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SSAT Abstract Book 1.Indb THE SOCIETY FOR SURGERY OF THE ALIMENTARY TRACT 54th Annual Meeting May 17-21, 2013 Orange County Convention Center Orlando, Florida ABSTRACT SUPPLEMENT Table of Contents Schedule-at-a-Glance .............................................................................................................2 Sunday Plenary, Video, and Quick Shot Session Abstracts ....................................................6 Monday Plenary, Video, and Quick Shot Session Abstracts ................................................22 Tuesday Plenary Session Abstracts .......................................................................................50 Sunday Poster Session Abstracts ..........................................................................................59 Monday Poster Session Abstracts .......................................................................................112 Tuesday Poster Session Abstracts .......................................................................................166 THE SOCIETY FOR SURGERY OF THE ALIMENTARY TRACT PROGRAM BOOK ABSTRACT SUPPLEMENT FIFTY-FOURTH ANNUAL MEETING Orange County Convention Center Orlando, Florida May 17–21, 2013 THE SOCIETY FOR SURGERY OF THE ALIMENTARY TRACT Schedule-at-a-Glance FRI, MAY 17, 2013 SATURDAY, MAY 18, 2013 300 208ABC Other 6:30 AM 6:45 AM 7:00 AM 7:15 AM 7:30 AM 7:45 AM 8:00 AM 8:15 AM 8:30 AM 8:45 AM 9:00 AM 9:15 AM 9:30 AM 9:45 AM 10:00 AM 10:15 AM 10:30 AM 10:45 AM NAFLD DDW CCS: 11:00 AM Therapeutic 11:15 AM Approaches in 11:30 AM 11:45 AM (by invitation only) 12:00 PM 12:15 PM 12:30 PM 12:45 PM 1:00 PM 1:15 PM 1:30 PM RESIDENTS & FELLOWS RESEARCH CONFERENCE 1:45 PM 2:00 PM 2:15 PM MAINTENANCE OF CERTIFICATION COURSE: 2:30 PM Evidence Based Treatment of Colorectal Diseases 2:45 PM of IBD DDW CCS: 3:00 PM Endoscopic 3:15 PM Evaluation & Mgt 3:30 PM 3:45 PM 4:00 PM 4:15 PM 4:30 PM 4:45 PM Barrett's Esophagus 5:00 PM DDW CCS: 5:15 PM Controversies in 5:30 PM 5:45 PM 2 54TH ANNUAL MEETING • MAY 17–21, 2013 • ORLANDO, FL Schedule-at-a-Glance SUNDAY, MAY 19, 2013 Exhibit 300 308D 303ABC 304AB Other Hall 6:30 AM 6:45 AM 7:00 AM 7:15 AM 7:30 AM OPENING SESSION 7:45 AM 8:00 AM PRESIDENTIAL 8:15 AM PLENARY A 8:30 AM (PLENARY SESSION I) 8:45 AM DDW 9:00 AM COMBINED RESEARCH PRESIDENTIAL IBD FORUM: 9:15 AM ADDRESS 9:30 AM 9:45 AM 10:00 AM 10:15 AM PRESIDENTIAL 10:30 AM PLENARY B 10:45 AM (PLENARY SESSION II) Syndrome 11:00 AM DDW CCS: Tx of Metabolic 11:15 AM GUEST ORATOR Bariatric Surgery as 11:30 AM 11:45 AM 12:00 PM 12:15 PM 12:30 PM 12:45 PM 1:00 PM 1:15 PM MEET-THE- LUNCHEON 1:30 PM PROFESSOR 1:45 PM 2:00 PM 2:15 PM 2:30 PM 2:45 PM Mets Lesions 3:00 PM GI SURGERY of Benign Liver DEBATES A: HIPEC; HIPEC; A: DEBATES Synch Colorectal Liver CONTROVERSIES IN CONTROVERSIES 3:15 PM DDW CCS: Mgt Cancer 3:30 PM POSTER SESSION I (authors available @ posters 12:00 PM - 2:00 PM) 3:45 PM VIDEO SESSION I 4:00 PM STATE-OF-THE-ART CONFERENCE: Evolving PLENARY SESSION III 4:15 PM Management in Pancreatic 4:30 PM 4:45 PM 5:00 PM 5:15 PM 5:30 PM 5:45 PM 3 12:45 PM 12:30 PM 12:15 PM 12:00 PM 11:45 AM 11:30 AM 11:15 AM 11:00 AM 10:45 AM 10:30 AM 10:15 AM 10:00 AM 5:45 PM 5:30 PM 5:15 PM 5:00 PM 4:45 PM 4:30 PM 4:15 PM 4:00 PM 3:45 PM 3:30 PM 3:15 PM 3:00 PM 2:45 PM 2:30 PM 2:15 PM 2:00 PM 1:45 PM 1:30 PM 1:15 PM 1:00 PM 9:45 AM 9:30 AM 9:15 AM 9:00 AM 8:45 AM 8:30 AM 8:15 AM 8:00 AM 7:45 AM 7:30 AM 7:15 AM 7:00 AM 6:45 AM 6:30 AM THE SOCIETY FOR SURGERY OF THE ALIMENTARY TRACT OFTHEALIMENTARY THE SOCIETYFORSURGERY QUICK 300 308D 303ABC 304AB SHOTS SESSION I Schedule-at-a-Glance QUICK PUBLIC SHOTS PLENARY PLENARY POLICY & SESSION SESSION V SESSION IV ADVOCACY III PANEL SSAT/AHPBA JOINT SSAT/ASCRS STATE-OF- LECTURE JOINT QUICK THE-ART SYMPOSIUM: ANNUAL VIDEO SESSION II: SYMPOSIUM: SHOTS Parenchymal BUSINESS Preservation in Hepatic BREAKFAST AT MONDAY, MAY20,2013 Mgt of MEETING SESSION Resection for THE MOVIES 4 Diverticular II Metastatic Colorectal Disease CA CLINICAL CLINICAL CONTROVERSIES IN WARD WARD GI SURGERY VIDEO DEBATES B: ROUNDS I: ROUNDS II: SESSION Resectable Pancreas Trans-Anal Cysts of the Adenocarcinoma; III Surgery for Pancreas Nissen Fundoplication Rectal CA Exhibit Hall POSTER SESSION II (authors available @ posters 12:00 PM - 2:00 PM) DDW CCS: Mgt DDW CCS: DDW CCS: MEET-THE- BREAKFAST of Sx Risk in Post-Op Achalasia Treatment: PROFESSOR WITH THE Botox, Balloon, Lap Patients with Complications in LUNCHEON EXPERT Other Myotomy or POEM Cirrhosis IBD Patient WRITERS WORKSHOP 1: Writing 54TH ANNUAL MEETING • MAY 17–21, 2013 • ORLANDO, FL Schedule-at-a-Glance TUESDAY, MAY 21, 2013 Exhibit 308D 303ABC 304AB Other Hall 6:30 AM 6:45 AM 7:00 AM 7:15 AM EXPERT WITH THE 7:30 AM BREAKFAST 7:45 AM 8:00 AM 8:15 AM 8:30 AM B'FAST GI Leaks 8:45 AM Early Cancer PLENARY 9:00 AM Pancreatic DDW CCS: SESSION VI SSAT/ISDS JOINT 9:15 AM SYMPOSIUM: Mgt of 9:30 AM 9:45 AM 10:00 AM 10:15 AM 10:30 AM 10:45 AM Necrosis 11:00 AM Pancreatic DDW CCS: 11:15 AM 11:30 AM PANEL & QUALITY OUTCOMES OUTCOMES PLENARY SESSION VII 11:45 AM HEALTH CARE 12:00 PM 12:15 PM 12:30 PM 12:45 PM 1:00 PM 1:15 PM WRITERS MEET-THE- LUNCHEON 2: Reviewing WORKSHOP 1:30 PM PROFESSOR 1:45 PM 2:00 PM 2:15 PM SSAT/SAGES JOINT GI Surgery Complications GI 2:30 PM LUNCHEON SYMPOSIUM: 2:45 PM Upper from Complex Mgt & Rescue Tumors 3:00 PM Junction 3:15 PM DDW CCS: GE 3:30 PM BEST OF DDW POSTER SESSION III (authors available @ posters 12:00 PM - 2:00 PM) 3:45 PM . 4:00 PM 4:15 PM 4:30 PM 4:45 PM 5:00 PM 5:15 PM 5:30 PM 5:45 PM 5 THE SOCIETY FOR SURGERY OF THE ALIMENTARY TRACT SSAT PLENARY, VIDEO, AND QUICK SHOT ABSTRACTS Printed as submitted by the authors. indicates a paper that is also being presented at the Residents & Fellows Research Conference. Participation in and attendance at this conference is by invitation only. 6indicates a video presentation scheduled during a Plenary Session. Sunday, May 19, 2013 8:00 AM – 9:00 AM 303ABC PRESIDENTIAL PLENARY A (PLENARY SESSION I) 199 benign lesions. E3 and E4 were expressed at extremely low levels in all patients. Compared to IPMN alone, E6 levels Clinical Signifi cance of Serum COL6A3 Isoforms in were signifi cantly higher in PDA (p = 0.0036). There were Pancreatic Ductal Adenocarcinoma no signifi cant differences between E6 levels in IPMN and Christopher Y. Kang, Dierdre Axell-House, Pranay Soni, Normal sera (p = 0.59). Using a logistic regression model, Galina Chipitsyna, Konrad Sarosiek, Mazhar Al-Zoubi, Hwyda A. we found that for each increasing unit of log E6 COL6A3, Arafat, Charles J. Yeo patients are 9.5 times more likely to harbor a cancer rather Surgery, Thomas Jefferson University, Philadelphia, PA than a benign lesion, 95% CI (2.4, 38.1), p = 0.002. The area under the ROC curve, AUC, was 0.72. Knocking down E3 INTRODUCTION: Type VI collagen (COL6) forms a or E4 or E6 with isoform-specifi c siRNA resulted in reduced microfi brillar network associated with type I collagen fi brils PDA cell migration and invasion and concomitant reduc- and constitutes a major component of the prominent des- tion of the expression of several infl ammation and angio- moplastic reaction in pancreatic ductal adenocarcinoma genesis-related genes, such as MMP-9, OPN, MCP-1 and (PDA). We have demonstrated recently that a subunit of VEGF. Interestingly, knocking down any of the 3 isoforms COL6, COL6A3, is expressed in high levels in PDA tissue. resulted in increased expression of TNF-alpha. We also showed that COL6A3 gene undergoes tumor-spe- cifi c alternative splicing to produce 3 isoforms E3, E4 and CONCLUSIONS: Our data show for the fi rst time the E6 that are tumor tissue-specifi c. The aim of this study is to potential clinical signifi cance of circulating E6 COL6A3 lev- investigate the diagnostic value and clinical signifi cance of els in the diagnosis of pancreatic malignancy. Our in vitro circulating COL6A3 isoforms mRNA in PDA. data suggests a role for COL6A3 isoforms in PDA progres- sion and metastatic potential. METHODS: Serum samples were obtained from patients that underwent pancreatic resection at a single institution between 2006 and 2009. COL6A3 levels in the sera from 200 patients with pathologically confi rmed PDA (n = = 40), Treatment Sequencing for Resectable Pancreatic intraductal papillary mucinous neoplasms (IPMN) (n = 20), Cancer: Infl uence of Early Metastases and Surgical and chronic pancreatitis (n = 10) were analyzed by real time Complications on Multimodality Therapy Completion PCR using isoform-specifi c primers for E3, E4 and E6. In Rates and Survival addition, sera from age-matched healthy volunteers were 1 2 1 analyzed (n = 30). The prediction levels for malignancy Ching-Wei D.
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