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European Union Risk Assessment Report 2-Eth European Chemicals Bureau Institute for Health and Consumer Protection European Union Risk Assessment Report European Chemicals Bureau CAS No: 103-11-7 EINECS No: 203-080-7 Existing Substances 2-ethylhexyl acrylate European 2-eth Union Risk Assessment Report Report Assessment Risk Union y lhex y l acr O y late O CAS: EC: 203-080-7 103-11-7 1st Priority List Volume: 61 EUR 21641 EN PL-1 61 European Union Risk Assessment Report 2-ETHYLHEXYL ACRYLATE CAS No: 103-11-7 EINECS No: 203-080-7 RISK ASSESSMENT LEGAL NOTICE Neither the European Commission nor any person acting on behalf of the Commission is responsible for the use which might be made of the following information A great deal of additional information on the European Union is available on the Internet. It can be accessed through the Europa Server (http://europa.eu.int). Cataloguing data can be found at the end of this publication Luxembourg: Office for Official Publications of the European Communities, 2005 © European Communities, 2005 Reproduction is authorised provided the source is acknowledged. Printed in Italy 2-ETHYLHEXYL ACRYLATE CAS No: 103-11-7 EINECS No: 203-080-7 RISK ASSESSMENT Final Report, 2005 Germany The risk assessment of 2-ethylhexyl acrylate has been prepared by Germany on behalf of the European Union. Contact point: Bundesanstalt für Arbeitsschutz und Arbeitsmedizin (BAuA) Anmeldestelle Chemikaliengesetz (Federal Institute for Occupational Safety and Health Notification Unit) Friedrich-Henkel-Weg 1-25 44149 Dortmund Fax: +49 (231) 9071 679 e-mail: [email protected] Date of Last Literature Search: 2003 Review of report by MS Technical Experts finalised: 2002 Final report: 2005 Foreword We are pleased to present this Risk Assessment Report which is the result of in-depth work carried out by experts in one Member State, working in co-operation with their counterparts in the other Member States, the Commission Services, Industry and public interest groups. The Risk Assessment was carried out in accordance with Council Regulation (EEC) 793/931 on the evaluation and control of the risks of “existing” substances. “Existing” substances are chemical substances in use within the European Community before September 1981 and listed in the European Inventory of Existing Commercial Chemical Substances. Regulation 793/93 provides a systematic framework for the evaluation of the risks to human health and the environment of these substances if they are produced or imported into the Community in volumes above 10 tonnes per year. There are four overall stages in the Regulation for reducing the risks: data collection, priority setting, risk assessment and risk reduction. Data provided by Industry are used by Member States and the Commission services to determine the priority of the substances which need to be assessed. For each substance on a priority list, a Member State volunteers to act as “Rapporteur”, undertaking the in-depth Risk Assessment and recommending a strategy to limit the risks of exposure to the substance, if necessary. The methods for carrying out an in-depth Risk Assessment at Community level are laid down in Commission Regulation (EC) 1488/942, which is supported by a technical guidance document3. Normally, the “Rapporteur” and individual companies producing, importing and/or using the chemicals work closely together to develop a draft Risk Assessment Report, which is then presented at a Meeting of Member State technical experts for endorsement. The Risk Assessment Report is then peer-reviewed by the Scientific Committee on Health and Environmental Risks (SCHER) which gives its opinion to the European Commission on the quality of the risk assessment. If a Risk Assessment Report concludes that measures to reduce the risks of exposure to the substances are needed, beyond any measures which may already be in place, the next step in the process is for the “Rapporteur” to develop a proposal for a strategy to limit those risks. The Risk Assessment Report is also presented to the Organisation for Economic Co-operation and Development as a contribution to the Chapter 19, Agenda 21 goals for evaluating chemicals, agreed at the United Nations Conference on Environment and Development, held in Rio de Janeiro in 1992. This Risk Assessment improves our knowledge about the risks to human health and the environment from exposure to chemicals. We hope you will agree that the results of this in-depth study and intensive co-operation will make a worthwhile contribution to the Community objective of reducing the overall risks from exposure to chemicals 1 O.J. No L 084, 05/04/1993 p.0001 – 0075 2 O.J. No L 161, 29/06/1994 p. 0003 – 0011 3 Technical Guidance Document, Part I – V, ISBN 92-827-801 [1234] V 0 OVERALL RESULTS OF THE RISK ASSESSMENT CAS No: 103-11-7 EINECS No: 203-080-7 IUPAC Name: 2-ethylhexyl acrylate Environment Conclusion (ii) There is at present no need for further information and/or testing and for risk reduction measures beyond those which are being applied already. 2-ethylhexyl acrylate represents, based on the present data configuration, no risk to the environment. There is therefore at present no need for further testing or gathering of exposure information. Human Health Workers Conclusion (iii) There is a need for limiting the risks; risk reduction measures which are already being applied shall be taken into account. The risk assessment reveals concern with regard to local effects after repeated inhalation for the formulation of preparations (Scenario 2). Skin sensitisation gives rise to concern for dermal exposure during production and polymerisation (Scenario 1), the formulation of preparations (Scenario 2) and the use of formulations containing monomeric 2-EHA in the building trade (Scenario 3) Human Health (toxicity) Consumers Conclusion (ii) There is at present no need for further information and/or testing and for risk reduction measures beyond those which are being applied already. Humans exposed via the environment Conclusion (ii) There is at present no need for further information and/or testing and for risk reduction measures beyond those which are being applied already. Human Health (risks from physico-chemical properties) Conclusion (ii) There is at present no need for further information and/or testing and for risk reduction measures beyond those which are being applied already. VI CONTENTS 1 GENERAL SUBSTANCE INFORMATION.......................................................................................... 4 1.1 IDENTIFICATION OF THE SUBSTANCE.................................................................................. 4 1.2 PURITY/IMPURITIES, ADDITIVES............................................................................................ 4 1.3 CLASSIFICATION .......................................................................................................................... 6 2 GENERAL INFORMATION ON EXPOSURE..................................................................................... 7 2.1 USE..................................................................................................................................................... 7 3 ENVIRONMENT ...................................................................................................................................... 9 3.1 ENVIRONMENTAL EXPOSURE.................................................................................................. 9 3.1.1 General discussion................................................................................................................... 9 3.1.1.1 Release into the environment..................................................................................... 9 3.1.1.2 Degradation ............................................................................................................... 9 3.1.1.3 Distribution................................................................................................................ 11 3.1.1.4 Accumulation............................................................................................................. 12 3.1.2 Aquatic compartment............................................................................................................... 12 3.1.2.1 Estimation of PEClocal/Generic approach: production and processing .................... 12 3.1.2.2 Estimation of PEClocal / Site-specific approach: production and processing ........... 12 3.1.2.3 Estimation of PEClocal/Generic approach: use......................................................... 13 3.1.2.4 Monitoring data ......................................................................................................... 14 3.1.2.5 Sediment.................................................................................................................... 14 3.1.3 Atmosphere.............................................................................................................................. 14 3.1.3.1 Estimation of PEClocal at production and processing............................................... 14 3.1.4 Terrestrial compartment........................................................................................................... 15 3.1.5 Non compartment specific exposure relevant to the food chain .............................................. 15 3.1.5.1 Secondary poisoning.................................................................................................. 15 3.1.6 Regional concentrations..........................................................................................................
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