Clin Transl Allergy 2017, 7(Suppl 4):47 DOI 10.1186/s13601-017-0184-5 Clinical and Translational Allergy MEETING ABSTRACTS Open Access EAACI/ESCD Skin Allergy Meeting 2017 (SAM 2017) Zurich, Switzerland. 27 – 29 April 2017 Published: 15 December 2017 Thursday, 27 April 2017 O02 Assessment of aggregate consumer exposure to isothiazolinones O01 via cosmetics and detergents Methylisothiazolinone contact allergy: a real outbreak Elena Garcia Hidalgo, Natalie Von Goetz, Konrad Hungerbühler Luis Amaral1, Emidio Silva2, Marcio Oliveira3, Ana Paula Cunha4 ETH Zürich, Zürich, Switzerland 1Serviço de Imunoalergologia, Centro Hospitalar de São João E.P.E., Porto, Correspondence: Elena Garcia Hidalgo ‑
[email protected] Portugal; 2Serviço de Medicina do Trabalho e Saúde Ocupacional, Centro Clinical and Translational Allergy 2017, 7(Supple 4):O02 Hospitalar do Baixo Vouga E.P.E., Aveiro, Portugal; 3Serviço de Saúde Ocu‑ pacional, Centro Hospitalar de São João E.P.E., Porto, Portugal; 4Serviço de Background: Isothiazoliones can cause allergic contact dermati- Dermatologia, Centro Hospitalar de São João E.P.E., Porto, Portugal tis and are present in a variety of consumer products, such as cos- Correspondence: Luis Amaral ‑
[email protected] metics, detergents and do-it-yourself products. Skin sensitization Clinical and Translational Allergy 2017, 7(Supple 4):O01 is induced following dermal exposure to a sensitizer in an amount exceeding the sensitization threshold. The critical determinant of Background: Methylisothiazolinone (MI) is used as a preservative in exposure for evaluating skin sensitization risks is dose per unit area occupational, domestic products and, since 2005, in cosmetics. It is a of exposed skin.