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Rabbit Anti-C1orf84 /FITC Conjugated antibody

SL15077R-FITC

Product Name: Anti-C1orf84 /FITC Chinese Name: FITC标记的1号染色体开放阅读框84抗体 1 open reading frame 84; Hypothetical LOC149469; Alias: Uncharacterized protein C1orf84; SZT2_HUMAN. Organism Species: Rabbit Clonality: Polyclonal React Species: Human,Mouse,Rat,Dog,Cow,Horse,Rabbit,Sheep, ICC=1:50-200IF=1:50-200 Applications: not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. Molecular weight: 378kDa Form: Lyophilized or Liquid Concentration: 1mg/ml immunogen: KLH conjugated synthetic peptide derived from human C1orf84 Lsotype: IgG Purification: affinity purified by Protein A Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storewww.sunlongbiotech.com at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year Storage: when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. background: SZT2 (seizure threshold 2 homolog (mouse)), also known as SZT2A or SZT2B, is a 3,432 amino acid peroxisomal protein that plays a role in resistance to oxidative stress. Predominantly expressed in the parietal and frontal cortex, as well as in dorsal root Product Detail: ganglia of the brain, SZT2 is implicated in activity and the neuroprotection in peroxisomes. Existing as four alternatively spliced isoforms, SZT2 is thought to enhance epileptogenesis and is encoded by a that maps to human chromosome 1p34.2. Human spans 260 million base pairs, contains over 3,000 , comprises nearly 8% of the and houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome.

Function: Involved in oxidative stress. May be involved in superoxide dismutase activity and in neuroprotective effect of peroxisomes, but has no direct dismutase activity when tested in yeast. May enhance epileptogenesis and confer low seizure threshold (By similarity).

Subcellular Location: Peroxisome (By similarity).

Tissue Specificity: Expressed in the brain, predominantly in the parietal and frontal cortex as well as in dorsal root ganglia.

Database links: UniProtKB/Swiss-Prot: Q5T011.3

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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