Brain & Behavior Research Foundation INTERNATIONAL30th Anniversary Celebration AWARDS DINNER

FRIDAY, OCTOBER 27th The Pierre 2017 Celebrating our Pardes Humanitarian Prizewinners and Outstanding Achievement Prizewinners WELCOME

Welcome to our 2017 International Awards Dinner and our celebration of the 30th anniversary of the Brain & Behavior Research Foundation. This year’s program honors our 2017 Outstanding Achieve- ment Prizewinners, the recipient of the Pardes Humanitarian Prize in Mental Health, and, includes a special Pardes Humanitarian Prize Honorary Tribute to the late Constance E. Lieber, whose leadership as President and President Emeritus of our Foundation, touched so many lives. Connie was one of the world’s greatest public advocates for mental health and psychiatric research and care and she continues to be our guiding light.

This year’s Pardes Humanitarian Prize honors Doctors Without Borders/Médecins San Frontières (MSF) for their transformative work in providing mental health care as an integrated component of medical aid during natural and man-made emergencies and chronic crises. Founded in 1971, MSF provides aid in nearly 60 countries and received the 1999 Nobel Peace Prize for its independent, rapid, and fearless work during humanitarian catastrophes.

Bestowed annually since 2014, the Pardes Prize recognizes a person(s) or organization whose human- itarian work is transformative and of great magnitude, changing the lives and bringing the joy of living to those facing challenges to mental health. The Prize focuses public attention on the burden of mental illness on individuals and on society, and the urgent need to expand and enhance mental health services both in the developed world and in developing countries. The Prize was named in honor of Dr. Herbert Pardes, the first recipient of the award. One of Dr. Pardes’ many contributions to our field has been his founding and continued leadership of the Brain & Behavior Research Foundation’s Scientific Council, a volunteer group of 177 pre-eminent mental health professionals across disciplines in brain and behavior research, who select Foundation Grantees from more than 1,200 grant applications each year.

Nine innovative and exceptional scientists—many of them Foundation Grantees—will also be honored this evening for their contributions to the advancement of our understanding and treatment of schizophrenia, bipolar disorder, anxiety, trauma, and child and adolescent psychiatry. Their work is distinguished by their use of cutting-edge technology and a devotion to finding personalized therapies that will improve our care for those living with mental illness, as well as seeking preventive and diagnostic tools for the future.

We are delighted to have you here to celebrate the impactful progress being made in brain and behav- ior research. Our shared commitment to scientific advancement will change what it means to live with a mental illness and pave the way for more people to live full, happy and productive lives.

Thank you for your ongoing support. Enjoy the evening!

Sincerely,

Jeffrey Borenstein, M.D. President & CEO Brain & Behavior Research Foundation 4 Board of Directors and Dinner Committee Sponsors and Contributors

8 Pardes Humanitarian Prize in Mental Health Honoree : Doctors Without Borders/Médecins Sans Frontières (MSF) Honorary Tribute : Constance E. Lieber

11 OUTSTANDING ACHIEVEMENT PRIZES

Lieber Prize for Schizophrenia Research John M. Davis, M.D. University of Illinois at Chicago

12 Maltz Prize for Innovative & Promising Schizophrenia Research Deanna L. Kelly, Pharm.D., BCPP University of Maryland School of Medicine

13 Colvin Prize for Mood Disorders Research Hilary P. Blumberg, M.D. Yale School of Medicine

Tadafumi Kato, M.D., Ph.D. RIKEN Brain Science Institute, Japan

Mary L. Phillips, M.D., M.D. (Cantab) University of Pittsburgh, Western Psychiatric Institute and Clinic

16 Ruane Prize for Child & Adolescent Psychiatric Research Nathan A. Fox, Ph.D. The University of Maryland, College Park

Charles A. Nelson III, Ph.D. Harvard Medical School & Boston Children’s Hospital

Charles H. Zeanah, Jr., M.D. Tulane University School of Medicine

19 Goldman-Rakic Prize for Cognitive Neuroscience Trevor W. Robbins, Ph.D. University of Cambridge, UK

20 Previous Outstanding Achievement Prizewinners

24 Scientific Council board of directors dinner committee

President & CEO Anne and Ronald Abramson Jeffrey Borenstein, M.D. Carol Atkinson Patricia and Eric Bam President, Janet and Donald Boardman Scientific Council Raymonde and J. Anthony Boeckh Herbert Pardes, M.D. Jeffrey Borenstein, M.D. Susan Lasker Brody, MPH Suzanne and John Golden OFFICERS Bonnie and Alan Hammerschlag Marla Press and Ken Harrison Chairman Kathy and John Hollister Stephen A. Lieber Stephen A. Lieber Carole and Harvey Mallement Vice President Tamar and Milton Maltz Anne E. Abramson Miriam Katowitz and Arthur Radin, CPA Léa Dartevelle and Marc R. Rappaport Secretary Virginia and Mark Silver, M.D. John B. Hollister Kenneth Sonnenfeld, Ph.D, J.D. Barbara and John Streicker Treasurer Barbara Toll Arthur Radin, CPA Frances and Robert Weisman, Esq.

DIRECTORS Carol A. Atkinson Eric Bam Donald M. Boardman J. Anthony Boeckh Susan Lasker Brody, MPH Suzanne Golden Bonnie D. Hammerschlag John Kennedy Harrison II Carole H. Mallement Milton Maltz Marc R. Rappaport Virginia M. Silver Kenneth H. Sonnenfeld, Ph.D., J.D. Barbara K. Streicker Barbara Toll Robert Weisman, Esq.

4 Supporters

GALAXY INDIVIDUAL Alpine Woods Capital Investors, LLC Linda Bauer Borrego Foundation, Inc. Louisa Benton Lieber Family Susan Lasker Brody, MPH Joanne and George Bundschuh COSMIC Lillian Clagett Tamar and Milton Maltz Daniels Family Foundation Inc. Rose DiMartino CELESTIAL Annikki Elkind NewYork-Presbyterian Gloria & Hilliard Farber Foundation Benjamin Haskin STAR Bonnie Becker Krystal, M.D. and John Krystal, M.D. Anne and Ronald Abramson Family Foundation JSquared Press, Inc. Graham Boeckh Foundation Jill and Sanford Sirulnick Bonnie and Alan Hammerschlag University of Pittsburgh Columbia University The John L. & Sue Ann Weinberg Foundation King & Spalding LLP Ann Weiner Joan M. Leiman, M.D. Marni Zabel and Gerry Modell

BENEFACTOR HONOR ROLL Janina and Andrew Boral, M.D. Wallace Currey Ellyn Roth and Harold Pincus, M.D. AMBASSADOR Carol Trager and Matthew Carrano GNYHA Ventures, Inc. Virginia and Mark Silver, M.D.

VIP Jayamin and Dhruvika Patel Amin Marina Benaur, M.D. and Marc Dubin Janet and Donald Boardman Collins Building Services, Inc. Léa Dartevelle and Marc Rappaport Maria and Dan Doyle Beth Elliott Rita and Robert Gadsden Suzanne and John Golden Horizon Group Properties, Inc. Lou Innamorato Miriam Katowitz and Arthur Radin Ann and Rob Laitman Joan and Gregg Popkin Lilian Sicular Elizabeth Stumbo and Stephen Taylor Janet Susin Barbara Toll Weill Cornell Medicine

5 Pardes Humanitarian PRIZE in mental health

dr. herbert pardes

This international Prize recognizes a physician, sci- No one has better described the goals of this interna- entist, organization, or public citizen whose extraor- tional Prize than Dr. Pardes himself: “Mental illness is dinary contribution has made a profound and lasting the largest single health challenge in the world. For impact by improving the lives of people suffering from many decades society has recognized major contri- mental illness and by advancing the understanding butions in basic science, clinical research and clinical of mental health. Established in 2014, the Pardes care in the non-psychiatric health fields. The Pardes Humanitarian Prize in Mental Health was named in Humanitarian Prize has been established to honor honor of Dr. Herbert Pardes, the first recipient of individuals who comprehensively care, teach, inves- the award. tigate, work and passionately advocate for improv- ing the mental health of society, and who have had Bestowed annually, the Prize recognizes a person(s) a powerful impact on reducing the pain inflicted by or organization whose humanitarian work is trans- psychiatric illness.” formative and of great magnitude, changing lives and bringing the joy of living to those facing challenges to mental health. Nominations are solicited worldwide; Rendering of The Pardes Humanitarian Prize medal the recipient of the Prize is chosen by a distinguished featuring Hygeia, Goddess of Health. Committee of eleven members and receives an hon- orarium. The Pardes Humanitarian Prize in Mental Health focuses public attention on the burden of mental illness on individuals and society. It also recog- nizes the urgent need to expand and enhance mental health services in both the developed world and devel- oping countries.

6 Pardes Humanitarian PRIZE selection committee

Herbert Pardes, M.D. Helen S. Mayberg, M.D. Executive Vice Chairman of the Board of Trustees Professor of Psychiatry, Neurology, and Radiology NewYork-Presbyterian Hospital Dorothy C. Fuqua Chair in Psychiatric Celso Arango, M.D., Ph.D. Neuroimaging and Therapeutics Head of Child and Adolescent Psychiatry Service Emory University School of Medicine Hospital General Universitario Gregoria Maranon, Madrid Vikram Patel, Ph.D., F.Med.Sci. Jack D. Barchas, M.D. Pershing Square Professor of Global Health Chair, Department of Psychiatry and Wellcome Trust Principal Research Fellow Weill Cornell Medical College Department of Global Health and Social Medicine Psychiatrist-in-Chief Harvard Medical School. NewYork-Presbyterian Hospital Judith L. Rapoport, M.D. William T. Carpenter, Jr., M.D. Chief, Child Psychiatry Branch Professor of Psychiatry and Pharmacology National Institute of Mental Health (NIMH/NIH) Director, Maryland Psychiatric Research Center University of Maryland School of Medicine Norman Sartorius, M.D., Ph.D., F.R.C.Psych. President,Association for the Improvement Robert R. Freedman, M.D. of Mental Health Professor and Chairman, Department of Psychiatry Programmes Geneva, Switzerland University of Colorado School of Medicine Myrna M. Weissman, Ph.D. Dilip V. Jeste, M.D. Diane Goldman Kemper Professor of Epidemiology Associate Dean for Healthy Aging and Senior Care and Psychiatry Estelle and Edgar Levi Chair in Aging Chief, Division of Epidemiology Distinguished Professor of Psychiatry Columbia University College of Physicians and Surgeons and Neurosciences New York State Psychiatric Institute

Director, Sam and Rose Stein Institute for Research on Aging University of California, San Diego

7 Pardes Humanitarian PRIZE in mental health

awarded to: doctors without borders /Medecins Sans Frontieres

Photo credit : Ton Koene

Doctors Without Borders/Médecins Sans Frontières Since then, the scope of interventions originally tailored (MSF) provides emergency medical aid in response to towards survivors of disasters has been broadened to armed conflicts, natural disasters, famines, and epidem- include more and more integrated activities within medical ics. MSF doctors and nurses are often seen treating programs. Today, MSF considers providing mental health physical ailments: bandaging the war-wounded, rehy- care a primary objective in a variety of contexts. Mental drating a cholera patient, or performing an emergency Health and Psychosocial Support (MHPSS) is necessary cesarean section. But for more than 20 years, MSF has and relevant during natural and man-made emergencies, also been providing vital psychiatric and psychological during chronic crises, and as an integrated component of care to people ravaged by man-made or natural disas- medical care. Mental health care increases the efficacy ter. The organization currently has mental health related of medical treatments, and is an important component programs in 41 countries across five continents treating of programs focused on treating HIV/AIDS, tuberculosis, adults and children. malnutrition, and non-communicable diseases.

Violence, armed conflict, disease outbreaks, natural MSF mental health programs now reach tens of thousands disasters, sexual violence, and neglect can be profoundly worldwide. Among them are Syrian children at a hospital traumatic for individuals who live through them and can in northern Jordan, typhoon survivors in the Philippines, lead to severe mental health issues both in the moment survivors of sexual violence in Haiti, cholera victims in and beyond. Depression and anxiety can immobilize Yemen, and displaced people across the globe, includ- people at just the time when they need to take action ing Iraq, Lebanon, Italy, Mexico, Tanzania, and Sudan. for themselves and their families. MSF intervenes where Recognizing that the long-term psychological impact of there is a lack of mental health services in areas afflicted humanitarian crises are frequently underestimated or by natural and man-made disasters, and as a support to undertreated, MSF plans to expand its mental health pro- other medical activities. grams around the globe.

The first MSF mental health interventions were in Through their tremendous work at the frontlines, in often Armenia in 1990 after the earthquake. In the 1990s, MSF dangerous and volatile areas of the world, the physicians, initiated mental health programs in Gaza, the Balkans and nurses and staff of MSF provide an unwavering example in Eastern Europe, and in 1998, MSF formally recognized of what it truly means to be a humanitarian. the need to implement mental health and psychosocial interventions as part of their emergency work.

8 Honorary Pardes Humanitarian PRIZE in mental health

Constance E. Lieber transformed her family’s expe- rience with mental illness into a lifetime of extraordi- nary advocacy and support for psychiatric research of awarded to: schizophrenia, depression, and other mental illnesses. constance E. lieber She was unwavering in her dedication to alleviating the suffering caused by mental illness and banishing the stigma that for too long has been associated with Connie Lieber was a global champion for mental health psychiatric disorders. and an extraordinary humanitarian. Not only did she work tirelessly to support scientists in the field, but It was over 30 years ago at a symposium at Columbia guided by her own personal experience and compas- University when Dr. Herbert Pardes first met Connie sion, she informally advised thousands of parents who Lieber and her husband Stephen Lieber. They spoke were desperately seeking help for their children. with him about supporting mental health programs and research on mental illness. That conversation has Married for over 66 years, Connie and Steve Lieber led to $380 million in grants from the Brain & Behavior were dedicated partners, leading the way in public Research Foundation to more than 4,500 of the most advocacy and philanthropic support of psychiatric innovative scientists around the world. research. At Columbia University, they founded two centers of excellence–the Lieber Recovery and Reha- Connie Lieber served as President of the Brain & bilitation Clinic and the Lieber Center for Schizophre- Behavior Research Foundation, formerly known as the nia Research and Treatment. At Williams College, National Alliance for Research on Schizophrenia and they were the founders of the undergraduate neu- Depression (NARSAD) from 1989 to 2007. She then roscience program. In 2011, they created the Lieber continued to provide leadership as President-Emer- Institute for Brain Development, affiliated with Johns ita until 2016. Under her leadership, the Foundation Hopkins University. became a major global institution in mental health and psychiatric research. She and Steve through their lead- For her extraordinary and enduring legacy of generos- ership and generosity transformed the private sector ity, brilliance and compassion, which has inspired others with their support for psychiatric research. to improve the lives of people suffering from mental illness, we honor Constance E. Lieber.

9 Outstanding Achievement Prizes for 2017

Tonight we celebrate the transformative power of neuroscience and psychiatric research to improve the lives of those with mental illness. Nine exceptional scientists, selected by the Brain & Behavior Research Foundation’s Scientific Council, will be honored for their outstanding lifetime achievements in brain and behavior science. The Outstanding Achievement Prizes are awarded annually and include the:

Lieber Prize for Schizophrenia Research Colvin Prize for Mood Disorders Research Established in 1987 by Constance and Stephen Lieber to bring Established in 1993, this prize was formerly known under the public recognition to the outstanding discoveries being made in successive titles of the Selo Prize, Falcone Prize, and Bipolar schizophrenia research. This prize carries an award of $50,000. Mood Disorders Prize. The prize was renamed in 2012 in honor of the late Oliver D. Colvin, Jr., a great benefactor of the Foun- Maltz Prize for Innovative dation who left the largest single contribution in the Founda- & Promising Schizophrenia Research tion’s history. This prize carries an award of $50,000. Established in 2004, the prize was formerly known as the Baer Prize and was renamed in 2016 in honor of Board Members Ruane Prize for Childhood Milton and Tamar Maltz. The Maltz Prize provides $40,000 to & Adolescent Psychiatric Research an investigator who has undertaken innovative and promising This prize was initiated in 2000 by philanthropists Joy and research in schizophrenia. Winners of this prize are selected William Ruane to recognize important advances in understand- by the Lieber Prize recipient(s) of the same year. ing and treatment of early-onset brain and behavior disorders. This prize carries an award of $50,000. The Outstanding Achievement Prizewinners are dedicated teachers and scientists who represent models of accomplish- Goldman-Rakic Prize for Cognitive Neuroscience ment for younger scientists in brain and behavior research. This prize was created by Constance and Stephen Lieber in memory of Patricia Goldman-Rakic, Ph.D., a distinguished neu- roscientist renowned for discoveries about the brain’s frontal lobe, after her tragic death in an automobile accident in 2003. The prize carries an award of $40,000.

Scientific Council Prize Committees

Lieber Prize Ruane Prize William E. Bunney, Jr., M.D. (Chair) Judith L. Rapoport, M.D. (Chair) Arvid E. Carlsson, M.D. Joseph T. Coyle, M.D. Kenneth S. Kendler, M.D. Rachel G. Klein, Ph.D. Philip Seeman, M.D., Ph.D. James E. Leckman, M.D. Carol Tamminga, M.D. Daniel Pine, M.D. Daniel R. Weinberger, M.D. Goldman-Rakic Prize Colvin Prize Jack D. Barchas, M.D. (Chair) Robert M. Post, M.D. (Chair) Huda Akil, Ph.D. Wade Berrettini, M.D., Ph.D. Jonathan D. Cohen, M.D., Ph.D. William E. Bunney, Jr., M.D. Paul Greengard, Ph.D. Jan A. Fawcett, M.D. Bruce S. McEwen, Ph.D. Frederick K. Goodwin, M.D. Michael I. Posner, Ph.D. Robert M.A. Hirschfeld, M.D. Solomon H. Snyder, M.D., Ph.D., DSc Husseini K. Manji, M.D. Leslie G. Ungerleider, Ph.D. 10 lieber PRIZE For Outstanding Achievement in Schizophrenia Research

john m. davis, M.D. Gilman Professor of Psychiatry “I am profoundly humbled to join the alumni of recipients of the and Research Lieber Prize for Schizophrenia Research. I particularly want to acknowledge and honor the generosity of Constance and Professor of Medicine University of Illinois at Chicago Stephen Lieber for whom the award is named. Advances in schizophrenia research in the 30 years since the award was established are exponential and linked definitively to their support and that of the Brain & Behavior Research Founda- tion. Clinical scientists form a bridge between basic research and the patient and can translate clinical findings or obser- vations back to the basic scientists. My hope for this award is to serve as a stimulus to encourage more clinicians towards clinical research.”

John M. Davis attended Princeton Univer- dopamine in schizophrenia, leading to the Dr. Davis has also studied nutrition and sity, received his medical degree from Yale development of partial dopamine blockers his work on the role of adequate dietary University School of Medicine, interned as antipsychotic drugs. intake of omega-3 fatty acids has resulted at Massachusetts General Hospital, and in changes to the FDA guidelines and the went back to Yale for his psychiatric res- Among his other accomplishments, Dr. 2015 Dietary Guidelines for Americans. idency. He received his research training Davis wrote the first science-based text- Dr. Davis currently studies gene expres- at the National Institute of Health. He is book on psychopharmacology as a guide sion abnormalities in schizophrenia and now in the department of psychiatry at for psychiatrists seeking to use medica- conducts clinical trials addressing the the University of Illinois at Chicago School tions more effectively. In 1975, he also disease. He has been a member of numer- of Medicine. performed the first meta-analysis study ous national scientific advisory com- in psychiatry (the second in medicine). mittees and editorial boards, and is the Dr. Davis did the first studies of how anti- Meta-analyses use mathematical tech- recipient of several awards including the psychotic drugs are metabolized in the niques to summarize data from multiple American College of Psychiatrists’ Stanley body and how this process may impact clinical trials. Dr. Davis’ first meta-anal- Dean Award for Research in Schizophre- their efficacy and side effects. His work ysis provided convincing evidence that nia for 2006. showed that the therapeutic doses were maintenance antipsychotic, mood stabi- much lower than previously thought. His lizers and antidepressant drugs could help early research also included work on the prevent future schizophrenic episodes. involvement of the neurotransmitter “ Lieber Prize Selection Committee Chairman Dr. William Bunney, said Davis “has a long, extremely distinguished career involving pioneering work relevant to the etiology and treatment of schizo- phrenia. He performed the first meta-analysis in psychiatry on the prevention of relapse in schizo- phrenia with maintenance anti-psychotics, the first determinations of anti-psychotic plasma levels and their drug interactions, and wrote the first science-based textbook in psychiatry.”

” 11 maltz PRIZE For Innovative & Promising Schizophrenia Research

Deanna L. Kelly, Pharm.D., BCPp Professor “The Brain & Behavior Research Foundation is the University of Maryland School premier organization worldwide truly committed to of Medicine funding innovative projects and science in the mental Affiliate Professor health arena. It has impacted and inspired countless University of Maryland School young scientists around the globe, undoubtedly shaping of Pharmacy the early years of many prominent thought leaders in Director, Treatment Research Program the field. To receive recognition for my work from this Maryland Psychiatric Research Center organization is humbling and I am truly honored and privileged to be a recipient of the Maltz Prize for Inno- vative & Promising Schizophrenia Research.”

Deanna L. Kelly is Professor of Psychia- completed one of the few large clinical Dr. Kelly has co-authored or authored 16 try at University of Maryland Baltimore trials in women with schizophrenia, and books and book chapters and has pub- School of Medicine and Affiliate Pro- she runs a unique large multinational trial lished more than 160 peer-reviewed fessor in the School of Pharmacy. She is to improve outcomes with clozapine treat- manuscripts. She serves as a founding currently Director and Chief of the Treat- ment in people of African descent. She has and current Associate Editor for Clinical ment Research Program at the Maryland completed a handful of unique studies in Schizophrenia and Related Psychoses, is a Psychiatric Research Center. Dr. Kelly specific schizophrenia subgroups and she member of the American College of Neu- received her bachelor’s and doctoral is running the only inpatient clinical trial ropsychopharmacology and currently is degrees in pharmacy, at Duquesne Uni- focusing on the removal of dietary gluten the President for the College of Psychi- versity. She completed residency training in people with schizophrenia who have atric and Neurologic Pharmacists. in psychiatric pharmacy practice at the antibodies to the gluten protein, gliadin. University of Maryland. The overarching goal of her research is to help develop personalized and beneficial Dr. Kelly’s research focuses on treatment treatments to enable people with schizo- research, mostly conducting clinical trials phrenia to have access to potentially life with innovative treatment targets and for altering treatments. understudied populations. Dr. Kelly has “ John M. Davis, M.D., the 2017 recipient of the Lieber Prize, said Dr. Kelly “is truly one of the few clinical scientists who investigate basic phenomena at the level of the person with schizophrenia. Academia-based clinical trial work, asking important questions and studying important outcomes by applying novel treatments and targets, is few and far between. She has completed many important clinical trials that have helped shape the way the field views personalized medicine in a translational clinical trial framework. Her most recent clinical trial work in women is commendable and her work studying people with gluten antibodies is remarkable and exciting, helping to shape new treatments and studying new mechanisms, for a subgroup with schizophrenia.” ” 12 COLVIN PRIZE For Outstanding Achievement In Mood Disorders Research

Hilary P. Blumberg, M.D.

John and Hope Furth Endowed Professor “Receiving the Colvin Award is a peak of my research of Psychiatric Neuroscience career – at each stage, BBRF has provided the Professor of Psychiatry, Radiology and support critical to propel me to the next through Biomedical Imaging the Young and Independent Investigator pro- Faculty Child Study Center grams, and deeply meaningful Klerman Award. I Director, Mood Disorders Research Program Yale University School of Medicine am humbled to receive the Colvin and will do my very best to honor it by accelerating on the research Scientific Council Member course to reduce suffering from mental illness and 2006 Klerman Prize for Exceptional training the next generation of young investigators.” Clinical Research 2006 Independent Investigator 2002 Young Investigator

Hilary P. Blumberg is the John and Hope one of the first demonstrations of brain ences in the trajectories of develop- Furth Professor of Psychiatric Neurosci- differences in individuals while experi- ment of the brain circuitry during ado- ence, Professor of Psychiatry, Radiology encing manic symptoms of BD. She and lescence that has shaped the view of and Biomedical Imaging and Faculty at her team subsequently showed brain BD as a disorder of neurodevelopment the Child Study Center at the Yale School differences in individuals experiencing and of adolescence as an important of Medicine. She is Director of the Yale depression, and differences present period. Her more recent areas of study Mood Disorders Research Program that during asymptomatic times that may place include some of the first multi-modality brings together scientists from multiple them at risk for episodes. She has used research on the brain circuitry of suicide disciplines across the campus to study innovative, integrative approaches with risk in adolescents and young adults, as mood and related disorders. She gradu- neuroimaging to show negative influences well as changes in the brain in BD with age ated summa cum laude in neuroscience of genetic variations and early life stress later in life, and with her Brain Emotion from Harvard University and completed (such as child abuse and neglect), and sal- Circuitry-Targeted Self-Monitoring and her medical degree, psychiatry training utary influences of pharmacological and Regulation Therapy (BE-SMART) psy- and specialty training in research in neu- non-pharmacological interventions, on chobehavioral treatment. Dr. Blumberg’s roimaging of neuropsychiatric disorders at the structure and function of the brain’s research brings great hope that on the Cornell University Medical College. circuitry related to emotional processing. horizon are new methods for early detec- tion, targeted treatments, improved prog- Dr. Blumberg is an international leader in Dr. Blumberg is perhaps best known nosis, and prevention of BD progression research in bipolar disorder (BD) in chil- for her pioneering work in these areas and suicide. dren, adolescents, and adults. Among her of research in youths with BD. This has important pioneering contributions was included research evidence of differ- “ Robert M. Post, M.D., Chair of the Colvin Prize Selection Committee, said Dr. Blumberg “was the first to research and identify structural and functional brain differences in adolescents with bipolar disorder, impli- cating both gray and white matter as targets for bipolar disorder preventive and treatment interventions. She is currently a leading member of a new international consortium that is forming to study suicide in affective disorders. With her expertise and enthusiasm, her mentorship has been transformative in the development of young researchers focused on study of affective disorders.” ” 13 COLVIN PRIZE For Outstanding Achievement In Mood Disorders Research

Tadafumi Kato, M.D., Ph.D. Senior Team Leader, “I have been dedicated to the study of bipolar disorder for Laboratory for Molecular Dynamics of Mental Disorders nearly three decades. I think that we have made substantial progress in these decades. In spite of the progress, I regret Deputy Director that our neurobiological findings of bipolar disorder have RIKEN Brain Science Institute not yet changed the clinical practice. When I mainly con- 2008, 2000 Independent Investigator centrated on clinical practice in the past, feedback from patients encouraged me every day. On the other hand, it takes many years for patients to benefit from the outcome of neurobiological research, and thus basic researchers rarely feel rewarded for their effort. Being awarded the Colvin Prize, a prestigious prize focusing on mood disorder research, has encouraged me to pursue this difficult but meaningful research for the rest of my life.”

Tadafumi Kato is a Senior Team Leader accumulated mitochondrial DNA dele- His research group has also been working and the Deputy Director of RIKEN Brain tions in the brain, Dr. Kato’s research on genomic analyses of bipolar disorder, Science Institute. He received an M.D. team has found that the mice show publishing one of the first comprehen- from the University of Tokyo, with resi- recurrent spontaneous depression-like sive analyses of transcribed genes in dency training at the University of Tokyo episodes which responded to lithium, the postmortem brains of patients with Hospital. He received his Ph.D. from Shiga and has identified a region of the brain bipolar disorder. Since then, he and his University of Medical Science, where he involved in these episodes. This would colleagues have applied similar technol- began his work on magnetic resonance be the first animal model of spontaneous ogies to clinical samples and also animal spectroscopy in bipolar disorder and recurrent depression-like episodes that models to find dysfunctional mechanisms identified impaired energy metabolism would be potentially useful for develop- within bipolar disorder and related dis- in the brain. ment of mood stabilizers. The local mito- orders. The studies have revealed the chondrial dysfunction was verified in the role of a type of cellular stress in mono- In studying the neurobiology of bipolar postmortem brains of patients with mito- zygotic twins discordant for bipolar dis- disorder, Dr. Kato found that mitochon- chondrial disease with mood symptoms. order, the role of a genetic element called drial DNA deletions were accumulated Dr. Kato’s series of work has established retrotransposon LINE-1 in schizophrenia, in the postmortem brains of bipolar the role of mitochondrial dysfunction in and de novo (newly generated) mutations patients. Using model mice that have bipolar disorder. related to bipolar disorder. “ Robert M. Post, M.D., Chair of the Colvin Prize Selection Committee, said Kato’s significant accom- plishments include the verification of mitochondrial dysfunction in postmortem brains of patients with mitochondrial disease with mood symptoms, and the creation of the first animal model of spontaneous recurrent depression-like episodes. “Dr. Kato has vastly improved our knowledge of the causes of the disorder, created hope for patients and families and inspired many scientists at all levels.”

” 14 COLVIN PRIZE For Outstanding Achievement In Mood Disorders Research

Mary L. Phillips M.D., M.D. (Cantab) Pittsburgh Foundation-Emmerling Endowed Chair in Psychotic Disorders “Winning this award is a huge honor, not just for me, but for all the hard working members of my research Professor in Psychiatry and Clinical Translational Science team, and my collaborators and mentors throughout University of Pittsburgh, Western Psychiatric the years. I am so grateful to the Brain & Behavior Institute and Clinic Research Foundation for recognizing our work, and Scientific Council Member the potential our research has to develop new and effective treatments for individuals with otherwise 2005 Independent Investigator devastating psychiatric illnesses.”

Mary L. Phillips is the Pittsburgh Foun- functional and structural abnormalities neural biomarkers of mood disorders, as dation-Emmerling Endowed Chair in in brain circuits for emotion processing a step toward developing new interven- Psychotic Disorders, and Professor in and regulation and reward processing tions for individuals with these disorders. Psychiatry and Clinical and Translational that are associated with specific psychi- Science in the University of Pittsburgh. atric disorders. Her research also focuses In 2017, Dr. Phillips became President She heads the Clinical and Translational on identifying the neurodevelopmental Elect of the Society of Biological Psy- Affective Neuroscience Program in the trajectories in these circuitries that are chiatry. She has served on the Member- Department of Psychiatry at the Univer- associated with the development of such ship Committee of the American College sity of Pittsburgh. Dr. Phillips trained in disorders in youth and infants, and the of Neuropsychopharmacology, and on Medicine at Cambridge University, UK, extent to which these neuroimaging tech- Program Committees of both the Society and in Psychiatry at the Maudsley Hospi- niques can identify biomarkers reflecting of Biological Psychiatry and the Ameri- tal and the Institute of Psychiatry, King’s underlying processes that may increase can College of Neuropsychopharmacol- College, University of London, UK. the future risk for these disorders in as ogy, the latter of which awarded her the yet unaffected youth. Her more recent Joel Elkes Research Prize in 2014. She has Dr. Phillips’ research focuses on using work examines how neuromodulation mentored over 60 junior investigators, neuroimaging techniques to discover techniques can be targeted on identified and has authored or co-authored more than 300 publications. “ Robert M. Post, M.D., Chair of the Colvin Prize Selection Committee, said: “Dr. Phillips has led the field in employing state-of-art neuroimaging techniques to identify markers of reward and emotional regulation neural circuitry function and structure that characterize youth with and youth at risk of future bipolar disorder and other mood disorders, including neurobiological measures that identify at-risk youth who are most likely to develop worsening psychopathology and mood disorders in the future. She has had a substantial impact on the field of psychiatry through her research activities, her teaching and mentorship of the next generation of academic and physician scientists both nationally and internationally.”

” 15 ruane PRIZE for Outstanding Achievement in Child & Adolescent Psychiatric Research

Nathan A. Fox, Ph.D. Distinguished University Professor “My career has been spent examining the factors that are asso- Department of Human Development ciated with the development of psychopathology in children and Quantitative Methodology and adolescents. The importance of translational work cannot Neurosciences and Cognitive be over-emphasized. I find that to be true of my temperament Sciences Program work and my work on early adversity. Throughout my research University of Maryland, College Park career I have been fortunate to have outstanding collabora- 2007 Distinguished Investigator tors who have made this work exciting and fun. I am thrilled to receive this award and hope to continue my work in these areas and the translation of this work for policy and practice for years to come.”

Nathan A. Fox is a Distinguished Uni- Dr. Fox has completed research on the Along with fellow 2017 Ruane Award versity Professor in the Department of biological bases of social and emotional recipients Drs. Nelson and Zeanah, Dr. Human Development and Quantitative behavior, developing methods for assess- Fox is a Principal Investigator on the Methodology and the Neuroscience and ing brain activity in infants and young Bucharest Early Intervention Project. Cognitive Sciences Program at the Uni- children during tasks designed to elicit a This longitudinal study is the first (and versity of Maryland. He received a bach- range of emotions. His major focus has only) randomized clinical trial of foster elor’s degree in Political Science at Wil- been on the temperament of behavioral care intervention for infants and young liams College and his Ph.D. in Psychology inhibition, which confers a risk for devel- children who began life in institutions and Social Relations from Harvard Uni- opment of social anxiety in children. The under conditions of significant psycho- versity, and was a Postdoctoral Fellow research he has completed has identified social adversity. Drs. Fox, Nelson and in Cross-Cultural Child Development at factors that either reduce the likelihood Zeanah are also the authors of Romania’s Harvard. He is a founding member of the of development of anxiety or enhance its Abandoned Children: Deprivation, Brain National Scientific Council for the Devel- likelihood. This work focuses mainly on Development and the Struggle for Recovery oping Child and currently co-Scientific cognitive processes and Dr. Fox uses both (Harvard University Press, 2014). Director of this group. behavioral tasks and electrophysiology to assess individual differences in perfor- mance in children. “ Judith L. Rapoport, M.D., Chair of the Ruane Prize Selection Committee, said the studies by Drs. Fox, Nelson and Zeanah “document the behavioral and physiological abnormalities [of the Bucharest children] and include treatment intervention studies. While their collaborative studies were of great significance, it should be noted that all three of these investigators would be strong contenders for the Ruane Prize from their other studies independent of this particular collaboration.”*

*quote directed to all three ruane prize winners 16 ” ruane PRIZE for Outstanding Achievement in Child & Adolescent Psychiatric Research

Charles A. Nelson III, Ph.D. Professor of Pediatrics “It is an incredible honor to receive this prize. I have a and Neuroscience long-standing interest in how early experience impacts Professor of Psychology in Psychiatry early brain and behavioral development. I originally exam- Harvard Medical School ined this problem through the lens of typical development,

Professor of Education focusing most on the development and neural bases of face Harvard Graduate School of Education processing. Over the years this interest expanded to include

the impact of early adversity on brain-behavioral develop- Richard David Scott Chair in Pediatric Developmental Medicine Research ment; the study of infants at high risk for developing autism; Boston Children’s Hospital and most recently, how individual differences in processing facial emotion in infancy are associated with later psychopa- thology. Receipt of this award validates and affirms that the scientific problems I have elected to address over the past 25 years are significant and have the potential to positively impact the lives of tens of thousands of children.”

Charles A. Nelson III is a Professor of Pedi- Dr. Nelson’s research centers on a variety Along with fellow 2017 Ruane Award atrics and Neuroscience and Professor of of problems in developmental cognitive recipients Drs. Fox and Zeanah, Dr. Psychology in the Department of Psychi- neuroscience, including the development Nelson is a Principal Investigator on atry at Harvard Medical School, and Pro- of social perception; developmental tra- the Bucharest Early Intervention fessor of Education in the Harvard Grad- jectories to autism; and the effects of early Project and a co-author of Romania’s uate School of Education. He also holds adversity on brain and behavioral devel- Abandoned Children: Deprivation, Brain the Richard David Scott Chair in Pediat- opment. He chaired the John D. and Cath- Development and the Struggle for Recov- ric Developmental Medicine Research at erine T. MacArthur Foundation Research ery (Harvard University Press, 2014). Boston Children’s Hospital, and is Direc- Network on Early Experience and Brain Among his many honors, Dr. Nelson has tor of Research in the Division of Develop- Development, and served on the National received the Leon Eisenberg Award from mental Medicine. He received his under- Academy of Sciences (NAS) panels that Harvard Medical School, an honorary graduate degree from McGill University, wrote From Neurons to Neighborhoods, Doctorate from Bucharest University master’s degrees from the University of and more recently, New Directions in Child (Romania), has been a resident fellow Wisconsin and his Ph.D. from the Univer- Abuse and Neglect Research at the Rockefeller Foundation Bellagio sity of Kansas, all in psychology. Center (Italy), and has been elected to the American Academy of Arts and Sciences.

17 ruane PRIZE for Outstanding Achievement in Child & Adolescent Psychiatric Research

Charles h. Zeanah, JR., M.D. Mary Peters Sellars Polchow “I am deeply honored to receive the Ruane Prize with Chair in Psychiatry my colleagues. Our work has examined the long-term

Vice Chair for Child and effects of early deprivation and factors that enhance Adolescent Psychiatry children’s recovery following early adversity. This work

Professor of Psychiatry and Pediatrics has demonstrated the enormous potential of caregiv- ing to alter the course of children’s development and Director of the Institute for Infant the urgency of providing children with experiences that and Early Childhood Mental Health Tulane University School of Medicine promote healthy development.”

Charles H. Zeanah, Jr. is the Mary Peters Throughout his career, Dr. Zeanah has Dr. Zeanah has won numerous awards, Sellars Polchow Chair in Psychiatry and studied the effects of adverse early including the Irving Phillips Award for serves as Vice Chair for Child and Ado- experiences, including trauma, abuse, and Prevention (2006) and the Norbert and lescent Psychiatry, Professor of Psychi- neglect on young children’s development. Charlotte Rieger Award for Outstanding atry and Pediatrics, and Director of the He has been a leader in infant mental Scientific Achievement (2016) from the Institute for Infant and Early Childhood health, exploring attachment and attach- American Academy of Child and Adolescent Mental Health at the Tulane University ment disorders in conditions of extreme Psychiatry, the Blanche F. Ittelson Award School of Medicine. He received his bach- risk. He also has studied interventions for Research in Child Psychiatry (2009) elor’s degree in English and his M.D. from designed to enhance recovery following and the Agnes Purcell McGavin Award for Tulane University. He completed a pediat- exposure to adverse experiences and has Prevention (2015) from the American Psy- ric internship at the University of Virginia, published widely on these topics. With chiatric Association, and the Serge Lebovici a residency in general psychiatry at Duke fellow Ruane recipients Drs. Nelson and Award (2010) from the World Association University, and a fellowship in child and Fox, he has explored the effects of severe for Infant Mental Health. adolescent psychiatry and a research fel- early deprivation on brain and behavioral lowship at Stanford University. development in the Bucharest Early Inter- vention Project, and is co-author of Roma- nia’s Abandoned Children: Deprivation, Brain Development and the Struggle for Recovery (Harvard University Press, 2014).

18 Goldman-Rakic PRIZE for Outstanding Achievement in Cognitive Neuroscience

Trevor W. Robbins, Ph.D. Professor, Cognitive Neuroscience University of Cambridge “To receive the Patricia Goldman-Rakic Award is a very great honor that means a lot to me—not only because of my enor- Director mous admiration for Patricia and her approach to science, Behavioural and Clinical Neuroscience Institute which has inspired so much of my work, but also because of her inspirational encouragement and friendship.”

Trevor W. Robbins is a Professor of in control of action and thought, as well cognitive function with neural networks, Cognitive Neuroscience at the Univer- as motivation. He has been especially and is currently used in more than 700 sity of Cambridge and Director of the interested in the way chemical systems, institutes and clinical centers worldwide. Behavioural and Clinical Neuroscience including dopamine, norepinephrine, sero- Among several awards, Dr. Robbins was Institute. He received his bachelor’s, mas- tonin, and acetylcholine, mediate states the co-recipient of the Distinguished Sci- ter’s, and doctoral degrees in psychology such as mood and alertness to influence entific Contribution Award for 2011 from from the University of Cambridge. He is the functioning of these networks. He also the American Psychological Association a Fellow for the Royal Society. has pursued possible drug treatments for and recipient of the Gold Medal of the cognitive enhancement in patients with U.S. Society for Biological Psychiatry in Dr. Robbins’ research integrates psychiatric and neurodegenerative disor- 2017. In 2014 he shared the “Brain Prize” approaches from cognitive and behavioral ders ranging from attention-deficit hyper- of the Grete Lundbeck European Brain neuroscience with psychopharmacology. activity disorder and schizophrenia to Alz- Research Foundation. In a multi-disciplinary research program heimer’s and Parkinson’s diseases. involving both experimental animals and human patients, he has defined cognitive His interest in translational research and behavioral functions of neural net- began with his co-invention of the works linking the frontal lobes to other CANTAB computerized neuropsycholog- regions of the brain, such as the striatum, ical battery, which correlates measures of

“ Jack D. Barchas, M.D., Chair of the Goldman-Rakic Prize Selection Committee, said Dr. Robbins’ innovative and groundbreaking discoveries on the prefrontal cortex “have resulting in pioneering treatments relevant to various mental disorders. Like Pat Goldman-Rakic, Professor Robbins’ vigor and dedication to research and stellar productivity makes him ideal for this prize.” ”

19 previous outstanding achievement prizewinners lieber prize

1987 Benjamin S. Bunney, M.D. 1999 Salomon Z. Langer, Ph.D. 2010 Ming T. Tsuang, M.D., Ph.D., DSc. Yale University Compugen, Israel University of California, San Diego

1988 Philip Holzman, Ph.D. Richard Jed Wyatt, M.D. 2011 Carol A. Tamminga, M.D. Harvard University National Institute of Mental Health University of Texas Southwestern Medical Center at Dallas 1989 Timothy Crow, M.D. 2000 Nancy C. Andreasen, M.D., Ph.D. Oxford University, UK University of Iowa Joel E. Kleinman, M.D., Ph.D. National Institute of Mental Health 1990 Philip Seeman, M.D., Ph.D. William T. Carpenter, Jr., M.D. University of Toronto, Canada University of Maryland 2012 Michael O’Donovan, M.D., Ph.D. Cardiff University, Wales 1991 Patricia Goldman-Rakic, Ph.D. 2001 Solomon H. Snyder, M.D. Yale University The Johns Hopkins University Michael J. Owen, M.D., Ph.D. Cardiff University, Wales 1992 John M. Kane, M.D. 2002 Francine M. Benes, M.D., Ph.D. Albert Einstein College of Medicine Harvard University 2013 Marc G. Caron, Ph.D. Duke University Medical Center Herbert Y. Meltzer, M.D. 2003 Robin Murray, M.D., DSc Vanderbilt University King’s College London, Institute 2014 David L. Braff, M.D. of Psychiatry, UK University of California, 1993 Daniel R. Weinberger, M.D. San Diego School of Medicine National Institute of Mental Health 2004 Joseph T. Coyle, M.D. Harvard University Patrick F. Sullivan, M.D., 1994 Arvid Emil Carlsson, M.D.* FRANZCP University of Gothenburg, Sweden 2005 David A. Lewis, M.D. Karolinska Institute, University University of Pittsburgh 1995 Kenneth S. Kendler, M.D. of North Carolina, Chapel Hill Virginia Commonwealth University 2006 Jeffrey A. Lieberman, M.D. 2015 Robert Freedman, M.D. Columbia University 1996 Paul Greengard, Ph.D.* University of Colorado, Denver The Rockefeller University 2007 Eve C. Johnstone, M.D. Patrick McGorry, M.D., Ph.D University of Edinburgh, Scotland 1997 Göran C. Sedvall, M.D., Ph.D. FRCP, FRANCZP Karolinska Institutet, Sweden 2008 Irving I. Gottesman, Ph.D. Orygen and University University of Minnesota of Melbourne Lars Farde, M.D., Ph.D. Karolinska Institutet, Sweden 2009 Raquel E. Gur, M.D., Ph.D. 2016 Michael F. Green, Ph.D. University of Pennsylvania 1998 George K. Aghajanian, M.D. Stephen R. Marder, M.D. Yale University Ruben C. Gur, Ph.D. University of California, University of Pennsylvania Los Angeles Sarnoff A. Mednick, Ph.D.,Dr. Med. University of Southern California

*Recipient of the 2000 Nobel Prize in Physiology or Medicine.

20 maltz prize

Baer Prize 2011 Elena I. Ivleva, M.D. 2015 M. Camille Hoffman, M.D., MSCS University of Texas Southwest University of Colorado, Denver 2004 Jonathan Picker, M.D., Ph.D. Medical Center Harvard University Barnaby Nelson, Ph.D. Amanda J. Law, Ph.D. Orygen and University 2005 Takanori Hashimoto, M.D., Ph.D. National Institute of Mental Health of Melbourne University of Pittsburgh 2012 James T. R. Walters, M.D., Ph.D. Maltz Prize 2006 Lorna W. Role, Ph.D. Cardiff University, Wales Columbia University 2016 William P. Horan, Ph.D. 2013 Kafui Dzirasa, M.D., Ph.D. 2007 Jeremy Hall, M.D., Ph.D. Duke University Amanda McCleery, Ph.D. Edinburgh University, Scotland University of California, Nikhil M. Urs, Ph.D. Los Angeles 2008 Angus W. MacDonald, III, Ph.D. Duke University University of Minnesota 2014 Gregory Light, Ph.D. 2009 Daniel H. Wolf, M.D., Ph.D. University of California, San Diego/ University of Pennsylvania San Diego Veterans Affairs Department 2010 Stephen J. Glatt, Ph.D. State University of New York, Stephan Ripke, M.D. Upstate Psychiatric Genomics Consortium

21 colvin prize

Selo Prize 2002 Ronald Duman, Ph.D. Colvin Prize Yale University 1993 Robert M. Post, M.D. 2012 Eduard Vieta, M.D., Ph.D. Pennsylvania State Hospital Paul Grof, M.D., Ph.D. University of Barcelona, Spain University of Ottawa, Canada 1994 Jules Angst, M.D. Karen Dineen Wagner, M.D.,Ph.D. Psychiatric University Hospital, 2003 Robert M. A. Hirschfeld, M.D. University of Texas Medical Branch Zurich, Switzerland University of Texas Medical Branch, at Galveston at Galveston Myrna M. Weissman, Ph.D. 2013 Boris Birmaher, M.D. New York State Psychiatric Ross J. Baldessarini, M.D. University of Pittsburgh School Institute Harvard University of Medicine

1995 Claude de Montigny, M.D., Ph.D. Leonardo Tondo, M.D., M.S. Andrew A. Nierenberg, M.D. McGill University, Canada Cagliari University, Italy Harvard Medical School

1996 Wade Berrettini, M.D., Ph.D. 2004 Harold A. Sackeim, Ph.D. 2014 Wayne C. Drevets, M.D. University of Pennsylvania Columbia University Johnson & Johnson, Inc.

Elliot S. Gershon, M.D. Joseph R. Calabrese, M.D. Fritz A. Henn, M.D., Ph.D. University of Chicago Case University School of Medicine Cold Spring Harbor Laboratory, Ichan School of Medicine J. Raymond DePaulo, Jr., M.D. 2005 Jan A. Fawcett, M.D. at Mount Sinai The Johns Hopkins University University of New Mexico 2015 Michael Berk, Ph.D., MBBCh, 1997 Arthur Prange, Jr., M.D. Alan F. Schatzberg, M.D. MMed, FF(Psych)SA, FRANCZP University of North Carolna- Stanford University Deakin University Chapel Hill 2006 Lori L. Altshuler, M.D. L. Trevor Young, M.D., Ph.D., Charles B. Nemeroff, M.D., Ph.D. University of California, FRCPC Emory University Los Angeles University of Toronto

1998 Martin B. Keller, M.D. 2007 Helen S. Mayberg, M.D. 2016 Francis J. McMahon, M.D. Brown University Emory University National Institute of Mental Health

Julien Mendlewicz, M.D., Ph.D. 2008 Charles L. Bowden, M.D. Thomas G. Schulze, M.D. University of Brussels/ University of Texas Health Science Medical Center of the University Erasme Hospital, Belgium Center at San Antonio of Munich

Falcone Prize Mark S. George, M.D. Pamela Sklar, M.D., Ph.D. Medical University of South Icahn School of Medicine 1999 Frederick K. Goodwin, M.D Carolina George Washington University at Mount Sinai 2009 Lewis L. Judd, M.D., DSc (Hon.) Husseini K. Manji, M.D. University of California, San Diego National Institute of Mental Health Eric J. Nestler, M.D., Ph.D. 2000 Kay Redfield Jamison, Ph.D. Mount Sinai School of Medicine The Johns Hopkins University Bipolar Mood Disorders Prize A. John Rush, Jr., M.D. University of Texas Southwestern 2010 Lars Vedel Kessing, M.D., D.M.Sc. Medical Center at Dallas Copenhagen University Hospital, Rigshospitalet, in Denmark Robert H. Belmaker, M.D. Ben-Gurion University, Israel 2011 David J. Miklowitz, Ph.D. University of California, 2001 Hagop S. Akiskal, M.D. Los Angeles University of California, San Diego Carlos A. Zarate, M.D. William E. Bunney, Jr., M.D. National Institute of Mental Health University of California, Irvine

22 ruane prize

2000 Professor Sir Michael L. Rutter 2007 James F. Leckman, M.D. 2013 Jay N. Giedd, M.D. King’s College London, Institute Yale University National Institute of Mental Health of Psychiatry, UK 2008 Eric Andrew Taylor, M.D. 2014 Anita Thapar, M.D., Ph.D. 2001 Donald J. Cohen, M.D. King’s College London, Cardiff University School of Yale University Institute of Psychiatry, UK Medicine

2002 Judith L. Rapoport, M.D. 2009 Adrian C. Angold, M.D. 2015 BJ Casey, Ph.D. National Institute of Mental Health Duke University Medical Center Weill Cornell Medical College

2003 Leon Eisenberg, M.D. E. Jane Costello, Ph.D. Francisco Xavier Castellanos, Harvard Medical School Duke University Medical Center M.D. Child Study Center at NYU 2004 Magda Campbell, M.D. 2010 Terrie E. Moffitt, Ph.D. Langone Medical Center New York University Duke University King’s College London, 2016 John L. R. Rubenstein, M.D., Ph.D. C. Keith Conners, Ph.D. Institute of Psychiatry, UK University of California, Duke University San Francisco Avshalom Caspi, Ph.D. Rachel G. Klein, Ph.D. Duke University New York University King’s College London, 2005 Allan L. Reiss, M.D. Institute of Psychiatry, UK Stanford University 2011 Daniel S. Pine, M.D. 2006 David A. Brent, M.D. National Institute of Mental Health University of Pittsburgh School 2012 Daniel Geschwind, M.D., Ph.D. of Medicine University of California, David Shaffer, M.D. Los Angeles Columbia University Matthew State, M.D., Ph.D. Yale University goldman-rakic prize

2003 Solomon H. Snyder, M.D. 2009 Brenda Milner, CC, Ph.D. 2015 Amy F. T. Arnsten, Ph.D. The Johns Hopkins University McGill University, Canada Yale University

2004 Michael Posner, Ph.D. 2010 Robert C. Malenka, M.D., Ph.D. 2016 Earl K. Miller, Ph.D. University of Oregon Stanford University Massachusetts Institute of Technology Marcus Raichle, M.D. 2011 Michael E. Goldberg, M.D. Washington University Columbia University/ New York State 2005 Bruce S. McEwen, Ph.D. Psychiatric Institute The Rockefeller University 2012 Larry R. Squire, Ph.D. 2006 Joaquin M. Fuster, M.D., Ph.D. University of California, San Diego University of California, Los Angeles 2013 Karl Deisseroth, Ph.D. Stanford University 2007 Huda Akil, Ph.D. University of Michigan 2014 Richard L. Huganir, Ph.D. Johns Hopkins University 2008 Eric J. Nestler, M.D., Ph.D. School of Medicine Mount Sinai School of Medicine

23 Scientific Council

President Karl Deisseroth, M.D., Ph.D. James F. Leckman, M.D. Bryan L. Roth, M.D., Ph.D. Herbert Pardes, M.D. J. Raymond DePaulo, Jr., M.D. Francis S. Lee, M.D., Ph.D. Laura Rowland, Ph.D. Ariel Y. Deutch, Ph.D. Ellen Leibenluft, M.D. John L.R. Rubenstein, M.D., Ph.D. Vice President Emeritus Wayne C. Drevets, M.D. Robert H. Lenox, M.D. Bernardo Sabatini, M.D.,Ph.D. Floyd E. Bloom, M.D. Ronald S. Duman, Ph.D. Pat Levitt, Ph.D. Gerard Sanacora, M.D., Ph.D. Stan B. Floresco, Ph.D. David A. Lewis, M.D. Akira Sawa, M.D., Ph.D. Ted Abel, Ph.D. Judith M. Ford, Ph.D. Jeffrey A. Lieberman, M.D. Alan F. Schatzberg, M.D. Anissa Abi-Dargham, M.D. Alan Frazer, Ph.D. Kelvin Lim, M.D. Nina R. Schooler, Ph.D. Schahram Akbarian, M.D.,Ph.D. Robert R. Freedman, M.D. Irwin Lucki, Ph.D. Robert Schwarcz, Ph.D. Huda Akil, Ph.D. Fred H. Gage, Ph.D. Gary Lynch, Ph.D. Philip Seeman, M.D., Ph.D. Susan G. Amara, Ph.D. Aurelio Galli, Ph.D. Robert C. Malenka, M.D., Ph.D. Yvette I. Sheline, M.D. Stewart A. Anderson, M.D. Mark S. George, M.D. Anil K. Malhotra, M.D. Pamela Sklar, M.D., Ph.D. Nancy C. Andreasen, M.D.,Ph.D. Elliot S. Gershon, M.D. Husseini K. Manji, M.D., Solomon H. Snyder, M.D., Amy F.T. Arnsten, Ph.D. Mark A. Geyer, Ph.D. F.R.C.P.C. D.Sc., D.Phil. (Hon. Causa) Gary S. Aston-Jones, Ph.D. Jay N. Giedd, M.D. J. John Mann, M.D. Vikaas Sohal, M.D., Ph.D. Jay M. Baraban, M.D., Ph.D. Jay A. Gingrich, M.D., Ph.D. John S. March, M.D., M.P.H. Matthew State, M.D. Deanna Barch, Ph.D. David Goldman, M.D. Stephen Maren, Ph.D. Murray Stein, M.D., M.P.H. Jack D. Barchas, M.D. Joshua A. Gordon, M.D., Ph.D. Daniel Mathalon, Ph.D., M.D. John S. Strauss, M.D. Samuel H. Barondes, M.D. Elizabeth Gould, Ph.D. Helen S. Mayberg, M.D. J. David Sweatt, Ph.D. Carrie Bearden, Ph.D. Anthony A. Grace, Ph.D. Bruce S. McEwen, Ph.D. John A. Talbott, M.D. Francine M. Benes, M.D., Ph.D. Paul Greengard, Ph.D. Ronald McKay, Ph.D. Carol A. Tamminga, M.D. Karen F. Berman, M.D. Raquel Gur, M.D., Ph.D. James H. Meador-Woodruff, M.D. Laurence H. Tecott, M.D.,Ph.D. Wade H. Berrettini, M.D., Ph.D. Suzanne N. Haber, Ph.D. Herbert Y. Meltzer, M.D. Ming T. Tsuang, M.D., Ph.D.,D.Sc. Randy D. Blakely, Ph.D. Philip D. Harvey, Ph.D. Kathleen Merikangas, Ph.D. Kay M. Tye, Ph.D. Pierre Blier, M.D., Ph.D. Stephan Heckers, M.D. Richard J. Miller, Ph.D. Leslie G. Ungerleider, Ph.D. Hilary Blumberg, M.D. René Hen, Ph.D. Karoly Mirnics, M.D., Ph.D. Flora Vaccarino, M.D., Ph.D. Antonello Bonci, M.D. Fritz A. Henn, M.D., Ph.D. Bita Moghaddam, Ph.D. Rita J. Valentino, Ph.D. Robert W. Buchanan, M.D. Takao Hensch, Ph.D. Dennis L. Murphy, M.D. Jim van Os, M.D., Ph.D., Peter F. Buckley, M.D. Robert M.A. Hirschfeld, M.D. Charles B. Nemeroff, M.D.,Ph.D. MRCPsych Ed Bullmore, Ph.D. L. Elliot Hong, M.D. Eric J. Nestler, M.D., Ph.D. Jeremy Veenstra- William E. Bunney, Jr., M.D. Steven E. Hyman, M.D. Andrew A. Nierenberg, M.D. VanderWeele, M.D. Joseph D. Buxbaum, Ph.D. Robert B. Innis, M.D., Ph.D. Patricio O’Donnell, M.D., Ph.D. Susan Voglmaier, M.D., Ph.D. William Byerley, M.D. Jonathan A. Javitch, M.D.,Ph.D. Dost Ongur, M.D., Ph.D. Nora D. Volkow, M.D. Ty Cannon, Ph.D. Daniel C. Javitt, M.D., Ph.D. Steven M. Paul, M.D. Mark von Zastrow, M.D., Ph.D. William Carlezon, Ph.D. Dilip Jeste, M.D. Godfrey D. Pearlson, Karen Dineen Wagner, M.D.,Ph.D. Marc G. Caron, Ph.D. Ned Kalin, M.D. M.A.,M.B.B.S. Daniel R. Weinberger, M.D. William T. Carpenter, Jr., M.D. Peter W. Kalivas, Ph.D. Mary L. Phillips, M.D. (CANTAB) Myrna M. Weissman, Ph.D. Cameron S. Carter, M.D. Eric R. Kandel, M.D. Marina Picciotto, Ph.D. Marina Wolf, Ph.D. BJ Casey, Ph.D. Richard S.E. Keefe, Ph.D. Daniel S. Pine, M.D. Jared W. Young, Ph.D. Bruce M. Cohen, M.D., Ph.D. Samuel J. Keith, M.D. Robert M. Post, M.D. L. Trevor Young, M.D., Ph.D. Jonathan D. Cohen, M.D., Ph.D. Martin B. Keller, M.D. James B. Potash, M.D., M.P.H. Jon-Kar Zubieta, M.D., Ph.D. Peter Jeffrey Conn, Ph.D. John R. Kelsoe, M.D. Steven G. Potkin, M.D. Edwin Cook, M.D. Kenneth S. Kendler, M.D. Pasko Rakic, M.D., Ph.D. Members Emeritus Richard Coppola, D.Sc. James L. Kennedy, M.D. Judith L. Rapoport, M.D. George K. Aghajanian, M.D. Rui Costa, Ph.D., HHMI Robert M. Kessler, M.D. Perry F. Renshaw, M.D., Ph.D., Dennis S. Charney, M.D. Joseph T. Coyle, M.D. Mary-Claire King, Ph.D. M.B.A. Jan A. Fawcett, M.D. Jacqueline N. Crawley, Ph.D. Rachel G. Klein, Ph.D. Kerry J. Ressler, M.D., Ph.D. Frederick K. Goodwin, M.D. John G. Csernansky, M.D. John H. Krystal, M.D. Victoria Risbrough, Ph.D. Lewis L. Judd, M.D. Z. Jeff Daskalakis, M.D., Ph.D. Amanda J. Law, Ph.D. Carolyn B. Robinowitz, M.D. Kenneth K. Kidd, Ph.D.

24 25 I congratulate the

Outstanding Achievement Prizewinners

for their research accomplishments and

I join in admiration and gratitude

for the humanitarian achievements of

Doctors Without Borders/Médecins Sans Frontières (MSF)

Steve Lieber An Honorary Tribute to Constance Lieber Outstanding Mental Health Advocate

Constance E. Lieber transformed her family’s experience with significant mental illness into a life filled with meaning, purpose, and extraordinary helpfulness. A global champion of psychiatric research and a deeply caring and visionary philanthropist, Connie committed her life to alleviating the suffering caused by mental illness.

Her guiding light continues to inspire us as we work to make her dreams a reality.

With Deep Respect and Gratitude, The Pardes Humanitarian Prize Committee In Honor of Doctors Without Borders/Médecins Sans Frontières (MSF) 2017 Pardes Humanitarian Prize in Mental Health Recipient

Your transformative work providing mental health care as an integrated component of medical aid during natural and man-made emergencies and chronic crises has had a lasting and profound impact on individuals, families and the global community.

You have inspired us all to use our knowledge towards the greater good for all humanity.

With Deep Respect The Pardes Humanitarian Prize Committee The Essel Foundation

Congratulates the Distinguished

2017 Brain & Behavior Research Foundation

Outstanding Achievement Prizewinners and the

Pardes Humanitarian Prizewinner,

Doctors Without Borders/Médecins Sans Frontières (MSF) Alpine Woods Capital Investors, LLC

Congratulates the 2017 Pardes Humanitarian Prizewinner

Doctors Without Borders/Médecins Sans Frontières (MSF)

and the Distinguished Scientists who are recipients of the

Brain & Behavior Research Foundation

Outstanding Achievement Prizes Borrego Foundation

Congratulates

Doctors Without Borders/Médecins Sans Frontières (MSF)

and the

2017 Outstanding Achievement Prizewinners Congratulations to

Doctors Without Borders/Médecins Sans Frontières (MSF)

2017 Pardes Humanitarian Prizewinner

and to the

2017 Outstanding Achievement Prizewinners

Tamar and Milton Maltz

GBF is a Catalyst for Transforming Youth Mental Health

GBF is proud to support the Anne & Ronald Abramson Brain & Behavior Research Foundation as they continue to invest in the pursuit of meaningful advances and breakthroughs in scientific research through their grants and prizes programs.

Congratulations to the 2017 Award Recipients!

King & Spalding proudly Congratulates the recipients of the supports the Brain & Behavior Outstanding Achievement Prizes, the Research Foundation’s 30th Annual Pardes Humanitarian Prize in Mental International Awards Dinner. Health, and the Brain and Behavior Research Foundation for their extraordinary commitment in helping the mentally ill and their loved ones by supporting scientific research. We salute your dedication to alleviating the suffering caused by mental illness. Jack D. Barchas, MD Barklie McKee Henry Professor and Chair

Francis Lee, MD, PhD Mortimer D. Sackler, M.D. Professor of Molecular Biology in Psychiatry ; Vice Chair, Research kslaw.com Columbia Psychiatry

We extend our deep appreciation to the Warm congratulations to the WeBrain extend & Behaviorour deep Research appreciation Foundation to the Pardes Humanitarian Prizewinner, forBrain over & a Behaviorquarter century Research of grants Foundation that lead to Constance E. Lieber and to all the foradvances over a quarter and breakthroughs century of in grants scientific that research. lead to Outstanding Achievement Prizewinners. advances and breakthroughs in scientific research. Your continual dedication Congratulations to Dr. Herbert Pardes on the and work mean much to us. Congratulationsinaugural Pardes to Humanitarianall the prizewinners Prize. Dr. forPardes their has outstanding significantly achievements.influenced the course of research and clinical care of mental illness. Jeffrey A. Lieberman, M.D. Bonnie & Alan Hammerschlag Chairman, Department of Psychiatry, Columbia University Director, New York State Psychiatric Institute

Jeffrey A. Lieberman, M.D. Chairman, Department of Psychiatry of Columbia University Director, New York State Psychiatric Institute

In Memory of Walter W. Bundschuh

George & Joanne Bundschuh

Congratulations to the 2017 Award Recipients.

Marc Rappaport & Léa Dartevelle

Thank you to John and Suzanne Golden for all you do for the Brain & Behavior Research Foundation.

Jill and Sanford Sirulnick In Honor of Dr. Herbert Pardes

Gerald Modell

Steven J. Corwin, M.D. President and Chief Executive Officer and The Board of Trustees, Physicians, Administration, and Staff of NewYork-Presbyterian Hospital congratulate Doctors Without Borders/Médecins Sans Frontières Brain & Behavior Research Foundation’s Pardes Humanitarian Prize in Mental Health Award Recipient

NYP_JournalAd_BBRF_1017.indd 1 10/6/17 4:08 PM The Brain & Behavior Research Foundation is committed to alleviating the suffering caused by mental illness by awarding grants that will lead to advances and breakthroughs in scientific research.

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