DOCSLIB.ORG

Volume 61, Number 4, December 1990 Published Quarterly for The

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Volume 61, Number 4, December 1990 Published Quarterly for The Volume 61, Number 4, December 1990 LEPROSY REVIEW Published Quarterly for the British Leprosy Relief Association ISSN 0305-7518 Leprosy Review A journal contributing to the better understanding of leprosy and its control British Leprosy Relief Association LEPRA Editorial Board PRO~ESSOR J . L. TURK (Chairman and Edilor) DR R . J . W . R EES , C.M .G . (Vice-Chairman) The Royal Coll ege of Surgeons National Institute fo r Medical Research Department of Pa thology, The Ridgeway 35- 43 Lincoln's Inn Field Mill Hill, London NW7 IAA London W C2A 3PN JANE EVILLE, M .B.E. DR M . J . COLSTON 5 Sandall Close National Institute for Medical Research Ealin g The Ridgeway, Mill Hill Lo ndo n W 5 IJ E London NW7 I AA PROFESSOR P. E. M . FINE DR PATRI CIA ROSE Department of Epidemiology Allendale Ho use and Populati on Sciences A ll endale Road London School of H ygiene Hexha m N E46 2DE and Tropical Medicine Keppel Street DR M . F. R . WATERS , O .B. E. London W C I E 7HT Hospital fo r Tro pical Diseases DR S. LUCAS 4 St Pa ncras W ay School of Medicine Lo ndo n NW l OPE University Col1ege and Middlesex Medical School, London DR H . W . WH EATE , O .B.E. U ni versi ty Street 50 Avenue Road, Belmo nt, Sulto n Lo ndo n W C IE 6JJ Surrey SM2 6JB Editorial Office: Lepra, Fa irfax House, Causton Road, Colchester C01 1 PU , England Assistant Editor: Jennet Batten, 94 Church Road, Wheatley, Oxon OX9 1 LZ, England Leprosy Review is published by the British Leprosy Relief Association (LEPRA) with the main objective of contributing towards the better understanding of leprosy a nd its control. Original papers o n al1 aspects of leprosy, including research, a re welcomed. In addition, Leprosy Review seeks to publish info rmation of educational value which is of direct benefit to the contro l of leprosy under field conditio ns, a nd hence to the individual patient. The J o urnal aims to interpret what is being done in other disciplines, particularly for field workers. From time to time the Editorial Board invites specia l articles or edito ri als from experts in various parts of the world, and gives considera ti o n to the production of a supplement or special number devoted to a particula r subject or theme of major impo rta nce. British Leprosy Relief Association Registered Offices: Fa irfax House, Causton Road, Colchester C01 7PU < • CONTENTS Editorial 3 13 Recent advances in the chemotherapy of leprosy. B. JI a nd J-H . G ROSSET : . Original Articles 330 Relationships between PGL-I antigen in serum, tissue and viahility of Mycobacterium /eprae as determined by mouse footpad assay in multibacillary patients during short-term clinical trial. SUZ ANNE C HA NTE A • J-L. C AR TEL, EVEL YNE PERA NI, L. N ' DELI , J . Roux a nd J-H . GROSSET 341 Anti-phenolic glycolipid I IgM antibodies in leprosy patients and in their household contact.s. G . SULC' EIl E and M. NAK UC' I 347 Positive Mitsuda lepromin reactions in long-term treated lepromatous leprosy. M . F. R. WATERS. D . S. RIDLEY a nd S. B. LUC'AS 353 Tuberculoid relapse in lepromatous leprosy. M . F . R. WA TE RS a nd D . S. RIDLEY 366 Disabilities in leprosy patients ascertained in a total population survey in Karonga District, Northern Malawi. ITA M . PO NN IGHA US , G . BOERRI GTE R, P. E. M. FI NE, J . M . PON NIGHA US a nd J UDITH R USSELL 375 Preliminary observations on myiasis in leprosy patients. SR EE VATSA. G . N . MALAVIYA , S. H USA IN, A . GIRDHAR , H . R. BHAT and B. K . GIRDHAR 379 Leprosy in Saudi Arabia, 1986-89. M . A . IflRAHIM , M . N. KORDY, A . H . AIDEROUS and A . BAH NASSY Special Article 386 Basic requirements for implementation of multidrug therapy- ILE P MEDICAL BU LLETI N Letters to the Editor 39 1 Multidrug therapy in paucibacillary leprosy. W . H . JOPLI NG 39 1 Are dapsone hypersensitivity reactions dose related? R. DE SOLD EN HOFF 392 Implementation of multidrug therapy for leprosy control programmes. D . PORICHHA 393 Comment: Assessment of histological response to treatment. I. A . C REE 394 Experiences with repeated quality controls of skin smears in different routine services in leprosy control programmes. LYSAMMA VETTO M a nd SUSANNE PRIT ZE 396 Acid-fast and H & E stainingscan be combined beller than in theTRIFF method. T. L. MIK O and S. B. L UC' AS 398 Amyloidosis- a possible minor factor contributing to the disappearance of leprosy from Northern Europe. A . H. PA TKI 399 Effect of calendula on trophic ulcers. S. KARTIK EYAN , R . M . C HAT URVEDI and S. V. NARKAR 400 Malignancy in plantar ulcers in leprosy. R. G . RI EDE L a nd SIPRA ADHIKARI 402 Pachydermoperiostosis and leprosy. W . H . JOPLI NG 404 Prevention of peripheral nerve damage in leprosy. J . H . RI CHARD US Teaching Materials and Services 405 Ne uropathic root in leprosy, Poona , India- best film awa rd Eye health at village level. The Interna ti o nal Huma n Suffering Index INFOLEP: Leprosy In ro rmatio n Services Arrican Leprosy Aid TDR: Tropical diseases o n the increase TDR: Ca ll ror applications ror suppo rt o r resea rch tra ining ( 1991 ) Water, Engineering a nd Development Centre, Loughborough, UK Leprosy poster rro m ALM Interna ti o na l a nd Wellco me WHO publicatio ns 1986- 1990 Action Health 2000, Cambridge, UK Tuberculosis skill book , M a rie Adelaide Centre, Karachi, Pakistan TALM ILEP-Cata logue o r teaching and learning materia ls Colour transpa rency teaching sets ro r India Steam steriliza ti o n 'slide set' Clinical guidelines: diagnostic and treatment manua l Making low-cost spectacles Leprosy; a guide ro r pro ressio nal wo rkers; TLM, South Arrica C hemotherapy or leprosy ro r control progra mmes. Video Leprosy- the misunder- stood disease. Film Tra nsmissio n o r HIV in health-care settings Health Technology Directions; immunisatio n Community Health Suppo rt Services (CHESS) Appropriate Health Resources and Techno logies Acti on Group (Colltellls continue all inside back cover) (Col1/el1/.l· conlinuedForn back cover) News and Notes 414 A model system for drug supply Care of patients with chronic renal failure in the Third World- lnternational Workshop • Moniaya Tuberculosis and Leprosy Control Services Report, 1989, Nlgena Drug labelling study • Leprosy in the People's Republic of China • WHO Liasion-Newsletter of the WHO Library and Health Literature Services Thinking about computers? • Glucose-6-phosphate dehydrogenase deficiency, sulphonamides and sulphones Acworth Leprosy Hospital Research Society, 20th Anniversary • The unquiel eye; a diagnostic gUlde N. D. Dlwan Memorial Award Fund Bombay Leprosy Project, Repor! 1976-89, Handbook of Leprosy, on sale in lndia BCG vaccination in leprosy; final results from Papua New Gumea Leprosy profiles, Sasakawa Memorial Health Foundation, Japan Erratum Wellesley Bailey Scholarship • Lepros Third World edition • Medication monitoring SocIal research methods for lhe study of tropical diseases (leprosy), Workshop Report, Hyderabad, lndla Essays on lepro�y Bureau for Overseas MedicaI Service (BOMS) 419 Index * * * Leprosy Review is published quarterly (Mar., June, Sept., Dec.) by the British Leprosy Relief Association (LEPRA). 1991: Volume 62, 4 issues; no, or f6.50 per copy, inclusive of postage and packing (UK and abroad). Subscription orders or enquiries should be sent to (LEPRA), Fairfax House, Causton Road, Colchester CO I I PU, England. At its own discretion, LEPRA will continue, and also expand, its policy of sending free issues of this journal to people in various parts of the world; this will include doctors working directly with leprosy who cannot alford the above subscription, or obtain foreign currency, together with selected Iibraries covering tropical medicine. © 1990 British Leprosy Relief Association. The appearance of the code at the bottom of the first page of a paper in this journal indicates the copyright owner's consent that copies of the paper may be made for personal or internaI use, or for the personal or internaI use of specific clients in the U .S.A. This consent is given on the condition, within the U.S.A., that the copier pay the stated per­ copy fee through the Copyright Clearance Centre, Inc., I Park Avenue, New York, N.Y. 10016, for copying beyond that permitted by Sections 107 or 108 of the U.S. Copyright Law. This consent does not extend to other kinds of copying, such as copying for general distribution, for advertising or promotional purposes, for creating new collective works, for resale or for copying or distributing copies outside the U.S.A. Printed in Great Brilain aI lhe Alden Press, Oxford Lepr Rev (1990) 61, 313-329 Editorial RECENT ADVANCES IN THE CHEMOTHERAPY OF LEPROSY The classical strategy of leprosy control, based on early detection and effective chemotherapy, is likely to remain unchanged for many years.I•2 Effective chemotherapy will still be necessary for the treatment of millions of leprosy patients even after a leprosy vaccine with proved effectiveness becomes available. The most important progress made in the history of leprosy control was the development and implementation of multidrug therapy (MDT) for both paucibacillary* (PB) and multibacillary* (M B) leprosy. Due to MDT, new hopes of controlling leprosy as a major public health problem have been raised. Around the topic of MDT we are trying to review the recent advances in the chemotherapy of leprosy. Basic concept of multidrug therapy By the end of the 1970s it was clear that attempts to control leprosy by life-long dapsone monotherapy were failing, because of the rapid increase of dapsone-resistance.
Load more

Recommended publications
  • MNEMONICS for Sure Success in PG Medical Entrance Examinations
    Mnemonics for Sure Success in MNEMONICS for Sure Success in PG Medical Entrance Examinations Second Edition Presents 600 high quality mnemonics Enhances quick recall and recollection of high value facts Provides “cutting-edge” technique in remembering “long-winding” statements/particulars/facts Packs mnemonics that count Presents 600 high quality mnemonics Enhances quick recall and recollection of high value facts Provides “cutting-edge” technique in remembering “long-winding” statements/particulars/facts Packs mnemonics that count MNEMONICS for Sure Success in PG Medical Entrance Examinations Second Edition Arun Kumar MBBS DNB(s) CBS Publishers & Distributors Pvt Ltd New Delhi • Bengaluru • Chennai • Kochi • Kolkata • Mumbai Hyderabad • Nagpur • Patna • Pune • Vijayawada Disclaimer Science and technology are constantly changing fields. New research and experience broaden the scope of information and knowledge. The author has tried his best in giving information available to him while preparing the material for this book. Although, all efforts have been made to ensure optimum accuracy of the material, yet it is quite possible that some errors might have been left. The publisher, the printer and the author will not be held responsible for any inadvertent errors or inaccuracies. MNEMONICS for Sure Success in PG Medical Entrance Examinations ISBN: 978-93-85915-33-8 Copyright © Author and Publisher First Edition: 2015 Second Edition: 2016 All rights reserved. No part of this book may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system without permission, in writing, from the author and the publisher. Published by Satish Kumar Jain and produced by Varun Jain for CBS Publishers & Distributors Pvt Ltd 4819/XI Prahlad Street, 24 Ansari Road, Daryaganj, New Delhi 110 002, India.
    [Show full text]
  • A Village Struggles for Eye Health
    Hanyane : A Village Struggles for Eye Health Hanyane - A Village Struggles for Eye Health This book deals with primary eye care in the context of community health and development and provides a practical guide to the diagnosis and management of common eye problems. It is written for health workers involved in providing primary and secondary eye care and will also be of relevance to all those striving to improve the health of people in rural communities. It has many illustrations which enable the story of Hanyane to be retold to community groups as an example of what can be achieved. The book has been produced by the International Centre for Eye Health, London, and is based on the varied experience of the three authors during their years in Africa. ERIKA SUTTER is an ophthalmologist from Switzerland who was in charge of eye services and training of ophthalmic nurses at Elim hospital in South Africa for over twenty years. Nine years were spent establishing the Elim Care Group Project on which the story and discussion about Hanyane is based. She now lectures on community eye health at the Swiss Tropical Institute, Basle, and the International Centre for Eye Health, London. ALLEN FOSTER works for Christoffel Blindenmission as Medical Consultant for Africa and is also a senior lecturer in preventive ophthalmology at the Institute of Ophthalmology in London. He spent nine years as Medical Superintendent at Mvumi Hospital in Tanzania where he developed a training programme for eye workers from East and West Africa. VICTORIA FRANCIS is an artist and health education trainer.
    [Show full text]
  • Reprinted Article
    REPRINTED ARTICLE Articles published elsewhere which are considered by the Edit01"ial Board to be of special interest a1"e, with permission r eprinted in i'tlll, or in condensed fonn, or in free translation. THF~ LUerO FORM OF DTFFl R]jj LEPRORY CAR I ~ IN A LOU1S1ANA NljjGRO 1 VINCF:NT J. ]}lmBES, :M.D., MON ROE RAMUELS, 1\ 1.])., OLLm P. V\TILLIAMS, M.D. AND J OHN J. 'W ALSH, 1\f.D.2 New 01'leans, Louisiana J.t was in 1852 that Lucio and Alvarado descrihed a form of leprosy as "Lepra manchada 6 lazarina" which had been observed by them at the San Lazaro Hospital in Mexico City. Although their description was excellent, this form of the disease was essentially forgotten until it was r estudied by Prof. Fernando LatapL Tn addition to circumscrihed. erythematous spots ("manchas "), chiefl y on the extremities, which went on to vesiculation, superfi cial necrosis and scarring, other salient features were summarized by Lucio and Alvarado (p. 10) as follows : " rn general, the loss of the eyebrows is of such valu€ for diagnosis, that united with the diminution of sensitivity and the disease of the nasal mucosa which we will mention later, without there being any other alteration, one may be sure that an individual is attacked by the disease of San Lazaro, and that this will very probably manifest itself in the spotted (' l\fanchada ') form." Lucio also str essed the poor prognosis. rn a series of papers Latapi and other Mexican c1 ermatologists ela borated further details.
    [Show full text]
  • Table I. Genodermatoses with Known Gene Defects 92 Pulkkinen
    92 Pulkkinen, Ringpfeil, and Uitto JAM ACAD DERMATOL JULY 2002 Table I. Genodermatoses with known gene defects Reference Disease Mutated gene* Affected protein/function No.† Epidermal fragility disorders DEB COL7A1 Type VII collagen 6 Junctional EB LAMA3, LAMB3, ␣3, ␤3, and ␥2 chains of laminin 5, 6 LAMC2, COL17A1 type XVII collagen EB with pyloric atresia ITGA6, ITGB4 ␣6␤4 Integrin 6 EB with muscular dystrophy PLEC1 Plectin 6 EB simplex KRT5, KRT14 Keratins 5 and 14 46 Ectodermal dysplasia with skin fragility PKP1 Plakophilin 1 47 Hailey-Hailey disease ATP2C1 ATP-dependent calcium transporter 13 Keratinization disorders Epidermolytic hyperkeratosis KRT1, KRT10 Keratins 1 and 10 46 Ichthyosis hystrix KRT1 Keratin 1 48 Epidermolytic PPK KRT9 Keratin 9 46 Nonepidermolytic PPK KRT1, KRT16 Keratins 1 and 16 46 Ichthyosis bullosa of Siemens KRT2e Keratin 2e 46 Pachyonychia congenita, types 1 and 2 KRT6a, KRT6b, KRT16, Keratins 6a, 6b, 16, and 17 46 KRT17 White sponge naevus KRT4, KRT13 Keratins 4 and 13 46 X-linked recessive ichthyosis STS Steroid sulfatase 49 Lamellar ichthyosis TGM1 Transglutaminase 1 50 Mutilating keratoderma with ichthyosis LOR Loricrin 10 Vohwinkel’s syndrome GJB2 Connexin 26 12 PPK with deafness GJB2 Connexin 26 12 Erythrokeratodermia variabilis GJB3, GJB4 Connexins 31 and 30.3 12 Darier disease ATP2A2 ATP-dependent calcium 14 transporter Striate PPK DSP, DSG1 Desmoplakin, desmoglein 1 51, 52 Conradi-Hu¨nermann-Happle syndrome EBP Delta 8-delta 7 sterol isomerase 53 (emopamil binding protein) Mal de Meleda ARS SLURP-1
    [Show full text]
  • Leprosy Review
    LEPROSY REVIEW The Quarterly Publication of THE BRITISH LEPROSY RELIEF ASSOCIATION VOL. XXIX. No. 4 OCTOBER 1958 Principal Contents Editorial A Modification of the Lepromin Te st Lepromin-like Activity of Normal Skin Tissue Leprosy and Lung Lesions A Trial of Antigen Marianum in the Treatment of Lepromatous Leprosy The Innervation of the Hand in Relation to Leprosy The Leprosy Endemic in Northern Rhodesia Clinicai Observations on Erythema Nodosum Leprosum Abstracts Reports Reviews 8 PORTMAN STREET, LONDON, W.l Price: Three Shillings and Sixpence, plus postage Annual Subscription: Fifteen Shillings, including postage LEPROSY REVIEW VOL. XXIX No.4. OCTOBER 1958 CONTENTS PAGE Editorial : Advances in the Lepromin Test ... 183 VII International Congress of Leprology 183 A Modification of the Lepromin Test J. A. KINNEAR BROWN 184 Lepromin-like Activity of Normal Skin Tissue T. F. DAVEY and S. E. DREWETT 197 Leprosy and Lung Lesions B. B. GOKHALE, U. OAK and S. M. WABLE 204 A Trial of Antigen Marianum as an Adjunct of DDS in the Treatment of Lepromatous Leprosy D. W. BECKETT 209 The Innervation of the Hand in Relation to Leprosy E. W. PRICE 215 The Leprosy Endemic in Northern Rhodesia with Special Reference to Sex Incidence J. T. WORSFOLD 222 Clinical Observations on Erythema Nodosum Leprosum I. A. SUSMAN 227 Abstracts 232 Reports ... 236 Reviews . .. 242 Edited by DR. J. Ross INNES, Medical Secretary of the British Leprosy Relief Association, 8 Portman Street. London, W.l, to whom aU communications should be sent. The Association does not accept responsibility for views expressed by writers. Contributors of original articles will receive 25 loose reprints free, but more formal bound reprints must be ordered at time of submitting the article, and the cost reimbursed later.
    [Show full text]
  • Military Dermatology, Chapter 14, Leprosy
    Leprosy Chapter 14 LEPROSY JAMES W. STEGER, M.D.* AND TERRY L. BARRETT, M.D.† INTRODUCTION HISTORY Leprosy in Antiquity Leprosy in Medieval and Renaissance Europe Modern Advances in the Study of Leprosy Leprosy in the U.S. Military EPIDEMIOLOGY MICROBIOLOGY Natural Reservoirs and Laboratory Transmission The Cell Wall Molecular Biology and Genetics IMMUNOLOGY Humoral Immunity Cell-Mediated Immunity The Lepromin Test LABORATORY DIAGNOSIS The Slit-Skin Examination Technique Bacterial Index Morphologic Index Cutaneous Nerve Biopsy Serologic Assays CLINICAL AND HISTOLOGICAL DIAGNOSTIC CRITERIA TREATMENT Paucibacillary Leprosy Multibacillary Leprosy The Most Potent Antileprosy Drugs Drug Resistance Microbial Persistence Promising New Drugs COMPLICATIONS: THE REACTIONAL STATES Reversal Reaction Erythema Nodosum Leprosum Downgrading Reaction Lucio’s Phenomenon VACCINATION LEPROSY AND ACQUIRED IMMUNODEFICIENCY SYNDROME SUMMARY *Captain, Medical Corps, U.S. Navy; Head, Dermatology Clinic, Naval Hospital, San Diego, California 92134-5000 †Captain, Medical Corps, U.S. Navy; Pathology and Dermatopathology Consultant, Naval Hospital, San Diego, California 92134-5000 319 Military Dermatology INTRODUCTION Leprosy (also called Hansen’s disease) is an in- one form to the next. These transitional forms arise fectious disease caused by Mycobacterium leprae that through fluctuations in the host’s immune system. affects principally the skin, the peripheral nervous Transitions from a higher to a lower immune status system, and certain other organs. Depending on are reactional states known as downgrading reac- their immune status, patients with leprosy may tions, the converse as reversal reactions. Both types present with a wide range of cutaneous and neu- of reactional states complicate therapy. An infected rological signs and symptoms. These signs and patient whose clinical presentation (usually a symptoms have been grouped together to delineate hypopigmented patch) is not diagnostic is said to leprosy into a spectrum of clinical forms or stages have indeterminate leprosy.
    [Show full text]
  • 2013 Jahresbericht 2013 Annual Report
    2013 Jahresbericht 2013 Annual Report Carl Schlettwein Stiftung 2 Carl Schlettwein Foundation 2 Jahresüberblick 2013 3 Overview of 2013 3 „Re-Figuring the South African Empire" 9 "Re-Figuring the South African Empire" 9 Basler Afrika Bibliographien 12 Basler Afrika Bibliographien 12 Jahresüberblick 2013 13 Overview of 2013 13 Öffentlichkeit und Partner 16 Publicity and Partners 12 Veranstaltungen 17 Events 17 Besucher, Gäste und Führungen 21 Visitors, Guests and Tours 21 Schenkungen 22 Donations 22 Bibliothek und Sammlungen 24 Library and Collections 24 Archiv und Dokumentation 34 Archive and Documentation 34 Verlag 44 Publishing House 44 Inhalt Mitarbeiterinnen und Mitarbeiter 50 Staff Members 50 Kurzporträts 51 Short Portraits 51 Contents Veröffentlichungen, Vorträge, Lehre 55 Publications, Lectures, Courses 55 Berichte und Beiträge 58 Reports and Contributions 58 Werkschau "zuHören/Listening in" 59 Show Case "zuHören/Listening in" 59 Afrikareise 62 Africa Trip 62 Schweizer Jugend Forscht 2013 65 Swiss Youth in Science 2013 65 Bibliothekspraktikum 68 Library Internship 68 Impressum 69 Imprint 69 Inhalt Contents 3 Carl Schlettwein Stiftung Carl Schlettwein Foundation Jahresüberblick 2013 Overview of 2013 Im Berichtsjahr wurde die im letzten Jahr in In the year under review, the separation die Wege geleitete Trennung der Geschäfte initiated the prior year between the affairs der Stiftung und des Betriebs der Basler Af- of the foundation and the activities of the rika Bibliographien operativ umgesetzt. Für Basler Afrika Bibliographien was
    [Show full text]
  • Mycobacterium Leprae
    Lepr Rev (1987) 58, 105- 118 Studies of reactivity of some Sri Lankan population groups to antigens of Mycobacterium leprae. I. Reactivity to lepromin A M R M PINTO, * N B ERIYAG AMA* & V PEMAJAYANTHAt * Department of Microbiology , Faculty of Medicine, University of Peradeniya, Peradeniya; Division of Biometry, Cen tral Agricul­ t tural Research Institute, Gannoruwa , Sri Lanka Accepted fo r publication 14 August 1986 Summary This paper reports a survey of lepromin reactivity in adult population groups in areas at three different elevations (geographical localities) in central Sri 7 Lanka, using a lepromin A with a bacillary content of 3 or 4 x 10 bacilli/ml. The patterns of reactivity observed with both Fernandez and Mitsuda reactions were clearly bimodal and similar in all areas. The distributions of reactions were divisible into 'non-reactor' ('negative') and 'reactor' ('positive') components. For both Fernandez and Mitsuda reactivity the demarcation between non-reactor and reactor components seemed to be best made at a reaction size of 3 mm. The mode of reactors of the Fernandez reaction was at 3-6 mm, and of the Mitsuda reaction at 5-8 mm. Both types of reactivity showed no change with increase of age. Fernandez reactivity showed no evidence of any change with sex, race, BeG vaccination status or geographical area. Mitsuda reactivity did not seem to be affected by race or geographical area, but there seemed to be possible changes with sex and BeG vaccination status. Even so, there seems to be a trend for higher reaction sizes in males, and the BeG vaccinated, with both types of reactivity.
    [Show full text]
  • Downloadable Tools That Align with Longitudinal Engagement of Stakeholders from Vulnerable Or Hard-To- Existing NFP Care Domains and Link to Other NFP Resources
    Implementation Science 2019, 14(Suppl 1):27 https://doi.org/10.1186/s13012-019-0878-2 MEETINGABSTRACTS Open Access Proceedings from the 11th Annual Conference on the Science of Dissemination and Implementation Washington, DC, USA. 3-5 December 2018 Published: 25 March 2019 I1 importance of meeting the needs of end-users where they are, a sen- Introduction timent echoed by other plenary speakers across the three plenary Gila Neta1, David Chambers1, Lisa Simpson2 panel sessions. These sessions included one focusing on scaling up 1National Cancer Institute, Rockville, MD, USA; 2AcademyHealth, effective interventions particularly in low resource settings, and two Washington, DC, USA focusing on building capacity for D & I science within community Implementation Science 2019, 14(Suppl 1):I1 and healthcare settings, respectively. Each plenary panel enabled ac- tive dialogue between presenters and with the audience, further In December 2018, the National Institutes of Health (NIH) and Acade- deepening the discussion and surfacing many of the nuances and is- myHealth co-hosted the 11th Annual Conference on the Science of Dis- sues in D&I science. Major themes across all the plenaries included semination and Implementation (D&I) in Health, “Scaling up Effective the importance of building relationships and trust among stake- Health and Healthcare: Advancing the Research Agenda and Necessary holders, focusing on the end-user’s needs, working across sectors to Infrastructure.” Reflecting increased interest in the field and growth in facilitate implementation and scale up, and understanding the value our research community, we had record attendance with nearly 1,300 of processes to inform generalizable strategies for implementation.
    [Show full text]
  • Histoire De La Santé Publique Et Communautaire En Afrique. Le Rôle Des Médecins De La Mission Suisse En Afrique Du Sud1*
    Gesnerus 72/1 (2015) 135–158 Histoire de la santé publique et communautaire en Afrique. Le rôle des médecins de la mission suisse en Afrique du Sud1* Hines Mabika Summary It was not Dutch settlers nor British colonizers who introduced public and community health practice in north-eastern South Africa but medical doctors of the Swiss mission in southern Africa. While the history of medical knowl- edge transfer into 19th–20th century Africa emphasises colonial powers, this paper shows how countries without colonies contributed to expand western medical cultures, including public health. The Swiss took advantage of the lo- cal authorities’ negligence, and implemented their own model of medicaliza- tion of African societies, understood as the way of improving health stan- dards. They moved from a tolerated hospital-centred medicine to the practice of community health, which was uncommon at the time. Elim hospital’s physi- cians moved back boundaries of segregationist policies, and sometime gave the impression of being involved in the political struggle against Apartheid. Thus, Swiss public health activities could later be seen as sorts of seeds that were planted and would partly reappear in 1994 with the ANC-projected na- tional health policy. Keywords: South Africa, Switzerland, Public Health, Medical Missions, Medical Apartheid. * L’auteur remercie les Profs V. Barras et. P. Gisel pour le soutien financier de leurs institutions lors de la rédaction de cet article dans le cadre de la coopération interfacultaire de l’Université de Lausanne, le Prof. H. Steinke (Berne) pour ses amicales suggestions et les deux éditeurs anonymes pour la pertinence de leurs commentaires.
    [Show full text]
  • An Epidemiologist's View of Leprosy KENNETH W
    Bull. Org. mond. Santg 1966, 34, 827-857 Bull. Wld Hlth Org. , An Epidemiologist's View of Leprosy KENNETH W. NEWELL1 While leprosy has been studied exhaustively by leprologists, it is only recently that persons in other disciplines have given this disease the attention it deserves. Various methods for its prevention and control are now being advocated and tested in thefield, and it appears reasonable for an epidemiologist to review the bases of current theories and to examine the evidence for existing hypotheses. This has been done by a review ofsome of the more recent literature. The conclusion is reached that the anergic, or factor N, hypothesis that has been evolved to relate the lepromin test to the findings in clinical leprosy appears to be the most promising, and that, if this hypothesis can be substantiated, it is unlikely that BCG vaccination can be a very useful tool for prevention. Many possibilities exist for epidemiological and laboratory research into this disease, which in many ways appears to be unique. INTRODUCTION theories on the subject. This has resulted in some emphasis and omissions that are hard to justify. Not only were leprosy patients walled up or Some basic observations well known to leprologists segregated in the past, but it would be fair to say that have been omitted; this could lead to difficulties in the leprologists and the subject of leprosy were also understanding by people who are unfamiliar with the cut off from the main body of medical thought and subject. Other apparently simple points have been research. Many pleas have been made, generally in described in detail, and this could be thought of as specialist publications read only by leprologists, for undignified and as " padding " by the leprosy expert.
    [Show full text]
  • 2016 FACULTY SCHOLARSHIP REPORT DESIGN and LAYOUT Nick Paulus Breanna Bugbee
    2016 FACULTY SCHOLARSHIP REPORT DESIGN AND LAYOUT Nick Paulus BreAnna Bugbee PHOTOGRAPHY Elizabeth Torgerson-Lamark/RIT PUBLISHED BY The Wallace Center - RIT Open Access Publishing OFFICE OF THE PROVOST www.rit.edu/provost/ 1 TABLE OF CONTENTS LETTER FROM THE PROVOST 3 B. THOMAS GOLISANO COLLEGE OF COMPUTING & INFORMATION SCIENCES 4 COLLEGE OF APPLIED SCIENCE & TECHNOLOGY 26 COLLEGE OF HEALTH SCIENCES & TECHNOLOGY 36 COLLEGE OF IMAGING ARTS & SCIENCES 42 COLLEGE OF LIBERAL ARTS 52 COLLEGE OF SCIENCE 74 SAUNDERS COLLEGE OF BUSINESS 94 GOLISANO INSTITUTE FOR SUSTAINABILITY 102 KATE GLEASON COLLEGE OF ENGINEERING 112 NATIONAL TECHNICAL INSTITUTE FOR THE DEAF 140 OTHER DEGREE GRANTING UNITS 160 MESSAGE FROM THE PROVOST RIT is now ranked among the best and brightest of the nation’s universities. The Carnegie Classification of Institutions of Higher Education moved RIT to a doctoral university status in 2016, due to the rapidly growing number of Ph.D. degrees awarded each year. This comes as no surprise to the faculty and students engaged in research, pedagogical undertakings and scholarly activities at RIT. The scholarly efforts within this report continue to have a profound impact within our local communities, the industries we collaborate with, and the world. This work, which ranges from making our university and our communities more sustainable, to understanding the very fabric of our universe, engages students in ways which prepare them for our ever- changing world. The growth of our research and scholarship is guided by our vision for the future, where imagination and the application of interdisciplinary skills will place our faculty and our students at the forefront of the global economy.
    [Show full text]