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39Th Annual Meeting Thank you to the 2013 ASHI Corporate Supporters Abbott Molecular Art Robbins Instruments Bio-Rad Laboratories DiaSorin, Inc. Elsevier GenDx Histogenetics Immucor Life Technologies Linkage Biosciences Inc. MLC Group, LLC mTilda HLA Software Specialists National Marrow Donor Program Olerup, Inc. Omixon Biocomputing One Lambda Inc., a part of Thermo Fisher Scientific Inc. STEMCELL Technologies Inc. Final Program 3 Table of Contents General Information .....................................5 ASHI Program Planning Committee. 9 Abstract Reviewers. 10 Board of Directors .....................................13 Corporate Supporters ...................................14 Exhibitor Directory. 15 Award Winners .......................................27 Schedule at a Glance ...................................34 Abstracts ...........................................42 Hotel and Exhibit Floor Plans ..............................95 4 Chicago, Illinois • Sheraton Chicago Hotel and Towers • November 17 – 21, 2013 General Information Registration Registration is located on the Lobby Level to the left of the main entrance. Sunday, November 17 Noon – 7:30 PM Monday, November 18 7:00 AM – 4:00 PM Tuesday, November 19 7:30 AM – 6:00 PM Wednesday, November 20 8:00 AM – 6:00 PM Thursday, November 21 8:00 AM – 10:30 AM Speaker Ready Room The Speaker Ready Room is located in Parlor D on the Lobby Level, Level 3. Sunday, November 17 5:00 PM – 7:00 PM Monday, November 18 7:00 AM – 4:00 PM Tuesday, November 19 7:00 AM – 4:30 PM Wednesday, November 20 7:00 AM – 4:30 PM Thursday, November 21 7:30 AM – 10:30 AM Exhibits/Internet Café Exhibits and Internet Café are located in the River Exhibition Hall on the First Floor. Exhibit and Poster Viewing Hours Monday, November 18 9:15 AM – 10:15 AM 1:00 PM – 2:15 PM 3:15 PM – 4:15 PM 5:30 PM – 7:00 PM Tuesday, November 19 9:15 AM – 10:15 AM 1:00 PM – 2:15 PM 3:15 PM – 4:15 PM Wednesday, November 20 9:45 AM - 10:45 AM Poster Mounting Times Sunday, November 17 3:00 PM – 7:00 PM Monday, November 18 7:00 AM – 9:00 AM Poster Dismounting Time Wednesday, November 20 Noon – 2:00 PM (Any poster still in place at 2:00 PM will be discarded.) Final Program 5 General Information ADA Compliance ASHI fully complies with the legal requirements of the Americans with Disabilities Act rules and regulations. If any participant is in need of special accommodations, please notify the hotel and indicate the type of assistance needed. ASHI cannot ensure the availability of appropriate assistance without advance notice. Cameras and Cell Phones No cameras of any kind are permitted inside educational session rooms. Any violation of this policy may result in the offender being removed from the meeting. As a courtesy to fellow attendees, please turn off cell phones during educational sessions. Meeting Objectives The 39th ASHI Annual Meeting has been designed to provide participants with a comprehensive review of a variety of topics related to the fields of genomics, immunogenetics, immunology, histocompatibility, and transplantation. The keynote address will set the stage with a discussion of the next generation of transplantation – engineering autologous tissues from pleuripotent stem cells. Plenary and symposium sessions will examine the relationship between immunogenetics and human population history, our diseases and their treatments; new findings in the quest for tolerance in transplantation; current strategies for improving outcomes in stem cell transplantation in the US and Europe; and new roles for complement in clinical transplantation and in the laboratory. Workshop sessions are designed to provide participants with practical information that can be utilized in their laboratories and transplant programs. Workshop topics will include a report of findings from the 2012 antibody consensus conference in Rome, an overview of next generation sequencing platforms, how to cope with information technology and results reporting, non-HLA antibodies, quality assurance for modification of assays, ethical dilemmas in transplantation, and statistical analysis for clinical research studies. Case studies in solid organ and stem cell transplantation provide attendees with informative presentations of challenges that laboratories face in providing testing for complex patients. Abstract and poster sessions provide attendees the opportunity to learn about clinical and basic research projects that could change future laboratory and clinical practice. After attending this meeting, participants should be able to identify important roles for immunogenetics that reach beyond transplantation, new roles for complement within transplantation, new possibilities for achieving tolerance, and current best practices in hematopoietic stem cell transplantation. Participants will be able to critically assess various aspects of laboratory testing, from detection of clinically relevant anti-HLA and non-HLA antibodies, to the very latest methods in HLA typing, to managing, reporting and analyzing the results. 6 Chicago, Illinois • Sheraton Chicago Hotel and Towers • November 17 – 21, 2013 Evaluation Participants must complete an evaluation in order to receive a certificate documenting credits earned for attending sessions. Sessions must be attended in their entirety. Partial credit is not available. Following the meeting, complete the evaluation and print your certificate by visiting http://2013.ashi-hla.org/ and clicking on the evaluation-specific icon. A username and password will be provided to you via e-mail upon the end of the meeting. Online meeting evaluations will be available from November 21 – December 21, 2013, after which time certificates will no longer be available. Physicians This activity has been planned and implemented in accordance with the Essential Areas and Policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the Institute for the Advancement of Human Behavior (IAHB) and the American Society for Histocompatibility & Immunogenetics. The IAHB is accredited by the ACCME to provide continuing medical education for physicians. AMA PRA Statement The IAHB designates this live activity for a maximum of 31.5 PRA Category 1 Credit(s)TM. Physicians should only claim credit commensurate with the extent of their participation in the activity. CHT, CHS, ABHI Diplomates The American Board of Histocompatibility and Immunogenetics has approved the 39th Annual Meeting content for a maximum of 27.5 contact hours and 4.125 continuing education credits (CEC); and has approved the Inspectors’ Training Workshop content for a maximum of 7.5 contact hours and 1.125 CEC, applicable for Certified Histocompatibility Technologists (CHT), Certified Histocompatibility Specialists (CHS), and ABHI Diplomates. Abstract Awards The following awards will be presented to the highest ranked abstracts accepted for oral presentations: ASHI Scholars, International Scholar, Best Solid Organ Case Study and Best Stem Cell Case Study. Three posters will be awarded the following: President’s Choice, Best Visual and Most Innovative. Internet Café – Supported by Abbott Molecular Complimentary computer stations are provided enabling you to access the Internet. The Internet Café is located in the River Exhibition Hall. Use of these computers is limited to 15 minutes. Final Program 7 Hotel Information Link @ Sheraton Cafe Located on Level 2 Free wireless, free workstations and online printing. Open daily from 6:00 AM until 5:00 PM FedEx Office Business Center Located across the hall from meeting registration Hours of Operations Monday – Friday 7:00 AM – 5:00 PM Saturday 8:00 AM – 3:00 PM Sunday 8:00 AM – 3:00 PM Special Services Large-format color printing, signs and banners, pre-convention printing and file assistance. 24 Hour guest access. Restaurants Shula’s Steak House Enjoy SHULA CUT steaks and fresh seafood at one of the top steak houses in America. Open daily from 5:30 pm to 10:30 pm Shula’s Bar is open daily 5:00 pm - 11:00 pm Chi Bar Located in the center of the lobby, Chi Bar is the ideal place to network and gather. Offering bar bites and cocktails, Chi Bar is in the center of all the action. Open daily from 3:00 pm – 11:00 pm. Link @ Sheraton Cafe Located just one level below the lobby, LINK @ Sheraton Cafe is the place to connect. Enjoy a variety of salads, sandwiches, paninis, soups, salads, breakfast pastries and coffee. Free wireless, free workstations and online printing. Open daily from 6:00 am - 5:00 pm. LB’s Bistro & Patisserie LB’s Bistro & Pâtisserie is the first restaurant of World Champion Pastry Chef Laurent Branlard. Combine fresh ingredients and simple yet unique combinations of flavors to create your own breakfast or lunch. Open daily for breakfast from 6:30 am - 11:00 am and for lunch from 11:30 am - 2:00 pm. 8 Chicago, Illinois • Sheraton Chicago Hotel and Towers • November 17 – 21, 2013 Program Planning Committee Program Planning Chair Workshops Chairs Amy Hahn, PhD, D(ABHI) Nebila Abdulwahab, MT(ASCP), CHT, CHS Albany Medical College Ohio State University Hospital Plenary and Symposia Sessions David Partlow, MS, MT, CHS Thomas Ellis, PhD, D(ABHI) MD Anderson Cancer Center University of Wisconsin-Madison Abstract Chairs Luis Hidalgo, PhD, D(ABHI) Patricia Campbell, MBChB, FRCP(UK), FRCP(C) University of Alberta Hospitals University of Alberta Hospitals Jill Hollenbach, PhD Annette Jackson, PhD, D(ABHI) Children’s Hospital Oakland Research Institute Johns Hopkins University School of Medicine Lawrence Jennings,
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