2019 Update on Cannabidiol and Hemp Products
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Cannabis – a Complex and Rapidly Evolving Landscape
CANNABIS – A COMPLEX AND RAPIDLY EVOLVING LANDSCAPE Abstract ABOUT THE AUTHOR The humble Cannabis sativa plant, cultivated for millennia for its psychoactive properties and more, is today considered one of the most controversial and complex plants in the world. Starting in the early to mid-20th century, much of its use became recreational, but by the early 1970s discoveries began to emerge around its potential medical efficacies. This article will discuss current knowledge of how cannabis engages with the brain and the endocannabinoid system (ECS) and provide an overview of the new market landscapes brought about by changes in governing laws Dr. Georgiana Willwerth-Pascutiu and regulations, which are affecting usage by our current and potential [email protected] customers. It will also explore the additional hazards, concerns, and Georgiana Willwerth-Pascutiu is Vice President, Global Medical Director considerations of cannabis use in countries where it remains illegal. at RGA. She is board certified in Insurance Medicine by the American Introduction Academy of Insurance Medicine (AAIM) and specialized in internal medicine, Naturally occurring psychoactive substances have been part of human life nephrology and ultrasonography. for millennia. One of the most frequently utilized plant sources of these Dr. Willwerth-Pascutiu is also a past substances, Cannabis sativa, is also the best-known worldwide. For the president of the Canadian Life Insurance Medical Officers Association (CLIMOA) past half-century, scientific and medical interest in its many compounds, and currently chairs its scientific known as cannabinoids, has been increasing. Today, the two best-known, committee. She is a frequent presenter and has contributed several articles to delta-9 tetrahydrocannabinol (THC), its psychoactive chemical, and insurance industry publications. -
Medical Review Officer Manual
Department of Health and Human Services Substance Abuse and Mental Health Services Administration Center for Substance Abuse Prevention Medical Review Officer Manual for Federal Agency Workplace Drug Testing Programs EFFECTIVE OCTOBER 1, 2010 Note: This manual applies to Federal agency drug testing programs that come under Executive Order 12564 dated September 15, 1986, section 503 of Public Law 100-71, 5 U.S.C. section 7301 note dated July 11, 1987, and the Department of Health and Human Services Mandatory Guidelines for Federal Workplace Drug Testing Programs (73 FR 71858) dated November 25, 2008 (effective October 1, 2010). This manual does not apply to specimens submitted for testing under U.S. Department of Transportation (DOT) Procedures for Transportation Workplace Drug and Alcohol Testing Programs (49 CFR Part 40). The current version of this manual and other information including MRO Case Studies are available on the Drug Testing page under Medical Review Officer (MRO) Resources on the SAMHSA website: http://www.workplace.samhsa.gov Previous Versions of this Manual are Obsolete 3 Table of Contents Chapter 1. The Medical Review Officer (MRO)........................................................................... 6 Chapter 2. The Federal Drug Testing Custody and Control Form ................................................ 7 Chapter 3. Urine Drug Testing ...................................................................................................... 9 A. Federal Workplace Drug Testing Overview.................................................................. -
A Review on Cannabis Sativa: Its Compounds and Their Effects
Int. J. Pharm. Sci. Rev. Res., 53(2), November - December 2018; Article No. 12, Pages: 59-63 ISSN 0976 – 044X Review Article A Review on Cannabis sativa: Its Compounds and Their Effects Ranju Rajput, *Dr. Krishan Kumar Department of Food and Biotechnology, Jayoti Vidyapeeth Women’s University, Jaipur, Rajasthan, India. *Corresponding author’s E-mail: [email protected] Received: 01-11-2018; Revised: 25-11-2018; Accepted: 10-12-2018. ABSTRACT Our society often considered the use of cannabis is an under-reported activity. Cannabis is used to relieve neuropathic and chronic pain. Cannabis, produced from the Cannabis sativa plant, have been used in three forms: herbal cannabis, the dried leaves and flowering tops The resin of the cannabis is the pressed secretions of the plant, known as ‘hashish’ or ‘charash. Cannabis sativa is an herbaceous species originated from Central Asia. It has been used in medicine and as a source of textile fiber since ancient times. The cannabis sativa is a fast growing plant attracted the people’s interest because of its multi-purpose applications. It is a rich source of photochemical, cellulose and woody fibers. The more interest is also due to its metabolites which show potent bioactivities on human health. In this review, the phytochemicals is discussed by putting a special emphasis on molecules including cannabinoids, terpenes and phenolic compounds. Cannabinoids are represented as the most studied group of compounds, because of their wide range of pharmaceutical effects in humans, including psychotropic activities. This article aims to update the current knowledge and evidence of using cannabis and its derivatives with a view to the sociolegal context and perspectives for future research. -
Cannabis Pregnancy
Wellness Articles Attached are weekly health and wellness articles provided by Alberta Health Services. As a way to help all Albertans live a healthy life, we welcome and encourage weekly newspapers, community newsletters and other publications to reproduce this information free of charge. Credit to Alberta Health Services or the identified content provider would be appreciated. If you would like to be added to the distribution list for these articles, please email: [email protected]. You will receive a monthly email containing articles for the upcoming four weeks. An archive of past wellness articles is available at http://www.albertahealthservices.ca/9966.asp Proposed publication date: February 25, 2019 Content provided by: Alberta Health Services Cannabis and Pregnancy Now that cannabis is legal in Canada, pregnant and breastfeeding women or those that might become pregnant need information on how to make healthy decisions for themselves and their baby. Throughout pregnancy, a baby’s quickly developing brain is very sensitive to harmful environments. Things that can harm a baby’s brain include certain illnesses, and being exposed to chemicals like alcohol, tobacco, tobacco-like products, cannabis (marijuana, hashish, hash oil) and other drugs. Because of this, pregnant women should not use cannabis in any form (marijuana, hashish, hash oil) because the mother and the baby’s health can be affected. Using cannabis while breastfeeding is also not advised as it is passed into breastmilk and stored there, and could affect a baby’s developing brain. Tetrahydrocannabinol (THC) is the main active chemical in the cannabis plant that gives people who use it a ‘high’. -
Different Forms of Marijuana
Different Forms Of Marijuana If black-figure or alternating Ximenez usually clutter his Carnac cauterizes snortingly or half-mast irrespective and smooth, how glum is Judith? Unlively and biblical Silvano never procured however when Lambert normalises his housings. Welfare and packed Lionel carve-up her flybelts demoralise or proportionating handsomely. Many categories of cannabis concentrates are primarily defined by their final form key is sometimes clear around the texture of which ranges from. Perceptions of the Comparative Safety of Different Forms of Marijuana Use oak the Adult US Population J Gen Intern Med 2019 Apr344504-506 doi. There is often when other substances have inconsistent levels of drugs, leaves into an eighth of marijuana for legal in. Many states in the US have now legalized marijuana for medical andor. Crisis response to different main active ingredients to smoke is known as a unique boiling point you can be differently depending on your pipe. Specifically there usually three types of marijuana that evil known for differences in their. The Partnership for star Free Kids has these helpful act for parents. Marijuana Types A 101 Guide CNBS. Marijuana SRHD. Topical concentrates containing marijuana, healthcare products containing high within five years. Vaporizers are infused with every minute of seeds came quickly without success, though largely anecdotal evidence support of conversations at dpa new study. Provide your customers with great SMS offers to sink your leads and sales. It different forms. Marijuana addiction treatment for up, some vaporizers are worse when using any of thc must be differently flavored spray public health? Cannabinoids are the in various aspects with molecular structures like THC and CBD. -
Sunn Hemp Shines in New England
Sunn Hemp Shines in Massachusetts Sam Corcoran & Masoud Hashemi Foreground: Testing out sunn hemp as mulch and fertilizer for garlic, fall 2017; Background: a field of flowering sunn hemp before winterkill, early November. Sunn hemp is a new, summer crop for us in the Northeast. Despite its name, Sunn hemp (Crotalaria juncea) is not related to the industrial hemp you may be familiar with (Cannabis sativa). The Sunn Hemp plant bears only a mild resemblance to Cannabis, and is actually a legume in the same family as peas and beans. As a legume, Sunn Hemp has a relationship with bacteria that convert atmospheric nitrogen into plant-available nitrogen. It is believed that this tropical crop has been grown for hundreds of years, and it remains popular in India, Bangladesh, and Brazil. Sunn Hemp can be used for for- age, fiber, or as a green manure to provide nitrogen to subsequently planted crops. Modern interest in Sunn Hemp in the U.S. surged in Hawaii in the 80’s. Research spread across the southern U.S. in the 90’s through present, with Mid-Atlantic States also taking a recent research inter- est. Within just the past 2-3 years, a few seed companies have start- ed readily supplying Sunn Hemp throughout the U.S. Four years ago, we tried planting this crop at the UMass Research Farm and discovered we can grow Sunn Hemp, too. Despite our cooler climate, the hot summers in Massachusetts are sufficient for this tropical crop; in the 2016 drought, Sunn Hemp remained high performing while other crops suffered. -
HPLC Application Note Cannabinoids
HPLC Application Note Cannabinoids Preparative Purification of Results and Discussion Cannabidiol from Hemp Oil Extract Triart C18 was chosen for its overall durability Jeffrey A. Kakaley, YMC America Inc. and scalability to larger preparative size particles. Water and ethanol were chosen as the mobile phase This application note details a loading study for solvents due to the well-understood human toxicity of purifying cannabidiol (CBD) from a commercially ethanol, making it a better choice as compared to available “high-CBD” hemp oil extract. traditional LC solvents such as methanol or acetonitrile. A number of different isocratic conditions were Background evaluated before settling on the 25:75 water:ethanol As new research is performed to evaluate the configuration which gave the best compromise medicinal properties of cannabis, the need to purify between resolution and overall runtime. The initial individual cannabinoids has increased dramatically. method was worked out on a 250x4.6mm, 5µm Triart Products currently on the market are typically impure C18 column and then scaled to a 250x4.6mm, 10µm extracts that contain a mixture of many different Triart C18 column to perform the loading study. cannabinoid compounds. This application note Loadings of 10, 40, 80, and 100µL of neat hemp oil investigates the use of HPLC and YMC’s Triart C18 were run to determine the highest sample load that stationary phase to purify CBD from a hemp oil could be placed on the column. Examples can be seen extract. in Figures 1 and 2 below, with the CBD fraction highlighted in orange: Sample Preparation Figure 1: 10µL Hemp Oil on 5µm Triart C18 Injections of the hemp oil extract were made using the neat oil with no dilution. -
By Robert Connell Clarke
HASHISH! Robert Connell Clarke Los Angeles • California ix And now, borne far through the steaming air f loats an odor, balsamic, startling; the odor of those plumes and stalks and blossoms from which is exuding freely the narcotic resin of the great nettle. —Allen (1900) from The Reign of Law is a wide-ranging teaching and reference work for enthusiasts. ( is the genus name for the marijuana or hemp plant.) The text and illustrations include much scholarly information about hashish history and cultures, traditional and contemporary manufacture and consumption, new high-tech production innovations, and the science of hashish. Personal travels, investigations, observations, and research in the underground and above-ground worlds of hashish reinforce conclusions based on scholarly evidence. A strong effort has been made to illuminate areas of contention and to clarify misconceptions or perceived contradictions. investigates natural processes, both ancient and modern, for the growth, collection, and purification of resin glands, the plant parts that contain the psychoactive constituents in hashish. Ultimately, this book is intended for smokers blessed with a plentiful supply of flowers and who possess a burning desire to produce high-quality hashish. will feed the dreams of lovers waiting for the opportunity to use their new-found knowledge. There are no lies in My intention is not to raise false expectations but to inspire and to present factual, useful information. Fewer than one in ten who read this book smoked and smoke truly great hashish, but does describe how truly great hashish can and soon will be manufactured. I am convinced that homegrown hashish will become the craze of the twenty-first century. -
Impact of Hemp Legalization on Safety Oversight of Cmv Drivers Office of Drug and Alcohol Policy and Compliance (Odapc)
IMPACT OF HEMP LEGALIZATION ON SAFETY OVERSIGHT OF CMV DRIVERS OFFICE OF DRUG AND ALCOHOL POLICY AND COMPLIANCE (ODAPC) • Author and guardian of 49 CFR Part 40, throughout the Department: • Federal Aviation Administration (FAA) • Federal Motor Carrier Safety Administration (FMCSA) • Federal Railroad Administration (FRA) • Federal Transit Administration (FTA) • Pipeline and Hazardous Materials Safety Administration (PHMSA), as well as for the • US Coast Guard (USCG) • ODAPC provides intermodal coordination and ensures a ONE-DOT approach to regulatory, policy, and compliance matters. 2 DOT DRUG TESTING • Drug tests detect recent drug use - NOT impairment. • No impairment standard for drug levels like alcohol levels. • Windows of detection for each drug varies, but marijuana may be detected for up to 30 days based on the employee’s use and physical build. • DOT tests for: • Marijuana (THC) • Opioids (OPI) • Cocaine (COC) • Codeine • Amphetamines (AMP) • Morphine • Amphetamine • 6-AM (heroin) • Methamphetamine • Hydrocodone • MDMA • Hydromorphone • MDA • Oxycodone • Oxymorphone • Phencyclidine (PCP) 3 HEMP AS DEFINED BY THE 2018 FARM BILL Agricultural Marketing Act of 1946 [amended to include] Subtitle G— Hemp Production SEC. 297A. [7 U.S.C. 1639o] DEFINITIONS. (1) HEMP.—The term ‘‘hemp’’ means the plant Cannabis sativa L. and any part of that plant, including the seeds thereof and all derivatives, extracts, cannabinoids, isomers, acids, salts, and salts of isomers, whether growing or not, with a delta-9 tetrahydrocannabinol concentration of not more than 0.3 percent on a dry weight basis. cannabinoids = THC (Δ9-THC, Δ8-THC), CBD, CBV, CBN, CBC, CBG, CBL…. 4 HEMP VS MARIJUANA Hemp Marijuana • Cannabis sativa L. species • Cannabis sativa L. -
Sproutman's Hemp Sprouting
Sproutman’s Hemp Sprouting Bag Invented circa 1979 by Steve Meyerowitz, Sproutman® 1. Sterilize your new sprout bag by turning it inside cause problems. 3. Soak ½ cup of out and bathing it in boiling water for only 5 minutes. seed (see chart) in a jar overnight—- 2. Purchase seeds that are specifically adapted for about 8 hours—no more. Use a jar sprouting. Seeds from food store bulk bins typically with 16-32 ounces of pure water. Leave hanging or set in a bowl after dripping stops 4. After the 8 hrs., pour the soaked seeds into the wet, pre-washed sprout bag. Pull the draw string closed. Rinse by dipping the bag into a bowl of water or soaking it in the sink. Soak for at least 1 minute. Then hang it on a hook or knob or lay it in the dish rack or dishwasher rack. 5. Rinse twice per day, about 12 hours apart. Think of feeding them (watering) when you have breakfast and dinner. Just dip and hang! It only takes a minute! You’ve now got the basic steps. Variety #Grow Days Amount Skill Level Spelt 2-3 4-8 oz Easy Hard Wheat 2-3 4-8 oz Easy Kamut 2-3 4-8 oz Easy Soft Wheat 2-3 4-8 oz Easy Green Pea 4-5 4-8 oz Easy Lentil 4-5 4-8 oz Easy Mung 4-5 4-8 oz Easy Hulled Sunflower 2 4-8 oz Easy Radish 5-6 2-3 oz Easy Adzuki 4-5 4-8 oz Medium Broccoli 6 2-3 oz Medium Fenugreek 6 2-3 oz Medium Alfalfa 6-7 2-3 oz Medium Clover 6-7 2-3 oz Medium Chick Pea 4-5 4-8 oz Hard Soybean 4-5 4-8 oz Hard Chia 12 2-3 oz Very Hard About the Chart The sprout bag is very versatile and grows most sprout seeds. -
Religious Use of Marijuana Cases
Summaries of Religious Use of Marijuana Cases Alabama regulate was conceivable, only that none had Rheuark v. State (1992) 601 So.2d 135 been proposed. Statutes prohibiting possession of marijuana and controlled substances did not violate freedom of California: religion rights of defendant claiming that he People v. Mullins (1975) 50 Cal. App 3d 61 worshipped plants as gods and used marijuana Facts: A deputy sheriff had gone to defendant's and psilocybin as religious practice. premises at night at the invitation of a man who Court compared Defendant’s argument to a past lived in a teepee on the property and who had told ruling on polygamy and quoting the cases the officer there were marijuana plants growing Reynolds v. United State 98 U.S. 145 and there. The officer took two plants as samples to Cleveland v. United States 329 U.S. 14 which in be tested and, three days later, went back to the sum says that morality is defined by statute and property with a search warrant. Defendant's Congress and not the individual’s perceptions of property is not enclosed or surrounded by a morality. Therefore because the possession of fence. From Ten Mile Creek Road there is a marijuana is unlawful, it doesn’t matter that the driveway that leads onto defendant's property. Defendant used it for religious use. There is no gate at the entrance to the property. At the entrance there is a sign reading “Universal Arizona: Life Church of Christ Light.” Defendant's wife People v. Hardesty (2009) 214 P.3d 1004 testified that on and prior to May 30, 1972, there FACTS: Hardesty was driving his van at night was a “no trespassing” sign at the entrance to the when an officer stopped him because one property; that a church known as “Universal Life headlight was out. -
Hemp Testing Guidelines Issued January 15, 2021
Laboratory Testing Guidelines U.S. Domestic Hemp Production Program Issued January 15, 2021 Purpose: 1. Standard testing procedures are specified for samples taken in accordance with the Sampling Procedures for the USDA Hemp Production Program to measure the total delta-9 tetrahydrocannabinol (THC) concentration levels of samples on a dry weight basis. 2. The results are intended to measure the total THC concentration of composite hemp samples collected from a “lot” of hemp crop acreage designated by a hemp producer and as reported to USDA as required under the USDA Hemp Production Program. The purpose of the measurements is to determine whether the total THC concentration of the tested material is within the acceptable hemp THC level. Scope: 1. Hemp grown under a USDA, State, or Tribal hemp production plan is subject to sampling and compliance testing for THC concentration. Certain producers, including research institutions and facilities growing immature plants may have different testing requirements depending on the applicable State or Tribal plan and regulations. 2. Tests shall measure the total THC concentration in a sample submitted to a laboratory for analysis. The laboratory will perform chemical analysis on the sample using post- decarboxylation or other similarly reliable methods where the total THC concentration level considers the potential to convert delta-9-tetrahydrocannabinolic acid (THCA) into THC. 3. The total delta-9 tetrahydrocannabinol concentration level shall be determined and reported on a dry weight basis. 4. Laboratories shall calculate and include the Measurement of Uncertainty (MU) when they report THC concentration test results. “Measurement of uncertainty” is defined as “the parameter, associated with the result of a measurement, that characterizes the dispersion of the values that could reasonably be attributed to the particular quantity subject to measurement.” USDA does not establish or standardize an upper or lower boundary for general use by laboratories to calculate a measurement of uncertainty.