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CURRICULUM VITAE RENA ZHENG, M.D., Ph.D

CURRICULUM VITAE RENA ZHENG, M.D., Ph.D

CURRICULUM VITAE RENA ZHENG, M.D., Ph.D. [email protected]

EDUCATION AND TRAINING University Section of Hematology and Medical Oncology 7/2018-6/2021 Hematology/Oncology Fellowship (anticipated)

Boston University Department of Medicine 6/2015- 6/2018 Internal Medicine Residency

University of Perelman School of Medicine M.D. 8/2007-5/2015 PhD. Immunology 8/2009-12/2013

University of Pennsylvania of Arts and Sciences 8/2003-5/2007 B.A. Biology and Chemistry Minor Summa cum laude and Departmental Honors in Biology

HONORS AND AWARDS Boston University Internal Medicine Residency Best Senior Talk Award 2018 Excellence in Teaching by a Junior Resident 2017 Arnold P. Foundation Humanism and Excellence in Teaching Award 2016 Gold Humanism Honor Society 2016 Perelman School of Medicine Mary Ellis Bell Prize 2014 Phi Beta Kappa Honors Society 2008 University of Pennsylvania Dean’s List 2004-2007

RESEARCH Quality Improvement Project, 1/2017-5/2017 • Developed an intervention to increase provider and patient awareness of employment resources and patient referrals for employment-related encounters • Advisor: Pablo Buitron De La Vega, M.D.

Research rotation, Brigham and Women’s Hospital 7/2016-12/2017 • Applied principles of cloning in designing an improved viral vector for use in CRISPR-Cas9 targeted deletion in hematopoietic stem cells • Investigated mechanism of cytokine independence in clonal expansion of mutations in clonal hematopoiesis of indeterminate potential (CHIP) • Advisor: Benjamin Ebert, M.D., Ph.D.

Research rotation, University of Pennsylvania 11/2014-12/2014 • Utilized Perl computer programming language to examine the association of noncoding DNA elements and single nucleotide polymorphisms from lipid genome-wide association studies. • Advisor: Benjamin Voight, Ph.D.

Thesis, University of Pennsylvania 1/2010-12/2013 • Characterized the expression, genome-wide target genes, and function of GATA transcription factors in the mouse liver. • Advisor: Gerd A. Blobel, M.D., Ph.D.

Senior thesis and undergraduate research, University of Pennsylvania 1/2004-5/2007 • Evaluated the role of Cdc42-interacting protein-4 as a link between the actin and microtubule networks at the immunological synapse of natural killer cells. Advisor: Jordan S. Orange, M.D., Ph.D.

PROFESSIONAL SOCIETY MEMBERSHIP American Society of Hematology 2018- present American Physician Scientist Association 2015- present Medical Society 2015- present American College of Physicians 2015-2018

GRANTS Hemostasis and Thrombosis Training Grant T32 H107971 2011-2013

PUBLICATIONS Peer-Reviewed Articles Zheng R, Rebolledo-Jaramillo B, Zong Y, Wang L, Russo P, Hancock W, Stanger, BZ, Hardison, RC, Blobel GA. (2013) Function of GATA Factors in the Adult Mouse Liver. PLoS ONE. 8 (12): e83723. PMCID: PMC3867416.

Banerjee PP, Pandey R, Zheng R, Suhoski M, Monaco-Shawver L, Orange JS. (2007) Cdc42-interacting protein–4 functionally links actin and microtubule networks at the cytolytic NK cell immunological synapse. The Journal of Experimental Medicine. 204(10): 2305-2320. PMCID: PMC2118451.

Reviews Zheng R and Blobel GA. (2010) GATA Transcription Factors and Cancer. Genes and Cancer, 1 (12): 1178-88. PMCID: PMC3092280.

Abstracts Zheng R, Staron A, Jia, J, Zeitler, K, Rajendran I, Buitron de la Vega P. (2017) Promoting Patient Health by Expanding Jobs-Related Care Coordinator Encounters [Poster]. Massachusetts Medical Society Research Poster Symposium. December 1. Waltham, MA.

Zheng R, Kennedy, J, Ebert, B. (2017) Developing an improved combination vector for tracking CRISPR/Cas9 targeted cells [Poster]. Boston University Evans Department of Medicine Research Days. October 12. Boston, MA.

Zheng R, Rebolledo-Jaramillo B, Hardison RC, Blobel GA. (2013) The role of GATA and FOG proteins in the adult mouse liver [Poster]. American Physician Scientists Association Annual Meeting, April 26-28, Chicago, IL.

Zheng R, Rebolledo-Jaramillo B, Hardison RC, Blobel GA. (2012) The role of GATA4 in regulating hepatocyte specific genes in the adult mouse liver [Poster]. FASEB Liver Biology Scientific Research Conference, July 29-August 3, Snowmass Village, CO.

Zheng R, Gregory GD, Kavi H, Blobel GA. (2010) Regulation of hepatic gene and microRNA expression by the GATA-4/FOG-1/NuRD pathway [Poster]. 61st Annual American Association for the Study of Liver Diseases Liver Meeting, October 29- November 2, Boston, MA.

INVITED TALKS “Clonal hematopoiesis of indeterminate potential – CHIP-ing away at the genetics of myelodysplastic syndrome.” Boston University Internal Medicine Residency Program Senior Talk May 3, 2018, Boston, MA

“Are CAR-T cells ALL that is needed for a cure?” Boston University Internal Medicine Residency Program Bite Sized Teaching November 3, 2016, Boston, MA

“Transcriptional control of the adult liver by GATA and FOG proteins” University of Pennsylvania Combined Degree Annual Retreat August 8, 2013, Villanova, PA

EXTRACURRICULAR ACTIVITIES Boston University Internal Medicine Residency Program Scholarship 2017-2018 Committee • Resident member • Organized an event to bring interns, junior and senior residents together to discuss research opportunities at Boston University

Cyracom Language Solutions Proficiency Assessment 2016 • Achieved Advanced Professional in Mandarin Chinese on language exam • Enables direct communication with patients speaking Mandarin Chinese in clinical encounters

Boston Medical Center RN-MD Communication Task Force 2016-2017 • MD member • Collaborated with RNs and MDs to develop strategies to improve communication between nurses and physicians

Perelman School of Medicine Medical Education Club 2014-2015 • Leader of the History and Physical Project • Developed course to teach first year medical students the basic interviewing and physical examination skills

Penn Med Music on Call 2012 • Co-Chair • Organized concerts performed by medical students, graduate students, residents and faculty at the Perelman School of Medicine, University of Pennsylvania

Penn Language Link Interpreter 2007-2015 • Interpreter in Mandarin Chinese • Interpreted on oncology inpatient service, emergency department and neurology consults

HOBBIES AND OUTSIDE INTERESTS • Playing piano o Chamber musician, collaborating with other instrumentalists o Performed Hungarian Rhapsody for Cello and Piano by David Popper at Carnegie Hall, City, November 2013 • Running o Member of Run BMC running group o Competed in 5k, 8k and 10k races • Knitting o Knit scarves, hats, mittens, and blankets