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Irkutsk, Russian Federation 12th SAC SEMINAR COMBATING GLOBAL INFECTIONS 21-24 September 2009 Listvyanka- Irkutsk, Russian Federation 1 TABLE of CONTENTS General Information on the 12th SAC Seminar ____________________________ 3 Welcomes: - Chairman of Scientific Advisory Committee, International Science and Technology Center___________________________________________ 3 - Central Research Institute of Epidemiology _____________________ 4 - International Science and Technology Center (ISTC) ______________5 - Irkutsk State Medical University ______________________________ 8 Program__________________________________________________________ 9 Abstracts of Oral Presentations _______________________________________ 15 Abstracts of Poster Presentations _____________________________________ 42 Contact information __________________________________________ 63 2 On behalf of the Chairman of the Scientific Advisory Committee (SAC) of the International Science and Technology Center (ISTC), I would like to welcome all of you to participate in the twelfth SAC Seminar on “COMBATING GLOBAL DISEASES”. It is my great pleasure that so many experts and representatives, including young scientist and students, have attended this Semi- nar from the leading Russian and CIS research institutes, public and international organizations, research centers and universi- ties all the way to Irkutsk. SAC is determined to address the topic of global health issues, since this is becoming more and more important today, mostly due to the fast spread and the impact on humans, and also due to the possible bioterrorism. This has been evidenced by the recent emerging global spread of swine flu . At the previous SAC Seminar two years ago, SAC selected the subject of nuclear renaissance. This has been evidenced lately, since the number of newly nuclear power introducing countries becomes over fifty this year, whereas the number of already introduced countries is thirty one. Also some years ago, we took up the topic on PET technology, and this has been still stimulating the research on PET in Russia and other countries. For the next year we are thinking to hold the Seminar on risk management as another global issue. I do hope that this Seminar will provide a good opportunity for the participants to share with us the newest infor- mation on the current achievements and challenges that need to be addressed in this area. Also I hope that all the participants will be actively involved at this Seminar for the discussion in order to clearly identify the global health issues for the future. Finally I would like to express my sincere gratitude to all the colleagues for the preparatory work, conduction and management of this Seminar, especially to the International Science & Technology Center, the Central Research Institute of Epidemiology - Russian Ministry of Healthcare and Social, and Irkutsk State Medical University, for their great help and assistance. I wish you have a fruitful and successful meeting. Chairman of Scientific Advisory Committee, International Science and Technology Center Advisor, Ministry of Education, Culture, Sports, Science and Technology, Japan Director, Nuclear Technology and Education Center, Japan Atomic Energy Agency SUGIMOTO, Jun 3 Dear Colleagues, On behalf of the Organizing Committee let me welcome all the participants to the International Conference, which is dedicated this time to “Combating Global Diseases”, a topic which has been put on the list of research and applied activities of the Ministry for Public Health and Social Development of the Russian Federation for 2009. The growth of disease incidence with respect to viral hepatitis, tuberculosis, HIV/AIDS, viral enteric in- fections, on the one hand, and potential risk of bioterrorism on the other, pose a severe threat to global security today. New infectious diseases (i.e., newly detected), such as avian and pandemic flu are emerging; the need for prophylaxis of “re-emerging” infections (malaria, viral hemorrhagic fever) is be- coming more pressing while no steady tendencies to the sickness rate reduction in terms of cholera, anthrax, plague and other highly dangerous infections are observed. This conference will contribute to the practical implementation of the decisions, made by the G8 member- states during the summit meeting on combating global diseases (Saint Petersburg, 15-17 July, 2006), which suggest a global counterepidemic strategy. The guidelines, enclosed in the summit decisions, are targeted to global unified modernization of the public health systems: • Early diagnostics of newly emerging infections and prevention of their proliferation; • Construction and reinforcement of the relevant infrastructures; implementation of collective approaches to training specialists and to human resource strategy in the public health, especially in the developing countries; • Enhancement of the prophylactic component in combating global diseases; • Fund raising to implement global programs on combating infectious diseases; • Engagement of civilian institutions in counterepidemic activities; • Build-up of domestic potential in the developing countries to combat infectious diseases; • Raising the efficiency of population health protection measures in emergency situations. The above guidelines were taken as the basis to formulate the program and the list of basic topics to be ad- dressed during the conference. The conference will be attended by experts from the leading Russian/CIS research institutions, representatives of public and international organizations in the public health sector; specialists from research centers of the US, Canada, Japan, Germany, France, Hungary, who will make presentations. The program of the conference provides space for many challenging reports, covering topics like global infectious disease surveillance, including the use of molecular, information and com- munication technologies. Some topical presentations will be made on treatment of infectious diseases and identification of their resistance to drugs. A special focus of the conference will be on training and competency building of 4 specialists in the post-graduation phase of education – a separate session will be dedicated to young scientists. Being one of the conference organizers, the Central Research Institute of Epidemiology of Rospotrebnadzor is involved in an active collaboration with the World Health Organization, international centers and organizations, foreign institutes and universities. CRIE provides a platform for the following centers: center for zoonotic diseases, collaborating with WHO; Federal Research and Methodical Center for AIDS Control; Russian Centers for: nosocomial in- fections, meningococcosis, purulent meningitis, shigellosis, salmonellosis, viral hepatitis, control of the status of collective immunity to infections, treated by means of specific prophylaxis; Center for Molecular Diagnostics of Infectious Diseases. The Central Research Institute of Epidemiology of Rospotrebnadzor has a great research potential, em- ploying 6 members of RAMS, 42 doctors of science, 23 professors, 50 PhDs, 7 Honored Workers of RF Science, 6 State Award Laureates, 17 RF Government and Academy Award Laureates. The Institute acts as the Head Organization of the Research Council for Epidemiology, Infectious and Parasitic Dis- eases, established by a collective order, issued by the Health Ministry of the Russian Federation and RAMS, ensuring coordination and review of research on epidemiology and infection pathology problems, conducted in Russia. Today the Central Research Institute of Epidemiology under Rospotrebnadzor is one of the largest Rus- sian developers and manufacturers of products, alternative to imported ones, such as test-systems for detecting a wide spectrum of infectious pathogens (HIV, viral hepatitis, avian and highly pandemic flu, tuberculosis etc,) by means of molecular diagnostics. The use of the above-mentioned test-systems ensures epidemiological safety of the Russian Federation. Active involvement of the Institute’s staff con- tributes to successful investigation of outbreaks of infectious diseases in various regions of the Russian Federation. Through basic and applied research and development the Institute creates innovation tech- nologies of infectious disease diagnostics (biochips, nanotechnologies). I hope, that this Conference on “Combating Global Diseases” will initiate interesting discussions, which would contribute significantly to the global epidemic security. Dear colleagues, your active involvement in the Conference program will provide an added value to our efforts, focused on combating infectious diseases. Let me wish you further success in your profession. Co-Chair of the Organizing Committee of the Conference Director of Federal State Science Institution “Central Research Institute of Epidemiology” under Rospotrebnadzor academician of RAMS V.I. Pokrovsky 5 Dear Colleagues, I would like to cordially welcome you to the twelfth seminar of the Scientific Advisory Committee of the International Science and Technology Centre (ISTC). I am grateful that so many experts involved in health research and promotion have come to Irkutsk to take part in focused discussions on the topic of ‘Combating Global Infections’. I am also pleased to see that special attention has been paid to the active participation of young scien- tists and students in this seminar program. I thank the Irkutsk State Medical University for arranging the student participation. The subject of the seminar is highly topical. Health issues
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