Anesthetic List for MH-Susceptible Patients Anesthetic Agent Choice for the MH-Susceptible Patient

The following anesthetic agents are known triggers of MH and are not safe for use in MH-susceptible patients:

Unsafe Anesthetic Agents for MHS Patients What Drugs trigger MH and are Not Safe? Inhaled General Anesthetics Choroform (Trichloromethane, Methyltrichloride) Desflurane Enflurane Halothane Isoflurane Methoxyflurane Sevoflurane Trichloroethylene Xenon (Rarely Used) Depolarizing Muscle Relaxants Trigger MH Succinylcholine (Suxamethonium)

All other anesthetic agents outside of these two categories of Volatile anesthetic agents and depolarizing muscle relaxants are considered safe (see below for a sample).

Safe Anesthetic Agents for MH Patients

Barbiturates / Intravenous Narcotics (Opioids) Anxiety Relieving Medications Anesthetics Alfentanil (Alfenta) Ativan (Lorazepam) Diazepam Anileridine Centrax Etomidate (Amidate) Codeine (Methyl Morphine) Dalmane (Flurazepam) Hexobarbital Diamorphine Halcion (Triazolam) Ketamine (Ketalar) Fentanyl (Sublimaze) Klonopin Methohexital (Brevital) Hydromorphone (Dilaudid) Librax Midazolam Meperidine (Demerol) Librium (Chlordiazepoxide) Pentobarbital Methadone Midazolam (Versed) Propofol (Diprivan) Morphine Paxipam (Halazepam) Thiopental (Pentothal) Naloxone Restoril (Temazepam) Oxycodone Serax (Oxazepam) Inhaled Non-Volatile General Anesthetic Phenoperidine Tranxene (Clorazepate) Nitrous Oxide Remifentanil Valium (Diazepam) Sufentanil (Sufenta Local Anesthetics Amethocaine Safe Muscle Relaxants Articaine Arduan (Pipecuronium) Bupivicaine Curare (The active ingredient is Dibucaine Tubocurraine) Etidocaine Gallamine Eucaine Metocurine Lidocaine (Xylocaine) Mivacron (Mivacurium) Levobupivacaine Neuromax (Doxacurium) Mepivicaine (Carbocaine) Nimbex (Cisatracurium) Procaine (Novocain) Norcuron (Vecuronium) Prilocaine (Citanest) Pavulon (Pancuronium) Ropivacaine Tracrium (Atracurium) Stovaine Zemuron (Rocuronium)