Putnam Dynamic Asset Allocation Balanced Fund the Fund's Portfolio 12/31/20 (Unaudited)
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Prostate Cancer in Focus
PROSTATE CANCER IN FOCUS Current Developments in the Management of Prostate Cancer Section Editor: Andrew J. Armstrong, MD Prostate Cancer Prostate PSMA-Targeted Therapy in Prostate Cancer Scott T. Tagawa, MD, MS Professor of Medicine and Urology Weill Cornell Medicine New York, New York H&O What is prostate-specific membrane agent such as a monoclonal antibody might be able to antigen (PSMA), and what makes it a good target target a tumor without binding to other PSMA-positive for the treatment of prostate cancer? sites owing to its large size and physical inability to reach luminal sites of expression that are separated from the ST PSMA is a cell surface antigen that is expressed to vasculature by tight junctions. a limited degree on certain normal cells in the body but generally is highly overexpressed in the setting of prostate H&O How is PSMA positivity established? cancer. Normal cells that express PSMA are located in the prostate, salivary, and lacrimal glands; the proximal part ST Imaging and biopsy are the main ways to establish of the small intestine; the proximal renal tubules; and PSMA positivity. Multiple imaging modalities are avail- some ganglia. In the setting of prostate cancer, PSMA able worldwide. The agent indium In 111 capromab expression generally increases along with the cancer grade, pendetide (ProstaScint) has been approved for years in and it also increases following hormonal therapy. In addi- the United States, and the US Food and Drug Adminis- tion, PSMA expression tends to be higher in metastatic tration (FDA) approved the use of gallium Ga 68 PSMA- sites than in primary tumors. -
OSB Representative Participant List by Industry
OSB Representative Participant List by Industry Aerospace • KAWASAKI • VOLVO • CATERPILLAR • ADVANCED COATING • KEDDEG COMPANY • XI'AN AIRCRAFT INDUSTRY • CHINA FAW GROUP TECHNOLOGIES GROUP • KOREAN AIRLINES • CHINA INTERNATIONAL Agriculture • AIRBUS MARINE CONTAINERS • L3 COMMUNICATIONS • AIRCELLE • AGRICOLA FORNACE • CHRYSLER • LOCKHEED MARTIN • ALLIANT TECHSYSTEMS • CARGILL • COMMERCIAL VEHICLE • M7 AEROSPACE GROUP • AVICHINA • E. RITTER & COMPANY • • MESSIER-BUGATTI- CONTINENTAL AIRLINES • BAE SYSTEMS • EXOPLAST DOWTY • CONTINENTAL • BE AEROSPACE • MITSUBISHI HEAVY • JOHN DEERE AUTOMOTIVE INDUSTRIES • • BELL HELICOPTER • MAUI PINEAPPLE CONTINENTAL • NASA COMPANY AUTOMOTIVE SYSTEMS • BOMBARDIER • • NGC INTEGRATED • USDA COOPER-STANDARD • CAE SYSTEMS AUTOMOTIVE Automotive • • CORNING • CESSNA AIRCRAFT NORTHROP GRUMMAN • AGCO • COMPANY • PRECISION CASTPARTS COSMA INDUSTRIAL DO • COBHAM CORP. • ALLIED SPECIALTY BRASIL • VEHICLES • CRP INDUSTRIES • COMAC RAYTHEON • AMSTED INDUSTRIES • • CUMMINS • DANAHER RAYTHEON E-SYSTEMS • ANHUI JIANGHUAI • • DAF TRUCKS • DASSAULT AVIATION RAYTHEON MISSLE AUTOMOBILE SYSTEMS COMPANY • • ARVINMERITOR DAIHATSU MOTOR • EATON • RAYTHEON NCS • • ASHOK LEYLAND DAIMLER • EMBRAER • RAYTHEON RMS • • ATC LOGISTICS & DALPHI METAL ESPANA • EUROPEAN AERONAUTIC • ROLLS-ROYCE DEFENCE AND SPACE ELECTRONICS • DANA HOLDING COMPANY • ROTORCRAFT • AUDI CORPORATION • FINMECCANICA ENTERPRISES • • AUTOZONE DANA INDÚSTRIAS • SAAB • FLIR SYSTEMS • • BAE SYSTEMS DELPHI • SMITH'S DETECTION • FUJI • • BECK/ARNLEY DENSO CORPORATION -
1 United States District Court Eastern District of New York
Case 1:18-cv-07359-PKC-CLP Document 90 Filed 01/07/21 Page 1 of 21 PageID #: <pageID> UNITED STATES DISTRICT COURT EASTERN DISTRICT OF NEW YORK -------------------------------------------------------x KATHALEEN FREEMAN, et al., Plaintiffs, MEMORANDUM & ORDER 18-CV-7359 (PKC) (CLP) - against - 19-CV-2146 (PKC) (CLP) HSBC HOLDINGS PLC, HSBC BANK PLC, HSBC BANK MIDDLE EAST LIMITED, HSBC BANK USA, N.A., BARCLAYS BANK PLC, STANDARD CHARTERED BANK, ROYAL BANK OF SCOTLAND, N.V., CREDIT SUISSE AG, BANK SADERAT PLC, COMMERZBANK AG, and JOHN DOES 1–50, Defendants. -------------------------------------------------------x RYAN BOWMAN, et al., Plaintiffs, - against - HSBC HOLDINGS PLC, HSBC BANK PLC, HSBC BANK MIDDLE EAST LIMITED, HSBC BANK USA, N.A., BARCLAYS BANK PLC, STANDARD CHARTERED BANK, ROYAL BANK OF SCOTLAND, N.V., CREDIT SUISSE AG, BANK SADERAT PLC, COMMERZBANK AG, and JOHN DOES 1–50, Defendants. -------------------------------------------------------x PAMELA K. CHEN, United States District Judge: In November 2014, a group of American citizens killed or injured by terrorist attacks in Iraq between 2004 and 2011, and/or their families, filed an action, Freeman, et al. v. HSBC Holdings PLC, et al., 14-CV-6601 (PKC) (CLP) (“Freeman I”), against ten banking institutions— HSBC Holdings, PLC, HSBC Bank PLC, HSBC Bank Middle East Ltd., and HSBC Bank USA, 1 Case 1:18-cv-07359-PKC-CLP Document 90 Filed 01/07/21 Page 2 of 21 PageID #: <pageID> N.A. (the “HSBC Defendants”); Barclays Bank PLC; Standard Chartered Bank; Royal Bank of Scotland, N.V.; Credit Suisse AG; Bank Saderat PLC (“Bank Saderat”)1; and Commerzbank AG (“Commerzbank”)—as well as John Does 1–50, seeking damages pursuant to the Antiterrorism Act (the “ATA”), 18 U.S.C. -
Notice of Annual General Meeting to Be Held on 22 May 2009
THIS DOCUMENT IS IMPORTANT AND REQUIRES YOUR IMMEDIATE ATTENTION. If you are in any doubt as to any aspect of the proposals referred to in this document or as to the action you should take, you should consult a stockbroker, solicitor, accountant or other appropriate independent professional adviser. If you have sold or transferred all your shares in HSBC Holdings plc (the “Company”), you should at once forward this document and the accompanying Form of Proxy to the stockbroker, bank or other agent through whom the sale or transfer was effected for transmission to the purchaser or transferee. This document should be read in conjunction with the Annual Report and Accounts and/or Annual Review in respect of the year ended 31 December 2008. Hong Kong Exchanges and Clearing Limited and The Stock Exchange of Hong Kong Limited take no responsibility for the contents of this document, make no representation as to its accuracy or completeness and expressly disclaim any liability whatsoever for any loss howsoever arising from or in reliance upon the whole or any part of the contents of this document. The ordinary shares of HSBC Holdings plc trade under stock code 5 on The Stock Exchange of Hong Kong Limited. Shareholders may at any time choose to receive corporate communications in printed form or to receive notifications of their availability on HSBC’s website. To receive future notifications of the availability of corporate communications on HSBC’s website by email, or revoke or amend an instruction to receive such notifications by email, go to www.hsbc.com/ecomms. -
Refreshing the Biologic Pipeline 2020
news feature Credit: Science Lab / Alamy Stock Photo Refreshing the biologic pipeline 2020 In the absence of face-to-face meetings, FDA and industry implemented regulatory workarounds to maintain drug and biologics approvals. These could be here to stay. John Hodgson OVID-19 might have been expected since 1996) — a small miracle in itself “COVID-19 confronted us with the need to severely impair drug approvals (Fig. 1 and Table 1). to better triage sponsors’ questions,” says Cin 2020. In the event, however, To the usual crop of rare disease and Peter Marks, the director of the Center for industry and regulators delivered a small genetic-niche cancer treatments, 2020 Biologics Evaluation and Research (CBER) miracle. They found workarounds and also added a chimeric antigen receptor at the FDA. “That was perhaps the single surrogate methods of engagement. Starting (CAR)-T cell therapy with a cleaner biggest takeaway from the pandemic related in January 2020, when the outbreak veered manufacturing process and the first to product applications.” Marks says that it westward, the number of face-to face approved blockbuster indication for a became very apparent with some COVID- meetings declined rapidly; by March, small-interfering RNA (siRNA) — the 19-related files that resolving a single they were replaced by Webex and Teams. European Medicines Agency’s (EMA) issue can help a sponsor enormously and (Secure Zoom meeting are to be added registration of the RNA interference accelerate the development cycle. Before this year.) And remarkably, by 31 December, (RNAi) therapy Leqvio (inclisiran) for COVID-19, it was conceivable that a small the US Food and Drug Administration cardiovascular disease. -
7521821181.Pdf
Before the FEDERAL COMMUNICATIONS COMMISSION Washington, DC 20554 In the Matter of ) ) Comcast Corporation, Time Warner Cable Inc., ) MB Docket No. 14-57 Charter Communications, Inc., And Spinco To ) Assign And Transfer Control Of FCC Licenses ) And Other Authorizations ) COMMENTS OF RFD-TV Patrick Gottsch RFD-TV c/o Rural Media Group, Inc. 9500 West Dodge Road Suite 101 Omaha, NE 68114 (402) 991-6290 August 25, 2014 TABLE OF CONTENTS Page I. INTRODUCTION ......................................................................................................1 II. BACKGROUND .........................................................................................................2 III. THE FCC SHOULD ENSURE THAT A POST-MERGER COMCAST DOES NOT DISCRIMINATE AGAINST RFD-TV'S INDEPENDENT RURAL PROGRAMMING.......................................................................................4 IV. RFD-TV VIEWERS STRONGLY SUPPORT REINSTATING AND EXPANDING CARRIAGE OF RFD-TV POST-MERGER ............................... 11 V. PROPOSED MERGER CONDITIONS .................................................................12 VI. CONCLUSION. ........................................................................................................14 i Before the FEDERAL COMMUNICATIONS COMMISSION Washington, DC 20554 In the Matter of ) ) Comcast Corporation, Time Warner Cable Inc., ) MB Docket No. 14-57 Charter Communications, Inc., And Spinco To ) Assign And Transfer Control Of FCC Licenses ) And Other Authorizations ) COMMENTS OF RFD-TV I. INTRODUCTION On April -
Chapter 11 ) INTELSAT
Case 20-32299-KLP Doc 495 Filed 07/09/20 Entered 07/09/20 15:11:39 Desc Main Document Page 1 of 16 IN THE UNITED STATES BANKRUPTCY COURT FOR THE EASTERN DISTRICT OF VIRGINIA RICHMOND DIVISION ) In re: ) Chapter 11 ) 1 INTELSAT S.A., et al., ) Case No. 20-32299 (KLP) ) Debtors. ) (Jointly Administered) ) DECLARATION OF DISINTERESTEDNESS OF HOGAN LOVELLS US LLP AS PROPOSED ORDINARY COURSE PROFESSIONAL I, Steven M. Kaufman, declare under penalty of perjury: 1. I am a Partner of Hogan Lovells US LLP, located at Columbia Square, 555 Thirteenth Street, NW, Washington, D.C. 2004 (“HLUS”). 2. Intelsat S.A. and its affiliates, as debtors and debtors in possession (collectively, the “Debtors”), have requested that HLUS continue to provide legal services to the Debtors as an ordinary course professional pursuant to section 327(e) of the Bankruptcy Code in the Debtors’ chapter 11 cases (collectively, the “Chapter 11 Cases”), and HLUS has agreed to provide such services. Such services may be provided by HLUS directly and/or through its affiliated businesses, including Hogan Lovells International LLP (collectively, the “Firm”), through arrangements with HLUS. 3. The Firm may have performed services in the past, may currently perform services, and may perform services in the future in matters unrelated to the Chapter 11 Cases for persons or entities that are parties in interest in the Chapter 11 Cases. See Schedule A attached 1 Due to the large number of Debtors in these Chapter 11 Cases, for which joint administration has been granted, a complete list of the Debtor entities and the last four digits of their federal tax identification numbers is not provided herein. -
Market Measures
Market Measures 2,080 S&P 500 17,800 Dow Jones industrials 2,020 Close: 2,056.50 17,440 Close: 17,528.27 Change: -4.49 (-0.2%) Change: -23.90 (-0.1%) 1,960 10 DAYS 17,080 10 DAYS 2,160 18,400 2,080 17,600 2,000 16,800 1,920 16,000 1,840 15,200 JASOND JASOND Stocks Recap HIGH LOW CLOSE CHG. %CHG. YTD DOW 17536.90 17437.34 17528.27 -23.90 -0.14% -1.65% NYSE NASD DOW Trans. 7614.09 7508.65 7566.70 -55.91 -0.73% -17.21% DOW Util. 582.92 578.01 582.40 +1.38 +0.24% -5.77% Vol. (in mil.) 2,422 1,283 NYSE Comp. 10225.99 10169.09 10217.41 -41.14 -0.40% -5.74% Pvs. Volume 1,389 691 NASDAQ 5041.27 4999.07 5040.99 -7.50 -0.15% +6.44% Advanced 1202 1008 S&P 500 2056.76 2044.20 2056.50 -4.49 -0.22% -0.12% Declined 1926 1848 S&P 400 1413.95 1400.33 1413.86 -2.24 -0.16% -2.66% New Highs 53 43 Wilshire 5000 21354.56 21165.08 21296.18 -58.38 -0.27% -1.72% New Lows 24 54 Russell 2000 1153.98 1140.02 1148.21 -6.55 -0.57% -4.69% Metals & Season Season Commodities Exp. Vol High Low Settle Chg Exp. Vol High Low Settle Chg CORN WHEAT Jul 16 25,572 597.50 373 373.75 -3 Mar 16 58,552 769 465.50 466.50 -1 May 16 50,286 514.25 367 367.75 -3 Jul 16 13,082 732 480.50 481 -1.75 SILVER CLOSE CHANGE Mar 16 179,546 512 360.50 361 -3.50 May 16 14,614 765.75 473 473.25 -1.25 OATS CATTLE Handy & Harman 13.945 -0.455 May 16 60 333.75 220 224.25 +3.75 Feb 16 18,059 437.00 121.97 136.15 -.87 Jul 16 6 351.50 223.25 227.50 +3 Jun 16 7,120 328.25 115.47 127.10 -.35 CLOSE CHANGE GOLD Mar 16 688 350.50 215 223.75 +4.25 Apr 16 11,607 422.75 123.05 137.37 -.65 Handy & Harman 1070.60 -1.30 SOYBEANS HOGS Engelhard 1073.47 +1.10 Mar 16 180,566 1216.25 847 861.25 -11.75 Jun 16 1,108 758.75 70.25 78.55 +.95 Merc. -
Cox Communications, Inc
COX ARKANSAS TELCOM, L.L.C. ARKANSAS PSC TARIFF NO. 2 d/b/a Cox Communications d/b/a Cox Business Services ORIGINAL TITLE PAGE ACCESS SERVICES Specialized Common Carrier Service Regulations and Rates of COX ARKANSAS TELCOM, L.L.C. d/b/a Cox Communications d/b/a Cox Business Services This tariff includes the rates, charges, terms and conditions of service for the provision of intrastate common carrier telecommunications services by Cox Arkansas Telcom, L.L.C. d/b/a/ Cox Communications ("Cox") for originating and terminating End User’s and Customer’s calls within Arkansas. Issue Date: August 18, 2006 Effective Date: August 18, 2006 Issued by: Martin Corcoran Director, Tariff Development Cox Communications, Inc. 1400 Lake Hearn Drive, Atlanta, Georgia 30319 COX ARKANSAS TELCOM, L.L.C. ARKANSAS PSC TARIFF NO. 2 d/b/a/ Cox Communications d/b/a Cox Business Services EIGHT REVISED PAGE 1 ACCESS SERVICES CHECK SHEET All pages of this tariff are effective as of the date shown. Original and revised pages, as named below, comprise all changes from the original tariff in effect on the date indicated. PAGE REVISION PAGE REVISION PAGE REVISION Title Page Original 31 Original 60* 1st Revised 1* 8th Revised 32 Original 61* 1st Revised 2 Original 33 Original 62* 1st Revised 3* 1st Revised 34 Original 63 Original 4 Original 35 Original 64 Original 5 Original 36* 1st Revised 65 Original 6 Original 37* 1st Revised 66 Original 7 Original 38* 1st Revised 67 Original 8 Original 39* 1st Revised 68 Original 9 Original 40* 1st Revised 69 Original 10 Original 41* -
SCHEDULE of INVESTMENTS MID-CAP 1.5X STRATEGY FUND
SCHEDULE OF INVESTMENTS December 31, 2020 MID-CAP 1.5x STRATEGY FUND SHARES VALUE SHARES VALUE COMMON STOCKS† - 39.5% United Bankshares, Inc. 118 $ 3,823 Kinsale Capital Group, Inc. 19 3,802 FINANCIAL - 9.3% Highwoods Properties, Inc. REIT 95 3,765 Medical Properties Trust, Inc. REIT 489 $ 10,655 RLI Corp. 36 3,749 Brown & Brown, Inc. 215 10,193 Park Hotels & Resorts, Inc. REIT 215 3,687 Camden Property Trust REIT 89 8,893 Selective Insurance Group, Inc. 55 3,684 CyrusOne, Inc. REIT 110 8,047 Rayonier, Inc. REIT 125 3,673 Alleghany Corp. 13 7,848 Healthcare Realty Trust, Inc. REIT 124 3,670 RenaissanceRe Holdings Ltd. 46 7,628 Valley National Bancorp 369 3,598 Omega Healthcare Investors, Inc. REIT 207 7,518 Webster Financial Corp. 82 3,456 STORE Capital Corp. REIT 216 7,340 Bank OZK 110 3,440 Reinsurance Group of Physicians Realty Trust REIT 190 3,382 America, Inc. — Class A 62 7,186 PROG Holdings, Inc. 62 3,340 Eaton Vance Corp. 104 7,065 Hudson Pacific Properties, Inc. REIT 139 3,339 Jones Lang LaSalle, Inc.* 47 6,973 Sabra Health Care REIT, Inc. 189 3,283 Signature Bank 49 6,629 Alliance Data Systems Corp. 44 3,260 Lamar Advertising Co. — Class A REIT 79 6,574 Wintrust Financial Corp. 53 3,238 East West Bancorp, Inc. 129 6,541 CIT Group, Inc. 90 3,231 National Retail Properties, Inc. REIT 159 6,506 JBG SMITH Properties REIT 102 3,190 First Horizon National Corp. 507 6,469 Sterling Bancorp 177 3,183 SEI Investments Co. -
VIRTUS ZEVENBERGEN INNOVATIVE GROWTH STOCK FUND SCHEDULE of INVESTMENTS (Unaudited) MARCH 31, 2021
VIRTUS ZEVENBERGEN INNOVATIVE GROWTH STOCK FUND SCHEDULE OF INVESTMENTS (Unaudited) MARCH 31, 2021 ($ reported in thousands) Shares Value Shares Value Footnote Legend: (1) Non-income producing. COMMON STOCKS—99.0% Industrials—3.9% Communication Services—9.3% Desktop Metal, Inc. (1) Country Weightings† Coursera, Inc.(1) 7,100 $ 320 Class A 359,800 $ 5,361 (1) Uber Technologies, United States 87% Netflix, Inc. 84,500 44,080 (1) Snap, Inc. Class A(1) 586,650 30,676 Inc. 897,900 48,944 Canada 7 Zillow Group, Inc. 54,305 Brazil 5 Class C(1) 434,335 56,307 Israel 1 Information Technology—43.9% Total 100% 131,383 (1) Coupa Software, Inc. 78,450 19,964 † (1) % of total investments as of March 31, 2021. Consumer Discretionary—25.3% fuboTV, Inc. 315,350 6,976 (1) NVIDIA Corp. 107,000 57,131 Airbnb, Inc. Class A 91,100 17,121 (1) Amazon.com, Inc.(1) 15,200 47,030 Okta, Inc. 235,575 51,928 (1) Paylocity Holding Chegg, Inc. 322,325 27,610 (1) (1) Corp. 110,750 19,916 Chewy, Inc. Class A 340,400 28,835 (1) Fiverr International PayPal Holdings, Inc. 198,850 48,289 Ltd.(1) 27,650 6,005 QUALCOMM, Inc. 204,050 27,055 RingCentral, Inc. Lululemon Athletica, (1) (1) Class A 129,800 38,665 Inc. 41,690 12,787 (1) (1) ServiceNow, Inc. 78,325 39,171 MercadoLibre, Inc. 48,225 70,994 (1) Peloton Interactive, Inc. Shopify, Inc. Class A 78,200 86,528 (1) Snowflake, Inc. Class A 336,850 37,876 (1) Tesla, Inc.(1) 162,740 108,699 Class A 110,700 25,381 Sprout Social, Inc. -
February 4, 2020 - Public Issue
February 4, 2020 - Public Issue KEY DEVELOPMENTS ACA Connects Commends FCC On Adopting RDOF To Advance Rural Broadband Deployment In A Cost-Efficient Manner ACA Connects President and CEO Matthew M. Polka issued the following statement on Jan. 30 commending the Federal Communications Commission on adoption of the Rural Digital Opportunity Fund (RDOF): “Over the past decade, the FCC has made great progress in evolving its high-cost universal service programs so that existing providers are not overbuilt and funds are awarded more cost-effectively to providers offering higher- performance broadband service. Today’s adoption of the Rural Digital Opportunity Fund by the FCC is a significant step in that evolution. “By adopting a challenge process to ensure eligible areas are unserved and by using the ‘budget clearing round’ approach to awarding funds in the auction, the FCC will further ensure that residents and businesses at millions of unserved locations receive broadband service that is reasonably comparable to the service urban consumers receive. ACA Connects commends the Chairman and Commissioners for adopting this sound and forward-looking approach and instituting the new program.” ACA Connects Applauds FCC For Allowing Cable Operators To Email Required Notices To TV Stations ACA Connects President and CEO Matthew M. Polka issued the following statement on Jan. 30 applauding the FCC for allowing cable operators to use email to transmit required notices to TV stations: “ACA Connects applauds the FCC for adopting a Report and Order that will allow cable operators to send required notices to broadcasters by email rather than certified mail. This transition to email delivery will reduce administrative burdens and environmental waste while ensuring that notices are still timely received.