THE MAIN TEA ETA US DAN20170304317A1 MA TA AT MAN AT MAN ( 19) United States (12 ) Patent Application Publication ( 10) Pub . No. : US 2017/ 0304317 A1 DiMaggio (43 ) Pub . Date : Oct. 26 , 2017

(54 ) DIETARY SUPPLEMENTS FOR MUSCLE A61K 31 /366 ( 2006 .01 ) GROWTH AND STRENGTH A61K 31 /4525 ( 2006 .01 ) ( 52 ) U .S . CI. (71 ) Applicant: Robert DiMaggio , Henderson , NV CPC . . .. . A61K 31/ 5685 (2013 .01 ) ; A61K 31/ 4525 (US ) (2013 . 01 ) ; A61K 9/ 48 (2013 .01 ) ; A61K 31/ 366 (72 ) Inventor : Robert DiMaggio , Henderson , NV ( 2013 .01 ) (US ) (57 ) ABSTRACT (21 ) Appl. No. : 15 /643 , 894 A compound is provided for oral administration of dehy droepiandrosterone (DHEA ) derivatives to a human so as to ( 22 ) Filed : Jul . 7 , 2017 improve at least one of adrenal hormonal balance , improved immune system function , reduction of adipose tissue , skel Related U .S . Application Data etal muscle growth , reduction of abdominal bloating , (63 ) Continuation - in -part of application No . 14 /736 , 103 , improved recovery from training , increased strength , and increased endurance . The compound includes a first portion filed on Jun . 10 , 2015 . comprised of any one of 3a -enanthoxy - 5a -androstan -17 (60 ) Provisional application No . 62 / 360 , 241, filed on Jul. one , 3b - undecyloxy - 5a -androstan - 17 - one, and 3b -hydroxy 8 , 2016 . androstane - 3b - ol- one . A second portion of the compound is comprised of 6 , 7 -dihydrogergamottin . A third portion is Publication Classification comprised of piperine , and a fourth portion is comprised of (51 ) Int. Ci. any one or more of rice flour , gelatin , magnesium stearate , A61K 31/ 5685 ( 2006 . 01 ) and silica . The compound preferably is administered in A61K 9 /48 ( 2006 .01 ) capsule form one or two times in a 24 -hour period .

- 104

THI wa miche 5 -DHEA Heptanoyl Chloride missed5 -DHEA Enanthated Patent Application Publication Oct . 26, 2017 Sheet 1 of 2 US 2017/ 0304317 A1

?? ????????????? 5 -DHEA Heptanoyl Chloride 5 -DHEA Enanthated FIGFIG . . 11

2018

???.???ift? Or?? +???? ???. 1 - DHEA Heptanoyl Chloride 1 -DHEA Enanthated FIG . 2

?? 312 ?? ?? 4 -DHEA Heptanoyl Chloride 4 -DHEA Enanthated??? FIG . 3 Patent Application Publication Oct . 26, 2017 Sheet 2 of 2 US 2017/ 0304317 A1

- 404

?????? ??? ??? re * 6-) R -DHEA SUPER R -DHEA (Reduced R - DHEA ) FIG . 4

508 - ? 19 -Nor - DHEA Heptanoyl??????? Chloride 19 Nor- DHEA Enanthated FIG . 5

612 \ ???- ?????? Epiandrosterone Hendecanoic Acid Epiandrosterone FIG . 6 Undecanoate US 2017 /0304317 A1 Oct. 26 , 2017

DIETARY SUPPLEMENTS FOR MUSCLE compound . In addition , DHEA sulfate does not restore the GROWTH AND STRENGTH balance of the adrenal steroids discussed above . As a result , frequent and larger doses of DHEA must be taken to achieve PRIORITY a desired result . [ 0001] This continuation - in -part application claims the [ 0008 ] DHEA is also metabolized in the body to one of benefit of and priority to U . S . patent application , entitled several compounds including , for example , etiocholanolone “ Method For DHEA Enanthate Processing, ” filed on Jun . 10 , ( 5 -beta - androstan - 3 - alpha - ol- 17 -one ) , beta etiocholanolone 2015 having application Ser. No . 14 /736 , 103 and U . S . ( 5 -beta -androstan - 3 -beta - ol- 17 -one ) , androsterone ( 5 - alpha Provisional Patent Application No . 62 / 360 , 241 filed on Jul. androstan - 3 - alpha -ol - 17 -one ) , epiandrosterone ( 5 -alpha - an 8 , 2016 . drostan - 3 - beta - ol- 17 -one ) , 7 -keto - DHEA , 7 - alpha -hydroxy DHEA , 7 - beta -hydroxy - DHEA , androstenedione, estrone , FIELD and estradiol. [0002 ] The field of the present disclosure generally relates [0009 ] There is great individual variability in the metabo to dietary supplements . More particularly , the field of the lism of oral DHEA . The DHEA metabolites estrone and present disclosure relates to compounds for oral adminis estradiol can result in negative estrogenic side effects for tration of dehydroepiandrosterone (DHEA ) derivative to males including growth of male breast tissue , known as improve human physical performance . gynecomastia . Some individuals have poor bioavailability of DHEA as a result of sulfation in the liver , and large doses BACKGROUND must be taken to elicit any desired effects . These increased doses of DHEA can result in increased conversion to estrone [ 0003 ] The adrenal gland produces many steroid hor and estradiol, with resulting negative side effects . mones . These steroid hormones play a major role in many body processes including , for example, skeletal muscle [ 0010 ] What is needed , therefore, are compounds which growth , red blood cell production (erythropoiesis ), regula provide the beneficial effects of high DHEA levels in the tion of glucose and insulin levels , and cellular aging . The body for extended periods of time, yet reduce the undesired steroids produced by the adrenal gland can be divided into DHEA side effects discussed above . three groups: glucocorticoids, which influence carbohydrate metabolism ; mineralocorticoids, which control electrolyte SUMMARY and water balance; and sex steroid hormones. [0004 ] Glucocorticoids such as cortisol regulate catabo [0011 ] A compound is provided for oral administration of lism of skeletal muscle proteins into amino acids. These dehydroepiandrosterone (DHEA ) derivatives to a human so amino acids are then transported to the liver and converted as to improve at least one of adrenal hormonal balance , into glucose during gluconeogenesis . Excessive amounts of improved immune system function, reduction of adipose glucocorticoids can result in higher blood glucose and tissue , skeletal muscle growth , reduction of abdominal insulin levels and can contribute to increased body fat and bloating , improved recovery from training , increased type II diabetes . Glucocorticoids are also known to play a strength , and increased endurance . The compound includes role in the aging process by increasing cellular and mito a first portion comprised of any one of 3a - enanthoxy - 5a chondrial breakdown. Mineralocorticoids such as aldoster androstan - 17 - one , 3b - undecyloxy - 5a - androstan - 17 -one , and one help the body to retain sodium and water. Excesses of 3b -hydroxy -androstane - 3b - ol- one . A second portion of the mineralocorticoids can result in hypertension and cardio compound is comprised of 6 ,7 -dihydrogergamottin (DHB ). vascular disease . The sex steroid hormones include adrenal A third portion is comprised of piperine , and a fourth portion androgens and DHEA . Adrenal androgens oppose the is comprised of any one or more of rice flour, gelatin , actions of glucocorticoids and result in skeletal muscle magnesium stearate , and silica . In one embodiment, the first anabolism ( the opposite action of catabolism ), reductions in portion may be comprised of substantially 100 mg of blood glucose and insulin levels , reduction in body fat, and 3a - enanthoxy -5a - androstan - 17 -one , the second portion may are believed to decrease the rate of cellular aging and be comprised of substantially 15 mg of DHB 45 % , and the increased red blood cell production . DHEA production by third portion may be comprised of substantially 5 mg of the adrenal glands is known to decline markedly as aging piperine . In another embodiment, the first portion may be progresses . comprised of substantially 50 mg of 3b - undecyloxy -5a [ 0005 ] With normal younger adults , all three groups of androstan - 17 - one , the second portion may be comprised of adrenal steroids are produced in a healthy balance . As people substantially 15 mg of DHB 45 % , and the third portion may age , however , less DHEA is produced resulting in relatively be comprised of substantially 5 mg of piperine . In still greater amounts of glucocorticoids and mineralocorticoids, another embodiment, the first portion may be comprised of resulting in a disruption of a healthy hormone balance . substantially 50 mg of 3b - hydroxy -androstane - 3b - ol- one , [0006 ] DHEA supplementation is believed to be useful in the second portion may be comprised of substantially 15 mg treatment of aging and obesity , and to stimulate erythropoi of DHB , and the third portion may be comprised of sub esis and skeletal muscle anabolism . In addition , supplemen stantially 5 mg of piperine . The compound preferably is tal DHEA may help restore the balance of adrenal steroids. administered in capsule form one or two times in a 24 - hour [0007 ]. DHEA is commonly used as a dietary supplement. period . Unfortunately , DHEA is rapidly metabolized by liver [0012 ] In an exemplary embodiment, a compound for oral enzymes , such as sulfotransferases. Sulfotransferases rap administration of dehydroepiandrosterone (DHEA ) deriva idly convert much of the supplementary DHEA into DHEA tives to a human comprises a first portion comprised of one sulfate , which is quickly excreted from the body and is not or more prohormones ; a second portion comprised of one or effective as an anti - aging , muscle - building or fat reduction more compounds to increase the bioavailability of the one or US 2017 /0304317 A1 Oct. 26 , 2017 more prohormones; and a third portion comprised of one or tially 15 mg of DHB 45 % , and the third portion is comprised more compounds to decrease a conversion of testosterone to of substantially 5 mg of piperine . In another exemplary estrogen . embodiment, the first portion is comprised of substantially [0013 ] In another exemplary embodiment, the first portion 50 mg of 3b -hydroxy -androstane - 3b - ol- one , the second por is comprised of 3a - enanthoxy -5a -androstan - 17 -one , the sec tion is comprised of substantially 15 mg of DHB , and the ond portion is comprised of 6 , 7 -dihydrogergamottin (DHB ) third portion is comprised of substantially 5 mg of piperine . 45 % , and the third portion is comprised of piperine. In In another exemplary embodiment, the compound is admin another exemplary embodiment, the first portion is com istered in capsule form one or two times in a 24 -hour period . prised of substantially 100 milligrams (mg ) of 3a - enanthoxy - 5a - androstan - 17 - one , the second portion is BRIEF DESCRIPTION OF THE DRAWINGS comprised of substantially 15 mg of DHB 45 % , and the third [ 0017 ] The drawings refer to embodiments of the present portion is comprised of substantially 5 mg of piperine . In disclosure in which : another exemplary embodiment, the compound further com [0018 ] FIG . 1 is a chemical formula illustrating an exem prises any one or more of rice flour, gelatin , magnesium plary embodiment of a process for producing 5 -DHEA stearate , and silica . In another exemplary embodiment, the enanthate, according to the present disclosure ; compound is administered in capsule form one or two times [0019 ] FIG . 2 is a chemical formula illustrating an exem in a 24 - hour period . plary embodiment of a process for producing 1 -DHEA [0014 ] In another exemplary embodiment, the first portion enanthate in accordance with the present disclosure ; is comprised of 3b -undecyloxy - 5a -androstan - 17 - one , the 10020 ] FIG . 3 is a chemical formula illustrating an exem second portion is comprised of DHB 45 % , and the third plary embodiment of a process for producing 4 - DHEA portion is comprised of piperine. In another exemplary enanthate, according to the present disclosure ; embodiment, the first portion is comprised of substantially [ 0021 ] FIG . 4 is a chemical formula illustrating an exem 50 mg of 3b -undecyloxy -5a -androstan - 17 - one , the second plary embodiment of a process for producing Super portion is comprised of substantially 15 mg of DHB 45 % , R -DHEA (Reduced R -DHEA ) , according to the present and the third portion is comprised of substantially 5 mg of disclosure ; piperine . In another exemplary embodiment, the compound [0022 ] FIG . 5 is a chemical formula illustrating an exem is further comprised of any one or more of rice flour , gelatin , plary embodiment of a process for producing 19 Nor- DHEA magnesium stearate , and silica . In another exemplary Enanthated in accordance with the present disclosure; and embodiment, the compound is administered in capsule form 100231 FIG . 6 is a chemical formula illustrating an exem one or two times in a 24 -hour period . plary embodiment of a process for producing Epiandroster [ 0015 ] In another exemplary embodiment, the first portion is comprised of 3b -hydroxy -androstane - 3b - ol- one , the sec one Undecanoate , according to the present disclosure . ond portion is comprised of DHB , and the third portion is [ 0024 ] While the present disclosure is subject to various comprised of piperine . In another exemplary embodiment , modifications and alternative forms, specific embodiments the first portion is comprised of substantially 50 mg of thereof have been shown by way of example in the drawings 3b - hydroxy - androstane- 3b - ol- one , the second portion is and will herein be described in detail . The invention should comprised of substantially 15 mg of DHB , and the third be understood to not be limited to the particular forms portion is comprised of substantially 5 mg of piperine. In disclosed , but on the contrary , the intention is to cover all another exemplary embodiment, the compound is further modifications, equivalents , and alternatives falling within comprised of any one or more of rice flour, gelatin , mag the spirit and scope of the present disclosure . nesium stearate , and silica . In another exemplary embodi ment, the compound is administered in capsule form one or DETAILED DESCRIPTION two times in a 24 - hour period . [0025 ] In the following description , numerous specific [0016 ] In an exemplary embodiment, a compound for oral details are set forth in order to provide a thorough under administration of dehydroepiandrosterone (DHEA ) deriva standing of the present disclosure . It will be apparent, tives to a human so as to improve at least one of adrenal however, to one of ordinary skill in the art that the invention hormonal balance , improved immune system function , disclosed herein may be practiced without these specific reduction of adipose tissue , skeletal muscle growth , reduc details . In other instances, specific numeric references such tion of abdominal bloating , improved recovery from train as " first compound, " may be made. However , the specific ing , increased strength , and increased endurance comprises numeric reference should not be interpreted as a literal a first portion comprised of any one of 3a - enanthoxy - 5a sequential order but rather interpreted that the " first com androstan - 17 -one , 3b -undecyloxy - 5a -androstan -17 -one , and pound ” is different than a " second compound. ” Thus , the 3b -hydroxy - androstane - 3b -ol - one ; a second portion is com specific details set forth are merely exemplary . The specific prised of 6 , 7 - dihydrogergamottin (DHB ); a third portion is details may be varied from and still be contemplated to be comprised of piperine ; and a fourth portion is comprised of within the spirit and scope of the present disclosure. The any one or more of rice flour, gelatin , magnesium stearate , term “ coupled ” is defined as meaning connected either and silica . In another exemplary embodiment, the first directly to the component or indirectly to the component portion is comprised of substantially 100 mg of through another component. Further, as used herein , the 3a -enanthoxy -5a -androstan - 17 -one , the second portion is terms “ about, " " approximately, " or " substantially ” for any comprised of substantially 15 mg of DHB 45 % , and the third numerical values or ranges indicate a suitable dimensional portion is comprised of substantially 5 mg of piperine . In tolerance that allows the part or collection of components to another exemplary embodiment, the first portion is com function for its intended purpose as described herein . prised of substantially 50 mg of 3b - undecyloxy -5a -an - (0026 ] In general, the present disclosure describes com drostan - 17 - one, the second portion is comprised of substan pounds for oral administration of dehydroepiandrosterone US 2017 /0304317 A1 Oct. 26 , 2017

(DHEA ) to a human so as to improve at least one of adrenal a wide range of benefits , and thus is advantageous for cutting hormonal balance, improved immune system function , body fat, as well as keeping muscle gains lean during a body reduction of adipose tissue , skeletal muscle growth , reduc mass building cycle . tion of abdominal bloating , improved recovery from train [0030 ] FIG . 2 is a chemical formula illustrating an exem ing , increased strength , and increased endurance . Exemplary plary embodiment of a process 208 for producing 1 -DHEA embodiments of compounds for oral administration of enanthate in accordance with the present disclosure . The DHEA generally comprise one or more prohormones in process 208 for producing 1 - DHEA enanthate is substan combination with one or more compounds to increase the tially similar to the process 104 , illustrated in FIG . 1 , with bioavailability of the one or more prohormones . In some the exception that the process 208 begins by placing a embodiments , the compounds for oral administration of desired portion of unprocessed 1 -DHEA , in raw material DHEA may further comprise one or more compounds that form , into the solvent and allowing the portion to dissolve operate to decrease a conversion of testosterone to estrogen . completely into the solvent. Asmentioned above , the solvent Preferably , the compounds are administered in capsule form preferably is comprised of Benzene. Next , Pyridine may be one or two times in a 24 -hour period . mixed into the solution of 1 - DHEA and Benzene. Heptanoyl [0027 ] FIG . 1 is a chemical formula illustrating an exem Chloride may then be slowly added to the solution so as to plary embodiment of a process 104 for producing 5 - DHEA drive the chemical reaction illustrated in FIG . 2 . The Hep enanthate , according to the present disclosure. The process tanoyl Chloride preferably may be added slowly , such as by 104 begins by placing a desired portion of unprocessed way of adding drops to the solution , so as to allow all of the DHEA , in raw material form into a solvent and allowing the unprocessed 1 -DHEA to react , thereby producing 1 -DHEA DHEA to completely dissolve into the solvent. Preferably , enanthate as desired . the solvent comprises Benzene . Once the DHEA is suitably [0031 ] As will be recognized , 1 - DHEA is a naturally dissolved into the solvent, a first fluid comprising Pyridine occurring DHEA isomer which does not convert to testos may be mixed into the solution . A reaction of the portion of terone or estrogen . Rather, 1 -DHEA converts to non -estro unprocessed DHEA may be caused by adding a second fluid genic 1 - testosterone at a rate generally less than 2 % . In comprising Heptanoyl Chloride to the solution . As will be addition , 1 -DHEA is known to convert to 1 -androstenediol , appreciated , the Heptanoyl Chloride preferably is added which gives rise to potent muscle building due to nitrogen slowly , such as by way of adding drops to the solution , so as retention , as well as muscle hardening and strength gains . to allow all of the unprocessed DHEA to react. As indicated Also associated with 1 -androstenediol is a reduction of in FIG . 1 , reaction of the solution with the Heptanoyl abdominal bloating , as well as improved recovery from Chloride produces 5 -DHEA enanthate . As will be appreci heavy training . Further , 1 - DHEA does not activate estrogen ated , although 5 - DHEA enanthate produced by way of the receptors, as does DHEA , and thus 1 - DHEA is suitable for process 104 has a double bond located in the 5th position , stacking with other estrogenic steroids, such as by way of 5 - DHEA enanthate may be considered to comprise non - limiting example , 4 -DHEA , so as to promote clean " generic ” or regular DHEA . gains in muscle tissue . [0028 ] Although DHEA has been popular since the 1980s [0032 ] As with other DHEA isomers , 1 -DHEA is naturally due to an ability to increase energy and wellbeing when occurring , non - toxic , and exhibits mild side - effects . Tempo taken at a dosage of between 50 and 100 mg/ day , more rary side -effects typically include oily skin , reduced fertility , recently higher dosages have become popular in an attempt and increased hair shedding . A notable side -effect is a to improve body composition . It will be recognized that suppression ofnatural testosterone production , which makes higher dosages of DHEA generally give rise to mild anabolic Post Cycle Therapy (PCT ) a necessity after running a and thermogenic effects , making DHEA popular among 1 -DHEA cycle . Some trainees have reported a degree of trainees attempting to reduce body fat by way of training and lethargy when supplementing with 1 - DHEA ; however, dieting. Supplementation with DHEA has been shown to stacking 1 - DHEA with DHEA or 4 -DHEA is well known to exhibit good muscle sparing, anti -catabolic properties dur decrease perceived lethargy due to supplementing with ing calorie deficient diets , as well as improved exercise 1 - DHEA alone . Thus, 1 - DHEA is generally considered to be endurance and recovery from training . Further, DHEA is a very safe , legal, and effective lean muscle building agent. associated with improvements in immune system function in [0033 ] FIG . 3 is a chemical formula illustrating an exem trainees . plary embodiment of a process 312 for producing 4 -DHEA [ 0029 ] As is well known , DHEA generally converts to enanthate , according to the present disclosure . The process testosterone at a rate of substantially 1 % . Further, DHEA 312 begins by placing a desired portion of unprocessed exhibits a relatively high conversion rate to 5 -androstenediol 4 -DHEA , in raw material form , into a solvent and allowing and 7 -oxo -DHEA . The 5 - androstenediol produces mild the 4 -DHEA to completely dissolve into the solvent. As androgenic and anabolic effects associated with DHEA mentioned with respect to the processes 104 and 208 , the supplementation , while the 7 - oxo - DHEA gives rise to ther solvent use in the process 312 illustrated in FIG . 3 preferably mogenic properties suitable for reducing body fat in train comprises Benzene . Once the 4 -DHEA is suitably dissolved ees . The mild androgenic properties of DHEA rarely pro into the solvent, a first fluid comprising Pyridine may be duce hair loss or acne. Despite possessing moderate mixed into the solution . A reaction of the portion of unpro estrogenic properties , DHEA rarely produces gynecomastia cessed 4 -DHEA may be initiated by introducing Heptanoyl or other undesirable phenomena associated with hormone Chloride into the solution . Upon adding the Heptanoyl based supplementation . DHEA supplementation is fre Chloride slowly , such as by way of adding drops to the quently associated with elevated energy or motivational solution , the reaction of the solution with the Heptanoyl energy , which in some cases may present as anxiety or Chloride produces 4 - DHEA enanthate . sleeplessness in more sedentary trainees . It will be appreci [ 0034 ] As with other DHEA isomers , 4 -DHEA is a natu ated that the balanced hormonal properties of DHEA provide rally occurring DHEA isomer , although a double bond in the US 2017 /0304317 A1 Oct. 26 , 2017

4th position dramatically differentiates 4 - DHEA from the piperine . In an embodiment, an exemplary dietary supple other isomers . As is well known , 4 -DHEA converts to ment is comprised of 100 milligrams (mg ) of 3a - enanthoxy 4 -androstenediol , instead of 5 -androstenediol , as in the case 5a - androstan - 17 - one , 15 mg of 6 , 7 - dihydrogergamottin of 5 -DHEA , thereby boosting the anabolic potency of 45 % , and 5 mg of piperine . Further , the dietary supplement 4 -DHEA to more than two times greater than regular DHEA . may be comprised of any one or more of rice flour, gelatin , Similarly , 4 -DHEA also exhibits a higher conversion rate to magnesium stearate, and silica , without limitation . It is testosterone as compared to regular DHEA , while also envisioned that the exemplary dietary supplement may be lacking calorie burning thermogenic properties , thereby administered orally in the form of capsules taken one or two offering superior calorie retention for noticeable gains in t imes in a 24 -hour period . strength , recovery from training , lean tissue growth , and [0039 ] As will be appreciated , DHB is a natural furano weight gain . coumarin found principally in grapefruit juice . Along with [0035 ) Generally , 4 - DHEA exhibits a mild estrogen con the chemically related compound bergamottin , DHB is version which may be easily balanced with a non -aromatiz believed to be responsible for the " grapefruit juice effect, " ing steroid such as androsterone or 1 -DHEA . As with other wherein consumption of the juice may affects the metabo DHEA isomers, 4 -DHEA is naturally occurring , non - toxic , lism of a variety of compounds, including many pharma and exhibits mild side - effects, such as oily skin , reduced ceutical drugs. Chemically , bergamottin and DHB are fertility , abdominal bloating , and increased hair shedding . A inhibitors of some isoforms of the cytochrome P450 notable side -effect is a suppression of natural testosterone enzyme, particularly CYP3A4 , thereby preventing oxidative production , which makes PCT a necessity after running a metabolism of certain compounds by the enzyme, and 4 -DHEA cycle . As will be appreciated , 4 -DHEA is consid resulting in an elevated concentration of the compounds in ered to be generally a very safe , legal , and effective lean the bloodstream . It will be recognized that although the muscle building agent. grapefruit juice effect often is considered to be a negative [0036 ] FIG . 4 is a chemical formula illustrating an exem interaction , some current research has found potential ben plary embodiment of a process 404 for producing Super efits of cytochrome P450 inhibition , such as increasing the R - DHEA (Reduced R - DHEA ), according to the present oral bioavailability of various prohormone compounds , such disclosure . As will be appreciated , R - DHEA is referred to as as the above -mentioned 3a - enanthoxy - 5a -androstan - 17 - one . “ Reduced DHEA ” because it is a 5a -reduced metabolite of As will be further appreciated , piperine has been found to DHEA , and is also commonly referred to as androsterone . inhibit CYP3A4 and P - glycoprotein , enzymes important for The term “ Super ” indicates a fatty ester attachment to the the metabolism and transport of xenobiotics and metabo steroid molecule so as to improve bioavailability . Super lites. Thus , piperine may further increase the bioavailability R -DHEA is a naturally occurring hormone that does not of various prohormone compounds , thereby increasing their convert to testosterone within the body, but instead converts effectiveness as described herein . to dihydrotestosterone (DHT ) . Similar to testosterone , DHT [0040 ] FIG . 5 is a chemical formula illustrating an exem is associated with masculine traits, such as aggression , sex plary embodiment of a process 508 or producing 19 Nor drive , and physical strength . Further , DHT does not convert DHEA Enanthated in accordance with the present disclo to estrogen , and thus DHT is associated with reduced body sure . The process 508 begins by placing a desired portion of fat and reduced water retention , making DHT an excellent unprocessed 19 Nor - DHEA , in raw material form , into a steroid for increasing muscular hardness and vascularity . solvent and allowing the 19 Nor - DHEA to completely [ 0037 ] Moreover, R -DHEA stackswell with 5 - DHEA and dissolve into the solvent. As with processes described above , 4 -DHEA , wherein the R -DHEA operates to reduce subder the solvent used in the process 508 preferably comprises mal water retention , thereby creating a “ dry ” and hard Benzene . Once the 19 Nor- DHEA is suitably dissolved into appearance . Strength gains typically are noticeable with the solvent, a first fluid comprising Pyridine may be mixed R -DHEA due to its strong androgenic effect which activates into the solution . A reaction of the portion of unprocessed 19 the central nervous system , manifesting as increased confi Nor- DHEA may be initiated by very slowly introducing dence and an “ alpha male ” feeling in sexual and social Heptanoyl Chloride into the solution , such as by adding activities. The strong androgenic action of R -DHEA sup drops to the solution . The reaction of the solution with the ports libido and erection hardness , thereby countering sexu Heptanoyl Chloride produces 19 Nor -DHEA enanthate . ally suppressive side -effects due to other steroids. Further, [0041 ] As will be appreciated , 19 Nor- DHEA , also known the powerful androgenic effect of R -DHEA also blocks as 3b - enanthoxy - 19 -nor - androst- 4 - ene - 17 -one or Decaster estrogenic side - effects , thereby preventing and reversing one , generally comprises testosterone initially having a gynecological phenomena due to other steroids. Side -effects methyl group removed from a key position on its molecular due to R -DHEA generally are limited to androgenic side backbone . This slight alteration of the chemical structure of effects , such as oily skin , acne , and increased hair shedding , testosterone is known to reduce DHT- related side effects although such side - effects are usually mild and temporary. associated with testosterone , such as prostate issues, bald [0038 ] In some embodiments , an exemplary dietary ing , acne , as well as the estrogenic side effects , such as supplement is comprised of a first portion comprising one or gynecological phenomena . more prohormones , a second portion comprised of one or 10042 ] As is well known , 19 Nor- DHEA is a relatively more compounds to increase the bioavailability of the one or new compound that is a two -step precursor to 19 -nor more compounds, and a third portion comprised of one or testosteron , also known as Nandrolone . One problem with more compounds to decrease a conversion of testosterone to existing precursors to Nandrolone, such as " regular" 19 -nor estrogen . In some embodiments , the first portion may be DHEA , is that during production of regular 19 Nor- DHEA , comprised of 3a -enanthoxy -5a -androstan -17 -one , the sec purity may be compromised due to an inherent instability of ond portion may be comprised of 6 , 7 - dihydrogergamottin 19 Nor- DHEA . The instability of 19 Nor- DHEA generally 45 % (DHB ), and the third portion may be comprised of causes some of the material to be converted to other isomers , US 2017 /0304317 A1 Oct. 26 , 2017 as well as other unknown impurities during production . portion comprising one or more prohormones , a second Another problem is that regular 19 Nor - DHEA has a very portion comprised of one or more compounds to increase the short half - life , which results in poor bioavailability . bioavailability of the one or more compounds , and a third [0043 ] Unlike regular 19 Nor- DHEA , enanthated 19 Nor portion comprised of one or more compounds to decrease a DHEA has been found to exhibit improved bioavailability, conversion of testosterone to estrogen . In some embodi as well as improving purity during production , while also ments , the first portion may be comprised of 3b -undecyloxy generally mimicking the benefits of 19 - nor -testosterone . 5a- androstan - 17 - one , the second portion may be comprised Enanthated 19 Nor -DHEA operates to increase muscle tone of DHB 45 % , and the third portion may be comprised of and density , as well as decreasing overall levels of body fat, piperine . In one embodiment, an exemplary dietary supple by helping the body use any consumed proteins more ment is comprised of 50 mg of 3b -undecyloxy -5a -androstan efficiently . Further , enanthated 19 Nor - DHEA is also known 17 -one , 15 mg of DHB 45 % , and 5 mg of piperine . The to decrease recovery times following injury and increase dietary supplement may be further comprised of any one or stamina during exertion . Enanthated 19 Nor -DHEA more of rice flour , gelatin , magnesium stearate , and silica , increases muscle glycogen repletion and improve blood without limitation . It is contemplated that the exemplary stream oxygenation after tough exercise , thereby enabling dietary supplement may be administered orally in the form athletes to train for longer periods . Thus , observations of capsules taken one or two times in a 24 -hour period . suggest that enanthated 19 Nor -DHEA is effective in [0048 ] In some embodiments , the first portion may be improving healing of torn muscles and damaged bones. comprised of 3b -hydroxy - androstane -3b - ol- one , the second Further, enanthated 19 Nor -DHEA is associated with portion may be comprised of DHB , and the third portion increased feelings of competitiveness and aggression , which may be comprised of piperine . In one embodiment, an may be advantageous during sporting events . exemplary dietary supplement is comprised of 50 mg of [ 0044 ] FIG . 6 is a chemical formula illustrating an exem 3b -hydroxy -androstane - 3b -ol -one , 15 mg of DHB , and 5 mg plary embodiment of a process 612 for producing Epi of piperine. Any one or more of rice flour, gelatin , magne androsterone Undecanoate , according to the present disclo sium stearate , and silica may comprise the dietary supple sure. As is well known , Epiandrosterone is a precursor to ment, without limitation . Further, the exemplary dietary Stanolone , a powerful steroid hormone . Epiandrosterone is supplement may be administered orally in the form of a natural metabolite of DHEA by way of 5a -reductase capsules taken one or two times in a 24 - hour period . enzyme, also known as 3b -hydroxy - etioallocholan - 17 -one . [0049 ] While the invention has been described in terms of Epiandrosterone typically occurs naturally in most mam particular variations and illustrative figures, those of ordi mals and is excreted in urine as a normal part of human nary skill in the art will recognize that the invention is not metabolism . limited to the variations or figures described . In addition , [0045 ] As illustrated in FIG . 6 , the process 612 begins by where methods and steps described above indicate certain placing a desired portion of Epiandrosterone , in raw material events occurring in certain order, those of ordinary skill in form , into a solvent and allowing the Epiandrosterone to the art will recognize that the ordering of certain steps may completely dissolve into the solvent. In one embodiment, the be modified and that such modifications are in accordance solvent comprises Benzene . Once the Epiandrosterone is with the variations of the invention . Additionally , certain of suitably dissolved into the solvent, a first fluid comprising the steps may be performed concurrently in a parallel Pyridine may be mixed into the solution . A reaction of the process when possible , as well as performed sequentially as portion of unprocessed Epiandrosterone may be caused by described above . To the extent there are variations of the adding a second fluid comprising Hendecanoic Acid to the invention , which are within the spirit of the disclosure or solution . In one embodiment , the Hendecanoic Acid is added equivalent to the inventions found in the claims, it is the slowly by adding drops to the solution and allowing all of intent that this patent will cover those variations as well . the unprocessed Epiandrosterone to react. As indicated in Therefore , the present disclosure is to be understood as not FIG . 6 , reaction of the solution with the Hendecanoic Acid limited by the specific embodiments described herein , but produces Epiandrosterone Undecanoate . only by scope of the appended claims. [0046 ] Once in the human body, Epiandrosterone converts to Stanolone , which is known to be a very androgenic What is claimed is: hormone . Thus, Epiandrosterone is known to provide health 1 . A compound for oral administration of dehydroepi benefits , such as, but not necessarily limited to , weight loss , androsterone (DHEA ) derivatives to a human , comprising : muscle growth , and improved immune system function , a first portion comprised of one or more prohormones; although hair loss may be a concern . Epiandrosterone does a second portion comprised of one ormore compounds to not aromatize to estrogen , thus leading to relatively reduced increase the bioavailability of the one or more prohor bloating and gynecological phenomena. Further, although mones ; and Epiandrosterone is known to improve strength gains and a third portion comprised of one or more compounds to muscle density, Epiandrosterone is not quite as anabolic as decrease a conversion of testosterone to estrogen . other known prohormones . Thus , Epiandrosterone generally 2 . The compound of claim 1 , wherein the first portion is is best -suited for use during a body fat cutting cycle or comprised of 3a - enanthoxy - 5a - androstan - 17 -one , the sec alongside a prohormone that helps build muscle mass during ond portion is comprised of 6 , 7 - dihydrogergamottin (DHB ) a bulking phase for a balanced strength and size stack . In 45 % , and the third portion is comprised of piperine . additional , Epiandrosterone appears to have some immedi 3 . The compound of claim 2 , wherein the first portion is ate neurological effects , thereby producing a positive impact comprised of substantially 100 milligrams (mg ) of on strength and aggression . 3a -enanthoxy -5a -androstan - 17 - one, the second portion is [0047 ] As disclosed above , in some embodiments, an comprised of substantially 15 mg of DHB 45 % , and the third exemplary dietary supplement may be comprised of a first portion is comprised of substantially 5 mg of piperine. US 2017 /0304317 A1 Oct. 26 , 2017

4 . The compound of claim 3 , wherein the compound 14 . A compound for oral administration of dehydroepi further comprises any one or more of rice flour , gelatin , androsterone (DHEA ) derivatives to a human so as to magnesium stearate , and silica . improve at least one of adrenal hormonal balance , improved 5 . The compound of claim 4 , wherein the compound is immune system function , reduction of adipose tissue, skel administered in capsule form one or two times in a 24 -hour etal muscle growth , reduction of abdominal bloating , period . improved recovery from training , increased strength , and 6 . The compound of claim 1 , wherein the first portion is increased endurance, comprising : comprised of 3b -undecyloxy - 5a - androstan - 17 - one , the sec a first portion comprised of any one of 3a -enanthoxy -5a ond portion is comprised of DHB 45 % , and the third portion androstan - 17 - one , 3b - undecyloxy - 5a -androstan - 17 is comprised of piperine . one, and 3b -hydroxy - androstane - 3b -ol -one ; 7. The compound of claim 6 , wherein the first portion is comprised of substantially 50 mg of 3b -undecyloxy -5a a second portion is comprised of 6 , 7 - dihydrogergamottin androstan - 17 - one , the second portion is comprised of sub ( DHB) ; stantially 15 mg of DHB 45 % , and the third portion is a third portion is comprised of piperine ; and comprised of substantially 5 mg of piperine . a fourth portion is comprised of any one or more of rice 8 . The compound of claim 7 , wherein the compound is flour, gelatin , magnesium stearate , and silica . further comprised of any one or more of rice flour , gelatin , 15 . The compound of claim 14 , wherein the first portion magnesium stearate , and silica . is comprised of substantially 100 mg of 3a - enanthoxy - 5a 9 . The compound of claim 8 , wherein the compound is androstan - 17 - one , the second portion is comprised of sub administered in capsule form one or two times in a 24 - hour stantially 15 mg of DHB 45 % , and the third portion is period . comprised of substantially 5 mg of piperine. 10 . The compound of claim 1 , wherein the first portion is 16 . The compound of claim 14 , wherein the first portion comprised of 3b -hydroxy - androstane -3b - ol- one , the second is comprised of substantially 50 mg of 3b - undecyloxy -5a portion is comprised of DHB , and the third portion is androstan - 17 -one , the second portion is comprised of sub comprised of piperine . stantially 15 mg of DHB 45 % , and the third portion is 11 . The compound of claim 10 , wherein the first portion comprised of substantially 5 mg of piperine. is comprised of substantially 50 mg of 3b -hydroxy -andros tane - 3b - ol - one , the second portion is comprised of substan 17. The compound of claim 14 , wherein the first portion tially 15 mg of DHB , and the third portion is comprised of is comprised of substantially 50 mg of 3b -hydroxy - andros substantially 5 mg of piperine . tane - 3b -ol - one , the second portion is comprised of substan 12 . The compound of claim 11 , wherein the compound is tially 15 mg of DHB , and the third portion is comprised of further comprised of any one or more of rice flour , gelatin , substantially 5 mg of piperine. magnesium stearate, and silica . 18 . The compound of claim 15 , 16 , or 17, wherein the 13 . The compound of claim 12 , wherein the compound is compound is administered in capsule form one or two times administered in capsule form one or two times in a 24 -hour in a 24 -hour period . period . * * * *