn with pulmonary hemorrhage: A case report Yenidoğanda endotrakeal yolla verilen adrenalin ile tedavi edilen pulmoner kanama: Olgu sunumu Muhammet Mesut Nezir Engin 1, Muhammed İbrahim Özsüer 1, Önder Kılıçaslan 1, Kenan Kocabay 1 1 Department of Child Health and Diseases, Abstract Duzce University, Faculty of Medicine, Duzce, Turkey Pulmonary hemorrhage in the newborn is an acute and idiopathic event characterized by discharge of bloody fluid from the respiratory tract or endotracheal tube. In this case report we discussed 5 hours old neonate with pulmonary bleeding. We showed that endotracheal adrenaline use, gastric lavage with cold water and use of vitamin K in the treatment of neonates with pulmonary bleeding might shorten the duration of treatment and lower the mortality rate. Keywords: Pulmonary hemorrhage, Newborn, Adrenalin, Vitamin K Öz Pulmoner kanama bebeklerde görülen ve nedeni tam olarak aydınlatılamamış olan akciğerlerde kanama ile karakterize bir klinik durumdur. Bu olgu sunumunda yaşamının 5.saatinde pulmoner kanaması görülen bir bebek tartışılmıştır. Etyolojisi net olarak saptanamayan pulmoner kanama vakalarında endotrakeal yol ile adrenalin tedavisi, midenin soğuk mayi ile yıkanması ve K vitamini tedavisinin birlikte yapılması durumunda iyileşmeyi hızlandıracağı ve mortaliteyi azaltacağı kanaatinde varıldı. Anahtar kelimeler: Pulmoner kanama, Yenidoğan, Adrenalin, K vitamini Corresponding author / Sorumlu yazar: Muhammet Mesut Nezir Engin Address / Adres: Düzce Üniversitesi, Tıp Introduction Fakültesi, Çocuk Sağlığı ve Hastalıkları Kliniği, Düzce, Türkiye Pulmonary hemorrhage in the newborn is an acute, idiopathic clinical event e-Mail: [email protected] ⸺ characterized by discharge of bloody fluid from the respiratory tract and lungs of especially Informed Consent: The author stated that the premature and low birth weight infants.