Covid-19 and Gender: Lower Rate but Same Mortality of Severe Disease In
Raimondi et al. BMC Pulm Med (2021) 21:96 https://doi.org/10.1186/s12890-021-01455-0 RESEARCH ARTICLE Open Access Covid-19 and gender: lower rate but same mortality of severe disease in women—an observational study Federico Raimondi1,2 , Luca Novelli1, Arianna Ghirardi3, Filippo Maria Russo2,4, Dario Pellegrini5, Roberta Biza1,2, Roberta Trapasso1,2, Lisa Giuliani1,2, Marisa Anelli1,2, Mariangela Amoroso1,2, Chiara Allegri1,2, Gianluca Imeri1, Claudia Sanflippo1, Sofa Comandini1, England Hila2,4, Leonardo Manesso2,4, Lucia Gandini2,4, Pietro Mandelli2,4, Martina Monti2,4, Mauro Gori5, Michele Senni5, Ferdinando Luca Lorini4, Marco Rizzi6, Tiziano Barbui3, Laura Paris7, Alessandro Rambaldi2,7, Roberto Cosentini8, Giulio Guagliumi5, Simonetta Cesa9, Michele Colledan10, Maria Sessa11, Arianna Masciulli3, Antonello Gavazzi3, Sabrina Buoro12, Giuseppe Remuzzi13, Piero Ruggenenti14, Annapaola Callegaro15, Andrea Gianatti16, Claudio Farina15, Antonio Bellasi17, Sandro Sironi18,19, Stefano Fagiuoli20 and Fabiano Di Marco1,2*HPG23 Covid-19 Study Group Abstract Background: Gender-related factors might afect vulnerability to Covid-19. The aim of this study was to describe the role of gender on clinical features and 28-day mortality in Covid-19 patients. Methods: Observational study of Covid-19 patients hospitalized in Bergamo, Italy, during the frst three weeks of the outbreak. Medical records, clinical, radiological and laboratory fndings upon admission and treatment have been col- lected. Primary outcome was 28-day mortality since hospitalization. Results: 431 consecutive adult patients were admitted. Female patients were 119 (27.6%) with a mean age of 67.0 14.5 years (vs 67.8 12.5 for males, p 0.54). Previous history of myocardial infarction, vasculopathy and former ± ± = smoking habits were more common for males.
[Show full text]