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Prevalence of Risk for Substance-Related and Behavioral Addictions Among University Students in Turkey
THE TURKISH JOURNAL ON ADDICTIONS www.addicta.com.tr ORIGINAL RESEARCH Prevalence of Risk for Substance-Related and Behavioral Addictions Among University Students in Turkey Esma Akpınar Aslan1 , Sedat Batmaz1 , Zekiye Çelikbaş1 , Oğuzhan Kılınçel2 , Gökben Hızlı Sayar3 , Hüseyin Ünübol3 1Department of Psychiatry, Tokat Gaziosmanpasa University School of Medicine, Tokat, Turkey 2Department of Child Development, İstanbul Gelişim University, İstanbul, Turkey 3Department of Psychiatry, Üsküdar University School of Medicine, İstanbul, Turkey ORCID iDs of the authors: E.A.A. 0000-0003-4714-6894; S.B. 0000-0003-0585-2184; Z.Ç. 0000-0003-4728-7304; O.K. 0000-0003-2988- 4631; G.H.S. 0000-0002-2514-5682; H.Ü. 0000-0003-4404-6062. Main Points • Men were found to be at higher risk for potential alcohol dependence, pathological gambling, gam- ing addiction, and sex/pornography addiction. • Mild nicotine addiction, problematic internet use and possible smartphone addiction, food addic- tion, and gaming addiction were higher in the age group of 18-24 years than in older students. • Screening for addiction risk in young people is crucial for effective prevention, early diagnosis, and treatment. • The screening programs and treatment targeting men and women, and different age groups need to be designed selectively. Abstract This study aims to investigate the prevalence of risk for substance-related and behavioral addictions among university students in Turkey. In total, 612 students were included in this study, and they completed an online questionnaire consisting of the Fagerström Test for Nicotine Dependence, the Alcohol Use Disorders Identifica- tion Test, the Drug Abuse Screening Test, the Smartphone Addiction Scale-Short Version, the Young’s Internet Addiction Test-Short Form, the South Oaks Gambling Screen, and the Burden of Behavioral Addiction Form. -
Amphetamine Sensitization Alters Hippocampal Neuronal Morphology and Memory and Learning Behaviors
Molecular Psychiatry https://doi.org/10.1038/s41380-020-0809-2 ARTICLE Amphetamine sensitization alters hippocampal neuronal morphology and memory and learning behaviors 1,2,5 1,2 1 Luis Enrique Arroyo-García ● Hiram Tendilla-Beltrán ● Rubén Antonio Vázquez-Roque ● 1 3 3 3 1 Erick Ernesto Jurado-Tapia ● Alfonso Díaz ● Patricia Aguilar-Alonso ● Eduardo Brambila ● Eduardo Monjaraz ● 2 4 1 Fidel De La Cruz ● Antonio Rodríguez-Moreno ● Gonzalo Flores Received: 12 November 2019 / Revised: 29 May 2020 / Accepted: 3 June 2020 © The Author(s), under exclusive licence to Springer Nature Limited 2020 Abstract It is known that continuous abuse of amphetamine (AMPH) results in alterations in neuronal structure and cognitive behaviors related to the reward system. However, the impact of AMPH abuse on the hippocampus remains unknown. The aim of this study was to determine the damage caused by AMPH in the hippocampus in an addiction model. We reproduced the AMPH sensitization model proposed by Robinson et al. in 1997 and performed the novel object recognition test (NORt) to evaluate learning and memory behaviors. After the NORt, we performed Golgi–Cox staining, a 1234567890();,: 1234567890();,: stereological cell count, immunohistochemistry to determine the presence of GFAP, CASP3, and MT-III, and evaluated oxidative stress in the hippocampus. We found that AMPH treatment generates impairment in short- and long-term memories and a decrease in neuronal density in the CA1 region of the hippocampus. The morphological test showed an increase in the total dendritic length, but a decrease in the number of mature spines in the CA1 region. GFAP labeling increased in the CA1 region and MT-III increased in the CA1 and CA3 regions. -
Medications to Treat Opioid Use Disorder Research Report
Research Report Revised Junio 2018 Medications to Treat Opioid Use Disorder Research Report Table of Contents Medications to Treat Opioid Use Disorder Research Report Overview How do medications to treat opioid use disorder work? How effective are medications to treat opioid use disorder? What are misconceptions about maintenance treatment? What is the treatment need versus the diversion risk for opioid use disorder treatment? What is the impact of medication for opioid use disorder treatment on HIV/HCV outcomes? How is opioid use disorder treated in the criminal justice system? Is medication to treat opioid use disorder available in the military? What treatment is available for pregnant mothers and their babies? How much does opioid treatment cost? Is naloxone accessible? References Page 1 Medications to Treat Opioid Use Disorder Research Report Discusses effective medications used to treat opioid use disorders: methadone, buprenorphine, and naltrexone. Overview An estimated 1.4 million people in the United States had a substance use disorder related to prescription opioids in 2019.1 However, only a fraction of people with prescription opioid use disorders receive tailored treatment (22 percent in 2019).1 Overdose deaths involving prescription opioids more than quadrupled from 1999 through 2016 followed by significant declines reported in both 2018 and 2019.2,3 Besides overdose, consequences of the opioid crisis include a rising incidence of infants born dependent on opioids because their mothers used these substances during pregnancy4,5 and increased spread of infectious diseases, including HIV and hepatitis C (HCV), as was seen in 2015 in southern Indiana.6 Effective prevention and treatment strategies exist for opioid misuse and use disorder but are highly underutilized across the United States. -
Todd Bowman, Ph.D., LPC
Todd Bowman, Ph.D., LPC Home: 21938 W. 176th St. Work: Counselor Education Department Olathe, KS 66062 Indiana Wesleyan University (913) 956-9374 4201 S. Washington St Email: [email protected] Marion, IN 46953 Education/Training 6/03-7/08 Doctor of Philosophy, Counseling Psychology, School of Applied Health and Educational Psychology Oklahoma State University, Stillwater, OK Counseling Psychology Ph.D. Program (APA Accredited) Completion: 7/2008; Conferral: 12/2008 8/99-5/03 Bachelor of Arts, School of Natural and Social Sciences Mount Vernon Nazarene University Major in Psychology, Minor in Spanish Graduation: 5/2003 1/18-present Certified Sexual Addiction Therapist- Candidate (CSAT) International Inventory for Trauma and Addiction Professionals Academic Experience 8/14-present Associate Professor, Counselor Education Department, Indiana Wesleyan University, CACREP Accredited Courses taught include: Research for Counselors, Individual Appraisal, Theories and Techniques of Helping Relationships. Psychopathology, Theory and Techniques in Group Counseling, Issues in Addiction Recovery Supervisor: Mark Gerig, Ph.D. Responsibilities: planning for all phases of teaching in the course including lecture development, learning management software platform building (Learning Studio), and grading. Courses were taught in online format with approximately 12-16 students in each course. 8/08-6/14 Associate Professor, Program Director- Sexual Addiction Treatment Provider (SATP) Certificate Program, Counselor Education Department, MidAmerica Nazarene University, CACREP Accreditation 7/10 Courses developed and taught include: (Master’s program): Foundations of Mental Health, Theories of Counseling, Psychodiagnosis and Todd Bowman 2 Treatment, Prevention and Intervention in Mental Health, Theories of Group Counseling, Individual and Family Assessment, Career Development/Career Counseling, Counselor as Consultant, Research in Counseling, Practicum/Internship. -
Impossible Grief:· Motivation and Intention in 1Macheth
IMPOSSIBLE GRIEF:· MOTIVATION AND INTENTION IN 1MACHETH KER WELLS A THESIS SUBMITTED TO THE FACULTY OF GRADUATE STUDIES IN PARTIAL FULFILLMENT OF THE RE~UIREMENTS FOR THE DEGREE OF MASTER OF FINE ARTS GRADUATE PROGRAM IN THEATRE YORK UNIVERSITY, TORONTO, ONTARIO SEPTEMBER 2013 ©KER WELLS, 2013 ii Abstract This paper considers the issues of identification and motivation in Shakespeare's Macbeth. Proceeding from the proposal that the play allows for a remarkable level of audience identification for the characters of Macbeth and Lady Macbeth, considering their heinous acts, reasons for this level of identification are explored. Two events referred to in the text of Macbeth, but preceding the time of the play, are identified as potentially significant motivating factors in the couple's actions: Macbeth's recent experience of intense battle, and the couple's apparent past loss of a child. Supporting textual evidence is presented in addition to third party research into the effects of close combat and Post-Traumatic Stress Disorder, and the psychological effects on parents of losing a child. Various staging and design implications, opportunities, and ideas that result from these proposals are explored with direct reference to the author's production of Macbeth in Toronto's High Park. iii Dedicated to Marilyn Wells, to L.L.M, and to all the others who have taught me. iv TABLE OF CONTENTS Abstract ................................................................................. ii Introduction .......................................................................... -
Neuroplasticity in the Mesolimbic System Induced by Sexual Experience and Subsequent Reward Abstinence
Western University Scholarship@Western Electronic Thesis and Dissertation Repository 6-21-2012 12:00 AM Neuroplasticity in the Mesolimbic System Induced by Sexual Experience and Subsequent Reward Abstinence Kyle Pitchers The University of Western Ontario Supervisor Lique M. Coolen The University of Western Ontario Graduate Program in Anatomy and Cell Biology A thesis submitted in partial fulfillment of the equirr ements for the degree in Doctor of Philosophy © Kyle Pitchers 2012 Follow this and additional works at: https://ir.lib.uwo.ca/etd Recommended Citation Pitchers, Kyle, "Neuroplasticity in the Mesolimbic System Induced by Sexual Experience and Subsequent Reward Abstinence" (2012). Electronic Thesis and Dissertation Repository. 592. https://ir.lib.uwo.ca/etd/592 This Dissertation/Thesis is brought to you for free and open access by Scholarship@Western. It has been accepted for inclusion in Electronic Thesis and Dissertation Repository by an authorized administrator of Scholarship@Western. For more information, please contact [email protected]. NEUROPLASTICITY IN THE MESOLIMBIC SYSTEM INDUCED BY SEXUAL EXPERIENCE AND SUBSEQUENT REWARD ABSTINENCE (Spine Title: Sex, Drugs and Neuroplasticity) (Thesis Format: Integrated Article) By Kyle Kevin Pitchers Graduate Program in Anatomy and Cell Biology A thesis submitted in partial fulfillment of the requirements for degree of Doctor of Philosophy The School of Graduate and Postdoctoral Studies The University of Western Ontario London, Ontario, Canada © Kyle K. Pitchers, 2012 THE UNIVERSITY -
New Persistent Opioid Abuse and the Brain Reward Circuit
Zhang L, Boysen PG. New Persistent Opioid Abuse and the Brain Reward Circuit. J Anesthesiol & Pain Therapy. 2020;1(1):11-13 Letter to the Editor Open Access New Persistent Opioid Abuse and the Brain Reward Circuit Ly Zhang*, Philip G. Boysen Department of Anesthesiology, University of Mississippi Medical Center, The Mississippi Critical Care Organization, USA Article Info New persistent opioid abuse in peri-operative and peri- procedural patients is reported to be ~6% in two large population- Article Notes 1 Received: December 06, 2019 based studies . In addressing the opioid crisis the CDC has developed Accepted: April 08, 2020 2 *Correspondence: approved opioids are prescribed by licensed professionals . The *Dr. Ly Zhang, Department of Anesthesiology, University of three categories. The first is prescription drugs, when legal and Mississippi Medical Center, The Mississippi Critical Care and fentanyl . Over time CDC data indicates a sharp uptick in opioid Organization, USA; Email: [email protected]. second and third3,4 categories involve illicit drugs, specifically heroin ©2020 Zhang L. This article is distributed under the terms of the prescription drugs5. Understanding the neurobiology of addiction Creative Commons Attribution 4.0 International License. deaths for heroin and fentanyl, but a flat incidence of overdose with and public health issues are integral to the understanding of how adds insight to the problem and treatment. In addition, the social the brain reward circuit is activated in the first place. human primates 50 years ago. Rats taught to push a lever to self – The brain reward circuit was described in rodents, then in non- aspectsadminister of addictive addictive behavior. -
Short Note on Dark Side of Addiction
lism and D OPEN ACCESS Freely available online o ru h g o lc D A e p f e o n l d a e Journal of n r n c u e o J ISSN: 2329-6488 Alcoholism & Drug Dependence Editorial Short Note on Dark Side of Addiction Richard Samson* Department of Psychology, Faculty of Pharmacy, University of Michigan, 500 S State St, Ann Arbor, MI 48109, United States ABSTRACT Addiction is a biopsychosocial disorder characterized by repeated use of drugs, or repetitive engagement in a behavior such as gambling, despite harm to self and others. According to the "brain disease model of addiction," while a number of psychosocial factors contribute to the development and maintenance of addiction, a biological process that is induced by repeated exposure to an addictive stimulus is the core pathology that drives the development and maintenance of an addiction. Many scholars who study addiction argue that the brain disease model is incomplete and misleading. Emotions are "feeling" states and classic physiological emotive responses that are interpreted based on the history of the organism and the context. Motivation is a persistent state that leads to organized activity. Both are intervening variables and intimately related and have neural representations in the brain. The present thesis is that drugs of abuse elicit powerful emotions that can be interwoven conceptually into this framework. Keywords: Allostasis; Corticotropin-releasing factor; Dynorphin; Extended amygdala; Incentive salience; Opponent process INTRODUCTION clinical research in humans and preclinical studies involving ΔFosB have identified compulsive sexual activity – specifically, any form The brain disease model posits that addiction is a disorder of the of sexual intercourse – as an addiction (i.e., sexual addiction). -
Pathos & Ethos: Emotions and Willingness to Pay for Tobacco
Francesco Bogliacino, Cristiano Codagnone, Giuseppe Alessandro Veltri, Amitav Chakravarti, Pietro Ortoleva, George Gaskell, Andriy Ivchenko, Francisco Lupiáñez- Villanueva, Francesco Mureddu, Caroline Rudisill Pathos & ethos: emotions and willingness to pay for tobacco products Article (Published version) (Refereed) Original citation: Bogliacino, Francesco, Codagnone, Cristiano, Veltri, Giuseppe Alessandro, Chakravarti, Amitav, Ortoleva, Pietro, Gaskell, George, Ivchenko, Andriy, Lupiáñez-Villanueva, Francisco, Mureddu, Francesco and Rudisill, Caroline (2015) Pathos & ethos: emotions and willingness to pay for tobacco products. PLOS One, 10 (10). e0139542. ISSN 1932-6203 DOI: 10.1371/journal.pone.0139542 Reuse of this item is permitted through licensing under the Creative Commons: © 2015 The Authors CC-BY This version available at: http://eprints.lse.ac.uk/64127/ Available in LSE Research Online: November 2015 LSE has developed LSE Research Online so that users may access research output of the School. Copyright © and Moral Rights for the papers on this site are retained by the individual authors and/or other copyright owners. You may freely distribute the URL (http://eprints.lse.ac.uk) of the LSE Research Online website. RESEARCH ARTICLE Pathos & Ethos: Emotions and Willingness to Pay for Tobacco Products Francesco Bogliacino1☯*, Cristiano Codagnone2☯, Giuseppe Alessandro Veltri3☯, Amitav Chakravarti4,5‡, Pietro Ortoleva6‡, George Gaskell4, Andriy Ivchenko7, Francisco Lupiáñez-Villanueva8, Francesco Mureddu8,9, Caroline Rudisill4 1 Universidad -
Understanding Addiction, Helping Clients and Colleagues
ALABAMA LAWYER ASSISTANCE PROGRAM Understanding Addiction, Helping Clients and Colleagues By Jeanne Marie Leslie rugs change the brain–they according to the American Bar change its structure and how it Association, is 15 to 18 percent.3 D works.1 Many of these changes Lawyers rank high in the incidences of are responsible for the behaviors we see depression compared to other professions in individuals addicted to drugs. and a disproportionate number of Neuroscience has made significant lawyers commit suicide;4 in Alabama advances in our ability to identify and there are about a dozen lawyer suicides understand the mechanisms involved in every year. And these are only the ones the addicted brain. These advancements about which we know. Many lawyers, clearly confirm what many in the addic- including some you know, may be strug- tion medicine field have known for some gling with an addiction or mental health time: the obsession and compulsion to problem when help is readily available use drugs in the addicted brain is instinc- through ALAP. tual and paramount to survival.2 Ignorance and stigma have contributed Addiction Facts to the confusion, moral judgments and Dr. Nora D. Volkow, director of the poor understanding of this destructive National Institute of Drug Abuse and often fatal disease. Our courts are (NIDA), explains how the neuro-chemi- overwhelmed by the behaviors, criminal cal mechanisms of drug abuse catalyze and civil, associated with addiction. and accelerate the onset addiction: Therefore, understanding addiction is “Recognizing drug addiction as a chron- essential for lawyers. Lawyers are in ic, relapsing disease characterized by com- unique positions to initiate change, to pulsive drug seeking and use is critical to advocate for medical treatment over tra- being able to identify and help those who ditional sanctions and to refer individuals have it. -
Nicotine and Neurotransmitters
Module 2 —Legal Doesn’t Mean Harmless Overview Overview Summary This module focuses on how two drugs, nicotine and alcohol, change the functioning of the brain and body. Both drugs are widely used in the community, and for adults, using them is legal. Nonetheless, both alcohol and nicotine can have a strong impact on the functioning of the brain. Each can cause a number of negative effects on the body and brain, ranging from mild symptoms to addiction. The goal of this module is to help students understand that, although nicotine and alcohol are legal for adults, they are not harmless substances. Students will learn about how nicotine and alcohol change or disrupt the process of neurotransmission. Students will explore information on the short- and long- term effects of these two drugs, and also learn why these drugs are illegal for children and teens. Through the media, students are exposed to a great deal of information about alcohol and tobacco, much of which is misleading or scientifically inaccurate. This module will provide information on what researchers have learned about how nicotine and alcohol change the brain, and the resulting implications for safety and health. Learning Objectives At the end of this module: • Students can explain how nicotine disrupts neurotransmission. • Students can explain how alcohol use may harm the brain and the body. • Students understand how alcohol can intensify the effect of other drugs. • Students can define addiction and understand its basis in the brain. • Students draw conclusions about why our society regulates the use of nicotine and alcohol for young people. -
Comparison Between Two Methodological Paradigms of Conditioned Place Preference with Methlyphenidate
East Tennessee State University Digital Commons @ East Tennessee State University Undergraduate Honors Theses Student Works 12-2013 Comparison between Two Methodological Paradigms of Conditioned Place Preference with Methlyphenidate. Bryce D. Watson East Tennessee State University Follow this and additional works at: https://dc.etsu.edu/honors Part of the Psychiatry and Psychology Commons Recommended Citation Watson, Bryce D., "Comparison between Two Methodological Paradigms of Conditioned Place Preference with Methlyphenidate." (2013). Undergraduate Honors Theses. Paper 89. https://dc.etsu.edu/honors/89 This Honors Thesis - Open Access is brought to you for free and open access by the Student Works at Digital Commons @ East Tennessee State University. It has been accepted for inclusion in Undergraduate Honors Theses by an authorized administrator of Digital Commons @ East Tennessee State University. For more information, please contact [email protected]. Watson 1 Comparison between Two Methodological Paradigms of Conditioned Place Preference with Methlyphenidate By Bryce Watson The Honors College Honors in Discipline Program East Tennessee State University Department of Psychology December 9, 2013 Russell Brown, Faculty Mentor David Harker, Faculty Reader Eric Sellers, Faculty Reader Watson 2 Abstract The aim of this thesis is to examine the mechanisms of Methylphenidate (MPH) on Conditioned Place Preference (CPP), a behavioral test of reward. The psychostimulant MPH is therapeutically used in the treatment of ADHD, but has been implicated in many pharmacological actions related to drug addiction and is considered to have abuse potential. Past work in our lab and others have shown substantial sex-differences in the neuropharmacological profile of MPH. Here a discussion of the relevant mechanisms of action of MPH and its relationship to neurotrophins and CPP are reviewed.