Energies 2015, 8, 4755-4801; doi:10.3390/en8064755 OPEN ACCESS energies ISSN 1996-1073 www.mdpi.com/journal/energies Review Systematic Methods for Working Fluid Selection and the Design, Integration and Control of Organic Rankine Cycles—A Review Patrick Linke 1,*, Athanasios I. Papadopoulos 2,† and Panos Seferlis 3,† 1 Department of Chemical Engineering, Texas A&M University at Qatar, P.O. Box 23874, Education City, 77874 Doha, Qatar 2 Chemical Process and Energy Resources Institute, Centre for Research and Technology-Hellas, Thermi, 57001 Thessaloniki, Greece; E-Mail:
[email protected] 3 Department of Mechanical Engineering, Aristotle University of Thessaloniki, P.O. Box 484, 54124 Thessaloniki, Greece; E-Mail:
[email protected] † These authors contributed equally to this work. * Author to whom correspondence should be addressed; E-Mail:
[email protected]; Tel.: +974-4423-0251; Fax: +974-4423-0011. Academic Editor: Roberto Capata Received: 1 March 2015 / Accepted: 15 May 2015 / Published: 26 May 2015 Abstract: Efficient power generation from low to medium grade heat is an important challenge to be addressed to ensure a sustainable energy future. Organic Rankine Cycles (ORCs) constitute an important enabling technology and their research and development has emerged as a very active research field over the past decade. Particular focus areas include working fluid selection and cycle design to achieve efficient heat to power conversions for diverse hot fluid streams associated with geothermal, solar or waste heat sources. Recently, a number of approaches have been developed that address the systematic selection of efficient working fluids as well as the design, integration and control of ORCs.