International Standards for the Treatment of Drug Use Disorders
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Neonatal Drug Withdrawal Abstract
Guidance for the Clinician in Rendering Pediatric Care CLINICAL REPORT Neonatal Drug Withdrawal Mark L. Hudak, MD, Rosemarie C. Tan, MD,, PhD, THE abstract COMMITTEE ON DRUGS, and THE COMMITTEE ON FETUS AND Maternal use of certain drugs during pregnancy can result in transient NEWBORN neonatal signs consistent with withdrawal or acute toxicity or cause KEY WORDS opioid, methadone, heroin, fentanyl, benzodiazepine, cocaine, sustained signs consistent with a lasting drug effect. In addition, hos- methamphetamine, SSRI, drug withdrawal, neonate, abstinence pitalized infants who are treated with opioids or benzodiazepines to syndrome provide analgesia or sedation may be at risk for manifesting signs ABBREVIATIONS of withdrawal. This statement updates information about the clinical CNS—central nervous system — presentation of infants exposed to intrauterine drugs and the thera- DTO diluted tincture of opium ECMO—extracorporeal membrane oxygenation peutic options for treatment of withdrawal and is expanded to include FDA—Food and Drug Administration evidence-based approaches to the management of the hospitalized in- 5-HIAA—5-hydroxyindoleacetic acid fant who requires weaning from analgesics or sedatives. Pediatrics ICD-9—International Classification of Diseases, Ninth Revision — – NAS neonatal abstinence syndrome 2012;129:e540 e560 SSRI—selective serotonin reuptake inhibitor INTRODUCTION This document is copyrighted and is property of the American fi Academy of Pediatrics and its Board of Directors. All authors Use and abuse of drugs, alcohol, and tobacco contribute signi cantly have filed conflict of interest statements with the American to the health burden of society. The 2009 National Survey on Drug Use Academy of Pediatrics. Any conflicts have been resolved through and Health reported that recent (within the past month) use of illicit a process approved by the Board of Directors. -
Drug and Alcohol Withdrawal Clinical Practice Guidelines - NSW
Guideline Drug and Alcohol Withdrawal Clinical Practice Guidelines - NSW Summary To provide the most up-to-date knowledge and current level of best practice for the treatment of withdrawal from alcohol and other drugs such as heroin, and other opioids, benzodiazepines, cannabis and psychostimulants. Document type Guideline Document number GL2008_011 Publication date 04 July 2008 Author branch Centre for Alcohol and Other Drugs Branch contact (02) 9424 5938 Review date 18 April 2018 Policy manual Not applicable File number 04/2766 Previous reference N/A Status Active Functional group Clinical/Patient Services - Pharmaceutical, Medical Treatment Population Health - Pharmaceutical Applies to Area Health Services/Chief Executive Governed Statutory Health Corporation, Board Governed Statutory Health Corporations, Affiliated Health Organisations, Affiliated Health Organisations - Declared Distributed to Public Health System, Ministry of Health, Public Hospitals Audience All groups of health care workers;particularly prescribers of opioid treatments Secretary, NSW Health Guideline Ministry of Health, NSW 73 Miller Street North Sydney NSW 2060 Locked Mail Bag 961 North Sydney NSW 2059 Telephone (02) 9391 9000 Fax (02) 9391 9101 http://www.health.nsw.gov.au/policies/ space space Drug and Alcohol Withdrawal Clinical Practice Guidelines - NSW space Document Number GL2008_011 Publication date 04-Jul-2008 Functional Sub group Clinical/ Patient Services - Pharmaceutical Clinical/ Patient Services - Medical Treatment Population Health - Pharmaceutical -
Substance Abuse and Dependence
9 Substance Abuse and Dependence CHAPTER CHAPTER OUTLINE CLASSIFICATION OF SUBSTANCE-RELATED THEORETICAL PERSPECTIVES 310–316 Residential Approaches DISORDERS 291–296 Biological Perspectives Psychodynamic Approaches Substance Abuse and Dependence Learning Perspectives Behavioral Approaches Addiction and Other Forms of Compulsive Cognitive Perspectives Relapse-Prevention Training Behavior Psychodynamic Perspectives SUMMING UP 325–326 Racial and Ethnic Differences in Substance Sociocultural Perspectives Use Disorders TREATMENT OF SUBSTANCE ABUSE Pathways to Drug Dependence AND DEPENDENCE 316–325 DRUGS OF ABUSE 296–310 Biological Approaches Depressants Culturally Sensitive Treatment Stimulants of Alcoholism Hallucinogens Nonprofessional Support Groups TRUTH or FICTION T❑ F❑ Heroin accounts for more deaths “Nothing and Nobody Comes Before than any other drug. (p. 291) T❑ F❑ You cannot be psychologically My Coke” dependent on a drug without also being She had just caught me with cocaine again after I had managed to convince her that physically dependent on it. (p. 295) I hadn’t used in over a month. Of course I had been tooting (snorting) almost every T❑ F❑ More teenagers and young adults die day, but I had managed to cover my tracks a little better than usual. So she said to from alcohol-related motor vehicle accidents me that I was going to have to make a choice—either cocaine or her. Before she than from any other cause. (p. 297) finished the sentence, I knew what was coming, so I told her to think carefully about what she was going to say. It was clear to me that there wasn’t a choice. I love my T❑ F❑ It is safe to let someone who has wife, but I’m not going to choose anything over cocaine. -
Running Head: PHARMACOLOGICAL TREATMENT for METHAMPHETAMINE
Running head: PHARMACOLOGICAL TREATMENT FOR METHAMPHETAMINE PHARMACOLOGICAL TREATMENT FOR METHAMPHETAMINE DEPENDENCE By BRINN CULVER A project submitted in partial fulfillment of the requirements for the degree of MASTER OF NURSING WASHINGTON STATE UNIVERSITY Department of Nursing APRIL 2014 PHARMACOLOGICAL TREATMENT FOR METHAMPHETAMINE ii To the Faculty of Washington State University: The members of the Committee appointed to examine the dissertation/thesis of BRINN CULVER find it satisfactory and recommend that it be accepted. Julie DeWitt-Kamada, DNP, ARNP, PMHNP Chair Anne Mason, DNP, ARNP, PMHNP Dawn Rondeau, DNP, ACNP, FNP PHARMACOLOGICAL TREATMENT FOR METHAMPHETAMINE iii PHARMACOLOGICAL TREATMENT FOR METHAMPHETAMINE DEPENDENCE Abstract By Brinn Culver Washington State University April 2014 Chair: Julie DeWitt-Kamada Methamphetamine (MA) is a highly addictive drug whose abuse causes widespread global consequences. The negative impact of MA use on individuals and communities warrants its consideration as a public health concern. MA has a complicated pharmacological action, and chronic use results in neurological dysfunction, including deficits in dopamine. Changes in dopaminergic function make treatment of MA dependence especially challenging, and the mainstay treatment of psychotherapy is insufficient in addressing dopamine deficit. Pharmacological treatments are being explored, but no medication has attained Federal Drug Administration approval, as it requires proof of achieving abstinence. From a harm reduction standpoint, several -
The ICD-10 Classification of Mental and Behavioural Disorders: Clinical Descriptions and Diagnostic Guidelines
The ICD-10 Classification of Mental and Behavioural Disorders: Clinical descriptions and diagnostic guidelines World Health Organization F10 - F19 Mental and behavioural disorders due to psychoactive substance use Overview of this block F10. – Mental and behavioural disorders due to use of alcohol F11. – Mental and behavioural disorders due to use of opioids F12. – Mental and behavioural disorders due to use of cannabinoids F13. – Mental and behavioural disorders due to use of sedative hypnotics F14. – Mental and behavioural disorders due to use of cocaine F15. – Mental and behavioural disorders due to use of other stimulants, including caffeine F16. – Mental and behavioural disorders due to use of hallucinogens F17. – Mental and behavioural disorders due to use of tobacco F18. – Mental and behavioural disorders due to use of volatile solvents F19. – Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances Four- and five-character codes may be used to specify the clinical conditions, as follows: F1x.0 Acute intoxication .00 Uncomplicated .01 With trauma or other bodily injury .02 With other medical complications .03 With delirium .04 With perceptual distortions .05 With coma .06 With convulsions .07 Pathological intoxication F1x.1 Harmful use F1x.2 Dependence syndrome .20 Currently abstinent .21 Currently abstinent, but in a protected environment .22 Currently on a clinically supervised maintenance or replacement regime [controlled dependence] .23 Currently abstinent, but receiving treatment with -
DEMAND REDUCTION a Glossary of Terms
UNITED NATIONS PUBLICATION Sales No. E.00.XI.9 ISBN: 92-1-148129-5 ACKNOWLEDGEMENTS This document was prepared by the: United Nations International Drug Control Programme (UNDCP), Vienna, Austria, in consultation with the Commonwealth of Health and Aged Care, Australia, and the informal international reference group. ii Contents Page Foreword . xi Demand reduction: A glossary of terms . 1 Abstinence . 1 Abuse . 1 Abuse liability . 2 Action research . 2 Addiction, addict . 2 Administration (method of) . 3 Adverse drug reaction . 4 Advice services . 4 Advocacy . 4 Agonist . 4 AIDS . 5 Al-Anon . 5 Alcohol . 5 Alcoholics Anonymous (AA) . 6 Alternatives to drug use . 6 Amfetamine . 6 Amotivational syndrome . 6 Amphetamine . 6 Amyl nitrate . 8 Analgesic . 8 iii Page Antagonist . 8 Anti-anxiety drug . 8 Antidepressant . 8 Backloading . 9 Bad trip . 9 Barbiturate . 9 Benzodiazepine . 10 Blood-borne virus . 10 Brief intervention . 11 Buprenorphine . 11 Caffeine . 12 Cannabis . 12 Chasing . 13 Cocaine . 13 Coca leaves . 14 Coca paste . 14 Cold turkey . 14 Community empowerment . 15 Co-morbidity . 15 Comprehensive Multidisciplinary Outline of Future Activities in Drug Abuse Control (CMO) . 15 Controlled substance . 15 Counselling and psychotherapy . 16 Court diversion . 16 Crash . 16 Cross-dependence . 17 Cross-tolerance . 17 Custody diversion . 17 Dance drug . 18 Decriminalization or depenalization . 18 Demand . 18 iv Page Demand reduction . 19 Dependence, dependence syndrome . 19 Dependence liability . 20 Depressant . 20 Designer drug . 20 Detoxification . 20 Diacetylmorphine/Diamorphine . 21 Diuretic . 21 Drug . 21 Drug abuse . 22 Drug abuse-related harm . 22 Drug abuse-related problem . 22 Drug policy . 23 Drug seeking . 23 Drug substitution . 23 Drug testing . 24 Drug use . -
Alcohol Dependence, Withdrawal, and Relapse
Alcohol Dependence, Withdrawal, and Relapse Howard C. Becker, Ph.D. Continued excessive alcohol consumption can lead to the development of dependence that is associated with a withdrawal syndrome when alcohol consumption is ceased or substantially reduced. This syndrome comprises physical signs as well as psychological symptoms that contribute to distress and psychological discomfort. For some people the fear of withdrawal symptoms may help perpetuate alcohol abuse; moreover, the presence of withdrawal symptoms may contribute to relapse after periods of abstinence. Withdrawal and relapse have been studied in both humans and animal models of alcoholism. Clinical studies demonstrated that alcoholdependent people are more sensitive to relapse provoking cues and stimuli than nondependent people, and similar observations have been made in animal models of alcohol dependence, withdrawal, and relapse. One factor contributing to relapse is withdrawalrelated anxiety, which likely reflects adaptive changes in the brain in response to continued alcohol exposure. These changes affect, for example, the body’s stress response system. The relationship between withdrawal, stress, and relapse also has implications for the treatment of alcoholic patients. Interestingly, animals with a history of alcohol dependence are more sensitive to certain medications that impact relapselike behavior than animals without such a history, suggesting that it may be possible to develop medications that specifically target excessive, uncontrollable alcohol consumption. KEY WORDS: Alcoholism; alcohol dependence; alcohol and other drug (AOD) effects and consequences; neuroadaptation; AOD withdrawal syndrome; AOD dependence relapse; pharmacotherapy; human studies; animal studies he development of alcohol expectations about the consequences of drinking (Koob and Le Moal 2008). dependence is a complex and alcohol use. -
Neurochemical Mechanisms Underlying Alcohol Withdrawal
Neurochemical Mechanisms Underlying Alcohol Withdrawal John Littleton, MD, Ph.D. More than 50 years ago, C.K. Himmelsbach first suggested that physiological mechanisms responsible for maintaining a stable state of equilibrium (i.e., homeostasis) in the patient’s body and brain are responsible for drug tolerance and the drug withdrawal syndrome. In the latter case, he suggested that the absence of the drug leaves these same homeostatic mechanisms exposed, leading to the withdrawal syndrome. This theory provides the framework for a majority of neurochemical investigations of the adaptations that occur in alcohol dependence and how these adaptations may precipitate withdrawal. This article examines the Himmelsbach theory and its application to alcohol withdrawal; reviews the animal models being used to study withdrawal; and looks at the postulated neuroadaptations in three systems—the gamma-aminobutyric acid (GABA) neurotransmitter system, the glutamate neurotransmitter system, and the calcium channel system that regulates various processes inside neurons. The role of these neuroadaptations in withdrawal and the clinical implications of this research also are considered. KEY WORDS: AOD withdrawal syndrome; neurochemistry; biochemical mechanism; AOD tolerance; brain; homeostasis; biological AOD dependence; biological AOD use; disorder theory; biological adaptation; animal model; GABA receptors; glutamate receptors; calcium channel; proteins; detoxification; brain damage; disease severity; AODD (alcohol and other drug dependence) relapse; literature review uring the past 25 years research- science models used to study with- of the reasons why advances in basic ers have made rapid progress drawal neurochemistry as well as a research have not yet been translated Din understanding the chemi- reluctance on the part of clinicians to into therapeutic gains and suggests cal activities that occur in the nervous consider new treatments. -
A. DSM-IV to ICD-9 Cross Walk
San Mateo County Mental Health Services DSM IV to ICD 9 Cross Walk for Diagnoses Requiring Clinician Decision Use this cross walk of DSM IV diagnosis to record the appropriate ICD 9 diagnosis. These diagnoses require the clinician to choose the appropriate ICD 9 diagnoses. All other cross walks of DSM IV to ICD 9 will be done automatically by MIS. Schizophrenia and Other Psychotic Disorders DSM IV Disorder ICD 9 Disorder 295.10 Schizophrenia Disorganized Type 295.1x Schizophrenic Disorders, Disorganized Type 295.20 Schizophrenia Catatonic Type 295.2x Schizophrenic Disorders, Catatonic Type 295.30 Schizophrenia Paranoid Type 295.3x Schizophrenic Disorders, Paranoid Type 295.40 Schizophreniform Disorder 295.4x Acute Schizophrenic Episode 295.60 Schizophrenia Residual Type 295.6x Schizophrenic Disorders, Residual Type 295.70 Schizoaffective Disorder 295.7x Schizo-Affective Type 295.90 Schizophrenia Undifferentiated Type 295.9x Schizophrenic Disorders, Undifferentiated Type The 5th digit for the ICD 9 Diagnosis for the above Schizophrenic disorders must be specified as follows: 0 Unspecified 3 Subchronic w/ Acute Exacerbation 1 Subchronic 4 Chronic w/ Acute Exacerbation 2 Chronic 5 in Remission Pervasive Developmental Disorders DSM IV Disorder ICD 9 Disorder 299.00 Autistic Disorder 299.0x Infantile Autism 299.10 Childhood Disintegrative Disorder 299.1x Childhood Disintegrative Disorder The 5th digit for the ICD 9 Diagnosis for the above Autistic disorders must be specified as follows: 0 Current or Active Status 1 Residual State Other Conditions That May Be A Focus of Clinical Attention V61.12 Physical Abuse of Adult (if by Partner) V61.11 Counseling for Victim of Spousal or Partner Abuse Sexual Abuse of Adult (if by Partner) V61.12 Counseling for Perpetrator of Spousal or Partner Abuse Inclusion of a diagnosis on this sheet does not imply the diagnosis is medically necessary for specialty mental health services. -
Parenting Children Who Have Been Exposed to Methamphetamine
Non-Return Information Packet Assisting families on their lifelong journey Parenting Children Who Have Been Exposed to Methamphetamine A Brief Guide for Adoptive, Guardianship, and Foster Parents Oregon Post Adoption Resource Center 2950 SE Stark Street, Suite 130 Portland, Oregon 97214 503-241-0799 800-764-8367 503-241-0925 Fax [email protected] www.orparc.org ORPARC is a contracted service of the Oregon Department of Human Services. Please do not reproduce without permission. PARENTING CHILDREN WHO HAVE BEEN EXPOSED TO METHAMPHETAMINE A BRIEF GUIDE FOR ADOPTIVE, GUARDIANSHIP AND FOSTER PARENTS Table of Contents Introduction: ............................................................................................................. 1 Part I: Methamphetamine: An Overview ........................................................... 2 What is meth? What are its effects on the user? How prevalent is meth use? How is meth addiction treated? Part II: Meth’s Effects on Children ...................................................................... 7 What are the prenatal effects of exposure? What are the postnatal effects of prenatal exposure? What are the environmental effects on children? Part III: Parenting Meth-Exposed Children ....................................................... 11 Guiding principles Age-specific suggestions Part IV: Reprinted Articles .................................................................................. 20 Appendix A: Recommended Resources Appendix B: Sources Page i PARENTING CHILDREN WHO HAVE -
Substance Abuse and Addictions Management
SUBSTANCE ABUSE AND ADDICTIONS MANAGEMENT Substance abuse , also known as drug abuse , is a patterned use of a substance (drug) in which the user consumes the substance in amounts or with methods neither approved nor supervised by medical professionals. Substance abuse/drug abuse is not limited to mood-altering or psycho-active drugs. If an activity is performed using the objects against the rules and policies of the matter (as in steroids for performance enhancement in sports), it is also called substance abused. Therefore, mood-altering and psychoactive substances are not the only types of drug abuse. Using illicit drugs – narcotics, stimulants, depressants (sedatives), hallucinogens, cannabis, even glues and paints, are also considered to be classified as drug/substance abuse. [2] Substance abuse often includes problems with impulse control and impulsive behaviour. The term "drug abuse" does not exclude dependency, but is otherwise used in a similar manner in nonmedical contexts. The terms have a huge range of definitions related to taking a psychoactive drug or performance enhancing drug for a non- therapeutic or non-medical effect. All of these definitions imply a negative judgment of the drug use in question (compare with the term responsible drug use for alternative views). Some of the drugs most often associated with this term include alcohol, amphetamines, barbiturates, benzodiazepines (particularly temazepam, nimetazepam, and flunitrazepam), cocaine, methaqualone, and opioids. Use of these drugs may lead to criminal penalty in addition to possible physical, social, and psychological harm, both strongly depending on local jurisdiction. [3] There are many cases in which criminal or antisocial behavior occur when the person is under the influence of a drug. -
Alcoholism and Chemical Substance Abuse Dependency 15 Unit Course
!1 Alcoholism and Chemical Substance Abuse Dependency Continuing Education Course (15 Hours/units) © 2019 by Aspira Continuing Education. All rights reserved. No part of this material may be transmitted or reproduced in any form, or by any means, mechanical or electronic without written permission of Aspira Continuing Education. Course Objectives: In addition to the course objectives listed, this course addresses the following content areas related to alcoholism and chemical substance abuse dependency: ✓ Counseling theory and practice ✓ Social and Cultural Foundations ✓ Assessment ✓ Professional practice issues ✓ Wellness and prevention ✓ Human growth and development Table of Contents: 1. Substance Use and Mental Health Indicators in the United States……….. 2 2. DSM-5 Diagnostic Summary…………………………………………….. 7 3. Types of Substance Abuse……………………………………………….. 11 4. Substance Abuse Treatment and Outcomes……………………………… 23 5. Substance Abuse Treatment for Clinicians………………………………. 33 6. Engaging Adolescents in Treatment……………………………………… 37 7. Brief Strategic Family Therapy for Adolescent Drug Abuse…………….. 45 8. Making the Connection: Trauma and Substance Abuse………………….. 86 9. Strategies for Working with Clients with Co-Occurring Disorders……… 93 10. HIV and Substance Abuse………………………………………………. 133 11. Sexually Transmitted Diseases and Substance Abuse…………………… 138 12. Substance Abuse and Domestic Violence……………………………….. 146 13. Substance Use and Mental Health Among College Students…………… 172 14. References………………………………………………………………. 176 !1 !2 1. Substance Use and Mental Health Indicators in the United States Summary The information below summarizes key findings from the 2018 National Survey on Drug Use and Health (NSDUH) for national indicators of substance use and mental health among people aged 12 or older in the civilian, non-institutionalized population of the United States. Results are provided for the overall category of people aged 12 or older and by age subgroups.