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Optumrx Premium Formulary Exclusions 2021 Jan. 1, 2020 Premium Formulary Exclusions & Preferred Specialty Prior Authorization Requirements Therapeutic Category Excluded Medications Preferred Alternatives ALLERGIC REACTIONS epinephrine injection made by Anaphylaxis Treatment Auvi-Q (0.15mg, 0.3mg), Epi-Pen JR 0.15mg My lan, epinephrine injection, Epi-Pen 0.3mg ANALGESICS celecoxib, diflunisal, etodolac, Cambia fenoprofen, flurbiprofen, ibuprofen, indomethacin, ketoprofen, ketorolac, meclofenamate, meloxicam, Oral nabumetone, naproxen, Zorvolex oxaprozin, piroxicam, sulindac, tolmetin Non-Steroidal Anti- Inflammatory Agents Qmiiz ODT meloxicam Flector diclofenac patch Topical Pennsaid diclofenac solution diclofenac, ibuprofen, Other Sprix Nasal Spray meloxicam Opioid Apadaz, hydrocodone/acetaminophen, combinations Benzhydrocodone/acetaminophen oxycodone/acetaminophen hydromorphone HCl ER, Arymo ER, Kadian ER 200 mg, morphine sulfate ER, Nuc y nta ER, Oxycodone Pow der, Oral Long- oxymorphone HCl ER, Oxycodone ER ( M) , Xtampza ER, Acting Embeda, Hysingla ER, Zohydro ER Opioid OxyContin Analgesics Conzip, Tramadol ER 100mg, Pain tramadol 200mg, 300mg (M) Oral Short- codeine sulfate, Acting hydromorphone HCl, morphine Nucynta Opioid sulfate, oxycodone HCl, Analgesics oxymorphone HCl Transmucosal Abstral, Fentora, Fentanyl Citrate Fentanyl Buccal Tab (M), fentanyl citrate lozenge Analgesics Lazanda, Subsys (M) Co-branded product * Tier 3 pref erred 1 Existing utilizers of these medications will be allowed to continue on therapy. Grandfathering will not be provided for any other excluded drugs. Therapeutic Category Excluded Medications Preferred Alternatives ANTIBACTERIALS, ORAL Doryx MPC, Doxycycline Hyclate delayed release Oral Antibiotics doxycycline, minocycline 80mg, Minolira, Targadox ANTICONV ULSANT S Trokendi XR1 topiramate ER 1 Seizure Disorders Oxtellar XR oxcarbazepine IR lamotrigine ODT, lamotrigine Lamictal ODT Kit, Lamictal XR Kit XR ANTIFUNGAL S, ORAL Oral Antifungals Tolsura Itraconazole cap ANTIM IGRAINES amitriptyline, atenolol, divalproex sodium, nadolol, CGRP Antagonists Ajovy propranolol, timolol, topiramate, venlafaxine, Aimovig, Emgality rizatriptan ODT, sumatriptan Serotonin Receptor Agonists Onzetra Xsail, Zembrace Symtouch injection, sumatriptan nasal spray, zolmitriptan ODT ANTIPARKINS ON AGENTS Parkinson's Disease Gocovri, Osmolex ER amantadine ANTIPSYCHOTICS Schizophrenia Risperdal CONSTA, Risperdal injection risperidone injection ANTIV IRALS Ledipasvir-Sofosbuvir (M) , Sofosbuvir-Velpatasvir Hepatitis-C drugs Epclusa, Harvoni, Mavyret ( M) Please talk w ith your doctor HIV drugs Atripla1 about clinically appropriate options. AUTONOM IC & CENTRAL NERV OUS SYSTEM Interferon Beta Medications for Extavia1, Plegridy1 Avonex, Betaseron Multiple Sclerosis CARDIOV ASCULA R diltiazem hcl coated beads ER Cardizem LA 120mg 120mg Hypertension Inderal XL , Innopran XL propranolol ER Kapspargo metoprolol ER atorvastatin, fluvastatin, Cholesterol-Low ering lovastatin, pravastatin, Zypitamag Agents rosuvastatin, simvastatin, Livalo (M) Co-branded product * Tier 3 pref erred 1 Existing utilizers of these medications will be allowed to continue on therapy. Grandfathering will not be provided for any other excluded drugs. Therapeutic Category Excluded Medications Preferred Alternatives CORTICOSTEROI DS Oral Steroids Rayos prednisone Imiquimod cream 3.75% (M), Zyclara, Zyclara Actinic Keratosis Imiquimod 5% cream Pump DERMATOLOGIC AL AGENTS adapalene, adapalene/benzoyl peroxide, clindamycin gel/lotion/solution, Aktipak, Clindagel, Clindamycin phosphate 1% clindamycin/benzoyl peroxide, gel(M), Veltin Topical Acne Treatment erythromycin/benzoyl peroxide, tretinoin cream, Epiduo Forte, Onexton Adapalene lotion (M), Differin lotion adapalene Topical anesthetics ZTlido lidocaine patch Topical Antifungals Jublia terbinafine, Kerydin metronidazole cream/gel/lotion, Topical Antiinfectives Noritate cream Soolantra ALA Scalp lotion, Micort-HC c ream hydrocortisone Apexicon E cream fluocinonide, betamethasone Der ma-Smoothe/FS, Capex shampoo flucinolone acetonide scalp oil Cloderm cream clocortolone pivalate Cordran tape flurandrenolide flurandrenolide, hydrocortisone Desonate gel, Pandel cream valerate, triamcinolone Topical Corticosteroids acetonide betamethasone, clobetasol, Halobetasol foam(M), Lexette halobetasol cream/ointment fluticasone ointment, Halog cream/ointment halobetasol cream/ointment, triamcinolone Impoyz cream clobetasol Psorcon cream, Verdeso foam betamethasone, fluocinolone hydrocortisone valerate, Trianex ointment triamcinolone acetonide clobetasol proprionate, Ultravate lotion fluocinonide, halobetasol proprionate (M) Co-branded product * Tier 3 pref erred 1 Existing utilizers of these medications will be allowed to continue on therapy. Grandfathering will not be provided for any other excluded drugs. Therapeutic Category Excluded Medications Preferred Alternatives DERMATOLOGIC AL AGENTS Topical Plaque Psoriasis Sorilux calcipotriene Treatment DIABETES Examples: Abbott (FreeStyle, Precision), Blood Glucose Meters, Test Arkray(Glucocard), Bayer (Breeze, Contour), Lifescan (One Touch products) Strips and Control Solutions Nipro (TRUEtest, TRUEtrack), Roche (Accu- Chek) Continuous Glucose Freestyle Libre Dexcom Monitoring (CGM) Blood Sugar Regulators metformin HCl 24hr ER osmotic release, metformin ER (generic Miscellaneous metformin HCl 24hr ER modified release GLUCOPHA GE XR ) Dipeptidyl Peptidase-4 Alogliptin(M), Alogliptin w ith metformin(M), Janumet, Janumet XR, (DPP4) Inhibitors & Alogliptin w ith pioglitazone( M) , Kazano, Januvia, Jentadueto, Combinations Kombiglyze XR, Nesina, Onglyza, Oseni Jentadueto XR, Tradjenta Basal insulins Basaglar, Levemir, Tresiba Lantus, Toujeo Bydureon, Bydureon BCise, Glucagon-Like Peptide- Adlyxin, Tanzeum Byetta, Ozempic, Trulicity, 1(GLP1) Agonists Victoza Insulins Novolin Humulin Rapid-acting insulins Admelog, Apidra, Fiasp, Lispro, Novolog Humalog Sodium-glucose co- Invokamet, Invokamet XR, transporter (SGLT2) Farxiga, Segluromet, Steglatro, Xigduo XR Invokana, Jardiance, Synjardy, Inhibitors Synjardy XR SGLT2 and DPP4 QTERN, Steglujan Glyxambi Combinations ENDOC RI NE (OTHER) Estrogens Delestrogen 10mg/ml estradiol valerate Norditropin, Nutropin, Grow th Hormones Genotropin, Humatrope, Saizen, Zomacton Omnitrope Bravelle, Gonal-F, Gonal-F RFF Follistim AQ Infertility ganirelix (made by Cetrotide Organon/Merck) Nocturia Noctiva desmopressin, Nocdurna GASTROINTESTINAL diphenoxylate/atropine, Anti-Diarrheal Agents Motofen loperamide granisetron solution/tablet, Antiemetics Sancuso patch ondansetron ODT Anti-Inflammatory, famotidine w ith ibuprofen, Duexis, Vimovo Anti-Ulcer Agents omeprazole w ith naproxen Irritable Bow el Syndrome w ith Constipation/ Chronic Amitiza, Trulance Linzess Idiopathic Constipation (IBS- C/CIC) (M) Co-branded product * Tier 3 pref erred 1 Existing utilizers of these medications will be allowed to continue on therapy. Grandfathering will not be provided for any other excluded drugs. Therapeutic Category Excluded Medications Preferred Alternatives GASTROINTESTINAL Opioid-Induced Constipation Amitiza, Movantik, Relistor Symproic (OIC) Apriso, balsalazide, Inflammatory Bow el Disease Dipentum mesalamine Gavilyte-C, Gavilyte-H, PEG Golytely packets 3350 Laxatives Clenpiq, Plenvu, Prepopik, Moviprep Suprep Pancreatic Enzymes Pancreaze, Pertzye, Viokace Creon, Zenpep esomeprazole magnesium delayed release, lansoprazole, omeprazole, Proton pump inhibitors omeppi, omeprazole w ith sodium bicarbonate pantoprazole (cap, pow der pak) HEMATOLOGICAL Erythropoiesis-Stimulating Epogen, Procrit Aranesp, Retacrit Agents Immune globulin, 1 Panzyga Gammagard intravenous (IVIG) Long-Acting Granulocyte- Colony Stimulating Factor Fulphila Neulasta, Udenyca (G-CSFs) Short-Acting Granulocyte- Colony Stimulating Factor Granix, Neupogen Nivestym, Zarxio (G-CSFs ) IM M UNOM ODULATORS Interleukin-17 (IL-17) 1 Cosentyx Taltz* Inhibitor JAK Inhibitor Olumiant1 Xeljanz, Xeljanz XR TNF inhibitor Remicade Inflectra, Renflexis OPHTHALM IC latanoprost ophthalmic Vyzulta, Zioptan solution, Lumigan, Travatan Z Antiglaucoma Drugs Timoptic Ocudose timolol ophthalmic solution azelastine ophth sol, Mast cell stabilizers Pazeo olopatadine ophth sol Non-steroidal Anti- Bromsite, Ilevro, Nevanac Prolensa Inflammatory Agents OT HER Alkylating Agents Belrapzo, Bendamustine Bendeka, Treanda Antigout Agents Colchicine capsule/tablet, Mitigare Colcrys Clarinex Syrup desloratadine Antihistamines and combinations desloratadine w ith Clarinex-D pseudoephedrine (M) Co-branded product * Tier 3 pref erred 1 Existing utilizers of these medications will be allowed to continue on therapy. Grandfathering will not be provided for any other excluded drugs. Therapeutic Category Excluded Medications Preferred Alternatives OT HER Carnitine Deficiency Carnitor injection levocarnitine mometasone furoate, Corticosteroid nasal sprays Xhance Beconase AQ junel FE, larin FE, microgestin Oral Contraceptives Lo Loestrin FE, tarina FE Gel-One, Genvisc, Hyalgan, Hymovis, Monovisc, Osteoarthritis/Hyaluronic Orthovisc, Supartz FX, Synvisc, Synvisc-One, Durolane, Euflexxa, Gelsyn-3 acid injections Trivisc, Visco-3 Thyroid Agents Tirosint caps, solution levothyroxine RESPIRAT ORY Seebri, Tudorza Incruse Ellipta, Spiriva COPD: Inhaled Anticholinergics Yupelri Lonhala Magnair COPD: Long-Acting Beta Agonist/Long-Acting Bevespi, Utibron Anoro Ellipta, Stiolto Respimat Muscarinic Agonist Combination inhalers Cystic Fibrosis (inhaled Kitabis Pak, TOBI Podhaler,
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