Paleoradiologists Unravel the Secrets of Ancient Mummies

March 2018 Volume 28, Issue 3 Image courtesy of Sahar Saleem, MBBCH, MSc, MD of Sahar Image courtesy

ALSO INSIDE: LOOK AHEAD: Molecular Imaging R&E Foundation Reaches $17.5 Million Campaign Goal Radiology’s Winding Road to Diversity and Inclusion Technology Can Aid Healthcare Team Communication

RSNA 2018 Abstract Submissions Now Open — See Page 24

MARCH 2018 • VOLUME 28, ISSUE 3

FEATURES

EDITOR 10 Gary J. Whitman, MD R&E FOUNDATION CONTRIBUTING EDITOR Theresa C. McLoud, MD EXECUTIVE EDITOR Shelley L. Taylor MANAGING EDITOR Beth Burmahl STAFF WRITER Jennifer Allyn Paleoradiologists Unravel Mysteries of Ancient Mummies GRAPHIC DESIGNER Eriona Baholli-Karasek EDITORIAL ADVISORS 6 9 Mark G. Watson Executive Director Karena Galvin Assistant Executive Director Marketing and International Affairs Marijo Millette Director: Public Information and Communications EDITORIAL BOARD Gary J. Whitman, MD LOOK AHEAD: Molecular R&E Reaches $17.5 Million Chairman Imaging Campaign Goal Vahid Yaghmai, MD Vice Chairman Ezra Bobo, MD 12 15 Stephen D. Brown, MD Carlo Catalano, MD Daniel A. Hamstra, MD, PhD Maureen P. Kohi, MD Laurie A. Loevner, MD Theresa C. McLoud, MD Martin P. Torriani, MD Mary C. Mahoney, MD Board Liaison Radiology’s Winding Road to Technology Can Aid Healthcare 2018 RSNA BOARD OF DIRECTORS Diversity and Inclusion Team Communication James P. Borgstede, MD Chairman Mary C. Mahoney, MD Liaison for Publications and UP FRONT NEWS YOU CAN USE Communications 2 First Impression 20 Journal Highlights Bruce G. Haffty, MD Liaison for Science 4 Numbers in the News 22 Radiology in Public Focus Matthew A. Mauro, MD Liaison for Education 5 My Turn 23 Value of Membership Curtis P. Langlotz, MD, PhD Liaison for Information Technology 24 Annual Meeting Watch and Annual Meeting RADIOLOGY’S FUTURE Umar Mahmood, MD, PhD 25 Technology Forum Liaison for International Affairs 16 R&E Foundation Donors Vijay M. Rao, MD President Valerie P. Jackson, MD President-Elect

RSNA MISSION Follow us for exclusive news, The RSNA promotes excellence in patient care and healthcare delivery through education, annual meeting offers and more! research and technologic innovation. FIRST IMPRESSION

R&E Cohen Appointed Radiology Foundation Chair at Temple University Gary S. Cohen, MD, has been appointed chair of radiology Announces at the Lewis Katz School of Medicine at Temple University and radiologist-in-chief for Temple University Health System, New Education Philadelphia. A diagnostic radiologist with a subspecialty in vascular and Cohen Grant Program interventional radiology, Dr. Cohen joined Temple’s faculty in 1993. He most recently served as vice chair of diagnostic To address members’ rapidly changing imaging, section chief of vascular & interventional radiology educational needs, the RSNA Research and co-director of the Liver Tumor Treatment Program. & Education (R&E) Foundation’s Board of Trustees has developed a new education grant program that will take a fresh approach to how the Foundation Roentgen Nominations Now Open solicits applications and funds grants. The first of the new grants will be awarded in 2019. Nomination Deadline Nominations are being accepted for the RSNA Roentgen The program seeks to enhance April 2 Resident/Fellow Research Award, recognizing residents and the education of radiology faculty, fellows who have made significant contributions to their radiologists and radiology support departments’ research efforts as evidenced by presentations personnel through new educational and publications of scientific papers, receipt of research grants content, educational products or other or other contributions. innovative means for RSNA to share Nominations are limited to one resident or fellow per with its members. program in radiology, radiation oncology or nuclear medicine Grants will have specific topics of per year. The program director or department chair selects the interest representing the current and nominee for each program. future educational needs in radiology The RSNA Research & Education (R&E) and will offer the opportunity for large, Foundation provides an award plaque for multi-year, multi-institution grants of the department to display and a personalized up to $525,000. The educational grants award to present to the selected resident will allow for projects with smaller or fellow. The deadline for nominations budgets and timeframes, as well as those is April 2. Learn about the nomination focusing specifically on international process and see a list of past recipients at education. RSNA.org/Roentgen-Research-Award. The grants are: • Education Innovation Grant • Education Development Grant • Derek Harwood-Nash International Education Scholar Grant More details, including the specific Vinay Prabhu, MD, right, receives his 2017 topics of interest and requests for RSNA Roentgen Resident/Fellow Research applications, will be available in spring Award from Nancy Fefferman, MD. at RSNA.org/Grants-and-Awards. Time to Renew Your Image Wisely® Pledge Continue your commitment to safe Wisely logo to promote their participation imaging by renewing your Image Wisely® in the campaign. pledge or make a first-time promise to The Image Wisely website provides demonstrate your awareness about adult updated news on radiation safety, regu- radiation protection. lations and standards, and access to free Each year, those who renew their radiation safety cases to assess your under- pledges at ImageWisely.org will receive a standing of radiation safety concepts and College of Radiology, the American Soci- dated certificate validating their com- award continuing education credits. ety of Radiologic Technologists and the mitment to the campaign. Facilities with The Image Wisely campaign is a joint American Association of Physicists in current pledges can download the Image partnership of RSNA, the American Medicine.

2 RSNA News | March 2018 RSNA Partnership with DuPage Medical Group Helps Staff Better Serve Members

An RSNA partnership with DuPage attended the Medical Group helps new RSNA staff tours. members understand radiologists’ “We appreciate responsibilities so that they can, in turn, DuPage Medical RSNA staff tours of DuPage Medical Group are scheduled throughout 2018. better support RSNA members. Group and their “From a radiologist’s perspective, it is For the past several years, new RSNA staff for giving their time to speak with beneficial to interact with RSNA staff and staff have had the opportunity to tour RSNA staff about what radiologists do offer them a glimpse of what a radiologist’s the outpatient radiology centers of and what they need to provide high-qual- day looks like,” Dr. Shetty said. “This DuPage Medical Group, which has ity patient care,” said Sally Nikkel, assis- helps RSNA staff understand what is locations around RSNA headquarters tant executive director, RSNA finance and important to members so they can develop in Oak Brook, IL. Staff receive detailed administration. programming and activities that support tours of the imaging centers and speak RSNA member, Rajit S. Shetty, MD, our educational and clinical needs.” with radiologists and technologists about of DuPage Medical Group, also speaks Tours are scheduled throughout 2018 their expertise. So far, 130 staff have with the staff and answers questions. for new and established employees.

RSNA Members Earn Advanced Quality Certificates Four physicians received Advanced Level Quality Certificates from RSNA in 2017, bringing the total number of recipients to 20 since the first certificates were awarded in 2014. Earning the certificate requires successful completion of Quality Essentials Certificate Courses in four domains: Quality Improvement in Your Practice, Staff and Patient Safety, Customer Satisfaction and Radiologist Performance Improvement; as well as exhibition of a Quality Storyboard at an RSNA annual meeting as a primary author. (Please note, Quality Storyboards will be renamed Quality Improvement Reports beginning in 2018. The guidelines for these submissions will remain the same.) To learn more about the RSNA Quality Improvement Certificate Program, including the Advanced Level Quality Certificate program, go to RSNA.org/Quality-Improvement-Certificate-Program.

Name Institution Quality Storyboard Title Suhny Abbara, MD University of Texas A Comprehensive CT Radiation Dose Reduction and Protocol Southwestern Standardization Program in a Complex, Tertiary Hospital System Medical Center Using Iterative Phantom and Clinical Testing and a Novel Web-based Information Distribution System Alan M. Kantor, MD Lincoln Medical & Adapting the Universal Protocol in a Diagnostic Radiology Mental Health Center Department to Help Prevent Wrong Patient, Wrong Site, and (Bronx, New York) Wrong Examination Events Colleen H. Neal, MD University of Improving Breast MRI Wait Times: A Model for Transitioning Newly Michigan Health Implemented Diagnostic Imaging Procedures into Routine Clinical System Operation

Ben C. Wandtke, MD University of Closing the Loop: A Radiology Follow-up Recommendation Rochester Medical Tracking System Center Wang Awarded RANZCR Gold Medal Shih-chang Wang, MD, was awarded the 2017 gold medal at the recent Royal Australian and New Zealand College of Radiologists (RANZCR) annual meeting. A recognized expert in liver cancer therapy, Dr. Wang served as the Parker-Hughes Professor of Diagnostic Radiology at the University of Sydney, Australia, and as head of breast radiology at Westmead Breast Cancer Institute, in Westmead, Australia, before retiring in 2013. He also established the National Breast Screening Program in Singapore. Wang (right)

March 2018 | RSNA News 3 FIRST IMPRESSION

Apply Now for RSNA Editorial Fellowships Numbers in the News Applications are being accepted for the RSNA William R. Eyler Editorial Fellowship and the RSNA William W. Olmsted Editorial Fellowship for Trainees. The fellowships offer the opportunity to work with Radiology 17.5 Editor David A. Bleumke, MD, PhD, in Madison, WI, The number, in millions, or RadioGraphics Editor Jeffrey S. Klein, MD, in Burl- raised by the RSNA ington, VT. The Eyler fellowship lasts three weeks and Research & Education the Olmsted fellowship lasts one week. Foundation during its five- Each fellow will also visit the Publications Depart- year fundraising campaign. ment at RSNA Headquarters in Oak Brook, IL. The Read more on Page 9. Eyler Fellow will work with the RadioGraphics editorial team at RSNA 2018. Apply by May 1 to be considered for the William R. Eyler Editorial Fellowship and April 1 for the William W. Olmsted Editorial Fellowship for Trainees. To learn more and to apply, visit 15 RSNA.org/RSNA_Editorial_Fellowships.aspx. Percent of both medical school graduates and graduate medical education trainees who are minorities. Read more about diversity and inclusion in radiology on Page 12.

Juergen K. Willmann, MD, professor of radiology In Memoriam at the Stanford University School of Medicine, died Jan. 8 in Palo Alto, CA. He was 45. 1896 Recognized for his work in targeted contrast The year the first radio- microbubbles, Dr. Willmann was working on the graphs of mummies were first clinical imaging trials in humans, in which produced. Since then, the the microbubbles were used to detect breast and role of imaging has become ovarian cancer and target the delivery of drugs. increasingly critical to Dr. Willmann completed his medical degree at paleoradiologists investi- Albert Ludwig University of Freiburg, Buchenbach, gating these ancient relics. Germany. He completed his residency at the Read more on Page 10. University of Zurich in Switzerland. Willman After completing his residency, Dr. Willmann became an assistant professor and clinical attending physician at the University of Zurich. He and his wife, Amelie Lutz, MD, came to Stanford for research fellowships. He was recognized for his work in cancer detection and imaging technologies with a 2017 Distinguished Investigator Award from the Academy for Radiology & Biomedical Imaging Research. Dr. Willmann published studies in Radiology and served as RSNA faculty at several RSNA annual meetings.

LETTERS TO THE REPRINTS AND ADVERTISING March 2018 • Volume 28, Issue 3 Postmaster: Send address corrections or Contents of RSNA News EDITOR PERMISSIONS [email protected] Published monthly by the Radiological changes to: RSNA News, 820 Jorie Blvd., copyrighted ©2018, RSNA. [email protected] [email protected] Lisa Lazzaretto Society of North America, Inc. Oak Brook, IL 60523-2251 RSNA is a registered trademark 1-630-571-7837 fax 1-630-571-7829 Assistant Director: 1-630-590-7724 fax 820 Jorie Blvd., Oak Brook, IL Non-member subscription rate is $20 per of the Radiological Society of SUBSCRIPTIONS Corporate Relations 60523-2251. Printed in the USA. year; $10 of active members’ dues is North America, Inc. [email protected] 1-630-571-7818 allocated to a subscription of RSNA News. 1-888-600-0064 1-630-590-7770

4 RSNA News | March 2018 My Turn: Radiology Embarks on a New Era in Publishing

BY DAVID BLUEMKE, MD, PHD Improved Delivery of Digital Content and New Print Format Ten years ago, we predicted that Radiology Our current production model is designed would transition from a hardcopy journal to an around a monthly print issue. If you receive online publication. Yet our concept of “online” our monthly table of contents by email, the list was monolithic — limited by the technology of 30 or more articles scrolls almost endlessly of the time — simply meaning content would off the bottom of the largest “plus size” mobile be available on the internet. Today the world is phone. polylithic. We receive information on multiple We will start delivering organized, weekly platforms, and the way we consume informa- content for our mobile readers. We have already tion has become more personalized. streamlined notifications. Further improvement In this context of information flux, Radiology will continue over the next 12 months and must determine how to best get useful medical mobile offerings will extend to enhanced use of and scientific information to imaging physi- podcasts and social media. An updated print cians and scientists in our field. In the coming format in 2018 is aimed to provide readers with Dr. Bluemke is editor of months we will take several steps to improve an improved visual experience. Radiology and a professor in the the information that you receive through these Department of Radiology at new initiatives. Images in Radiology the University of Wisconsin – Our authors generate some of the most inter- Madison (UW – Madison) Targeted Editorials esting and innovative medical images in the School of Medicine and Public If you are a general radiologist but need to world. Beginning in 2018, Images in Radiology Health. In 1997, he became keep up with developments throughout the will be a new journal feature, highlighting the clinical director in the MRI imaging field, your reaction to an article on state-of-the-art radiologic imaging depicting division of the Department of the brain connectome may be bewilderment at interesting and relevant diagnoses. Submissions Radiology at Johns Hopkins the density and complexity of the science. Our for this feature are being solicited at this time. Hospital. In 2008, he became scientific authors are super-specialized experts a tenured senior investigator for in their domains. The technical requirements Subspecialized Journals the NIH and the radiologist-in- of their fields are enormous. As a result, our Radiology delivers high-quality content for our chief of Radiology and Imaging authors write articles that appeal to highly readers by being very selective regarding the Sciences at the NIH Clinical specialized reviewers. Thus, we have started to material that is published. About 3,000 original solicit “targeted editorials” for key articles that research articles are submitted each year; only Center. He was also a senior we publish. These editorials will briefly explain about 5 to 10 percent are accepted. A substan- investigator at the National the significance of the research and highlight its tial portion of rejected material is excellent Institute of Biomedical Imaging strengths and weaknesses. quality but pertains to a specialty radiologist. and Bioengineering (NIBIB) To that end, the RSNA Board has approved the and an adjunct investigator Faster Publication Times development of three new subspecialty journals for the National Heart, Lung Authors have always struggled with publishing on the topics of imaging of cancer, cardiotho- and Blood Institute (NHLBI). information in a timely fashion. Even the U.S. racic disease, and artificial intelligence/machine A longtime member of RSNA, federal government has realized that the time learning in imaging. Each new online-only Dr. Bluemke served as deputy to publish and release information from clinical journal will have its own editor and editorial editor of Radiology from 1993 trials is too long. NIH guidelines specify that board of specialists, and planning for the jour- to 1997. results must be reported within 12 months of nals is underway. The journals will launch in concluding a trial. Yet, data analysis alone may 2019. take many months and publishing in Radiology I look forward to continuing the tradition may take many more. We are highly committed of excellence that Radiology is known for while to reducing time to publication, while provid- ensuring the journal meets the needs of today’s ing a forum for the world’s leading research in radiologists. the field of radiology.

March 2018 | RSNA News 5 FIRST IMPRESSION

LOOK AHEAD Molecular Imaging

BY VIKAS KUNDRA, MD, PhD

Molecular imaging is bringing novel approaches to diagnose and monitor disease. It has already proven successful in clinical practice. New advances will enable molecular characterization and should enable evaluation of therapy not only at the level of detection and response, but also to assess delivery and mechanistically to assess whether a therapy is affecting its intended target. This opens up fresh and exciting avenues for imaging.

VIKAS KUNDRA, MD, PHD, is professor and director of molecular imaging in the Department of Radiology, University of Texas MD Anderson Cancer Center with a joint appointment in the Department of Cancer Systems Imaging. He received his MD and PhD from Harvard University. He trained at Harvard Medical School’s Brigham and Women’s Hospital. He is a fellow of the Society of Body Computed Tomography-Magnetic Resonance Imaging and Distinguished Investigator of the Academy of Radiology Research.

Dr. Kundra practices as a clinical radiologist focused on body imaging primarily using CT and MRI. He has authored multiple clinical and basic/translational science papers and secured grants from federal sources including the National Institutes for Health, the Department of Defense and the National Science Foundation.

6 RSNA News | March 2018 “Molecular imaging requires teams of experts such as those skilled in biology, chemistry, physics and instrumentation.” VIKAS KUNDRA, MD, PhD

What is Molecular Imaging? Broadly, molecular imaging may be defined as non- or minimally-invasive assessment of biologic and pathologic Kundra of Dr. Images courtesy processes based on molecular or functional analysis. This may include both molecularly targeted and non-targeted imaging. Although there may be some debate regarding the exact definition, the practical clinical outcome is adding analysis of molecular/functional alter- Multimodal imaging of ovarian cancer. DM-dual-Gd-ICG liposomal nanoparticles, which have high ation to anatomic changes in order to MR relaxivity due to gadolinium chelates on their surface and within them, and can be used for near improve differential diagnosis and to infrared fluorescence (NIR) due to incorporated indocyanine green, were injected intravenously two monitor therapy. days earlier. Intraperitoneal human ovarian tumor xenografts (dotted lines or arrows) enhanced by MR (left, axial view) and demonstrated NIR signal (left bottom, coronal view). This should enable Non-Targeted Imaging presurgical planning by MR and NIR-guided surgical resection. K, kidneys; I intestines. An example of non-targeted molecular imaging performed clinically is diffusion weighted MRI, which is ative charge keeps it from crossing conversion may be associated with the increasingly playing a role in detecting the cell membrane; thus, it becomes degree of tumor dedifferentiation or tumors and evaluating response. It is entrapped in the cell and accumulates. stage and that it may be able to detect based on assessing molecular motion Inflammatory cells have high metabolic early response to therapy even when by MRI. Diffusion weighting depends rates and 18F-FDG PET imaging is used 18F-FDG PET imaging is not informa- on the b-value, which reflects the for infection/inflammation imaging. As tive. Because multiple metabolites and strength and timing of the magnetic outlined in the Warburg effect, cancer even molecularly targeted agents may gradients. At mid b-values, tissue-level cells tend to utilize the less efficient be hyperpolarized, this technology has motion can be evaluated and highly anaerobic pathway to generate energy promise to affect a variety of imaging cellular structures such as tumors can more than do normal cells, and thus schema. be detected. Newer techniques include require more input glucose, the primary Molecularly-targeted imaging has studying faster motion using low fuel source. 18F-FDG PET imaging has been in place in nuclear medicine b-values, such as afforded by intravoxel been used to image a variety of, but departments for some time. One incoherent motion (IVIM) for evaluating not all, tumors and their response to example is peptide-based imaging parameters such as D and f akin to tis- therapy. of somatostatin receptors. 111In-oc- sue diffusion coefficient and perfusion With the advent of hyperpolarization treotide-based imaging has been a fraction, as well as studying slower imaging, it has become possible to nuclear medicine workhorse. The motion using high b-values to limit perform biochemistry in vivo, including gamma particle emission by the 111In T2 “shine-through.” These techniques assessing late events in glycolysis. label enables imaging by single pho- are being evaluated as to whether Hyperpolarization can increase the sig- ton emission computed tomography they enable improved detection and/or nal from atoms in molecules 10,000- to (SPECT). Octreotide mimics soma- response evaluation. 100,000-fold, but lasts only seconds tostatin and binds to somatostatin to minutes for the great majority. Due receptors including types 2 and 5. Molecular-targeted Imaging to the tremendous signal gain, not only Newer labels include 68Ga and 64Cu to An example of targeted molecular can the input molecule be imaged, enable PET for higher resolution imag- imaging is 18F-fluorodeoxyglucose but also its metabolic products. For ing. Newer peptides include octreotate (FDG). The beta particle emission by example, a key inflection point in gly- for more selectivity for somatostatin the 18F label enables imaging by posi- colysis is pyruvate which sits at the receptor type 2. These advances and tron emission tomography (PET). FDG decision point of whether to undergo advances in scanner design and fusion or fluorodeoxyglucose mimics glucose anaerobic respiration and produce lac- systems such as PET-MR will enable and enters the cell through glucose tate or undergo aerobic respiration. In improved detection and localization of (GLUT) transporters and then becomes tumors, the rate of pyruvate to lactate molecular signatures. Combining func- phosphorylated. The phosphorylated conversion tends to be higher than in tional and anatomic information can form is not a good substrate for the normal cells. In animal models there enable quantification of receptors as next enzyme in glycolysis and its neg- has been a suggestion that the rate of shown in animal models.

March 2018 | RSNA News 7 FEATURE

Promising New Techniques disease and has been proposed to be Oncology is beginning to define tumors used to assess the efficacy of disease beyond just the site of the organ of interventions. origin to also include alterations in gene expression for which molecular Gene Therapy Applications imaging may make significant contri- New therapeutic techniques require butions. Fusion imaging can help guide new imaging approaches. Gene therapy biopsy. This is particularly important and cellular therapy have found recent Images courtesy of Dr. Kundra of Dr. Images courtesy for obtaining tissue for understanding success but are limited by an inability genomic, metabolomic and proteomic to visually localize and quantify gene alterations in lesions before and after expression or cellular localization with- targeted therapy. This information aids out biopsy. This may be approached in understanding if the intended target using reporter imaging where a gene of the therapy was indeed altered and for imaging is inserted into the gene whether this resulted in the expected therapy vector. Commonly, this insert clinical effect. Biopsy is impractical results in the production of a protein for whole subject evaluation, whereas, that can itself be imaged or can bind to molecularly targeted imaging should an imaging agent. Most commonly the enable evaluation of pathologic imaging agent is a radiopharmaceutical heterogeneity, such as in a primary since nuclear medicine techniques tumor and among it and metastases have the greatest sensitivity, but MRI in order to select appropriate targeted may follow in the future. It should be therapies. These may include immu- possible to insert an appropriately Imaging of gene expression. Mouse tumors notherapies in the future. New tracers designed gene for imaging into a made to express a human somatostatin variety of gene therapy vectors so receptor type 2 (WT)-based reporter or a are becoming available/approved, such signaling deficient variant (SD) were imaged as for prostate cancer imaging and that several vectors or cell types can after injection of a radiolabeled somatostatin for imaging somatostatin receptors, be imaged. In addition, it should be analogue. A reporter that does not perturb which should increase reimbursement. possible to link the gene for imaging to the cell such as by initiating signal transduc- Such tracers should benefit from new a therapeutic gene so that imaging can tion is desirable. The preferred signaling hybrid technologies such as PET/MR help measure expression of the thera- deficient version was imaged similar to wild peutic gene. Ideally, the reporter imag- type but was muted in initiating cellular sig- since anatomy and pathology in many naling. Vec, negative control tumor without important target organs such as in the ing gene system will enable imaging reporter expression; expected radiotracer pelvis, liver, and brain can be better in patients, is small in order to fit into excretion is seen via the kidneys (K). delineated by MR than CT. In addition, vectors, is non-immunogenic, and does improved hardware and software such not depend on its function for imaging as time of flight imaging and solid state so as not to disturb normal cell func- detectors for PET and faster gradients tion. These reporters are becoming for MR are resulting in faster scanners available, such as signaling deficient with improved image quality resulting reporters based upon somatostatin in increased subject throughput and receptor type 2. This type of imaging improved lesion detection as well as would further enable gene and cellular interpretation. therapies. Tau and amyloid beta plaque-imaging agents were recently approved Team Approach for imaging of neurodegenerative Molecular imaging requires teams of diseases such as Alzheimer’s disease. experts such as those skilled in biology, Such techniques have the potential for chemistry, physics and instrumentation. early detection even before there are It requires development from bench overt clinical signs and for monitoring to bedside and expertise in commer- efficacy of preventive and therapeutic cialization to bring the innovations to strategies, assuming that these or patients. Molecular imaging has already developing imaging agents visualize a been established in the clinic and relevant surrogate of clinical disease. new approaches suggest potential for In this case, the degree of tau or improving current imaging and strong amyloid beta deposition is presumed potential to develop new approaches to reflect the degree of Alzheimers for meeting future needs.

8 RSNA News | March 2018 R&E Raises $17.5 Million to Fund Radiology’s Future The entire radiology community rose to the challenge and reached the $17.5 million goal to fund RSNA Research & Education (R&E) Foundation grants for radiology researchers and educators.

The Foundation launched Inspire- Since the launch, the Foundation has Innovate-Invest: The Campaign for provided $15 million to 340 innovators Funding Radiology’s Future® in 2013 in radiology research and education. with the ambitious goal of raising $17.5 Moreover, the Foundation’s grant pro- million. The effort was led by Cam- gram has helped many young radiologists paign co-chairs R. Nick Bryan, MD, pursue careers in research, helping to PhD, David C. Levin, MD, and the late maintain the intellectual leadership in William G. Bradley, Jr., MD, PhD. The imaging and image-guided therapies, co-chairs worked tirelessly to promote earn the respect in the medical commu- Bradley the Campaign and demonstrate the value nity and improve patient care, said N. of giving to the Foundation. In fact, past Reed Dunnick, MD, Board of Trustees grant recipients report that for every dol- chairman. lar awarded by the Foundation they have For example, Robert R. Flavell, MD, earned an average $50 more from other PhD, received a 2015 RSNA Research sources, including the National Institutes Fellow Grant, and his work has led to the of Health. development of multiple new positron Platinum Centennial Pathfinder emission tomography and hyperpolarized Phan T. Huynh, MD, was an early and 13C MRI tracers for imaging the tumor staunch supporter. As chair of the R&E Fund microenvironment. “This initial funding helped Development Committee, Dr. Huynh proudly propel me into my first academic position and Bryan champions the Foundation’s mission throughout helped greatly in writing several papers, obtaining the radiology community. “I feel so much grati- extramural funding and starting my own labora- tude to be in our amazing profession and I feel I tory,” Dr. Flavell said. owe it to my mentors who shaped my career to Past R&E grant recipient Colin P. Derdeyn, give back,” he said. MD, chair and departmental executive officer of Campaign donors who have made multi-year the Department of Radiology at the University commitments represent every area of radiology, of Iowa, committed to the Campaign as a Silver including 65 Centennial Pathfinders who made Centennial Pathfinder. “Receiving the Siemens personal donations, generous private practice Medical Solutions/RSNA Research Fellow Grant groups and corporate supporters. Campaign 23 years ago had a profound impact on my donors were bound by a common thread — the career. It opened up a lot of opportunities,” Dr. Levin understanding that radiology research performed Derdeyn said. “I’m grateful to be in a position to by radiologists is the most important way radiol- give back.” ogists can support the future of the specialty. With the support of these and many more “Our practice, as well as private practice Campaign donors the Foundation will continue groups across the country, are beneficiaries to lead in funding radiology research and educa- of research and education in the form of the tion well into the future. future development of cutting-edge radiology “On behalf of the Foundation Board of Trust- techniques, interventions and technologies,” ees, thank you to all of our donors for your said Brian D. Petersen, MD, of Inland Imaging, investment in advancing the field of radiology Professional Services. “Our contribution to the through your support of innovative research and Inspire-Innovate-Invest Campaign was the most education projects,” Dr. Dunnick said. direct way we could show our support for this If you are inspired and would like to learn process.” The practice made a 10-year commit- more about Funding Radiology’s Future, contact ment toward the Campaign. Liten DeNaut, assistant director, fund develop- The Campaign’s impact is already evident. ment, at 630-368-3744 or [email protected].

“On behalf of the Foundation Board of Trustees, thank you to all of our donors for your investment in advancing the field of radiology through your support of innovative research and education projects.” N. REED DUNNICK, MD

March 2018 | RSNA News 9 FEATURE

Paleoradiologists Unravel the Secrets of Ancient Mummies

BY BETH BURMAHL When the ancient Egyptians mummified their dead, they did so without recording details about the process, which was intended to preserve the body so the soul could reclaim or “recognize” it after death. And while the ancients sought to keep the process a secret, radiologists — or more specifically, paleoradiologists — are using imaging to unwrap the mysteries of mummification and reveal astonishing details about the people hidden beneath the linen wrappings.

“The Egyptians left no writings about the While a bone chip process for mummies, and yet they wrote inside his skull had about most aspects of their lives,” said fueled suspicion that Sahar N. Saleem, MBBCH, MSc, MD, Tut had been mur- a radiologist at Cairo University, Egypt, dered, the CT scan of who spoke about paleoradiology at RSNA the mummy in 2005 2017. “They wanted to keep it a secret.” determined that the But since the x-ray was discovered in bone was detached 1895, paleoradiologists have been unlock- from a broken neck Saleem ing those ancient Egyptian secrets, one vertebra during the image at a time. autopsy executed by Captured in 1896, the first radiographs Howard Carter in 1925. Tut, as it turns of mummies were helpful, but were often out, died of malaria and complications fuzzy and did not reveal the specific from a broken leg (also detected by CT) details researchers were seeking. When CT and likely walked with a cane. More than A CT image of the trunk of the Golden mummy was introduced in the 1970s, it provided 160 canes were found in his tomb. (circa 1000 BC) located at the Egyptian Museum in Cairo shows a rounded amulet of high density a level of detail that made CT the method Dr. Saleem also helped solve the mur- inside the mummy's torso. of choice for examining mummies. der of Ramesses III, the Egyptian pharaoh “X-rays can only see two planes, but who lived from 1190–1070 BC. When CT scanning can differentiate among the Dr. Saleem, with renowned Egyptologist various types of bone and soft tissue,” said Zahi Hawass, PhD, and other researchers, Dr. Saleem, who studied scanning mum- first scanned the mummy in 2012, they mies in Canada and has been studying determined that Ramesses III died when royal mummies of the New Kingdom in someone slit his throat with a sharp knife. Egypt since 2005. When reassessing the pharaoh’s CT Multi-detector CT scanning of ancient scans in 2015, Drs. Saleem and Hawass human remains has helped researchers determined that Ramesses III had sus- understand ancient cultures, revealed the tained injuries from different types of secrets of mummification and provided a weapons, suggesting that more than one deeper level of information on the origin assailant was involved. The researchers and natural history of diseases. And more detail the story of Ramesses III in their recently, 3-D printing technology has 2016 book, “Scanning the Pharaohs.” allowed radiologists to create 3-D printed “Imaging also revealed that Ramesses’ models of amulets and jewelry inside the big toe was chopped off,” Dr. Saleem said. bodies of the mummies. “From what we discovered, it was likely a very bloody scene.” On the cover: A 3-D CT image of the face of CT Solves Ancient Murder Mysteries In researching the mummification Seti I mummy shows subcutaneous packing In recent years, Dr. Saleem and colleagues process, Dr. Saleem determined that sub- material in three regions: around the nose and have used CT to help solve two myste- cutaneous packing was used in mummies mouth (naso-labial fold), the cheeks and the rious deaths that took place in ancient temporal regions. including those of Tutankhamun and Egypt, including that of the world’s most Ramesses III. In the process, the ancients famous pharaoh, King Tutankhamun. inserted resins and other fillers under the

10 RSNA News | March 2018 All images courtesy of Sahar Saleem, MBBCH, MSc, MD of Sahar images courtesy All

A 3-D CT image of the trunk of the mummy of pharoah Ramesses III (1190-1070 BC) shows four statues made of faience representing the four sons of Horus, an ancient Egyptian deity. CT identified the statues as the body of man with different heads: human, jackal, falcon and baboon.

skin to preserve the looks of the even for fertilizer,” Dr. Saleem said. dead — essentially an early form of The discovery of the x-ray a short cosmetic surgery. Egyptians believed time later gave researchers the ability preserving the looks of a dead per- to see beneath the cloth wrappings son would help the soul more easily and piece together the individual find its body. stories — adding value and dignity “We discovered that the ancient to each person’s life. Egyptians must have had substan- Dr. Saleem, who does much tial knowledge of anatomy as well of her research at the Museum of as considerable surgical skills,” Dr. Cairo, spends her time in the muse- A CT image of the left foot of Saleem said. um’s basement, which is filled with Ramesses III shows a partially sealed artifacts that have never been amputated left big toe. The bony Ensuring the Legacy of Egyptian studied. The museum, the only one edges are sharp without signs of Mummies in the world with a CT scanner, has attempted healing (short arrow). Along with the royals, ancient some 160,000 pieces on display and The ancient embalmers replaced Egyptians also mummified millions regularly exhibits those identified by the missing toe with a linen-made A 3-D CT image of a pot of bodies, including those of com- CT. The museum also has a database prosthesis (long arrow) and (circa 500 BC) from the placed several metallic amulets mon people, Dr. Saleem said. After of information related to imaging basement of the Egyptian th (Eye of Horus) at the foot region Museum in Cairo. The wall a massive excavation in the 19 the artifacts, she said. to promote magical healing for the of the pot is virtually cut Century, mummies were so plentiful During the RSNA 2017 session, after life (arrowheads). open to show that it contains in Europe and America that they Gerald J. Conlogue, MHS, RT, a full mummy of a neonate. were often unwrapped publicly and presented on his experience in field Pot burial of young children at private parties held by the elite. imaging of mummies in their tombs, was common in ancient Dr. Saleem called the events “freak Egypt, especially for middle while Andrew J. Nelson, PhD, and lower social classes. shows.” discussed his work on micro CT “Thousands of mummies were in archaeology. ground up and used as powder and

“We discovered that the ancient Egyptians must have had substantial knowledge of anatomy as well as considerable surgical skills.” SAHAR N. SALEEM, MBBCH, MSC, MD

March 2018 | RSNA News 11 FEATURE

Women now comprise up to 50 percent of both medical The Windingschool graduates Road and graduate medical toeducation traineesDiversity

Underrepresented minorities (URMs) only comprise 15 percent of both medical school graduates and graduate and Inclusionmedical education in trainees Radiology

BY JENNIFER ALLYN The number of female trainees in radiology has remained Women now comprise upstagnant to 50 percent over the of past both eight medical years. While the numberschool graduatesof women and graduate and minoritiesmedical education graduating trainees from medical school has risen

in recent years, the number ofFemale these representation students has only who risen 0.3 choose percent increase radiology as a specialty has remained static. per year in radiation oncology over the past 20 years. Underrepresented minorities (URMs) only comprise 15 percent of both medical school graduates and graduate medical education traineesFor URMs, there is an 8 percent representation in radiology andIn 9 percent this first in radiationof a series oncology of articles trainees. about of practicing radiologists and radiation

24 to 26% of practicing radiologists diversity and inclusion in radiology, oncologists, according to the Associa- and radiation oncologistsThe number are women. of female trainees in radiology has remained stagnant over the past eightDiagnosticRSNA years. radiologyNews talked ranks with 17th forexperts representation who offer of tion of American Medical Colleges, the — Association of American Medical Colleges womenWomen among now comprise the 20 largest up to 50training percent programs. of both medical theirWomen perspectives now comprise about when up to and 50 percenthow of bothnumber medical of female radiology trainees has schoolthe schoolgraduatescall for graduates diversity and graduate andandWomen medical inclusiongraduate education now medicalin the comprise trainees educationremained up trainees to stagnant 50 percent over the of past both eight medical Diagnostic radiology ranks 18th in total URM resident Female representation hasenrollment onlyfield risen originated among 0.3 percent the and 20 largest discussincreaseschool training the challenges graduatesprograms. andyears graduate and shows medicalonly a subtle education 0.3 percent trainees per year in radiation oncologyUnderrepresentedand over obstacles the past minoritiesto 20 bringing years. (URMs) more only diverse comprise 15 increase per year in radiation oncology Women now comprise up to Underrepresented minorities (URMs) only comprise 15 0.3% percentviewpoints of both medicalinto radiology. school graduates and graduate over the past 20 years. 50% of both medical school medicalpercent education of traineesboth medical school graduates and graduate Discussions about diversity and inclu- Since 1995, there has been minimal graduates andFor graduate URMs, there medical is an 8 percent medical representation education in radiology traineesUnderrepresented minorities (URMs) only comprise 15 and 9 percent in radiation oncologysion go trainees.all the way backpercent to 1955 whenof both medicalimprovement school in graduatesminority trainee and repre graduate- education trainees. The number of female trainees in radiology has remained medical colleges acknowledgedmedical the education lack sentation trainees in radiology, with 8 percent of stagnantof African-Americans over the past eight years.in medicine. By the students in general radiology training and The number of female trainees in radiology has remained Diagnostic radiology ranks 17thlatestagnant for1960s representation and over early the 1970s, pastof eight the years.number 9 percent in radiation oncology, according women among the 20 largestFemaleof training African-American representation programs. has onlystudents risen 0.3 in percentmedical increase to 2016 statistics cited by Dr. Lightfoote. Female representation has only risen perschools year in radiation had risen oncology from overThe2.4 thepercent number past 20 to years. 6.3 of femaleThese trainees slowly inrising radiology numbers has are aremained

0.3% 0.3% per year in radiationDiagnostic oncology radiology ranks 18thpercent.Female in total In representationURM1974, resident the numberstagnant has onlyof women overrisen 0.3 the percent pastsource eight increase of concern years. for Curtiland Deville, over the past 20 years. enrollment among the 20 largestper training year in programs. radiation oncology over the past 20 years. Forin URMs, medical there school is an 8 percent was 22.4 representation percent. in radiologyMD, associate professor of radiation and 9 Bypercent the inlate radiation 1990s oncology and early trainees. 2000s, oncology and molecular radiation sci- 0.3% thereFor were URMs, calls there for diversityis anFemale 8 percent across representation representationthe ences, in has radiologyJohns only Hopkins risen Medicine, 0.3 percent Balti -increase board at medical schools and not just in more, MD, and clinical director, radiation Diagnosticand radiology9 percent ranks in radiation 17thper for representation year oncology in radiation trainees. of oncology over the past 20 years. womenterms among of race the and20 largest gender. training programs. oncology, Johns Hopkins Kimmel Cancer Today, diversity and inclusion are top- Center at Sibley Memorial Hospital, Minorities comprise 15% of both medical school Diagnostic radiology ranks 18th in total URM resident of-mindDiagnostic imperatives radiology for ranksleaders 17th of medicalfor representation Washington, of D.C. graduates and graduate medical education trainees. enrollment among the 20 largest training programs. schoolswomen where among students the 20 Forare largest treating URMs, training an there programs. is an“The 8 percent number representationof diverse individuals in radiology 0.3% increasingly diverse Americanand 9 population,percent in radiationis increasing oncology in medical trainees. schools but for accordingDiagnostic to Johnson radiology B. ranks Lightfoote, 18th in MD, total URMreasons resident that are becoming increasingly a diagnosticenrollment radiologist among the and 20 medical largest trainingdirec- programs.clearer, radiology is not a specialty of 8% of radiology trainees and 9% of tor for the Department of Radiology at interest for many of them or is not seen radiation oncology trainees are minorities. Diagnostic radiology ranks 17th for representation of the Pomona Valley Hospital Medical Cen- as offering benefits as unique as other spe- women among the 20 largest training programs. Diagnostic radiology ranks 17th for ter, Pomona, CA. cialties,” Dr. Deville said. representation of women among “As medicine moves toward more the 20 largest medical training programs. patient-centered care, notDiagnostic just in radiol radiology- Overcoming ranks 18th Misconceptions in total URM resident ogy, but in all specialties,enrollment the workforce among Whilethe 20 many largest of the training barriers toprograms. increasing Diagnostic radiology ranks 18th in total needs to reflect the patients we serve — the number of medical students in radiol- minority resident enrollment among ogy are the same for all students — such the 20 largest medical training programs. not only in clinical care, but in all aspects 0.3%of medicine, including research and as lack of early exposure to the specialty healthcare access discussions,” Dr. Light- — there are common misconceptions that *Statistics provided by Johnson B. Lightfoote, MD foote said. specifically affect women and minority Women now comprise up to 50 per- medical students. cent of both medical school graduates Two common misconceptions about and graduate medical education trainees, the specialty are that radiologists rarely while minorities comprise just 15 percent, interact with patients and have limited according to a 2015 study in JAMA Inter- opportunities to provide direct service to nal Medicine. the community. According to Dr. Deville, For these groups, radiology and radia- a driving factor for many African-American tion oncology rank near the bottom of the and Latino students who are considering largest residency specialties. While women medical school is whether or not they will make up approximately 24 to 26 percent be able to give back to their community.

12 RSNA News | March 2018 Editor’s Note: This is the first in a series of RSNA News articles on diversity and inclusion in radiology. The second article will address how radiology leaders can promote diversity in the field.

“We acknowledge that the numbers of women and minorities in radiology won’t change overnight and that these issues will require sustained attention for years to see meaningful change.” MATTHEW BUCKNOR, MD

Lightfoote Deville Kulkarni Lu Bucknor

“Community and family play strong At the University of Chicago, the roles in these students’ lives,” Dr. Deville Radiology Committee on Diversity was said. “Radiology is not seen as having formed to support a university priority to enough community interaction that would increase diversity in every department. benefit the lives of their families and The committee did ad hoc work in 2012 neighbors.” that revealed a huge gender gap in radiol- A lack of female role models and a per- ogy trainees. Female resident representation ception that radiology is a male-dominated was less than 20 percent and, in one year, profession, have also been noted, especially zero out of eight residents were women. hindering the ability of female medical stu- To help drive more interest, the com- dents to envision a radiology career path. mittee hosts the Radiology Expo, a large- Finally, bias, often unconscious or scale lecture and hands-on annual event implicit, has been documented in several that exposes all medical students to radiol- studies as occurring in radiology, especially ogy, hopefully early enough in their edu- when considering promotions, whereby an cation so that they can make an informed equally qualified candidate is ranked lower decision about the specialty. for a position because of gender, race or “We decided to be more proactive to ethnicity. introduce medical students to radiology, While these misconceptions and barriers instead of waiting for them to find us may seem overwhelming, both Drs. Dev- during their rotations,” said Radiology ille and Lightfoote said that if the need for Committee on Diversity member Kirti improved diversity resonates within every Kulkarni, MD, associate professor of practice, training hospital and university, radiology at the University of Chicago. there can be a culture shift that can posi- The Radiology Expo has drawn a diverse tively affect both the clinical and business roster of attendees. Over the past year, sides of radiology. more than 70 students from nine differ- “Developing goals and strategies to ent universities across the midwest have improve workforce diversity will require attended with more than 33 percent being an investment by our profession, our aca- women and 22 percent being minorities. demic leaders and our practices,” Dr. Dev- “Mentoring programs and outreach ille said. “It is time to expose women and events, like the Radiology Expo, will con- underrepresented minorities to radiology tinue to help equal out diversity across the earlier in their schooling and then engage board, along with support from leader- and support their career growth once they ship,” said Zheng Feng Lu, PhD, co-chair enter the specialty.” of the Radiology Committee on Diversity and a professor of radiology, clinical diag- Radiology Initiatives Promote Diversity nostic physicist at the University of Chi- While larger, U.S. efforts are moving for- cago. “I hope that those who benefit from ward slowly, universities across the country these activities will find the energy and have adopted initiatives to help radiology desire to pay it forward to the generation departments integrate strategies to facili- after them.” tate a more diverse and inclusive staff. Continued on next page

March 2018 | RSNA News 13 FEATURE

From left to right: Kirti Kulkarni, MD, Maryellen Giger, MD, PhD, Carina Yang, MD, Etta Pisano, MD, and Zheng Feng Lu, PhD. Drs. Kulkarni, Giger, Yang, and Lu are key members of the University of Chicago Committee on Diversity, pictured here at the Radiology Expo. Dr. Pisano was the keynote speaker at the inaugural Radiology Expo in 2016.

Continued from previous page In 2015, the University of California, Change Will be Gradual San Francisco, (UCSF) formed their With increased awareness and several Radiology and Biomedical Imaging Diver- creative and effective programs driving sity Committee that builds upon the interest in radiology training, what are the university’s system-wide commitment to next steps to further ensuring diversity and promoting diversity and inclusion. representation in radiology? UCSF offers the Research Initiative to “Next steps should include meeting promote Diversity in Radiology (RIDR), potential students where they are, which is a summer program that provides high online,” Dr. Bucknor said. “Utilizing webi- school, college and medical students from nars to address misconceptions that stymie diverse and underrepresented backgrounds these students and creating online mentor- with a paid internship to work with a fac- ships that showcase a radiology career path ulty researcher. Its Radiology Elective to could make a huge difference in raising promote Diversity in Radiology (REDR) interest and securing recruitment.” program offers a travel stipend for medical Reaching students early in their careers students outside of UCSF to visit the four will be increasingly pivotal, Dr. Lightfoote major hospitals that make up its system said. and explore the opportunities available. “Change does not come easy in medi- “We acknowledge that the numbers cine, but early success inspires continued of women and minorities in radiology won’t innovation,” Dr. Lightfoote said. “Placing change overnight and that these issues will diversity, representation and inclusion into require sustained attention for years to see the core policies and missions of medical meaningful change,” said Matthew Bucknor, organizations and universities will allow us MD, chair of the committee and assistant to achieve workforce diversity that meets the professor in residence in musculoskeletal needs of our patients and ourselves.” radiology at UCSF.

14 RSNA News | March 2018 Technology Can Aid Healthcare Team Communication

BY LYNN ANTONOPOULOS With continuous advancements in technology, radiologists have access to more tools than ever to combat breakdowns in communication with referring physicians and to ultimately play a greater role in improved patient care. The virtual consult application is particularly important in the emergency department because it cuts through the problem of accessing help and can deliver an immediate benefit to the patient. “This is also especially useful where experts may not be in the area where patients live. Their access to care is not limited by geographic boundaries,” Dr. Wintermark said. Bridging the Data Divide As a result of advancements in artificial intelligence, future radiologists will move toward a more data-driven environment Annette J. Johnson, MD; Andrew B. During RSNA 2017, Max Wintermark, with more clinically useful work and less Rosenkrantz, MD; Tarik K. Alkasab, MD, PhD; MD, professor of radiology and chief of mechanical work related to interpreting and Max Wintermark, MD, participated in a neuroradiology at Stanford and reporting. Data-driven image acqui- panel to explore communication strategies sition, data extraction, data-assisted inter- between radiologists and referring physicians. University, moderated a panel of presenters focused on identifying costly commu- pretation and data-oriented reporting are nication gaps between radiologists and all part of the future of radiology. referring physicians while broadening Using a wealth of data from a wide variety awareness of some creative and strategic of sources, radiologists can turn reporting ways radiologists are leveraging technol- into the optimal tool for advancing ogy to be more active in patient care after patient care. The challenge is to bridge the imaging. divide between imaging data and clinical Often overwhelmed with heavy work- data, presenters said. The answer may loads, radiologists may be hesitant to be to employ technology to gather rich assume additional responsibilities related data from all sources and provide layered to conveying test results and ensuring reporting that includes details more useful proper follow-up with patients. Yet those to referring physicians and more under- activities can play an important role in standable to patients, they said. not only carefully interpreting images and Maintaining a Personal Connection WEB EXTRAS making recommendations but also acting View a video of Dr. Wintermark discussing Although technology can increase com- interacting effectively with referring physicians as a safe, patient-centered back-up system munication, it can also be a barrier in the digital age at RSNA.org/News. and ensuring that actionable results are between radiologists and their clinical not overlooked. colleagues. It has the potential to lead Virtual Connections to de-personalization during care. Dr. Among the creative methods highlighted Wintermark said the key to incorporating were a virtual consult application and technology effectively is striking the right virtual rounds. Each follow the traditional balance, providing the patient access to model of a group of specialists meeting to expertise while retaining a familiar con- review patient films and discuss the course nection with a trusted provider. of care. However, through these virtual “Though the patients do not generally meetings, the teams can use available see radiologists, radiologists see the technologies to overcome the challenge of patients, and the patients are the center gathering specialists in one place. Instead, of our concerns — prioritized above all they may teleconference from separate else,” Dr. Wintermark said. “IT tools are locations and accomplish the same care goals. used to better serve the patient behind the film.”

March 2018 | RSNA News 15 RADIOLOGY’S FUTURE

RESEARCH & EDUCATION FOUNDATION DONORS

The RSNA Research & Education Foundation thanks the following donors for gifts made December 2, 2017 through January 4, 2018.

Vanguard Program Visionary Donors Companies supporting endowments and term funding for named grants. The following individuals are recognized for cumulative lifetime donations.

RUBY VISIONARY ($100,000) Marilyn & Ronald B. Schilling, PhD

PLATINUM VISIONARY ($25,000) Joseph H. Introcaso, MD, DMD Drs. Matthew & Patricia Mauro Bayer HealthCare Patrick A. Turski, MD $50,000 Corine A. Yee, MD & Michael T. Oliver, MD A Vanguard Member since 2004 GOLD VISIONARY ($15,000) Anonymous Mandip Gakhal, MD Kumaresan Sandrasegaran, MD Dr. Alvin Lee & Carol Sue Schlichtemeier Guerbet $25,000 SILVER VISIONARY ($10,000) A Vanguard Member since 1989 Mark O. Bernardy, MD BRONZE VISIONARY ($5,000) Mara G. & Steven H. Brick, MD Visionaries in Practice Peter L. Davis, MD Steven C. Gross, MD A giving program for private practices and academic departments. Michele H. Johnson, MD Paul T. Khoury, MD SILVER LEVEL ($25,000) Joe C. Leonard, MD Jamie & Thomas R. McCauley, MD

University Radiology Group, East Brunswick, NJ

BRONZE LEVEL ($10,000) Individual Donors Donors who give $1,500 or more per year qualify for the RSNA Presidents Circle. Their names are shown in bold face.

$10,000+ Marilyn J. Goske, MD & Nick & Jean Bryan Richard A. Rudick Carolina Radiology Associates, LLC, Myrtle Beach, SC Marilyn & Ronald B. Schilling, PhD In honor of Dorothy I. Bulas, MD Shirley S. Yang, MD, MBA & Joseph H. Introcaso, MD, DMD Andrew Yang, MSEE, MD Drs. Vincent & Laura Mathews In memory of Henry N. Wagner Jr., MD In memory of William G. Bradley Jr., MD, PhD Radiant Imaging, Inc., Arcadia, CA $5,000 – $9,999 Theresa C. McLoud, MD Anton N. Hasso, MD Dr. Alvin Lee & Carol Sue Schlichtemeier Hedvig Hricak, MD, PhD, DrHC & Alexander Margulis, MD, DSc, DrHC Suzanne J. Smith, MD & Ciril J. Godec Robert L. Kagan, MD & Bonnie Barnett Renate L. Soulen, MD & Richard Soulen Drs. Matthew & Patricia Mauro In memory of Patricia F. Borns, MD Carol & Richard L. Morin, PhD Anne C. Roberts, MD & $1,500 – $2,499 John E. Arnold, MD Leslie & Bibb Allen Jr., MD Donald A. Turcke, MD Jack G. Andersen, RT Deborah & Patrick A. Turski Family Fund Shirley Baron, PhD Corine A. Yee, MD & In memory of Richard L. Baron, MD Michael T. Oliver, MD Martha & Carlos Bazan III, MD In memory of Thomas F. Oliver Claire E. Bender, MD In memory of May & William Yee Mark O. Bernardy, MD Pamela Bisset, MD & $2,500 – $4,999 Robert R. Bisset, MD Anonymous Andy Christensen, BS Teresita L. Angtuaco, MD, FACR & Navya Dasyam, MBBS & Edgardo J. Angtuaco, MD, FACR Anil K. Dasyam, MD Martha & James Borgstede, MD Michaele & Burton Drayer, MD

16 RSNA News | March 2018 YOUR DONATIONS IN ACTION

Towards an Early Detection of Coronary Artery Bypass Graft Failure: A Computational Fluid Dynamics Approach Based on CT and 4-D flow MRI

Thanks to a 2017 Agfa HealthCare/RSNA Research Scholar Grant, Laura Jimenez-Juan, MD, will investigate the use of a computational fluid dynamics method based on CT angiography and 4-D flow MRI data for the early detection of coronary artery bypass graft (CABG) failure. “If our method is successful, it will allow early noninvasive assessment of coronary graft performance and could change the postoperative management of CABG patients,” Dr. Jimenez-Juan said.

Kelly V. Mayson & Perry G. Pernicano, MD, FACR Ronald J. Cocchiarella, MD Wendy J. Hanafee, MD Bruce B. Forster, MD C. Douglas Phillips, MD Daniel T. Cohen, MD Craig E. Hancock, MD Mandip Gakhal, MD David R. Piwnica-Worms, MD, PhD Martin I. Cohen, MD Gail C. Hansen, MD & Juris Gaidulis Faye C. Laing, MD Thomas Pope, MD & Karen & Steven M. Cohen, MD Thomas W. Hash II, MD Jamie & Thomas R. McCauley, MD Jennifer Cranny, MD Patricia E. Cole, MD, PhD Mizuki & Hiroto Hatabu, MD, PhD Michael P. Recht, MD Sherry & Joseph G. Craig, MD Linda A. Heier, MD Dr. Lee F. & Mrs. Donna B. Rogers Michael M. Raskin, MD, JD, MBA Arthur R. Crampton, MD Bernice E. Hoppel, PhD Frank J. Rybicki, MD, PhD Dean A. Genth & Gary W. Swenson, MD Aine M. Kelly, MD & Mukbil H. Hourani, MD Kumaresan Sandrasegaran, MD Ingrid E. & Stephen R. Thomas, PhD Paul P. Cronin, MBBCh Ann Yoshida & Milton W. Hummel, MD Karen & Michael A. Sullivan, MD Kris J. Van Lom, MD Brenda S. Foreman & Niamh & Gerard Hurley, MD Linda J. Warren, MD Richard D. White, MD Anthony J. De Raimo, MD Janice J. Hwang, MD Vera & J. Frank Wilson, MD Stephen M. Wilks, MD Robert L. Delapaz, MD Andrea C. Itskovich, MD Sally & James E. Youker, MD Robert G. Dixon, MD Tae Iwasawa, MD, PhD $500 – $1,499 Basak E. Dogan, MD Edward F. Jackson, PhD Anonymous (2) $300 – $499 Therese Suarez & Kei Doi, MD, PhD Richard H. Jenkins, MD In honor of Shyam K. Joshi Anonymous (2) Philip J. Dubois, MD Bonnie N. Joe, MD, PhD Doris Bate, MD In memory of Bingquan Lin, MD Hugh H. Eaglesham, MD Shawn R. Jones, MD In honor of Ruth J. Guttmann, MD M-Hachemi Aboun, MD Edward A. Eikman, MD Lester Kalisher, MD Victoria & Adejimi O. Adeniji, MD Douglas K. Ewing, MD Peter H. Kalkman, MD Michael N. Brant-Zawadzki, MD Faten Al-Douri, MBChB Mark E. Farnham, MD Anoop H. Karna, MD Nick & Jean Bryan Shahid R. Ali, MD & Mrs. Mehwish Ali Heather & Dana B. Fathy, MD, PhD Maria & Dennis Kay, MD In memory of William G. Bradley Jr., Kenneth S. Allen, MD Marcial Q. Favila, MD Donald R. Kennard, MD MD, PhD Marc J. Alonzo, MD Scott I. Fields, MD Ramin Khorasani, MD Ruth C. Carlos, MD, MS & Fernando A. Alvarado Sr., MD Amy M. Fowler, MD, PhD Paul T. Khoury, MD Gordon T. Lawless, MD Charles Ambelang, MD Walter R. Fowler, MS Angela & Donald R. Klein, MD Karen Chen, MD & James Chen, MD Steven M. Amberson, MD Susan J. Frank, MD & Thorsten Kohler, MD Chamaree Chuapetcharasopon, MD & George Antaki, MD Michael J. Sternschein, MD Paul C. Koutras, MD Somkiet Chuapetcharasopon, MD Sandeep S. Arora, MBBS Lindy Aboody-Freeman & Sherrill & Kenneth L. Kraudel, MD Marian U. & Melvin E. Clouse, MD Karen Jernstedt & Neil J. Freeman, MD Dan F. Kreider, MD Peter L. Davis, MD A. James Barkovich, MD Angela M. Fried, MD & Cheryl S. & Jeffry S. Kriegshauser, MD Shigeru Ehara, MD Catherine E. Beal, MD C. Stephen Djedjos, MD Richard T. Kubota, MD Julia R. Fielding, MD & Alberto C. Benedicto, MD Jeffrey L. Friedman, DO Laraine & Stanley D. Kurisko, MD The RSNA Keith P. Mankin, MD Ali A. Benkhaled, MD Nancy A. Gadziala, MD Timothy J. Lach, MD R&E Foundation In memory of Rosemary Fielding Jeffrey R. Gambach, MD Paulo M. Bernardes, MD Andrea Laghi, MD provides the Jessica & W. Dennis Foley, MD Royce J. Biddle, MD Robert C. Game, MD Brandon J. Langlinais, MD Evan K. Fram, MD Richard H. Blair, MD James D. Geihsler, MD Jeffrey C. Lee, MD research and David J. Giles, MD Byron J. Bohnn, MD Daghild Dencker & Julie S. Lee, MD Jonn-Terje Geitung, MD development that Hannah & Lawrence R. Goodman, MD Marian E. Bonner, MD Al Leighton, MD Mercedes & Miguel Gelman, MD Alan C. Hartford, MD, PhD Elissa S. Brebach, MD & Greg Brebach Robert Lenobel, MD keeps radiology David S. Gierada, MD Fredina & John S. Hashim, MD Mara G. & Steven H. Brick, MD Ellen & Robert M. Lerner, MD, PhD Maryellen L. Giger, PhD & in the forefront of Mary & Peter R. Hulick, MD, MS Rick L. Brittain, MD Sherrian N. Leslie, MBBS, DMRD Charles C. Giger, MD medicine. Support In memory of Peter V. Hulick, MD Roger E. Brockman, MD Alena Levit, MD In memory of Richard L. Baron, MD Hero K. Hussain, MD & Yousif Albustani Loretta Higgins & Manuel L. Brown, MD Barbara T. & Richard A. Levy, MD your future— Philip W. Gilroy Jr., MD Michele H. Johnson, MD Sara R. & Stephen D. Brown, MD Ann E. Lewandowski, MD Michael Ginsburg, MD donate today at Diana T. Jucas, MD & Srini Vasan Karen & Steven R. Brown, MD Jean & Joel E. Lichtenstein, MD Phyllis Glanc, MD Mel L. Kantor, DDS, MPH Thomas C. Bryson, MD Regina L. Liebman, MD RSNA.org/Donate. Timothy C. Goertzen, MD Lorraine L. La Roy, MD James J. Buchino, MD Gregory M. Lim, MD Phyllis & Barry B. Goldberg, MD Joe C. Leonard, MD Joseph D. Calandra, MD In honor of Brooke Jeffrey, MD Steven C. Gross, MD Lilian Leong, MD & C.H. Leong, MD Juan J. Cevasco, MD Cynthia & Paolo P. Lim, MD Maria T. Gualtieri, MD Ann M. Lewicki, MD Christopher K. Chan, MD & Mrs. Erin Chan James T. Link, MD John J. Guido, MD Jeffrey E. Magnuson, MD Balasundaram Chandra-Sekar, MD Gregory D. Linkowski, MD Marina A. Gutwein, MD Kenneth R. Maravilla, MD Allen M. Chen, MD Mathias Lipski, MD Ehsan A. Haider, MBBCh Carol & Gordon McLennan, MD Yale Yueh-Ju Chung, MD Ryan L. Lo, MD Lee D. Hall, MD Cristopher A. Meyer, MD Crandon F. Clark Jr., MD Raj M. Paspulati, MD Seiki Hamada, MD, PhD Winston F. Clarke, MD Continued on next page

March 2018 | RSNA News 17 RADIOLOGY'S FUTURE

Continued from previous page Mary K. & David B. Underwood, MD Frits H. Barneveld Binkhuysen, MD Alessandra F. de Souza Alves, BDS David A. Valenti, MD Laura M. Baron, MD Abbey Delaney Rob H. van der Rijt, MD Alice Barrios Duarte, MD Jimmy Della Mark E. Lockhart, MD Gert J. Van Der Westhuizen, MBChB Sabine Batsche Liten & Eric DeNaut Deborah G. Longley, MD Franz E. Velarde, MD Jan Beger In memory of William G. Bradley Jr., Vinay D. Luthra, MD Bala Tripura S. Voruganti, MD Svetlana & George M. Benashvili, MD MD, PhD William F. Lytle Jr., MD Dieter Wallentin, MD Pamela & Geoffrey T. Benness, MD Thaworn Dendumrongsup, MD James D. MacGibbon, MD Andrew C. Warheit, MD Carlo Biagini, MD Vilma A. Derbekyan, MD Vaishali & Ajay R. Malpani, MD Catherine Wells, MD, PhD Alex Bibbey, MD Shobha P. Desai, MD & Thomas Mammen, MD, FRCPC James D. Wells III, MD Begona Bisteni Paresh B. Desai, MD Stuart H. Mansfield, MD Harold A. White, MD Ernesto Blanco, MD Valerie Descoux Laurie R. Margolies, MD Beth E. Whiteside, MD & Jory Block Laurent Desloques, MD, PhD Helga & Borut Marincek, MD Michael Whiteside, MD Marie-Claude Bluteau, MD Bhaswanth Dhanireddy, MD Janine R. Martyn, MD Susan & Gary J. Whitman, MD Brian T. Bolinger, MD Marco Di Girolamo, MD Tara C. Massini, MD Christopher T. Wickman, MD Carmen M. Bonmati, MD & Gina A. Di Primio, MD Matthew B. McClain, MD Thomas Witomski, MD Benjamin N. Conner, MD Facundo N. Diaz, MD, PhD Charles H. McDonnell III, MD Myron M. Wojtowycz, MD Nikos P. Bontozoglou, MD Ramiro Diaz Sr., MD Elizabeth G. McFarland, MD Paul W. Wong, MD Mitra B. Boodram, MD Richard Kinh Gian Do, MD, PhD Maria-Gisela Mercado-Deane, MD Edward L. Yang, MD Christopher J. Bosarge, MD Darrin Dodge A. Carl Merrow Jr., MD Nina & Ramana V. Yedavalli, MS, MD Michele Bove, MBChB Maria Thea V. Dolar, MD Brian J. Moffit, MD Stephen Ying, MD Lisa & Jonathan Breslau, MD Ronald J. Dolin, MD Christopher P. Molgaard, MD Shahnaz & Amir A. Zamani, MD Christian Broennimann Henrique J. Donato, MD Courtney & Christian E. Morel, MD Lori & Steven Zieber, MD Brenda J. Brown, MA, ARRT Bernardo A. Doria Sr., MEng Kambiz Motamedi, MD Stephanie Zeskind, MD & Arturo Brunetti, MD Dave Douwes Brannon R. Moye, MD Adam J. Zuckerman, DO Dennis Brunton Marcus Drews James F. Murphy, MD Jen Bryant, PhD, MSc Alexandre Dumontet Stephen P. Murphy, MD $299 or Less Julie A. Buckley, MD & Eric T. Fung, MD David Durany Lara Elsie Nguyen, MD Anonymous (3) Kenneth A. Buckwalter, MD Matthias Eberhard, MD Vu H. Nguyen, MD In memory of Michael D. Arsenault, Amy Bulger Per Eckerbom Jennifer L. Nicholas, MD DO, MA Matthew Burgess, MBChB Per Edlund Donald E. Nies, MD, PhD Ayat H. Abduljabbar Sandra Burghardt Jon Edwards Zdenka Fronek & Walter L. Olsen, MD Katy Acerra Matthew W. Burke, MD David J. Eisner, MD Dave C. Olson, MD Fern Adams, MBBCHIR Bruce E. Burton, MD Ramy El Jalbout, MD Mark C. Oswood, MD, PhD Seema Agrawalla, FRCR, MRCP Christian A. Cabrera, MD Thomas J. Eluvathingal, MD Carol & Mitchell T. Pace, DO Remi Ahfir Wenchao Cai, BMBS, PhD Masahiro Endo, MD Judy S. & C. Leon Partain, MD, PhD Djamel Ait Ali Yahia Rogerio Caldana, MD, PhD John Eng, MD Aalpen A. Patel, MD Nila J. Akhtar, MD Malcolm Campbell Joseph P. Erinjeri, MD, PhD Steven H. Peck, MD Jorge M. Alardi, MD Nancy J. & Robert E. Campbell, MD Janet & David R. Erwin, MD Yulan Peng, MD Marissa L. Albert, MD, MSc In memory of William G. Bradley Jr., William A. Fajman, MD Paul F. Pizzella, MD Daniel Alcorn, MBBS MD, PhD Kathy & Craig A. Fenton, MD Stuart W. Point, MD Suzanne & Daniel C. Alder, MD Rich Caponigro Antonio C. Fernandes Sr. Kristin Porter, MD, PhD Elizabeth & Joseph P. Alenghat, MD Lynn N. Carlton, MD Wilson R. Fernandes Jr., BDS Adnan A. Qalbani, MD Tobias Alich Anne & Thomas M. Carr III, MD Isabel Fernandez, MD Daniel J. Quenneville, MD Ghada M. Al-Makhaita, MBBS & Elena Casado Julio Fernandez Mata Oscar J. Ramirez, MD Mohammed Al-Abdulazin Hayde D. Rodriguez & Nicholas J. Ferris, MBBS Roy Ramsey Jr., MD Fernando A. Almeida, MD Omar Cazares Urbina, MD Lauri & Irwin M. Feuerstein, MD Michael Rechitsky, MD Ann V. Als, MD Carolina R. Chacon, MD Angela J. Feyerabend, MD Richard R. Reece, MD Waleed M. Althobaity, MD Alan D. Chan, MD Greg Filewood, MBBS Caroline A. Reich, MD, PhD Sergio A. Altube, MD Edward H. Chan, MSc, RT Kathleen R. Fink, MD Susan & Matthew D. Rifkin, MD Enrique Alvarado Burgos, MD Wing Pong Chan, MD Michele Morris, MD & Clinton Rogers, MD Esteban Amador Vargas, MD Ai-Lee Chang, MD Joel E. Fishman, MD, PhD Christopher J. Roth, MD Fernamda d. Amorim, MD Deborah J. Charles, MD James B. Fitzgerald, MD Claudia Rummeny, MD & Chansik An, MD Sumblina A. Chaudhary, MD Lindsay Fleming Ernst J. Rummeny, MD Mary Ancona, BSC David Chen, MD Richard A. Flom, MD Kazuhiro Saito, MD Marissa Anderson Grace Chen Robert Flores Karen L. Salzman, MD Kristen Andreopoulos Ji Chen, PhD, MENG Monica M. Forbes-Amrhein, MD, PhD Markus Schwaiger, MD Jeff Andreski Melissa M. Chen, MD Parham R. Fox, MD Jackie Chang & Ross E. Schwartzberg, MD Julie Angel Srilakshmi & Steven Fox In memory of Gary M. Glazer, MD Marcia Angulo S. Murthy Chennapragada, MBBS Kim & Nicholas Frankel, MD Nirav C. Shah, MD Daniela Angulo Salazar, MD Wui Kheong Chong, MD In honor of Dr. Shane McAlister Supriya Sharma, MD Bangalore Anil Kumar, MD, FRCR Denis L. Chossiere, MD Arlene & David B. Freiman, MD Navi Shergill, MD, FRCPC Howard J. Ansel, MD Cristina G. Ortega & Greg Friedel, MD Rajit S. Shetty, MD Domenico Antonio Donina Rodri Cesar Cisneros Victorino, MD Shinya Fujii, MD James H. Short, MD, PhD Noah B. Appel, MD Glenn S. Coats, MD, MBA Hirofumi Fukuchi, RT Shawn S. Shrawny, MD Maria de Fatima Aragao, MD, PhD Carol L. Collings, MD & Matthew G. Haney Irene & Richard E. Fulton, MD Judith Sidell Rick Arnold Cathy Condie Maria C. & Marcelo B. Funari, MD In memory of Michael S. Sidell, MD Elsa M. Arribas, MD Joseph Conner Shannon M. Gaffney, DO Julie & Spencer Sincleair, MD Adel A. Assaf, MD Andrew Conway Pilar Soleda Garcia Raya Zahida K. Sirdar, MBBCh, FRCR Brett L. Austin, MD Fernando Corredor Ishan Garg, MBBS Anne Stewart & Claude B. Sirlin, MD Juliana Azevedo, MD Joe Corrigan, MEng Suzanne & Richard A. Geise, PhD Kathleen & Gerald C. Smidebush, MD Sheereen L. Azimpoor, MD Arthur D. Cortez, MD Brad Genereaux Troy R. Smith Jr., MD Elizabeth & Algis V. Babusis, MD David L. Coy, MD, PhD Hilary & Anthony Gentile John A. Snyder, MD Karen J. Back, MD & Laura A. Coyle, ARRT, RT In memory of Edward & Moira Wilde Kurubarahalli R. Saroja, MD & Donald M. Bachman, MD Dave Cunningham Najoua & Hassen A. Gharbi, MD Kudavalli N. Somashekar, MD Silvia Badillo Rodriguez Portugal, MD Kathleen C. Curiel Richard Ghavami, MD Swithin J. Song, MBBS Jeanne W. Baer, MD Nancy S. Curry, MD & Robert Curry Maryellyn Gilfeather, MD Evangeline S. & Neil T. Specht, MD Adam Baiers Horacio R. D'Agostino, MD, FACR, FSIR Wesley Gilson, PhD Thomas W. Stohrer, MD Wayne J. Bailey, MBBCh Kasey & Michael E. Daniel, MD Spyridon Gkoumas Chockeo Syvanthong, MD Jonathan Baker Hallie & Denny J. Dartez, MD Virginia Goble Janet Tanus Hajj, MD & Philip A. Baker, MD Mariette Dautt Medina, MD Roberto Godoy Francisco Avelar, MD Alberto P. Bambirra, MD Gavin M. Davis, MBChB Audrey & Garry E. Gold, MD, MSEE Jean-Pierre Tasu, MD, PhD Yehiel Barki, MD Jennifer M. & Kirkland W. Davis, MD Paul Goldberg, MD Carol & Thomas R. Thompson, MD T.K. Barnard Paulo De Camargo Daniel W. Golden, MD Norman B. Thomson III, MD, MBA Brenda J. Barnes, MBBS Maarten De Cuypere Antonio Carlos P. Gomes, MD John M. Troupis, MBBS, FRANZCR Mario de La Portilla, MD Ana Maria Gomez, MD

18 RSNA News | March 2018 Mikhail Goncharov Kazuya Kawashima, MD Piotr J. Maniawski, MSc Julie & Ed K. Phillips, MD Alberto Gonzalez, MD Yasushi Kawata, MD Laurene C. Mann, MD & John Loughlin Marc J. Pinchouck, MD Srikumar Gopalan, MD Aoshima Kazuo Magda Marcon, MD Marvin Platt, MD Sallye R. Granberry, MD Aimee V. Keller, MS Fernando E. Mariz, MD Sergio Podgaec Richard I. Gray, MD Ian A. Kellman, MD Shoichet Martin, MD Bruno A. Policeni, MD Mark Greenberg, MD Kelly Kennell, MD Hector Martinez Beatriz d. Prado, MD Sofiya Greenberg, MD Shimasaki Kensuke Jaime Martinez, MD Christine A. Quinn, MD Antje L. Greenfield, MD & Wilhelm H. Kersjes, MD, MBA Manuel Martinez Pamela Quinn Steven M. Greenfield, MD Lauren Kerwin, MD Carolina Aponte, MD & In memory of Carol Lazaroff David C. Gregg, MD Matt Ketko Santiago Martinez-Jimenez, MD Denis Quittau, MD Robert J. Gresick Jr., MD Timothy Keys Judith & Kenneth W. Matasar, MD Liat Kishon-Rabin & Andrew M. Rabin, MD Rene Griffioen Surekha D. Khedekar, MD Mahan Mathur, MD Martin Rajchel Jeanne & Thomas M. Grist, MD Amar U. Kishan, MD Mifumi & Kiyoshi Matsueda, MD Rebecca Ramb Tim Grobe Kolleen Klein Erik J. Maurer, MD Vital Rangashamanna, MBBS Ilka M. Guerrero, MD In memory of Barbara Norris Sally H. May Thretha Reddy, MBBS, MD Jose David Guio Fernandez, MD Thomas E. Knight, MD Hilarie B. & Robert C. McKinstry III, MD, PhD Dave Reinhardt Mirela A. Gurgel, MD & Marcos Knobel Brian McNamee, MD Kim Rendon Fernando V. Gurgel, MD Jason Knox Michael J. Meagher, MD John M. Rennick, MD Marcelo d. Gusmao, MD Matthew Koch Dhruv Mehta, MS Arich R. Reynolds, MD, MPH Andre Hagen Julie Kraemer Edward Melian, MD Marcelo Ribeiro, MD, PhD Martin Hagenbeek Jean L. Kraft, MD Benjamin Mendez, MD Lisa A. Ribons, DO H. Phillip Hahn, MD Dan Kramer, MD Fernando Mendez Mark A. Richardson, MBBCh, FFRad(D)SA Munetaka Haida, MD, PhD Renee & Michael C. Kreeger, MD Arash Meshksar, MD Ilene & Yale Richmond, MD Astrid Hamann Robert Kricun, MD Mandie Miller Oralia C. Rico Rodriguez, MD, PhD Lynwood W. Hammers, DO Jean & Arthur F. Kriner, MD Thais Minett, PhD Matthieu L. Riffaud, MD Tommy Hansen Paola C. Kuenzer Goes, MD Trevor Mitchell Renato Ripamonti, MD Donald Hardie Louis Kuitenbrouwer Rogerio B. Molinari, MD E. Russell & Julia R. Ritenour Curtis L. Harlow, MD Stephen Kwak, DO Carla G. Monetti Jose Rivera Mary R. & Donald P. Harrington, MD Romain Labas Cuauhtemoc Monroy Glen Roberts Lawrence I. Harrison, MD David F. Lackner, MD Tonatiuh Monroy Keli Rodrigues Tom Hartley Miriam Ladin Frederick J. Monsour, MD Guillermo Rodriguez Jason B. Hartman, MD Pierre Laforge Raquel A. Moreno, MD Nancy & John O. Roehm Jr., MD David F. Hayes, MD Joe Lamotta Harold Moskowitz, MD David M. Roelke, MD Jeremy J. Heit, MD, PhD Gong-Yau Lan, MD Jeanette M. Moulthrop, MD & Natalia Rossel, MD Joan I. & Albert E. Hesker, MD Bina & Laxminarayana Lanka, MBBS Mark Moulthrop Andrea J. Rothe, MD & Michael Shevach Harriet W. & James C. Hewitt, MD Dave Lashmet Matthew Muetzel Tom Rowden Jennifer A. Hill, MD Stephanie Lau Tricia & Mark E. Mullins, MD, PhD Richard B. Ruchman, MD Lory Hines Christoff Lauff John P. Mulloy, MD Brian C. Ruiz de Luzuriaga, MD Akira Hiroshige Andrew L. Laurel, MD Marcia E. Murakami, MD Tim Ryan Kinson Ho Megan Lawler Satoshi Murakami Marwan H. Saab, MD Leo Hochhauser, MD Thomas J. Leach Rhiannon Myracle, MS Stephen W. Sabo, DO Lisa Hof Peter Leander, MD, PhD Helen R. Nadel, MD Caryl G. Salomon, MD & Daniel R. Moon Janet C. Hoffman-Tretin, MD Joseph Ledsam, MBChB Anne & Rory M. Nelson, MD Alvaro J. Sanchez, MD Jeffrey W. Hoffmeister, MD Emil J. Lee, MD Matthew H. Nett, MD Sumithra Sannasey, MBBS, MA Christine Holland Patricia E. Lee, MD Kim-Son Nguyen, MBBS Alexandra Sarran Eun Kyoung Hong, MD Bob Leigh Refky Nicola, MSc, DO Michael R. Savino, MD Kuhn Hong, MD Bernadette Leonard Wouter H. Nijhof, MSc Doris & Robert E. Schaefer, MD Arnold B. Honick, MD Georges B. LeRoux, MD Margarita Noriega Thomas Scheper Naomi F. Honjo, MD Louise Nolet & Jacques J. Levesque, MD Chuck Nortmann Richard S. Schilling Frank G. Hoogenraad, PhD Douglas S. Lewis, MD David M. Novick, MD James R. Schmidgall, MD Allison & Kent R. Hootman, MD Karl Lherisson, BA Victor Nudelman Thomas M. Schmidlin, MD Matthew Hoover, MBA Xin Li Raphael Nycz Shelley Adamo & Jon M. Hopkins, MD Yi Li, MD, MS Tamar K. & Alan E. Oestreich, MD Matthias H. Schmidt, MD, MSc Aurora & Isidro L. Huete, MD Gabriel V. Lima, MD Akio Ogura, PhD Paul Schoenhagen, MD Joshua A. Huff, MD Shih-Chieh Lin Shigeo Okuda, MD Keith G. Schroeder, MD Adam Huffman, MBA Thomas Lindstroem Allison L. Oldfield, MD Thomas Schroeder Donald H. Hulnick, MD Joseph P. Li Puma, MD Gerard Oleary Clemens Schulze-Briese Stephen Hulse, MD Harold I. Litt, MD, PhD David Olvera Sr., MD Fides Schwartz Ming-Fang Hung & Guo-Long Hung, MD Ron F. Loch Jr., MD Paul V. O'Moore, MD Eduardo Scortegagna Jr., MD Laura Hupert Michelle Lockett Anne G. Osborn, MD Fernando A. Segabinazzi, MD Phan T. Huynh, MD Christian Lofman Jamie Osmond Kimberly Seifert, MD Rubina & Muneeb S. Hydri, MBBS Richard J. Loges III, MD Orhan K. Oz, MD, PhD Morozov Sergey Ayumi Ihara William Lomas Laura & Orhan S. Ozkan, MD Michael E. Shahan, MD Zeenia Irani, MD, MS Ana P. Lourenco, MD & Myrna Veronica Palma Garzon, MD Kirill Shalyaev, PhD Paul Jackson Robert J. Tubbs, MD Chihliang Pan Neal Sharkey Christine Quinn Janicki, MD & Meghan G. Lubner, MD Sae Jin Park, MD Monda L. Shehata, MD Paul C. Janicki, MD Rachael Lugo Dimitri A. Parra, MD Peter Shen Edward A. Janon, MD Darren P. Lum, MD Dominique Pascal-Ortiz, MD, PhD Yun R. Sheu, MD, MS Jeremy Jeantroux, MD Raizza Luzzi Jay U. Patel, MD Rasu B. Shrestha, MD, MBA Camp Jenkins Patrick J. Lynch, MD Neil G. Patel, BS Manohar M. Shroff, MD Mona Johansson Paul C. Lyon, BMBS, DPhil Shodhan L. Patel, MD Elena & Jose Sierra, MD Michele Jones Jie Ma Maria C. Patricio, MD Claudia L. Silva, MD Ger Joosten Mary I. & Denton E. MacCarty, MD Judith Patterson, ARRT, RT Eliezer Silva Inger Lisbeth K. Josephson, MD In memory of Robert R. Duhamel, MD Trish & John A. Patti, MD Mauricio Silva Madalsa Joshi, MD Erika Machorro John M. Paulett, MS Yean P. Silva Hidalgo, MD William T. Joyce III, MD Clayton Macion Anabela G. Peres, MD Adam D. Singer, MD Linda O. Judge, MD Yannick Magliano Carment Perri Chris Skinner Souad Kabil Vasantha & Sophia B. Peterman, MD, MPH Kelly M. & Anthony J. Skiptunas III, DO Patricia Kaeding Mahadevappa Mahesh, MS, PhD Erik Peterson In honor of Dr. William Shields Jose Kairuz Saez Satkurunathan Maheshwaran, MD William Peterson Melissa Slater Andrew J. Kalnin, MD Anand Majmudar, MD Laura Petrich Derek Smit Rony Kampalath, MD Fatma H. Makame, MD, MMed Elena Petrusa Santos Gregory B. Smith, MD Thanat Kanthawang, MD Patrick C. Malloy, MD Roger T. Pezzuti, MD Deborah Hall & Ronald P. Smith, MD Iris T. Katen, MD Leena Mammen, MD Timothy M. Pfeifer Conrad Smits Satoshi Kawakami, MD Gaurav Manchanda Mark J. Pfleger, MD Continued on next page

March 2018 | RSNA News 19 NEWS YOU CAN USE

Continued from previous page

William H. Snyder Kurt T. Teichman, BSC Ignasi Vivas In honor of Sharon Skeen & the RSNA Dubrova Sofya Benoit Tejedor Ijtsuri Viveros Education Staff Rob Solgat Philip A. Templeton, MD Fabien Voix David Widmann Cristiane G. Spadoni, MD Masahiro Terashima, PhD Philipp L. von Knebel Doeberitz Christine Wiggins, PhD & Michael C. Spellman, MD Renate Tewaag, MD Satoshi Wakai Richard H. Wiggins III, MD Carolyn & Kenneth A. Spero, MD Ruedi F. Thoeni, MD Scott Walter, MS David Wilkins Tanop Srisuwan, MD Victoria Knoll & Richard B. Thropp, MD Arthur C. Waltman, MD Nancy Wilkins Summer & Scott D. Steenburg, MD Natalie Tishkowski Xue Wang, MD Peter Wilkop Andre Steinbuss Reina Tonegawa, MD, PharmD Yi-Fen Wang, MD Robert G. Wilson, MD Bruce G. Stewart, MD Martin Tornquist-Fauster, MD Denise M. Warner, MBBS & Bruce Allen Adam B. Winick, MD J. Martin Stewart, MD Jeff Trail David Wasserman, MD Nelson Wolosker Mark Stoffels Roberta Trevisan, MD & Monr Trevisan Ann & Neil F. Wasserman, MD Jade J. Wong-You-Cheong, MD Rudi Stokmans, MD Igor Trilisky, MD Kota Watanabe, MD Mark Woods Christopher M. Straus, MD Bradley R. Trotter, MD John M. Watkins, MD Maosheng Xu, MD Floris Sturkenboom Mattias Truchot James H. Watt, MD Milad Yazdani, MD Thiru A. Sudarshan, DMRD, FRCR Louise M. Truong, MD John A. Watts V, MD, MS Mandy Yip Pamela K. Sung, MD Yuichiro Tsuchiya, PhD, MBA Natalia Weber, MD John Y. Young, MD Joseph B. Sutcliffe III, MD Kyo Tsuda, MD XuanMeng Wei Dirk Zachow, MD Roger Svensson Kazuhiko Ueda, MD Alex J. Weiss, MD Ricardo F. Zagatti, MD Timothy J. Sweeney, MD Takayoshi Uematsu, MD, PhD Karen J. Weiss, MD Christian A. Zamora, MD Timothy P. Szczykutowicz, PhD Almir A. Urbanetz, MD Alfred F. Weitzman, MD Juan M. Zapani Leizle E. Talangbayan, MD & Katarina Van der Hoeven Abby Weldon Jerahmie L. Zelovitzky, MD Glenn Gabisan Lorinda & Nicolas T. Van Der Walt, MBChB Lewis Wexler, MD Ting Ting Zhang, MA, MBBS Ryuichiro Tani Gert Van Gompel, PhD Donald B. Wheeler Jr., MD Yuqiao Zheng Michael Taricani, RT Marius Van Meel Benjamin D. White, MBBS, FRANZCR Harry L. Zinn, MD Eloisa T. Martínez & Reija E. Vastrik, MD Karley White Eduardo Zlotnik Manuel Salvador Tarrason, MD, PhD Jan Vermeulen Mark E. Whitley, MD Katherine A. Zukotynski, MD Karen M. & Robert D. Tarver, MD Hugo Vidal, MD Mary Ellen Wickum, MS Hiroyuki Tatekawa, MD Manjupriya & Raghu Vikram, MBBS In honor of Betsy Lockett & the RSNA Membership Staff

Journal Highlights The following are highlights from the current issues of RSNA’s two peer-reviewed journals.

Quantitative Elastography Methods in Liver Disease: Current Evidence and Future Directions

Because treatment strategies and prognosis differ greatly depending on the severity of liver fibrosis, determining fibrosis staging is important. Liver biopsy is the method of choice for fibrosis evaluation, but alter- native, noninvasive methods of evaluating liver health are being developed, such as ultrasonographically (US) and MR-based elastography. In an article published online in Radiology (RSNA.org/Radiology), Paul Kennedy, PhD, Icahn School of Medicine at Mount Sinai, New York City, and colleagues review the techniques, results and limita- Images in a 59-year-old man with chronic hepatitis C virus infection and infiltrative HCC in right tions of US- and MRI-based elastography hepatic lobe (arrows). MR elastography demonstrates increased stiffness (7.7 kPa) compared with techniques. background liver parenchyma (3.2 kPa). Another HCC nodule is present in left lateral hepatic lobe (arrowheads), also demonstrating increased stiffness. HCC = hepatocellular carcinoma. Quantitative US elastography methods Radiology 2018;286(3):737-763) © RSNA 2018. All rights reserved. Printed with permission. include transient elastography (TE) – the most validated elastographic technique – and acoustic radiation force impulse stiffness measurement can be into account potential con- (ARFI) techniques. MR elastography affected by a variety of factors founding factors of liver offers equivalent to slightly better diagnos- such as hepatic inflammation, stiffness measurements, pitfalls tic accuracy than TE and ARFI, although congestion and cholestasis while TE can and technical limitations. it is less well validated and less available be affected by steatosis. "The emergence of advanced tech- than US elastography methods. Ultrasound and MR elastography niques such as three-dimensional MR Increasing fibrosis stage is associated techniques have developed into accurate elastography and US-based controlled with increased liver stiffness, providing methods for quantitative, noninvasive attenuation parameter measurement may a discriminatory feature that can be diagnosis of liver fibrosis in a wide range increase the accuracy of fibrosis and ste- exploited by elastographic methods. How- of etiologies, the authors concluded. atosis staging in liver disease, although ever, for all elastographic methods, liver “Interpretation of results should take more data are needed," the authors write.

This article meets the criteria for AMA PRA Category 1 Credit™. SA-CME is available online only. 20 RSNA News | March 2018 High-Intensity Focused Ultrasound for Pain Management in Patients with Cancer Cancer-related pain affects up to 80 Currently, MRI- percent of patients with malignancies. guided HIFU is High-intensity focused ultrasound recommended as a (HIFU) is a noninvasive technique that second-line treatment can be used to achieve pain palliation by after unsuccessful producing several effects, including tissue radiation therapy for denervation, tumor mass reduction and palliation of pain neuromodulation, each of which can related to nonspinal influence different pathways at the origin and nonskull bone of the pain. metastases. Current In the March-April issue of RadioGraphics evidence suggests (RSNA.org/RadioGraphics), Susan Dababou, that the use of HIFU MD, Sapienza University of Rome, Italy, can facilitate reduced Treatment of bone metastasis in the right scapula, and colleagues discuss the emerging tech- pain in patients with secondary to melanoma, in a 74-year-old man. nique involving the use of high-energy pancreatic adenocarcinoma, with up to (a, b) Axial dynamic contrast-enhanced color-coded ultrasound waves to precisely ablate a 81 percent of affected patients reportedly T1-weighted MR images acquired before (a) and after well-circumscribed target volume with experiencing pain relief. (b) HIFU treatment show intense vascularization of the malignant area (arrows in a) before treatment and MRI or ultrasonographic “The improvement in pain markedly decreased vascularization (* in b) after the (US) guidance, without control can be immediate, and procedure. Color gradients indicate blood perfusion, damaging the surrounding the procedure can be safely from less perfused (blue) to highly perfused (red). healthy structures. combined with chemotherapy and radi- (RadioGraphics 2018:38;2;InPress) © RSNA 2018. All rights The main benefit of HIFU for cancer ation therapy to synergistically enhance reserved. Printed with permission. patients is the capability to address their effects. Moreover, this procedure is different features of a malignancy by noninvasive, and the absence of ionizing necessary after the recurrence of decreasing painful stimuli, locally con- radiation ensures that there is no radia- symptoms or worsening of the primary trolling the tumor, potentially enhancing tion-related risk if retreatment is deemed condition,” the authors write. local drug delivery and stimulating the host antineoplastic immune response. This article meets the criteria for AMA PRA Category 1 Credit™. SA-CME is available online only.

Listen to Radiology Editor David A. Bluemke, MD, PhD, discuss this month’s research you need to know about. Podcasts summarize the importance and context of selected recent articles. Subscribe today at RSNA.org/Radiology-Podcasts and never miss a single episode.

Articles are: “MR Spectroscopy–derived Proton Density Fat Fraction Is Superior to Controlled Attenuation Parameter for Detecting and Grading Hepatic Steatosis” Jurgen Henk Runge, MD, PhD, and colleagues. “Evaluation of Kidney Stones with Reduced–Radiation Dose CT: Progress from 2011−2012 to 2015−2016—Not There Yet” Karrin Weisenthal, BA, and colleagues. “Temporary Hearing Threshold Shift in Healthy Volunteers with Hearing Protection Caused by Acoustic Noise Exposure during 3-T Multisequence MR Neuroimaging” Chao Jin, PhD, and colleagues.

Listen to RadioGraphics Editor Jeffrey S. Klein, MD, and authors discuss the following articles from recent issues of RadioGraphics at RSNA.org/RG-Podcasts

“MR Imaging of Muscle Trauma: Anatomy, Biomechanics, Pathophysiology, and Imaging Appearance,” Dyan V. Flores, MD, and colleagues. “Prostate-specific Membrane Antigen PET: Clinical Utility in Prostate Cancer, Normal Patterns, Pearls, and Pitfalls,” Michael S. Hofman, MBBS, and colleagues. “Acute Radiologic Manifestations of America’s Opioid Epidemic,” David D.B. Bates, MD, and colleagues.

March 2018 | RSNA News 21 NEWS YOU CAN USE

Radiology in Public Focus Radiology in Public Focus Media Coverage of RSNA RSNA Updates Gadolinium Position Statement In November 2017, more than 20,500 RSNA-related news stories The FDA recently issued a safety announcement requir- were tracked in the media. These ing a new class warning and other safety measures for stories reached an estimated audience all gadolinium-based contrast agents (GBCAs) used for reach of 10.6 billion people. MRI. These include requiring a new patient Medication Coverage included U.S. News & Guide and a requirement for manufacturers of GBCAs to World Report, Newsweek, The Boston conduct human and animal studies to further assess the Globe, Daily Mail, San Francisco safety of these contrast agents. RSNA updated its posi- Chronicle, Houston Chronicle, BBC. tion statement on gadolinium-based MR contrast agents com, Forbes.com, Reuters.com, to reflect this news. No other changes were made to the WebMD, Drugs.com, HealthDay, position statement. Philly.com, The Arizona Republic, Access the updated RSNA position statement at Yahoo! Finance, Pittsburgh Post- RSNA.org/Position-Statements and the updated FDA state- Gazette, Milwaukee Journal Sentinel, ment at fda.gov. CBSNews.com, Health.com, Diagnostic Imaging and Auntminnie.com.

March Public Information Outreach Focused on Colorectal Cancer In recognition of National Colorectal Cancer Awareness Month in March, RSNA is distributing radio public service announcements (PSAs) encouraging listeners to get screened for colorectal cancer.

New on RadiologyInfo.org Wants to RadiologyInfo.org Share Your Patients’ Stories March is Colorectal Cancer Awareness Month. RadiologyInfo.org – the RSNA-ACR patient information website – Do your patients know they should begin helps patients better understand radiology and the role radiologists screening for colorectal cancer at age 50? play in their healthcare. Now, RadiologyInfo.org is exploring a Encourage them to visit RadiologyInfo.org’s new way to spotlight radiology with the public by sharing patient Colorectal Cancer Screening page to learn stories — your patients’ stories. more about this disease, its risks, symptoms Do you have patients who would be willing to share their radio- and available screening methods such as CT logic care experience with others? Email [email protected] colonography. with the subject line “Patient Stories” to connect us with your patients. Visit the RadiologyInfo.org Patient Stories section to learn more about this opportunity.

22 RSNA News | March 2018 Value of Membership RSNA Offers Affordable Membership as Residents Transition into Practice

There are numerous things that can be challenging about transitioning to full-time practice. Maintaining your RSNA membership should not be one of them. Residents and fellows transitioning from training receive reduced RSNA membership rates during their first and second years of practice – just $100 in year one and $200 in year two. This RSNA benefit gives transitioning members time to settle into the profession before paying the full membership fee in year three. Under the program, transitioning members receive all the benefits of full membership, including subscriptions to Radiology, RadioGraphics and RSNA News, free standard admission (with advance registration) to the RSNA annual meeting and free access to hundreds of online CME opportunities. For more information, contact [email protected] or 1-877-RSNA-MEM (1-877-776-2636) or 1-630-571-7873 outside the U.S. and Canada.

Education and Funding Opportunities RSNA/ASNR Comparative RSNA 2018 International Effectiveness Research Travel Stipend Program

Application Deadline The RSNA International Travel Training (CERT) Program April 30 Stipend Program aids eligible members from developing or Application Deadline Apply now for the RSNA/American low-resource nations by partially April 30 Society of Neuroradiology (ASNR) defraying travel expenses related to attending the RSNA Comparative Effectiveness Research annual meeting. For more information and to apply, visit Training (CERT) Program. There is RSNA.org/Annual-Meeting-International-Travel-Stipend. no fee for this course. Apply at RSNA.org/CERT or contact RSNA staff at [email protected] with questions.

Updated Ethics and Professionalism Courses Now Available

The RSNA Professionalism Committee The series includes such topics as “Physi- credits for the Ethics and Professionalism recently reviewed and updated the Ethics cian-Physician and Physician-Patient Inter- Online Courses range from 1.50 to 3.0 and Professionalism courses on the RSNA actions,” “Personal Behavior, Peer Review AMA PRA Category 1 Credits™ per course. Online Learning Center. This 11-course and Contract Negotiations with Employers” These credits and can be applied toward series is essential to the practice of diag- and “Conflicts of Interest.” the American Board of Radiology (ABR) nostic radiology, radiation oncology and Each self-guided course includes a CME MOC self-assessment requirement. medical physics. test to help learners assess their compre- RSNA members can access these courses Developed in 2011, updated in 2014 hension and application of the principles for free in the Online Learning Center at and again in 2017, the online courses and practices described in the course. Education.RSNA.org. Enter “Ethics and educate radiologists on how to navigate RSNA members can earn SA-CME Professionalism” in the Search field. tricky ethical situations that can arise in credits for the successful completion (80 the workplace or during academic research. percent or better score) of the tests. Course

March 2018 | RSNA News 23 NEWSSECTION YOU CAN USE

Annual Meeting Watch RSNA 2018 Online Abstract Submission Now Open

The online system to submit abstracts for RSNA 2018 is open. The submission deadline is noon Central Time (CT) on Wednesday, April 11, 2018. Abstracts are required for scientific presentations, education exhibits, applied science, quality improvement reports and quantitative imaging reading room showcases. To submit an abstract online, go to RSNA.org/Abstracts. The easy-to-use online system helps the Scientific Program Committee and Education Exhibits Committee evaluate submissions efficiently. For more information about abstract submissions, contact the RSNA Program Services Department at 1-877-776- 2227 within the U.S., or 1-630-590-7774 outside the U.S. The top neuroradiology scientific paper as selected by the Scientific Program Committee will receive a $3,000 award at RSNA 2018. Students, clinical trainees and post-doctoral trainees are eligible to receive $500 travel awards for top-rated abstracts accepted for presentation at RSNA 2018. Trainees are also eligible to receive a $1,000 research prize. Full eligibility requirements for all awards are available with the 2018 Call for Abstracts.

Present at RSNA 2018: u Scientific Presentations u Applied Science November 25-30 u Education Exhibits 104th Scientific Assembly & Annual Meeting u Quality Improvement Reports u Quantitative Imaging Reading Room Reserve your RSNA 2018 Hotel Now! Hotel reservations with discounted rates for all RSNA 2018 attendees are available at RSNA.org/Annual-Meeting.

24 RSNA News | March 2018 Technology Forum

2018 IHE® Connectathon Draws Leading HIT Vendors

Top health information technology (HIT) vendors gathered in Cleveland in January for the 20th annual Integrating the Healthcare Enterprise (IHE®) North American Connectathon. More than 63 organizations and nearly 500 individuals participated in the live, cross-vendor, supervised and structured event where industry leaders tested the implementations of IHE profiles to advance health IT interoperability. More than 100 IHE Profiles were tested this year. An event within the Connectathon is the Plug-a-thon, which offered four tracks to help participants explore and create new capabilities for products that interoperate with each other, especially older, legacy systems used in hospitals. These included sessions on FHIR®, Blockchain and its uses in healthcare, mHealth and the growing number of medical equipment, facility and resource management solutions promoting sensory information. RSNA and the Health Information and Management System Society (HIMSS®) have sponsored the Connectathon since its inception in 1999. For more information, visit RSNA.org/IHE.aspx or IHEUSA.org/ what-is-ihe-connectathon.

Industry leaders gathered recently for the IHE® Connectathon to test IHE profiles and advance IT interoperability.

COMING Next month, RSNA News will report on the challenges radiology faces in serving NEXT rural areas of the U.S. MONTH

March 2018 | RSNA News 25 GET NOTICED

Present at RSNA 2018: u Scientific Presentations u Applied Science u Education Exhibits u Quality Storyboards u Quantitative Imaging Reading Room

EARN RECOGNITION!

The RSNA Travel Award Program for Students Up to 430 top-rated abstracts from current RSNA members will earn a $500 travel stipend. Kuo York Chynn Neuroradiology Research Award The top scientific paper as selected by the Scientific Program Committee will earn a $3,000 award recognition.

Visit RSNA.org/Abstracts for complete guidelines.

Submit online beginning January 2018 at RSNA.org/Abstracts through Wednesday, April 11, 2018, 12 NOON Chicago Time.

Questions? Call 1-877-776-2227 (within U.S.) or 1-630-590-7774 (outside U.S.) Includes courses in joint sponsorship with the American Association of Physicists in Medicine

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