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Boletín Vigilancia Tecnológica Sector Biomasa (4º Trimestre 2019)

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Boletín Vigilancia Tecnológica Sector Biomasa (4º Trimestre 2019) 34 Vigilancia Tecnológica NIPO: 116-19-007-8 4º trimestre 2019 PRODUCTOS BIOFARMACÉUTICOS: PROYECTOS EUROPEOS La biofarmacéutica destaca como uno sector de rápido crecimiento e interés dentro de la industria farmacéutica. Los biofármacos -que incluyen vacunas, alergénicos y terapias génicas- son biomoléculas desarrolladas mediante la biotecnología, la cual utiliza procesos biológicos para diseñar o fabricar medicamentos y otros productos valiosos. Los proyectos europeos en el ámbito de la biofarmacéutica vienen experimentando un extraordinario crecimiento desde las primeras covocatorias (Figura 1), habiéndose identificado 64 proyectos en el programa H2020. La Tabla 1 recoge los proyectos actualmente en curso. En la Figura 2 se muestran los países líderes de los proyectos del programa H2020 en este campo, siendo Reino Unido, España e Irlanda los situados a la cabeza de este Programa. 60 50 40 30 20 10 0 1PM 2PM 3PM 4PM 5PM 6PM 7PM H2020 (1984-1987) (1987-1991) (1990-1994) (1994-1998) (1998-2002) (2002-2006) (2007-2020) (2014-2020) Figura 1. Proyectos europeos financiados en los distintos Programas Marco y H2020 1 Tabla 1. Proyectos H2020 IM2PACT: Investigating Mechanisms and Models Predictive of Accessibility of Therapeutics (IM2PACT) into the brain Fecha de inicio: 01/01/2019 Fecha de finalización: 31/12/2023 Coordinador: The Chancellor, Masters and Scholars of Oxford Univ (Reino Unido) Newcotiana: Developing multipurpose nicotiana crops for molecular farming using new plant breeding techniques Fecha de inicio: 01/01/2018 Fecha de finalización: 30/06/2022 Coordinador: CSIC (España) iConsensus: Integrated control and sensing platform for biopharmaceutical cultivation process high-throughput development and production Fecha de inicio: 01/05/2018 Fecha de finalización: 30/04/2022 Coordinador: Kungliga Tekniska Hoegskolan (Suecia) iReceptor Plus: Architecture and tools for the query of antibody and T-cell receptor sequencing data repositories for enabling improved personalized medicine and immunotherapy Fecha de inicio: 01/01/2019 Fecha de finalización: 31/12/2022 Coordinador: Bar Ilan University (Israel) ORBIS: Open Research Biopharmaceutical Internships Support Fecha de inicio: 01/03/2018 Fecha de finalización: 28/02/2022 Coordinador: Univ Medyczny im Karola Marcinkowskiego W Poznaniu (Polonia) PEPPER: Industrial-scale plant-based protein production in a cell-free platform Fecha de inicio: 01/12/2019 Fecha de finalización: 30/11/2021 Coordinador: LenioBio GmbH (Alemania) Light4Sight: Light-activated carriers for the controlled delivery of therapeutic peptides in posterior segment eye diseases Fecha de inicio: 01/11/2019 Fecha de finalización: 31/10/2021 Coordinador: Queen Mary Univ London (Reino Unido) EuroNanoMed III: ERA-net on nanomedicine Fecha de inicio: 01/11/2016 Fecha de finalización: 31/10/2021 Coordinador: Instituto de Salud Carlos III (España) IL7RsignaTHER: Antibody-based IL-7R targeted therapies Fecha de inicio: 01/01/2020 Fecha de finalización: 30/06/2021 Coordinador: Instituto Medicina Molecular Joao Lobo Antunes (Portugal) PATGlycoPrint: Development of a new process analytical technology based on an innovative nanoplasmonic detection array for monitoring glycosylation of monoclonal antibodies Fecha de inicio: 01/05/2019 Fecha de finalización: 30/04/2021 Coordinador: Linkopings Univ (Suecia) GlycoMabs: Chemoenzymatic glyco-engineering of therapeutic monoclonal antibodies Fecha de inicio: 16/04/2019 Fecha de finalización: 15/04/2021 Coordinador: Asociación Centro de Investigación Cooperativa en Biociencias (España) SeaBest: Launching first large-scale organic seaweed-to-food cultivation and processing in EU Fecha de inicio: 01/03/2019 Fecha de finalización: 28/02/2021 Coordinador: Seaweed Energy Solutions AS (Noruega) LCxLCProt: Comprehensive two-dimensional liquid chromatography for the characterization of protein biopharmaceuticals at the protein level Fecha de inicio: 01/01/2020 Fecha de finalización: 31/12/2020 Coordinador: Univ Gent (Bélgica) CARBOMET: Metrology of Carbohydrates for Enabling European Bioindustries Fecha de inicio: 01/01/2017 Fecha de finalización: 31/12/2020 Coordinador: Univ Manchester (Reino Unido) AMECRYS: Revolutionising downstream processing of monoclonal antibodies by continuous template-assisted membrane crystallization Fecha de inicio: 01/10/2016 Fecha de finalización: 30/09/2020 Coordinador: Consiglio Nazionale delle Ricerche (Italia) MiChomAbs: Synthetic Mini-Chromosomes for Antibody production Fecha de inicio: 01/12/2019 Fecha de finalización: 31/05/2020 Coordinador: Ribbon Biolabs GmbH (Austria) Vigilancia Tecnológica 4º trimestre 2019 2 PHOTO-FLUOR: Enantioselective Carbon-Fluorine Bond Formation: A molecular editing approach toward drug discovery Fecha de inicio: 09/05/2018 Fecha de finalización: 09/05/2020 Coordinador: Institut Catala D’investigacio Quimica (España) PEARRL: Pharmaceutical Education And Research with Regulatory Links: Innovative drug development strategies and regulatory tools tailored to facilitate earlier access to medicines Fecha de inicio: 01/05/2016 Fecha de finalización: 30/04/2020 Coordinador: Univ Cork-Natl Univ Ireland (Irlanda) GlypStx: Glycoprotein-based inhibitors of shiga-like toxin Fecha de inicio: 01/02/2018 Fecha de finalización: 30/03/2020 Coordinador: Univ Leeds (Reino Unido) DiViNe: Sustainable downstream processing of vaccines through incorporation of nanobiotechnologies: Novel affinity ligands and biomimetic membranes Fecha de inicio: 01/03/2015 Fecha de finalización: 29/02/2020 Coordinador: Instituto de Biologia Experimental e Tecnologica (Portugal) MABIOS: The first microalgae platform for the production of anticancer biopharmaceuticals Fecha de inicio: 01/08/2019 Fecha de finalización: 31/01/2020 Coordinador: Microalgae Works BV (Países Bajos) 10 9 8 7 6 5 4 3 2 1 0 Israel Italia Suiza AustriaBélgica EspañaEstonia FranciaIrlanda Polonia Suecia Alemania Eslovenia Finlandia Noruega Portugal Dinamarca Paises Bajos Reino Unido República Checa Figura 2. Países líderes de los proyectos H2020 Vigilancia Tecnológica 4º trimestre 2019 3 PATENTES BIOENERGÍA Biocombustibles sólidos (pellets, biochars, bio RDFs, bio SRFs, etc.) Nº Publicación Solicitante (País) Contenido técnico Method and apparatus for processing biomass. In a process for the treatment of biomass, the moisture content of the biomass feedstock is reduced, if necessary, to less than 12%; the dried feedstock is fed in vacuumed portions to a heat treatment roasting furnace and roasted at heat treatment temperature in the range of 220-300°C, predetermined in function of the target calorific value of the end-product; the end- product is delivered from the roasting furnace to the cooler and cooled to below its ignition temperature, then withdrawn for further utilisation. Before feeding the first portion of the dried feedstock into the roasting furnace, the interior of the roasting Agricarbon KFT furnace is evacuated; the gaseous medium generated during roasting is disposed of; WO2019186216 (HU) and during heat treatment of the feedstock in the roasting furnace, the pressure in the roasting furnace is maintained continuously at a pressure exceeding 1.0 bar (a) by no more than 200 mbar(a). The drying air stream (a) used to reduce the moisture content of the raw material is warmed by the heating air stream (e) exiting the roasting furnace, the warmed-up cooling medium stream (f) used for cooling the end-product and the heat energy generated by the combustion of the gaseous medium generated during roasting; the cooling medium stream (f) used to cool the end-product is pre-cooled by the drying air stream (a) used to reduce the moisture content of the feedstock. The invention also concerns a device for implementing the biomass treatment method. Antl-autooxidative wood pellet binder. Formulations and methods of making wood pellets treated with lignin sulfonate as an anti-autooxidative component to reduce the rate of self-heating of bulk wood pellets. The lignin sulfonate may be used as a binder in the wood pellets or the wood pellets may be sprayed with lignin sulfonate for an WO2019229526 Borregaard AS (NO) encapsulated wood pellet. Wood pellets having the lignin sulfonate have a lowered potential of self-heating below high reactivity pellets and better structural durability during storage and transportation without adversely affecting the fuel value of the wood pellets. Solid fuel burner. A burner comprises a primary combustion chamber with means for adjusting the volume of the primary combustion chamber, a means of delivering solid fuel to the primary combustion chamber, and a secondary combustion chamber. The primary combustion chamber may have a grate with the means for adjusting the volume of the primary combustion chamber formed by a further grate. The secondary GB2573217 Brian Elliott (GB) combustion chamber may also have a grate. The primary combustion chamber may be directly above the secondary combustion chamber so that during combustion, solid fuel from the primary combustion chamber passes into the secondary combustion chamber. The burner may have a removeable ash tray which retains fully combusted solid fuel. The burner is suitable for burning biomass fuel and may comprise an induction chamber to extract heat to a connected heat load such as a water boiler, space heater, or oven. Biomass auto combustion chamber. A combustion chamber comprises an internally hollow tank containing biomass to be combusted and gasified, air supply means to Microsystemfuel EP3423751 supply air inside
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