Oral Antiviral Agents* Acyclovir Famciclovir Valacyclovir Brand

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SUPPORT DOCUMENT II: Oral Antiviral Agents* Acyclovir Famciclovir Valacyclovir Brand Zovirax® Famvir® Valtrex® Generic Yes Yes Yes Available Adult HSV HSV HSV Indications 1. Genital infection 1. Genital infection 1. Genital infection 2. Encephalitis 2. Encephalitis 2. Labialis 3. Mucocutaneous 3. Recurrent labialis VZV VZV VZV 1. Shingles 1. Shingles 1. Shingles 2. Chickenpox 2. Chickenpox 2. Chickenpox Immunocompromised Immunocompromised Immunocompromised Patients Patients Patients 1. Prevention of HSV 1. Recurrent 1. Treatment of HSV reactivation mucocutaneous/ or VZV (Cancer) (HIV and HSCT) genital (HIV) 2. CMV prophylaxis 2. Prevention of VZV 2. Prevention of HSV (HSCT) reactivation (HSCT) reactivation (HIV) 3. Treatment of disseminated HSV or VZV (cancer) 4. Treatment of suspected HSV or VZV encephalitis (cancer) 5. Treatment of episodic HSV infection (HIV) Pediatric HSV none HSV Indications 1. Genital infection 1. Labialis 2. Encephalitis 3. Mucocutaneous VZV 4. Neonatal 1. Chickenpox 5. Prevention of reactivation (HIV exposed or positive patients, HSCT) VZV 1. Shingles 2. Chickenpox 3. Acute retinal necrosis (HIV exposed or positive patients) Pediatric Age > 2 years old > 18 years old > 2 years old (neonatal indication) U.S. Dosage Oral Oral Oral Forms Capsule Tablet Caplets Tablet (suspension can be Suspension prepared from 500mg caplets) IV Powder Solution Disease 1. Renal impairment 1. Renal impairment 1. Renal impairment Related Concerns Dosage 1. Lactose intolerance Concerns Warnings 1. Acute renal failure 1. Acute renal failure 1. TTP/HUS 2. TTP 2. Acute renal failure 3. CNS (agitation, hallucination, encephalopathy) Pregnancy B B B Category Dosing BID BID QD Frequency (Chronic Suppressive HSV Therapy) Adult Half 3 hours 2–4 hours 2.5–3 hours Life *Based on FDA Prescribing Information. HSCT: Hematopoetic stem cell transplantation TTP: Thrombotic thrombocytopenic purpura HUS: Hemolytic uremic syndrome .

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THROMBOCYTOPENIA: OUTCOMES of VARICELLA in ADULTS 1Amber Arshad, 2Dr
IAJPS 2018, 05 (12), 14370-14373 Amber Arshad et al ISSN 2349-7750 CODEN [USA]: IAJPBB ISSN: 2349-7750 INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES http://doi.org/10.5281/zenodo.1976759 Available online at: http://www.iajps.com Research Article THROMBOCYTOPENIA: OUTCOMES OF VARICELLA IN ADULTS 1Amber Arshad, 2Dr. Shafia Masood, 3Dr. Zarwa Shahid 1FMH Collage of Medicine and Dentistry, Lahore-Pakistan 2Holy Family Hospital Rawalpindi 3House Officer, Jinnah Hospital Lahore Abstract: Objectives: The purpose of this research work is to elaborate the seriousness and rate of the low quantity of the platelets in the blood having relation with adult patients suffering of chickenpox. Methodology: This was a descriptive research work carried out in Mayo hospital Lahore and the duration of this research work was from January 2015 to March 2018 in the department of infectious diseases. In this study, record of the demographics, medical data, and blood & biochemical alterations created for each and every patient. The entry of this data carried out on a special organized form. Patients with previous background of CLD (chronic liver disease), drug addicts, HIV patients, blood abnormalities, or consumers of the wine were not the part of this research work. The count of the full blood with count of the platelet conducted with the help of an automated BCM (Beckman Coulter machine). The verification of the haematological results, the patients having low quantity of the platelet underwent PSE (peripheral smear examination). Results: One hundred and ten patients were the participant of this research work. The average age of the patients was 32.9 ± 9.7 years.
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Cutaneous Manifestations of HIV Infection Carrie L
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A Review of Cutaneous Manifestations in Newborn Infants
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Coagulopathy Secondary to Chicken Pox: a Case Report
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Secondary Syphilis with Chickenpox in an Adult
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NOTIFICATION of CHICKENPOX (Varicella) (An Acute, Viral Infection)*
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Guidelines for Evaluating Chickenpox-Like Rash in Recipients of Varicella Vaccine
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