VAGINITIS, MONILIAL (Vaginal Yeast Infection)

Total Page:16

File Type:pdf, Size:1020Kb

VAGINITIS, MONILIAL (Vaginal Yeast Infection) VAGINITIS, MONILIAL (Vaginal Yeast Infection) BASIC INFORMATION • Avoid broad-spectrum antibiotics unless absolutely DESCRIPTION necessary. EXPECTED OUTCOMES Infection or inflammation of the vagina caused by a Usually curable with 2 weeks of treatment. Recurrence is yeast-like fungus (Monilia or Candida albicans). common. Monilial vaginitis causes at least 50% of infections in POSSIBLE COMPLICATIONS the vagina. Secondary bacterial infections of the vagina and other FREQUENT SIGNS AND SYMPTOMS pelvic organs. Severity of the following symptoms varies between TREATMENT women and from time to time in the same woman. GENERAL MEASURES • White, “curdy” vaginal discharge, (resembles • Diagnostic tests may include laboratory studies of lumps of cottage cheese). The odor may be vaginal discharge, Pap smear and pelvic examination. unpleasant, but not foul. • Drug therapy will be directed to the specific organism. • Swollen, red, tender, itching vaginal lips (labia) Your sexual partner may need treatment also. It is best and surrounding skin. not to do self-treatment for the disorder until the • Burning on urination. specific cause is determined. • Change in vaginal color from pale pink to red. • Don’t douche unless prescribed for you. CAUSES • If urinating causes burning, urinate through a tubular Monilia (or Candida) live in small numbers in a device, such as a toilet-paper roll or plastic cup with the healthy vagina, rectum and mouth. When the end cut out or pour a cup of warm water over the geni-tal vagina’s hormone and pH balance is disturbed, the area while you urinate. MEDICATIONS organisms multiply and cause infections. Monilial Your physician may recommend non-prescription anti- vaginitis tends to appear before menstrual periods fungal vaginal creams or suppositories. Keep creams or and subsides as soon as the period begins. Factors suppositories in the refrigerator. After treatment, you that may disturb the vagina’s balance include: may keep a refill of the medication so you can begin • Pregnancy. treatment quickly if the infection recurs. Follow the • Diabetes mellitus. directions carefully. Rarely, prescription medications • Antibiotic treatment. may be necessary. • Oral contraceptives. ACTIVITY • High carbohydrate intake, especially sugars and Avoid overexertion, heat and excessive sweating. Delay alcohol. sexual relations until symptoms cease. • Hot weather and/or non-ventilating clothing, which DIET increase moisture, warmth and darkness, fostering Increase consumption of yogurt, buttermilk or sour cream. fungal growth. Reduce alcohol and sugars. • Immunosuppression from drugs or disease. NOTIFY OUR OFFICE IF RISK INCREASES WITH • You or a family member has symptoms of monilial Factors listed under Causes. vaginitis. PREVENTIVE MEASURES • Despite treatment, symptoms worsen or persist longer • Keep genital area clean. Use plain unscented than 1 week. • Unusual vaginal bleeding or swelling develops. soap. • After treatment, symptoms recur. • Take showers rather than tub baths. • Wear cotton underpants or pantyhose with a Adapted from Instructions for Patients, Sixth Edition, H. Winter cotton crotch. Griffith, M.D., W.B Saunders Company. • Don’t sit around in wet clothing. • Avoid douches, vaginal deodorants and bubble baths. • Limit your intake of sweets and alcohol. • After urination or bowel movements, cleanse by wiping or washing from front to back (vagina to anus). • Lose weight if you are obese. • If you have diabetes, adhere to your treatment program. .
Recommended publications
  • Viamet Reports Positive Results from Interim Analysis of REVIVE Phase 2B Trial of VT-1161 in Recurrent Vulvovaginal Candidiasis
    Viamet Reports Positive Results from Interim Analysis of REVIVE Phase 2b Trial of VT-1161 in Recurrent Vulvovaginal Candidiasis -Interim Results Demonstrate Strong Clinical Benefit and Favorable Safety Profile- -Final Data Expected in Fourth Quarter of 2016- RESEARCH TRIANGLE PARK, N.C., March 9, 2016, – Viamet Pharmaceuticals, Inc. today reported positive results from a planned interim analysis of REVIVE (Recurrent Vulvovaginal Candidiasis Inhibition: an Oral VT-1161 Tablet Evaluation), its ongoing Phase 2b clinical trial of VT-1161 for the treatment of recurrent vulvovaginal candidiasis, or RVVC. RVVC is defined as three or more episodes of acute vulvovaginal candidiasis, or AVVC (commonly referred to as a vaginal yeast infection), in a 12-month period. VT-1161, the company’s lead product candidate, is a highly potent and selective, orally available inhibitor of fungal CYP51. “It is estimated that RVVC affects 5% to 8% of U.S. women during their child-bearing years and has a significant negative impact on quality of life,” commented Robert Schotzinger, M.D., Ph.D., CEO of Viamet. “Despite the number of women affected by this disease, we are not aware of any approved therapies for RVVC in the U.S. VT-1161 has demonstrated a high degree of potency against Candida species, the causative fungal pathogens responsible for RVVC, a robust oral pharmacokinetic profile, and a favorable safety profile in previous studies. These attributes, coupled with the positive interim results from our REVIVE trial, suggest that VT-1161 has the potential to be a highly effective treatment option for patients with RVVC.” REVIVE is a randomized, double-blind, placebo-controlled, 48-week clinical trial of VT-1161 in patients with RVVC.
    [Show full text]
  • Into Son," the Chief Replied
    THE SUNDAY OREGONJAN, PORTLAND, NOVEMBER 12, 1922 17 fcallet YOUTHFUL JAPANESE GIRL WHO IS VISITING IN PORTLAND we can get valiant assistance from the second alarm, who reproved a wings in her abbreviated every one of those who made the bystander who wanted to know skirts, there was a moment's horri- EPIDEMIC OF GRIME HAS FUTURE AS A VOCALIST. recent pilgrimage to the Evergreen NEW YORK THEATER FIRE why he seemed to take such a per- fied silence, followed by a storm state. sonal interest in saving the grimy of hisses. Before the dance ended structure. all'the women in the lower tier of Sporting Writers Suggested. EARLY-DA- Y with a fine RECALLS STAGE Old-Tim- Jeplous. boxes left the theater, CITY Here is the hunch. Oregon switching of hoopskirts, for this SWEEPS abounds in splendid fishing streams The chief smiled his wise smile: was in the year of grace, 1837. 01 and ideal hunting grounds for all Bowery Playhouse, Have Been "It'd be sort of hard for us rs They rang down the curtain on a game, virtually every Miners' Said to Cradle of American kinds of and Drama, Is Damaged. to see this place go. We bewildered and furious danseuse, one of the sporting editors of the are growing a little jealous of our was she permitted to dance New York papers is a "nut" on fish- old landmarks." there again. ing and hunting. Therefore, it "Getting sentimental, chief?" the Yet, nine years earlier, nobody Two Holdup not to a great deal of BY JULIAN EDWARDS.
    [Show full text]
  • Candida Auris
    microorganisms Review Candida auris: Epidemiology, Diagnosis, Pathogenesis, Antifungal Susceptibility, and Infection Control Measures to Combat the Spread of Infections in Healthcare Facilities Suhail Ahmad * and Wadha Alfouzan Department of Microbiology, Faculty of Medicine, Kuwait University, P.O. Box 24923, Safat 13110, Kuwait; [email protected] * Correspondence: [email protected]; Tel.: +965-2463-6503 Abstract: Candida auris, a recently recognized, often multidrug-resistant yeast, has become a sig- nificant fungal pathogen due to its ability to cause invasive infections and outbreaks in healthcare facilities which have been difficult to control and treat. The extraordinary abilities of C. auris to easily contaminate the environment around colonized patients and persist for long periods have recently re- sulted in major outbreaks in many countries. C. auris resists elimination by robust cleaning and other decontamination procedures, likely due to the formation of ‘dry’ biofilms. Susceptible hospitalized patients, particularly those with multiple comorbidities in intensive care settings, acquire C. auris rather easily from close contact with C. auris-infected patients, their environment, or the equipment used on colonized patients, often with fatal consequences. This review highlights the lessons learned from recent studies on the epidemiology, diagnosis, pathogenesis, susceptibility, and molecular basis of resistance to antifungal drugs and infection control measures to combat the spread of C. auris Citation: Ahmad, S.; Alfouzan, W. Candida auris: Epidemiology, infections in healthcare facilities. Particular emphasis is given to interventions aiming to prevent new Diagnosis, Pathogenesis, Antifungal infections in healthcare facilities, including the screening of susceptible patients for colonization; the Susceptibility, and Infection Control cleaning and decontamination of the environment, equipment, and colonized patients; and successful Measures to Combat the Spread of approaches to identify and treat infected patients, particularly during outbreaks.
    [Show full text]
  • Candida Species Identification by NAA
    Candida Species Identification by NAA Background Vulvovaginal candidiasis (VVC) occurs as a result of displacement of the normal vaginal flora by species of the fungal genus Candida, predominantly Candida albicans. The usual presentation is irritation, itching, burning with urination, and thick, whitish discharge.1 VVC accounts for about 17% to 39% of vaginitis1, and most women will be diagnosed with VVC at least once during their childbearing years.2 In simplistic terms, VVC can be classified into uncomplicated or complicated presentations. Uncomplicated VVC is characterized by infrequent symptomatic episodes, mild to moderate symptoms, or C albicans infection occurring in nonpregnant and immunocompetent women.1 Complicated VVC, in contrast, is typified by severe symptoms, frequent recurrence, infection with Candida species other than C albicans, and/or occurrence during pregnancy or in women with immunosuppression or other medical conditions.1 Diagnosis and Treatment of VVC Traditional diagnosis of VVC is accomplished by either: (i) direct microscopic visualization of yeast-like cells with or without pseudohyphae; or (ii) isolation of Candida species by culture from a vaginal sample.1 Direct microscopy sensitivity is about 50%1 and does not provide a species identification, while cultures can have long turnaround times. Today, nucleic acid amplification-based (NAA) tests (eg, PCR) for Candida species can provide high-quality diagnostic information with quicker turnaround times and can also enable investigation of common potential etiologies
    [Show full text]
  • Candida & Nutrition
    Candida & Nutrition Presented by: Pennina Yasharpour, RDN, LDN Registered Dietitian Dickinson College Kline Annex Email: [email protected] What is Candida? • Candida is a type of yeast • Most common cause of fungal infections worldwide Candida albicans • Most common species of candida • C. albicans is part of the normal flora of the mucous membranes of the respiratory, gastrointestinal and female genital tracts. • Causes infections Candidiasis • Overgrowth of candida can cause superficial infections • Commonly known as a “yeast infection” • Mouth, skin, stomach, urinary tract, and vagina • Oropharyngeal candidiasis (thrush) • Oral infections, called oral thrush, are more common in infants, older adults, and people with weakened immune systems • Vulvovaginal candidiasis (vaginal yeast infection) • About 75% of women will get a vaginal yeast infection during their lifetime Causes of Candidiasis • Humans naturally have small amounts of Candida that live in the mouth, stomach, and vagina and don't cause any infections. • Candidiasis occurs when there's an overgrowth of the fungus RISK FACTORS WEAKENED ASSOCIATED IMUMUNE SYSTEM FACTORS • HIV/AIDS (Immunosuppression) • Infants • Diabetes • Elderly • Corticosteroid use • Antibiotic use • Contraceptives • Increased estrogen levels Type 2 Diabetes – Glucose in vaginal secretions promote Yeast growth. (overgrowth) Treatment • Antifungal medications • Oral rinses and tablets, vaginal tablets and suppositories, and creams. • For vaginal yeast infections, medications that are available over the counter include creams and suppositories, such as miconazole (Monistat), ticonazole (Vagistat), and clotrimazole (Gyne-Lotrimin). • Your doctor may prescribe a pill, fluconazole (Diflucan). The Candida Diet • Avoid carbohydrates: Supporters believe that Candida thrives on simple sugars and recommend removing them, along with low-fiber carbohydrates (eg, white bread).
    [Show full text]
  • Vaginitis and Abnormal Vaginal Bleeding
    UCSF Family Medicine Board Review 2013 Vaginitis and Abnormal • There are no relevant financial relationships with any commercial Vaginal Bleeding interests to disclose Michael Policar, MD, MPH Professor of Ob, Gyn, and Repro Sciences UCSF School of Medicine [email protected] Vulvovaginal Symptoms: CDC 2010: Trichomoniasis Differential Diagnosis Screening and Testing Category Condition • Screening indications – Infections Vaginal trichomoniasis (VT) HIV positive women: annually – Bacterial vaginosis (BV) Consider if “at risk”: new/multiple sex partners, history of STI, inconsistent condom use, sex work, IDU Vulvovaginal candidiasis (VVC) • Newer assays Skin Conditions Fungal vulvitis (candida, tinea) – Rapid antigen test: sensitivity, specificity vs. wet mount Contact dermatitis (irritant, allergic) – Aptima TMA T. vaginalis Analyte Specific Reagent (ASR) Vulvar dermatoses (LS, LP, LSC) • Other testing situations – Vulvar intraepithelial neoplasia (VIN) Suspect trich but NaCl slide neg culture or newer assays – Psychogenic Physiologic, psychogenic Pap with trich confirm if low risk • Consider retesting 3 months after treatment Trichomoniasis: Laboratory Tests CDC 2010: Vaginal Trichomoniasis Treatment Test Sensitivity Specificity Cost Comment Aptima TMA +4 (98%) +3 (98%) $$$ NAAT (like GC/Ct) • Recommended regimen Culture +3 (83%) +4 (100%) $$$ Not in most labs – Metronidazole 2 grams PO single dose Point of care – Tinidazole 2 grams PO single dose •Affirm VP III +3 +4 $$$ DNA probe • Alternative regimen (preferred for HIV infected
    [Show full text]
  • AP-42, CH 9.13.4: Yeast Production
    9.13.4 Yeast Production 9.13.4.1 General1 Baker’s yeast is currently manufactured in the United States at 13 plants owned by 6 major companies. Two main types of baker’s yeast are produced, compressed (cream) yeast and dry yeast. The total U. S. production of baker’s yeast in 1989 was 223,500 megagrams (Mg) (245,000 tons). Of the total production, approximately 85 percent of the yeast is compressed (cream) yeast, and the remaining 15 percent is dry yeast. Compressed yeast is sold mainly to wholesale bakeries, and dry yeast is sold mainly to consumers for home baking needs. Compressed and dry yeasts are produced in a similar manner, but dry yeasts are developed from a different yeast strain and are dried after processing. Two types of dry yeast are produced, active dry yeast (ADY) and instant dry yeast (IDY). Instant dry yeast is produced from a faster-reacting yeast strain than that used for ADY. The main difference between ADY and IDY is that ADY has to be dissolved in warm water before usage, but IDY does not. 9.13.4.2 Process Description1 Figure 9.13.4-1 is a process flow diagram for the production of baker’s yeast. The first stage of yeast production consists of growing the yeast from the pure yeast culture in a series of fermentation vessels. The yeast is recovered from the final fermentor by using centrifugal action to concentrate the yeast solids. The yeast solids are subsequently filtered by a filter press or a rotary vacuum filter to concentrate the yeast further.
    [Show full text]
  • Bread Baking and Yeast
    Bread Baking and Yeast Electronic mail from Dr. Shirley Fischer Arends, Washington, D.C., native of Ashley, North Dakota. Dr. Arends is author of the book, The Central Dakota Germans: Their History, Language and Culture. Everlasting Yeast. The Dakota pioneers made this with dry cubes of yeast. In the evening they cooked 2 medium size potatoes (diced) in 1 quart of water for half an hour or until very soft. The potatoes were mashed in the same cooking liquid. To this liquid in which the potatoes were mashed were added 2 tablespoons of sugar and 1 tablespoon of salt. This mixture was left in the kettle in which the potatoes had been cooked, was covered and put in a warm place. Before going to bed, the 2 dry yeast cubes were added, after which another quart of warm water could be added. The kettle was wrapped in a warm blanket and set next to the cook stove. It had to be kept warm. In the morning, 1 pint was taken out, put in a sealed jar and placed in the cellar. Dough was made with the rest of the yeast. The reserved pint of yeast was then used the next time, along with the potatoes mixture replacing the yeast cubes. Thus the step of adding yeast cubes and water were eliminated. From the new mixture another pint was saved for the next time. The pint had to be used within a week or it would get too old and would not rise. One pint plus the potato mixture was enough to make 4 loaves of bread.
    [Show full text]
  • Fungi in Bronchiectasis: a Concise Review
    International Journal of Molecular Sciences Review Fungi in Bronchiectasis: A Concise Review Luis Máiz 1, Rosa Nieto 1 ID , Rafael Cantón 2 ID , Elia Gómez G. de la Pedrosa 2 and Miguel Ángel Martinez-García 3,* ID 1 Servicio de Neumología, Unidad de Bronquiectasias y Fibrosis Quística, Hospital Universitario Ramón y Cajal, 28034 Madrid, Spain; [email protected] (L.M.); [email protected] (R.N.) 2 Servicio de Microbiología, Hospital Universitario Ramón y Cajal and Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), 28034 Madrid, Spain; [email protected] (R.C.); [email protected] (E.G.G.d.l.P.) 3 Servicio de Neumología, Hospital Universitario y Politécnico la Fe, 46016 Valencia, Spain * Correspondence: [email protected]; Tel.: +34-60-986-5934 Received: 3 December 2017; Accepted: 31 December 2017; Published: 4 January 2018 Abstract: Although the spectrum of fungal pathology has been studied extensively in immunosuppressed patients, little is known about the epidemiology, risk factors, and management of fungal infections in chronic pulmonary diseases like bronchiectasis. In bronchiectasis patients, deteriorated mucociliary clearance—generally due to prior colonization by bacterial pathogens—and thick mucosity propitiate, the persistence of fungal spores in the respiratory tract. The most prevalent fungi in these patients are Candida albicans and Aspergillus fumigatus; these are almost always isolated with bacterial pathogens like Haemophillus influenzae and Pseudomonas aeruginosa, making very difficult to define their clinical significance. Analysis of the mycobiome enables us to detect a greater diversity of microorganisms than with conventional cultures. The results have shown a reduced fungal diversity in most chronic respiratory diseases, and that this finding correlates with poorer lung function.
    [Show full text]
  • Brewing Beer with Sourdough
    GigaYeast, Inc. Professional Grade Liquid Yeast For Brewers Brewing Beer with Sourdough October 2014 Jim Withee GigaYeast Inc. Brewing Beer with Sourdough The history of sourdough The microbiology of sourdough Brewing with sourdough Sour myth #1 “The lower the pH, the more sour it tastes” and Protonated Acid De-Protonated Acid Proton “…hydrogen ions and protonated organic acids are approximately equal in sour taste on a molar basis. “ Da Conceicao Neta ER et al. 2007 + = SOURNESS! Sour Myth #2 Sour taste is located in discreet locations of the tongue Bitter Sour Sour Salty Salty Sweet Receptors for various tastes, including sour, are distributed throughout the tongue! What is sourdough? A delicious tangy bread with a hard crust and soft chewy middle! Brewing Beer with Sourdough The history of sourdough The microbiology of sourdough Brewing with sourdough Sourdough is the first bread The first leavened breads ever made were likely sourdough Yum! Brewing Beer with Sourdough The history of sourdough The microbiology of sourdough Brewing with sourdough Sourdough is a microbial ecosystem of wild yeast and bacteria called a starter A sourdough starter is formed when yeast and bacteria from the flour, water, air and the baker inoculate a mixture of flour and water Sourdough starters can become stable over time Repeated re-use of the starter creates a stable ecosystem dominated by a small number of different species of yeast and bacteria that grow well together but keep intruding microbes at bay The sourdough microbiome The lactic acid bacteria create acetic and lactic acids to sour the bread and the yeast create CO2 and esters to leaven the bread and add character Yeast– one or more species including.
    [Show full text]
  • Oral Thrush A
    Oral thrush A. Introduction Oral thrush occurs when a yeast infection develops on the inside of your mouth and on your tongue. This condition is also known as oral candidiasis, oropharyngeal candidiasis, or, simply, thrush. The Candida albicans (C. albicans) fungus causes oral thrush. Candida is a normal organism in your mouth, but sometimes it can overgrow and cause symptoms. Oral thrush most often occurs in infants and toddlers. Oral thrush is typically mild and rarely causes complications. However, the condition can be problematic for those with weakened immune systems. B. Signs and Symtoms Oral thrush is usually harmless. It's common in babies and older people with dentures. It can be easily treated with medicines bought from a pharmacy. Adults Your mouth is red inside and you have white patches When you wipe off the white patches, they leave red spots that can bleed Other symptoms in adults are: 1.cracks at the corners of the mouth 2.not tasting things properly 3.an unpleasant taste in the mouth 4.pain inside the mouth (for example, a sore tongue or sore gums) 5.difficulty eating and drinking Oral thrush in adults isn't contagious. Babies A white coating on the tongue like cottage cheese – this can't be rubbed off easily Sometimes there are white spots in their mout Other symptoms in babies are: 1.they don't want to feed 2.nappy rash Babies can pass oral thrush on through breastfeeding. This can cause nipple thrush in mothers. C. Treatment Treatment for oral thrush varies depending on your age and overall health.
    [Show full text]
  • Vaginitis No Disclosures Related to This Topic
    Vaginitis No disclosures related to this topic Is the wet prep out of the building? Images are cited with permissions Barbara S. Apgar, MD, MS Professor of Family Medicine University of Michigan Health Center Michigan Medicine Ann Arbor, Michigan Women with vaginal discharge Is vaginal discharge ever “normal ”? Normal 30% Bacterial vaginosis 23-50% Few primary studies and most of low quality. Candida vaginitis 20-25% Quantity and quality of vaginal discharge varies considerably across women and during the Mixed 20% menstrual cycle. Desquamative inflammatory 8% Symptom of vaginal discharge is non-specific. Vaginitis Vaginal discharge is often thought to be vaginitis. Trichomoniasis 5-15% Vaginal symptoms are very common Patient with chronic vaginal discharge Presence or absence of a microbe corresponds poorly with the presence or absence of 17 year old GO complains of lots of heavy white symptoms. vaginal discharge which is bothersome. No agreement about timing, color or Regular periods, denies any sexual activity. characteristics of discharge among women with Numerous evaluations for STI’s, all negative. vaginal discharge Treated for vaginal candida, BV and trich Most women think vagina should be “dry ”. although there was no evidence for any Vaginal wetness may be normal . infection and did not resolve discharge. Schaaf et al. Arch Intern Med 1999;150. Physiologic vaginal discharge 17 year old Chronic vaginal Patients and providers may consider that a thick discharge white discharge is most frequently caused by candidiasis. Always wears a pad May lead to repeated use of unnecessary antifungal therapy and prompt concerns of Diagnosis? recurrent infection if not resolved.
    [Show full text]